BLASTX 1.4.13-Paracel [2002-12-12]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PTA.sd.7388.C1
(15,408 letters)
Database: BlastDB/NCBI/blast/db/2003_02_17_02_00_1/nr
1,339,046 sequences; 429,188,541 total letters
Searching...................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_186875.1| unknown protein; protein id: At3g02260.1 [... 9155 0.0
ref|NP_065816.1| retinoblastoma-associated factor 600 [Homo... 936 0.0
pir||T00076 hypothetical protein KIAA0462 - human (fragment... 936 0.0
ref|XP_233595.1| similar to retinoblastoma-associated facto... 897 0.0
gb|EAA01010.1| ebiP4133 [Anopheles gambiae str. PEST] 786 0.0
>ref|NP_186875.1| unknown protein; protein id: At3g02260.1 [Arabidopsis
thaliana]|gi|6041792|gb|AAF02112.1|AC009755_5 unknown
protein [Arabidopsis
thaliana]|gi|21779966|gb|AAM77595.1|AF507018_1 auxin
transport protein; BIG [Arabidopsis thaliana]
Length = 5079
Score = 9155 bits (23756), Expect = 0.0
Identities = 4665/5003 (93%), Positives = 4665/5003 (93%)
Frame = +1
Query: 1 MADDLANLCRFLFDDTAFPXXXXXXXXXXXXXXXXXXXXIKRGLRSFYLLLRWGVAPIGG 180
MADDLANLCRFLFDDTAFP IKRGLRSFYLLLRWGVAPIGG
Sbjct: 1 MADDLANLCRFLFDDTAFPSLSSSASSDLFSRRLRSDDSIKRGLRSFYLLLRWGVAPIGG 60
Query: 181 DDADSSGKLRFETWSDSQLQALVSISQAIXXXXXXXXXXXXXXNQGLVDQLEPIVLGVIQ 360
DDADSSGKLRFETWSDSQLQALVSISQAI NQGLVDQLEPIVLGVIQ
Sbjct: 61 DDADSSGKLRFETWSDSQLQALVSISQAILLLSRSLLGTDLTLNQGLVDQLEPIVLGVIQ 120
Query: 361 EVMXXXXXXXXXXXXRQNDLKMEINMEILLEIASFDGSEKQYDILPDFSPAEVAELWPAF 540
EVM RQNDLKMEINMEILLEIASFDGSEKQYDILPDFSPAEVAELWPAF
Sbjct: 121 EVMEFSLSFLEKSSFRQNDLKMEINMEILLEIASFDGSEKQYDILPDFSPAEVAELWPAF 180
Query: 541 SGEHDNMDAQSLVKCTFQGGRCSNEEKPVDRLLITLMSECIESDVQAQSVVKSPFQQDCG 720
SGEHDNMDAQSLVKCTFQGGRCSNEEKPVDRLLITLMSECIESDVQAQSVVKSPFQQDCG
Sbjct: 181 SGEHDNMDAQSLVKCTFQGGRCSNEEKPVDRLLITLMSECIESDVQAQSVVKSPFQQDCG 240
Query: 721 DLNPFTRHLAVVHLRCVCRLIMVCKELVQLPNMLDEKTVDQAVLDKLSFCLRILKLLGSL 900
DLNPFTRHLAVVHLRCVCRLIMVCKELVQLPNMLDEKTVDQAVLDKLSFCLRILKLLGSL
Sbjct: 241 DLNPFTRHLAVVHLRCVCRLIMVCKELVQLPNMLDEKTVDQAVLDKLSFCLRILKLLGSL 300
Query: 901 SKDVQSIENDGSLLQAVASFTDAFPKLFRVFFEFTNHTATEGNIESLSLALVEGFLNLVQ 1080
SKDVQSIENDGSLLQAVASFTDAFPKLFRVFFEFTNHTATEGNIESLSLALVEGFLNLVQ
Sbjct: 301 SKDVQSIENDGSLLQAVASFTDAFPKLFRVFFEFTNHTATEGNIESLSLALVEGFLNLVQ 360
Query: 1081 LIFGKSSVFQNVQACVAASIVSNLDSSVWRYDGSSCNLTPPLAYFPRSVIYTLKLIQDLK 1260
LIFGKSSVFQNVQACVAASIVSNLDSSVWRYDGSSCNLTPPLAYFPRSVIYTLKLIQDLK
Sbjct: 361 LIFGKSSVFQNVQACVAASIVSNLDSSVWRYDGSSCNLTPPLAYFPRSVIYTLKLIQDLK 420
Query: 1261 RQPYHIHDLRVLESEVTYEDVSSTVDSVYFHLRQEKIPLLKCFTVEDIMRVIFPSSSQWM 1440
RQPYHIHDLRVLESEVTYEDVSSTVDSVYFHLRQEKIPLLKCFTVEDIMRVIFPSSSQWM
Sbjct: 421 RQPYHIHDLRVLESEVTYEDVSSTVDSVYFHLRQEKIPLLKCFTVEDIMRVIFPSSSQWM 480
Query: 1441 DNFFHLVYFLHREGVKLRPKVERTYSSLRSNSFAEVESQISHDDEALFGNLFSEGSRSLC 1620
DNFFHLVYFLHREGVKLRPKVERTYSSLRSNSFAEVESQISHDDEALFGNLFSEGSRSLC
Sbjct: 481 DNFFHLVYFLHREGVKLRPKVERTYSSLRSNSFAEVESQISHDDEALFGNLFSEGSRSLC 540
Query: 1621 SIEPNDQPPVSVSSNLLLQAAKELLNFLRACILCQEWVPSIYEDGCKKLDTGHIDILLNI 1800
SIEPNDQPPVSVSSNLLLQAAKELLNFLRACILCQEWVPSIYEDGCKKLDTGHIDILLNI
Sbjct: 541 SIEPNDQPPVSVSSNLLLQAAKELLNFLRACILCQEWVPSIYEDGCKKLDTGHIDILLNI 600
Query: 1801 VGCSIEDKASDGGCMLQDEGRPGHVAFEXXXXXXXXXXXXDFLESYLFQQILVVENSDFN 1980
VGCSIEDKASDGGCMLQDEGRPGHVAFE DFLESYLFQQILVVENSDFN
Sbjct: 601 VGCSIEDKASDGGCMLQDEGRPGHVAFELLLNLLRSRALSDFLESYLFQQILVVENSDFN 660
Query: 1981 YNDKTLALLAHTLLCRPGLAGAQLRAKIYDGFVSFVTERARGICAEALSLKELTACLPSA 2160
YNDKTLALLAHTLLCRPGLAGAQLRAKIYDGFVSFVTERARGICAEALSLKELTACLPSA
Sbjct: 661 YNDKTLALLAHTLLCRPGLAGAQLRAKIYDGFVSFVTERARGICAEALSLKELTACLPSA 720
Query: 2161 FHIEILLMAFHLSNEAEKAKFSNLIASCLHKVDTPAGICDGPQLSSWAMLISRXXXXXXX 2340
FHIEILLMAFHLSNEAEKAKFSNLIASCLHKVDTPAGICDGPQLSSWAMLISR
Sbjct: 721 FHIEILLMAFHLSNEAEKAKFSNLIASCLHKVDTPAGICDGPQLSSWAMLISRLLVLLHH 780
Query: 2341 XXXXPNTCPTSLMLDLRSKLREVRSCGSNLHVTVGDHLSSWASLVARGITDSWAEDESVS 2520
PNTCPTSLMLDLRSKLREVRSCGSNLHVTVGDHLSSWASLVARGITDSWAEDESVS
Sbjct: 781 MLLHPNTCPTSLMLDLRSKLREVRSCGSNLHVTVGDHLSSWASLVARGITDSWAEDESVS 840
Query: 2521 HLMSQMIDFSPHPPTFQNDVSTAKTLNLDYGDLSASLCRVLGLWKGKKAGKVEDLLVERY 2700
HLMSQMIDFSPHPPTFQNDVSTAKTLNLDYGDLSASLCRVLGLWKGKKAGKVEDLLVERY
Sbjct: 841 HLMSQMIDFSPHPPTFQNDVSTAKTLNLDYGDLSASLCRVLGLWKGKKAGKVEDLLVERY 900
Query: 2701 IFMLSSDIARINCALDSQPSLHVNYQNVDISNSVDLISTSHLLVGDINVVGRNIELRNIL 2880
IFMLSSDIARINCALDSQPSLHVNYQNVDISNSVDLISTSHLLVGDINVVGRNIELRNIL
Sbjct: 901 IFMLSSDIARINCALDSQPSLHVNYQNVDISNSVDLISTSHLLVGDINVVGRNIELRNIL 960
Query: 2881 IGVLNQLQAAPEQVVEDLGWDYIREGAWLSLLLYFLDGGVWDYCNKNSCSEIDPFWKECT 3060
IGVLNQLQAAPEQVVEDLGWDYIREGAWLSLLLYFLDGGVWDYCNKNSCSEIDPFWKECT
Sbjct: 961 IGVLNQLQAAPEQVVEDLGWDYIREGAWLSLLLYFLDGGVWDYCNKNSCSEIDPFWKECT 1020
Query: 3061 SVDAKYVAAAEGVVSYLMKTGDIAELLRMLSSLVGKYLRVYKKAFLATFSDWNXXXXXXX 3240
SVDAKYVAAAEGVVSYLMKTGDIAELLRMLSSLVGKYLRVYKKAFLATFSDWN
Sbjct: 1021 SVDAKYVAAAEGVVSYLMKTGDIAELLRMLSSLVGKYLRVYKKAFLATFSDWNHHGHSSP 1080
Query: 3241 XXXXXXXTQFGKSLQGEYAKIGDNSLHLQCIFYLSKLDSLGDGRGSGVLWKVFWEFMVHG 3420
TQFGKSLQGEYAKIGDNSLHLQCIFYLSKLDSLGDGRGSGVLWKVFWEFMVHG
Sbjct: 1081 SLLLLKHTQFGKSLQGEYAKIGDNSLHLQCIFYLSKLDSLGDGRGSGVLWKVFWEFMVHG 1140
Query: 3421 FPTSLQTXXXXXXXXXXXXXXXXXTINGLLKLGNSKEKFGVDTSVLHQLLDSIMIIKFDQ 3600
FPTSLQT TINGLLKLGNSKEKFGVDTSVLHQLLDSIMIIKFDQ
Sbjct: 1141 FPTSLQTSSAILLSCILSIRCIVLTINGLLKLGNSKEKFGVDTSVLHQLLDSIMIIKFDQ 1200
Query: 3601 VFESFHGKCEEIHQNICAVLQLPDLTELFLMKDMEGFVRDISAEQIDRSQVLEGVITKIV 3780
VFESFHGKCEEIHQNICAVLQLPDLTELFLMKDMEGFVRDISAEQIDRSQVLEGVITKIV
Sbjct: 1201 VFESFHGKCEEIHQNICAVLQLPDLTELFLMKDMEGFVRDISAEQIDRSQVLEGVITKIV 1260
Query: 3781 DVMXXXXXXXXXXXIFKFYLGVDAVSEHTREFYELQRGDLSVFIDSLDYCSLEPVNIKVL 3960
DVM IFKFYLGVDAVSEHTREFYELQRGDLSVFIDSLDYCSLEPVNIKVL
Sbjct: 1261 DVMDSLSKDSSKSDIFKFYLGVDAVSEHTREFYELQRGDLSVFIDSLDYCSLEPVNIKVL 1320
Query: 3961 NFLVDLLSVAQSPDLRRRVQQKFIDMDLISLSGWLERRLLGSFVEEIDGKKTAKGNSLPF 4140
NFLVDLLSVAQSPDLRRRVQQKFIDMDLISLSGWLERRLLGSFVEEIDGKKTAKGNSLPF
Sbjct: 1321 NFLVDLLSVAQSPDLRRRVQQKFIDMDLISLSGWLERRLLGSFVEEIDGKKTAKGNSLPF 1380
Query: 4141 REAAMNFINCLVSSTNDLQTRELQNHLFEALLISLDTAFLSFDIHMSMSYFHFVLQLARE 4320
REAAMNFINCLVSSTNDLQTRELQNHLFEALLISLDTAFLSFDIHMSMSYFHFVLQLARE
Sbjct: 1381 REAAMNFINCLVSSTNDLQTRELQNHLFEALLISLDTAFLSFDIHMSMSYFHFVLQLARE 1440
Query: 4321 DNLMKMVLKRTIXXXXXXXXXXXXXPGLKFIFGVIGTLLSNRSPSHGESLCGKSLASYKN 4500
DNLMKMVLKRTI PGLKFIFGVIGTLLSNRSPSHGESLCGKSLASYKN
Sbjct: 1441 DNLMKMVLKRTIMLMEKLAAEEKLLPGLKFIFGVIGTLLSNRSPSHGESLCGKSLASYKN 1500
Query: 4501 TATGPLVPKLSGTTKKSDTLALPVDQEGSSISLECXXXXXXXXXXXXXXXXXXASLDKED 4680
TATGPLVPKLSGTTKKSDTLALPVDQEGSSISLEC ASLDKED
Sbjct: 1501 TATGPLVPKLSGTTKKSDTLALPVDQEGSSISLECDVTSVDEDEDDGTSDGEVASLDKED 1560
Query: 4681 EEDANSERYLASKVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHRGHRVVYS 4860
EEDANSERYLASKVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHRGHRVVYS
Sbjct: 1561 EEDANSERYLASKVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHRGHRVVYS 1620
Query: 4861 RSSRFFCDCGAGGVRGSSCQCLKPRKYNGNGSAPARGTNNFQSFLPLSEDADQLGESDSD 5040
RSSRFFCDCGAGGVRGSSCQCLKPRKYNGNGSAPARGTNNFQSFLPLSEDADQLGESDSD
Sbjct: 1621 RSSRFFCDCGAGGVRGSSCQCLKPRKYNGNGSAPARGTNNFQSFLPLSEDADQLGESDSD 1680
Query: 5041 VEEDGFGEENHVVLYIPKETQYKMSLLLEELGIEDRVLELFSSLLPSITSKRDSGLSKEK 5220
VEEDGFGEENHVVLYIPKETQYKMSLLLEELGIEDRVLELFSSLLPSITSKRDSGLSKEK
Sbjct: 1681 VEEDGFGEENHVVLYIPKETQYKMSLLLEELGIEDRVLELFSSLLPSITSKRDSGLSKEK 1740
Query: 5221 QVNLGKDKVLSFDTDLLQLKKAYKSGSLDLKIKADYTNSKDLKSLLANXXXXXXXXXXXX 5400
QVNLGKDKVLSFDTDLLQLKKAYKSGSLDLKIKADYTNSKDLKSLLAN
Sbjct: 1741 QVNLGKDKVLSFDTDLLQLKKAYKSGSLDLKIKADYTNSKDLKSLLANGSLVKSLLSVSV 1800
Query: 5401 XXXXXXGEGDKVAIFDVGQLIGQATIAPINADKANVKPLSRNIVRFEIVHLSFNPVVENY 5580
GEGDKVAIFDVGQLIGQATIAPINADKANVKPLSRNIVRFEIVHLSFNPVVENY
