BLASTX 1.4.13-Paracel [2002-12-12]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= At4g31570.f
(8139 letters)
Database: BlastDB/NCBI/blast/db/2003_02_27_02_00_4/nr
1,347,713 sequences; 431,508,457 total letters
Searching...................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||T05113 hypothetical protein F28M20.240 - Arabidopsis t... 4772 0.0
ref|NP_173855.1| unknown protein; protein id: At1g24460.1 [... 162 8e-38
gb|AAF97958.1|AC000103_8 F21J9.12 [Arabidopsis thaliana]|gi... 149 9e-34
gb|AAC60300.1| kinesin-related protein [Xenopus laevis]|gi|... 126 5e-27
ref|NP_001804.1| centromere protein E; Centromere autoantig... 118 1e-24
>pir||T05113 hypothetical protein F28M20.240 - Arabidopsis
thaliana|gi|7270060|emb|CAB79875.1| putative protein
[Arabidopsis thaliana]|gi|3281870|emb|CAA19766.1|
putative protein [Arabidopsis
thaliana]|gi|15235996|ref|NP_194885.1| putative protein;
protein id: At4g31570.1 [Arabidopsis thaliana]
Length = 2712
Score = 4772 bits (12379), Expect = 0.0
Identities = 2528/2712 (93%), Positives = 2528/2712 (93%)
Frame = +1
Query: 1 MDKKKNRADPLAAGRQKLQQFRQKKADKGXXXXXXXXXXXXXXXXXXXXXXXEKHERKPD 180
MDKKKNRADPLAAGRQKLQQFRQKKADKG EKHERKPD
Sbjct: 1 MDKKKNRADPLAAGRQKLQQFRQKKADKGTDQKKDSKGSTSQGKSSKKSNKSEKHERKPD 60
Query: 181 TSAVSDEAQAPSPVTVGGATSHVNVAEEVVDSPQTSSDTKAHEYVSVHGSSSEPDALQPG 360
TSAVSDEAQAPSPVTVGGATSHVNVAEEVVDSPQTSSDTKAHEYVSVHGSSSEPDALQPG
Sbjct: 61 TSAVSDEAQAPSPVTVGGATSHVNVAEEVVDSPQTSSDTKAHEYVSVHGSSSEPDALQPG 120
Query: 361 HTTSNDGSEARKEVVNSENDISKSLSTEEENVKSINSGVAGTVDSLISDPADSEKGVTHD 540
HTTSNDGSEARKEVVNSENDISKSLSTEEENVKSINSGVAGTVDSLISDPADSEKGVTHD
Sbjct: 121 HTTSNDGSEARKEVVNSENDISKSLSTEEENVKSINSGVAGTVDSLISDPADSEKGVTHD 180
Query: 541 DASNVDGIFAASGNIAXXXXXXXXXXXXXXXKPHQPSSLQEYIPDVSLIRARGDQVTDVG 720
DASNVDGIFAASGNIA KPHQPSSLQEYIPDVSLIRARGDQVTDVG
Sbjct: 181 DASNVDGIFAASGNIAEGEGVEVEGGSGNVEKPHQPSSLQEYIPDVSLIRARGDQVTDVG 240
Query: 721 EMQEEDMEQFSELSAKAGVDKIATEERQTSYPAVVDSSASPSHFSEGSSVAFDTVELEGI 900
EMQEEDMEQFSELSAKAGVDKIATEERQTSYPAVVDSSASPSHFSEGSSVAFDTVELEGI
Sbjct: 241 EMQEEDMEQFSELSAKAGVDKIATEERQTSYPAVVDSSASPSHFSEGSSVAFDTVELEGI 300
Query: 901 NGNFRSQQIREAAELNEEKPETSIDFPNNRDHVLSAEPEESSVAEMASQLQLPESVSISG 1080
NGNFRSQQIREAAELNEEKPETSIDFPNNRDHVLSAEPEESSVAEMASQLQLPESVSISG
Sbjct: 301 NGNFRSQQIREAAELNEEKPETSIDFPNNRDHVLSAEPEESSVAEMASQLQLPESVSISG 360
Query: 1081 VLSHEETRKIDTLNLSAELTSAHVHEGRSVSFLQLMDIVKGLGQDEYQILCNAREAASST 1260
VLSHEETRKIDTLNLSAELTSAHVHEGRSVSFLQLMDIVKGLGQDEYQILCNAREAASST
Sbjct: 361 VLSHEETRKIDTLNLSAELTSAHVHEGRSVSFLQLMDIVKGLGQDEYQILCNAREAASST 420
Query: 1261 EPGTSSLERLREELFVSSTMEDILHVQLTEQSHLQIEFDHQHNQFVAEISQLRASYSAVT 1440
EPGTSSLERLREELFVSSTMEDILHVQLTEQSHLQIEFDHQHNQFVAEISQLRASYSAVT
Sbjct: 421 EPGTSSLERLREELFVSSTMEDILHVQLTEQSHLQIEFDHQHNQFVAEISQLRASYSAVT 480
Query: 1441 ERNDSLAEELSECQSKLYAATSSNTNLENQLLATEAQVEDFTAKMNXXXXXXXXXXXXXX 1620
ERNDSLAEELSECQSKLYAATSSNTNLENQLLATEAQVEDFTAKMN
Sbjct: 481 ERNDSLAEELSECQSKLYAATSSNTNLENQLLATEAQVEDFTAKMNELQLSLEKSLLDLS 540
Query: 1621 XXXXXFINLQVENDTLVAVISSMNDXXXXXXXXXXXXNYEIKHLSSELCNCKNLAAILKA 1800
FINLQVENDTLVAVISSMND NYEIKHLSSELCNCKNLAAILKA
Sbjct: 541 ETKEKFINLQVENDTLVAVISSMNDEKKELIEEKESKNYEIKHLSSELCNCKNLAAILKA 600
Query: 1801 EVEQFENTIGPLTDEKIHLVEEKYSLLGEAEKLQEELANCKTVVTLQEVENSNMKETLSL 1980
EVEQFENTIGPLTDEKIHLVEEKYSLLGEAEKLQEELANCKTVVTLQEVENSNMKETLSL
Sbjct: 601 EVEQFENTIGPLTDEKIHLVEEKYSLLGEAEKLQEELANCKTVVTLQEVENSNMKETLSL 660
Query: 1981 LTRQQTMFEENNIHLREENEKAHLELSAHLISETYLLSEYSNLKEGYTLLNNKLLKFQGE 2160
LTRQQTMFEENNIHLREENEKAHLELSAHLISETYLLSEYSNLKEGYTLLNNKLLKFQGE
Sbjct: 661 LTRQQTMFEENNIHLREENEKAHLELSAHLISETYLLSEYSNLKEGYTLLNNKLLKFQGE 720
Query: 2161 KEHLVEENDKLTQELLTLQEHMSTVEEERTHLEVELREAIARLDKLAEENTSLTSSIMVE 2340
KEHLVEENDKLTQELLTLQEHMSTVEEERTHLEVELREAIARLDKLAEENTSLTSSIMVE
Sbjct: 721 KEHLVEENDKLTQELLTLQEHMSTVEEERTHLEVELREAIARLDKLAEENTSLTSSIMVE 780
Query: 2341 KARMVDNGSADVSGLINQEISEKLGRSSEIGVSKQSASFLENTQYTNLEEVREYTSEFSA 2520
KARMVDNGSADVSGLINQEISEKLGRSSEIGVSKQSASFLENTQYTNLEEVREYTSEFSA
Sbjct: 781 KARMVDNGSADVSGLINQEISEKLGRSSEIGVSKQSASFLENTQYTNLEEVREYTSEFSA 840
Query: 2521 LMKNLEKGEKMVQNLEEAIKQILTDSSVSKSSDKGATPAVSKLIQAFXXXXXXXXXXXXN 2700
LMKNLEKGEKMVQNLEEAIKQILTDSSVSKSSDKGATPAVSKLIQAF N
Sbjct: 841 LMKNLEKGEKMVQNLEEAIKQILTDSSVSKSSDKGATPAVSKLIQAFESKRKPEEPESEN 900
Query: 2701 AQLTDDLSEADQFVSVNVQIRNXXXXXXXXXXNARKAGIQFNQLNDDRTSTNQRLEELNV 2880
AQLTDDLSEADQFVSVNVQIRN NARKAGIQFNQLNDDRTSTNQRLEELNV
Sbjct: 901 AQLTDDLSEADQFVSVNVQIRNLRGLLDQLLLNARKAGIQFNQLNDDRTSTNQRLEELNV 960
Query: 2881 EFASHQDHINVLEADTIESKVSFEALKHYSYELQHKNHDLELLCDSLKLRNDNISVENTE 3060
EFASHQDHINVLEADTIESKVSFEALKHYSYELQHKNHDLELLCDSLKLRNDNISVENTE
Sbjct: 961 EFASHQDHINVLEADTIESKVSFEALKHYSYELQHKNHDLELLCDSLKLRNDNISVENTE 1020
Query: 3061 LNKKLNYCSLRIDXXXXXXXXXXXXXTSFLSTMEEQLVALQDESERAMMVEHELTSLMSE 3240
LNKKLNYCSLRID TSFLSTMEEQLVALQDESERAMMVEHELTSLMSE
Sbjct: 1021 LNKKLNYCSLRIDELEIQLENLQQNLTSFLSTMEEQLVALQDESERAMMVEHELTSLMSE 1080
Query: 3241 FGEAVVRLDDCLLRSGTSGAHTGLDMTKRISGSVDVAVNVIEDLKEKLEAAYVKHESTSN 3420
FGEAVVRLDDCLLRSGTSGAHTGLDMTKRISGSVDVAVNVIEDLKEKLEAAYVKHESTSN
Sbjct: 1081 FGEAVVRLDDCLLRSGTSGAHTGLDMTKRISGSVDVAVNVIEDLKEKLEAAYVKHESTSN 1140
Query: 3421 KYEELKQSFNTLFEKNEFTASSMQKVYADLTKLITESCGSAEMTSLEVENVAVFDPFRDG 3600
KYEELKQSFNTLFEKNEFTASSMQKVYADLTKLITESCGSAEMTSLEVENVAVFDPFRDG
Sbjct: 1141 KYEELKQSFNTLFEKNEFTASSMQKVYADLTKLITESCGSAEMTSLEVENVAVFDPFRDG 1200
Query: 3601 SFENLLEAVRKILSERLELQSVIDKLQSDLSSKSNDMEEMTQRSLDSTSXXXXXXXXXXX 3780
SFENLLEAVRKILSERLELQSVIDKLQSDLSSKSNDMEEMTQRSLDSTS
Sbjct: 1201 SFENLLEAVRKILSERLELQSVIDKLQSDLSSKSNDMEEMTQRSLDSTSLRELVEKVEGL 1260
Query: 3781 XXXXSGVIFESPSSQVEFLVSQLVQKFIEIEELANLLRKQLEAKGNELMEIEESLLHHKT 3960
SGVIFESPSSQVEFLVSQLVQKFIEIEELANLLRKQLEAKGNELMEIEESLLHHKT
Sbjct: 1261 LELESGVIFESPSSQVEFLVSQLVQKFIEIEELANLLRKQLEAKGNELMEIEESLLHHKT 1320
Query: 3961 KIAGLRESLTQAEESLVAVRSELQDKSNELEQSEQRLLSTREKLSIAVTKGKGLIVQRDN 4140
KIAGLRESLTQAEESLVAVRSELQDKSNELEQSEQRLLSTREKLSIAVTKGKGLIVQRDN
Sbjct: 1321 KIAGLRESLTQAEESLVAVRSELQDKSNELEQSEQRLLSTREKLSIAVTKGKGLIVQRDN 1380
Query: 4141 VKQSLAEASAKLQKCSEELNSKDARLVEVEKKLKTYIEAGERVEALESELSYIRNSATAL 4320
VKQSLAEASAKLQKCSEELNSKDARLVEVEKKLKTYIEAGERVEALESELSYIRNSATAL
Sbjct: 1381 VKQSLAEASAKLQKCSEELNSKDARLVEVEKKLKTYIEAGERVEALESELSYIRNSATAL 1440
Query: 4321 RESFLLKDSXXXXXXXXXXXXXXXXXFHARDILEKVEWLARSANGNSSRPSGWDQKSSDG 4500
RESFLLKDS FHARDILEKVEWLARSANGNSSRPSGWDQKSSDG
Sbjct: 1441 RESFLLKDSLLHRIEEILEDLDLPEHFHARDILEKVEWLARSANGNSSRPSGWDQKSSDG 1500
Query: 4501 GAGFVLSEPWREDVQTGTSSEDDLRIKFEELKGKFYGLAEQNEMLEQSLMERNTLVQRWE 4680
GAGFVLSEPWREDVQTGTSSEDDLRIKFEELKGKFYGLAEQNEMLEQSLMERNTLVQRWE
Sbjct: 1501 GAGFVLSEPWREDVQTGTSSEDDLRIKFEELKGKFYGLAEQNEMLEQSLMERNTLVQRWE 1560
Query: 4681 KLLENIDIPPQLHSMEVENKIEWLASTITEATHDRDNLQQKIDNLEVYCQSVTTDLEVSQ 4860
KLLENIDIPPQLHSMEVENKIEWLASTITEATHDRDNLQQKIDNLEVYCQSVTTDLEVSQ
Sbjct: 1561 KLLENIDIPPQLHSMEVENKIEWLASTITEATHDRDNLQQKIDNLEVYCQSVTTDLEVSQ 1620
Query: 4861 KQVGDVEGNLQSCVSERVNLSERLESLIGDHESLSARGIHLEVENEKLQNQVKDLHEKLV 5040
KQVGDVEGNLQSCVSERVNLSERLESLIGDHESLSARGIHLEVENEKLQNQVKDLHEKLV
Sbjct: 1621 KQVGDVEGNLQSCVSERVNLSERLESLIGDHESLSARGIHLEVENEKLQNQVKDLHEKLV 1680
Query: 5041 EKLGNEEHFQTIEGDLLSLRYMIDDVIQEDGLQDLALASNSENLDGVLRKLIDYYKNLVK 5220
EKLGNEEHFQTIEGDLLSLRYMIDDVIQEDGLQDLALASNSENLDGVLRKLIDYYKNLVK
Sbjct: 1681 EKLGNEEHFQTIEGDLLSLRYMIDDVIQEDGLQDLALASNSENLDGVLRKLIDYYKNLVK 1740
Query: 5221 SSLPGETDDNVCETRPSDADVRSGESLGAHGATSHGQHFELSDSNVVEATSRDIAVVETP 5400
SSLPGETDDNVCETRPSDADVRSGESLGAHGATSHGQHFELSDSNVVEATSRDIAVVETP
Sbjct: 1741 SSLPGETDDNVCETRPSDADVRSGESLGAHGATSHGQHFELSDSNVVEATSRDIAVVETP 1800
Query: 5401 DVASLTKDLDQALHVQKLTREERDLYMAKQQSLVAENEALDKKIIXXXXXXXXXXXXSAS 5580
DVASLTKDLDQALHVQKLTREERDLYMAKQQSLVAENEALDKKII SAS
Sbjct: 1801 DVASLTKDLDQALHVQKLTREERDLYMAKQQSLVAENEALDKKIIELQEFLKQEEQKSAS 1860
Query: 5581 VREKLNVAVRKGKALVQQRDSLKQTIEEVNAELGRLKSEIIKRDEKLLENEKKFRELESY 5760
VREKLNVAVRKGKALVQQRDSLKQTIEEVNAELGRLKSEIIKRDEKLLENEKKFRELESY
Sbjct: 1861 VREKLNVAVRKGKALVQQRDSLKQTIEEVNAELGRLKSEIIKRDEKLLENEKKFRELESY 1920
Query: 5761 SVRVESLESECQLLKIHSQETEYLLQERSGDINDPVMKLQRISQLFQTMSTTVTSAEQES 5940
SVRVESLESECQLLKIHSQETEYLLQERSGDINDPVMKLQRISQLFQTMSTTVTSAEQES
Sbjct: 1921 SVRVESLESECQLLKIHSQETEYLLQERSGDINDPVMKLQRISQLFQTMSTTVTSAEQES 1980
Query: 5941 RKSRRXXXXXXXXXXXVQETNDSLQEDLSKFTYEIQQLSRXXXXXXXXXXXXISRFENLS 6120
RKSRR VQETNDSLQEDLSKFTYEIQQLSR ISRFENLS
Sbjct: 1981 RKSRRAAELLLAELNEVQETNDSLQEDLSKFTYEIQQLSREKDAAEAAKVEAISRFENLS 2040
Query: 6121 AVSNEEKNKLYAQLLSCGTSVNSLRKILAGTNSCLADIFIMDMEFLHHLKANMELCAKKT 6300
AVSNEEKNKLYAQLLSCGTSVNSLRKILAGTNSCLADIFIMDMEFLHHLKANMELCAKKT
Sbjct: 2041 AVSNEEKNKLYAQLLSCGTSVNSLRKILAGTNSCLADIFIMDMEFLHHLKANMELCAKKT 2100
Query: 6301 GTDLSGLPQLSTENLVDKEIFARLSAAWSNINLHETSSGGNIAEICGSLSQNLDQFVVGV 6480
GTDLSGLPQLSTENLVDKEIFARLSAAWSNINLHETSSGGNIAEICGSLSQNLDQFVVGV
Sbjct: 2101 GTDLSGLPQLSTENLVDKEIFARLSAAWSNINLHETSSGGNIAEICGSLSQNLDQFVVGV 2160
Query: 6481 SHLEEKVSKHLATWHDQINIVSNSIDTFFKSIGTGTDSEVAALGERIALLHGACSSVLVE 6660
SHLEEKVSKHLATWHDQINIVSNSIDTFFKSIGTGTDSEVAALGERIALLHGACSSVLVE
Sbjct: 2161 SHLEEKVSKHLATWHDQINIVSNSIDTFFKSIGTGTDSEVAALGERIALLHGACSSVLVE 2220
Query: 6661 IERRKAELVGNDDFNMSLHQVDEDFSSMESVRSMVNRLSSAVKELVVANAETLERNEKEM 6840
IERRKAELVGNDDFNMSLHQVDEDFSSMESVRSMVNRLSSAVKELVVANAETLERNEKEM
Sbjct: 2221 IERRKAELVGNDDFNMSLHQVDEDFSSMESVRSMVNRLSSAVKELVVANAETLERNEKEM 2280
Query: 6841 KVIIANLQRELHEKDIQNNRTCNELVGQVKEAQAGAKIFAEDLQSASARMRDMQDQLGIL 7020
KVIIANLQRELHEKDIQNNRTCNELVGQVKEAQAGAKIFAEDLQSASARMRDMQDQLGIL
Sbjct: 2281 KVIIANLQRELHEKDIQNNRTCNELVGQVKEAQAGAKIFAEDLQSASARMRDMQDQLGIL 2340
Query: 7021 VRERDSMKERVKELLAGQASHSELQEKVTSLSDLLAAKDLEIEALMQALDEEESQMEDLK 7200
VRERDSMKERVKELLAGQASHSELQEKVTSLSDLLAAKDLEIEALMQALDEEESQMEDLK
Sbjct: 2341 VRERDSMKERVKELLAGQASHSELQEKVTSLSDLLAAKDLEIEALMQALDEEESQMEDLK 2400
Query: 7201 LRVTELEQEVQQKNLDLQKAEASRGKISKKLSITVDKFDELHHLSENLLAEIEKLQQQVQ 7380
LRVTELEQEVQQKNLDLQKAEASRGKISKKLSITVDKFDELHHLSENLLAEIEKLQQQVQ
Sbjct: 2401 LRVTELEQEVQQKNLDLQKAEASRGKISKKLSITVDKFDELHHLSENLLAEIEKLQQQVQ 2460
Query: 7381 DRDTEVSFLRQEVTRCTNEALAASQMGTKRDSEEIQTVLSWFDTIASLLGIEDSLSTDAD 7560
DRDTEVSFLRQEVTRCTNEALAASQMGTKRDSEEIQTVLSWFDTIASLLGIEDSLSTDAD
Sbjct: 2461 DRDTEVSFLRQEVTRCTNEALAASQMGTKRDSEEIQTVLSWFDTIASLLGIEDSLSTDAD 2520
Query: 7561 SHINHYMETFEKRIASMLSEIDELRLVGQSKDVLLEGERSRVAELRQKEATLEKFLLEKE 7740
SHINHYMETFEKRIASMLSEIDELRLVGQSKDVLLEGERSRVAELRQKEATLEKFLLEKE
Sbjct: 2521 SHINHYMETFEKRIASMLSEIDELRLVGQSKDVLLEGERSRVAELRQKEATLEKFLLEKE 2580
Query: 7741 SQQDXXXXXXXXXXXXXPLINKWTKTSIPSQVRSLRKGNMDQVAISIDADQTDQSGSLEE 7920
SQQD PLINKWTKTSIPSQVRSLRKGNMDQVAISIDADQTDQSGSLEE
Sbjct: 2581 SQQDISTSSTSEIVEVEPLINKWTKTSIPSQVRSLRKGNMDQVAISIDADQTDQSGSLEE 2640
Query: 7921 DDDKDHSLRQESFLDSQDPSLTWSMVYGQTLFIHGSRSVVSCDRTLMRQPALRLGIMLYW 8100
DDDKDHSLRQESFLDSQDPSLTWSMVYGQTLFIHGSRSVVSCDRTLMRQPALRLGIMLYW
Sbjct: 2641 DDDKDHSLRQESFLDSQDPSLTWSMVYGQTLFIHGSRSVVSCDRTLMRQPALRLGIMLYW 2700
Query: 8101 AILHALLAAFVV 8136
AILHALLAAFVV
Sbjct: 2701 AILHALLAAFVV 2712
>ref|NP_173855.1| unknown protein; protein id: At1g24460.1 [Arabidopsis thaliana]
Length = 1730
Score = 162 bits (410), Expect = 8e-38
Identities = 289/1511 (19%), Positives = 592/1511 (39%), Gaps = 143/1511 (9%)
Frame = +1
Query: 3901 LEAKGNELMEIE-------ESLLHHKTKIAGLRESLTQAEESLVAVRSELQDKSNELEQS 4059
L A +EL E++ E L H + + E + + +E ++R+E + ELE
Sbjct: 255 LGAACSELFELKQKEAAFFERLSHLEDENRNFVEQVNREKEMCESMRTEFEKLKAELELE 314
Query: 4060 EQRLLSTREKLSIAVTKGKGLIVQRDNVKQSLAEASAKLQKCSEELNSKDARLVEVEKKL 4239
+ + +T+EKLS+AVTKGK L+ RD +K L+E + +L EL K+ L E + +
Sbjct: 315 KTKCTNTKEKLSMAVTKGKALVQNRDALKHQLSEKTTELANRLTELQEKEIAL-ESSEVM 373
Query: 4240 KTYIEAG--ERVEALESELSYIRNSATALRESFLLKDSXXXXXXXXXXXXXXXXXFHARD 4413
K +E E+ + LE + + + + +L L K +
Sbjct: 374 KGQLEQSLTEKTDELEKCYAELNDRSVSLEAYELTKKELE------------------QS 415
Query: 4414 ILEKVEWLARSANGNSSRPSGWDQKSSDGGA---GFVLSEPWREDVQTGTSSEDDLRIKF 4584
+ EK + L + DQ D G + ++E + S +++
Sbjct: 416 LAEKTKELEECLTKLQEMSTALDQSELDKGELAKSDAMVASYQEMLSVRNSIIENIETIL 475
Query: 4585 EEL----KGKFYGLAEQNEMLEQSLMERNTLVQRWEKLLE---NIDIPPQLHSMEVENKI 4743
