BLASTX 1.4.13-Paracel [2002-12-12]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= At1g08260.f
(6816 letters)
Database: BlastDB/NCBI/blast/db/2003_02_27_02_00_4/nr
1,347,713 sequences; 431,508,457 total letters
Searching...................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|AAF18240.1|AC011438_2 T23G18.11 [Arabidopsis thaliana]|g... 4504 0.0
ref|NP_180280.1| putative DNA polymerase epsilon catalytic ... 3448 0.0
ref|XP_194234.1| polymerase (DNA directed), epsilon [Mus mu... 1586 0.0
gb|AAD46482.1| DNA polymerase epsilon catalytic subunit [Mu... 1583 0.0
gb|AAD45244.1|AF123502_1 DNA polymerase epsilon catalytic s... 1575 0.0
>gb|AAF18240.1|AC011438_2 T23G18.11 [Arabidopsis thaliana]|gi|15223158|ref|NP_172303.1| DNA
polymerase epsilon catalytic subunit, putative; protein
id: At1g08260.1 [Arabidopsis thaliana]
Length = 2271
Score = 4504 bits (11683), Expect = 0.0
Identities = 2222/2271 (97%), Positives = 2222/2271 (97%)
Frame = +1
Query: 1 MSGDNRRRDRKDTRWSKKPKVVNTAEDELESKLGFGLFSEGETRLGWLLTFSSSSWEDRD 180
MSGDNRRRDRKDTRWSKKPKVVNTAEDELESKLGFGLFSEGETRLGWLLTFSSSSWEDRD
Sbjct: 1 MSGDNRRRDRKDTRWSKKPKVVNTAEDELESKLGFGLFSEGETRLGWLLTFSSSSWEDRD 60
Query: 181 TGKVYSCVDLYFVTQDGFSFKTKYKFRPYFYAATKDKMXXXXXXXXXXXXXXQVADIEIV 360
TGKVYSCVDLYFVTQDGFSFKTKYKFRPYFYAATKDKM QVADIEIV
Sbjct: 61 TGKVYSCVDLYFVTQDGFSFKTKYKFRPYFYAATKDKMELELEAYLRRRYERQVADIEIV 120
Query: 361 EKEDLDLKNHLSGLQKKYLKISFDTVQQLMEVKRDLLHIVERNQAKFDALEAYESILAGK 540
EKEDLDLKNHLSGLQKKYLKISFDTVQQLMEVKRDLLHIVERNQAKFDALEAYESILAGK
Sbjct: 121 EKEDLDLKNHLSGLQKKYLKISFDTVQQLMEVKRDLLHIVERNQAKFDALEAYESILAGK 180
Query: 541 REQRPQDCLDSIVDLREYDVPYHVRFAIDNDVRSGQWYNVSISSTDVILEKRTDLLQRAE 720
REQRPQDCLDSIVDLREYDVPYHVRFAIDNDVRSGQWYNVSISSTDVILEKRTDLLQRAE
Sbjct: 181 REQRPQDCLDSIVDLREYDVPYHVRFAIDNDVRSGQWYNVSISSTDVILEKRTDLLQRAE 240
Query: 721 VRVCAFDIETTKLPLKFPDAEYDQIMMISYMVDGQGFLIINREVTACVGEDVEDLEYTPK 900
VRVCAFDIETTKLPLKFPDAEYDQIMMISYMVDGQGFLIINREVTACVGEDVEDLEYTPK
Sbjct: 241 VRVCAFDIETTKLPLKFPDAEYDQIMMISYMVDGQGFLIINREVTACVGEDVEDLEYTPK 300
Query: 901 PEFEGYFKVTNVKNEVELLQRWFYHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNE 1080
PEFEGYFKVTNVKNEVELLQRWFYHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNE
Sbjct: 301 PEFEGYFKVTNVKNEVELLQRWFYHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNE 360
Query: 1081 ELGFRCDQNQGECRAKFACHLDCFAWVKRDSYLPQGSHGLKAVTKAKLGYDPLEVNPEDM 1260
ELGFRCDQNQGECRAKFACHLDCFAWVKRDSYLPQGSHGLKAVTKAKLGYDPLEVNPEDM
Sbjct: 361 ELGFRCDQNQGECRAKFACHLDCFAWVKRDSYLPQGSHGLKAVTKAKLGYDPLEVNPEDM 420
Query: 1261 VRFAMEKPQTMASYSVSDAVATYYLYMTYVNPFIFSLATIIPMVPDEVLRKGSGTLCEML 1440
VRFAMEKPQTMASYSVSDAVATYYLYMTYVNPFIFSLATIIPMVPDEVLRKGSGTLCEML
Sbjct: 421 VRFAMEKPQTMASYSVSDAVATYYLYMTYVNPFIFSLATIIPMVPDEVLRKGSGTLCEML 480
Query: 1441 LMVEVSTYLPQAQAYKANVVCPNKNQADPEKFYQNQLLESETYIGGHVECLESGQLIDNL 1620
LMVEVSTYLPQAQAYKANVVCPNKNQADPEKFYQNQLLESETYIGGHVECLESGQLIDNL
Sbjct: 481 LMVEVSTYLPQAQAYKANVVCPNKNQADPEKFYQNQLLESETYIGGHVECLESGQLIDNL 540
Query: 1621 GRDLEYAITVEGKMRMDSISNYDEVKDEIKEKLEKLRDDPIREEGPLIYHLDVAAMYPNI 1800
GRDLEYAITVEGKMRMDSISNYDEVKDEIKEKLEKLRDDPIREEGPLIYHLDVAAMYPNI
Sbjct: 541 GRDLEYAITVEGKMRMDSISNYDEVKDEIKEKLEKLRDDPIREEGPLIYHLDVAAMYPNI 600
Query: 1801 ILTNRLQVHLISPPSIVTDEICTACDFNRPGKTCLRKLEWVWRGVTFMGKKSDYYHLKKQ 1980
ILTNRLQVHLISPPSIVTDEICTACDFNRPGKTCLRKLEWVWRGVTFMGKKSDYYHLKKQ
Sbjct: 601 ILTNRLQVHLISPPSIVTDEICTACDFNRPGKTCLRKLEWVWRGVTFMGKKSDYYHLKKQ 660
Query: 1981 IESEFVDAGANIMSSKSFLDLPKVDQQSKLKERLKKYCQKAYKRVLDKPITEVREAGICM 2160
IESEFVDAGANIMSSKSFLDLPKVDQQSKLKERLKKYCQKAYKRVLDKPITEVREAGICM
Sbjct: 661 IESEFVDAGANIMSSKSFLDLPKVDQQSKLKERLKKYCQKAYKRVLDKPITEVREAGICM 720
Query: 2161 RENPFYVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNSIKIQEAQDMVVVYDSLQLAH 2340
RENPFYVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNSIKIQEAQDMVVVYDSLQLAH
Sbjct: 721 RENPFYVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNSIKIQEAQDMVVVYDSLQLAH 780
Query: 2341 KCILNSFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDTDGIWCCL 2520
KCILNSFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDTDGIWCCL
Sbjct: 781 KCILNSFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDTDGIWCCL 840
Query: 2521 PGSFPENFTFKTIDMKKLTISYPCVMLNVDVAKNNTNDQYQTLVDPVRKTYKSHSECSIE 2700
PGSFPENFTFKTIDMKKLTISYPCVMLNVDVAKNNTNDQYQTLVDPVRKTYKSHSECSIE
Sbjct: 841 PGSFPENFTFKTIDMKKLTISYPCVMLNVDVAKNNTNDQYQTLVDPVRKTYKSHSECSIE 900
Query: 2701 FEVDGPYKAMIIPASKEEGILIKKRYAVFNHDGTLAELKGFEIKRRGELKLIKVFQAELF 2880
FEVDGPYKAMIIPASKEEGILIKKRYAVFNHDGTLAELKGFEIKRRGELKLIKVFQAELF
Sbjct: 901 FEVDGPYKAMIIPASKEEGILIKKRYAVFNHDGTLAELKGFEIKRRGELKLIKVFQAELF 960
Query: 2881 DKFLHGSTLEECYSAVAAVADRWLDLLDVCEISCFFWVIYLIGFLSHFLQNQGKDIADSE 3060
DKFLHGSTLEECYSAVAAVADRWLDLLDVCEISCFFWVIYLIGFLSHFLQNQGKDIADSE
Sbjct: 961 DKFLHGSTLEECYSAVAAVADRWLDLLDVCEISCFFWVIYLIGFLSHFLQNQGKDIADSE 1020
Query: 3061 LLDYISESSTMSKSLADYGEQKSCAVTTAKRLAEFLGVTMVKDKGLRCQYIVACEPKGTP 3240
LLDYISESSTMSKSLADYGEQKSCAVTTAKRLAEFLGVTMVKDKGLRCQYIVACEPKGTP
Sbjct: 1021 LLDYISESSTMSKSLADYGEQKSCAVTTAKRLAEFLGVTMVKDKGLRCQYIVACEPKGTP 1080
Query: 3241 VSERAVPVAIFTTNPEVMKFHLRKWCKTSSDVGIRLIIDWSYYKQRLSSAIQKVITIPAA 3420
VSERAVPVAIFTTNPEVMKFHLRKWCKTSSDVGIRLIIDWSYYKQRLSSAIQKVITIPAA
Sbjct: 1081 VSERAVPVAIFTTNPEVMKFHLRKWCKTSSDVGIRLIIDWSYYKQRLSSAIQKVITIPAA 1140
Query: 3421 MQKVANPVPRVLHPDWLHKKVREKDDKFRQRKLVDMFSSANKDVVLDTDLPVTKDNVEDI 3600
MQKVANPVPRVLHPDWLHKKVREKDDKFRQRKLVDMFSSANKDVVLDTDLPVTKDNVEDI
Sbjct: 1141 MQKVANPVPRVLHPDWLHKKVREKDDKFRQRKLVDMFSSANKDVVLDTDLPVTKDNVEDI 1200