Sbjct: 1801 RGRLAVGEGDKVAIFDVGQLIGQATIAPINADKANVKPLSRNIVRFEIVHLSFNPVVENY 1860
Query: 5581 LAVAGLEDCQILTLNHRGEVIDRLAVELALQGAFIRRIDWVPGSQVQLMVVTNKFVKIYD 5760
LAVAGLEDCQILTLNHRGEVIDRLAVELALQGAFIRRIDWVPGSQVQLMVVTNKFVKIYD
Sbjct: 1861 LAVAGLEDCQILTLNHRGEVIDRLAVELALQGAFIRRIDWVPGSQVQLMVVTNKFVKIYD 1920
Query: 5761 LSQDSISPTQYFTLPNDMIVDATLFVASRGRVFLLVLSEQGNLYRFELSWGGNAGATPLK 5940
LSQDSISPTQYFTLPNDMIVDATLFVASRGRVFLLVLSEQGNLYRFELSWGGNAGATPLK
Sbjct: 1921 LSQDSISPTQYFTLPNDMIVDATLFVASRGRVFLLVLSEQGNLYRFELSWGGNAGATPLK 1980
Query: 5941 EIVQIMGKDVTGKGSSVYFSPTYRLLFISYHDGSSFMGRXXXXXXXXXXXXGMFEEESDC 6120
EIVQIMGKDVTGKGSSVYFSPTYRLLFISYHDGSSFMGR GMFEEESDC
Sbjct: 1981 EIVQIMGKDVTGKGSSVYFSPTYRLLFISYHDGSSFMGRLSSDATSLTDTSGMFEEESDC 2040
Query: 6121 KQRVAGLHRWKELLAGSGLFICFSSVKSNAVLAVSLRGDGVCAQNLRHPTGSSSPMVGIT 6300
KQRVAGLHRWKELLAGSGLFICFSSVKSNAVLAVSLRGDGVCAQNLRHPTGSSSPMVGIT
Sbjct: 2041 KQRVAGLHRWKELLAGSGLFICFSSVKSNAVLAVSLRGDGVCAQNLRHPTGSSSPMVGIT 2100
Query: 6301 AYKPLSKDNVHCLVLHDDGSLQIYSHVRSGVDTDSNFTAEKVKKLGSKILNNKTYAGAKP 6480
AYKPLSKDNVHCLVLHDDGSLQIYSHVRSGVDTDSNFTAEKVKKLGSKILNNKTYAGAKP
Sbjct: 2101 AYKPLSKDNVHCLVLHDDGSLQIYSHVRSGVDTDSNFTAEKVKKLGSKILNNKTYAGAKP 2160
Query: 6481 EFPLDFFERAFCITADVRLGSDAIRNGDSEGAKQSLASEDGFIESPSPVGFKISVSNPNP 6660
EFPLDFFERAFCITADVRLGSDAIRNGDSEGAKQSLASEDGFIESPSPVGFKISVSNPNP
Sbjct: 2161 EFPLDFFERAFCITADVRLGSDAIRNGDSEGAKQSLASEDGFIESPSPVGFKISVSNPNP 2220
Query: 6661 DIVMVGIRMHVGTTSASSIPSEVTIFQRSIKMDEGMRCWYDIPFTVAESLLADEDVVISV 6840
DIVMVGIRMHVGTTSASSIPSEVTIFQRSIKMDEGMRCWYDIPFTVAESLLADEDVVISV
Sbjct: 2221 DIVMVGIRMHVGTTSASSIPSEVTIFQRSIKMDEGMRCWYDIPFTVAESLLADEDVVISV 2280
Query: 6841 GPTTSGTALPRIDSLEVYGRAKDEFGWKEKMDAVLDMEARVLGHGLLLPGSSKKRALAQS 7020
GPTTSGTALPRIDSLEVYGRAKDEFGWKEKMDAVLDMEARVLGHGLLLPGSSKKRALAQS
Sbjct: 2281 GPTTSGTALPRIDSLEVYGRAKDEFGWKEKMDAVLDMEARVLGHGLLLPGSSKKRALAQS 2340
Query: 7021 ASMEEQVIADGLKLLSIYYSVCRPRQEVVLSELKCKQLLETIFESDRETLLQTTACRVLQ 7200
ASMEEQVIADGLKLLSIYYSVCRPRQEVVLSELKCKQLLETIFESDRETLLQTTACRVLQ
Sbjct: 2341 ASMEEQVIADGLKLLSIYYSVCRPRQEVVLSELKCKQLLETIFESDRETLLQTTACRVLQ 2400
Query: 7201 SVFPRKEIYYQVMFLPNSVKDTMRLLGVVKVTSILSSRLGILGTGGSIVEEFNAQMRAVS 7380
SVFPRKEIYYQVMFLPNSVKDTMRLLGVVKVTSILSSRLGILGTGGSIVEEFNAQMRAVS
Sbjct: 2401 SVFPRKEIYYQVMFLPNSVKDTMRLLGVVKVTSILSSRLGILGTGGSIVEEFNAQMRAVS 2460
Query: 7381 KVALTRKSNFSVFLEMNGSEVVDNLMQVLWGILESEPLDTPTMNNVVMSSVELIYSYAEC 7560
KVALTRKSNFSVFLEMNGSEVVDNLMQVLWGILESEPLDTPTMNNVVMSSVELIYSYAEC
Sbjct: 2461 KVALTRKSNFSVFLEMNGSEVVDNLMQVLWGILESEPLDTPTMNNVVMSSVELIYSYAEC 2520
Query: 7561 LASQGKDTGVHSVAPAVQLLKALMLFPNESVQTSSRCVLVLAISSRLLQVPFPKQXXXXX 7740
LASQGKDTGVHSVAPAVQLLKALMLFPNESVQTSSRCVLVLAISSRLLQVPFPKQ
Sbjct: 2521 LASQGKDTGVHSVAPAVQLLKALMLFPNESVQTSSRCVLVLAISSRLLQVPFPKQTMLTT 2580
Query: 7741 XXXXXXXXXPSVPIRTAGGNTHVMIEEDSITSSVQYCCDGCSTVPILRRRWHCTVCPDFD 7920
PSVPIRTAGGNTHVMIEEDSITSSVQYCCDGCSTVPILRRRWHCTVCPDFD
Sbjct: 2581 DDLVDNVTTPSVPIRTAGGNTHVMIEEDSITSSVQYCCDGCSTVPILRRRWHCTVCPDFD 2640
Query: 7921 LCEACYEVLDADRLPPPHTRDHPMTAIPIEVESLGADTNEIQFSADEVGISNMLPVVTSS 8100
LCEACYEVLDADRLPPPHTRDHPMTAIPIEVESLGADTNEIQFSADEVGISNMLPVVTSS
Sbjct: 2641 LCEACYEVLDADRLPPPHTRDHPMTAIPIEVESLGADTNEIQFSADEVGISNMLPVVTSS 2700
Query: 8101 IPQASTPSIHVLEPGESAEFSASLTDPISISASKRAVNSLILSEFLQELSGWMETVSGVQ 8280
IPQASTPSIHVLEPGESAEFSASLTDPISISASKRAVNSLILSEFLQELSGWMETVSGVQ
Sbjct: 2701 IPQASTPSIHVLEPGESAEFSASLTDPISISASKRAVNSLILSEFLQELSGWMETVSGVQ 2760
Query: 8281 AIPVMQLFYRLSSAIGGAFMDSSKPEEISLDKLIKWLLGEINLSKPFAASTRSSLGEIVI 8460
AIPVMQLFYRLSSAIGGAFMDSSKPEEISLDKLIKWLLGEINLSKPFAASTRSSLGEIVI
Sbjct: 2761 AIPVMQLFYRLSSAIGGAFMDSSKPEEISLDKLIKWLLGEINLSKPFAASTRSSLGEIVI 2820
Query: 8461 LVFMFFTLMLRSWHQPXXXXXXXXXXXXTDVHDRRIXXXXXXXXXXXXLHVQERDDFASQ 8640
LVFMFFTLMLRSWHQP TDVHDRRI LHVQERDDFASQ
Sbjct: 2821 LVFMFFTLMLRSWHQPGSDGSSSKLGGSTDVHDRRIVQSSTVVATQSSLHVQERDDFASQ 2880
Query: 8641 LVRACSCLRNQEFVNYLMNILQQLVHVFKSRAANVEARXXXXXXXXXAMLTVRRDLPAGN 8820
LVRACSCLRNQEFVNYLMNILQQLVHVFKSRAANVEAR AMLTVRRDLPAGN
Sbjct: 2881 LVRACSCLRNQEFVNYLMNILQQLVHVFKSRAANVEARGSSSGSGCGAMLTVRRDLPAGN 2940
Query: 8821 YSPFFSDSYAKAHRADIFVDYHRLLLENVFRLVYTLVRPEKQEKMGEKEKVYRNASSKDL 9000
YSPFFSDSYAKAHRADIFVDYHRLLLENVFRLVYTLVRPEKQEKMGEKEKVYRNASSKDL
Sbjct: 2941 YSPFFSDSYAKAHRADIFVDYHRLLLENVFRLVYTLVRPEKQEKMGEKEKVYRNASSKDL 3000
Query: 9001 KLDGFQDVLCSYINNPHTAFVRRYARRLFLHLCGSKTQYYSVRDSWQFSNEVKNLYKHVE 9180
KLDGFQDVLCSYINNPHTAFVRRYARRLFLHLCGSKTQYYSVRDSWQFSNEVKNLYKHVE
Sbjct: 3001 KLDGFQDVLCSYINNPHTAFVRRYARRLFLHLCGSKTQYYSVRDSWQFSNEVKNLYKHVE 3060
Query: 9181 KSGGFENNVSYERSVKIVKSLSTIAEVAVARPRNWQKYCLRHGDFLSFLLNGVFHFAEES 9360
KSGGFENNVSYERSVKIVKSLSTIAEVAVARPRNWQKYCLRHGDFLSFLLNGVFHFAEES
Sbjct: 3061 KSGGFENNVSYERSVKIVKSLSTIAEVAVARPRNWQKYCLRHGDFLSFLLNGVFHFAEES 3120
Query: 9361 VIQTLKLLNLAFYQGKDVSSSVQKAEATEVVTGSNRSGSQSVDSKKKKKGEDGHDSGLEK 9540
VIQTLKLLNLAFYQGKDVSSSVQKAEATEVVTGSNRSGSQSVDSKKKKKGEDGHDSGLEK
Sbjct: 3121 VIQTLKLLNLAFYQGKDVSSSVQKAEATEVVTGSNRSGSQSVDSKKKKKGEDGHDSGLEK 3180
Query: 9541 LYVDMEGVVDIFSANCGDLLRQFIDFFLLEWNSSSVRTEAKSVIYGLWHHGRHSFKESLL 9720
LYVDMEGVVDIFSANCGDLLRQFIDFFLLEWNSSSVRTEAKSVIYGLWHHGRHSFKESLL
Sbjct: 3181 LYVDMEGVVDIFSANCGDLLRQFIDFFLLEWNSSSVRTEAKSVIYGLWHHGRHSFKESLL 3240
Query: 9721 AALLQKVRYLPAYGQNIVEYTELVSLLLDKAPENNSKQAINELVDRCLNPDVIRCFFETL 9900
AALLQKVRYLPAYGQNIVEYTELVSLLLDKAPENNSKQAINELVDRCLNPDVIRCFFETL
Sbjct: 3241 AALLQKVRYLPAYGQNIVEYTELVSLLLDKAPENNSKQAINELVDRCLNPDVIRCFFETL 3300
Query: 9901 HSQNELIANHPNSRIYSTLGNLVEFDGYYLESEPCVACSSPDVPYSKMKLESLKSETKFT 10080
HSQNELIANHPNSRIYSTLGNLVEFDGYYLESEPCVACSSPDVPYSKMKLESLKSETKFT
Sbjct: 3301 HSQNELIANHPNSRIYSTLGNLVEFDGYYLESEPCVACSSPDVPYSKMKLESLKSETKFT 3360
Query: 10081 DNRIIVKCTGSYTIQSVTMNVHDARKSKSVKVLNLYYNNRPVSDLSELKNNWSLWKRAKS 10260
DNRIIVKCTGSYTIQSVTMNVHDARKSKSVKVLNLYYNNRPVSDLSELKNNWSLWKRAKS
Sbjct: 3361 DNRIIVKCTGSYTIQSVTMNVHDARKSKSVKVLNLYYNNRPVSDLSELKNNWSLWKRAKS 3420
Query: 10261 CHLSFNQTELKVEFPIPITACNFMIELDSFYENLQALSLEPLQCPRCSRPVTDKHGICSN 10440
CHLSFNQTELKVEFPIPITACNFMIELDSFYENLQALSLEPLQCPRCSRPVTDKHGICSN
Sbjct: 3421 CHLSFNQTELKVEFPIPITACNFMIELDSFYENLQALSLEPLQCPRCSRPVTDKHGICSN 3480
Query: 10441 CHENAYQCRQCRNINYENLDSFLCNECGYSKYGRFEFNFMAKPSFIFDNMENDEDMKKGL 10620
CHENAYQCRQCRNINYENLDSFLCNECGYSKYGRFEFNFMAKPSFIFDNMENDEDMKKGL
Sbjct: 3481 CHENAYQCRQCRNINYENLDSFLCNECGYSKYGRFEFNFMAKPSFIFDNMENDEDMKKGL 3540
Query: 10621 AAIESESENAHKRYQQLLGFKKPLLKIVSSIGETEMDSQHKDTVQQMMASLPGPSCKINR 10800
AAIESESENAHKRYQQLLGFKKPLLKIVSSIGETEMDSQHKDTVQQMMASLPGPSCKINR
Sbjct: 3541 AAIESESENAHKRYQQLLGFKKPLLKIVSSIGETEMDSQHKDTVQQMMASLPGPSCKINR 3600
Query: 10801 KIALLGVLYGEKCKAAFDSVSKSVQTLQGLRRVLMSYLHQKNSNFSSGASRCVVSKTPNN 10980
KIALLGVLYGEKCKAAFDSVSKSVQTLQGLRRVLMSYLHQKNSNFSSGASRCVVSKTPNN
Sbjct: 3601 KIALLGVLYGEKCKAAFDSVSKSVQTLQGLRRVLMSYLHQKNSNFSSGASRCVVSKTPNN 3660
Query: 10981 CYGCATTFVTQCLEILQVLSKHPRSRKQLVAAGILSELFENNIHQGPKTARAQARAALST 11160
CYGCATTFVTQCLEILQVLSKHPRSRKQLVAAGILSELFENNIHQGPKTARAQARAALST
Sbjct: 3661 CYGCATTFVTQCLEILQVLSKHPRSRKQLVAAGILSELFENNIHQGPKTARAQARAALST 3720
Query: 11161 FSEGDLSAVNELNNLVQKKIMYCLEHHRSMDIALATREEMLLLSEVCSLTDEFWESRLRL 11340
FSEGDLSAVNELNNLVQKKIMYCLEHHRSMDIALATREEMLLLSEVCSLTDEFWESRLRL
Sbjct: 3721 FSEGDLSAVNELNNLVQKKIMYCLEHHRSMDIALATREEMLLLSEVCSLTDEFWESRLRL 3780
Query: 11341 VFQLLFSSIKLGAKHPAISEHIILPCLKIISVACTPPKPDTAEKEQTMGKSAPAVQEKDE 11520
VFQLLFSSIKLGAKHPAISEHIILPCLKIISVACTPPKPDTAEKEQTMGKSAPAVQEKDE
Sbjct: 3781 VFQLLFSSIKLGAKHPAISEHIILPCLKIISVACTPPKPDTAEKEQTMGKSAPAVQEKDE 3840
Query: 11521 NAAGVIKYXXXXXXXXXXVSQKTRDIQLVSYLEWEKGASYLDFVRRQYKASQSIRGASQK 11700
NAAGVIKY VSQKTRDIQLVSYLEWEKGASYLDFVRRQYKASQSIRGASQK
Sbjct: 3841 NAAGVIKYSSESEENNLNVSQKTRDIQLVSYLEWEKGASYLDFVRRQYKASQSIRGASQK 3900
Query: 11701 SRTHRSDFLALKYTLRWKRRSSRTSKGGLQAFELGSWVTELILSACSQSIRSEMCTLISL 11880