+ +G + + E+ L + E + Q + +L + +ID+P ++ +E+++
Sbjct: 476 SNIYTPEEGHSFDIVEKVRSLAEERKELTNVSQEYNRLKDLIVSIDLPEEMSQSSLESRL 535
Query: 4744 EWLASTITEATHDRDNLQQKIDNLEVYCQSVTTDLEVSQKQVGDVEGNLQSCVS------ 4905
WL + + + + LQ +I+++ + + + +K++ D+ +L+
Sbjct: 536 AWLRESFLQGKDEVNALQNRIESVSMSLSAEMEEKSNIRKELDDLSFSLKKMEETAERGS 595
Query: 4906 -ERVNLSERLESLIG-------DHESLSARGIHLEVEN--EKLQNQVKDLHEKLVEKLGN 5055
ER + RL G DH S I+L V+ +K++ Q++D + GN
Sbjct: 596 LEREEIVRRLVETSGLMTEGVEDHTSSD---INLLVDRSFDKIEKQIRDSSDS---SYGN 649
Query: 5056 EEHFQTIEGDLLSLRYMID-------DVIQEDGLQDLALASNSENLDGVLRKL--IDYYK 5208
EE F+ + SL Y+ D +++ E L +++ S+ L ++L + K
Sbjct: 650 EEIFEAFQ----SLLYVRDLEFSLCKEMLGEGELISFQVSNLSDELKIASQELAFVKEEK 705
Query: 5209 NLVKSSLPGETDDNVCETRPSDADVRSGESLGAHGATSHGQHFELSDSNVVEATSRDIAV 5388
++ L + + ++ G+ L + S + + +
Sbjct: 706 IALEKDLERSEEKSALLRDKLSMAIKKGKGL-VQDREKFKTQLDEKKSEIEKLMLELQQL 764
Query: 5389 VETPD-----VASLTKDLDQALHVQK---LTREERDLYMAKQQSLVAENEALDKKIIXXX 5544
T D + L++DL++ ++ T+EERD QQSL + L K +
Sbjct: 765 GGTVDGYKNQIDMLSRDLERTKELETELVATKEERDQL---QQSLSLIDTLLQKVMKSVE 821
Query: 5545 XXXXXXXXXSASVREKLNVAVRKGKALVQQRDSLKQTIEEVNAELGRLKSEIIKRDEKLL 5724
S EK++ + + R ++ IE+V +E+ L S++ + L
Sbjct: 822 IIALPVDLASEDPSEKIDRLAGYIQEVQLARVEEQEEIEKVKSEVDALTSKLAETQTALK 881
Query: 5725 ENEKKFRELESYSVRVESLESECQLLKIHSQETEYLLQERSGDINDPVMKLQRISQLFQT 5904
E E + L E + ++ + E LQ+ D + +L + T
Sbjct: 882 LVEDALSTAED---NISRLTEENRNVQAAKENAELELQKAVADASSVASELDEVLATKST 938
Query: 5905 MSTTV---------------------TSAEQESRKSRRXXXXXXXXXXXVQETNDSLQED 6021
+ + +AE E ++ T +SL+E
Sbjct: 939 LEAALMQAERNISDIISEKEEAQGRTATAEMEQEMLQKEASIQKNKLTEAHSTINSLEET 998
Query: 6022 LSKFTYEIQQLSRXXXXXXXXXXXXISRFENLSAVSNEEKNKLYAQLLSCGTSVNSLRK- 6198
L++ + LS+ + E L + E+NK+ L+ + +L K
Sbjct: 999 LAQTESNMDSLSKQIEDDKVLTTSLKNELEKLKIEAEFERNKMAEASLTIVSHEEALMKA 1058
Query: 6199 --------------------ILAGTNSCLADIF-------IMDMEFLHHLKANMELCAKK 6297
+ + N C+ ++ +E + HL N+++ K
Sbjct: 1059 ENSLSALQGEMVKAEGEISTLSSKLNVCMEELAGSSGNSQSKSLEIITHLD-NLQMLLKD 1117
Query: 6298 TG--TDLSGLPQLSTENLVDKEIFAR-----------LSAAWSNINLHETSSGGNIAEIC 6438
G + ++ Q ++L D ++ AR L+ N T + ++++
Sbjct: 1118 GGLISKVNEFLQRKFKSLRDVDVIARDITRNIGENGLLAGEMGNAEDDSTEAKSLLSDLD 1177
Query: 6439 GSLSQNLDQFVVGVSHLEEKVSKHLATWHDQINIVSNSIDTFFKSIGTGTDSEVAALGER 6618
S++ + G + E+++S L + + + + +++ F+ T D+ +A L +
Sbjct: 1178 NSVNTEPENSQ-GSAADEDEISSSLRKMAEGVRLRNKTLENNFEGFSTSIDTLIATLMQN 1236
Query: 6619 IALLHGACSSVL-----VEIERRKAELVGNDDFNMSLHQVDEDFSSMESVRSMVNR-LSS 6780
+ +++ +E + R E + + N ++ + +D SS+ S R L
Sbjct: 1237 MTAARADVLNIVGHNSSLEEQVRSVENIVREQEN-TISALQKDLSSLISACGAAARELQL 1295
Query: 6781 AVKELVVANAETLERNEKEMKVIIANLQRELHEKDIQNNRTCNELVGQVKEAQAGAKIFA 6960
VK ++ + + NE ++ +ELH + EL ++A A K+F
Sbjct: 1296 EVKNNLLELVQ-FQENENGGEMESTEDPQELHVSECAQR--IKELSSAAEKACATLKLFE 1352
Query: 6961 EDLQSASARMRDMQDQLGIL-------VRERDSMKERVKELLAGQASHSELQEKVTSLSD 7119
+A+ +RDM+++L V ERD + +V A + E + ++++L D
Sbjct: 1353 TTNNAAATVIRDMENRLTEASVALEKAVLERDLNQTKVSSSEAKEEKWHEKEVELSTLYD 1412
Query: 7120 LLAAKDLEI-EALMQALDEEESQMEDLKLRVTELEQEVQQKNLDLQKAEASRGKIS-KKL 7293
L ++ E E L+ A D M L ++ +E ++DL + KKL
Sbjct: 1413 KLLVQEQEAKENLIPASD-----MRTLFDKINGIEVP----SVDLVNGLDPQSPYDVKKL 1463
Query: 7294 SITVDKFDELHHLSENLLAEIEKLQQQVQDRDTEVSFLRQEVTRCTNEALAASQMGTKRD 7473
VD E+ H + L ++L + ++D E+ L++ EA + +++ +
Sbjct: 1464 FAIVDSVTEMQHQIDILSYGQKELNSTLAEKDLEIQGLKK-----ATEAESTTELELVKA 1518
Query: 7474 SEEIQTVLSWFDTIASLLGIEDSLSTDADSHINHYMETFEKRIASMLSEIDELRLVGQSK 7653
E+ ++S + + +L + + S ++ EK+I S+L E + + Q
Sbjct: 1519 KNELSKLISGLEKLLGILASNNPVVDPNFSESWTLVQALEKKITSLLLESESSKSRAQEL 1578
Query: 7654 DVLLEGERSRVAELRQKEATLEKFLLEKESQQDXXXXXXXXXXXXXPLINKWTK------ 7815
+ L G V +L + E+ L K Q D P ++ ++
Sbjct: 1579 GLKLAGSEKLVDKLSLRVKEFEEKLQTKAIQPDIVQERSIFETPRAPSTSEISEIEDKGA 1638
Query: 7816 ------TSIPS--QVRSLRKGNMDQVAISIDADQTDQSGSLEEDDDKDHSLRQESFLDSQ 7971
+ +P+ QVR++RKG+ D ++I+ID++ + E D+DK +
Sbjct: 1639 LGIKSISPVPTAAQVRTVRKGSTDHLSINIDSESEHLMNNNETDEDKGQDSGGLRWKSID 1698
Query: 7972 DPSLTWSMVYG 8004
+PS + + YG
Sbjct: 1699 EPSSSKAWRYG 1709
Score = 101 bits (251), Expect = 2e-19
Identities = 172/819 (21%), Positives = 303/819 (36%), Gaps = 49/819 (5%)
Frame = +1
Query: 3013 DSLKLRNDNISVENTELNKKLNYCS---LRIDXXXXXXXXXXXXXTSFLSTMEEQLVALQ 3183
D+LK +S + TEL +L + ++ T +E+ L
Sbjct: 340 DALK---HQLSEKTTELANRLTELQEKEIALESSEVMKGQLEQSLTEKTDELEKCYAELN 396
Query: 3184 DESERAMMVEHELTSLMSEFGEAVVRLDDCLLRSGTSGAHTGLDMTKRISGSV------- 3342
D S E L E L++CL + T LD ++ G +
Sbjct: 397 DRSVSLEAYELTKKELEQSLAEKTKELEECLTK--LQEMSTALDQSELDKGELAKSDAMV 454
Query: 3343 -------DVAVNVIEDLKEKLEAAYVKHESTSNKYEELKQSFNTLFEKNEFTASSMQKVY 3501
V ++IE+++ L Y E S E +S E+ E T S + Y
Sbjct: 455 ASYQEMLSVRNSIIENIETILSNIYTPEEGHSFDIVEKVRSLAE--ERKELTNVSQE--Y 510
Query: 3502 ADLTKLITESCGSAEMT--SLEVENVAVFDPFRDG-----SFENLLEAVRKILSERLELQ 3660
L LI EM+ SLE + + F G + +N +E+V LS +E +
Sbjct: 511 NRLKDLIVSIDLPEEMSQSSLESRLAWLRESFLQGKDEVNALQNRIESVSMSLSAEMEEK 570
Query: 3661 SVIDKLQSDLSSKSNDMEEMTQRSLDSTSXXXXXXXXXXXXXXXSGVIFESPSSQVEFLV 3840
S I K DLS MEE +R SG++ E +
Sbjct: 571 SNIRKELDDLSFSLKKMEETAERG------SLEREEIVRRLVETSGLMTEGVEDHTSSDI 624
Query: 3841 SQLVQKFIEIEELANLLRKQLEAK-GNE-LMEIEESLLHHKT------------------ 3960
+ LV + +++ +R ++ GNE + E +SLL+ +
Sbjct: 625 NLLVDR--SFDKIEKQIRDSSDSSYGNEEIFEAFQSLLYVRDLEFSLCKEMLGEGELISF 682
Query: 3961 KIAGLRESLTQAEESLVAVRSELQDKSNELEQSEQRLLSTREKLSIAVTKGKGLIVQRDN 4140
+++ L + L A + L V+ E +LE+SE++ R+KLS+A+ KGKGL+ R+
Sbjct: 683 QVSNLSDELKIASQELAFVKEEKIALEKDLERSEEKSALLRDKLSMAIKKGKGLVQDREK 742
Query: 4141 VKQSLAEASAKLQKCSEELNSKDARLVEVEKKLKTYIEAGERVEALESELSYIRNSATAL 4320
K L E ++++K EL + + ++ ER + LE+EL + L
Sbjct: 743 FKTQLDEKKSEIEKLMLELQQLGGTVDGYKNQIDMLSRDLERTKELETELVATKEERDQL 802
Query: 4321 RESFLLKDSXXXXXXXXXXXXXXXXXFHARDILEKVEWLARSANGNSSRPSGWDQKSSDG 4500
++S L D+ + +++ VE +A + S PS + D
Sbjct: 803 QQSLSLIDTL------------------LQKVMKSVEIIALPVDLASEDPS----EKIDR 840
Query: 4501 GAGFVLSEPWREDVQTGTSSEDDLRIKFEELKGKFYGLAEQNEMLEQSLMERNTLVQRWE 4680
AG++ ++VQ E + + E++K + + L L E T ++
Sbjct: 841 LAGYI------QEVQLARVEEQE---EIEKVKSEV-------DALTSKLAETQTALKL-- 882
Query: 4681 KLLENIDIPPQLHSMEVENKIEWLASTITEATHDRDNLQQKIDNLEVYCQSVTTDLEVSQ 4860
VE+ + I+ T + N+Q +N E+ Q D
Sbjct: 883 ----------------VEDALSTAEDNISRLTEENRNVQAAKENAELELQKAVADASSVA 926
Query: 4861 KQVGDVEGNLQSCVSERVNLSERLESLIGDHESLSARGIHLEVENEKLQNQVKDLHEKLV 5040
++ +V + + + + +I + E R E+E E LQ + KL
Sbjct: 927 SELDEVLATKSTLEAALMQAERNISDIISEKEEAQGRTATAEMEQEMLQKEASIQKNKLT 986
Query: 5041 EKLGN----EEHFQTIEGDLLSLRYMIDDVIQEDGLQDLALASNSENLDGVLRKLIDYYK 5208
E EE E ++ SL I+D D L ++ +N L+ ++ +
Sbjct: 987 EAHSTINSLEETLAQTESNMDSLSKQIED--------DKVLTTSLKNELEKLKIEAEFER 1038
Query: 5209 N-LVKSSLPGETDDNVCETRPSDADVRSGESLGAHGATS 5322
N + ++SL + + + GE + A G S
Sbjct: 1039 NKMAEASLTIVSHEEALMKAENSLSALQGEMVKAEGEIS 1077
Score = 62.0 bits (149), Expect = 1e-07
Identities = 243/1231 (19%), Positives = 459/1231 (36%), Gaps = 79/1231 (6%)
Frame = +1
Query: 865 SVAFDTVELEGINGNFRSQQIR-EAAELNEEKPETSIDFPNNRDHVLSAEPEESSVAEMA 1041
S+ T ELE + + EA EL +++ E S+ + +E S A
Sbjct: 380 SLTEKTDELEKCYAELNDRSVSLEAYELTKKELEQSLAEKTKELEECLTKLQEMSTALDQ 439
Query: 1042 SQLQLPE-SVSISGVLSHEETRKI-DTLNLSAELTSAHVHEGRSVSFLQLMDIVKGLGQD 1215
S+L E + S + V S++E + +++ + E ++++ +++ V+ L ++
Sbjct: 440 SELDKGELAKSDAMVASYQEMLSVRNSIIENIETILSNIYTPEEGHSFDIVEKVRSLAEE 499
Query: 1216 EYQILCNAREAASSTEPGTSSLERLREELFVSSTMEDILHVQLTEQSHLQIEFDHQHNQF 1395
+ L N + + + S++ L EE+ SS + ++ +S LQ + + N
Sbjct: 500 RKE-LTNVSQEYNRLKDLIVSID-LPEEMSQSSLESRLAWLR---ESFLQGK--DEVNAL 552
Query: 1396 VAEISQLRASYSAVTERNDSLAEELSECQSKL--YAATSSNTNLENQL----------LA 1539
I + S SA E ++ +EL + L T+ +LE + L
Sbjct: 553 QNRIESVSMSLSAEMEEKSNIRKELDDLSFSLKKMEETAERGSLEREEIVRRLVETSGLM 612
Query: 1540 TEAQVEDFTA------------KMNXXXXXXXXXXXXXXXXXXXFINLQVENDTLVAVIS 1683
TE VED T+ K+ F +L D ++
Sbjct: 613 TEG-VEDHTSSDINLLVDRSFDKIEKQIRDSSDSSYGNEEIFEAFQSLLYVRDLEFSLCK 671
Query: 1684 SMNDXXXXXXXXXXXXNYEIKHLSSELCNCKNLAAILKAEVEQFENTIGPLTDEKIHLVE 1863
M + E+K S EL K L+ ++E+ E L D+ ++
Sbjct: 672 EMLGEGELISFQVSNLSDELKIASQELAFVKEEKIALEKDLERSEEKSALLRDKLSMAIK 731
Query: 1864 EKYSLLGEAEKLQEELANCKTVVTLQEVENSNMKETLSLLTRQQTMFEENNIHLREENEK 2043
+ L+ + EK + +L K+ + +E + T+ +N I + + +
Sbjct: 732 KGKGLVQDREKFKTQLDEKKSEIEKLMLELQQLGGTVDGY--------KNQIDMLSRDLE 783
Query: 2044 AHLELSAHLISETYLLSEYSNLKEGYTLLNNKLLKFQGEKEHLV--------EENDKLTQ 2199
EL L++ E L++ +L++ L K E + + ++K+ +
Sbjct: 784 RTKELETELVATK---EERDQLQQSLSLIDTLLQKVMKSVEIIALPVDLASEDPSEKIDR 840
Query: 2200 ELLTLQEHMSTVEEERTHLEVELREAIARLDKLAEENTSLTSSIMVEKARMVDNGSADVS 2379
+QE EE+ +E E A KLAE T+L +VE A + ++S
Sbjct: 841 LAGYIQEVQLARVEEQEEIEKVKSEVDALTSKLAETQTALK---LVEDA--LSTAEDNIS 895
Query: 2380 GLINQEISEKLGR-SSEIGVSKQSASFLENTQYTNLEEVREYTSEFSALMKNLEKG-EKM 2553
L + + + + ++E+ + K A ++ + L+EV S A + E+ +
Sbjct: 896 RLTEENRNVQAAKENAELELQKAVAD--ASSVASELDEVLATKSTLEAALMQAERNISDI 953
Query: 2554 VQNLEEAIKQILTDSSVSKSSDKGATPAVSKLIQAFXXXXXXXXXXXXNAQLTDDLS--- 2724
+ EEA + T + K A+ +KL +A D LS
Sbjct: 954 ISEKEEAQGRTATAEMEQEMLQKEASIQKNKLTEAHSTINSLEETLAQTESNMDSLSKQI 1013
Query: 2725 EADQFVSVNV--QIRNXXXXXXXXXXNARKAGIQFNQLNDDRTSTNQRLEELNVEFASHQ 2898
E D+ ++ ++ ++ +A + + L L E +
Sbjct: 1014 EDDKVLTTSLKNELEKLKIEAEFERNKMAEASLTIVSHEEALMKAENSLSALQGEMVKAE 1073
Query: 2899 DHINVLEADTIESKVSFEALKHYSYELQHKNHDLELLCDSLKLRNDN---ISVENTELNK 3069
I+ L + + V E L S Q K+ ++ D+L++ + IS N L +
Sbjct: 1074 GEISTLSS---KLNVCMEELAGSSGNSQSKSLEIITHLDNLQMLLKDGGLISKVNEFLQR 1130
Query: 3070 KLNYCSLR------------------IDXXXXXXXXXXXXXTSFLSTMEEQLVALQDESE 3195
K + SLR + S LS ++ + + S+
Sbjct: 1131 K--FKSLRDVDVIARDITRNIGENGLLAGEMGNAEDDSTEAKSLLSDLDNSVNTEPENSQ 1188
Query: 3196 RAMMVEHELTSLMSEFGEAVVRLDDCLLRSGTSGAHTGLDMTKRISGSVDVAVNVIEDLK 3375
+ E E++S + + E VRL + L + G T +D +I L
Sbjct: 1189 GSAADEDEISSSLRKMAEG-VRLRNKTLENNFEGFSTSID-------------TLIATLM 1234
Query: 3376 EKLEAA------YVKHESTSNKYEELKQSFNTLFEKNEFTASSMQKVYADLTKLITESCG 3537
+ + AA V H S+ EE +S + + E T S++QK DL+ LI+
Sbjct: 1235 QNMTAARADVLNIVGHNSS---LEEQVRSVENIVREQENTISALQK---DLSSLISACGA 1288
Query: 3538 SAEMTSLEVENVAVFDPFRDGSFENLLEAVRKILSER-LELQSVIDKLQSDLSSKSNDME 3714
+A LEV+N NLLE V+ +E E++S D + +S + ++
Sbjct: 1289 AARELQLEVKN-------------NLLELVQFQENENGGEMESTEDPQELHVSECAQRIK 1335
Query: 3715 EMTQRSLDSTSXXXXXXXXXXXXXXXSGVIFESPSSQVEFLVSQLVQKFIEIE---ELAN 3885
E++ + + + +FE+ ++ ++ + + E E A
Sbjct: 1336 ELSSAAEKACATLK---------------LFETTNNAAATVIRDMENRLTEASVALEKAV 1380
Query: 3886 LLRKQLEAKGNELMEIEESLLHHKTKIAGLRESL----TQAEESLVAVRS--ELQDKSNE 4047
L R + K + EE + +++ L + L +A+E+L+ L DK N
Sbjct: 1381 LERDLNQTKVSSSEAKEEKWHEKEVELSTLYDKLLVQEQEAKENLIPASDMRTLFDKING 1440
Query: 4048 LEQSEQRLLSTREKLSIAVTKGKGLIVQRDNVKQSLAEASAKLQKCSEELNSKDARLVEV 4227
+E L++ + S K IV Q + + QK ELNS L E
Sbjct: 1441 IEVPSVDLVNGLDPQSPYDVKKLFAIVDSVTEMQHQIDILSYGQK---ELNS---TLAEK 1494
Query: 4228 EKKLKTYIEAGERVEALESELSYIRNSATAL 4320
+ +++ +A E E EL +N + L
Sbjct: 1495 DLEIQGLKKATEAESTTELELVKAKNELSKL 1525
>gb|AAF97958.1|AC000103_8 F21J9.12 [Arabidopsis thaliana]|gi|25403244|pir||F86378 protein
F21J9.12 [imported] - Arabidopsis thaliana
Length = 1864
Score = 149 bits (375), Expect = 9e-34
Identities = 298/1564 (19%), Positives = 595/1564 (37%), Gaps = 207/1564 (13%)
Frame = +1
Query: 3901 LEAKGNELMEIE-------ESLLHHKTKIAGLRESLTQAEESLVAVRSELQDKSNELEQS 4059
L A +EL E++ E L H + + E + + +E ++R+E + ELE
Sbjct: 285 LGAACSELFELKQKEAAFFERLSHLEDENRNFVEQVNREKEMCESMRTEFEKLKAELELE 344
Query: 4060 EQRLLSTREKLSIAVTKGKGLIVQRDNVKQSLAEASAKLQKCSEELNSKDARLVEVEKKL 4239
+ + +T+EKLS+AVTKGK L+ RD +K L+E + +L EL K+ L E + +
Sbjct: 345 KTKCTNTKEKLSMAVTKGKALVQNRDALKHQLSEKTTELANRLTELQEKEIAL-ESSEVM 403
Query: 4240 KTYIEAG--ERVEALESELSYIRNSATALRESFLLKDSXXXXXXXXXXXXXXXXXFHARD 4413
K +E E+ + LE + + + + +L L K +
Sbjct: 404 KGQLEQSLTEKTDELEKCYAELNDRSVSLEAYELTKKELE------------------QS 445
Query: 4414 ILEKVEWLARSANGNSSRPSGWDQKSSDGGA---GFVLSEPWREDVQTGTSSEDDLRIKF 4584