Query: 3601 EDFCKENRPSVKGPKPIARSYEVNKKQSECEQQESWDTEFHDISFQNIDKSVNYQGWLEL 3780
EDFCKENRPSVKGPKPIARSYEVNKKQSECEQQESWDTEFHDISFQNIDKSVNYQGWLEL
Sbjct: 1201 EDFCKENRPSVKGPKPIARSYEVNKKQSECEQQESWDTEFHDISFQNIDKSVNYQGWLEL 1260
Query: 3781 KKRKWKVTLEKKKKRRLGDLRSSNQVDTHEINQKVGQGRGGVGSYFRRPEEALTSSHWQV 3960
KKRKWKVTLEKKKKRRLGDLRSSNQVDTHEINQKVGQGRGGVGSYFRRPEEALTSSHWQV
Sbjct: 1261 KKRKWKVTLEKKKKRRLGDLRSSNQVDTHEINQKVGQGRGGVGSYFRRPEEALTSSHWQV 1320
Query: 3961 CTIIQLVPSPQSGQFFAWVVVEGLMLKIPLSIPRVFYINSKVPIDEYFQGKCVNKILPHG 4140
CTIIQLVPSPQSGQFFAWVVVEGLMLKIPLSIPRVFYINSKVPIDEYFQGKCVNKILPHG
Sbjct: 1321 CTIIQLVPSPQSGQFFAWVVVEGLMLKIPLSIPRVFYINSKVPIDEYFQGKCVNKILPHG 1380
Query: 4141 RPCYSLTEACVKIQEDQFKKESKKRAALLADPGVEGIYETKVPLEFSAICQIGCVCKIDN 4320
RPCYSLTEACVKIQEDQFKKESKKRAALLADPGVEGIYETKVPLEFSAICQIGCVCKIDN
Sbjct: 1381 RPCYSLTEACVKIQEDQFKKESKKRAALLADPGVEGIYETKVPLEFSAICQIGCVCKIDN 1440
Query: 4321 KAKHRNTQDGWEVGELHMKTTTECHYLKRSIPLVYLYNSTSTGRAIYVLYCHVSKLMSAV 4500
KAKHRNTQDGWEVGELHMKTTTECHYLKRSIPLVYLYNSTSTGRAIYVLYCHVSKLMSAV
Sbjct: 1441 KAKHRNTQDGWEVGELHMKTTTECHYLKRSIPLVYLYNSTSTGRAIYVLYCHVSKLMSAV 1500
Query: 4501 VVDPFNGNELLPSALERQFRXXXXXXXXXXXXXXGIRFQVHYVDHPEAAKKIIQRAISEY 4680
VVDPFNGNELLPSALERQFR GIRFQVHYVDHPEAAKKIIQRAISEY
Sbjct: 1501 VVDPFNGNELLPSALERQFRDSCLELSLDSLSWDGIRFQVHYVDHPEAAKKIIQRAISEY 1560
Query: 4681 REENCGPTVAVIECPDFTFMKEGIKALDDFPCVRIPFNDDDNSYQPVSWQRPAAKIAMFR 4860
REENCGPTVAVIECPDFTFMKEGIKALDDFPCVRIPFNDDDNSYQPVSWQRPAAKIAMFR
Sbjct: 1561 REENCGPTVAVIECPDFTFMKEGIKALDDFPCVRIPFNDDDNSYQPVSWQRPAAKIAMFR 1620
Query: 4861 CAAAFQWLDRRITQSRYAHVPLGNFGLDWLTFTIDIFLSRALRDQQQVLWVSDNGVPDLG 5040
CAAAFQWLDRRITQSRYAHVPLGNFGLDWLTFTIDIFLSRALRDQQQVLWVSDNGVPDLG
Sbjct: 1621 CAAAFQWLDRRITQSRYAHVPLGNFGLDWLTFTIDIFLSRALRDQQQVLWVSDNGVPDLG 1680
Query: 5041 GINNEEAFFADEVQQTSLVFPGAYRKVSVELKIHNLAVNALLKSNLVNXXXXXXXXXXXQ 5220
GINNEEAFFADEVQQTSLVFPGAYRKVSVELKIHNLAVNALLKSNLVN Q
Sbjct: 1681 GINNEEAFFADEVQQTSLVFPGAYRKVSVELKIHNLAVNALLKSNLVNEMEGGGFMGFEQ 1740
Query: 5221 DVNPRGINSNDNTSFDETTGCAQAFRVLKQLIHSCLTDVRKSKNIYADSILQRLSWWLCS 5400
DVNPRGINSNDNTSFDETTGCAQAFRVLKQLIHSCLTDVRKSKNIYADSILQRLSWWLCS
Sbjct: 1741 DVNPRGINSNDNTSFDETTGCAQAFRVLKQLIHSCLTDVRKSKNIYADSILQRLSWWLCS 1800
Query: 5401 PSSKLHDPALHLMLHKVMQKVFALLLTDLRRLGAIIIYADFSKVIIDTVKFDLSAAKAYC 5580
PSSKLHDPALHLMLHKVMQKVFALLLTDLRRLGAIIIYADFSKVIIDTVKFDLSAAKAYC
Sbjct: 1801 PSSKLHDPALHLMLHKVMQKVFALLLTDLRRLGAIIIYADFSKVIIDTVKFDLSAAKAYC 1860
Query: 5581 ESLLSTVRNRLVSSLLDIHVYDLKSHGLHSFSCHDFCASPLTYNYAGIRADDEISLDEVT 5760
ESLLSTVRNRLVSSLLDIHVYDLKSHGLHSFSCHDFCASPLTYNYAGIRADDEISLDEVT
Sbjct: 1861 ESLLSTVRNRLVSSLLDIHVYDLKSHGLHSFSCHDFCASPLTYNYAGIRADDEISLDEVT 1920
Query: 5761 IEPKWSVARHLPEYIEVWRQNPHSNQCSFSENKKHVATHGPFFLDTDAFHLSWQRDXXXX 5940
IEPKWSVARHLPEYIEVWRQNPHSNQCSFSENKKHVATHGPFFLDTDAFHLSWQRD
Sbjct: 1921 IEPKWSVARHLPEYIEVWRQNPHSNQCSFSENKKHVATHGPFFLDTDAFHLSWQRDFIII 1980
Query: 5941 XXXXXXDPWKFAIENKKGSSESLEAQMIEYLREQIGSTFINMLVKKVDDIMSHMKEINVS 6120
DPWKFAIENKKGSSESLEAQMIEYLREQIGSTFINMLVKKVDDIMSHMKEINVS
Sbjct: 1981 IAKFIFDPWKFAIENKKGSSESLEAQMIEYLREQIGSTFINMLVKKVDDIMSHMKEINVS 2040
Query: 6121 DASRVSGQAPKGDYSLEFIQVISAVLALDQNVQQDVLLKTLFITDFIHKSNLISGNVVLE 6300
DASRVSGQAPKGDYSLEFIQVISAVLALDQNVQQDVLLKTLFITDFIHKSNLISGNVVLE
Sbjct: 2041 DASRVSGQAPKGDYSLEFIQVISAVLALDQNVQQDVLLKTLFITDFIHKSNLISGNVVLE 2100
Query: 6301 TMFTNRAGFFFEWVMRKSLLKYIKVKECAAEAEFLDPGPSFILPNVACSNCDAYRDLDIC 6480
TMFTNRAGFFFEWVMRKSLLKYIKVKECAAEAEFLDPGPSFILPNVACSNCDAYRDLDIC
Sbjct: 2101 TMFTNRAGFFFEWVMRKSLLKYIKVKECAAEAEFLDPGPSFILPNVACSNCDAYRDLDIC 2160
Query: 6481 RDPALLTEKEWSCADTQCGKIYDREQMESSLLEMVRQRERMYHMQDVVCIRCNQVKAAHL 6660
RDPALLTEKEWSCADTQCGKIYDREQMESSLLEMVRQRERMYHMQDVVCIRCNQVKAAHL
Sbjct: 2161 RDPALLTEKEWSCADTQCGKIYDREQMESSLLEMVRQRERMYHMQDVVCIRCNQVKAAHL 2220
Query: 6661 TEQCECSGSFRCKESGSEFSKRMEIFMDIAKRQKFRLLEEYISWIIYGPSY 6813
TEQCECSGSFRCKESGSEFSKRMEIFMDIAKRQKFRLLEEYISWIIYGPSY
Sbjct: 2221 TEQCECSGSFRCKESGSEFSKRMEIFMDIAKRQKFRLLEEYISWIIYGPSY 2271
>ref|NP_180280.1| putative DNA polymerase epsilon catalytic subunit; protein id:
At2g27120.1 [Arabidopsis
thaliana]|gi|3885342|gb|AAC77870.1| putative DNA
polymerase epsilon catalytic subunit [Arabidopsis
thaliana]|gi|25288543|pir||A84669 hypothetical protein
At2g27120 [imported] - Arabidopsis thaliana
Length = 2154
Score = 3448 bits (8940), Expect = 0.0
Identities = 1764/2277 (77%), Positives = 1893/2277 (82%), Gaps = 30/2277 (1%)
Frame = +1
Query: 70 TAEDELESKLGFGLFSEGETRLGWLLTFSSSSWEDRDTGKVYSCVDLYFVTQDGFSFKTK 249
+A DELE+KLGFGLFS+GETRLGWLLTF+SSSWED DTGK +SCVDL+FVTQDG SFKTK
Sbjct: 16 SAADELETKLGFGLFSQGETRLGWLLTFASSSWEDADTGKTFSCVDLFFVTQDGSSFKTK 75
Query: 250 YKFRPYFYAATKDKMXXXXXXXXXXXXXXQVADIEIVEKEDLDLKNHLSGLQKKYLKISF 429
YKFRPY YAATKD M QVADI+IV KEDL LKNHLSGLQKKYLK+SF
Sbjct: 76 YKFRPYLYAATKDNMELEVEAYLRRRYERQVADIQIVHKEDLYLKNHLSGLQKKYLKVSF 135
Query: 430 DTVQQLMEVKRDLLHIVERNQAKFDALEAYESILAGKREQRPQDCLDSIVDLREYDVPYH 609
DTVQQL+EVKRDLLHIVERN AKF+ALEAYESIL+GKREQRPQDCLDS+VDLREYDVPYH
Sbjct: 136 DTVQQLVEVKRDLLHIVERNLAKFNALEAYESILSGKREQRPQDCLDSVVDLREYDVPYH 195
Query: 610 VRFAIDNDVRSGQWYNVSISSTDVILEKRTDLLQRAEVRVCAFDIETTKLPLKFPDAEYD 789
VRFAIDNDVRSGQWYNVSISSTDVILEKRTDLLQRAEVRVCAFDIET KLPLKFPDAEYD
Sbjct: 196 VRFAIDNDVRSGQWYNVSISSTDVILEKRTDLLQRAEVRVCAFDIETVKLPLKFPDAEYD 255
Query: 790 QIMMISYMVDGQGFLIINREVTACVGEDVEDLEYTPKPEFEGYFKVTNVKNEVELLQRWF 969
QIMMISYMVDGQGFLI NRE CVG+D+EDLEYTPKPEFEGYFKVTNV NEVELL++WF
Sbjct: 256 QIMMISYMVDGQGFLITNRE---CVGKDIEDLEYTPKPEFEGYFKVTNVTNEVELLRKWF 312