SRTHRSDFLALKYTLRWKRRSSRTSKGGLQAFELGSWVTELILSACSQSIRSEMCTLISL
Sbjct: 3901 SRTHRSDFLALKYTLRWKRRSSRTSKGGLQAFELGSWVTELILSACSQSIRSEMCTLISL 3960
Query: 11881 LAAQSSPRRYRLINLLIGLLPATLAAGESSAEYFELLFKMIETQDALLFLTVRGCLTTIC 12060
LAAQSSPRRYRLINLLIGLLPATLAAGESSAEYFELLFKMIETQDALLFLTVRGCLTTIC
Sbjct: 3961 LAAQSSPRRYRLINLLIGLLPATLAAGESSAEYFELLFKMIETQDALLFLTVRGCLTTIC 4020
Query: 12061 KLISQEVGNIESLERSLQIDISQXXXXXXXXXXXXXXXXVPNIRSRFMRDNLLSHVLEAL 12240
KLISQEVGNIESLERSLQIDISQ VPNIRSRFMRDNLLSHVLEAL
Sbjct: 4021 KLISQEVGNIESLERSLQIDISQGFTLHKLLELLGKFLEVPNIRSRFMRDNLLSHVLEAL 4080
Query: 12241 IVIRGLIVQKTKLINDCNRRXXXXXXXXXXESSENKRQFIRACVSGLQTHAEENKGRTCL 12420
IVIRGLIVQKTKLINDCNRR ESSENKRQFIRACVSGLQTHAEENKGRTCL
Sbjct: 4081 IVIRGLIVQKTKLINDCNRRLKDLLDGLLLESSENKRQFIRACVSGLQTHAEENKGRTCL 4140
Query: 12421 FILEQLCNLICPSKPEAVYMLILNKSHTQEEFIRGSMTKNPYSSAEIGPLMRDVKNKICQ 12600
FILEQLCNLICPSKPEAVYMLILNKSHTQEEFIRGSMTKNPYSSAEIGPLMRDVKNKICQ
Sbjct: 4141 FILEQLCNLICPSKPEAVYMLILNKSHTQEEFIRGSMTKNPYSSAEIGPLMRDVKNKICQ 4200
Query: 12601 QXXXXXXXXXXXXXXXXVAGNIISLDLSIAQVYELVWKKSNQDCPPMTVTYRLQGLDGEA 12780
Q VAGNIISLDLSIAQVYELVWKKSNQDCPPMTVTYRLQGLDGEA
Sbjct: 4201 QLDLLGLLEDDYGMELLVAGNIISLDLSIAQVYELVWKKSNQDCPPMTVTYRLQGLDGEA 4260
Query: 12781 TEPMIKELEEDREESQDPEIEFAIAGAVREYGGLEILLDMIKSLQDDFKSNQEEMVAVLD 12960
TEPMIKELEEDREESQDPEIEFAIAGAVREYGGLEILLDMIKSLQDDFKSNQEEMVAVLD
Sbjct: 4261 TEPMIKELEEDREESQDPEIEFAIAGAVREYGGLEILLDMIKSLQDDFKSNQEEMVAVLD 4320
Query: 12961 LLNHCCKIRENXXXXXXXXXXXXXXXXXXRAFSVDAMEPAEGILLIVESLTLEANESDSI 13140
LLNHCCKIREN RAFSVDAMEPAEGILLIVESLTLEANESDSI
Sbjct: 4321 LLNHCCKIRENRRALLRLGALSLLLETARRAFSVDAMEPAEGILLIVESLTLEANESDSI 4380
Query: 13141 SAAQSALTVSNEETGTWEQAKKIVLMFLERLSHPSGLKKSNKQQRNTEMVARILPYLTYG 13320
SAAQSALTVSNEETGTWEQAKKIVLMFLERLSHPSGLKKSNKQQRNTEMVARILPYLTYG
Sbjct: 4381 SAAQSALTVSNEETGTWEQAKKIVLMFLERLSHPSGLKKSNKQQRNTEMVARILPYLTYG 4440
Query: 13321 EPAAMEALIEHFSPYLQNWSEFDQLQQRHEEDPKDDSIAQQAAKQRFTVENFVRVSESLK 13500
EPAAMEALIEHFSPYLQNWSEFDQLQQRHEEDPKDDSIAQQAAKQRFTVENFVRVSESLK
Sbjct: 4441 EPAAMEALIEHFSPYLQNWSEFDQLQQRHEEDPKDDSIAQQAAKQRFTVENFVRVSESLK 4500
Query: 13501 TSSCGERLKDIVLENGIIAVAVKHIKEIFAITGQTGFKSSKEWLLALKLPSVPLILSMLR 13680
TSSCGERLKDIVLENGIIAVAVKHIKEIFAITGQTGFKSSKEWLLALKLPSVPLILSMLR
Sbjct: 4501 TSSCGERLKDIVLENGIIAVAVKHIKEIFAITGQTGFKSSKEWLLALKLPSVPLILSMLR 4560
Query: 13681 GLSMGHLPTQTCIDEGGILTLLHALEGVSGENDIGARAENLLDTLADKEGKGDGFLGEKV 13860
GLSMGHLPTQTCIDEGGILTLLHALEGVSGENDIGARAENLLDTLADKEGKGDGFLGEKV
Sbjct: 4561 GLSMGHLPTQTCIDEGGILTLLHALEGVSGENDIGARAENLLDTLADKEGKGDGFLGEKV 4620
Query: 13861 RALRDATKDXXXXXXXXXXXXXXQGLGMRQELSSDGGERIVVSQPILXXXXXXXXXXXXL 14040
RALRDATKD QGLGMRQELSSDGGERIVVSQPIL L
Sbjct: 4621 RALRDATKDEMRRRALRKREELLQGLGMRQELSSDGGERIVVSQPILEGFEDVEEEEDGL 4680
Query: 14041 ACMVCREGYKLRPSDLLGVYSYSKRVNLGVGNSGSARGECVYTTVSYFNIIHFQCHQEAK 14220
ACMVCREGYKLRPSDLLGVYSYSKRVNLGVGNSGSARGECVYTTVSYFNIIHFQCHQEAK
Sbjct: 4681 ACMVCREGYKLRPSDLLGVYSYSKRVNLGVGNSGSARGECVYTTVSYFNIIHFQCHQEAK 4740
Query: 14221 RADAALKNPKKEWEGAMLRNNESLCNSLFPVKGPSVPLAQYLRYVDQYWDNLNALGRADG 14400
RADAALKNPKKEWEGAMLRNNESLCNSLFPVKGPSVPLAQYLRYVDQYWDNLNALGRADG
Sbjct: 4741 RADAALKNPKKEWEGAMLRNNESLCNSLFPVKGPSVPLAQYLRYVDQYWDNLNALGRADG 4800
Query: 14401 SRLRLLTYDIVLMLARFATGASFSADCRGGGRDSNSRFLPFMFQMARHLLDQGGPVQRTN 14580
SRLRLLTYDIVLMLARFATGASFSADCRGGGRDSNSRFLPFMFQMARHLLDQGGPVQRTN
Sbjct: 4801 SRLRLLTYDIVLMLARFATGASFSADCRGGGRDSNSRFLPFMFQMARHLLDQGGPVQRTN 4860
Query: 14581 MXXXXXXXXXXXXXXXXXXXXXXXRPLTPGSQLSSTGTEETVQFMMVNSLLSESYESWLQ 14760
M RPLTPGSQLSSTGTEETVQFMMVNSLLSESYESWLQ
Sbjct: 4861 MARSVSSYISSSSTSTATAPSSDSRPLTPGSQLSSTGTEETVQFMMVNSLLSESYESWLQ 4920
Query: 14761 HRRVFLQRGIYHTFMQHAHGRVASRAAEPTSSGGKTQDAETLTGDELLSIVKPMLVYTGM 14940
HRRVFLQRGIYHTFMQHAHGRVASRAAEPTSSGGKTQDAETLTGDELLSIVKPMLVYTGM
Sbjct: 4921 HRRVFLQRGIYHTFMQHAHGRVASRAAEPTSSGGKTQDAETLTGDELLSIVKPMLVYTGM 4980
Query: 14941 IEQLQQLFKPKKPVHIEPIKKEG 15009
IEQLQQLFKPKKPVHIEPIKKEG
Sbjct: 4981 IEQLQQLFKPKKPVHIEPIKKEG 5003
>ref|NP_065816.1| retinoblastoma-associated factor 600 [Homo
sapiens]|gi|19070472|gb|AAL83880.1|AF348492_1
retinoblastoma-associated factor 600 [Homo sapiens]
Length = 5183
Score = 936 bits (2420), Expect = 0.0
Identities = 671/2224 (30%), Positives = 1066/2224 (47%), Gaps = 69/2224 (3%)
Frame = +1
Query: 8089 VTSSIPQASTPSIHVLEPGESAEFSASLTDPISISASKRAVNSLILSEFLQELSGWMETV 8268
V+SS ST + H G E + S V ++L LQ L + V
Sbjct: 2933 VSSSTGAISTTTGHQEGDGSEGEGEGETEGDVHTSNRLHMVRLMLLERLLQTLPQ-LRNV 2991
Query: 8269 SGVQAIPVMQLFYRLSSAIGGAFMDSSKPEEISLDKLIKWLLGEINLSKPFAA--STRSS 8442
GV+AIP MQ+ L++ + G + ++ +LD L+ L+ E+ + K + + RS+
Sbjct: 2992 GGVRAIPYMQVILMLTTDLDG----EDEKDKGALDNLLSQLIAELGMDKKDVSKKNERSA 3047
Query: 8443 LGEIVILVFMFFTLMLRSWHQPXXXXXXXXXXXXTDVHDRRIXXXXXXXXXXXXLHVQER 8622
L E+ ++V ++ + + E
Sbjct: 3048 LNEVHLVVMRLLSVFM------------------------------SRTKSGSKSSICES 3077
Query: 8623 DDFASQLVRACSCLRNQEFVNYLMNILQQLVHVFKSRAANVEARXXXXXXXXXAMLTVRR 8802
S A L + V+Y +++L+ L+ +KS+ + E +L
Sbjct: 3078 SSLISSATAAA--LLSSGAVDYCLHVLKSLLEYWKSQQNDEEP------VATSQLLKPHT 3129
Query: 8803 DLPAGNYSPFFSDSYAKAHRADIFVDYHRLLLENVFRLVYTLVRPEKQEKMGEKEKVYRN 8982
+ SPFF Y K H AD+F Y +LL E V RL Y + K+ N
Sbjct: 3130 TSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQI-----------KKITDTN 3178
Query: 8983 ASSKDLKLD-GFQDVLCSYINNPHTAFVRRYARRLFLHLCGSKTQYYSVRDSWQFSNEVK 9159
+ D + L Y+ T FVRR R+L L +CGSK +Y +RD + V+
Sbjct: 3179 SRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVR 3238
Query: 9160 NLYKHVEKSGGF----------ENNVSYERSVKIVKSLSTIAEVAVARPRNWQKYCLRHG 9309
+ K +E+ G F + + Y+ + +++ L AE+A R NWQK+C++
Sbjct: 3239 GIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTINWQKFCIKDD 3298
Query: 9310 DFLSFLLNGVFHFAEESVIQTLKLLNLAFYQGKDVS-------SSVQKAEATEVVTGSNR 9468
L FLL F E L+LL+ A K ++ SS + + V S +
Sbjct: 3299 SVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLAALAASSGSSSASSSSAPVAASSGQ 3358
Query: 9469 SGSQSVDSKKKKKGE------DGHDSGLEKLYVDMEGVVDIFSANCGDLLRQFIDFFLLE 9630
+ +QS S KK K E DG SG ++ + V + + L QF+ FLLE
Sbjct: 3359 ATTQSKSSTKKSKKEEKEKEKDGETSGSQEDQLCTALVNQLNKFADKETLIQFLRCFLLE 3418
Query: 9631 WNSSSVRTEAKSVIYGLWHHGRHSFKESLLAALLQKVRYLPAYGQNIVEYTELVSLLLDK 9810
NSSSVR +A + ++ + S +E LL + LPAYG+ ++ +L+ K
Sbjct: 3419 SNSSSVRWQAHCLTLHIYRNSSKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLK 3478
Query: 9811 APENNSKQAINELVDRCLNPDVIRCFFETLHSQNELIANHPNSRIYSTLGNLVEFDGYYL 9990
P+ K + E + + E L +QN ++ NHPNS IY+TL LVEFDGYYL
Sbjct: 3479 TPQTEKK--LKEYSQKAV---------EILRTQNHILTNHPNSNIYNTLSGLVEFDGYYL 3527
Query: 9991 ESEPCVACSSPDVPYSKMKLESLKSETKFTDNRIIVKCTGSYTIQSVTMNVHDARKSKSV 10170
ES+PC+ C++P+VP+ +KL S+K +T++T + +VK GS+TI VT+ + D +++K V
Sbjct: 3528 ESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMV 3587
Query: 10171 KVLNLYYNNRPVSDLSELKNNWSLWKRAKSCHLSFNQTELKVEFPIPITACNFMIELDSF 10350
+ +NLYYNNR V + ELKN + W +AK L+ QTE+K++ P+PI A N MIE F
Sbjct: 3588 RTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADF 3647
Query: 10351 YENLQALSLEPLQCPRCSRPVTDKHGICSNCHENAYQCRQCRNINYENLDSFLCNECGYS 10530
YEN QA S E LQCPRCS V G+C NC EN YQC +CR+INY+ D FLCN CG+
Sbjct: 3648 YENYQA-STETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFC 3706
Query: 10531 KYGRFEFNFMAKPSFIFDNMENDEDMKKGLAAIESESENAHKRYQQLLGFKKPLLKIVSS 10710
KY RF+F AKP D +EN+ED KK ++ I + + A + Y QL+G + L ++
Sbjct: 3707 KYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCK 3766
Query: 10711 IGETEMDSQHKDTVQQMMASLPGPSCKINRKIALLGVLYGEKCKAAFDSVSKSVQTLQGL 10890
+ E + D+ + S +NR I L Y CK +FD +SK +Q +
Sbjct: 3767 VNEAAPEKPQDDS--GTAGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFAS 3824