+ EK + L + DQ D G + ++E + S +++
Sbjct: 446 LAEKTKELEECLTKLQEMSTALDQSELDKGELAKSDAMVASYQEMLSVRNSIIENIETIL 505
Query: 4585 EEL----KGKFYGLAEQNEMLEQSLMERNTLVQRWEKLLE---NIDIPPQLHSMEVENKI 4743
+ +G + + E+ L + E + Q + +L + +ID+P ++ +E+++
Sbjct: 506 SNIYTPEEGHSFDIVEKVRSLAEERKELTNVSQEYNRLKDLIVSIDLPEEMSQSSLESRL 565
Query: 4744 EWLASTITEATHDRDNLQQKIDNLEVYCQSVTTDLEVSQKQVGDVEGNLQSCVS------ 4905
WL + + + + LQ +I+++ + + + +K++ D+ +L+
Sbjct: 566 AWLRESFLQGKDEVNALQNRIESVSMSLSAEMEEKSNIRKELDDLSFSLKKMEETAERGS 625
Query: 4906 -ERVNLSERLESLIG-------DHESLSARGIHLEVEN--EKLQNQVKDLHEKLVEKLGN 5055
ER + RL G DH S I+L V+ +K++ Q++D + GN
Sbjct: 626 LEREEIVRRLVETSGLMTEGVEDHTSSD---INLLVDRSFDKIEKQIRDSSDS---SYGN 679
Query: 5056 EEHFQTIEGDLLSLRYMID-------DVIQEDGLQDLALASNSENLDGVLRKL--IDYYK 5208
EE F+ + SL Y+ D +++ E L +++ S+ L ++L + K
Sbjct: 680 EEIFEAFQ----SLLYVRDLEFSLCKEMLGEGELISFQVSNLSDELKIASQELAFVKEEK 735
Query: 5209 NLVKSSLPGETDDNVCETRPSDADVRSGESLGAHGATSHGQHFELSDSNVVEATSRDIAV 5388
++ L + + ++ G+ L + S + + +
Sbjct: 736 IALEKDLERSEEKSALLRDKLSMAIKKGKGL-VQDREKFKTQLDEKKSEIEKLMLELQQL 794
Query: 5389 VETPD-----VASLTKDLDQALHVQK---LTREERDLYMAKQQSLVAENEALDKKIIXXX 5544
T D + L++DL++ ++ T+EERD QQSL + L K +
Sbjct: 795 GGTVDGYKNQIDMLSRDLERTKELETELVATKEERDQL---QQSLSLIDTLLQKVMKSVE 851
Query: 5545 XXXXXXXXXSASVREKLNVAVRKGKALVQQRDSLKQTIEEVNAELGRLKSEIIKRDEKLL 5724
S EK++ + + R ++ IE+V +E+ L S++ + L
Sbjct: 852 IIALPVDLASEDPSEKIDRLAGYIQEVQLARVEEQEEIEKVKSEVDALTSKLAETQTALK 911
Query: 5725 ENEKKFRELESYSVRVESLESECQLLKIHSQETEYLLQERSGDINDPVMKLQRISQLFQT 5904
E E + L E + ++ + E LQ+ D + +L + T
Sbjct: 912 LVEDALSTAED---NISRLTEENRNVQAAKENAELELQKAVADASSVASELDEVLATKST 968
Query: 5905 MSTTV---------------------TSAEQESRKSRRXXXXXXXXXXXVQETNDSLQED 6021
+ + +AE E ++ T +SL+E
Sbjct: 969 LEAALMQAERNISDIISEKEEAQGRTATAEMEQEMLQKEASIQKNKLTEAHSTINSLEET 1028
Query: 6022 LSKFTYEIQQLSRXXXXXXXXXXXXISRFENLSAVSNEEKNKLYAQLLSCGTSVNSLRK- 6198
L++ + LS+ + E L + E+NK+ L+ + +L K
Sbjct: 1029 LAQTESNMDSLSKQIEDDKVLTTSLKNELEKLKIEAEFERNKMAEASLTIVSHEEALMKA 1088
Query: 6199 --------------------ILAGTNSCLADIF-------IMDMEFLHHLKANMELCAKK 6297
+ + N C+ ++ +E + HL N+++ K
Sbjct: 1089 ENSLSALQGEMVKAEGEISTLSSKLNVCMEELAGSSGNSQSKSLEIITHLD-NLQMLLKD 1147
Query: 6298 TG--TDLSGLPQLSTENLVDKEIFARLSAAWSNINLHETSSG--GNIAEI---------- 6435
G + ++ Q ++L D ++ AR NI + +G GN +
Sbjct: 1148 GGLISKVNEFLQRKFKSLRDVDVIAR--DITRNIGENGLLAGEMGNAEAVLLITLLYFQD 1205
Query: 6436 ----CGSLSQNLDQFV-------VGVSHLEEKVSKHLATWHDQINIVSNSIDTFFKSIGT 6582
SL +LD V G + E+++S L + + + + +++ F+ T
Sbjct: 1206 DSTEAKSLLSDLDNSVNTEPENSQGSAADEDEISSSLRKMAEGVRLRNKTLENNFEGFST 1265
Query: 6583 GTDSEVAALGERIALLHGACSSVL-----VEIERRKAELVGNDDFNMSLHQVDEDFSSME 6747
D+ +A L + + +++ +E + R E + + N ++ + +D SS+
Sbjct: 1266 SIDTLIATLMQNMTAARADVLNIVGHNSSLEEQVRSVENIVREQEN-TISALQKDLSSLI 1324
Query: 6748 SVRSMVNR-LSSAVKELVVANAETLERNEKEMKVIIANLQRELHEKDIQNNRTCNELVGQ 6924
S R L VK ++ + + NE ++ +ELH + EL
Sbjct: 1325 SACGAAARELQLEVKNNLLELVQ-FQENENGGEMESTEDPQELHVSECAQR--IKELSSA 1381
Query: 6925 VKEAQAGAKIFAEDLQSASARMRDMQDQLGILVRERDSMKERVKELLAGQASHSELQEKV 7104
++A A K+F +A+ +RDM+++L ++++ V E Q S + KV
Sbjct: 1382 AEKACATLKLFETTNNAAATVIRDMENRL---TEASVALEKAVLERDLNQTKVSSSEAKV 1438
Query: 7105 TSLSDLLAAKDLEIEALMQALDEEESQMEDLKLRVTELEQEVQQKN-------------- 7242
SL +L L++E L + EE+ ++++L + VQ++
Sbjct: 1439 ESLEELCQDLKLQLENLR--VKEEKWHEKEVELSTLYDKLLVQEQGNFYLLLSLISLNLH 1496
Query: 7243 -----------LDLQKAEASRGKIS---------------------------------KK 7290
L L+ AEA I KK
Sbjct: 1497 HIITTILKCHVLLLRIAEAKENLIPASDMRTLFDKINGIEVPSVDLVNGLDPQSPYDVKK 1556
Query: 7291 LSITVDKFDELHHLSENLLAEIEKLQQQVQDRDTEVSFLRQEVTRCTNEALAASQMGTKR 7470
L VD E+ H + L ++L + ++D E+ L++ EA + +++ +
Sbjct: 1557 LFAIVDSVTEMQHQIDILSYGQKELNSTLAEKDLEIQGLKK-----ATEAESTTELELVK 1611
Query: 7471 DSEEIQTVLSWFDTIASLLGIEDSLSTDADSHINHYMETFEKRIASMLSEIDELRLVGQS 7650
E+ ++S + + +L + + S ++ EK+I S+L E + + Q
Sbjct: 1612 AKNELSKLISGLEKLLGILASNNPVVDPNFSESWTLVQALEKKITSLLLESESSKSRAQE 1671
Query: 7651 KDVLLEGERSRVAELRQKEATLEKFLLEKESQQDXXXXXXXXXXXXXPLINKWTK----- 7815
+ L G V +L + E+ L K Q D P ++ ++
Sbjct: 1672 LGLKLAGSEKLVDKLSLRVKEFEEKLQTKAIQPDIVQERSIFETPRAPSTSEISEIEDKG 1731
Query: 7816 -------TSIPS--QVRSLRKGNMDQVAISIDADQTDQSGSLEEDDDKDH---SLRQESF 7959
+ +P+ QVR++RKG+ D ++I+ID++ + E D+DK H SL
Sbjct: 1732 ALGIKSISPVPTAAQVRTVRKGSTDHLSINIDSESEHLMNNNETDEDKGHVFKSLNMSGL 1791
Query: 7960 LDSQ 7971
+ +Q
Sbjct: 1792 IPTQ 1795
Score = 101 bits (251), Expect = 2e-19
Identities = 172/819 (21%), Positives = 303/819 (36%), Gaps = 49/819 (5%)
Frame = +1
Query: 3013 DSLKLRNDNISVENTELNKKLNYCS---LRIDXXXXXXXXXXXXXTSFLSTMEEQLVALQ 3183
D+LK +S + TEL +L + ++ T +E+ L
Sbjct: 370 DALK---HQLSEKTTELANRLTELQEKEIALESSEVMKGQLEQSLTEKTDELEKCYAELN 426
Query: 3184 DESERAMMVEHELTSLMSEFGEAVVRLDDCLLRSGTSGAHTGLDMTKRISGSV------- 3342
D S E L E L++CL + T LD ++ G +
Sbjct: 427 DRSVSLEAYELTKKELEQSLAEKTKELEECLTK--LQEMSTALDQSELDKGELAKSDAMV 484
Query: 3343 -------DVAVNVIEDLKEKLEAAYVKHESTSNKYEELKQSFNTLFEKNEFTASSMQKVY 3501
V ++IE+++ L Y E S E +S E+ E T S + Y
Sbjct: 485 ASYQEMLSVRNSIIENIETILSNIYTPEEGHSFDIVEKVRSLAE--ERKELTNVSQE--Y 540
Query: 3502 ADLTKLITESCGSAEMT--SLEVENVAVFDPFRDG-----SFENLLEAVRKILSERLELQ 3660
L LI EM+ SLE + + F G + +N +E+V LS +E +
Sbjct: 541 NRLKDLIVSIDLPEEMSQSSLESRLAWLRESFLQGKDEVNALQNRIESVSMSLSAEMEEK 600
Query: 3661 SVIDKLQSDLSSKSNDMEEMTQRSLDSTSXXXXXXXXXXXXXXXSGVIFESPSSQVEFLV 3840
S I K DLS MEE +R SG++ E +
Sbjct: 601 SNIRKELDDLSFSLKKMEETAERG------SLEREEIVRRLVETSGLMTEGVEDHTSSDI 654
Query: 3841 SQLVQKFIEIEELANLLRKQLEAK-GNE-LMEIEESLLHHKT------------------ 3960
+ LV + +++ +R ++ GNE + E +SLL+ +
Sbjct: 655 NLLVDR--SFDKIEKQIRDSSDSSYGNEEIFEAFQSLLYVRDLEFSLCKEMLGEGELISF 712
Query: 3961 KIAGLRESLTQAEESLVAVRSELQDKSNELEQSEQRLLSTREKLSIAVTKGKGLIVQRDN 4140
+++ L + L A + L V+ E +LE+SE++ R+KLS+A+ KGKGL+ R+
Sbjct: 713 QVSNLSDELKIASQELAFVKEEKIALEKDLERSEEKSALLRDKLSMAIKKGKGLVQDREK 772
Query: 4141 VKQSLAEASAKLQKCSEELNSKDARLVEVEKKLKTYIEAGERVEALESELSYIRNSATAL 4320
K L E ++++K EL + + ++ ER + LE+EL + L
Sbjct: 773 FKTQLDEKKSEIEKLMLELQQLGGTVDGYKNQIDMLSRDLERTKELETELVATKEERDQL 832
Query: 4321 RESFLLKDSXXXXXXXXXXXXXXXXXFHARDILEKVEWLARSANGNSSRPSGWDQKSSDG 4500
++S L D+ + +++ VE +A + S PS + D
Sbjct: 833 QQSLSLIDTL------------------LQKVMKSVEIIALPVDLASEDPS----EKIDR 870
Query: 4501 GAGFVLSEPWREDVQTGTSSEDDLRIKFEELKGKFYGLAEQNEMLEQSLMERNTLVQRWE 4680
AG++ ++VQ E + + E++K + + L L E T ++
Sbjct: 871 LAGYI------QEVQLARVEEQE---EIEKVKSEV-------DALTSKLAETQTALKL-- 912
Query: 4681 KLLENIDIPPQLHSMEVENKIEWLASTITEATHDRDNLQQKIDNLEVYCQSVTTDLEVSQ 4860
VE+ + I+ T + N+Q +N E+ Q D
Sbjct: 913 ----------------VEDALSTAEDNISRLTEENRNVQAAKENAELELQKAVADASSVA 956
Query: 4861 KQVGDVEGNLQSCVSERVNLSERLESLIGDHESLSARGIHLEVENEKLQNQVKDLHEKLV 5040
++ +V + + + + +I + E R E+E E LQ + KL
Sbjct: 957 SELDEVLATKSTLEAALMQAERNISDIISEKEEAQGRTATAEMEQEMLQKEASIQKNKLT 1016
Query: 5041 EKLGN----EEHFQTIEGDLLSLRYMIDDVIQEDGLQDLALASNSENLDGVLRKLIDYYK 5208
E EE E ++ SL I+D D L ++ +N L+ ++ +
Sbjct: 1017 EAHSTINSLEETLAQTESNMDSLSKQIED--------DKVLTTSLKNELEKLKIEAEFER 1068
Query: 5209 N-LVKSSLPGETDDNVCETRPSDADVRSGESLGAHGATS 5322
N + ++SL + + + GE + A G S
Sbjct: 1069 NKMAEASLTIVSHEEALMKAENSLSALQGEMVKAEGEIS 1107
Score = 57.4 bits (137), Expect = 4e-06
Identities = 230/1185 (19%), Positives = 442/1185 (36%), Gaps = 84/1185 (7%)
Frame = +1
Query: 865 SVAFDTVELEGINGNFRSQQIR-EAAELNEEKPETSIDFPNNRDHVLSAEPEESSVAEMA 1041
S+ T ELE + + EA EL +++ E S+ + +E S A
Sbjct: 410 SLTEKTDELEKCYAELNDRSVSLEAYELTKKELEQSLAEKTKELEECLTKLQEMSTALDQ 469
Query: 1042 SQLQLPE-SVSISGVLSHEETRKI-DTLNLSAELTSAHVHEGRSVSFLQLMDIVKGLGQD 1215
S+L E + S + V S++E + +++ + E ++++ +++ V+ L ++
Sbjct: 470 SELDKGELAKSDAMVASYQEMLSVRNSIIENIETILSNIYTPEEGHSFDIVEKVRSLAEE 529
Query: 1216 EYQILCNAREAASSTEPGTSSLERLREELFVSSTMEDILHVQLTEQSHLQIEFDHQHNQF 1395
+ L N + + + S++ L EE+ SS + ++ +S LQ + + N
Sbjct: 530 RKE-LTNVSQEYNRLKDLIVSID-LPEEMSQSSLESRLAWLR---ESFLQGK--DEVNAL 582
Query: 1396 VAEISQLRASYSAVTERNDSLAEELSECQSKL--YAATSSNTNLENQL----------LA 1539
I + S SA E ++ +EL + L T+ +LE + L
Sbjct: 583 QNRIESVSMSLSAEMEEKSNIRKELDDLSFSLKKMEETAERGSLEREEIVRRLVETSGLM 642
Query: 1540 TEAQVEDFTA------------KMNXXXXXXXXXXXXXXXXXXXFINLQVENDTLVAVIS 1683
TE VED T+ K+ F +L D ++
Sbjct: 643 TEG-VEDHTSSDINLLVDRSFDKIEKQIRDSSDSSYGNEEIFEAFQSLLYVRDLEFSLCK 701
Query: 1684 SMNDXXXXXXXXXXXXNYEIKHLSSELCNCKNLAAILKAEVEQFENTIGPLTDEKIHLVE 1863
M + E+K S EL K L+ ++E+ E L D+ ++
Sbjct: 702 EMLGEGELISFQVSNLSDELKIASQELAFVKEEKIALEKDLERSEEKSALLRDKLSMAIK 761
Query: 1864 EKYSLLGEAEKLQEELANCKTVVTLQEVENSNMKETLSLLTRQQTMFEENNIHLREENEK 2043
+ L+ + EK + +L K+ + +E + T+ +N I + + +
Sbjct: 762 KGKGLVQDREKFKTQLDEKKSEIEKLMLELQQLGGTVDGY--------KNQIDMLSRDLE 813
Query: 2044 AHLELSAHLISETYLLSEYSNLKEGYTLLNNKLLKFQGEKEHLV--------EENDKLTQ 2199
EL L++ E L++ +L++ L K E + + ++K+ +
Sbjct: 814 RTKELETELVATK---EERDQLQQSLSLIDTLLQKVMKSVEIIALPVDLASEDPSEKIDR 870
Query: 2200 ELLTLQEHMSTVEEERTHLEVELREAIARLDKLAEENTSL------------TSSIMVEK 2343
+QE EE+ +E E A KLAE T+L S + E+
Sbjct: 871 LAGYIQEVQLARVEEQEEIEKVKSEVDALTSKLAETQTALKLVEDALSTAEDNISRLTEE 930
Query: 2344 ARMVDNGSADVSGLINQEISEKLGRSSEIGVSKQSASFLE-------------------- 2463
R V + + + +++ +SE+ + S LE
Sbjct: 931 NRNVQAAKENAELELQKAVADASSVASELDEVLATKSTLEAALMQAERNISDIISEKEEA 990
Query: 2464 NTQYTNLEEVREYTSEFSALMKN-LEKGEKMVQNLEEAIKQILTD-SSVSK--SSDKGAT 2631
+ E +E + +++ KN L + + +LEE + Q ++ S+SK DK T
Sbjct: 991 QGRTATAEMEQEMLQKEASIQKNKLTEAHSTINSLEETLAQTESNMDSLSKQIEDDKVLT 1050
Query: 2632 PAVSKLIQAFXXXXXXXXXXXXNAQLTDDLSEADQFVSVNVQIRNXXXXXXXXXXNARKA 2811
++ ++ A LT +S + + +
Sbjct: 1051 TSLKNELEKLKIEAEFERNKMAEASLT-IVSHEEALMKAENSLSALQGEMVKAEGEISTL 1109
Query: 2812 GIQFNQLNDDRTSTNQRLEELNVEFASHQDHINVLEAD-TIESKVSFEALKHYSYELQHK 2988
+ N ++ ++ + ++E +H D++ +L D + SKV+ E L+ L+
Sbjct: 1110 SSKLNVCMEELAGSSGNSQSKSLEIITHLDNLQMLLKDGGLISKVN-EFLQRKFKSLR-- 1166
Query: 2989 NHDLELLCDSLKLRNDNISVENTELNKKLNYCSLRIDXXXXXXXXXXXXXTSFLSTMEEQ 3168
D++++ + NI EN L ++ + S LS ++
Sbjct: 1167 --DVDVIARDI---TRNIG-ENGLLAGEMGNAEAVLLITLLYFQDDSTEAKSLLSDLDNS 1220
Query: 3169 LVALQDESERAMMVEHELTSLMSEFGEAVVRLDDCLLRSGTSGAHTGLDMTKRISGSVDV 3348
+ + S+ + E E++S + + E VRL + L + G T +D
Sbjct: 1221 VNTEPENSQGSAADEDEISSSLRKMAEG-VRLRNKTLENNFEGFSTSID----------- 1268
Query: 3349 AVNVIEDLKEKLEAA------YVKHESTSNKYEELKQSFNTLFEKNEFTASSMQKVYADL 3510
+I L + + AA V H S+ EE +S + + E T S++QK DL
Sbjct: 1269 --TLIATLMQNMTAARADVLNIVGHNSS---LEEQVRSVENIVREQENTISALQK---DL 1320
Query: 3511 TKLITESCGSAEMTSLEVENVAVFDPFRDGSFENLLEAVRKILSER-LELQSVIDKLQSD 3687
+ LI+ +A LEV+N NLLE V+ +E E++S D +
Sbjct: 1321 SSLISACGAAARELQLEVKN-------------NLLELVQFQENENGGEMESTEDPQELH 1367
Query: 3688 LSSKSNDMEEMTQRSLDSTSXXXXXXXXXXXXXXXSGVIFESPSSQVEFLVSQLVQKFIE 3867
+S + ++E++ + + + VI + + E S ++K +
Sbjct: 1368 VSECAQRIKELSSAAEKACATLKLFETTNNAAAT---VIRDMENRLTE--ASVALEKAVL 1422
Query: 3868 IEELANLLRKQLEAKGNELMEIEESLLHHKTKIAGLRESLTQAEESLVAVRSELQDKSNE 4047
+L EAK L E+ + L K ++ LR + E V + S L DK
Sbjct: 1423 ERDLNQTKVSSSEAKVESLEELCQDL---KLQLENLRVKEEKWHEKEVEL-STLYDKLLV 1478
Query: 4048 LEQSEQRLLSTREKLSI-----AVTKGKGLIVQRDNVKQSLAEAS 4167
EQ LL + L++ + K L+++ K++L AS
Sbjct: 1479 QEQGNFYLLLSLISLNLHHIITTILKCHVLLLRIAEAKENLIPAS 1523
>gb|AAC60300.1| kinesin-related protein [Xenopus laevis]|gi|7512169|pir||T14156
kinesin-related protein - African clawed frog
Length = 2954
Score = 126 bits (317), Expect = 5e-27
Identities = 373/2026 (18%), Positives = 773/2026 (37%), Gaps = 110/2026 (5%)
Frame = +1
Query: 1891 EKLQEELANCKTVVTLQEVENSNMKETLSLLTRQQTMFEENNIHLREENEKAHLELSAHL 2070
++LQ + K +V E++ + ++E LS+ + M + RE + A ++
Sbjct: 560 QQLQSKEEEKKELVQSFELKIAELEEQLSVKAKNLEMVTNS----REHSINAEVQTD--- 612
Query: 2071 ISETYLLSEYSNLKE-GYTLLNNKLLKFQGEKEHLVEENDKLTQELLTLQEHMSTVEEER 2247
+ + + E S L + GY N+ L + + L +D+ EH +E++
Sbjct: 613 VEKEVVRKEMSVLGDSGYNASNSDLQDSSVDGKRLSSSHDECI-------EHRKMLEQKI 665
Query: 2248 THLEVELREAIARLDKLAE------------ENTSLTSSIMVEKAR-------MVDNGSA 2370
V+L E I L+K +E E+ L +IM EKA M DN