Query: 970 YHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNEELGFRCDQNQGECRAKFACHLDC 1149
HMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNEELGFRCDQNQGECRAKF CHLDC
Sbjct: 313 SHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNEELGFRCDQNQGECRAKFVCHLDC 372
Query: 1150 FAWVKRDSYLPQGSHGLKAVTKAKLGYDPLEVNPEDMVRFAMEKPQTMASYSVSDAVATY 1329
F+WVKRDSYLPQGS GLKAVTK KLGYDPLEVNPEDMVRFAMEKPQTMASYSVSDAVATY
Sbjct: 373 FSWVKRDSYLPQGSQGLKAVTKVKLGYDPLEVNPEDMVRFAMEKPQTMASYSVSDAVATY 432
Query: 1330 YLYMTYVNPFIFSLATIIPMVPDEVLRKGSGTLCEMLLMVEVSTYLPQAQAYKANVVCPN 1509
YLYMTYV+PF+FSLATIIPMVPDEVLRKGSGTLCEMLLMVE AYKANVVCPN
Sbjct: 433 YLYMTYVHPFVFSLATIIPMVPDEVLRKGSGTLCEMLLMVE---------AYKANVVCPN 483
Query: 1510 KNQADPEKFYQNQLLESETYIGGHVECLESG------------------QLIDNLGRDLE 1635
KNQADPEKFYQ +LLESETYIGGHVECL+SG QLIDNLGRDLE
Sbjct: 484 KNQADPEKFYQGKLLESETYIGGHVECLQSGVFRSDIPTSFKLDASAYQQLIDNLGRDLE 543
Query: 1636 YAITVEGKMRMDSISNYDEVKDEIKEKLEKLRDDPIREEGPLIYHLDVAAMYPNIILTNR 1815
YAITVEGKMRMDS+SN+DEVK+ I+EKLEKLRDDPIREEGPLIYHLDVAAMYPNIILTNR
Sbjct: 544 YAITVEGKMRMDSVSNFDEVKEVIREKLEKLRDDPIREEGPLIYHLDVAAMYPNIILTNR 603
Query: 1816 LQVHLISPPSIVTDEICTACDFNRPGKTCLRKLEWVWRGVTFMGKKSDYYHLKKQIESEF 1995
LQ PPSIVTDE+CTACDFN P KTCLRKLEWVWRGVTF G KS+YYHLKKQIESE
Sbjct: 604 LQ-----PPSIVTDEVCTACDFNGPEKTCLRKLEWVWRGVTFKGNKSEYYHLKKQIESES 658
Query: 1996 VDAGANIMSSKSFLDLPKVDQQSKLKERLKKYCQKAYKRVLDKPITEVREAGICMRENPF 2175
VDAGAN+ SSK FLDLPKV+QQSKLKERLKKYCQKAY RVLDKPITEVREAGICMRENPF
Sbjct: 659 VDAGANMQSSKPFLDLPKVEQQSKLKERLKKYCQKAYSRVLDKPITEVREAGICMRENPF 718
Query: 2176 YVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNSIKIQEAQDMVVVYDSLQLAHKCILN 2355
YVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGN IKIQEA DMVVVYDSLQLAHKCILN
Sbjct: 719 YVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNLIKIQEAHDMVVVYDSLQLAHKCILN 778
Query: 2356 SFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDTDGIWCCLPGSFP 2535
SFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDTDGIWC LPGSFP
Sbjct: 779 SFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDTDGIWCALPGSFP 838
Query: 2536 ENFTFKTIDMKKLTISYPCVMLNVDVAKNNTNDQYQTLVDPVRKTYKSHSECSIEFEVDG 2715
ENFTFKTIDMKK TISYPCV+LNVDVAKNN+NDQYQTLVDPVRKTY S SECSIEFEVDG
Sbjct: 839 ENFTFKTIDMKKFTISYPCVILNVDVAKNNSNDQYQTLVDPVRKTYNSRSECSIEFEVDG 898
Query: 2716 PYKAMIIPASKEEGILIKKRYAVFNHDGTLAELKGFEIKRRGELKLIKVFQAELFDKFLH 2895
PYKAMIIPASKEEGILIKKRYAVFNHDGT+AELKGFE+KRRGELKLIKVFQAELFDKFLH
Sbjct: 899 PYKAMIIPASKEEGILIKKRYAVFNHDGTIAELKGFEMKRRGELKLIKVFQAELFDKFLH 958
Query: 2896 GSTLEECYSAVAAVADRWLDLLDVCEISCFFWVIYLIGFLSHFLQNQGKDIADSELLDYI 3075
GSTLEECYSAVAAVA+RWLDL L+ QGKDIADSELLDYI
Sbjct: 959 GSTLEECYSAVAAVANRWLDL----------------------LEGQGKDIADSELLDYI 996
Query: 3076 SESSTMSKSLADYGEQKSCAVTTAKRLAEFLGVTMVKDKGLRCQYIVACEPKGTPVSERA 3255
SESSTMSKSLADYG+QKSCAVTTAKRLA+FLG TMVKDKGLRCQYIVA EP+GTPVSERA
Sbjct: 997 SESSTMSKSLADYGQQKSCAVTTAKRLADFLGDTMVKDKGLRCQYIVAREPEGTPVSERA 1056
Query: 3256 VPVAIFTTNPEVMKFHLRKWCKTSSDVGIRLIIDWSYYKQRLSSAIQKVITIPAAMQKVA 3435
VPVAIF T+ KF+L+KWCK SS GIR IIDW YYKQRL SAIQKVITIPAAMQKVA
Sbjct: 1057 VPVAIFQTDDPEKKFYLQKWCKISSYTGIRSIIDWMYYKQRLHSAIQKVITIPAAMQKVA 1116
Query: 3436 NPVPRVLHPDWLHKKVREKDDKFRQRKLVDMFSSANKDVVLDTDLPVTKDN-VEDIEDFC 3612
NPV RV HP WL KKV DKFRQ K+VDMFSSANK D T+DN V DIE+FC
Sbjct: 1117 NPVLRVRHPYWLEKKV---CDKFRQGKIVDMFSSANK------DHSTTQDNVVADIEEFC 1167
Query: 3613 KENRPSVKGPKPIARSYEVNKKQSECEQQESWDTEFHDISFQNIDKSVNYQGWLELKKRK 3792
KENRPSVKGPKP+ARS+EV++ SE +QQESWD EFHDIS QN+DK+V+YQGWLEL+KRK
Sbjct: 1168 KENRPSVKGPKPVARSFEVDRNHSEGKQQESWDPEFHDISLQNVDKNVDYQGWLELEKRK 1227
Query: 3793 WKVTLEKKKKRRLGDLRSSNQVDTHEINQKVGQGRGGVGSYFRRPEEALTSSHWQVCTII 3972
WK+TL KKKRR DL+ NQ+D H+IN+KV +GR GVGSYFRRPEEALTSS+ Q II
Sbjct: 1228 WKMTLTNKKKRRFDDLKPCNQIDAHKINKKVCKGRVGVGSYFRRPEEALTSSYLQ---II 1284
Query: 3973 QLVPSPQSGQFFAWVVVEGLMLKIPLSIPRVFYINSKVPIDEYFQGKCVNKILPHGRPCY 4152
QLV SPQSGQFFAWVVVEGLMLKIPL+IPRVFYINSK I F GKC+NKILPHG+PCY
Sbjct: 1285 QLVQSPQSGQFFAWVVVEGLMLKIPLTIPRVFYINSKASIAGNFTGKCINKILPHGKPCY 1344
Query: 4153 SLTEA----------CVKIQEDQFKKESKKRAALLADPGVEGIYETKVPLEFSAICQIGC 4302
+L EA V IQEDQF KESKK AALLADP +EGIYETK+PLEFSAICQIGC
Sbjct: 1345 NLMEARHLHNTHILLLVNIQEDQFIKESKKLAALLADPEIEGIYETKMPLEFSAICQIGC 1404
Query: 4303 VCKIDNKAKHRNTQDGWEVGELHMKTTTECHYLKRSIPLVYLYNSTSTGRAIYVLYCHVS 4482
VCKI++ AKHRNTQDGW++GELH TTTEC YL+ SIPLVYLY+STSTGRA+YVLYCH S
Sbjct: 1405 VCKIEDTAKHRNTQDGWKLGELHRITTTECRYLENSIPLVYLYHSTSTGRAVYVLYCHAS 1464
Query: 4483 KLMSAVVVDPFNGNELLPSALERQFRXXXXXXXXXXXXXXGIRFQVHYVDHPEAAKKIIQ 4662
KLMS VVV+P+ ELL SALERQFR GI FQV YVDHPEAA K +Q
Sbjct: 1465 KLMSVVVVNPYGDKELLSSALERQFRDRCQELSPEPFSWDGILFQVEYVDHPEAATKFLQ 1524
Query: 4663 RAISEYREENCGPTVAVIECPDFTFMKEGIKALDDFPCVRIPFNDDDNSYQPVSWQRPAA 4842
+A+ EYREENCG TVAVIECPDF KEG+KAL+DFPCVRIPFNDDDNSYQPVSWQRPAA
Sbjct: 1525 KALCEYREENCGATVAVIECPDFNTTKEGVKALEDFPCVRIPFNDDDNSYQPVSWQRPAA 1584
Query: 4843 KIAMFRCAAAFQWLDRRITQSRYAHVPLGNFGLDWLTFTIDIFLSRALRDQQQVLWVSDN 5022
KIA+ RCA+A QWLDRRI QSRYAHVPLGNFG DWLTFT+DIFLSRALRDQQQVLWVSDN
Sbjct: 1585 KIAVLRCASAIQWLDRRIAQSRYAHVPLGNFGRDWLTFTVDIFLSRALRDQQQVLWVSDN 1644
Query: 5023 GVPDLGGINNEEAFFADEVQQTSLVFPGAYRKVSVELKIHNLAVNALLKSNLVNXXXXXX 5202
GVPDLG INNEE F ADE+Q+TSL+FPGAYRKVSVELK+H LAVNALLKS+LV+
Sbjct: 1645 GVPDLGDINNEETFLADELQETSLLFPGAYRKVSVELKVHRLAVNALLKSDLVSEMEGGG 1704
Query: 5203 XXXXXQDVNPRGINSNDNTSFDETTGCAQAFRVLKQLIHSCLTDVRKSKNIYADSILQRL 5382
VN RG + NDN SFDE GCAQAFRVLKQLI L D S NIYADSILQ L
Sbjct: 1705 FL----GVNSRGSSLNDNGSFDENNGCAQAFRVLKQLIKRLLHDACNSGNIYADSILQHL 1760