Query: 10891 RRVLMSY-LHQKNSNFSSGASRCVVSKT------------------PNNCYGCATTFVTQ 11013
R+ L+ Y L Q+ + ++ +SR V T CYGCA+
Sbjct: 3825 RKELLEYDLQQREA--ATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEH 3882
Query: 11014 CLEILQVLSKHPRSRKQLVAAGILSELFENNIHQGPKTARAQARAALSTFSEGDLSAVNE 11193
C+ +L+ L+ +P R LV+ G++ ELF+ N+ +G R + R + + + A +
Sbjct: 3883 CITLLRALATNPALRHILVSQGLIRELFDYNLRRGAAAMREEVRQLMCLLTRDNPEATQQ 3942
Query: 11194 LNNLVQKKIMYCLEHH-RSMDIALATREEMLLLSEVCSLTDEFWESRLRLVFQLLFSSIK 11370
+N+L+ K+ L+ H + D+A + + EMLLL++ S D WE RLR L ++
Sbjct: 3943 MNDLIIGKVSTALKSHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVN 4002
Query: 11371 LGAKHPAISEHIILPCLKIISVACTPPKPDTAEKEQTMGKSAPAVQEKDENAAGVIKYXX 11550
+ K P + E+I L CL+I+ PP P + + + ++ V+
Sbjct: 4003 I--KTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVKPYCNEI-------- 4052
Query: 11551 XXXXXXXXVSQKTRDIQLVSYLEWEKGASYLDFVRRQYKASQSIRG------ASQKSRTH 11712
Q +L+ + ASY +K IRG A KS
Sbjct: 4053 --------------HAQAQLWLKRDPKASY-----DAWKKCLPIRGIDGNGKAPSKSEL- 4092
Query: 11713 RSDFLALKYTLRWK----RRSSRTSKGGLQAFELGSWVTELILSACSQSIRSEMCTLISL 11880
R +L KY RWK RR RTS L+ +W+ +++ + +Q+ R CT++
Sbjct: 4093 RHLYLTEKYVWRWKQFLSRRGKRTSPLDLKLGH-NNWLRQVLFTPATQAARQAACTIVEA 4151
Query: 11881 LAAQSSPRRYRLINLLIGLLPATLAAGESSAEYFELLFKMIETQDALLFLTVRGCLTTIC 12060
LA S R+ ++++LL L AGE +AEY L K+I + ++L RG L +
Sbjct: 4152 LATIPS-RKQQVLDLLTSYLDELSIAGECAAEYLALYQKLITSAHWKVYLAARGVLPYVG 4210
Query: 12061 KLISQEVGNIESLER-SLQIDISQXXXXXXXXXXXXXXXXVPNIRSRFMRDNLLSHVLEA 12237
LI++E+ + +LE +L D+ Q V +I+ F + L+ VL
Sbjct: 4211 NLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHF-KSRLVGTVLNG 4269
Query: 12238 LIVIRGLIVQKTKLINDCNRRXXXXXXXXXXESSENKRQFIRACVSGLQTHAEENKGRTC 12417
+ +R L+VQ+TKLI++ + + F+ C+ + + ++ RT
Sbjct: 4270 YLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDY-RTP 4328
Query: 12418 LFILEQLCNLICPSKPEAV-YMLILNKSHTQEEFIRGSMTKNPYSSAE--IGPLMRDVKN 12588
+FI E+LC++I P + E + + L K QE+F++G M NPYSS E IGPLMRD+KN
Sbjct: 4329 VFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKN 4388
Query: 12589 KICQQXXXXXXXXXXXXXXXXVAGNIISLDLSIAQVYELVWKKSNQDCPPMTVTYRLQGL 12768
KICQ V IISLDL +A+VY+ VW +N+ PM + YR++GL
Sbjct: 4389 KICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEG-EPMRIVYRMRGL 4447
Query: 12769 DGEATEPMIKELEEDREESQDPEIEFAIAGAVREYGGLEILLDMIKSLQDDFKSNQEEMV 12948
G+ATE I+ L+ +E +D E + +AG + + GGLE +L+ + ++ DFK + +
Sbjct: 4448 LGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIR-DFKQGRHLLT 4506
Query: 12949 AVLDLLNHCCKIRENXXXXXXXXXXXXXXXXXXRAFSVDAMEP---------AEGILLIV 13101
+L L ++C K++ N ++ A + AE +L I+
Sbjct: 4507 VLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIM 4566
Query: 13102 ESLTLEANESDSISAAQSALTVSNEETGTWEQAKKIVLMFLERLSHPSGLKKSNKQQRNT 13281
E + L+ + ++ +S + L ++ + K ++M L++++ S +SN
Sbjct: 4567 E-IILDESNAEPLSEDKGNLLLTGD--------KDQLVMLLDQIN--STFVRSNPSV--L 4613
Query: 13282 EMVARILPYLTYGEPAAMEALIEHFSPYLQNWSEFDQLQQRHEEDPKDDSIAQQAAKQRF 13461
+ + RI+PYL++GE M+ L+E F PY FD+ + H D K
Sbjct: 4614 QGLLRIIPYLSFGEVEKMQILVERFKPY----CNFDKYDEDHSGDDK------------V 4657
Query: 13462 TVENFVRVSESLKTSSCGERLKDIVLENGIIAVAVKHIKEIFAITGQTGFKSSKEWLLAL 13641
++ F +++ +K +S G +LKD++L+ GI A+ ++K+ + W L
Sbjct: 4658 FLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAKNL---DADIWKKFL 4714
Query: 13642 KLPSVPLILSMLRGLSMGHLPTQTCIDEGGILTLLHALEGVSGENDIGARAENLLDTLAD 13821
P++P IL +LRGL++ H TQ I I LH LE VS + IG AENLL+ L +
Sbjct: 4715 SRPALPFILRLLRGLAIQHPGTQVLIGTDSIPN-LHKLEQVSSDEGIGTLAENLLEALRE 4773
Query: 13822 KEGKGDGFLGEKVRALRDATKDXXXXXXXXXXXXXXQGLGMRQELSSDGGERIVVSQPIL 14001
+ +K+ A R T+ LGM +++ G+ VV++ L
Sbjct: 4774 HPD-----VNKKIDAARRETRAEKKRMAMAMRQKALGTLGM---TTNEKGQ--VVTKTAL 4823
Query: 14002 XXXXXXXXXXXXLACMVCREGYKLRPSDLLGVYSYSKRVNLGVGNSGSARGECVYTTVSY 14181
L C +CREGYK +P+ +LG+Y+++KRV L R + Y+TVS+
Sbjct: 4824 LKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVAL-EEMENKPRKQQGYSTVSH 4882
Query: 14182 FNIIHFQCHQEAKRADAALKNPKKEWEGAMLRNNESLCNSLFPVKGPSVPLAQYLRYVDQ 14361
FNI+H+ CH A R L ++EWE A L+N + CN L PV GP VP + + + +
Sbjct: 4883 FNIVHYDCHLAAVR----LARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLAR 4938
Query: 14362 YWDNLNALGRADGSRLRLLTYDIVLMLARFATGASFSADCRGGGRDSNSRFLPFMFQMAR 14541
+ L +L +DI L+ RFA SFSAD GGGR+SN +P++
Sbjct: 4939 HNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVL 4998
Query: 14542 HLLD 14553
++L+
Sbjct: 4999 YVLN 5002
Score = 294 bits (753), Expect = 3e-77
Identities = 262/1089 (24%), Positives = 478/1089 (43%), Gaps = 77/1089 (7%)
Frame = +1
Query: 4663 SLDKEDEEDANS-ERYLASKVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHR 4839
++++ED + +S E L +K+CTFT + FM QHWY C+TC + G C+VCAKVCH+
Sbjct: 1641 AVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHK 1700
Query: 4840 GHRVVYSRSSRFFCDCGAGGVRGSSCQCLKPRKYNGNGSAPARGTNNFQSFLPLSEDADQ 5019
H + Y++ FFCDCGA SC L R + +G + + FQS +SE +
Sbjct: 1701 DHEISYAKYGSFFCDCGAK--EDGSCLALVKRTPS-SGMSSTMKESAFQSEPRISESLVR 1757
Query: 5020 LGESDSDVEEDGFGEENHVVLYIPKETQYKMSLLLEELGIEDR------------VLELF 5163
+ S ++ + V +E K SL G + VL++
Sbjct: 1758 HASTSSPADKAKVTISDGKVA--DEEKPKKSSLCRTVEGCREELQNQANFSFAPLVLDML 1815
Query: 5164 SSLLPSITSKRDS----GLSKEKQVNLGK----DKVLSFDTDLLQLKKAYKSGSLDLKIK 5319
+ L+ +I + G S Q L + +K + L+ + G+ + ++
Sbjct: 1816 NFLMDAIQTNFQQASAVGSSSRAQQALSELHTVEKAVEMTDQLMVPTLGSQEGAFE-NVR 1874
Query: 5320 ADYTNSKD--LKSLLANXXXXXXXXXXXXX------XXXXXGEGDKVAIFDVGQLIGQAT 5475
+Y+ + ++ L++ E K+ + + L+ QA
Sbjct: 1875 MNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQAD 1934
Query: 5476 IAPINADKANVKPLSRNIVRFEIVHLSFNPVVENYLAVAGLEDCQILTLNHRGEVIDRLA 5655
+ K + L+ V F ++ L+ NP E+YLAV GL+DC +LT + G V D L
Sbjct: 1935 SSK---RKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLV 1991
Query: 5656 VELALQ-GAFIRRIDWVPGSQVQLMVVTNKFVKIYDLSQDSISPTQYFTLPNDMIVDATL 5832
+ L G FI + W+PGSQ +L +VT FVKIYDL D++SPT YF LP+ I D T
Sbjct: 1992 LHPQLATGNFIIKAVWLPGSQTELSIVTADFVKIYDLCVDALSPTFYFLLPSSKIRDVTF 2051
Query: 5833 FVASRGRVFLLVLSEQGNLYRFELSWGGNAGATP--LKEIVQIMGKD-------VTGKGS 5985
G+ ++++S G +Y + +A P + +++I +D V G G
Sbjct: 2052 LFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEINHEDLKDSNSQVAGGGV 2111
Query: 5986 SVYFSPTYRLLFISYHDGSSFMGRXXXXXXXXXXXXGMFEEESDCKQRVA-GLHRWKELL 6162
SVY+S ++LF SY G SF + + S+ + + L +W E++
Sbjct: 2112 SVYYSHVLQMLFFSYCQGKSFAATISRTTLEVLQLFPINIKSSNGGSKTSPALCQWSEVM 2171
Query: 6163 AGSGLFICFSSVKSNAVLAVSLRGDGVCAQNLRHPTGSSS--PMVGITAYKPLSKDNVHC 6336
GL C + L V ++ D Q ++ + MV I +
Sbjct: 2172 NHPGLVCCVQQT-TGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTM 2230
Query: 6337 LVLHDDGSLQIYSH--------VRSGVDTDSNFTAEK-VKKLGSKILNNKTYAGAKPEFP 6489
++L +DGSL+IY ++ + S + K V+K + + +T ++ FP
Sbjct: 2231 ILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKTATITTRT--SSQVTFP 2288
Query: 6490 LDFFERAFCITADVRLGSDAIRNGDSEGAKQSLASEDGFIESPSPVGFKISVSNPNPDIV 6669
+DFFE +T G+D ++ +++ K L S ++ + P GF I +SN N +V
Sbjct: 2289 IDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEISNNNSTMV 2348
Query: 6670 MVGIRMHVGTTSASSIPSEVTIFQRSIKMDEGMRCWYDIPFTVAESLLADEDVVISVGPT 6849
M G+R+ +GT + PS + IF R+++++ W+D PFT E+L AD+ + + +G +
Sbjct: 2349 MTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADKKLNLFIGAS 2408
Query: 6850 TSGTALPRIDSLEVYGRAKDEFGWKEK------MDAVLDMEARVLGHGLLLPGSSKKRAL 7011
+ ID++++YG+ K++FGW ++ +V ++ L S
Sbjct: 2409 VEPAGVTMIDAVKIYGKTKEQFGWPDEPPEEFPSASVSNICPSNLNQSNGTGDSDSAAPT 2468
Query: 7012 AQSASMEEQVIADGLKLLSIYYSVCRPRQEVVLSELKCKQLLETIFESDRETLLQTTACR 7191
S ++ E+++ L+ L ++V P E ++ ++L + +Q +
Sbjct: 2469 TTSGTVLERLVVSSLEALESCFAV-GPIIEKERNKNAAQELATLLLSLPAPASVQQQSKS 2527
Query: 7192 VLQSVFPRKEIYYQ----------VMFLPNSVKDTMRLLGVVKVTSILSSRLGILGTGGS 7341