Sbjct: 666 ----VDLEEFIENLNKKSENDKQKSSEQDFMESIQLCEAIMAEKANALEELALMRDNFDN 721
Query: 2371 DV--SGLINQEISEKLGRSSEIGVSKQSASFLENTQYTNLEEVREYTSEFSALMKNLEKG 2544
+ + + +EI++ L RS + LE T E + E +L K +E
Sbjct: 722 IILENETLKREIAD-LERSLKENQETNEFEILEKE--TQKEHEAQLIHEIGSLKKLVENA 778
Query: 2545 EKMVQNLEEAIK---QILTDSSVSKSSDKGATPAVSKLIQAFXXXXXXXXXXXXNAQLTD 2715
E QNLEE ++ ++L + + + + + K ++ F L+
Sbjct: 779 EMYNQNLEEDLETKTKLLKEQEIQLAELRKRADNLQKKVRNF--------------DLSV 824
Query: 2716 DLSEADQFVSVNVQIRNXXXXXXXXXXNARKAGIQFNQLNDDRTSTNQRLEELNVEFASH 2895
+ ++++ Q++ +A+K + + L + +++E+ + +
Sbjct: 825 SMGDSEKLCEEIFQLKQSLSDAEAVTRDAQK---ECSFLRSENLELKEKMEDTSNWYNQK 881
Query: 2896 QDHINVLEADTIESKVSFEALK-HYSYELQHKNHDLELLCDSLKLRNDNISVENTELNKK 3072
+ ++ E K +++ ++ ELQ +++ L L + + EL KK
Sbjct: 882 EKAASLFEKQLETEKSNYKKMEADLQKELQSAFNEINYLNGLLAGKVPRDLLSRVELEKK 941
Query: 3073 LNYCSLRIDXXXXXXXXXXXXXTSFLSTMEEQLVALQDESERAMMVEHELTSLMSEFGEA 3252
++ S +++ + +E ++ L + + +E+ L ++ +A
Sbjct: 942 VSEFSKQLEKALEEK-----------NALENEVTCLSEYK----FLPNEVECLKNQISKA 986
Query: 3253 VVRLDDCLLRSGTSGAHTGLDMTKRISGSVDVAVNVIEDLKEKLEAAYVKHESTSNKYEE 3432
+ LL+ G H+ ++K+ + + +++ L +++ K + T +Y E
Sbjct: 987 SEEI--MLLKQ--EGEHSASIISKQEIIMQEQSEQILQ-LTDEVTHTQSKVQQTEEQYLE 1041
Query: 3433 LKQSFNTLFEKNEFTASSMQKVYADLTKLITESCGSAEMTSLEVENVAVFDPFRDGSFEN 3612
+K+ + LFEK S + + ++ L M S+EV
Sbjct: 1042 MKKMHDDLFEKYIRNKSEAEDLLREMENL------KGTMESVEV---------------- 1079
Query: 3613 LLEAVRKILSERLELQSVIDKLQSDLSSKSNDMEEMTQRSLDSTSXXXXXXXXXXXXXXX 3792
KI + EL+ I + L K + M Q T
Sbjct: 1080 ------KIADTKHELEETIRDKEQLLHEKKYFFQAM-QTIFPITPLSDSLPPSKLVEGNS 1132
Query: 3793 SGVIFESPSSQVEFLVSQLVQKFIEIEELANLLRKQLEAKGNELMEIEESLLHHKTKIAG 3972
I + + L ++ + +E N L++Q+ +L ++ + K+ +
Sbjct: 1133 QDPIEINDYHNLIALATERNNIMVCLETERNSLKEQVIDLNTQLQSLQAQSIE-KSDLQK 1191
Query: 3973 LRESLTQAEESLVA----VRSELQDKSNELEQSEQRLLSTREKLSIAVTKGKGLIVQRDN 4140
++ L + E L+ ++ L D +E+ + L EKL + K + ++R+
Sbjct: 1192 PKQDLEEGEVKLLLEMELLKGHLTDSQLSIEKLQLENLEVTEKLQTLQEEMKNITIERNE 1251
Query: 4141 VKQSLAEASAKLQKCSEELNSKDARLVEVEKKLKTYIEAGERVEALESELSYIRNSATAL 4320
++ + + A+ ++L+ + +E + +L+ A + EL + +
Sbjct: 1252 LQTNFEDLKAEHDSLKQDLSENIEQSIETQDELR----------AAQEELREQKQLVDSF 1301
Query: 4321 RESFLLKDSXXXXXXXXXXXXXXXXXFHARDILEKVEWLARSANGNSSRPSGWDQKSSDG 4500
R+ L D + A N +K S G
Sbjct: 1302 RQQLL-------------------------DCSVGISSPNHDAVANQ-------EKVSLG 1329
Query: 4501 GAGFVLSEPWR---EDVQTG----TSSEDDLRIKFEELKGKFYGLAEQNEMLEQSLMERN 4659
+ SE R +++QT S + LR + ++G+ + ++ LE+ ++ ++
Sbjct: 1330 EVNSLQSEMLRGERDELQTSCKALVSELELLRAHVKSVEGENLEITKKLNGLEKEILGKS 1389
Query: 4660 TLVQRWEKLLENIDIPPQLHSMEVENKIEWLASTITEATHDRDNLQQKIDNLEVYCQSVT 4839
+ + +LEN+ E NK++ A E ++N Q ++ + Q +
Sbjct: 1390 EESEVLKSMLENLK--------EDNNKLKEQA----EEYSSKEN-QFSLEEVFSGSQKLV 1436
Query: 4840 TDLEVSQKQVGDVEGNLQS--------CVSERVNLSE-RLES-LIGDHE--SLSARGIHL 4983
++EV + Q+ E L+ + NL E +LE+ L DHE S+ R +
Sbjct: 1437 DEIEVLKAQLKAAEERLEIKDRDYFELVQTANTNLVEGKLETPLQADHEEDSIDRRSEEM 1496
Query: 4984 EVE--NEKLQNQVKDLHEKLVEKLGNEEHFQTIEGDLLSLRYMIDDVIQEDGLQDLALAS 5157
E++ EKL+ L EKL + ++ ++ + + DD+ Q+ L+ L L+
Sbjct: 1497 EIKVLGEKLERNQYLLERLQEEKLELSNKLEILQKEMETSVLLKDDLQQK--LESL-LSE 1553
Query: 5158 N---SENLDGVLRKLIDYYKNLVKSSLPGETDDNVCETRPSDADVRSGESLGAHGATSHG 5328
N EN+D L+ D L K+ + N+ + + +
Sbjct: 1554 NIILKENIDTTLKHHSDTQAQLQKTQQELQLAKNLAIAASDNCPITQEKE---------- 1603
Query: 5329 QHFELSDSNVVEATSRDIAVVETPDVASLTKDLDQALHVQ-KLTREERDLYMAKQQSLVA 5505
TS D + LT++L Q + Q KL E+ +L A Q L
Sbjct: 1604 -------------TSADCVHPLEEKILLLTEELHQKTNEQEKLLHEKNELEQA-QVELKC 1649
Query: 5506 ENEALDKKIIXXXXXXXXXXXXSASVREKLNVAVRKGKALVQQRDSLKQTIEEVNAELGR 5685
E E L K +I ++L ++ + + Q++ L+QT E + AE+
Sbjct: 1650 EVEHLMKSMIESKSSLESLQHEKHDTEQQLLALKQQMQVVTQEKKELQQTHEHLTAEVDH 1709
Query: 5686 LKSEI-----IKRD-------EKLLENEKKFRELESYSVRVESLESECQLLKIHSQETEY 5829
LK I K + E+ L NE K E + ++ E +E + LK E
Sbjct: 1710 LKENIELGLNFKNEAQQKTTKEQCLLNENKELEQSQHRLQCE-IEELMKSLKDKESALET 1768
Query: 5830 LLQERSGDIN---DPVMKLQRISQLFQTMSTTVTSAEQESRKSRRXXXXXXXXXXXVQET 6000
L + IN + M + + +L + T + +Q R +++
Sbjct: 1769 LKESEQKVINLNQEMEMVMLEMEELKNSQRTVIAERDQLQDDLRESVEMSIETQDDLRKA 1828
Query: 6001 NDSLQEDLSK---FTYEIQQLSRXXXXXXXXXXXXISRF-ENLSAVS--NEEKNKLYAQL 6162
++LQ+ K T +I L ++ E LS N+ K L++++
Sbjct: 1829 QEALQQQKDKVQELTSQISVLQEKISLLENQMLYNVATVKETLSERDDLNQSKQHLFSEI 1888
Query: 6163 LSCGTSVNSLRKILAGTNSCLADIFIMDMEFLHHLKANMELCAKKTGTDLSGLPQLSTEN 6342
+ S+ L AD ++ + +N+E + T+L E
Sbjct: 1889 ETLSLSLKEKEFALEQAEKDKADAARKTIDITEKI-SNIEEQLLQQATNLK-------ET 1940
Query: 6343 LVDKE--IFARLSAAWSNINLHETSSGGNIAEICGSLSQNLDQFVVGVSHLEEKVSKHLA 6516
L ++E I + A + +L ET ++A G + Q D+ V L EK+S
Sbjct: 1941 LYERESLIQCKEQLALNTEHLRETLKSKDLA--LGKMEQERDEAANKVIALTEKMS---- 1994
Query: 6517 TWHDQINIVSNSIDTFFKSIGTGTDSEVAALGERIALLHGACSSVLVEIERRKAELVGND 6696
+ +QIN ++ T + G E L + ++E + L D
Sbjct: 1995 SLEEQIN---ENVTTLKEGEGEK---------ETFYLQRPSKQQSSSQMEELRESLKTKD 2042
Query: 6697 DFNMSLHQVDEDFS-SMESVRSMVNRLSSAVKELV---------VANAETLERNEKEMKV 6846
+ L + +++ S + ++++ ++SS +E++ V+ E L +++++
Sbjct: 2043 ---LQLEEAEKEISEATNEIKNLTAKISSLEEEILQNASILNEAVSERENLRHSKQQLVS 2099
Query: 6847 IIANLQRELHEKD---IQNNRTCNELVGQVKEAQAGAKIFAEDLQSASARMRDMQDQLGI 7017
+ L L +D Q+ R +E V ++ KI +++ +Q+Q
Sbjct: 2100 ELEQLSLTLKSRDHAFAQSKREKDEAVNKIASLAEEIKILTKEMDEFRDSKESLQEQSSH 2159
Query: 7018 LVRERDSMKERVKELLAGQAS-HSELQEKVTSLSDLLAAKDLEIEALMQALDEEESQMED 7194
L E + K ++ L + +++L EKV + +LL + +L + LD+ + ++ +
Sbjct: 2160 LSEELCTYKTELQMLKQQKEDINNKLAEKVKEVDELLQ----HLSSLKEQLDQIQMELRN 2215
Query: 7195 LKLRVTEL-------EQEVQQKNLDLQKAEASRGKISKKLSITVDKFDELHHLSENLLAE 7353
KLR EL E+E+ L + + +++++ I + E+ L E + A
Sbjct: 2216 EKLRNYELCEKMDIMEKEISVLRLMQNEPQQEEDDVAERMDILESRNQEIQELMEKISAV 2275
Query: 7354 I-----------EKLQQQVQDRDTEVSFLRQEVTRCTNEALAASQMGTKRDSEEIQTVLS 7500
+LQ++ + + +++ ++ + + + Q + + ++QT+L+
Sbjct: 2276 YSEQHTLLSSLSSELQKETEAHKHCMLNIKESLSSTLSRSFGSLQTEHVKLNTQLQTLLN 2335
Query: 7501 WFDTIASLLGIEDSLSTDADSHINHYMETFEKRIASMLSEIDELRL 7638
F + +++ S D +EK +A+ DELRL
Sbjct: 2336 KFKVVYRTAAVKEDHSLIKD---------YEKDLAAEQKRHDELRL 2372
Score = 120 bits (301), Expect = 4e-25
Identities = 430/2336 (18%), Positives = 888/2336 (37%), Gaps = 110/2336 (4%)
Frame = +1
Query: 721 EMQEEDMEQFSELSAKAGVDKIATEERQTSYPAVVDSSASPSHFSEGSSVAFDT------ 882
E++ ++E+ +LS KA ++ T R+ S A V + + SV D+
Sbjct: 577 ELKIAELEE--QLSVKAKNLEMVTNSREHSINAEVQTDVEKEVVRKEMSVLGDSGYNASN 634
Query: 883 --VELEGINGNFRSQQIREAAELNEEKPETSIDFPNNRDHVLSAEPEESSVAEMASQLQL 1056
++ ++G S E E + + +D + + + + + + +S+
Sbjct: 635 SDLQDSSVDGKRLSSSHDECIEHRKMLEQKIVDL---EEFIENLNKKSENDKQKSSEQDF 691
Query: 1057 PESVSISGVLSHEETRKIDTLNLSAELTSAHVHEGRSVSFLQLMDIVKGLGQD----EYQ 1224
ES+ + + E+ ++ L L + + E ++ ++ D+ + L ++ E++
Sbjct: 692 MESIQLCEAIMAEKANALEELALMRDNFDNIILENETLK-REIADLERSLKENQETNEFE 750
Query: 1225 ILCNA--REAASSTEPGTSSLERLRE--ELFVSSTMEDI-LHVQLTEQSHLQI-EFDHQH 1386
IL +E + SL++L E E++ + ED+ +L ++ +Q+ E +
Sbjct: 751 ILEKETQKEHEAQLIHEIGSLKKLVENAEMYNQNLEEDLETKTKLLKEQEIQLAELRKRA 810
Query: 1387 NQFVAEISQLRASYSA-----VTERNDSLAEELSECQSKLYAATSSNTNLENQLLATEAQ 1551
+ ++ S S + E L + LS+ ++ A + L ++ L + +
Sbjct: 811 DNLQKKVRNFDLSVSMGDSEKLCEEIFQLKQSLSDAEAVTRDAQKECSFLRSENLELKEK 870
Query: 1552 VEDFTAKMNXXXXXXXXXXXXXXXXXXXF----INLQVENDTLVAVISSMNDXXXXXXXX 1719
+ED + N + +LQ E + I+ +N
Sbjct: 871 MEDTSNWYNQKEKAASLFEKQLETEKSNYKKMEADLQKELQSAFNEINYLNGLLAGKVPR 930
Query: 1720 XXXXNYEIKHLSSELCNCKNLAAILKAEVEQFENTIGPLTDEKIHLVEEKYSLLGEAEKL 1899
E++ SE K L L+ E EN + L++ K L E L + K
Sbjct: 931 DLLSRVELEKKVSEFS--KQLEKALE-EKNALENEVTCLSEYKF-LPNEVECLKNQISKA 986
Query: 1900 QEELANCKTVVTLQEVENSNMKETLSLLTRQQTMFEENNIHLRE-ENEKAHLELSAHLIS 2076
EE+ K QE E+S S++++Q+ + +E + + + +E H +
Sbjct: 987 SEEIMLLK-----QEGEHS-----ASIISKQEIIMQEQSEQILQLTDEVTHTQSKVQQTE 1036
Query: 2077 ETYLLSEYSNLKEGYTLLNNKLLKFQGEKEHLVEENDKLTQELLTLQEHMSTVEEERTHL 2256
E YL +K+ + L K ++ + E E L+ E + L + M +VE +
Sbjct: 1037 EQYL-----EMKKMHDDLFEKYIRNKSEAEDLLREMENL-------KGTMESVEVKIADT 1084
Query: 2257 EVELREAIARLDKLAEEN-------------TSLTSSIMVEKARMVDNGSAD-------- 2373
+ EL E I ++L E T L+ S+ K +V+ S D
Sbjct: 1085 KHELEETIRDKEQLLHEKKYFFQAMQTIFPITPLSDSLPPSK--LVEGNSQDPIEINDYH 1142
Query: 2374 -VSGLINQEISEKLGRSSEIGVSKQSASFLENTQYTNLEEVREYTSEFSALMKNLEKGEK 2550
+ L + + + +E K+ L NTQ +L+ S+ ++LE+GE
Sbjct: 1143 NLIALATERNNIMVCLETERNSLKEQVIDL-NTQLQSLQAQSIEKSDLQKPKQDLEEGEV 1201
Query: 2551 MVQNLEEAIKQILTDSSVSKSSDKGATPAVSKLIQAFXXXXXXXXXXXXNAQLTDDLSEA 2730
+ E +K LTDS +S + V++ +Q Q + +A
Sbjct: 1202 KLLLEMELLKGHLTDSQLSIEKLQLENLEVTEKLQTLQEEMKNITIERNELQTNFEDLKA 1261
Query: 2731 DQFVSVNVQIRNXXXXXXXXXXNARKAGIQFNQLNDDRTSTNQRLEELNVEFAS------ 2892
+ S+ + R A + + S Q+L + +V +S
Sbjct: 1262 EH-DSLKQDLSENIEQSIETQDELRAAQEELREQKQLVDSFRQQLLDCSVGISSPNHDAV 1320
Query: 2893 -HQDHINVLEADTIESKVSFEALKHYSYELQHKNHDLELLCDSLKLRNDNISVENTELNK 3069
+Q+ +++ E ++++S E L+ ELQ L + L+ ++ EN E+ K
Sbjct: 1321 ANQEKVSLGEVNSLQS----EMLRGERDELQTSCKALVSELELLRAHVKSVEGENLEITK 1376
Query: 3070 KLNYCSLRIDXXXXXXXXXXXXXTSFLSTMEEQLVALQDESERAMMVEHELTSLMSEFGE 3249
KLN ++ S L ++E L++++E E++ SL F
Sbjct: 1377 KLN----GLEKEILGKSEESEVLKSMLENLKEDNNKLKEQAEEYSSKENQF-SLEEVFSG 1431
Query: 3250 AVVRLDDC-LLRSGTSGAHTGLDMTKRISGSV--DVAVNVIEDLKEKLEAAYVKHESTSN 3420
+ +D+ +L++ A L++ R + N++E E A + +S
Sbjct: 1432 SQKLVDEIEVLKAQLKAAEERLEIKDRDYFELVQTANTNLVEGKLETPLQADHEEDSIDR 1491
Query: 3421 KYEELK-QSFNTLFEKNEFTASSMQKVYADLTKLITESCGSAEMTSLEVENVAVFDPFRD 3597
+ EE++ + E+N++ +Q+ +L+ + E+ E+E +
Sbjct: 1492 RSEEMEIKVLGEKLERNQYLLERLQEEKLELSNKL-------EILQKEMETSVLLK---- 1540
Query: 3598 GSFENLLEAVRKILSERLELQSVID---KLQSDLSSKSNDMEEMTQRSLDSTSXXXXXXX 3768
++L + + +LSE + L+ ID K SD ++ ++ Q + + +
Sbjct: 1541 ---DDLQQKLESLLSENIILKENIDTTLKHHSDTQAQLQKTQQELQLA-KNLAIAASDNC 1596
Query: 3769 XXXXXXXXSGVIFESPSSQVEFLVSQLVQKFIEIEELAN----LLRKQLEAKGNELMEIE 3936
S ++ L +L QK E E+L + L + Q+E K E+ +
Sbjct: 1597 PITQEKETSADCVHPLEEKILLLTEELHQKTNEQEKLLHEKNELEQAQVELK-CEVEHLM 1655
Query: 3937 ESLLHHKTKIAGLRESLTQAEESLVAVRSELQ---DKSNELEQSEQRL------------ 4071
+S++ K+ + L+ E+ L+A++ ++Q + EL+Q+ + L
Sbjct: 1656 KSMIESKSSLESLQHEKHDTEQQLLALKQQMQVVTQEKKELQQTHEHLTAEVDHLKENIE 1715
Query: 4072 --LSTREKLSIAVTKGKGLIVQRDNVKQSLAEASAKLQKCSEELNSKDARLVEVEKKLKT 4245
L+ + + TK + L+ + ++QS ++++ + L K++ L +++ +
Sbjct: 1716 LGLNFKNEAQQKTTKEQCLLNENKELEQSQHRLQCEIEELMKSLKDKESALETLKESEQK 1775
Query: 4246 YIEAGERVEALESELSYIRNS-ATALRESFLLKDSXXXXXXXXXXXXXXXXXFHARDILE 4422
I + +E + E+ ++NS T + E L+D R E
Sbjct: 1776 VINLNQEMEMVMLEMEELKNSQRTVIAERDQLQDDLRESVEMSIETQD-----DLRKAQE 1830
Query: 4423 KVEWLARSANGNSSRPSGWDQKSSDGGAGFVLSEPWREDVQT---GTSSEDDLRIK---- 4581
++ +S+ S +K S +L +V T S DDL
Sbjct: 1831 ALQQQKDKVQELTSQISVLQEKIS------LLENQMLYNVATVKETLSERDDLNQSKQHL 1884
Query: 4582 FEELKGKFYGLAEQNEMLEQSLMERNTLVQRWEKLLENIDIPPQLHSMEVENKIEWLAST 4761
F E++ L E+ LEQ+ ++ ++ + E I +E ++ A+
Sbjct: 1885 FSEIETLSLSLKEKEFALEQAEKDKADAARKTIDITEKIS--------NIEEQLLQQATN 1936
Query: 4762 ITEATHDRDNLQQKIDNLEVYCQSVTTDLEVSQKQVGDVEGNLQSCVSERVNLSERLESL 4941
+ E ++R++L Q + L + + + L+ +G +E ++ + L+E++ SL
Sbjct: 1937 LKETLYERESLIQCKEQLALNTEHLRETLKSKDLALGKMEQERDEAANKVIALTEKMSSL 1996
Query: 4942 ---IGDHESLSARGIHLEVENEKLQNQVKDLHEKLVEKLGNEEHFQTIEGDLLSLRYMID 5112
I ++ + G E E LQ K +E+L E +T
Sbjct: 1997 EEQINENVTTLKEG-EGEKETFYLQRPSKQQSSSQMEEL--RESLKT------------K 2041
Query: 5113 DVIQEDGLQDLALASNS-ENLDGVLRKLIDYYKNLVKSSLPGETDDNVCETRPSDADVRS 5289
D+ E+ ++++ A+N +NL + L + + L +S+ E R S + S
Sbjct: 2042 DLQLEEAEKEISEATNEIKNLTAKISSLEE--EILQNASILNEAVSERENLRHSKQQLVS 2099
Query: 5290 GESLGAHGATSHGQHFELSDSNVVEATSRDIAVVETPDVASLTKDLDQALHVQKLTREER 5469
+ S F S EA ++ +ASL +++ K+ +E
Sbjct: 2100 ELEQLSLTLKSRDHAFAQSKREKDEAVNK---------IASLAEEI-------KILTKEM 2143
Query: 5470 DLYMAKQQSLVAENEALDKKIIXXXXXXXXXXXXSASVREKLNVAVRKGKALVQQRDSLK 5649
D + ++SL ++ L +++ + KL V++ L+Q SLK
Sbjct: 2144 DEFRDSKESLQEQSSHLSEELCTYKTELQMLKQQKEDINNKLAEKVKEVDELLQHLSSLK 2203
Query: 5650 QTIEEVNAELGRLKSEIIKRDEKLLENE--KKFRELESYSVRVESLESECQLLKIHSQET 5823