Query: 5383 SWWLCSPSSKLHDPALHLMLHKVMQKVFALLLTDLRRLGAIIIYADFSKVIIDTVKFDLS 5562
SWWL SPSSKLHDPALHLMLHKVMQKVFALLLTDLRRLGAIIIYADFSKVIIDT KFDLS
Sbjct: 1761 SWWLRSPSSKLHDPALHLMLHKVMQKVFALLLTDLRRLGAIIIYADFSKVIIDTGKFDLS 1820
Query: 5563 AAKAYCESLLSTVRNRLVSSLLDIHVYDLKSHGLHSFSCHDFCASPLTYNYAGIRA-DDE 5739
AAK YCESLL+ + +R + L+ + H HS D +NYAGIRA DE
Sbjct: 1821 AAKTYCESLLTVMGSRDIFKLILLE----PVHYWHSLLFMD------QHNYAGIRATGDE 1870
Query: 5740 ISLDEVTIEPKWSVARHLPEYIEVWRQNPHSNQCSFSENKKHVATHGPFFLDTDAFHLSW 5919
IS +EVTIEPKWSVARHLPEYI
Sbjct: 1871 ISGNEVTIEPKWSVARHLPEYI-------------------------------------- 1892
Query: 5920 QRDXXXXXXXXXXDPWKFAIENKKGSSESLEAQMIEYLREQIGSTFINMLVKKVDDIMSH 6099
Q+D PWKFA+E K+GS+ESLEA+M+EYL+EQIG+ FI+M+V+K+ +I SH
Sbjct: 1893 QKDFIIIVATFIFGPWKFALEKKRGSAESLEAEMVEYLKEQIGTRFISMIVEKIGNIRSH 1952
Query: 6100 MKEINVSDASRVSGQAPKGDYSLEFIQVISAVLALDQNVQQDVLLKTLFITDFIHKSNLI 6279
+K+INVSDAS SGQAPKGDY+ EFIQ+I+AVLALDQNVQQDVL
Sbjct: 1953 IKDINVSDASWASGQAPKGDYTFEFIQIITAVLALDQNVQQDVL---------------- 1996
Query: 6280 SGNVVLETMFTNRAGFFFEWVMRKSLLKYIKVKECAAEAEFLDPGPSFILPNVACSNCDA 6459
VMRK LLKYIKVKECAAEAEF+DPGPSFILPNVACSNC A
Sbjct: 1997 --------------------VMRKILLKYIKVKECAAEAEFIDPGPSFILPNVACSNCGA 2036
Query: 6460 YRDLDICRDPALLTEKEWSCADTQCGKIYDREQMESSLLEMVRQRERMYHMQDVVCIRCN 6639
YRDLD CRD ALLTEKEWSCAD QC KIYD+EQ+ESS+++MVRQRERMY +QD+VC RCN
Sbjct: 2037 YRDLDFCRDSALLTEKEWSCADPQCVKIYDKEQIESSIIQMVRQRERMYQLQDLVCNRCN 2096
Query: 6640 QVKAAHLTEQCECSGSFRCKESGSEFSKRMEIFMDIAKRQKFRLLEEYISWIIYGPS 6810
QVKAAHLTEQCECSGSFRCKESGS+F KR+EIF+DIAKRQKFRLLEE ISWI++ S
Sbjct: 2097 QVKAAHLTEQCECSGSFRCKESGSDFHKRIEIFLDIAKRQKFRLLEECISWILFATS 2153
>ref|XP_194234.1| polymerase (DNA directed), epsilon [Mus musculus]
Length = 2283
Score = 1586 bits (4107), Expect = 0.0
Identities = 943/2342 (40%), Positives = 1337/2342 (56%), Gaps = 102/2342 (4%)
Frame = +1
Query: 79 DELESKLGFGLFSEGETRLGWLLTFSSSSWEDRDTGKVYSCVDLYFVTQDGFSFKTKYKF 258
D+++ + GF E R GWL+ + D D ++ S VD YF+ DG FK +
Sbjct: 42 DKMDLRFGFERLKEPGERTGWLINMHPTEILDEDK-RLVSAVDYYFIQDDGSRFKVALPY 100
Query: 259 RPYFYAATKDKMXXXXXXXXXXXXXXQVADIEIVEKEDLDLKNHLSGLQKKYLKISFDTV 438
PYFY A + ++A +E V KEDLDL NHL GL++ Y+K+SF TV
Sbjct: 101 MPYFYIAARKGCDREVSSFLSKKFQGKIAKLENVPKEDLDLPNHLVGLKRSYIKLSFHTV 160
Query: 439 QQLMEVKRDLLHIVERNQAKFDALEAYESILAG------------KREQRPQDCLDSIVD 582
+ L++V++++ V++N+ + A + Y ++L+ + ++ D LD+IVD
Sbjct: 161 EDLVKVRKEISPAVKKNREQDHASDEYTTMLSSILQGGSVITDEDETSKKIADQLDNIVD 220
Query: 583 LREYDVPYHVRFAIDNDVRSGQWYNVSI--SSTDVILEKRTDLLQRAEVRVCAFDIETTK 756
+REYDVPYH+R +ID + WYNV ++ V + +R DL++R + V AFDIETTK
Sbjct: 221 MREYDVPYHIRLSIDLRIHVAHWYNVRFRGNAFPVEITRRDDLVERPDPVVLAFDIETTK 280
Query: 757 LPLKFPDAEYDQIMMISYMVDGQGFLIINREVTACVGEDVEDLEYTPKPEFEGYFKVTNV 936
LPLKFPDAE DQIMMISYM+DGQG+LI NRE+ V ED+ED E+TPKPE+EG F V N
Sbjct: 281 LPLKFPDAETDQIMMISYMIDGQGYLITNREI---VSEDIEDFEFTPKPEYEGPFCVFNE 337
Query: 937 KNEVELLQRWFYHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNEELGFRCDQNQGE 1116
+EV L+QRWF H+QE KP I VTYNGDFFDWPF+E RA+ HG+ M +E+GF+ D +QGE
Sbjct: 338 PDEVHLIQRWFEHIQETKPTIMVTYNGDFFDWPFVEARAAIHGLSMYQEIGFQKD-SQGE 396
Query: 1117 CRAKFACHLDCFAWVKRDSYLPQGSHGLKAVTKAKLGYDPLEVNPEDMVRFAMEKPQTMA 1296
+A H+DC WVKRDSYLP GSH LKA KAKLGYDP+E++PEDM R A E+PQT+A
Sbjct: 397 YKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLA 456
Query: 1297 SYSVSDAVATYYLYMTYVNPFIFSLATIIPMVPDEVLRKGSGTLCEMLLMVEVSTYLPQA 1476
+YSVSDAVATYYLYM YV+PFIF+L TIIPM PDEVLRKGSGTLCE LLMV
Sbjct: 457 TYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMV--------- 507
Query: 1477 QAYKANVVCPNKNQADPEKFYQN-QLLESETYIGGHVECLESGQ---------------- 1605
QA+ AN++ PNK + + K + +L++ETY+GGHVE LESG
Sbjct: 508 QAFHANIIFPNKQEQEFNKLTDDGHMLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAF 567
Query: 1606 --LIDNLGRDLEYAITVEGKMRMDSISNYDEVKDEIKEKLEKLRDDPIREEGPLIYHLDV 1779
L+ + + + +AI E K+ ++ +N+ EV ++IK KL L+D P R E PLIYHLDV
Sbjct: 568 DFLLQRVEKTMRHAIEEEEKVPVEQATNFQEVCEQIKTKLTSLKDVPNRIECPLIYHLDV 627
Query: 1780 AAMYPNIILTNRLQVHLISPPSIVTDEICTACDFNRPGKTCLRKLEWVWRGVTFMGKKSD 1959
AMYPNIILTNRLQ P +IV + C ACDFN+PG +C RK+ W WRG +S+
Sbjct: 628 GAMYPNIILTNRLQ-----PSAIVDEATCAACDFNKPGASCQRKMAWQWRGEFMPASRSE 682
Query: 1960 YYHLKKQIESEFVDAGANIMSSKSFLDLPKVDQQSKLKERLKKYCQKAYKRVLDKPITEV 2139
Y+ ++ Q+ESE +++F +L + +Q K RL YC+KAYK++ + E
Sbjct: 683 YHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHVTKVEE- 741
Query: 2140 REAGICMRENPFYVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNSIKIQEAQDMVVVY 2319
R IC REN FYVDTVR+FRDRRYE+K L+KVWK KLS A G++ +++ ++M ++Y
Sbjct: 742 RLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDASEVKRCKNMEILY 801
Query: 2320 DSLQLAHKCILNSFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDT 2499
DSLQLAHKCILNSFYGYVMRKGARWYSMEMAG+V +TGA II AR LIE+IG+PLELDT
Sbjct: 802 DSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDT 861
Query: 2500 DGIWCCLPGSFPENFTFKTIDMK--KLTISYPCVMLNVDVAKNNTNDQYQTLVDPVRKTY 2673
DGIWC LP SFPENF KT + K KLTISYP MLN+ V + TN QYQ L +P TY
Sbjct: 862 DGIWCVLPNSFPENFVIKTTNAKKPKLTISYPGAMLNIMVKEGFTNHQYQELTEPSSLTY 921
Query: 2674 KSHSECSIEFEVDGPYKAMIIPASKEEGILIKKRYAVFNHDGTLAELKGFEIKRRGELKL 2853
+HSE SI FEVDGPY AMI+PASKEEG +KKRYAVFN DG+LAELKGFE+KRRGEL+L
Sbjct: 922 VTHSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQL 981
Query: 2854 IKVFQAELFDKFLHGSTLEECYSAVAAVADRWLDLLDVCEISCFFWVIYLIGFLSHFLQN 3033
IK+FQ+ +F+ FL GSTLEE Y +VA VAD WLD+ L +
Sbjct: 982 IKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDV----------------------LYS 1019