+L S+ + Y+ V L S K+ L V ++++R + +
Sbjct: 2528 LLASLHTSRSAYHSHKDQALLSKAVQCLNTSSKEGKDLDPEVFQRLVITARSIAIMRPNN 2587
Query: 7342 IVEEFNAQMRAVSKVALTRKSNFSVFLEMNGSEVVDNLMQVLWGILESEPLDT------- 7500
+V +++ + + LE + + L+ W + S+P +
Sbjct: 2588 LVHFTESKLPQMETEGMDEGKEPQKQLEGDCCSFITQLVNHFWKLHASKPKNAFLAPACL 2647
Query: 7501 PTMNNV---VMSSVELIYSYAECLASQGKDTGVHSVAPAVQLLKALMLFPNESVQTSSRC 7671
P + ++ V + V++I+ Y C + + A ++ ++L P+ +V S +
Sbjct: 2648 PGLTHIEATVNALVDIIHGYCTC--------ELDCINTASKIYMQMLLCPDPAVSFSCKQ 2699
Query: 7672 VLVLAISSR 7698
L+ + R
Sbjct: 2700 ALIRVLRPR 2708
>pir||T00076 hypothetical protein KIAA0462 - human
(fragment)|gi|3413886|dbj|BAA32307.1| KIAA0462 protein
[Homo sapiens]
Length = 2276
Score = 936 bits (2419), Expect = 0.0
Identities = 671/2224 (30%), Positives = 1066/2224 (47%), Gaps = 69/2224 (3%)
Frame = +1
Query: 8089 VTSSIPQASTPSIHVLEPGESAEFSASLTDPISISASKRAVNSLILSEFLQELSGWMETV 8268
V+SS ST + H G E + S V ++L LQ L + V
Sbjct: 26 VSSSTGAISTTTGHQEGDGSEGEGEGETEGDVHTSNRLHMVRLMLLERLLQTLPQ-LRNV 84
Query: 8269 SGVQAIPVMQLFYRLSSAIGGAFMDSSKPEEISLDKLIKWLLGEINLSKPFAA--STRSS 8442
GV+AIP MQ+ L++ + G + ++ +LD L+ L+ E+ + K + + RS+
Sbjct: 85 GGVRAIPYMQVILMLTTDLDG----EDEKDKGALDNLLSQLIAELGMDKKDVSKKNERSA 140
Query: 8443 LGEIVILVFMFFTLMLRSWHQPXXXXXXXXXXXXTDVHDRRIXXXXXXXXXXXXLHVQER 8622
L E+ ++V ++ + + E
Sbjct: 141 LNEVHLVVMRLLSVFM------------------------------SRTKSGSKSSICES 170
Query: 8623 DDFASQLVRACSCLRNQEFVNYLMNILQQLVHVFKSRAANVEARXXXXXXXXXAMLTVRR 8802
S A L + V+Y +++L+ L+ +KS+ + E +L
Sbjct: 171 SSLISSATAAA--LLSSGAVDYCLHVLKSLLEYWKSQQNDEEP------VATSQLLKPHT 222
Query: 8803 DLPAGNYSPFFSDSYAKAHRADIFVDYHRLLLENVFRLVYTLVRPEKQEKMGEKEKVYRN 8982
+ SPFF Y K H AD+F Y +LL E V RL Y + K+ N
Sbjct: 223 TSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQI-----------KKITDTN 271
Query: 8983 ASSKDLKLD-GFQDVLCSYINNPHTAFVRRYARRLFLHLCGSKTQYYSVRDSWQFSNEVK 9159
+ D + L Y+ T FVRR R+L L +CGSK +Y +RD + V+
Sbjct: 272 SRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVR 331
Query: 9160 NLYKHVEKSGGF----------ENNVSYERSVKIVKSLSTIAEVAVARPRNWQKYCLRHG 9309
+ K +E+ G F + + Y+ + +++ L AE+A R NWQK+C++
Sbjct: 332 GIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTINWQKFCIKDD 391
Query: 9310 DFLSFLLNGVFHFAEESVIQTLKLLNLAFYQGKDVS-------SSVQKAEATEVVTGSNR 9468
L FLL F E L+LL+ A K ++ SS + + V S +
Sbjct: 392 SVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLAALAASSGSSSASSSSAPVAASSGQ 451
Query: 9469 SGSQSVDSKKKKKGE------DGHDSGLEKLYVDMEGVVDIFSANCGDLLRQFIDFFLLE 9630
+ +QS S KK K E DG SG ++ + V + + L QF+ FLLE
Sbjct: 452 ATTQSKSSTKKSKKEEKEKEKDGETSGSQEDQLCTALVNQLNKFADKETLIQFLRCFLLE 511
Query: 9631 WNSSSVRTEAKSVIYGLWHHGRHSFKESLLAALLQKVRYLPAYGQNIVEYTELVSLLLDK 9810
NSSSVR +A + ++ + S +E LL + LPAYG+ ++ +L+ K
Sbjct: 512 SNSSSVRWQAHCLTLHIYRNSSKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLK 571
Query: 9811 APENNSKQAINELVDRCLNPDVIRCFFETLHSQNELIANHPNSRIYSTLGNLVEFDGYYL 9990
P+ K + E + + E L +QN ++ NHPNS IY+TL LVEFDGYYL
Sbjct: 572 TPQTEKK--LKEYSQKAV---------EILRTQNHILTNHPNSNIYNTLSGLVEFDGYYL 620
Query: 9991 ESEPCVACSSPDVPYSKMKLESLKSETKFTDNRIIVKCTGSYTIQSVTMNVHDARKSKSV 10170
ES+PC+ C++P+VP+ +KL S+K +T++T + +VK GS+TI VT+ + D +++K V
Sbjct: 621 ESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMV 680
Query: 10171 KVLNLYYNNRPVSDLSELKNNWSLWKRAKSCHLSFNQTELKVEFPIPITACNFMIELDSF 10350
+ +NLYYNNR V + ELKN + W +AK L+ QTE+K++ P+PI A N MIE F
Sbjct: 681 RTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADF 740
Query: 10351 YENLQALSLEPLQCPRCSRPVTDKHGICSNCHENAYQCRQCRNINYENLDSFLCNECGYS 10530
YEN QA S E LQCPRCS V G+C NC EN YQC +CR+INY+ D FLCN CG+
Sbjct: 741 YENYQA-STETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFC 799
Query: 10531 KYGRFEFNFMAKPSFIFDNMENDEDMKKGLAAIESESENAHKRYQQLLGFKKPLLKIVSS 10710
KY RF+F AKP D +EN+ED KK ++ I + + A + Y QL+G + L ++
Sbjct: 800 KYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCK 859
Query: 10711 IGETEMDSQHKDTVQQMMASLPGPSCKINRKIALLGVLYGEKCKAAFDSVSKSVQTLQGL 10890
+ E + D+ + S +NR I L Y CK +FD +SK +Q +
Sbjct: 860 VNEAAPEKPQDDS--GTAGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFAS 917
Query: 10891 RRVLMSY-LHQKNSNFSSGASRCVVSKT------------------PNNCYGCATTFVTQ 11013
R+ L+ Y L Q+ + ++ +SR V T CYGCA+
Sbjct: 918 RKELLEYDLQQREA--ATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEH 975
Query: 11014 CLEILQVLSKHPRSRKQLVAAGILSELFENNIHQGPKTARAQARAALSTFSEGDLSAVNE 11193
C+ +L+ L+ +P R LV+ G++ ELF+ N+ +G R + R + + + A +
Sbjct: 976 CITLLRALATNPALRHILVSQGLIRELFDYNLRRGAAAMREEVRQLMCLLTRDNPEATQQ 1035
Query: 11194 LNNLVQKKIMYCLE-HHRSMDIALATREEMLLLSEVCSLTDEFWESRLRLVFQLLFSSIK 11370
+N+L+ K+ L+ H + D+A + + EMLLL++ S D WE RLR L ++
Sbjct: 1036 MNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVN 1095
Query: 11371 LGAKHPAISEHIILPCLKIISVACTPPKPDTAEKEQTMGKSAPAVQEKDENAAGVIKYXX 11550
+ K P + E+I L CL+I+ PP P + + + ++ V+
Sbjct: 1096 I--KTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVKPYCNEI-------- 1145
Query: 11551 XXXXXXXXVSQKTRDIQLVSYLEWEKGASYLDFVRRQYKASQSIRG------ASQKSRTH 11712
Q +L+ + ASY +K IRG A KS
Sbjct: 1146 --------------HAQAQLWLKRDPKASY-----DAWKKCLPIRGIDGNGKAPSKSEL- 1185
Query: 11713 RSDFLALKYTLRWK----RRSSRTSKGGLQAFELGSWVTELILSACSQSIRSEMCTLISL 11880
R +L KY RWK RR RTS L+ +W+ +++ + +Q+ R CT++
Sbjct: 1186 RHLYLTEKYVWRWKQFLSRRGKRTSPLDLKLGH-NNWLRQVLFTPATQAARQAACTIVEA 1244
Query: 11881 LAAQSSPRRYRLINLLIGLLPATLAAGESSAEYFELLFKMIETQDALLFLTVRGCLTTIC 12060
LA S R+ ++++LL L AGE +AEY L K+I + ++L RG L +
Sbjct: 1245 LATIPS-RKQQVLDLLTSYLDELSIAGECAAEYLALYQKLITSAHWKVYLAARGVLPYVG 1303
Query: 12061 KLISQEVGNIESLER-SLQIDISQXXXXXXXXXXXXXXXXVPNIRSRFMRDNLLSHVLEA 12237
LI++E+ + +LE +L D+ Q V +I+ F + L+ VL
Sbjct: 1304 NLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHF-KSRLVGTVLNG 1362
Query: 12238 LIVIRGLIVQKTKLINDCNRRXXXXXXXXXXESSENKRQFIRACVSGLQTHAEENKGRTC 12417
+ +R L+VQ+TKLI++ + + F+ C+ + + ++ RT
Sbjct: 1363 YLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDY-RTP 1421
Query: 12418 LFILEQLCNLICPSKPEAV-YMLILNKSHTQEEFIRGSMTKNPYSSAE--IGPLMRDVKN 12588
+FI E+LC++I P + E + + L K QE+F++G M NPYSS E IGPLMRD+KN
Sbjct: 1422 VFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKN 1481
Query: 12589 KICQQXXXXXXXXXXXXXXXXVAGNIISLDLSIAQVYELVWKKSNQDCPPMTVTYRLQGL 12768
KICQ V IISLDL +A+VY+ VW +N+ PM + YR++GL
Sbjct: 1482 KICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEG-EPMRIVYRMRGL 1540
Query: 12769 DGEATEPMIKELEEDREESQDPEIEFAIAGAVREYGGLEILLDMIKSLQDDFKSNQEEMV 12948
G+ATE I+ L+ +E +D E + +AG + + GGLE +L+ + ++ DFK + +
Sbjct: 1541 LGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIR-DFKQGRHLLT 1599
Query: 12949 AVLDLLNHCCKIRENXXXXXXXXXXXXXXXXXXRAFSVDAMEP---------AEGILLIV 13101
+L L ++C K++ N ++ A + AE +L I+
Sbjct: 1600 VLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIM 1659
Query: 13102 ESLTLEANESDSISAAQSALTVSNEETGTWEQAKKIVLMFLERLSHPSGLKKSNKQQRNT 13281
E + L+ + ++ +S + L ++ + K ++M L++++ S +SN
Sbjct: 1660 E-IILDESNAEPLSEDKGNLLLTGD--------KDQLVMLLDQIN--STFVRSNPSV--L 1706
Query: 13282 EMVARILPYLTYGEPAAMEALIEHFSPYLQNWSEFDQLQQRHEEDPKDDSIAQQAAKQRF 13461
+ + RI+PYL++GE M+ L+E F PY FD+ + H D K
Sbjct: 1707 QGLLRIIPYLSFGEVEKMQILVERFKPY----CNFDKYDEDHSGDDK------------V 1750
Query: 13462 TVENFVRVSESLKTSSCGERLKDIVLENGIIAVAVKHIKEIFAITGQTGFKSSKEWLLAL 13641
++ F +++ +K +S G +LKD++L+ GI A+ ++K+ + W L
Sbjct: 1751 FLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAKNL---DADIWKKFL 1807
Query: 13642 KLPSVPLILSMLRGLSMGHLPTQTCIDEGGILTLLHALEGVSGENDIGARAENLLDTLAD 13821
P++P IL +LRGL++ H TQ I I LH LE VS + IG AENLL+ L +
Sbjct: 1808 SRPALPFILRLLRGLAIQHPGTQVLIGTDSIPN-LHKLEQVSSDEGIGTLAENLLEALRE 1866