+ ++++ EL R+EKL E +K +E + +++E Q + E
Sbjct: 2204 EQLDQIQMEL---------RNEKLRNYELCEKMDIMEKEISVLRLMQNEPQQEEDDVAER 2254
Query: 5824 EYLLQERSGDINDPVMKLQRISQLFQTMSTTVTSAEQESRKSRR--XXXXXXXXXXXVQE 5997
+L+ R+ +I + + K+ + T+ ++++S Q+ ++ + +
Sbjct: 2255 MDILESRNQEIQELMEKISAVYSEQHTLLSSLSSELQKETEAHKHCMLNIKESLSSTLSR 2314
Query: 5998 TNDSLQEDLSKFTYEIQQLSR-----XXXXXXXXXXXXISRFENLSAVSNEEKNKLYAQL 6162
+ SLQ + K ++Q L I +E A + ++L QL
Sbjct: 2315 SFGSLQTEHVKLNTQLQTLLNKFKVVYRTAAVKEDHSLIKDYEKDLAAEQKRHDELRLQL 2374
Query: 6163 LSCGTSVNSLRKILAGTNSCLADIFIMDMEFLHHLKANMELCAKKTGTDLSGLPQLSTEN 6342
++S ++ ++EFL+ EL KK + + Q ++
Sbjct: 2375 QCLEQHGRK------WSDSASEELKFCEIEFLN------ELLFKK-----ANIIQSVQDD 2417
Query: 6343 LVDKEIFARLSAAWSNINLHETSSGGNIAEICGSLSQNLDQFVVGVSHLEEKVSKHLATW 6522
+ ++F + ++ +L + L+ + LEE H+
Sbjct: 2418 FSEVQVF--------------------LNQVGSTLQEELEHKKGFMQWLEEFGDLHVDA- 2456
Query: 6523 HDQINIVSNSIDTFFKSIGTGTDSEVAALGERIALLHGACSSVLVEIERRKAELVGNDDF 6702
K + G E + I LL +V+ +R+ + N F
Sbjct: 2457 ---------------KKLSEGMQQENRRIASTIQLLTKRLKAVVQSKIQREITVYLN-QF 2500
Query: 6703 NMSLHQVDEDFSSMESVRSMVNRLSSAVKELVVANAETLERNEKEMKVIIANLQRELHEK 6882
L + E + E +R M + S A +E + I+ +Q E
Sbjct: 2501 EAKLQEKKE--QNKELMRRMEHHGPS---------ASVMEEENARLLGILKTVQDE---- 2545
Query: 6883 DIQNNRTCNELVGQVKEAQAGAKIFAEDLQSASARMRDMQDQLGILVRERDSMKERVKEL 7062
+L ++K + + +D ++ +QD+L L R
Sbjct: 2546 -------SKKLQSRIKMLENELNLVKDDAMHKGEKVAILQDKL--LSRN----------- 2585
Query: 7063 LAGQASHSELQEKVTSLSDLLAAKDLEIEALMQALDE----EESQMEDLKLRVTELEQEV 7230
+A + +Q K+T D L A EIE L + + + + ++++LK +V ++E E
Sbjct: 2586 --AEAELNAMQVKLTKKQDNLQAAMKEIENLQKMVAKGAVPYKEEIDNLKTKVVKIEME- 2642
Query: 7231 QQKNLDLQKAEASRGKISKKLSITVDKFDELHHLSENLLAEIEKLQQQVQDRDTEV 7398
++ ++A+ +I+ S DK + L L E+L++ D DT V
Sbjct: 2643 -----KIKYSKATDQEIAYLKSCLEDKEEGLRRLK-------EELRRAQADNDTTV 2686
Score = 105 bits (261), Expect = 2e-20
Identities = 335/1775 (18%), Positives = 677/1775 (37%), Gaps = 151/1775 (8%)
Frame = +1
Query: 2881 EFASHQDHINVLEADTIESKVSFEA-LKHYSYELQHKNHDLELLCDSLKLRNDNISVE-N 3054
E S Q + E + E SFE + +L K +LE++ +S R +I+ E
Sbjct: 554 EITSLQQQLQSKEEEKKELVQSFELKIAELEEQLSVKAKNLEMVTNS---REHSINAEVQ 610
Query: 3055 TELNKKLNYCSLRIDXXXXXXXXXXXXXTSFLSTMEEQLVALQDES-ERAMMVEHELTSL 3231
T++ K++ + + S S ++L + DE E M+E ++ L
Sbjct: 611 TDVEKEVVRKEMSVLGDSGYNASNSDLQDS--SVDGKRLSSSHDECIEHRKMLEQKIVDL 668
Query: 3232 MSEFGEAVVRLDDCLLRSGTSGAHTGLDMTKRISGSVDVAVNVIEDLKEKLEAAYVKHES 3411
+ ++ +S + + + I A+ + +++ + +++E+
Sbjct: 669 EEFIENLNKKSENDKQKSSEQDFMESIQLCEAIMAEKANALEELALMRDNFDNIILENET 728
Query: 3412 TSNKYEELKQSFNTLFEKNEFTASSMQKVYADLTKLITESCGSAEMTSLEVENVAVFDPF 3591
+ +L++S E NEF + +LI E GS + VEN +++
Sbjct: 729 LKREIADLERSLKENQETNEFEILEKETQKEHEAQLIHE-IGSLKKL---VENAEMYNQ- 783
Query: 3592 RDGSFENLLEAVRKILSER----LELQSVIDKLQS-----DLSSKSNDMEEMTQRSLDST 3744
+ E LE K+L E+ EL+ D LQ DLS D E++ +
Sbjct: 784 ---NLEEDLETKTKLLKEQEIQLAELRKRADNLQKKVRNFDLSVSMGDSEKLCEEIFQLK 840
Query: 3745 SXXXXXXXXXXXXXXXSGVIFESPSSQVEFLVSQLVQKFIEIEELANLLRKQLEAKGNEL 3924
+ S + +++ + + + E+ A+L KQLE + +
Sbjct: 841 QSLSDAEAVTRDAQKECSFL-RSENLELKEKMEDTSNWYNQKEKAASLFEKQLETEKSNY 899
Query: 3925 MEIEESLLHHK----TKIAGLRESLTQAEESLVAVRSELQDKSNELEQSEQRLLSTREKL 4092
++E L +I L L + R EL+ K +E + ++ L + L
Sbjct: 900 KKMEADLQKELQSAFNEINYLNGLLAGKVPRDLLSRVELEKKVSEFSKQLEKALEEKNAL 959
Query: 4093 SIAVT---KGKGLIVQRDNVKQSLAEASAKL---------------------QKCSEELN 4200
VT + K L + + +K +++AS ++ Q+ SE++
Sbjct: 960 ENEVTCLSEYKFLPNEVECLKNQISKASEEIMLLKQEGEHSASIISKQEIIMQEQSEQIL 1019
Query: 4201 SKDARLVEVEKKLKTYIEAGERVEALESEL--SYIRNSATA---LRESFLLKDSXXXXXX 4365
+ + K++ E ++ + +L YIRN + A LRE LK +
Sbjct: 1020 QLTDEVTHTQSKVQQTEEQYLEMKKMHDDLFEKYIRNKSEAEDLLREMENLKGTMESVEV 1079
Query: 4366 XXXXXXXXXXXFHARDILEKVEWLARSANGNSSRPSGWDQKSSDGGAGFVLSEPWREDVQ 4545
D ++E R + Q LS+
Sbjct: 1080 KIA------------DTKHELEETIRDKEQLLHEKKYFFQAMQTIFPITPLSDSLPPSKL 1127
Query: 4546 TGTSSEDDLRIKFEELKGKFYGLAEQNEMLEQSLMERNTLVQRWEKLLENIDIPPQLHSM 4725
+S+D + I + E+N ++ ERN+L + + ID+ QL S+
Sbjct: 1128 VEGNSQDPIEIN--DYHNLIALATERNNIMVCLETERNSLKE------QVIDLNTQLQSL 1179
Query: 4726 EVENKIEWLASTITEATHDRDNLQQKIDNLEVYCQSVTTDLEVSQKQVGDVEGNLQSCVS 4905
+ ++ ++ +LQ+ +LE + ++E+ + + D + +++
Sbjct: 1180 QAQSI-------------EKSDLQKPKQDLEEGEVKLLLEMELLKGHLTDSQLSIEKLQL 1226
Query: 4906 ERVNLSERLESLIGDHESLSARGIHLEVENEKLQNQ----VKDLHEKLVEKLGNEEHFQT 5073
E + ++E+L++L + ++++ L+ E L+ + +DL E + + + ++ +
Sbjct: 1227 ENLEVTEKLQTLQEEMKNITIERNELQTNFEDLKAEHDSLKQDLSENIEQSIETQDELRA 1286
Query: 5074 IEGDLLSLRYMIDDVIQEDGLQDLALASNSENLDGVLRK---LIDYYKNLVKSSLPGETD 5244
+ +L + ++D Q+ L D ++ +S N D V + + +L L GE D
Sbjct: 1287 AQEELREQKQLVDSFRQQ--LLDCSVGISSPNHDAVANQEKVSLGEVNSLQSEMLRGERD 1344
Query: 5245 DNVCETRPSDADVRSGESLGAHGATSHGQHFELSDSNVVEATSRDIAVVETPDVASLTKD 5424
+ + A V E L AH + G++ E++ + ++I + ++ + L
Sbjct: 1345 ELQTSCK---ALVSELELLRAHVKSVEGENLEITKK--LNGLEKEI-LGKSEESEVLKSM 1398
Query: 5425 LDQALHVQKLTREERDLYMAKQ------------QSLVAENEALDKKIIXXXXXXXXXXX 5568
L+ +E+ + Y +K+ Q LV E E L ++
Sbjct: 1399 LENLKEDNNKLKEQAEEYSSKENQFSLEEVFSGSQKLVDEIEVLKAQLKAAEERLEIKDR 1458
Query: 5569 XSASVREKLNVAVRKGKALVQ-QRDSLKQTIEEVNAELG-RLKSEIIKRDEKLLEN--EK 5736
+ + N + +GK Q D + +I+ + E+ ++ E ++R++ LLE E+
Sbjct: 1459 DYFELVQTANTNLVEGKLETPLQADHEEDSIDRRSEEMEIKVLGEKLERNQYLLERLQEE 1518
Query: 5737 KFRELESYSVRVESLESECQLLKIHSQETEYLLQER-------------SGDINDPVMKL 5877
K + + +E+ L Q+ E LL E D + K
Sbjct: 1519 KLELSNKLEILQKEMETSVLLKDDLQQKLESLLSENIILKENIDTTLKHHSDTQAQLQKT 1578
Query: 5878 QRISQLFQTMSTTVTS---AEQESRKSRRXXXXXXXXXXXVQETNDSLQEDLSKFTYEIQ 6048
Q+ QL + ++ + QE S + E + K +E
Sbjct: 1579 QQELQLAKNLAIAASDNCPITQEKETSADCVHPLEEKILLLTEELHQKTNEQEKLLHEKN 1638
Query: 6049 QLSRXXXXXXXXXXXXI-SRFENLSAVSN--EEKNKLYAQLLSCGTS---VNSLRKILAG 6210
+L + + S E+ S++ + EK+ QLL+ V +K L
Sbjct: 1639 ELEQAQVELKCEVEHLMKSMIESKSSLESLQHEKHDTEQQLLALKQQMQVVTQEKKELQQ 1698
Query: 6211 TNSCLADIFIMDMEFLHHLKANMEL-------CAKKTGTDLSGLPQLS----TENLVDKE 6357
T+ L + HLK N+EL +KT + L + +++ + E
Sbjct: 1699 THEHLT-------AEVDHLKENIELGLNFKNEAQQKTTKEQCLLNENKELEQSQHRLQCE 1751
Query: 6358 IFARLSAAWSNINLHETSSGGNIAEICGSLSQNLDQFVVGVSHLEEKVSKHLATWHDQIN 6537
I + + + ET I +L+Q ++ ++ + L+ +A +
Sbjct: 1752 IEELMKSLKDKESALETLKESEQKVI--NLNQEMEMVMLEMEELKNSQRTVIAERDQLQD 1809
Query: 6538 IVSNSIDTFFKSIGTGTD-------------------SEVAALGERIALLHGACSSVLVE 6660
+ S++ SI T D S+++ L E+I+LL + +L
Sbjct: 1810 DLRESVEM---SIETQDDLRKAQEALQQQKDKVQELTSQISVLQEKISLLE---NQMLYN 1863
Query: 6661 IERRKAELVGNDDFNMSLHQVDEDFSSME-SVRSMVNRLSSAVKELVVANAETLERNEKE 6837
+ K L DD N S + + ++ S++ L A K+ A +T++ EK
Sbjct: 1864 VATVKETLSERDDLNQSKQHLFSEIETLSLSLKEKEFALEQAEKDKADAARKTIDITEK- 1922
Query: 6838 MKVIIANLQRELHEKDIQNNRTC--NELVGQVKEAQAGAKIFAEDLQSASARMRDMQDQL 7011
I+N++ +L ++ T E + Q KE A + E L+ + + +D+ L
Sbjct: 1923 ----ISNIEEQLLQQATNLKETLYERESLIQCKEQLA---LNTEHLRE-TLKSKDLA--L 1972
Query: 7012 GILVRERDSMKERVKELLAGQASHSE-LQEKVTSLSDLLAAKDL-------------EIE 7149
G + +ERD +V L +S E + E VT+L + K+ ++E
Sbjct: 1973 GKMEQERDEAANKVIALTEKMSSLEEQINENVTTLKEGEGEKETFYLQRPSKQQSSSQME 2032
Query: 7150 ALMQALDEEESQMEDLKLRVTELEQEVQQKNLDLQKAEASRGKISKKLSITVDKFDELHH 7329
L ++L ++ Q+E+ + ++E E++ + E + + L+ V + + L H
Sbjct: 2033 ELRESLKTKDLQLEEAEKEISEATNEIKNLTAKISSLEEEILQNASILNEAVSERENLRH 2092
Query: 7330 LSENLLAEIEKLQQQVQDRDTEVSFLRQEVTRCTNE--------ALAASQMGTKRDSEE- 7482
+ L++E+E+L ++ RD + ++E N+ + +M RDS+E
Sbjct: 2093 SKQQLVSELEQLSLTLKSRDHAFAQSKREKDEAVNKIASLAEEIKILTKEMDEFRDSKES 2152
Query: 7483 IQTVLSWFDTIASLLGIEDSLSTDADSHINHYMETFEKRIASMLSEIDELRLVGQSKDVL 7662
+Q S E + IN+ + K + +L + L+ +
Sbjct: 2153 LQEQSSHLSEELCTYKTELQMLKQQKEDINNKLAEKVKEVDELLQHLSSLKEQLDQIQME 2212
Query: 7663 LEGERSRVAELRQKEATLEK-----FLLEKESQQD 7752
L E+ R EL +K +EK L++ E QQ+
Sbjct: 2213 LRNEKLRNYELCEKMDIMEKEISVLRLMQNEPQQE 2247
Score = 82.8 bits (203), Expect = 8e-14
Identities = 277/1555 (17%), Positives = 599/1555 (37%), Gaps = 120/1555 (7%)
Frame = +1
Query: 3619 EAVRKILSERLELQSVIDKLQSDLSSKSNDMEEMTQRSLDSTSXXXXXXXXXXXXXXXSG 3798
E +K L + EL+ I +L+ LS K+ ++E +T S +
Sbjct: 566 EEEKKELVQSFELK--IAELEEQLSVKAKNLEMVTNSREHSINAEVQTDVEKEVVRKEMS 623
Query: 3799 VIFESPSSQVEFLVSQLVQKFIEIEELANLL------RKQLEAKGNELMEIEESLLHHKT 3960
V+ +S + S L ++ + L++ RK LE K +L E E+L + K+
Sbjct: 624 VLGDSGYNASN---SDLQDSSVDGKRLSSSHDECIEHRKMLEQKIVDLEEFIENL-NKKS 679
Query: 3961 KIAGLRESLTQAEESLVAVRSELQDKSNELEQSEQRLLSTREKLSIAVTKGKGLIVQRDN 4140
+ + S ES+ + + +K+N LE+ L++ +I++ +
Sbjct: 680 ENDKQKSSEQDFMESIQLCEAIMAEKANALEE-----------LALMRDNFDNIILENET 728
Query: 4141 VKQSLAEASAKLQKCSE----ELNSKD------ARLVEVEKKLKTYIEAGERV-----EA 4275
+K+ +A+ L++ E E+ K+ A+L+ LK +E E E
Sbjct: 729 LKREIADLERSLKENQETNEFEILEKETQKEHEAQLIHEIGSLKKLVENAEMYNQNLEED 788
Query: 4276 LESELSYIRNSATALRESFLLKDSXXXXXXXXXXXXXXXXXFHARDILEKVEWLARSANG 4455
LE++ ++ L E L+ + + E++ L +S +
Sbjct: 789 LETKTKLLKEQEIQLAE---LRKRADNLQKKVRNFDLSVSMGDSEKLCEEIFQLKQSLSD 845
Query: 4456 NSSRPSGWDQKSSDGGAGFVLSEPWREDVQTGTSSEDDLRIKFE-ELKGKFYGLAEQNEM 4632
+ ++ S + + + ED + ++ FE +L+ + +
Sbjct: 846 AEAVTRDAQKECSFLRSENLELKEKMEDTSNWYNQKEKAASLFEKQLETEKSNYKKMEAD 905
Query: 4633 LEQSLMERNTLVQRWEKLLENIDIPPQLHSMEVENKIEWLASTITEATHDRDNLQQKIDN 4812
L++ L + LL L +E+E K+ + + +A +++ L+ ++
Sbjct: 906 LQKELQSAFNEINYLNGLLAGKVPRDLLSRVELEKKVSEFSKQLEKALEEKNALENEVTC 965
Query: 4813 LEVYCQSVTTDLEVSQKQVGDV---------EGNLQSCV--SERVNLSERLESLIGDHES 4959
L Y + + ++E + Q+ EG + + + + + E+ E ++
Sbjct: 966 LSEY-KFLPNEVECLKNQISKASEEIMLLKQEGEHSASIISKQEIIMQEQSEQIL----Q 1020
Query: 4960 LSARGIHLEVENEKLQNQ---VKDLHEKLVEK-LGNEEHFQTIEGDLLSLRYMIDDVIQE 5127
L+ H + + ++ + Q +K +H+ L EK + N+ + + ++ +L+ ++ V
Sbjct: 1021 LTDEVTHTQSKVQQTEEQYLEMKKMHDDLFEKYIRNKSEAEDLLREMENLKGTMESV--- 1077
Query: 5128 DGLQDLALASNSENLDGVLRKLIDYYKNLVKSSLPGETDDNVCETRPSDADVRSGESLGA 5307
++ +A L+ +R D + L + + + P + + +
Sbjct: 1078 ----EVKIADTKHELEETIR---DKEQLLHEKKYFFQAMQTIFPITPLSDSLPPSKLVEG 1130
Query: 5308 HGATSHGQHFELSDSN--VVEATSRDIAVV----ETPDVASLTKDLDQALH-VQKLTREE 5466
+ E++D + + AT R+ +V E + DL+ L +Q + E+
Sbjct: 1131 NSQDP----IEINDYHNLIALATERNNIMVCLETERNSLKEQVIDLNTQLQSLQAQSIEK 1186
Query: 5467 RDLYMAKQQ------SLVAENEALDKKIIXXXXXXXXXXXXSASVREKLNVAVRKGKALV 5628
DL KQ L+ E E L + + V EKL + K +
Sbjct: 1187 SDLQKPKQDLEEGEVKLLLEMELLKGHLTDSQLSIEKLQLENLEVTEKLQTLQEEMKNIT 1246
Query: 5629 QQRDSLKQTIEEVNAELGRLKSEIIKRDEKLLENEKKFRELESYSVRVESLESECQLLKI 5808
+R+ L+ E++ AE LK ++ + E+ +E + + R + E L + QL+
Sbjct: 1247 IERNELQTNFEDLKAEHDSLKQDLSENIEQSIETQDELRAAQ------EELREQKQLVDS 1300
Query: 5809 HSQETEYLLQERSGDINDPVMKLQRISQLFQTMSTTVTSAEQESRKSRRXXXXXXXXXXX 5988
Q+ S +D V +++S L + S E + +
Sbjct: 1301 FRQQLLDCSVGISSPNHDAVANQEKVS-LGEVNSLQSEMLRGERDELQTSCKALVSELEL 1359
Query: 5989 VQETNDSLQEDLSKFTYEIQQLSRXXXXXXXXXXXXISRFENLSAVSNEEKNKLYAQLLS 6168
++ S++ + + T ++ L + S ENL E+ NKL Q
Sbjct: 1360 LRAHVKSVEGENLEITKKLNGLEKEILGKSEESEVLKSMLENLK----EDNNKLKEQAEE 1415
Query: 6169 CGTSVN--SLRKILAGTNSCLADIFIMDMEFLHHLKANMELCAKKTGTDLSGLPQLSTEN 6342
+ N SL ++ +G+ + +I ++ + LKA E K D L Q + N
Sbjct: 1416 YSSKENQFSLEEVFSGSQKLVDEIEVLKAQ----LKAAEERLEIKD-RDYFELVQTANTN 1470
Query: 6343 LVDKEIFARLSAAWSNINLHETSSGGNIAEICGSLSQNLDQFVVGVSHLEEKVSKHLATW 6522
LV+ ++ L A ++ S I + L +N +L E++ +
Sbjct: 1471 LVEGKLETPLQADHEEDSIDRRSEEMEIKVLGEKLERN--------QYLLERLQEEKLEL 1522
Query: 6523 HDQINIVSNSIDTFFKSIGTGTD---------SEVAALGERI--ALLHGACSSVLVEIER 6669
+++ I+ ++T S+ D SE L E I L H + + ++ +
Sbjct: 1523 SNKLEILQKEMET---SVLLKDDLQQKLESLLSENIILKENIDTTLKHHSDTQAQLQKTQ 1579
Query: 6670 RKAELVGN----DDFNMSLHQVDEDFSSMESVRSMVNRLSSAVKEL---------VVANA 6810
++ +L N N + Q E +S + V + ++ +EL ++
Sbjct: 1580 QELQLAKNLAIAASDNCPITQEKE--TSADCVHPLEEKILLLTEELHQKTNEQEKLLHEK 1637
Query: 6811 ETLERNEKEMKVIIANLQRELHEKDIQNNRTCNELVGQVKEAQAGAKIFAEDLQSASARM 6990
LE+ + E+K + +L + + I++ + L + + + + +Q +
Sbjct: 1638 NELEQAQVELKCEVEHLMKSM----IESKSSLESLQHEKHDTEQQLLALKQQMQVVTQEK 1693
Query: 6991 RDMQDQLGILVRERDSMKERVKELLAGQASHSELQEKVTSLSDLLAA-KDLE-------- 7143
+++Q L E D +KE ++ G +E Q+K T LL K+LE