Query: 3034 QGKDIADSELLDYISESSTMSKSLADYGEQKSCAVTTAKRLAEFLGVTMVKDKGLRCQYI 3213
+ ++ DSEL + ISE+ +MS+ L DYGEQKS +++TAKRLAEFLG MVKD GL C+YI
Sbjct: 1020 KAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYI 1079
Query: 3214 VACEPKGTPVSERAVPVAIFTTNPEVMKFHLRKWCKTSS--DVGIRLIIDWSYYKQRLSS 3387
++ +P+G+PV+ERA+P+AIF P V K LRKW K+SS D IR I+DW YY +RL S
Sbjct: 1080 ISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGS 1139
Query: 3388 AIQKVITIPAAMQKVANPVPRVLHPDWLHKKVREKDDKFRQRKLVDMFSSANKDVVL--- 3558
AIQK+ITIPAA+Q+V NPVPRV HPDWLHKK+ EK+D ++Q+K+ ++F K ++
Sbjct: 1140 AIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDIYKQKKISELFVLEGKRQIVMAQ 1199
Query: 3559 --DTDLPVTKDNVEDIEDFCKENRPSVKGPKPIARSYEVNKKQSECEQQESWDTEFHDIS 3732
+ L + ++EDI K + +V R +E K+ + W
Sbjct: 1200 ASENSLSLCTPDMEDI-GLTKPHHSTVPVATKRKRVWETQKESQDIALTVPWQEVLGQPP 1258
Query: 3733 FQNIDKSVNYQGWLELKKRKWKVTLEKKKKRRLGDLRSSNQVDTHEINQKVGQGR----G 3900
+ + WL+ K+KW++ +++ LR ++++ E ++G R
Sbjct: 1259 SLGTTQE-EWLVWLQFHKKKWQLQAQQRLA-----LRKKQRLESAEDMPRLGPIREGPST 1312
Query: 3901 GVGSYFRRPEEALTSSHWQVCTIIQLVPSPQSGQFFAWVVVEGLMLKIPLSIPRVFYINS 4080
G+GS+ RR ++ WQ IIQ+ + Q+G F W ++ + I LSIPRVFY+N
Sbjct: 1313 GLGSFLRRTARSIMDLPWQ---IIQISETRQAGLFRLWAIIGNDLHCIKLSIPRVFYVNQ 1369
Query: 4081 KVPIDEYFQG-KCVNKILPHGRPCYSLTEACVKIQEDQFKKESKKRAALLADPGVEGIYE 4257
+V E + VN+ LP Y+L E + ED +++ + L+ P +EG+YE
Sbjct: 1370 RVAKAEDGPAYRKVNRALPRSNIVYNLYE--YSVPEDMYQEHINEINTELSVPDIEGVYE 1427
Query: 4258 TKVPLEFSAICQIGCVCKIDNKAKHRNTQDGWE-----VGELHMKTTTECHYLK-RSIPL 4419
T+VPL F A+ Q+GCVC + NK R+ GWE + L M++ + YL+ SI
Sbjct: 1428 TQVPLLFRALVQLGCVCVV-NKQLTRHL-SGWEAETFALEHLEMRSLAQFSYLEPGSIRH 1485
Query: 4420 VYLYNSTSTGRAIYVLYCHVSKLMSAVVVDPFNGNEL--LPSALERQFRXXXXXXXXXXX 4593
+YLY+ T +A++ ++ + S V+D N++ L + +
Sbjct: 1486 IYLYHHTQGHKALFGVFIPSQRRASVFVLDTVRSNQMPGLSALYSSEHSLLLDKVDPKLL 1545
Query: 4594 XXXGIRFQVHYVDHPEAAKKIIQRAISEYREENCGPT-VAVIECPDFTFMKEGIKALDDF 4770
F+V + + + IQR + Y+EE GPT +AV + + I L++F
Sbjct: 1546 PPPKHTFEVRAETNLKTICRAIQRFLLAYKEERRGPTLIAVQSSWELCRLTSEIPVLEEF 1605
Query: 4771 PCVRIPFNDDDNSYQPVSWQRPAAKIAMFRCAAAFQWLDRRITQSRYAHVPLGNFGLDWL 4950
P V I D SY + WQR A+ + L + SRY H+P+GN D
Sbjct: 1606 PLVPIRV-ADKISYAVLDWQRHGARRMIRHYLNLDLCLSQAFEMSRYFHIPVGNLPEDIS 1664
Query: 4951 TFTIDIFLSRALRDQQQVLWVSDNGVPDLGG---INNEEAFFADEVQQTSLVFPGAYRKV 5121
TF D+F +R L+ +LW+S PDLGG +N D+ + G Y V
Sbjct: 1665 TFGSDLFFARHLQHHNHLLWLSPTSRPDLGGKEADDNRLVMEFDDRATVEINSSGCYSTV 1724
Query: 5122 SVELKIHNLAVNALLKSNLVNXXXXXXXXXXXQDVNPRG-----INSNDNTS----FDET 5274
VEL I NLAVN +L+S+ VN DV + + N S +DET
Sbjct: 1725 CVELDIQNLAVNTILQSHHVNDMEGAGSMGISFDVIQQASLEDMVTGNQAASALANYDET 1784
Query: 5275 TGCAQAFRVLKQLIHSCLTDVRKSKNIYADSILQRLSWWLCSPSSKLHDPALHLMLHKVM 5454
C+ FR+LK ++ + ++ + NIYAD+ + WL SP S LHDPALH LH +M
Sbjct: 1785 ALCSSTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLQSPCSLLHDPALHRTLHNMM 1844
Query: 5455 QKVFALLLTDLRRLGAIIIYADFSKVIIDTVKFDLSAAKAYCESLLSTVRNRLVSSLLDI 5634
+K+F L+ + +RLG+ ++YA+F+++I+ T K + A AY E + +++ ++ + L I
Sbjct: 1845 KKLFLQLIAEFKRLGSSVVYANFNRIILCTKKRRIEDALAYVEYITNSIHSKEIFHSLTI 1904
Query: 5635 HVYDLKSHGLHSFS-CHDFCASPLTYNYAGIRADDEISLDEVTIEPKWSVARHLPEYIEV 5811
SFS C +F NY GI+ S+ ++ + S AR + E
Sbjct: 1905 -----------SFSRCWEFLLWMDPSNYGGIKGKVPSSIHCGQVKEQDSQAREETDEEEE 1953
Query: 5812 WRQNPHSNQC-------SFSENKKHVATHGP--------FFLDTDAFHLSWQRDXXXXXX 5946
++ + EN ++ P F + A+ ++ +
Sbjct: 1954 DKEKDEEEEGMGESEVEDLLENNWNILQFLPQAASCQSYFLMIVSAYIVAVYQSMKEELR 2013
Query: 5947 XXXXDPWKFAIENKKGSSESLEAQ--------MI----EYLREQIGSTFINMLVKKVDDI 6090
P ++ K S S E++ MI +Y+ ++ +F + K +
Sbjct: 2014 HSA--PGSTPVKRKGASQFSQESEGATGSLPGMITFSQDYVANELTQSFFTITQKIQKKV 2071
Query: 6091 MSHMKEINVSDASRV--SGQAPKGDYSLEFIQVISAVLALDQNVQQDVLLKTLFITDFIH 6264
S+ V + +LEFI+ + VL+LD N IT+ ++
Sbjct: 2072 TGSRNTTEPSEMFPVLPGSHLLLNNPALEFIKYVCKVLSLDTN-----------ITNQVN 2120
Query: 6265 KSNLISGNVVLETMFTNRAGFFFEWVMRKSLLKYIKVKECAAEAEFLDPGPSFILPNVAC 6444
K N + LL+ + V E + EA+F DP S++LP V C
Sbjct: 2121 KLN-------------------------RDLLRLVDVGEFSEEAQFRDPCHSYVLPEVIC 2155
Query: 6445 SNCDAYRDLDICRDPALLTE----KEWSCADTQCGKIYDREQMESSLLEMVRQRERMYHM 6612
+C+ RDLD+C+D + + +W C++ C YD +ES+L+E ++++ + +
Sbjct: 2156 HSCNFCRDLDLCKDSSFSQDGAILPQWLCSN--CQAPYDSSAIESALVEALQRKLMAFTL 2213
Query: 6613 QDVVCIRCNQVKAAHLTEQCECSGSFRCKESGSEFSKRMEIFMDIAKRQKFRLLEEYISW 6792
QD+VC++C +K H+ C C+G F F +++ IF +IAK L+E I W
Sbjct: 2214 QDLVCLKCRGMKETHMPVYCSCAGDFTLTIRTEVFMEQIRIFQNIAKYYSMSYLQETIEW 2273
Query: 6793 II 6798
++
Sbjct: 2274 LL 2275
>gb|AAD46482.1| DNA polymerase epsilon catalytic subunit [Mus
musculus]|gi|6755124|ref|NP_035262.1| polymerase (DNA
directed), epsilon; pol-epsilon; DNA polymerase epsilon
[Mus musculus]|gi|17367197|sp|Q9WVF7|DPOE_MOUSE DNA
polymerase epsilon, catalytic subunit A (DNA polymerase
II subunit A)
Length = 2283
Score = 1583 bits (4100), Expect = 0.0
Identities = 941/2342 (40%), Positives = 1336/2342 (56%), Gaps = 102/2342 (4%)
Frame = +1
Query: 79 DELESKLGFGLFSEGETRLGWLLTFSSSSWEDRDTGKVYSCVDLYFVTQDGFSFKTKYKF 258
D+++ + GF E R GWL+ + D D ++ S VD YF+ DG FK +
Sbjct: 42 DKMDLRFGFERLKEPGERTGWLINMHPTEILDEDK-RLVSAVDYYFIQDDGSRFKVALPY 100
Query: 259 RPYFYAATKDKMXXXXXXXXXXXXXXQVADIEIVEKEDLDLKNHLSGLQKKYLKISFDTV 438
PYFY A + ++A +E V KEDLDL NHL GL++ Y+K+SF TV
Sbjct: 101 MPYFYIAARKGCDREVSSFLSKKFQGKIAKLENVPKEDLDLPNHLVGLKRSYIKLSFHTV 160
Query: 439 QQLMEVKRDLLHIVERNQAKFDALEAYESILAG------------KREQRPQDCLDSIVD 582
+ L++V++++ V++N+ + A + Y ++L+ + ++ D LD+IVD