Query: 13822 KEGKGDGFLGEKVRALRDATKDXXXXXXXXXXXXXXQGLGMRQELSSDGGERIVVSQPIL 14001
+ +K+ A R T+ LGM +++ G+ VV++ L
Sbjct: 1867 HPD-----VNKKIDAARRETRAEKKRMAMAMRQKALGTLGM---TTNEKGQ--VVTKTAL 1916
Query: 14002 XXXXXXXXXXXXLACMVCREGYKLRPSDLLGVYSYSKRVNLGVGNSGSARGECVYTTVSY 14181
L C +CREGYK +P+ +LG+Y+++KRV L R + Y+TVS+
Sbjct: 1917 LKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVAL-EEMENKPRKQQGYSTVSH 1975
Query: 14182 FNIIHFQCHQEAKRADAALKNPKKEWEGAMLRNNESLCNSLFPVKGPSVPLAQYLRYVDQ 14361
FNI+H+ CH A R L ++EWE A L+N + CN L PV GP VP + + + +
Sbjct: 1976 FNIVHYDCHLAAVR----LARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLAR 2031
Query: 14362 YWDNLNALGRADGSRLRLLTYDIVLMLARFATGASFSADCRGGGRDSNSRFLPFMFQMAR 14541
+ L +L +DI L+ RFA SFSAD GGGR+SN +P++
Sbjct: 2032 HNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVL 2091
Query: 14542 HLLD 14553
++L+
Sbjct: 2092 YVLN 2095
>ref|XP_233595.1| similar to retinoblastoma-associated factor 600 [Homo sapiens] [Rattus
norvegicus]
Length = 5187
Score = 897 bits (2318), Expect = 0.0
Identities = 623/2057 (30%), Positives = 997/2057 (48%), Gaps = 99/2057 (4%)
Frame = +1
Query: 8680 VNYLMNILQQLVHVFKSRAANVEARXXXXXXXXXAMLTVRRDLPAGNYSPFFSDSYAKAH 8859
V+Y +++L+ L+ +K + + E +L + SPFF Y K H
Sbjct: 3066 VDYCLHVLKSLLEYWKGQQSEEEP------VTTSQLLKPHTTSSPPDMSPFFLRQYVKGH 3119
Query: 8860 RADIFVDYHRLLLENVFRLVYTLVRPEKQEKMGEKEKVYRNASSK---DLKLDGFQDVLC 9030
AD+F Y +LL E V RL Y + K + SS+ + + L
Sbjct: 3120 AADVFEAYTQLLTEMVLRLPYQI-------------KKIADTSSRIPPPVFDHSWFYFLS 3166
Query: 9031 SYINNPHTAFVRRYARRLFLHLCGSKTQYYSVRDSWQFSNEVKNLYKHVEKSGGF----- 9195
Y+ T FVRR R+L L +CGSK +Y +RD + V+ + K +E+ G F
Sbjct: 3167 EYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASV 3226
Query: 9196 -----ENNVSYERSVKIVKSLSTIAEVAVARPRNWQKYCLRHGDFLSFLLNGVFHFAEES 9360
+ + Y+ + +++ L AE+A R NWQK+C++ L FLL F E
Sbjct: 3227 VTASSGSALQYDTLISLMEHLKACAEIAAQRTINWQKFCIKDDSVLYFLLQVSFLVDEGV 3286
Query: 9361 VIQTLKLLNLAFYQGK------------DVSSSVQKAEATEVVTGSNRSGSQSVDSKKKK 9504
L+LL+ A K V+SS A ++ T ++S ++ ++K+
Sbjct: 3287 SPVLLQLLSCALCGSKVLAALAASTGSSSVASSAPPAASSGQTTTQSKSSTKKSKKEEKE 3346
Query: 9505 KGEDGHDSGLEKLYVDMEGVVDIFSANCGDLLRQFIDFFLLEWNSSSVRTEAKSVIYGLW 9684
K ++G SG ++ + V + + L QF+ FLLE NSSSVR +A + ++
Sbjct: 3347 KEKEGESSGSQEDQLCTALVNQLNRFADKETLIQFLRCFLLESNSSSVRWQAHCLTLHIY 3406
Query: 9685 HHGRHSFKESLLAALLQKVRYLPAYGQNIVEYTELVSLLLDKAPENNSKQAINELVDRCL 9864
+ + +E LL + LPAYG+ ++ +L+ K + K + E + +
Sbjct: 3407 RNSNKAQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTAQTEKK--LKEYSQKAV 3464
Query: 9865 NPDVIRCFFETLHSQNELIANHPNSRIY-------------------------------- 9948
E L +QN ++ NHPNS IY
Sbjct: 3465 ---------EILRTQNHILTNHPNSNIYNPFPYTYAQGPGEGDGSGMVLEGDFAETQTPF 3515
Query: 9949 --STLGNLVEFDGYYLESEPCVACSSPDVPYSKMKLESLKSETKFTDNRIIVKCTGSYTI 10122
STL LVEFDGYYLES+PC+ C++P+VP+ +KL S+K +T++T + +VK GS+TI
Sbjct: 3516 FPSTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTI 3575
Query: 10123 QSVTMNVHDARKSKSVKVLNLYYNNRPVSDLSELKNNWSLWKRAKSCHLSFNQTELKVEF 10302
VT+ + D +++K V+ +NLYYNNR V + ELKN + W +AK L+ QTE+K++
Sbjct: 3576 SKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDL 3635
Query: 10303 PIPITACNFMIELDSFYENLQALSLEPLQCPRCSRPVTDKHGICSNCHENAYQCRQCRNI 10482
P+PI A N MIE FYEN QA S E LQCPRCS V G+C NC EN YQC +CR+I
Sbjct: 3636 PLPIVASNLMIEFADFYENYQA-STETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSI 3694
Query: 10483 NYENLDSFLCNECGYSKYGRFEFNFMAKPSFIFDNMENDEDMKKGLAAIESESENAHKRY 10662
NY+ D FLCN CG+ KY RF+F AKP D +EN+ED KK ++ I + + A + Y
Sbjct: 3695 NYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVY 3754
Query: 10663 QQLLGFKKPLLKIVSSIGETEMDSQH----KDTVQQMMASLPGPSCKINRKIALLGVLYG 10830
QL+G + L ++ + E + + + S +NR I L Y
Sbjct: 3755 HQLMGHRPQLENLLCKVNEAAPEKPQVLPDRREDSGTAGGISSTSASVNRYILQLAQEYC 3814
Query: 10831 EKCKAAFDSVSKSVQTLQGLRRVLMSY-LHQKNS-----------NFSSGASRCVVSKTP 10974
CK +FD +SK +Q + R+ L+ Y L Q+ + F++ RC + +
Sbjct: 3815 GDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRCGHTSS- 3873
Query: 10975 NNCYGCATTFVTQCLEILQVLSKHPRSRKQLVAAGILSELFENNIHQGPKTARAQARAAL 11154
CYGCA+ C+ +L+ L+ +P R LV+ G++ ELF+ N+ +G R + R +
Sbjct: 3874 TKCYGCASAVTEHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGAAAIREEVRQLM 3933
Query: 11155 STFSEGDLSAVNELNNLVQKKIMYCLEHH-RSMDIALATREEMLLLSEVCSLTDEFWESR 11331
+ + A ++N+L+ K+ L+ H + D+A + + EMLLL++ S D WE R
Sbjct: 3934 CLLTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELR 3993
Query: 11332 LRLVFQLLFSSIKLGAKHPAISEHIILPCLKIISVACTPPKPDTAEKEQTMGKSAPAVQE 11511
LR L ++ + K P + E+I L CL+I+ PP P + + + ++ V+
Sbjct: 3994 LRCALSLFLMAVNI--KTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVKP 4051
Query: 11512 KDENAAGVIKYXXXXXXXXXXVSQKTRDIQLVSYLEWEKGASYLDFVRRQYKASQSIRGA 11691
Q +L+ + ASY +K IRG
Sbjct: 4052 YCNEIHA----------------------QAQLWLKRDPKASY-----EAWKKCLPIRGV 4084
Query: 11692 S------QKSRTHRSDFLALKYTLRWK----RRSSRTSKGGLQAFELGSWVTELILSACS 11841
KS HR +L KY RWK RR RT+ L+ +W+ +++ + +
Sbjct: 4085 DGNGKSPSKSELHRL-YLTEKYVWRWKQFLSRRGKRTTPLDLKLGH-NNWLRQVLFTPAT 4142
Query: 11842 QSIRSEMCTLISLLAAQSSPRRYRLINLLIGLLPATLAAGESSAEYFELLFKMIETQDAL 12021
Q+ R CT++ LA S R+ ++++LL L AGE +AEY L K+I +
Sbjct: 4143 QAARQAACTIVEALATVPS-RKQQVLDLLTSYLDELSVAGECAAEYLALYQKLIASCHWK 4201
Query: 12022 LFLTVRGCLTTICKLISQEVGNIESLERS-LQIDISQXXXXXXXXXXXXXXXXVPNIRSR 12198
++L RG L + LI++E+ + +LE + L D+ Q V +I+
Sbjct: 4202 VYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRH 4261
Query: 12199 FMRDNLLSHVLEALIVIRGLIVQKTKLINDCNRRXXXXXXXXXXESSENKRQFIRACVSG 12378
F + L+ VL + +R L++Q+TKLI++ + + F+ C+
Sbjct: 4262 F-KSRLVGTVLNGYLCLRKLVLQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIET 4320
Query: 12379 LQTHAEENKGRTCLFILEQLCNLICPSKPEAV-YMLILNKSHTQEEFIRGSMTKNPYSSA 12555
+ + ++ RT +FI E+LC++I P + E + + L K QE+F++G M NPYSS
Sbjct: 4321 AKRYNLDDY-RTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSN 4379
Query: 12556 E--IGPLMRDVKNKICQQXXXXXXXXXXXXXXXXVAGNIISLDLSIAQVYELVWKKSNQD 12729
E IGPLMRD+KNKICQ V IISLDL +A+VY+ VW +N+
Sbjct: 4380 EPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEG 4439
Query: 12730 CPPMTVTYRLQGLDGEATEPMIKELEEDREESQDPEIEFAIAGAVREYGGLEILLDMIKS 12909
PM + YR++GL G+ATE I+ L+ +E +D E + +AG + + GGL+ +L+ +
Sbjct: 4440 -EPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYRMAGVMAQCGGLQCMLNRLAG 4498
Query: 12910 LQDDFKSNQEEMVAVLDLLNHCCKIRENXXXXXXXXXXXXXXXXXXRAFSVDAMEP---- 13077
++ DFK + + +L L ++C K++ N ++ A +
Sbjct: 4499 VK-DFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDS 4557
Query: 13078 -----AEGILLIVESLTLEANESDSISAAQSALTVSNEETGTWEQAKKIVLMFLERLSHP 13242
AE +L I+E + L+ + ++ +S + L ++ + K ++M L++++
Sbjct: 4558 GGAAVAEQVLSIME-IILDESNAEPLSEDKGNLLLTGD--------KDQLVMLLDQIN-- 4606
Query: 13243 SGLKKSNKQQRNTEMVARILPYLTYGEPAAMEALIEHFSPYLQNWSEFDQLQQRHEEDPK 13422
S +SN + + RI+PYL++GE M+ L+E F PY FD+ + H D K
Sbjct: 4607 STFVRSNPSV--LQGLLRIIPYLSFGEVEKMQILVERFKPY----CSFDKYDEDHSGDDK 4660
Query: 13423 DDSIAQQAAKQRFTVENFVRVSESLKTSSCGERLKDIVLENGIIAVAVKHIKEIFAITGQ 13602
++ F +++ +K +S G +LKD++L+ GI A+ ++K+
Sbjct: 4661 ------------VFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQSALDYMKKHIPSAKN 4708
Query: 13603 TGFKSSKEWLLALKLPSVPLILSMLRGLSMGHLPTQTCIDEGGILTLLHALEGVSGENDI 13782
+ W L P++P IL +LRGL+M H TQ I I T LH LE VS + I
Sbjct: 4709 L---DADIWKKFLSRPALPFILRLLRGLAMQHPATQVLIGTDSI-TSLHKLEQVSSDEGI 4764
Query: 13783 GARAENLLDTLADKEGKGDGFLGEKVRALRDATKDXXXXXXXXXXXXXXQGLGMRQELSS 13962
G AENLL+ L + + +K+ A R T+ LGM ++
Sbjct: 4765 GTLAENLLEALREHPD-----VNKKIDAARRETRAEKKRMAMAMRQKALGTLGM---TTN 4816