Sbjct: 1694 KELQQTHEHLTAEVDHLKENIE---LGLNFKNEAQQKTTKEQCLLNENKELEQSQHRLQC 1750
Query: 7144 -IEALMQALDEEESQMEDLK--------------LRVTELEQEVQQKNLDLQKAEASRGK 7278
IE LM++L ++ES +E LK + + E+E+ + + + + +
Sbjct: 1751 EIEELMKSLKDKESALETLKESEQKVINLNQEMEMVMLEMEELKNSQRTVIAERDQLQDD 1810
Query: 7279 ISKKLSITVDKFDELHHLSENLLAEIEKLQQQVQDRDTEVSFLRQEVTRCTNEAL----A 7446
+ + + ++++ D+L E L ++ + +VQ+ +++S L+++++ N+ L
Sbjct: 1811 LRESVEMSIETQDDLRKAQEAL----QQQKDKVQELTSQISVLQEKISLLENQMLYNVAT 1866
Query: 7447 ASQMGTKRD--SEEIQTVLSWFDTIASLL-----GIEDSLSTDADS---------HINHY 7578
+ ++RD ++ Q + S +T++ L +E + AD+ I++
Sbjct: 1867 VKETLSERDDLNQSKQHLFSEIETLSLSLKEKEFALEQAEKDKADAARKTIDITEKISNI 1926
Query: 7579 METFEKRIASMLSEIDELRLVGQSKDVLLEGERSRVAELRQKEATLEKFLLEKESQQDXX 7758
E ++ ++ + E + Q K+ L L+ K+ L K E++ +
Sbjct: 1927 EEQLLQQATNLKETLYERESLIQCKEQLALNTEHLRETLKSKDLALGKMEQERDEAANKV 1986
Query: 7759 XXXXXXXXXXXPLINKWTKTSIPSQVRSLRKGNMDQVAISIDADQTDQSGSLEED 7923
IN+ V +L++G ++ + QS S E+
Sbjct: 1987 IALTEKMSSLEEQINE--------NVTTLKEGEGEKETFYLQRPSKQQSSSQMEE 2033
Score = 65.1 bits (157), Expect = 2e-08
Identities = 253/1367 (18%), Positives = 518/1367 (37%), Gaps = 97/1367 (7%)
Frame = +1
Query: 3940 SLLHHKTKIAGLRESLTQAEESLVAVRSELQDKSNELE----QSEQRLLSTREKLSIAVT 4107
S + H+ K + L +S+ + +V+ K N+L+ S + +T
Sbjct: 498 SKVTHREKTS-LHQSMIDFGQISDSVQFHDSSKENQLQYLPKDSGDMAECRKASFEKEIT 556
Query: 4108 KGKGLIVQRDNVKQSLAEA-SAKLQKCSEELNSKDARLVEV----EKKLKTYIEAGERVE 4272
+ + ++ K+ L ++ K+ + E+L+ K L V E + ++ E
Sbjct: 557 SLQQQLQSKEEEKKELVQSFELKIAELEEQLSVKAKNLEMVTNSREHSINAEVQTDVEKE 616
Query: 4273 ALESELSYIRNSATALRESFLLKDSXXXXXXXXXXXXXXXXXFHARDILEKVEWLARSAN 4452
+ E+S + +S S L S H + + +K+ L
Sbjct: 617 VVRKEMSVLGDSGYNASNSDLQDSSVDGKRLSSSHDECIE---HRKMLEQKIVDLEEFIE 673
Query: 4453 GNSSRPSGWDQKSSDGGAGFVLSEPWREDVQTGTSSEDDLRIKFEEL---KGKFYGLAEQ 4623
+ + QKSS+ + + E +Q + + EEL + F + +
Sbjct: 674 NLNKKSENDKQKSSE--------QDFMESIQLCEAIMAEKANALEELALMRDNFDNIILE 725
Query: 4624 NEMLEQSLMERNTLVQRWEKLLENIDIPPQLHSMEVENKIEWLASTITEATHDRDNLQQK 4803
NE L++ + + E+ L+ + +E E + E A I H+ +L++
Sbjct: 726 NETLKREIADL-------ERSLKENQETNEFEILEKETQKEHEAQLI----HEIGSLKKL 774
Query: 4804 IDNLEVYCQSVTTDLEVSQKQVGDVEGNLQSCVSERVNLSERLESL-----IGDHESLSA 4968
++N E+Y Q++ DLE K + + E L NL +++ + +GD E L
Sbjct: 775 VENAEMYNQNLEEDLETKTKLLKEQEIQLAELRKRADNLQKKVRNFDLSVSMGDSEKLCE 834
Query: 4969 RGIHLEVENEKLQNQVKDLHEKLVEKLGNEEHFQTIEGDLLSLRYMIDDVIQEDGLQDLA 5148
L+ + +D ++ + + L L+ ++D ++ A
Sbjct: 835 EIFQLKQSLSDAEAVTRDA----------QKECSFLRSENLELKEKMEDTSNWYNQKEKA 884
Query: 5149 LA----------SNSENLDGVLRK-------LIDYYKNLVKSSLPGETDDNV-CETRPSD 5274
+ SN + ++ L+K I+Y L+ +P + V E + S+
Sbjct: 885 ASLFEKQLETEKSNYKKMEADLQKELQSAFNEINYLNGLLAGKVPRDLLSRVELEKKVSE 944
Query: 5275 ADVRSGESLGAHGATSHGQHFELSD----SNVVEATSRDIAVVETPDVASLTKDLDQALH 5442
+ ++L A + + LS+ N VE I+ + ++ L ++ + +
Sbjct: 945 FSKQLEKALEEKNALEN-EVTCLSEYKFLPNEVECLKNQISKA-SEEIMLLKQEGEHSAS 1002
Query: 5443 VQKLTREERDLYMAKQQSLVAENEA--LDKKIIXXXXXXXXXXXXSASVREKLNVAVRKG 5616
+ ++++E + +Q L +E K+ + EK +
Sbjct: 1003 I--ISKQEIIMQEQSEQILQLTDEVTHTQSKVQQTEEQYLEMKKMHDDLFEKYIRNKSEA 1060
Query: 5617 KALVQQRDSLKQTIEEVNAELGRLKSEIIK--RDEKLLENEKKF---------------- 5742
+ L+++ ++LK T+E V ++ K E+ + RD++ L +EKK+
Sbjct: 1061 EDLLREMENLKGTMESVEVKIADTKHELEETIRDKEQLLHEKKYFFQAMQTIFPITPLSD 1120
Query: 5743 ---------------RELESYSVRVESLESECQLLKIHSQETEYLLQERSGDINDPVMKL 5877
E+ Y + +L +E + + + L+E+ D+N + L
Sbjct: 1121 SLPPSKLVEGNSQDPIEINDYH-NLIALATERNNIMVCLETERNSLKEQVIDLNTQLQSL 1179
Query: 5878 QRISQLFQTMSTTVTSAEQESRKSRRXXXXXXXXXXXVQETNDSLQEDLSKFTYEIQQLS 6057
Q S + E+ K Q + + LQ + + T ++Q L
Sbjct: 1180 QAQSIEKSDLQKPKQDLEEGEVKLLLEMELLKGHLTDSQLSIEKLQLENLEVTEKLQTLQ 1239
Query: 6058 RXXXXXXXXXXXXISRFENLSAVSNEEKNKLYAQLLSCGTSVNSLRKIL--AGTNSCLAD 6231
+ FE+L A + K L + + + LR L D
Sbjct: 1240 EEMKNITIERNELQTNFEDLKAEHDSLKQDLSENIEQSIETQDELRAAQEELREQKQLVD 1299
Query: 6232 IF---IMDMEFLHHLKANMELCAKKTGTDLSGLPQLSTENLVDK--EIFARLSAAWSNIN 6396
F ++D + N + A + L + L +E L + E+ A S +
Sbjct: 1300 SFRQQLLDCS-VGISSPNHDAVANQEKVSLGEVNSLQSEMLRGERDELQTSCKALVSELE 1358
Query: 6397 L---HETSSGGNIAEICGSLSQNLDQFVVGVSHLEEKVSKHLATWHDQINIVSNSIDTFF 6567
L H S G EI L+ L++ ++G S E + L + N + + +
Sbjct: 1359 LLRAHVKSVEGENLEITKKLN-GLEKEILGKSEESEVLKSMLENLKEDNNKLKEQAEEYS 1417
Query: 6568 KSIGTGTDSEVAALGERIALLHGACSSVLVEIERRKAELVGNDDFNMSLHQVDEDFSSME 6747
+ EV + +++ + EIE KA+L ++ L D D+ +
Sbjct: 1418 SKENQFSLEEVFSGSQKL----------VDEIEVLKAQLKAAEE---RLEIKDRDYFELV 1464
Query: 6748 SVRSMVNRLSSAVKELVVANAE--TLERNEKEMKVIIANLQRELHEKDIQNNRTCNELVG 6921
+ N + ++ + A+ E +++R +EM++ + L EK +N L
Sbjct: 1465 QTAN-TNLVEGKLETPLQADHEEDSIDRRSEEMEI------KVLGEKLERNQYLLERLQE 1517
Query: 6922 QVKEAQAGAKIFAEDLQSASARMRDMQDQLGILVRERDSMKERVKELLAGQASHSELQEK 7101
+ E +I ++++++ D+Q +L L+ E +KE + L HS+ Q +
Sbjct: 1518 EKLELSNKLEILQKEMETSVLLKDDLQQKLESLLSENIILKENIDTTL---KHHSDTQAQ 1574
Query: 7102 V-TSLSDLLAAKDLEIEA-----LMQALDEEESQMEDLKLRVTELEQEVQQKNLDLQKAE 7263
+ + +L AK+L I A + Q + + L+ ++ L +E+ QK + +K
Sbjct: 1575 LQKTQQELQLAKNLAIAASDNCPITQEKETSADCVHPLEEKILLLTEELHQKTNEQEKLL 1634
Query: 7264 ASRGKISKKLSITVDKFDELHHLSENLL---AEIEKLQQQVQDRDTEVSFLRQEVTRCTN 7434
+ ++ + V+ E+ HL ++++ + +E LQ + D + ++ L+Q++ T
Sbjct: 1635 HEKNELEQ---AQVELKCEVEHLMKSMIESKSSLESLQHEKHDTEQQLLALKQQMQVVTQ 1691
Query: 7435 EALAASQMGTKRDSEEIQTVLSWFDTIASLLGIEDSLSTDADSHINHYMETFEK--RIAS 7608
E +E+Q T L D L + + +N E +K +
Sbjct: 1692 E------------KKELQ------QTHEHLTAEVDHLKENIELGLNFKNEAQQKTTKEQC 1733
Query: 7609 MLSEIDELRLVGQSKDVLLEGERSRVAELRQKEATLEKFLLEKESQQ 7749
+L+E EL QS+ L + L+ KE+ LE KES+Q
Sbjct: 1734 LLNENKELE---QSQHRLQCEIEELMKSLKDKESALETL---KESEQ 1774
Score = 53.9 bits (128), Expect = 4e-05
Identities = 103/539 (19%), Positives = 207/539 (38%), Gaps = 15/539 (2%)
Frame = +1
Query: 700 DQVTDVGEMQEEDMEQFSELSAKAGV--DKIATEERQTSY--PAVVDSSASPSHFSEGSS 867
D + E ++ ++ EL+++ V +KI+ E Q Y V ++ + ++
Sbjct: 1823 DDLRKAQEALQQQKDKVQELTSQISVLQEKISLLENQMLYNVATVKETLSERDDLNQSKQ 1882
Query: 868 VAFDTVELEGINGNFRSQQIREAAELNEEKPETSIDFPNNRDHV-----LSAEPEESSVA 1032
F +E ++ + + +A + + +ID ++ A + ++
Sbjct: 1883 HLFSEIETLSLSLKEKEFALEQAEKDKADAARKTIDITEKISNIEEQLLQQATNLKETLY 1942
Query: 1033 EMASQLQLPESVSISGVLSHEETRKIDTLNLSAELTSAHVHEGRSVSFLQLMDIVKGLGQ 1212
E S +Q E ++ L+ E R +TL S +L + + R + +++ + + +
Sbjct: 1943 ERESLIQCKEQLA----LNTEHLR--ETLK-SKDLALGKMEQERDEAANKVIALTEKMSS 1995
Query: 1213 DEYQILCNAREAASST-EPGTSSLERLREELFVSSTMEDILHVQLTEQSHLQIEFDHQHN 1389
E QI N E T L+R ++ SS ME++ T+ L+ E + + +
Sbjct: 1996 LEEQINENVTTLKEGEGEKETFYLQRPSKQQS-SSQMEELRESLKTKDLQLE-EAEKEIS 2053
Query: 1390 QFVAEISQLRASYSAVTERNDSLAEELSECQSKLYAATSSNTNLENQLLATEAQVEDFTA 1569
+ EI L A S SL EE+ + S L A S NL + +++E +
Sbjct: 2054 EATNEIKNLTAKIS-------SLEEEILQNASILNEAVSERENLRHSKQQLVSELEQLSL 2106
Query: 1570 KMNXXXXXXXXXXXXXXXXXXXFINLQVENDTLVAVISSMNDXXXXXXXXXXXXNYEIKH 1749
+ +L E L + D + H
Sbjct: 2107 TLKSRDHAFAQSKREKDEAVNKIASLAEEIKILTKEMDEFRDSKESLQE-------QSSH 2159
Query: 1750 LSSELCNCKNLAAILKAEVEQFENTIGPLTDEKIHLVEEKYSLLGEAEKLQEELANCKTV 1929
LS ELC K +LK + E N + E L++ SL + +++Q EL N
Sbjct: 2160 LSEELCTYKTELQMLKQQKEDINNKLAEKVKEVDELLQHLSSLKEQLDQIQMELRN---- 2215
Query: 1930 VTLQEVENSNMKETLSLLTRQQTMFE--ENNIHLREENEKAHLELSAHLISETYLLSEYS 2103
+++ N + E + ++ ++ ++ +N E++ +++ E L E
Sbjct: 2216 ---EKLRNYELCEKMDIMEKEISVLRLMQNEPQQEEDDVAERMDILESRNQEIQELMEKI 2272
Query: 2104 N--LKEGYTLLNNKLLKFQGEKEHLVEENDKLTQEL-LTLQEHMSTVEEERTHLEVELR 2271
+ E +TLL++ + Q E E + + L TL +++ E L +L+
Sbjct: 2273 SAVYSEQHTLLSSLSSELQKETEAHKHCMLNIKESLSSTLSRSFGSLQTEHVKLNTQLQ 2331
Score = 45.8 bits (107), Expect = 0.011
Identities = 130/637 (20%), Positives = 243/637 (37%), Gaps = 18/637 (2%)
Frame = +1
Query: 5689 KSEIIKRDEKLLENEKKFREL-ESYSVRVESLESECQLLKIHSQETEYLLQERSGDINDP 5865
+ EI ++L E++ +EL +S+ +++ LE + L + ++ E + R IN
Sbjct: 552 EKEITSLQQQLQSKEEEKKELVQSFELKIAELEEQ---LSVKAKNLEMVTNSREHSINAE 608
Query: 5866 VMKLQRISQLFQTMSTTVTSAEQESRKSRRXXXXXXXXXXXVQETNDSLQEDLSKFTYEI 6045
V + + MS S S + + ++D E +I
Sbjct: 609 VQTDVEKEVVRKEMSVLGDSGYNASNSDLQDSSVDGKR---LSSSHDECIEHRKMLEQKI 665
Query: 6046 QQLSRXXXXXXXXXXXXISRFENLSAVSNEEKNKLYAQLLSCGTSVNSLRKILAGTNSCL 6225
L ENL+ S +K K Q S+ I+A + L
Sbjct: 666 VDLEEF--------------IENLNKKSENDKQKSSEQDFM--ESIQLCEAIMAEKANAL 709
Query: 6226 ADIFIMDMEFLHHLKANMELCAKKTGTDLSGLPQLSTEN----LVDKEIFARLSAAWSNI 6393
++ +M F + + N L K+ DL + + E +++KE A
Sbjct: 710 EELALMRDNFDNIILENETL--KREIADLERSLKENQETNEFEILEKETQKEHEAQL--- 764
Query: 6394 NLHETSSGGNIAEICGSLSQNLDQFVVGVSHLEEKVSKHLATWHDQINIVSNSIDTFFKS 6573
+HE S + E +QNL++ + + L ++ LA + + + + F S
Sbjct: 765 -IHEIGSLKKLVENAEMYNQNLEEDLETKTKLLKEQEIQLAELRKRADNLQKKVRNFDLS 823
Query: 6574 IGTGTDSEVAALGERIALLHGACSSVLVEIERRKAELVGNDDFNMSLHQVDEDFSSMESV 6753
+ G DSE L E I L + S + E N+ L + ED S+ +
Sbjct: 824 VSMG-DSE--KLCEEIFQLKQSLSDAEAVTRDAQKECSFLRSENLELKEKMEDTSNWYNQ 880
Query: 6754 RSMVNRLSSAVKELVVANAETLERNEKEMKVIIANLQRELHEKDIQNNRTCNELVGQVK- 6930
+ L K+L ET + N K+M+ A+LQ+EL + N L G+V
Sbjct: 881 KEKAASLFE--KQL-----ETEKSNYKKME---ADLQKELQSAFNEINYLNGLLAGKVPR 930
Query: 6931 ------EAQAGAKIFAEDLQSASARMRDMQDQLGILVRER--DSMKERVKELLAGQASHS 7086
E + F++ L+ A +++++ L + + E +K ++ +
Sbjct: 931 DLLSRVELEKKVSEFSKQLEKALEEKNALENEVTCLSEYKFLPNEVECLKNQISKASEEI 990
Query: 7087 ELQEKVTSLSDLLAAKDLEIEALMQALDEEESQMEDLKLRVTELEQEVQQKNLDLQKAEA 7266
L ++ S + +K E +MQ E+ Q+ D VT + +VQQ E
Sbjct: 991 MLLKQEGEHSASIISKQ---EIIMQEQSEQILQLTD---EVTHTQSKVQQ-------TEE 1037
Query: 7267 SRGKISKKLSITVDKFDELHHLSENLLAEIEKLQQQVQDRDTEVSFLRQEVTRCTNEALA 7446
++ K +K+ +E+LL E+E L+ ++ + +++ + E+
Sbjct: 1038 QYLEMKKMHDDLFEKYIRNKSEAEDLLREMENLKGTMESVEVKIADTKHELEE------- 1090
Query: 7447 ASQMGTKRDSEEIQTVLSWF----DTIASLLGIEDSL 7545
T RD E++ +F TI + + DSL
Sbjct: 1091 -----TIRDKEQLLHEKKYFFQAMQTIFPITPLSDSL 1122
>ref|NP_001804.1| centromere protein E; Centromere autoantigen E (312kD); centromere
protein E (312kD) [Homo
sapiens]|gi|399227|sp|Q02224|CENE_HUMAN CENTROMERIC
PROTEIN E (CENP-E PROTEIN)|gi|29865|emb|CAA78727.1|
CENP-E [Homo sapiens]|gi|284038|pir||S28261 centromere
protein E - human
Length = 2663
Score = 118 bits (296), Expect = 1e-24
Identities = 307/1660 (18%), Positives = 618/1660 (36%), Gaps = 152/1660 (9%)
Frame = +1
Query: 1270 TSSLERLREELFVSSTMEDILHVQLTEQSHLQIEFDHQHNQFVAEISQ--LRASYSAVTE 1443
+S +E LRE+ +++ + Q E + + + + + ++ Q A A+
Sbjct: 578 SSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDA 637
Query: 1444 RNDS--LAEELSECQSKLYAATSSNTNLENQLLATEAQVEDFTAKMNXXXXXXXXXXXXX 1617
+ +S L E E + K+ ++ +EN + ++Q+E KM
Sbjct: 638 KRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEA-KKKMQVDLEKELQSAFNE 696
Query: 1618 XXXXXXFINLQVENDTLVAV-----ISSMNDXXXXXXXXXXXXNYEIKHLSSELCNCKNL 1782
I+ +V D L + I+ + E+ L SEL + +
Sbjct: 697 ITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVI-LLSELKSLPSE 755
Query: 1783 AAILKAEVEQFENTIGPLTDEKIHLVEEKYSLLGEAEKLQEELANCKTVVTLQEVENSNM 1962
L+ E++ + +T EK L E + L EE+ K + + SN
Sbjct: 756 VERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQ---SNY 812
Query: 1963 KETLSLLTRQQTM---FEENNIHLREENEKAHLELSAHLISETYLL-SEYSNLKEGYTLL 2130
K T +T+ FE+ + EENE+ + E+ +L E S LK +
Sbjct: 813 KSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEI-VNLSKEAQKFDSSLGALKTELSYK 871
Query: 2131 NNKLLKFQGEKEHLVEENDKLTQELLTLQEHMSTVEEERTHLEVELREAIARLDKLAEEN 2310
+L + E + + E ++L ++L + TVE E+T + +L++ + + L +E
Sbjct: 872 TQELQEKTREVQERLNEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEK 931
Query: 2311 ---TSLTSSIMVEKARMVDNGSADVSGLINQEISEKLGRSSEIGVSKQSASFLENTQYTN 2481
L S+ +E+ D +D+ +N I + + + KQ + +
Sbjct: 932 DDLKQLQESLQIER----DQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKI 987
Query: 2482 LEEV------REYTSEFSALMKNLEKGEKMVQNLEEAIKQILTDSSVSKSSDKGATPAVS 2643
EEV E T E + G Q+LE Q LT + S
Sbjct: 988 SEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFS 1047
Query: 2644 KLIQAFXXXXXXXXXXXXNAQLTDDLSEADQFVSVNV--------QIRNXXXXXXXXXXN 2799
+ + QL DL E + N +++ +
Sbjct: 1048 LIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNH 1107