Sbjct: 161 EDLVKVRKEISPAVKKNREQDHASDEYTTMLSSILQGGSVITDEDETSKKIADQLDNIVD 220
Query: 583 LREYDVPYHVRFAIDNDVRSGQWYNVSI--SSTDVILEKRTDLLQRAEVRVCAFDIETTK 756
+REYDVPYH+R +ID + WYNV ++ V + +R DL++R + V AFDIETTK
Sbjct: 221 MREYDVPYHIRLSIDLRIHVAHWYNVRFRGNAFPVEITRRDDLVERPDPVVLAFDIETTK 280
Query: 757 LPLKFPDAEYDQIMMISYMVDGQGFLIINREVTACVGEDVEDLEYTPKPEFEGYFKVTNV 936
LPL FPDAE DQIMMISYM+DGQG+LI NRE+ V ED+ED E+TPKPE+EG F V N
Sbjct: 281 LPLTFPDAETDQIMMISYMIDGQGYLITNREI---VSEDIEDFEFTPKPEYEGPFCVFNE 337
Query: 937 KNEVELLQRWFYHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNEELGFRCDQNQGE 1116
+EV L+QRWF H+QE KP I VTYNGDFFDWPF+E RA+ HG+ M +E+GF+ D +QGE
Sbjct: 338 PDEVHLIQRWFEHIQETKPTIMVTYNGDFFDWPFVEARAAIHGLSMYQEIGFQKD-SQGE 396
Query: 1117 CRAKFACHLDCFAWVKRDSYLPQGSHGLKAVTKAKLGYDPLEVNPEDMVRFAMEKPQTMA 1296
+A H+DC WVKRDSYLP GSH LKA KAKLGYDP+E++PEDM R A E+PQT+A
Sbjct: 397 YKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLA 456
Query: 1297 SYSVSDAVATYYLYMTYVNPFIFSLATIIPMVPDEVLRKGSGTLCEMLLMVEVSTYLPQA 1476
+YSVSDAVATYYLYM YV+PFIF+L TIIPM PDEVLRKGSGTLCE LLMV
Sbjct: 457 TYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMV--------- 507
Query: 1477 QAYKANVVCPNKNQADPEKFYQN-QLLESETYIGGHVECLESGQ---------------- 1605
QA+ AN++ PNK + + K + +L++ETY+GGHVE LESG
Sbjct: 508 QAFHANIIFPNKQEQEFNKLTDDGHVLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAF 567
Query: 1606 --LIDNLGRDLEYAITVEGKMRMDSISNYDEVKDEIKEKLEKLRDDPIREEGPLIYHLDV 1779
L+ + + + +AI E K+ ++ +N+ EV ++IK KL L+D P R E PLIYHLDV
Sbjct: 568 DFLLQRVEKTMRHAIEEEEKVPVEQATNFQEVCEQIKTKLTSLKDVPNRIECPLIYHLDV 627
Query: 1780 AAMYPNIILTNRLQVHLISPPSIVTDEICTACDFNRPGKTCLRKLEWVWRGVTFMGKKSD 1959
AMYPNIILTNRLQ P +IV + C ACDFN+PG +C RK+ W WRG +S+
Sbjct: 628 GAMYPNIILTNRLQ-----PSAIVDEATCAACDFNKPGASCQRKMAWQWRGEFMPASRSE 682
Query: 1960 YYHLKKQIESEFVDAGANIMSSKSFLDLPKVDQQSKLKERLKKYCQKAYKRVLDKPITEV 2139
Y+ ++ Q+ESE +++F +L + +Q K RL YC+KAYK++ + E
Sbjct: 683 YHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHVTKVEE- 741
Query: 2140 REAGICMRENPFYVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNSIKIQEAQDMVVVY 2319
R IC REN FYVDTVR+FRDRRYE+K L+KVWK KLS A G++ +++ ++M ++Y
Sbjct: 742 RLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDASEVKRCKNMEILY 801
Query: 2320 DSLQLAHKCILNSFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDT 2499
DSLQLAHKCILNSFYGYVMRKGARWYSMEMAG+V +TGA II AR LIE+IG+PLELDT
Sbjct: 802 DSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDT 861
Query: 2500 DGIWCCLPGSFPENFTFKTIDMK--KLTISYPCVMLNVDVAKNNTNDQYQTLVDPVRKTY 2673
DGIWC LP SFPENF KT + K KLTISYP MLN+ V + TN QYQ L +P TY
Sbjct: 862 DGIWCVLPNSFPENFVIKTTNAKKPKLTISYPGAMLNIMVKEGFTNHQYQELTEPSSLTY 921
Query: 2674 KSHSECSIEFEVDGPYKAMIIPASKEEGILIKKRYAVFNHDGTLAELKGFEIKRRGELKL 2853
+HSE SI FEVDGPY AMI+PASKEEG +KKRYAVFN DG+LAELKGFE+KRRGEL+L
Sbjct: 922 VTHSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQL 981
Query: 2854 IKVFQAELFDKFLHGSTLEECYSAVAAVADRWLDLLDVCEISCFFWVIYLIGFLSHFLQN 3033
IK+FQ+ +F+ FL GSTLEE Y +VA VAD WLD+ L +
Sbjct: 982 IKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDV----------------------LYS 1019
Query: 3034 QGKDIADSELLDYISESSTMSKSLADYGEQKSCAVTTAKRLAEFLGVTMVKDKGLRCQYI 3213
+ ++ DSEL + ISE+ +MS+ L DYGEQKS +++TAKRLAEFLG MVKD GL C+YI
Sbjct: 1020 KAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYI 1079
Query: 3214 VACEPKGTPVSERAVPVAIFTTNPEVMKFHLRKWCKTSS--DVGIRLIIDWSYYKQRLSS 3387
++ +P+G+PV+ERA+P+AIF P V K LRKW K+SS D IR I+DW YY +RL S
Sbjct: 1080 ISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGS 1139
Query: 3388 AIQKVITIPAAMQKVANPVPRVLHPDWLHKKVREKDDKFRQRKLVDMFSSANKDVVL--- 3558
AIQK+ITIPAA+Q+V NPVPRV HPDWLHKK+ EK+D ++Q+K+ ++F K ++
Sbjct: 1140 AIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDIYKQKKISELFVLEGKRQIVMAQ 1199
Query: 3559 --DTDLPVTKDNVEDIEDFCKENRPSVKGPKPIARSYEVNKKQSECEQQESWDTEFHDIS 3732
+ L + ++EDI K + +V R +E K+ + W
Sbjct: 1200 ASENSLSLCTPDMEDI-GLTKPHHSTVPVATKRKRVWETQKESQDIALTVPWQEVLGQPP 1258
Query: 3733 FQNIDKSVNYQGWLELKKRKWKVTLEKKKKRRLGDLRSSNQVDTHEINQKVGQGR----G 3900
+ + WL+ K+KW++ +++ LR ++++ E ++G R
Sbjct: 1259 SLGTTQE-EWLVWLQFHKKKWQLQAQQRLA-----LRKKQRLESAEDMPRLGPIREGPST 1312
Query: 3901 GVGSYFRRPEEALTSSHWQVCTIIQLVPSPQSGQFFAWVVVEGLMLKIPLSIPRVFYINS 4080
G+GS+ R+ ++ WQ IIQ+ + Q+G F W ++ + I LSIPRVFY+N
Sbjct: 1313 GLGSFLRKTARSIMDLPWQ---IIQISETRQAGLFRLWAIIGNDLHCIKLSIPRVFYVNQ 1369
Query: 4081 KVPIDEYFQG-KCVNKILPHGRPCYSLTEACVKIQEDQFKKESKKRAALLADPGVEGIYE 4257
+V E + VN+ LP Y+L E + ED +++ + L+ P +EG+YE
Sbjct: 1370 RVAKAEDGPAYRKVNRALPRSNIVYNLYE--YSVPEDMYQEHINEINTELSVPDIEGVYE 1427
Query: 4258 TKVPLEFSAICQIGCVCKIDNKAKHRNTQDGWE-----VGELHMKTTTECHYLK-RSIPL 4419
T+VPL F A+ Q+GCVC + NK R+ GWE + L M++ + YL+ SI
Sbjct: 1428 TQVPLLFRALVQLGCVCVV-NKQLTRHL-SGWEAETFALEHLEMRSLAQFSYLEPGSIRH 1485
Query: 4420 VYLYNSTSTGRAIYVLYCHVSKLMSAVVVDPFNGNEL--LPSALERQFRXXXXXXXXXXX 4593
+YLY+ T +A++ ++ + S V+D N++ L + +
Sbjct: 1486 IYLYHHTQGHKALFGVFIPSQRRASVFVLDTVRSNQMPGLSALYSSEHSLLLDKVDPKLL 1545
Query: 4594 XXXGIRFQVHYVDHPEAAKKIIQRAISEYREENCGPT-VAVIECPDFTFMKEGIKALDDF 4770
F+V + E + IQR + Y+EE GPT +AV + + I L++F
Sbjct: 1546 PPPKHTFEVRAETNLETICRAIQRFLLAYKEERRGPTLIAVQSSWELCRLTSEIPVLEEF 1605
Query: 4771 PCVRIPFNDDDNSYQPVSWQRPAAKIAMFRCAAAFQWLDRRITQSRYAHVPLGNFGLDWL 4950
P V I D SY + WQR A+ + L + SRY H+P+GN D
Sbjct: 1606 PLVPIRV-ADKISYAVLDWQRHGARRMIRHYLNLDLCLSQAFEMSRYFHIPVGNLPEDIS 1664
Query: 4951 TFTIDIFLSRALRDQQQVLWVSDNGVPDLGG---INNEEAFFADEVQQTSLVFPGAYRKV 5121