Query: 13963 DGGERIVVSQPILXXXXXXXXXXXXLACMVCREGYKLRPSDLLGVYSYSKRVNLGVGNSG 14142
+ G+ VV++ L L C +CREGYK +P+ +LG+Y+++KRV L
Sbjct: 4817 EKGQ--VVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVAL-EEMEN 4873
Query: 14143 SARGECVYTTVSYFNIIHFQCHQEAKRADAALKNPKKEWEGAMLRNNESLCNSLFPVKGP 14322
R + Y+TVS+FNI+H+ CH A R L ++EWE A L+N + CN L PV GP
Sbjct: 4874 KPRKQQGYSTVSHFNIVHYDCHLAAVR----LARGREEWESAALQNANTKCNGLLPVWGP 4929
Query: 14323 SVPLAQYLRYVDQYWDNLNALGRADGSRLRLLTYDIVLMLARFATGASFSADCRGGGRDS 14502
VP + + + ++ L +L +DI L+ RFA SFSAD GGGR+S
Sbjct: 4930 HVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRES 4989
Query: 14503 NSRFLPFMFQMARHLLD 14553
N +P++ ++L+
Sbjct: 4990 NIHLIPYIIHTVLYVLN 5006
Score = 293 bits (751), Expect = 4e-77
Identities = 221/809 (27%), Positives = 383/809 (47%), Gaps = 53/809 (6%)
Frame = +1
Query: 4663 SLDKEDEEDANS-ERYLASKVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHR 4839
++++ED + +S E L +K+CTFT + FM QHWY C+TC + G C+VCAKVCH+
Sbjct: 1622 AVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHK 1681
Query: 4840 GHRVVYSRSSRFFCDCGAGGVRGSSCQCLKPRKYNGNGSAPARGTNNFQSFLPLSE---- 5007
H + Y++ FFCDCGA SC L R + +G + + FQS +SE
Sbjct: 1682 DHEISYAKYGSFFCDCGAK--EDGSCLALVKRTPS-SGMSSTMKESAFQSEPRVSESLVR 1738
Query: 5008 -------DADQLGESDSDVEEDGFGEENHVVLYIP---KETQYKMSLLLEELGIEDRVLE 5157
D ++ SD V ++ +++ + + +E Q + + L VL+
Sbjct: 1739 HASTSPADKAKVTISDGKVADEEKPKKSSLCRTVEGCREELQNQANFSFAPL-----VLD 1793
Query: 5158 LFSSLLPSITSKRDS----GLSKEKQVNLGK----DKVLSFDTDLLQLKKAYKSGSLDLK 5313
+ + L+ +I + G S Q L + DKV+ L+ + G+ +
Sbjct: 1794 MLNFLMDAIQTNFQQASAVGSSSRAQQALSELHTVDKVVEMTDQLMVPTLGSQEGAFE-N 1852
Query: 5314 IKADYTNSKD--LKSLLANXXXXXXXXXXXXX------XXXXXGEGDKVAIFDVGQLIGQ 5469
++ +Y+ + ++ L++ E K+ + + L+ Q
Sbjct: 1853 VRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQ 1912
Query: 5470 ATIAPINADKANVKPLSRNIVRFEIVHLSFNPVVENYLAVAGLEDCQILTLNHRGEVIDR 5649
A + K + L+ V F ++ L+ NP E+YLAV GL+DC +LT + G V D
Sbjct: 1913 ADSSK---RKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDH 1969
Query: 5650 LAVELALQ-GAFIRRIDWVPGSQVQLMVVTNKFVKIYDLSQDSISPTQYFTLPNDMIVDA 5826
L + L G FI + W+PGSQ +L +VT FVKIYDLS D++SPT YF LP+ I D
Sbjct: 1970 LVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFLLPSSKIRDV 2029
Query: 5827 TLFVASRGRVFLLVLSEQGNLYRFELSWGGNAGATP--LKEIVQIMGKD-------VTGK 5979
T G+ ++++S G +Y + +A P + +++I +D V G
Sbjct: 2030 TFLFNEEGKNIIVIMSSAGYMYTQLMEEASSAQQGPFYVTNVLEINHEDLKDSNSQVAGG 2089
Query: 5980 GSSVYFSPTYRLLFISYHDGSSFMGRXXXXXXXXXXXXGMFEEESDCKQRVA-GLHRWKE 6156
G SVY+S ++LF SY G SF + + S+ + + L +W E
Sbjct: 2090 GVSVYYSHVLQMLFFSYSQGKSFAATVSRSTLEVLQLFPINIKSSNGGSKTSPALCQWSE 2149
Query: 6157 LLAGSGLFICFSSVKSNAVLAVSLRGDGVCAQNLRHPTGSSS--PMVGITAYKPLSKDNV 6330
++ GL C + L V ++ D Q ++ + MV I +
Sbjct: 2150 VMNHPGLVCCVQQT-TGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRT 2208
Query: 6331 HCLVLHDDGSLQIYSH--------VRSGVDTDSNFTAEK-VKKLGSKILNNKTYAGAKPE 6483
++L +DGSL+IY ++ + S + K V+K + + +T ++
Sbjct: 2209 TMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKTATITART--SSQVT 2266
Query: 6484 FPLDFFERAFCITADVRLGSDAIRNGDSEGAKQSLASEDGFIESPSPVGFKISVSNPNPD 6663
FP+DFFE +T G+D ++ +++ K L S ++ + P GF + +SN +
Sbjct: 2267 FPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTMEISNNSST 2326
Query: 6664 IVMVGIRMHVGTTSASSIPSEVTIFQRSIKMDEGMRCWYDIPFTVAESLLADEDVVISVG 6843
+VM G+R+ +GT + PS + IF R+++++ W+D PFT E+L AD + + +G
Sbjct: 2327 MVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADRKLNLFIG 2386
Query: 6844 PTTSGTALPRIDSLEVYGRAKDEFGWKEK 6930
+ + ID++++YG+ K++FGW ++
Sbjct: 2387 ASVDPAGVTMIDAVKIYGKTKEQFGWPDE 2415
>gb|EAA01010.1| ebiP4133 [Anopheles gambiae str. PEST]
Length = 5432
Score = 786 bits (2031), Expect = 0.0
Identities = 650/2412 (26%), Positives = 1069/2412 (43%), Gaps = 100/2412 (4%)
Frame = +1
Query: 8011 VESLGADTNEIQFSADEVGISNMLPVVTSSIPQASTPSIHVLEPGESAEFSASLTDPISI 8190
VES+G + ++ S V +P S + +AE +S D
Sbjct: 3066 VESIGGTSGRSSTYEEQPNPSPPRTSVVDQMPSQSAGAATTSAQAPAAEAESS--DASGE 3123
Query: 8191 SASK-RAVNSLILSEFLQELSGWMETVSGVQAIPVMQLFYRLSSAIGGAFMDSSKPEEIS 8367
+A+K + IL++ ++ S ++TVSG Q IP MQ+ L+S + G + +
Sbjct: 3124 TANKLHGLRCSILNQLVENFSA-LDTVSGAQCIPFMQVILMLTSDLDGTQEADQQALSLL 3182
Query: 8368 LDKLIKWLLGEINLSKPFAASTRSSLGEIVILVFMFFTLML---RSWHQPXXXXXXXXXX 8538
L LI L EI +K + + R+ E+ ++V +++ +S
Sbjct: 3183 LQALIDRL--EIPSTKMYEMANRNPKTEVQLVVLRLIGVLMGKVKSKSSSSSSSAGTSGA 3240
Query: 8539 XXTDVHDRRIXXXXXXXXXXXXLHVQERDDFASQLVRACSCLRNQEFVNYLMNILQQLVH 8718
DR + + C + + F+ + N +
Sbjct: 3241 ANASSGDRSSVSQAVLDNATFLAQTTANALMKNNAIPYCLMIM-ESFLPHWKNASASSID 3299
Query: 8719 VFKSRA-----ANVEARXXXXXXXXXAMLTVRRDLPAGNY---SPFFSDSYAKAHRADIF 8874
S A AN A + + G + PFF+ + K D+F
Sbjct: 3300 ELASPAIGASNANASANAASSSSGGAPSNVLLKPTMYGVFPDMQPFFARPFPKGSN-DVF 3358
Query: 8875 VDYHRLLLENVFRLVYTLVRPEKQEKMGEKEKVYRNASSKDLKLDGFQDVLCSYINNPHT 9054
Y ++L E RL Y +++ G N S + LC Y+ +
Sbjct: 3359 EMYSQVLTEMAVRLPYQILKLSS----GHPSSQEWNHSLCEY----MTSTLCEYMMYMQS 3410
Query: 9055 AFVRRYARRLFLHLCGSKTQYYSVRDSWQFSNEVKNLYKHVEK-----------SGGFEN 9201
+RR R+L L++CGSK +Y +RD +K + K E +
Sbjct: 3411 PVLRRQVRKLLLYICGSKEKYRQLRDLHSLDTHMKAVKKCCEAGYSQASSSPSLTSSHTT 3470
Query: 9202 NVSYERSVKIVKSLSTIAEVAVARPRNWQKYCLRHGDFLSFLLNGVFHFAEESVIQT-LK 9378
+SY+ V++ + E+A R NWQK+C R+ D LS LLN + EE V L+
Sbjct: 3471 ILSYDALVELTEHFRACQEIASIRTGNWQKFCGRNSDILSSLLNISTYQLEEGVSTIILQ 3530
Query: 9379 LLNLAFYQGKDVSSSVQKAEATEVVTGSNRSGSQSVDSKKKKKGEDGHDSGLEKLYVDME 9558
LL A + SS Q+++ + ++ SV K +K + +S + + E
Sbjct: 3531 LLQSAIC---NTSSQGQQSKPSSSGVTVDQQMKVSVVVKDRKDRDKSEES--DTMAAPSE 3585
Query: 9559 G----------VVDIFSANCGDLLRQFIDFFLLEWNSSSVRTEAKSVIYGLWHHGRHSFK 9708
V IF+ L +FI FLLE NS+S+R +A S++Y + + K
Sbjct: 3586 SKFDAAQCVALVAQIFNQVSPASLSKFIRSFLLETNSTSIRWQAHSLVYAFYENSSDLHK 3645
Query: 9709 ESLLAALLQKVRYLPAYGQNIVEYTELVSLLLDKAPENNSKQAINELVDRCLNPDVIRCF 9888
E+LL L LPAYG+ ++ +L+ L N++ I++L PD
Sbjct: 3646 ETLLQCLWSLWPLLPAYGKRTAQFVDLLGYLT-----LNTRSLIDKL------PDYTAQA 3694
Query: 9889 FETLHSQNELIANHPNSRIYSTLGNLVEFDGYYLESEPCVACSSPDVPYSKMKLESLKSE 10068
L QNEL++ HPN+ IY+ LG ++E +G+YLESEPC+ C++P+VP+S +KL ++K +
Sbjct: 3695 VSVLRQQNELLSKHPNAPIYTALGQVLELEGFYLESEPCLVCNNPEVPFSNIKLSTIKVD 3754
Query: 10069 TKFTDNRIIVKCTGSYTIQSVTMNVHDARKSKSVKVLNLYYNNRPVSDLSELKNNWSLWK 10248
+KFT IVK S+TI + + + D +++K V+ +N+YYNNR V + ELKN +W
Sbjct: 3755 SKFTTTTTIVKLVQSHTISKIVLRIADLKRAKMVRTINIYYNNRTVQAVVELKNRPLMWH 3814
Query: 10249 RAKSCHLSFNQTELKVEFPIPITACNFMIELDSFYENLQALSLEPLQCPRCSRPVTDKHG 10428
+A+ L QT++K++F +PITACN MIE FYE + S E LQCPRCS V G
Sbjct: 3815 KARKVTLQSGQTDVKIDFSLPITACNLMIEYADFYETVSG-SSESLQCPRCSAVVPANPG 3873
Query: 10429 ICSNCHENAYQCRQCRNINYENLDSFLCNECGYSKYGRFEFNFMAKPSFIFDNMENDEDM 10608
+C NC EN +QC +CR INY+ D FLC+ CG+ KY +F+++ + D +E+ ED
Sbjct: 3874 VCGNCGENVFQCHKCRAINYDEKDPFLCHSCGFCKYAKFDYSIYGRACCAVDPIESAEDR 3933
Query: 10609 KKGLAAIESESENAHKRYQQLLGFKKPLLKIVSSIGETEMDSQHKDT-VQQMMASLPGPS 10785
K + I + E A + Y+ L K+ L +V + E ++D +T V + G +
Sbjct: 3934 AKTVQTIHTSLEKADRSYKSLQNNKQILELLVQKVSEHKLDRTLDETLVGASVIGGAGGT 3993
Query: 10786 CKINRKIALLGVLYGEKCKAAFDSVSKSVQTLQGLRRVLMSYLHQK------------NS 10929
++N+ I LL Y + K F+ +SK +Q +Q R+ L++Y + ++
Sbjct: 3994 SQVNKVIQLLAQKYCVESKTTFEELSKIIQKVQACRKELVAYDRSQMDVPPTCGPGAMST 4053
Query: 10930 NF--SSGASRCVVSKTPNNCYGCATTFVTQCLEILQVLSKHPRSRKQLVAAGILSELFEN 11103
+F SSG S + T N CYGCA QCL +L+ ++ + R L + G++ EL N
Sbjct: 4054 SFASSSGTSTRTTAVTLNKCYGCALASTEQCLTLLRAMASNMACRVGLCSQGLVQELAIN 4113
Query: 11104 NIHQGPKTARAQARAALSTFSEGDLSAVNELNNLVQKKIMYCLEHHRSMDIALAT----- 11268
N+ +G + + R L + A L L+Q ++ L S + LAT
Sbjct: 4114 NLRRGTHQLQDEVRHLLCLLTRDLPDATGSLCQLLQDRVKMAL----SGTVPLATLDSAV 4169