Query: 2800 ARKAGIQFNQLNDDRTSTNQRLEELNVEFASHQDHINVLEADTIESKVSFEALKHYSYEL 2979
A K + ++ D ++L+E + + Q + ++ + E + +++ EL
Sbjct: 1108 AIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNEL 1167
Query: 2980 QHKNHDLELLCDSLKLRNDNISVENTELNKKLNYCSLRIDXXXXXXXXXXXXXTSFLSTM 3159
++K LE ++ E EL +KLN + SF +
Sbjct: 1168 KNKELTLE-----------HMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETER 1216
Query: 3160 EEQLVALQDESERAMMVEHELTSLMSEFGEAVVRLDDCLLRSGTSGAHTGLDMTKRISGS 3339
+ +++ + + EL E +D+ LR S + T +I +
Sbjct: 1217 DHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDE--LRRSVS------EKTAQIINT 1268
Query: 3340 VDVAVNVIEDLKEKLEAAYVKHESTSN--KYEELKQSFNTL-------FEKNEFTASSMQ 3492
D+ + + L+E++ + + E N K E +++ N L K+ T + ++
Sbjct: 1269 QDLEKSHTK-LQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTLARIE 1327
Query: 3493 KVYADLTKLITESCGSAEMTSLEVENVAVFDPFRDGSFENLLEAVRKILSERLELQSVID 3672
L + ES + + E +N+ + + L E +R+ L++ E QS
Sbjct: 1328 MERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQS--- 1384
Query: 3673 KLQSDLSSKSNDME------EMTQ-------------------RSLDSTSXXXXXXXXXX 3777
K + L+ K D E EM Q + L +
Sbjct: 1385 KQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEK 1444
Query: 3778 XXXXXSGVIFESPSSQVEFLVSQLVQKFIEI--------------EELANLLRKQLEAKG 3915
+ +S S Q++ + ++V K +E EE N LR L K
Sbjct: 1445 DDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKE 1504
Query: 3916 NELMEIEESLLHHKTKIAGLRESLTQAEESL-VAVRSELQDKSNELEQSEQ--------- 4065
E+ I++ L K+ + + + EE L + SE+Q+ NEL+Q ++
Sbjct: 1505 TEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISEVQENVNELKQFKEHRKAKDSAL 1564
Query: 4066 ------------RLLSTREKLSIAVTK-------GKGLIVQRDNVKQSLAEASAKLQKCS 4188
RL ++E++ I + + + L ++RD +K++ E AK+++ S
Sbjct: 1565 QSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKE-S 1623
Query: 4189 EELNSKDARLVEVEKKLKTYIEAGERVEALESELSYIRNSATA-LRESFLLKDSXXXXXX 4365
+E + ++ V + + E E E++ + N T +R + +L ++
Sbjct: 1624 QEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRS 1683
Query: 4366 XXXXXXXXXXXFHARDILEKVEWLARSANGNSSRPSGWDQKSSDGGAGFVLSEPWREDVQ 4545
RD L VE + DQ L E RE +
Sbjct: 1684 VT----------KERDDLRSVEETLKVER---------DQ----------LKENLRETIT 1714
Query: 4546 TGTSSEDDLRIKFEELK------GKFYGLAEQ--NEM--LEQSLMERNTLVQRWE-KLLE 4692
+++L+I LK K G+ + NE+ +++ L N ++ + K+ E
Sbjct: 1715 RDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQE 1774
Query: 4693 NIDIPPQLHSMEVENKIEWLASTITEATHDRDNLQQKIDNLEVYCQSVTTDLEVSQKQVG 4872
+ I +H E + I+ L ++E T N+Q+ ++N Q +L+ ++ Q+
Sbjct: 1775 ELRI-AHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLI 1833
Query: 4873 DVEGNLQSCVSERVNLSERLESLIGDHESLSARGIHLEVENEKLQNQVKDLHEKLVEKLG 5052
++ ++ ++V+ E+L+ I D ++ LE+EN L ++ + E++ +
Sbjct: 1834 TLKKDVNE-TQKKVSEMEQLKKQIKDQSLTLSK---LEIENLNLAQELHENLEEMKSVMK 1889
Query: 5053 NEEHFQTIEGDLLSLRYMIDDVIQEDGLQDLAL-----------ASNSENLDGVLRKLID 5199
++ + +E L R + + +QE +DL + + E +D + K+ +
Sbjct: 1890 ERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISE 1949
Query: 5200 YYKNLVKSSLPGETDDNVCETRPSDADVRSGE-SLGAHGATSHGQHFELSDSNVVEATSR 5376
K + S + + D + E + +++ E L + H ++++ ++
Sbjct: 1950 --KTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFE 2007
Query: 5377 DIAVVETP-DVASLTKDLDQALHVQKLTREERDLYMAKQQSLVAENEALDKKIIXXXXXX 5553
+ + D LTK L ++L ++ +ERD ++SL E +
Sbjct: 2008 PNYLCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQF----------- 2056
Query: 5554 XXXXXXSASVREKLNVAVRKGKALVQQRDSLKQTIEEVNAELGRLKSEIIKRDEKL---- 5721
R++ N V+ K L+ D + +E + + R+K E++KR ++
Sbjct: 2057 -IATLREMIARDRQNHQVKPEKRLLS--DGQQHLMESLREKCSRIK-ELLKRYSEMDDHY 2112
Query: 5722 ---------LENE-------KKFRELESYSVRVESLESEC 5793
LE E KK + + SY +++ + EC
Sbjct: 2113 ECLNRLSLDLEKEIEFHRIMKKLKYVLSYVTKIKEEQHEC 2152
Score = 104 bits (259), Expect = 3e-20
Identities = 286/1445 (19%), Positives = 564/1445 (38%), Gaps = 185/1445 (12%)
Frame = +1
Query: 3922 LMEIE---ESLLHHKTKIAGLRESLTQAEESLVAVRSELQDKSNELEQS--EQRLLSTRE 4086
L EIE + L ++ I SL ++LV +L+ + E+E E+ L E
Sbjct: 479 LSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFE 538
Query: 4087 KLSIAVTKGKG--LIVQRDNVKQSLAEASAKLQKCSEELNSKDARLVEVE---KKLKTYI 4251
L K + LI + N+K + Q EL+SK L E E KKL+ YI
Sbjct: 539 ALERKTKKDQEMQLIHEISNLKNLVKHREVYNQDLENELSSKVELLREKEDQIKKLQEYI 598
Query: 4252 EAGERVEALESELSYIRNSATALRESFLLKDSXXXXXXXXXXXXXXXXXFHARDILEKVE 4431
++ +++E ++ +LSY S ++ + +K + + + LE E
Sbjct: 599 DS-QKLENIKMDLSY---SLESIEDPKQMKQTLFDAETVALDAKRESAFLRSEN-LELKE 653
Query: 4432 WLARSANGNSSRPSGWDQKSSDGGAGFVLSEPWREDVQTGTSSEDDLRIKFE-------- 4587
+ A + S A + +++Q+ + L +
Sbjct: 654 KMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLL 713
Query: 4588 ---ELKGKFYGL-------AEQNEMLEQS---LMERNTLVQRWEKLLENI-DIPPQLHSM 4725
EL+GK L E+NE L + L E +L E+L + I D +LH +
Sbjct: 714 CNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHII 773
Query: 4726 ------------EVENKIEWLASTITEATHDRDNLQQKIDNLEVYCQSVTT-DLEVSQKQ 4866
E++++ L I + D Q + + Q+ T ++ QK
Sbjct: 774 TSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKY 833
Query: 4867 VGDVEGNLQSCVSERVNLSERLESLIGDHESLSARGIHLEVENEKLQNQVKDLHEKLVEK 5046
+E N + E VNLS+ + SL A L + ++LQ + +++ E+L E
Sbjct: 834 KMVLEEN-ERMNQEIVNLSKEAQKF---DSSLGALKTELSYKTQELQEKTREVQERLNEM 889
Query: 5047 LGNEEHFQTIEGDLLSL---RYMIDDVIQEDGLQDLALASNSENLDGVLRKLIDYYKNLV 5217
+E + + L ++ + +I + +Q+ + L ++L + L +
Sbjct: 890 EQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESL-----QIE 944
Query: 5218 KSSLPGETDDNVCETRPSDADVRSG-ESLGAHGATSHGQHFELSDSNVVEATSRDIAVVE 5394
+ L + D V + +R+ ESL H T S + E SR+
Sbjct: 945 RDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQET-----INTLKSKISEEVSRN----- 994
Query: 5395 TPDVASLTKDLDQALHVQKLTREERDLYMAKQQSLVAENEALDKKIIXXXXXXXXXXXXS 5574
LH+++ T E +D + QQ +V +DKK +
Sbjct: 995 --------------LHMEENTGETKDEF---QQKMVG----IDKK---QDLEAKNTQTLT 1030
Query: 5575 ASVRE-KLNVAVRKGKALVQQRDSLKQTIEEVNAELGRLKSEIIKRDEKLLENEKKFREL 5751
A V++ ++ RK +L+Q+++ L+Q +E V AE +LK+++ + E +EN+++ R L
Sbjct: 1031 ADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLL 1090
Query: 5752 --------------ESYSVRVE-SLESECQLLKIHSQETEYLLQERSGDINDPVMKLQRI 5886
++++++ E L C L E E L+E+S + + +L +
Sbjct: 1091 GDELKKQQEIVAQEKNHAIKKEGELSRTCDRL----AEVEEKLKEKSQQLQEKQQQLLNV 1146
Query: 5887 SQLFQTMSTTVTSAE----QESRKSRRXXXXXXXXXXXVQETNDSLQE--DLSKFTYEIQ 6048
+ M + E + K Q+ N++ +E ++K ++
Sbjct: 1147 QEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLK 1206
Query: 6049 QLSRXXXXXXXXXXXXISRFENLSAVSNEEKNKLYAQLLSCGTSVNSLRKILAGTNSCLA 6228
+L + I E + EE + L +++ LR+ ++ + +
Sbjct: 1207 ELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQII 1266
Query: 6229 D----------------IFIMDMEFLHHLKANME----------LCAKKTGTDLSGLPQL 6330
+ + + E L ++K E L + T D + L ++
Sbjct: 1267 NTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTLARI 1326
Query: 6331 STENLVDKEIFARLSAAWSNINLHETSSGGNIAEICGSLSQNLDQFVVGVSHLEEKVSKH 6510
E L E F ++ T N+ I +L DQ + K+ +
Sbjct: 1327 EMERLRLNEKFQESQEEIKSL----TKERDNLKTIKEALEVKHDQLKEHIRETLAKIQES 1382
Query: 6511 LATWHDQINIVSNSIDTFFKSIGTGTDSEVAALGERIALLHGACSSVLVEIERRKAELVG 6690
+ +N+ +T +++ + E+ A + +E+ L
Sbjct: 1383 QSKQEQSLNMKEKDNET----------TKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQE 1432
Query: 6691 NDDFNMSLHQVDEDFSSMESV-RSMVNRLSSAVKELVVANAETLER-------------- 6825
+ D S+ + +D ++ V +S ++L +KE+V + ET E
Sbjct: 1433 SHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEET 1492
Query: 6826 --------NEKEMKVI------------IANLQRELHEKDIQNN----RTCNELVGQVKE 6933
+EKE ++ + N +E++EK+ Q N E V ++K+
Sbjct: 1493 INELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISEVQENVNELKQ 1552
Query: 6934 AQAGAKIFAEDLQSASA-------RMRDMQDQLGILVR--------------ERDSMKER 7050
+ K LQS + R+++ Q+++ I+++ ERD +KE
Sbjct: 1553 FKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKEN 1612
Query: 7051 VKELLAGQASHSELQE---KVTSLSDLLAAKDLEIEALMQALDEEESQMEDLK---LRVT 7212
KE++A E + K+T++++ K EIE L + + ++ +E+++ +R+T
Sbjct: 1613 TKEIVAKMKESQEKEYQFLKMTAVNE-TQEKMCEIEHLKEQFETQKLNLENIETENIRLT 1671
Query: 7213 ELEQE-------VQQKNLDLQKAE----ASRGKISKKLSITV----DKFDELH----HLS 7335
++ E V ++ DL+ E R ++ + L T+ +K +EL HL
Sbjct: 1672 QILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLK 1731
Query: 7336 ENLLAEIEKLQQQVQDRDTEVSFLRQEVTRCTNEALAASQMGTKRDSEEIQTVL-SWFDT 7512
E+ I+KL+ V ++ E+S +++++ +N+AL A + + + L +T
Sbjct: 1732 EH-QETIDKLRGIVSEKTNEISNMQKDLEH-SNDALKAQDLKIQEELRIAHMHLKEQQET 1789
Query: 7513 IASLLGIEDSLSTDADSHINHYMETFEKRIASMLSEI--DELRLVGQSKDVLLEGERSRV 7686
I L GI S TD S++ +E ++ + E+ +E +L+ KDV + +V
Sbjct: 1790 IDKLRGIV-SEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDV--NETQKKV 1846
Query: 7687 AELRQ 7701
+E+ Q
Sbjct: 1847 SEMEQ 1851
Score = 101 bits (252), Expect = 2e-19
Identities = 305/1596 (19%), Positives = 591/1596 (36%), Gaps = 124/1596 (7%)
Frame = +1
Query: 1645 LQVENDTLVAVISSMNDXXXXXXXXXXXXNYEIKHLSSELCNCKNLAAILKAEVEQFENT 1824
L+ E + + + ND + L E+ N KNL + + EN
Sbjct: 517 LRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHREVYNQDLENE 576
Query: 1825 IGPLTDEKIHLVEEKYSLLGEAEKLQEELANCKTVVTLQEVENSNMKETLSLLT------ 1986
+ K+ L+ EK + +KLQE + + Q++EN M + SL +
Sbjct: 577 LS----SKVELLREKED---QIKKLQEYIDS-------QKLENIKMDLSYSLESIEDPKQ 622
Query: 1987 RQQTMFEENNIHLREENEKAHLELSAHLISETYLLSEYSNLKEGYTLLNNKLLKFQGEKE 2166
+QT+F+ + L + E A +L SE LKE + +
Sbjct: 623 MKQTLFDAETVALDAKRESA------------FLRSENLELKE--------------KMK 656
Query: 2167 HLVEENDKLTQELLTLQEHMSTVEEERTHLEVELREAIARLDKLAEENTSLTSSIMVEKA 2346
L ++ ++ Q + ++ + LE EL+ A E T LTS I
Sbjct: 657 ELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAF-------NEITKLTSLI----- 704
Query: 2347 RMVDNGSADVSGLINQEISEKLGRSSEIGVSKQSASFLENTQYTNLEEVREYTSEFSALM 2526
+G L N E+ K+ + K+ +E + E + SE +L
Sbjct: 705 ----DGKVPKDLLCNLELEGKI-----TDLQKELNKEVEENEALREEVI--LLSELKSLP 753
Query: 2527 KNLEKGEKMVQNLEEAIKQILTDSSVSKSSDKGATPAVSKLIQAFXXXXXXXXXXXXNAQ 2706
+E+ K +Q+ E + I ++ S V L++ N +
Sbjct: 754 SEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYK 813
Query: 2707 LTDDLSEADQFVSVNVQIRNXXXXXXXXXXNARKAGIQFNQLNDDRTSTNQRLEELNVEF 2886
TD E F ++++ ++ + ++ NQ + L+ E
Sbjct: 814 STDQ--EFQNFKTLHMDFEQ-----------------KYKMVLEENERMNQEIVNLSKEA 854
Query: 2887 ASHQDHINVLEADTIESKVSFEALKHYSYELQHKNHDLELLCDSLKLRNDNISV---ENT 3057
+ L+ E + L+ + E+Q + +++E L + L+ R+ + E T
Sbjct: 855 QKFDSSLGALKT---ELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSPLQTVEREKT 911
Query: 3058 ELNKKLNYCSLRIDXXXXXXXXXXXXXTSFLSTMEEQLVALQDESERAMMVEHELTSLMS 3237
+ +KL + S ++ + D + + +L + +
Sbjct: 912 LITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALE 971
Query: 3238 ---EFGEAVVRLDDCLLRSGTSGAHT--GLDMTKRISGSVDVAVNVIEDLKEKLEAAYVK 3402
+ E + L + + H TK V ++ +DL+ K
Sbjct: 972 SLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTA 1031
Query: 3403 HESTSNKYEELKQSFNTLFEKNEFTASSMQKVYADLTKLITESCGSAEMTSLEVENVAVF 3582
+ E+ ++ F+ + EKNE ++ V A+ +L T+ + EMT E + +
Sbjct: 1032 DVKDNEIIEQQRKIFSLIQEKNELQ-QMLESVIAEKEQLKTDLKENIEMTIENQEELRLL 1090
Query: 3583 DPFRDGSFENLLEAVRKILSERLELQSVIDKL---QSDLSSKSNDMEEMTQRSLDSTSXX 3753
E + + + + EL D+L + L KS ++E Q+ L+
Sbjct: 1091 GDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLN----- 1145
Query: 3754 XXXXXXXXXXXXXSGVIFESPSSQVEFLVSQLVQKFIEIEELANLLRKQ---LEAKGNEL 3924
V+ +S++ +K EIE L N L+ + LE E
Sbjct: 1146 ------------------------VQEEMSEMQKKINEIENLKNELKNKELTLEHMETER 1181
Query: 3925 MEIEESLLHHKTKIAGL---RESLTQAEESLVAVRSELQDKSNELEQSEQRLLSTREKLS 4095
+E+ + L + ++ + R+ L + ++S R L+ E+E + L T+E+L
Sbjct: 1182 LELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATG---LQTKEELK 1238
Query: 4096 IAVTKGKGLIVQRDNVKQSLAEASAK------LQKCSEELNSKDARLVEVEKKL---KTY 4248
IA K D +++S++E +A+ L+K +L + L E ++ L K
Sbjct: 1239 IAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKV 1298
Query: 4249 IEAGERVEALE--SELSYIRNSATALR-ESFLLKDSXXXXXXXXXXXXXXXXXFHARDIL 4419
E E + LE +E S ++S T R E L+ + + + I
Sbjct: 1299 SETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIK 1358
Query: 4420 EKVE------------WLARSANGNSSRPSGWDQKSSDGGAGFVLSEPWREDVQTGTSSE 4563