TF D+F +R L+ +LW+S PDLGG +N D+ + G Y V
Sbjct: 1665 TFGSDLFFARHLQHHNHLLWLSPTSRPDLGGKEADDNRLVMEFDDRATVEINSSGCYSTV 1724
Query: 5122 SVELKIHNLAVNALLKSNLVNXXXXXXXXXXXQDVNPRG-----INSNDNTS----FDET 5274
VEL I NLAVN +L+S+ VN DV + + N S +DET
Sbjct: 1725 CVELDIQNLAVNTILQSHHVNDMEGAGSMGISFDVIQQASLEDMVTGNQAASALANYDET 1784
Query: 5275 TGCAQAFRVLKQLIHSCLTDVRKSKNIYADSILQRLSWWLCSPSSKLHDPALHLMLHKVM 5454
C+ FR+LK ++ + ++ + NIYAD+ + WL SP S LHDPALH LH +M
Sbjct: 1785 ALCSSTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLQSPCSLLHDPALHRTLHNMM 1844
Query: 5455 QKVFALLLTDLRRLGAIIIYADFSKVIIDTVKFDLSAAKAYCESLLSTVRNRLVSSLLDI 5634
+K+F L+ + +RLG+ ++YA+F+++I+ T K + A AY E + +++ ++ + L I
Sbjct: 1845 KKLFLQLIAEFKRLGSSVVYANFNRIILCTKKRRIEDALAYVEYITNSIHSKEIFHSLTI 1904
Query: 5635 HVYDLKSHGLHSFS-CHDFCASPLTYNYAGIRADDEISLDEVTIEPKWSVARHLPEYIEV 5811
SFS C +F NY GI+ S+ ++ + S AR + E
Sbjct: 1905 -----------SFSRCWEFLLWMDPSNYGGIKGKVPSSIHCGQVKEQDSQAREETDEEEE 1953
Query: 5812 WRQNPHSNQC-------SFSENKKHVATHGP--------FFLDTDAFHLSWQRDXXXXXX 5946
++ + EN ++ P F + A+ ++ +
Sbjct: 1954 DKEKDEEEEGMGESEVEDLLENNWNILQFLPQAASCQSYFLMIVSAYIVAVYQSMKEELR 2013
Query: 5947 XXXXDPWKFAIENKKGSSESLEAQ--------MI----EYLREQIGSTFINMLVKKVDDI 6090
P ++ K S S E++ MI +Y+ ++ +F + K +
Sbjct: 2014 HSA--PGSTPVKRKGASQFSQESEGATGSLPGMITFSQDYVANELTQSFFTITQKIQKKV 2071
Query: 6091 MSHMKEINVSDASRV--SGQAPKGDYSLEFIQVISAVLALDQNVQQDVLLKTLFITDFIH 6264
S+ + + +LEFI+ + VL+LD N IT+ ++
Sbjct: 2072 TGSRNTTEPSEMFPILPGSHLLLNNPALEFIKYVCKVLSLDTN-----------ITNQVN 2120
Query: 6265 KSNLISGNVVLETMFTNRAGFFFEWVMRKSLLKYIKVKECAAEAEFLDPGPSFILPNVAC 6444
K N + LL+ + V E + EA+F DP S++LP V C
Sbjct: 2121 KLN-------------------------RDLLRLVDVGEFSEEAQFRDPCHSYVLPEVIC 2155
Query: 6445 SNCDAYRDLDICRDPALLTE----KEWSCADTQCGKIYDREQMESSLLEMVRQRERMYHM 6612
+C+ RDLD+C+D + + +W C++ C YD +ES+L+E ++++ + +
Sbjct: 2156 HSCNFCRDLDLCKDSSFSQDGAILPQWLCSN--CQAPYDSSAIESALVEALQRKLMAFTL 2213
Query: 6613 QDVVCIRCNQVKAAHLTEQCECSGSFRCKESGSEFSKRMEIFMDIAKRQKFRLLEEYISW 6792
QD+VC++C +K H+ C C+G F F +++ IF +IAK L+E I W
Sbjct: 2214 QDLVCLKCRGMKETHMPVYCSCAGDFTLTIRTEVFMEQIRIFQNIAKYYSMSYLQETIEW 2273
Query: 6793 II 6798
++
Sbjct: 2274 LL 2275
>gb|AAD45244.1|AF123502_1 DNA polymerase epsilon catalytic subunit [Mus musculus]
Length = 2284
Score = 1575 bits (4077), Expect = 0.0
Identities = 940/2345 (40%), Positives = 1332/2345 (56%), Gaps = 105/2345 (4%)
Frame = +1
Query: 79 DELESKLGFGLFSEGETRLGWLLTFSSSSWEDRDTGKVYSCVDLYFVTQDGFSFKTKYKF 258
D+++ + GF E R GWL+ + D D ++ S VD YF+ DG FK +
Sbjct: 42 DKMDLRFGFERLKEPGERTGWLINMHPTEILDEDK-RLVSAVDYYFIQDDGSRFKVALPY 100
Query: 259 RPYFYAATKDKMXXXXXXXXXXXXXXQVADIEIVEKEDLDLKNHLSGLQKKYLKISFDTV 438
PYFY A + ++A +E V KEDLDL NHL GL++ Y+K+SF TV
Sbjct: 101 MPYFYIAARKGCDREVSSFLSKKFQGKIAKLENVPKEDLDLPNHLVGLKRSYIKLSFHTV 160
Query: 439 QQLMEVKRDLLHIVERNQAKFDALEAYESILAG------------KREQRPQDCLDSIVD 582
+ L++V++++ V++N+ + A + Y ++L+ + ++ D LD+IVD
Sbjct: 161 EDLVKVRKEISPAVKKNREQDHASDEYTTMLSSILQGGSVITDEEETSKKIADQLDNIVD 220
Query: 583 LREYDVPYHVRFAIDNDVRSGQWYNVSI--SSTDVILEKRTDLLQRAEVRVCAFDIETTK 756
+REYDVPYH+R +ID + WYNV ++ V + +R DL++R + V AFDIETTK
Sbjct: 221 MREYDVPYHIRLSIDLRIHVAHWYNVRFRGNAFPVEITRRDDLVERPDPVVLAFDIETTK 280
Query: 757 LPLKFPDAEYDQIMMISYMVDGQGFLIINREVTACVGEDVEDLEYTPKPEFEGYFKVTNV 936
LPLKFPDAE DQIMMISYM+DGQG+LI NRE+ V ED+ED E+TPKPE+EG F V N
Sbjct: 281 LPLKFPDAETDQIMMISYMIDGQGYLITNREI---VSEDIEDFEFTPKPEYEGPFCVFNE 337
Query: 937 KNEVELLQRWFYHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNEELGFRCDQNQGE 1116
+EV L+QRWF H+QE KP I VTYNGDFFDWPF+E RA+ HG+ M +E+GF+ D +QGE
Sbjct: 338 PDEVHLIQRWFEHIQETKPTIMVTYNGDFFDWPFVEARAAIHGLSMYQEIGFQKD-SQGE 396
Query: 1117 CRAKFACHLDCFAWVKRDSYLPQGSHGLKAVTKAKLGYDPLEVNPEDMVRFAMEKPQTMA 1296
+A H+DC WVKRDSYLP GSH LKA KAKLGYDP+E++PEDM R A E+PQT+A
Sbjct: 397 YKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLA 456
Query: 1297 SYSVSDAVATYYLYMTYVNPFIFSLATIIPMVPDEVLRKGSGTLCEMLLMVEVSTYLPQA 1476
+YSVSDAVATYYLYM YV+PFIF+L TIIPM PDEVLRKGSGTLCE LLMV
Sbjct: 457 TYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMV--------- 507
Query: 1477 QAYKANVVCPNKNQADPEKFYQN-QLLESETYIGGHVECLESGQ---------------- 1605
QA+ AN++ PNK + + K + +L++ETY+GGHVE LESG
Sbjct: 508 QAFHANIIFPNKQEQEFNKLTDDGHVLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAF 567
Query: 1606 --LIDNLGRDLEYAITVEGKMRMDSISNYDEVKDEIKEKLEKLRDDPIREEGPLIYHLDV 1779
L+ + + + +AI E K+ ++ +N+ EV ++IK KL L+D P R E PLIYHLDV
Sbjct: 568 DFLLQRVEKTMRHAIEEEEKVPVEQATNFQEVCEQIKTKLTSLKDVPNRIECPLIYHLDV 627
Query: 1780 AAMYPNIILTNRLQVHLISPPSIVTDEICTACDFNRPGKTCLRKLEWVWRGVTFMGKKSD 1959
AMYPNIILTNRLQ P +IV + C ACDFN+PG +C RK+ W WRG +S+
Sbjct: 628 GAMYPNIILTNRLQ-----PSAIVDEATCAACDFNKPGASCQRKMAWQWRGEFMPASRSE 682
Query: 1960 YYHLKKQIESEFVDAGANIMSSKSFLDLPKVDQQSKLKERLKKYCQKAYKRVLDKPITEV 2139
Y+ ++ Q+ESE +++F +L + +Q K RL YC+KAYK++ + E
Sbjct: 683 YHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHVTKVEE- 741
Query: 2140 REAGICMRENPFYVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNSIKIQEAQDMVVVY 2319
R IC REN FYVDTVR+FRDRRYE+K L+KVWK KLS A G++ +++ ++M ++Y
Sbjct: 742 RLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDASEVKRCKNMEILY 801
Query: 2320 DSLQLAHKCILNSFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDT 2499
DSLQLAHKCILNSFYGYVMRKGARWYSMEMAG+V +TGA II AR LIE+IG+PLELDT
Sbjct: 802 DSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDT 861
Query: 2500 DGIWCCLPGSFPENFTFKTIDMK--KLTISYPCVMLNVDVAKNNTNDQYQTLVDPVRKTY 2673