Query: 11269 REEMLLLSEVCSLTDEFWESRLRLVFQLLFSSIKLGAKHPAISEHIILPCLKII-SVACT 11445
R EM LL + S D WE++LR V + LF A+ PA + +I PCL+I+ S+ C
Sbjct: 4170 RHEMALLEAMTSQDDSCWETKLRTVIE-LFLQASRDARGPATA--VIHPCLRIVQSLICP 4226
Query: 11446 PP----KPDTAEKEQTMGKSAPAVQE-------------KDENAAGVIKYXXXXXXXXXX 11574
PP T K+ + + ++Q+ ++ AG +
Sbjct: 4227 PPVLASTISTGSKQHSKEPTVSSLQDLCTVQPIEGITVSYEKWIAGDANHSFAAWKARMP 4286
Query: 11575 VSQKTRDIQLVSYLEWEKGASYLDFVRRQYKASQSI----RGASQKSR-THRSDFLALKY 11739
+ + S + A V SQ I R A + R T R+ +L KY
Sbjct: 4287 PAPTANTTGVTSRRTIGENAP-PPMVAAAAAPSQPIGTGFRSALEHRRATVRNAYLVEKY 4345
Query: 11740 TLRWKRRSSRTSKGGLQAFELGSWVTELILSACSQSIRSEMCTLISLLAAQSSPRRYRLI 11919
RW++R+ + +W+ ++ + S+ R C LI+ L ++++ R+ L+
Sbjct: 4346 AKRWRQRAMAKGVTSIPVELQAAWLQPILFNTNSRLGRQLACALITSL-SRTNERKRELL 4404
Query: 11920 NLLIGLLPATLAAGESSAEYFELLFKMIETQDALLFLTVRGCLTTICKLISQEVGNIESL 12099
+LL L +GE+SAE+ L + + +L ++G L+ + +L+++E+ I L
Sbjct: 4405 DLLTSFLRYVGDSGEASAEFLALYRMLADETPWRQYLALKGVLSLLVQLVTEEIEKIHCL 4464
Query: 12100 ER-SLQIDISQXXXXXXXXXXXXXXXXVPNIRSRFMRDNLLSHVLEALIVIRGLIVQKTK 12276
E +L D++Q P IR + + LL VL+ + +R LIVQ+T+
Sbjct: 4465 EETTLSTDLAQGYALRQLVELMALFLENPQIRKAY-KGKLLGPVLQGYLDLRKLIVQRTR 4523
Query: 12277 LINDCNRRXXXXXXXXXXESSENKRQFIRACVSGLQTHAEENKGRTCLFILEQLCNLICP 12456
LI+D + + E F+ C+ ++ + +T +F+ E+LC++I P
Sbjct: 4524 LIDDAQEKLLEMLEEMTTGTEEETAAFMAVCIDTVR-RTPTSDVKTPVFMFERLCSIIHP 4582
Query: 12457 SKPE-AVYMLILNKSHTQEEFIRGSMTKNPYSSAE--IGPLMRDVKNKICQQXXXXXXXX 12627
+ + + L L K QE++++G M NPY S E +GPLMRDVKNKIC
Sbjct: 4583 EENDVGEFFLTLEKDPQQEDYLQGRMLGNPYPSHEAGLGPLMRDVKNKICIDCELVALLD 4642
Query: 12628 XXXXXXXXVAGNIISLDLSIAQVYELVWKKSNQDCPPMTVTYRLQGLDGEATEPMIKELE 12807
V IISLDL + +VY+ +W + + M + YR++GL G+ATE I+ L
Sbjct: 4643 DDNGMELLVHNKIISLDLPVKEVYKKIWLQEGGERDSMRIVYRMRGLLGDATEEFIETLN 4702
Query: 12808 EDREESQDPEIEFAIAGAVREYGGLEILLDMIKSLQDDFKSNQEEMVAVLDLLNHCCKIR 12987
+E D E + +A + + GGL+++L+ I SLQ+ KS + + +L L K+
Sbjct: 4703 AKSQEEVDNEQLYRMANVLADCGGLKVMLERIGSLQNVSKS-RTLLQVLLKLFLLSVKV- 4760
Query: 12988 ENXXXXXXXXXXXXXXXXXXRAFSVDAMEPAEGI--LLIVESLTLEANESDSISAAQSAL 13161
R V I LL V L L++NESD A QSA+
Sbjct: 4761 -------------------SRCQEVLCQPELSAINTLLKVLQLCLQSNESD---AQQSAV 4798
Query: 13162 T----------VSNEETGTWEQAKKIVLMF-----LERLSHPSGLKKSNKQQRNTEMVAR 13296
T +S + T + + L F ++ L + + R
Sbjct: 4799 TEQLLEIMETILSKAASDTLDSFLQFSLTFGGPEYVQALLSCTNCSNVRCNPSVLRHLIR 4858
Query: 13297 ILPYLTYGEPAAMEALIEHFSPYLQNWSEFDQLQQRHEEDPKDDSIAQQAAKQRFTVENF 13476
+L L YG M L EHF L N+ FD A+++A++ F +E F
Sbjct: 4859 VLAALVYGNDIKMALLCEHFRSVL-NFDRFD---------------AERSAEEEFKMELF 4902
Query: 13477 VRVSESLKTSSCGERLKDIVLENGIIAVAVKHIKEIFAITGQTGFKSSKEWLLA-LKLPS 13653
++ ++ +S G LKD ++ GI+ A+ +IK T ++ + L + S
Sbjct: 4903 CVLTTGIEHNSIGGTLKDYIMSLGIVEKALGYIKSHAPCVKPTLLRTDSDELKEFISRAS 4962
Query: 13654 VPLILSMLRGLSMGHLPTQTCIDEGGILTLLHALEGVSGENDIGARAENLLDTLADKEGK 13833
+ IL L GL+ H TQ + + I+ ++H LE VS + +G+ AENLL+ L +
Sbjct: 4963 LKYILRFLTGLATKHEATQLAVAQ-DIIPIIHRLEQVSSDEHVGSLAENLLEALCTEPA- 5020
Query: 13834 GDGFLGEKVRALRDATKDXXXXXXXXXXXXXXQGLGMRQELSSDGGERIVVSQPILXXXX 14013
++V+ +RD T+ LGMR +++ G+ V ++ +
Sbjct: 5021 ----TAKRVQEVRDFTRAEKKRLAMATREKQLDALGMR---TNEKGQ--VTAKGSILSQI 5071
Query: 14014 XXXXXXXXLACMVCREGYKLRPSDLLGVYSYSKRVNLGVGNSGSARGECVYTTVSYFNII 14193
LAC +CREGY +P+ +LG+Y++SKR N+ + YTTV++FN++
Sbjct: 5072 EKLREETGLACFICREGYACQPNKVLGIYTFSKRANVEEFEM-KQKKTTGYTTVTHFNVV 5130
Query: 14194 HFQCHQEAKRADAALKNPKKEWEGAMLRNNESLCNSLFPVKGPSVPLAQYLRYVDQYWDN 14373
H CH A R L + EWE A L+N + CN L P+ GP V + + + ++
Sbjct: 5131 HVDCHMNAIR----LARSRDEWESASLQNANTRCNGLLPLWGPDVSESSFSSSMARHNTY 5186
Query: 14374 LNALGRADGSRLRLLTYDIVLMLARFATGASFSADCRGGGRDSNSRFLPFMFQMARHLLD 14553
+ + +D+ L+L RFA SF D GGG SN + ++ + L
Sbjct: 5187 MQECTQRCEITFASSMHDLKLLLWRFAQEKSFHEDAGGGGPQSNMHLVAYLLFYGLYTLL 5246
Query: 14554 QGGPVQRTNMXXXXXXXXXXXXXXXXXXXXXXXRPLTPGSQ-LSSTGTEETVQFMMVNSL 14730
R M P + L E +++ SL
Sbjct: 5247 SSRSYSREEMILTNFIGH------------------KPSERWLECAYEAEGPLYLLTMSL 5288
Query: 14731 LSESYESWLQHRRVFLQRGIYHTFMQHAHGRVASRAAEPTSSGGKTQDAETLTGDELLSI 14910
+ + W +H+ V LQR I +H + P K +I
Sbjct: 5289 ALHTPDLWSRHKLVHLQRLIVIAHARHVSPNSVCKFLAPADKHPKD-----------YTI 5337
Query: 14911 VKPMLVYTGMIE 14946
KP L++ G+++
Sbjct: 5338 YKPYLMFWGLVD 5349
Score = 294 bits (753), Expect = 3e-77
Identities = 232/840 (27%), Positives = 368/840 (43%), Gaps = 87/840 (10%)
Frame = +1
Query: 4678 DEEDA----NSERYLASKVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHRGH 4845
+EED+ + E L +K+CTF+ + +FM QHWY+C+TC + G CSVCA+VCH+ H
Sbjct: 1758 EEEDSTVEDSDEDSLGNKLCTFSITQKDFMNQHWYYCHTCKMVDGVGVCSVCARVCHKNH 1817
Query: 4846 RVVYSRSSRFFCDCGAGGVRGSSCQCLKPRKYNGNGSAPARGTNNFQSFLPLSEDADQL- 5022
+ Y++ FFCDCGA SCQ L R +G+G G+ + S L S DAD +
Sbjct: 1818 DISYAKYGNFFCDCGAK--EDGSCQALSRRSNSGHGEESILGSTSSASLLTRSNDADSVL 1875
Query: 5023 -----------------GESDSDVEEDGFGEENHVVLYIPKETQYKMSLLLEELGIEDRV 5151
G S S + E+ + I + ++ ++ + + +
Sbjct: 1876 LASSLLRRRHPSSPAHEGSSTSRTSQGKLSEKEQQLAKIIETSREALNNPSQWKTVIRCI 1935
Query: 5152 LELFSSLLPSITS------------KRDSGLSKEKQVNLGKDKVLSFDTDLLQLKKAYKS 5295
L F+SL+P+I + S L + + K VLS D ++ + +
Sbjct: 1936 LVFFNSLMPTIKEHCARYSPVGCYWRAKSALERLHRPE--KSYVLS-DEIMIATLGSQEG 1992
Query: 5296 GSLDLKIKADYTNSKDLKSLLANXXXXXXXXXXXXX------XXXXXGEGDKVAIFDVGQ 5457
++++ + +K LL+ E KV I +
Sbjct: 1993 AFENVRMNYSGEQGQTIKQLLSTYLVRRVALCCLASPHGKRQQLAISHEKGKVTILQLSA 2052
Query: 5458 LIGQATIAPINADKANVKPLSRNIVRFEIVHLSFNPVVENYLAVAGLEDCQILTLNHRGE 5637
L+ QA A K + L+ V ++ L+ NP E++LAV GL++C ILT G
Sbjct: 2053 LLKQADAAK---RKLTLTRLASAPVPCTVLSLASNPANEDFLAVCGLKECHILTFTSTGT 2109
Query: 5638 VIDRLAVELALQ-GAFIRRIDWVPGSQVQLMVVTNKFVKIYDLSQDSISPTQYFTLPNDM 5814
D + + L G FI+R W+P SQ ++ +VT FVKIYDL++DS SP YF +P+
Sbjct: 2110 ANDHIVLTPQLDTGNFIKRAIWLPSSQTKIALVTADFVKIYDLAEDSYSPQYYFLVPSGK 2169
Query: 5815 IVDATLFVASRGRVFLLVLSEQGNLYRFELS-----WGGNAGATPLKEIVQIMGKDVTGK 5979
I D T G ++L++S G +Y LS G T E+ + D G+
Sbjct: 2170 IRDCTFVYDQDGTYYMLIMSSLGYIYTQPLSDESLAKHGPFYVTSTLELDHPLITDDNGQ 2229
Query: 5980 ----GSSVYFSPTYRLLFISYHDGSSFMGRXXXXXXXXXXXXGMFEEESD---CKQRVAG 6138
G S+Y+S +LLF SY G +FM + S K
Sbjct: 2230 ILAGGVSIYYSHVLQLLFFSYAAGRNFMAPLTNVNDGVKCVINLVCNPSSKLLSKSTTQP 2289
Query: 6139 LHRWKELLAGSGLFICFSSVKSNAVLAVSLRGDGVCAQNLRHPTGSSSPMVGITAYKPLS 6318
L +W E+ GL +C N + ++ DG AQ ++ + M + +S
Sbjct: 2290 LCQWTEIPGHPGL-VCAMMQSLNNPVIFMIKPDGYMAQEIKAQNAKAKIMDMVAIRHSVS 2348
Query: 6319 -KDNVHCLVLHDDGSLQIY-----------SHVRSGVDTDSNF------------TAEKV 6426
+ ++L +DGSL+IY S V F +A K
Sbjct: 2349 GVEKTTLILLCEDGSLRIYAAHPENTGYWLSPEVQPVGQQQAFGWYGPGGSMYGKSARKS 2408
Query: 6427 KKLG----------SKILNNKTYAGAKPEFPLDFFERAFCITADVRLGSDAIRNGDSEGA 6576
KKLG S K G+ P FP+DFFE + G+D ++ +++
Sbjct: 2409 KKLGKQSAHGAGGASLSAGGKGATGSAPSFPIDFFEHCTLMNEVEYGGNDLLQIYNTQHL 2468
Query: 6577 KQSLASEDGFIESPSPVGFKISVSNPNPDIVMVGIRMHVGTTSASSIPSEVTIFQRSIKM 6756
K L S ++ S GF + VSN + ++V+ G+R+ +G+ + P VTI RS+
Sbjct: 2469 KHRLNSTGLYVTSTKANGFTLEVSNNDTNMVITGVRIQIGSQDVTKAPQRVTILGRSVTT 2528
Query: 6757 DEGMRCWYDIPFTVAESLLADEDVVISVGPTTSGTALPRIDSLEVYGRAKDEFGWKEKMD 6936
W+DIP T ESL +D+ + I G + + +DS+++YG+ KD FGW E+ +
Sbjct: 2529 VATRARWFDIPLTREESLQSDKKLSIHFGASVDAEQITILDSIKIYGKTKDVFGWPEETE 2588
Database: BlastDB/NCBI/blast/db/2003_02_17_02_00_1/nr
Posted date: Feb 17, 2003 10:02 AM
Number of letters in database: 429,188,541
Number of sequences in database: 1,339,046
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
length of database: 429,188,541
effective HSP length: 145
effective length of database: 235,026,871
effective search space used: 1172784086290
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)