E +E LA+ S + + K D ++SE E + S+
Sbjct: 1359 EALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSE--MEQFKPKDSAL 1416
Query: 4564 DDLRIKFEELKGKFYGLAEQNEMLEQSLMERNTLVQRWE-------KLLENIDIPPQLHS 4722
LRI+ E L G L E ++ ++ E++ L + E +L ENI H
Sbjct: 1417 --LRIEIEML-GLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHL 1473
Query: 4723 -------------MEVENKIEWLASTITEATHDRDNLQQKIDNLEVYCQSVTTDL----- 4848
E E I L ++E + +Q++++ + Q+ ++
Sbjct: 1474 ETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEE 1533
Query: 4849 EVSQKQVGDVEGN-----------------LQSCVSERVNLSERLES-------LIGDHE 4956
+++ KQ+ +V+ N LQS S+ + L+ RL+ +I + E
Sbjct: 1534 QLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKE 1593
Query: 4957 SLSARGIHLEVENEKLQNQVKDLHEKLVEKLGNEEHF--QTIEGDLLSLRYMIDDVIQED 5130
+ L++E ++L+ K++ K+ E E F T + I+ + ++
Sbjct: 1594 EMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQF 1653
Query: 5131 GLQDLALAS-NSEN--LDGVLRKLIDYYKNLVKS---------SLPGETD---DNVCETR 5265
Q L L + +EN L +L + ++ +++ K +L E D +N+ ET
Sbjct: 1654 ETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETI 1713
Query: 5266 PSDADVRSGESLGAHGATSHGQHFELSDSNVVEATSRDIAVVETPDVASLTKDLDQ---A 5436
D + + + H L + R I +T +++++ KDL+ A
Sbjct: 1714 TRDLEKQEELKI---------VHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA 1764
Query: 5437 LHVQKLTREERDLYMAKQQSLVAENEALDKKIIXXXXXXXXXXXXSASVREKLNVAVRKG 5616
L Q L +E +L +A L + E +DK V EK +
Sbjct: 1765 LKAQDLKIQE-ELRIAHMH-LKEQQETIDK--------------LRGIVSEKTDKLSNMQ 1808
Query: 5617 KALVQQRDSLKQTIEEVNAELGRLKSEIIKRDEKLLENEKKFRELESYSVRVESLESECQ 5796
K L L++ I+E+ A + ++I + + E +KK E+E +++
Sbjct: 1809 KDLENSNAKLQEKIQELKAN----EHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLS 1864
Query: 5797 LLKIHSQETEYLLQERSGDINDPVMK----LQRISQLFQTMSTTVTSAEQESR----KSR 5952
L+I + L E ++ VMK L+R+ + + + + QE++ + +
Sbjct: 1865 KLEIENLNLAQELHENLEEMKS-VMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQ 1923
Query: 5953 RXXXXXXXXXXXVQETNDSLQEDLSKFTYEIQQLSR 6060
+ +ET D L+E +S+ T +I + +
Sbjct: 1924 QELKTARMLSKEHKETVDKLREKISEKTIQISDIQK 1959
Score = 97.1 bits (240), Expect = 4e-18
Identities = 299/1611 (18%), Positives = 627/1611 (38%), Gaps = 152/1611 (9%)
Frame = +1
Query: 3352 VNVIEDLKEKLEAAYVKHESTSN----KYEELKQSFNTLFEKNEFTASS-MQKVYADLTK 3516
++ I +LK ++ V ++ N K E L++ + + + E+ S ++ + DL+
Sbjct: 553 IHEISNLKNLVKHREVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSY 612
Query: 3517 LIT--ESCGSAEMTSLEVENVAVFDPFRDGSFENLLEAVRKILSERLELQSVIDKLQSDL 3690
+ E + T + E VA+ D R+ +F + SE LEL+ + +L +
Sbjct: 613 SLESIEDPKQMKQTLFDAETVAL-DAKRESAF---------LRSENLELKEKMKELATTY 662
Query: 3691 SSKSNDMEEMTQRSLDSTSXXXXXXXXXXXXXXXSGVIFESPSSQVEFLVSQLVQKFIEI 3870
ND++ + Q L++ +S ++ V + + +E+
Sbjct: 663 KQMENDIQ-LYQSQLEAKKKMQVDLEKELQSAFNE---ITKLTSLIDGKVPKDLLCNLEL 718
Query: 3871 EELANLLRKQLEAKGNELMEIEESLLHHKTKIAGLRESLTQAEESLVAVRSELQDKSNEL 4050
E L+K+L N+ +E E+L ++ L+ ++ E +R E+QDKS EL
Sbjct: 719 EGKITDLQKEL----NKEVEENEALREEVILLSELKSLPSEVER----LRKEIQDKSEEL 770
Query: 4051 EQSEQRLLSTREKLSIAV----TKGKGLIVQRDNVKQSLAEASAKLQKCSEELNSKDARL 4218
+ S ++KL V ++ +GL+ + K LA + + +E +
Sbjct: 771 HI----ITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLH 826
Query: 4219 VEVEKKLKTYIEAGERVEA----LESELSYIRNSATALRESFLLKDSXXXXXXXXXXXXX 4386
++ E+K K +E ER+ L E +S AL+ K
Sbjct: 827 MDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKT------- 879
Query: 4387 XXXXFHARDILEKVEWLARSANGNSSRPSGWDQKSSDGGAGFVLSEPWREDVQTGTSSED 4566
R++ E++ + + +R S + + E+V+T T +D
Sbjct: 880 -------REVQERLNEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKD 932
Query: 4567 DLR-------IKFEELKGKFYGLAEQNEMLEQSLMERNTLVQRWEKLLENIDIPPQLHSM 4725
DL+ I+ ++LK + N ++ L RN L + ++ E I+ S
Sbjct: 933 DLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQL--RNAL-ESLKQHQETINTLKSKISE 989
Query: 4726 EVENKIEWLASTITEATHDRDNLQQKIDNLEVY-------CQSVTTDLEVSQKQVGDVEG 4884
EV + +T +D QQK+ ++ Q++T D V ++ + +
Sbjct: 990 EVSRNLHMEENT----GETKDEFQQKMVGIDKKQDLEAKNTQTLTAD--VKDNEIIEQQR 1043
Query: 4885 NLQSCVSERVNLSERLESLIGDHESLSA---RGIHLEVENEKLQNQVKDLHEKLVEKLGN 5055
+ S + E+ L + LES+I + E L I + +EN++ + D +K E +
Sbjct: 1044 KIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQ 1103
Query: 5056 EE-HFQTIEGDLLSLRYMIDDVIQEDGLQDLALASNSENLDGVLRKLIDYYKNLVKSSLP 5232
E+ H EG+L + +V ++ L S+ L ++L++ + +
Sbjct: 1104 EKNHAIKKEGELSRTCDRLAEVEEK-------LKEKSQQLQEKQQQLLNVQEEM------ 1150
Query: 5233 GETDDNVCETRPSDADVRSGESLGAHGATSHGQHFELSDSNVVEATSRDIAVVETPDVAS 5412
E + E ++++ E H T + + + N E V S
Sbjct: 1151 SEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEE-------------VKS 1197
Query: 5413 LTKDLDQALHVQKLTREERD------------------------LYMAKQQSLVAENEAL 5520
+TK+ +QK ERD +++ + Q + E
Sbjct: 1198 ITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRS 1257
Query: 5521 DKKIIXXXXXXXXXXXXSASVREKLNVAVRKGKAL--VQQRDSLKQTIEEV--------- 5667
+ ++E++ V + + L V++ ++T+ E+
Sbjct: 1258 VSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTT 1317
Query: 5668 --NAELGRLKSEIIKRDEKLLENEKKFREL----ESYSVRVESLESECQLLKIHSQETEY 5829
+ L R++ E ++ +EK E++++ + L ++ E+LE + LK H +ET
Sbjct: 1318 KDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLA 1377
Query: 5830 LLQERSGDINDPVMKLQRISQLFQTMSTTVTSAEQESRKSR-----RXXXXXXXXXXXVQ 5994
+QE + Q ++ + TT +E E K + R +Q
Sbjct: 1378 KIQESQSK------QEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQ 1431
Query: 5995 ETNDSLQEDLSKFTYEIQQLSRXXXXXXXXXXXXISRFENLSAVSNEEKNKLYAQLLSCG 6174
E++D ++ ++K ++Q+L I + EE + L
Sbjct: 1432 ESHDEMKS-VAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQE 1490
Query: 6175 TSVNSLRKILAGTNSCLADIFIMDMEFLHHLKAN--MELCAKKTGTDLSGLPQLSTENLV 6348
++N LR L+ + ++ I +E ++ N E+ K+ ++ + ++ EN+
Sbjct: 1491 ETINELRVNLSEKETEISTIQ-KQLEAINDKLQNKIQEIYEKEEQLNIKQISEVQ-ENVN 1548
Query: 6349 DKEIFARLSAAWSNINLHETSSGGNIAEICGSLSQNLDQFVVGVSHLEE--KVSKHLATW 6522
+ + F A + S + E+ L ++ ++ + + EE +V + L
Sbjct: 1549 ELKQFKEHRKAKDSAL---QSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIE 1605
Query: 6523 HDQIN-----IVSNSIDTFFKSIGTGTDSEVAALGERIALLHGACSSVLVEIERRKAELV 6687
DQ+ IV+ ++ K + V E++ + + + E +K L
Sbjct: 1606 RDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIE----HLKEQFETQKLNLE 1661
Query: 6688 GNDDFNMSLHQV-DEDFSSMESVRSMVNRLSSAVKELVVAN-------AETLERN-EKEM 6840
+ N+ L Q+ E+ M SV + L S + L V ET+ R+ EK+
Sbjct: 1662 NIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQE 1721
Query: 6841 KVIIANLQRELHEKDIQNNR-----TCNELVGQVKEAQ-------AGAKIFAEDLQSASA 6984
++ I ++ + H++ I R NE+ K+ + A E+L+ A
Sbjct: 1722 ELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHM 1781
Query: 6985 RMRDMQDQL----GILVRERDSMKERVKELLAGQASHSELQEKVTSLSD-----LLAAKD 7137
+++ Q+ + GI+ + D + K+L + S+++LQEK+ L + KD
Sbjct: 1782 HLKEQQETIDKLRGIVSEKTDKLSNMQKDL---ENSNAKLQEKIQELKANEHQLITLKKD 1838
Query: 7138 L--------EIEALMQALDEEESQMEDLKLRVTELEQEVQQKNLDLQKAEASRG---KIS 7284
+ E+E L + + ++ + L++ L QE+ + +++ R ++
Sbjct: 1839 VNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKERDNLRRVE 1898
Query: 7285 KKLSITVDKFDE------------------LHHLSENLLAEIEKLQQQVQDRDTEVSFLR 7410
+ L + D+ E LS+ ++KL++++ ++ ++S ++
Sbjct: 1899 ETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQ 1958
Query: 7411 QEVTRCTNEALAASQMGTKRDSEEIQTVLSWFDTIASLLGIEDSLSTDADSHINHY---- 7578
+++ + +E Q + +E+Q + D S I + N+
Sbjct: 1959 KDLDKSKDELQKKIQ---ELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEPNYLCKCE 2015
Query: 7579 METFEKRIASMLSE-IDELRLVGQSKDVLLEGERSRVAELRQKEATLEKFL 7728
M+ F+ + L E ++E+R+V + +D L + S E Q ATL + +
Sbjct: 2016 MDNFQ--LTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMI 2064
Score = 89.0 bits (219), Expect = 1e-15
Identities = 210/1143 (18%), Positives = 434/1143 (37%), Gaps = 155/1143 (13%)
Frame = +1
Query: 1330 LHVQLTEQSHLQIEFDHQHNQFVAEISQ--------LRASYSAVTERNDSLAEELSECQS 1485
LH+ ++ + +E + + NQ + +S+ L A + ++ + L E+ E Q
Sbjct: 825 LHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQE 884
Query: 1486 KLYAATSSNTNLENQ---LLATEAQVEDFTAKMNXXXXXXXXXXXXXXXXXXXFINLQVE 1656
+L LEN+ L E + T K+ +LQ+E
Sbjct: 885 RLNEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIE 944
Query: 1657 NDTLVA------------------VISSMNDXXXXXXXXXXXXNYEIK---HLSSELCNC 1773
D L + + S+ + E+ H+
Sbjct: 945 RDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGET 1004
Query: 1774 KN-----LAAILKAEVEQFENTIGPLTDEKIHLVEEK----YSLLGEAEKLQEELANCKT 1926
K+ + I K + + +NT D K + + E+ +SL+ E +LQ+ L ++
Sbjct: 1005 KDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQML---ES 1061
Query: 1927 VVTLQEVENSNMKETLSLLTRQQTMFEENNIHLREENEKAHLELSAHLISETYLLSEYSN 2106
V+ +E +++KE + + Q L+++ E E + + E L
Sbjct: 1062 VIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDR 1121
Query: 2107 LKEGYTLLNNKLLKFQGEKEHLVEENDKLTQ------ELLTLQEHMSTVEEERTHLEVEL 2268
L E L K + Q +++ L+ +++++ E+ L+ + E H+E E
Sbjct: 1122 LAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETER 1181
Query: 2269 REAIARLDKLAEENTSLTSS--IMVEKARMVDNGSADVSGLI------------------ 2388
E +L++ EE S+T ++ E + + + G I
Sbjct: 1182 LELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAH 1241
Query: 2389 -----NQEISEKLGRSSEIGVSKQSASFLENTQ-----YTNLEEVREYTSEFSALMKNLE 2538
+QE ++L RS VS+++A + NTQ +T L+E E L+ N++
Sbjct: 1242 IHLKEHQETIDELRRS----VSEKTAQII-NTQDLEKSHTKLQEEIPVLHEEQELLPNVK 1296
Query: 2539 KGEKMVQNLEEAIKQILTDSSVSKSSDKGATPAVSKLIQAFXXXXXXXXXXXXNAQLTDD 2718
K + + + E ++LT+ S +K S A + +L + + D+
Sbjct: 1297 KVSETQETMNEL--ELLTEQSTTKDSTTLARIEMERL-RLNEKFQESQEEIKSLTKERDN 1353
Query: 2719 LSEADQFVSV-NVQIRNXXXXXXXXXXNARKAGIQFNQLNDDRTSTNQRLEELNVEFASH 2895
L + + V + Q++ ++ Q + + T + + E+ +F
Sbjct: 1354 LKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEME-QFKPK 1412
Query: 2896 QDHINVLEADTI-------ESKVSFEALKHYSYELQHKNHDLELLCDSLKLRNDNISVEN 3054
+ +E + + ES +++ +LQ L+ D LK I ++
Sbjct: 1413 DSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKH 1472
Query: 3055 TELNKKLN--YCSLRI-DXXXXXXXXXXXXXTSFLSTMEEQLVALQDESERAMMVEHELT 3225
E ++L +C L+ + + +ST+++QL A+ D+ + + +E
Sbjct: 1473 LETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKE 1532
Query: 3226 SLM-----SEFGEAVVRLD---------DCLLRSGTSGAHTGLDMTKRISGS---VDVAV 3354
+ SE E V L D L+S S L++T R+ S + + +
Sbjct: 1533 EQLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESKM---LELTNRLQESQEEIQIMI 1589
Query: 3355 NVIEDLKEKLEAAYVKH---------------ESTSNKYEELKQS--------------F 3447
E++K EA ++ ES +Y+ LK +
Sbjct: 1590 KEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHL 1649
Query: 3448 NTLFEKNEFTASSMQKVYADLTKLITESCGSAEMTSLEVENVAVFDPF----RDGSFENL 3615
FE + +++ LT+++ E+ + E +++ + RD ENL
Sbjct: 1650 KEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENL 1709
Query: 3616 LEAVRKILSERLEL----------QSVIDKLQSDLSSKSNDMEEMTQRSLDSTSXXXXXX 3765
E + + L ++ EL Q IDKL+ +S K+N++ M + S
Sbjct: 1710 RETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQD 1769
Query: 3766 XXXXXXXXXSGVIFESPSSQVEFL---VSQLVQKFIEIEELANLLRKQLEAKGNELMEIE 3936
+ + + ++ L VS+ K +++ +L+ K EL E
Sbjct: 1770 LKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANE 1829
Query: 3937 ESLLHHKTKIAGLRESLTQAEESLVAVRSELQDKSNELEQSEQRLLSTREKLSIAVTKGK 4116
L+ K + ++ +++ E+ ++ +++D+S L + E L+ ++L + + K
Sbjct: 1830 HQLITLKKDVNETQKKVSEMEQ----LKKQIKDQSLTLSKLEIENLNLAQELHENLEEMK 1885
Query: 4117 GLIVQRDNVKQSLAEASAKLQKCSEELNSKDARLVEVEKKLKT----YIEAGERVEALES 4284
++ +RDN+++ + + E L AR +E++++LKT E E V+ L
Sbjct: 1886 SVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLRE 1945
Query: 4285 ELS 4293
++S
Sbjct: 1946 KIS 1948
Database: BlastDB/NCBI/blast/db/2003_02_27_02_00_4/nr
Posted date: Feb 27, 2003 4:02 PM
Number of letters in database: 431,508,457
Number of sequences in database: 1,347,713
Lambda K H
0.309 0.126 0.329
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
length of database: 431,508,457
effective HSP length: 141
effective length of database: 241,480,924
effective search space used: 620847455604
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)