DGIWC LP SFPENF KT + K KLTISYP MLN+ V + TN QYQ L +P TY
Sbjct: 862 DGIWCVLPNSFPENFVIKTTNAKKPKLTISYPGAMLNIMVKEGFTNHQYQELTEPSSLTY 921
Query: 2674 KSHSECSIEFEVDGPYKAMIIPASKEEGILIKKRYAVFNHDGTLAELKGFEIKRRGELKL 2853
+HSE SI FEVDGPY AMI+PASKEEG +KKRYAVFN DG+LAELKGFE+KRRGEL+L
Sbjct: 922 VTHSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQL 981
Query: 2854 IKVFQAELFDKFLHGSTLEECYSAVAAVADRWLDLLDVCEISCFFWVIYLIGFLSHFLQN 3033
IK+FQ+ +F+ FL GSTLEE Y +VA VAD WLD+ L +
Sbjct: 982 IKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDV----------------------LYS 1019
Query: 3034 QGKDIADSELLDYISESSTMSKSLADYGEQKSCAVTTAKRLAEFLGVTMVKDKGLRCQYI 3213
+ ++ DSEL + ISE+ +MS+ L DYGEQKS +++TAKRLAEFLG MVKD GL C+YI
Sbjct: 1020 KAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYI 1079
Query: 3214 VACEPKGTPVSERAVPVAIFTTNPEVMKFHLRKWCKTSS--DVGIRLIIDWSYYKQRLSS 3387
++ +P+G+PV+ERA+P+AIF P V K LRKW K+SS D IR I+DW YY +RL S
Sbjct: 1080 ISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGS 1139
Query: 3388 AIQKVITIPAAMQKVANPVPRVLHPDWLHKKVREKDDKFRQRKLVDMFSSANKDVVL--- 3558
AIQK+ITIPAA+Q+V NPVPRV HPDWLHKK+ EK+D ++Q+K+ ++F K ++
Sbjct: 1140 AIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDIYKQKKISELFVLEGKRQIVMAQ 1199
Query: 3559 --DTDLPVTKDNVEDIEDFCKENRPSVKGPKPIARSYEVNKKQSECEQQESWDTEFHDIS 3732
+ L + ++EDI K + +V R +E K+ + W
Sbjct: 1200 ASENSLSLCTPDMEDI-GLTKPHHSTVPVATKRKRVWETQKESQDIALTVPWQEVLGQPP 1258
Query: 3733 FQNIDKSVNYQGWLELKKRKWKVTLEKKKKRRLGDLRSSNQVDTHEINQKVGQGR----G 3900
+ + WL+ K+KW++ +++ LR ++++ E ++G R
Sbjct: 1259 SLGTTQE-EWLVWLQFHKKKWQLQAQQRLA-----LRKKQRLESAEDMPRLGPIREEPST 1312
Query: 3901 GVGSYFRRPEEALTSSHWQVCTIIQLVPSPQSGQFFAWVVVEGLMLKIPLSIPRVFYINS 4080
G+GS+ RR ++ WQ IIQ+ + Q+G F W ++ + I LSIPRVFY+N
Sbjct: 1313 GLGSFLRRTARSIMDLPWQ---IIQISETRQAGLFRLWAIIGNDLHCIKLSIPRVFYVNQ 1369
Query: 4081 KVPIDEYFQGKCVNKI----LPHGRPCYSLTEACVKIQEDQFKKESKKRAALLADPGVEG 4248
+V E G K+ Y+L E + ED +++ + L+ P +EG
Sbjct: 1370 RVAKAE--DGPAYRKVNRGLFLRSNIVYNLYE--YSVPEDMYQEHINEINTELSVPDIEG 1425
Query: 4249 IYETKVPLEFSAICQIGCVCKIDNKAKHRNTQDGWE-----VGELHMKTTTECHYLK-RS 4410
+YET+VPL F A+ Q+GCVC + NK R+ GWE + L M++ + YL+ S
Sbjct: 1426 VYETQVPLLFRALVQLGCVCVV-NKQLTRHL-SGWEAETFALEHLEMRSLAQFSYLEPGS 1483
Query: 4411 IPLVYLYNSTSTGRAIYVLYCHVSKLMSAVVVDPFNGNEL--LPSALERQFRXXXXXXXX 4584
I +YLY+ T +A++ ++ + S V+D N++ L + +
Sbjct: 1484 IRHIYLYHHTQGHKALFGVFIPSQRRASVFVLDTVRSNQMPGLSALYSSEHSLLLDKVDP 1543
Query: 4585 XXXXXXGIRFQVHYVDHPEAAKKIIQRAISEYREENCGPT-VAVIECPDFTFMKEGIKAL 4761
F+V + E + IQR + Y+EE GPT +AV + + I L
Sbjct: 1544 KLLPPPKHTFEVRAETNLETICRAIQRFLLAYKEERRGPTLIAVQSSWELCRLTSEIPVL 1603
Query: 4762 DDFPCVRIPFNDDDNSYQPVSWQRPAAKIAMFRCAAAFQWLDRRITQSRYAHVPLGNFGL 4941
++FP V I D SY + WQR A+ + L + SRY H+P+GN
Sbjct: 1604 EEFPLVPIRV-ADKISYAVLDWQRHGARRMIRHYLNLDLCLSQAFEMSRYFHIPVGNLPE 1662
Query: 4942 DWLTFTIDIFLSRALRDQQQVLWVSDNGVPDLGG---INNEEAFFADEVQQTSLVFPGAY 5112
D F D+F +R L+ +LW+S PDLGG +N D+ + G Y
Sbjct: 1663 DISIFGSDLFFARHLQHHNHLLWLSPTSRPDLGGKEADDNRLVMEFDDRATVEINSSGCY 1722
Query: 5113 RKVSVELKIHNLAVNALLKSNLVNXXXXXXXXXXXQDVNPRG-----INSNDNTS----F 5265
V VEL I NLAVN +L+S+ VN DV + + N S +
Sbjct: 1723 STVCVELDIQNLAVNTILQSHHVNDMEGAGSMGISFDVIQQASLEDMVTGNQAASALANY 1782
Query: 5266 DETTGCAQAFRVLKQLIHSCLTDVRKSKNIYADSILQRLSWWLCSPSSKLHDPALHLMLH 5445
DET C+ FR+LK ++ + ++ + NIYAD+ + WL SP S LHDPALH LH
Sbjct: 1783 DETALCSSTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLQSPCSLLHDPALHRTLH 1842
Query: 5446 KVMQKVFALLLTDLRRLGAIIIYADFSKVIIDTVKFDLSAAKAYCESLLSTVRNRLVSSL 5625
+M+K+F L+ + +RLG+ ++YA+F+++I+ T K + A AY E + +++ ++ +
Sbjct: 1843 NMMKKLFLQLIAEFKRLGSSVVYANFNRIILCTKKRRIEDALAYVEYITNSIHSKEIFHS 1902
Query: 5626 LDIHVYDLKSHGLHSFS-CHDFCASPLTYNYAGIRADDEISLDEVTIEPKWSVARHLPEY 5802
L I SFS C +F NY GI+ S+ ++ + S AR +
Sbjct: 1903 LTI-----------SFSRCWEFLLWMDPSNYGGIKGKVPSSIHCGQVKEQDSQAREETDE 1951
Query: 5803 IEVWRQNPHSNQC-------SFSENKKHVATHGP--------FFLDTDAFHLSWQRDXXX 5937
E ++ + EN ++ P F + A+ ++ +
Sbjct: 1952 EEEDKEKDEEEEGMGESEVEDLLENNWNILQFLPQAASCQSYFLMIVSAYIVAVYQSMKE 2011
Query: 5938 XXXXXXXDPWKFAIENKKGSSESLEAQ--------MI----EYLREQIGSTFINMLVKKV 6081
P ++ K S S E++ MI +Y+ ++ +F + K
Sbjct: 2012 ELRHSA--PGSTPVKRKGASQFSQESEGATGSLPGMITFSQDYVANELTQSFFTITQKIQ 2069
Query: 6082 DDIMSHMKEINVSDASRV--SGQAPKGDYSLEFIQVISAVLALDQNVQQDVLLKTLFITD 6255
+ S+ V + +LEFI+ + VL+ D N IT+
Sbjct: 2070 KKVTGSRNTTEPSEMFPVLPGSHLLLNNPALEFIKYVCKVLSQDTN-----------ITN 2118
Query: 6256 FIHKSNLISGNVVLETMFTNRAGFFFEWVMRKSLLKYIKVKECAAEAEFLDPGPSFILPN 6435
++K N + LL+ + V E + EA+F DP S++LP
Sbjct: 2119 QVNKLN-------------------------RDLLRLVDVGEFSEEAQFRDPCHSYVLPE 2153
Query: 6436 VACSNCDAYRDLDICRDPALLTE----KEWSCADTQCGKIYDREQMESSLLEMVRQRERM 6603
V C +C+ RDLD+C+D + + +W C++ C YD +ES+L+E ++++
Sbjct: 2154 VICHSCNFCRDLDLCKDSSFSQDGAILPQWLCSN--CQAPYDSSAIESALVEALQRKLMA 2211
Query: 6604 YHMQDVVCIRCNQVKAAHLTEQCECSGSFRCKESGSEFSKRMEIFMDIAKRQKFRLLEEY 6783
+ +QD+VC++C +K H+ C C+G F F +++ IF +IAK L+E
Sbjct: 2212 FTLQDLVCLKCRGMKETHMPVYCSCAGDFTLTIRTEVFMEQIRIFQNIAKYYSMSYLQET 2271
Query: 6784 ISWII 6798
I W++
Sbjct: 2272 IEWLL 2276
Database: BlastDB/NCBI/blast/db/2003_02_27_02_00_4/nr
Posted date: Feb 27, 2003 4:02 PM
Number of letters in database: 431,508,457
Number of sequences in database: 1,347,713
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
length of database: 431,508,457
effective HSP length: 139
effective length of database: 244,176,350
effective search space used: 520583978200
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)