BLASTX 1.4.13-Paracel [2002-12-12]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PTA.sd.15583.C1
(8899 letters)
Database: BlastDB/NCBI/blast/db/2003_02_17_02_00_1/nr
1,339,046 sequences; 429,188,541 total letters
Searching...................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_198861.1| putative protein; protein id: At5g40450.1 ... 4687 0.0
dbj|BAC42024.1| unknown protein [Arabidopsis thaliana] 293 3e-77
gb|AAF15293.3|AAF15293 erythrocyte membrane-associated gian... 286 4e-75
ref|NP_701352.1| antigen 332, putative [Plasmodium falcipar... 269 7e-70
ref|NP_725510.1| CG18255-PD [Drosophila melanogaster]|gi|21... 249 4e-64
>ref|NP_198861.1| putative protein; protein id: At5g40450.1 [Arabidopsis thaliana]
Length = 2910
Score = 4687 bits (12158), Expect = 0.0
Identities = 2476/2770 (89%), Positives = 2476/2770 (89%)
Frame = +2
Query: 341 REPQSLNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQEED 520
REPQSLNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQEED
Sbjct: 109 REPQSLNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQEED 168
Query: 521 IGNISKVLTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDSRTVETSVNGTEAEHN 700
IGNISKVLTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDSRTVETSVNGTEAEHN
Sbjct: 169 IGNISKVLTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDSRTVETSVNGTEAEHN 228
Query: 701 ATVSVEEISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNTEE 880
ATVSVEEISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNTEE
Sbjct: 229 ATVSVEEISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNTEE 288
Query: 881 TTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDKEKEEDIIQNIEEVQESPS 1060
TTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDKEKEEDIIQNIEEVQESPS
Sbjct: 289 TTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDKEKEEDIIQNIEEVQESPS 348
Query: 1061 VMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAKTAETF 1240
VMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAKTAETF
Sbjct: 349 VMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAKTAETF 408
Query: 1241 SVQEAEILKTNINESEAHSAIGGEEDGQETKENTEPSKDLKDDKEQEDSETVKTIISSDE 1420
SVQEAEILKTNINESEAHSAIGGEEDGQETKENTEPSKDLKDDKEQEDSETVKTIISSDE
Sbjct: 409 SVQEAEILKTNINESEAHSAIGGEEDGQETKENTEPSKDLKDDKEQEDSETVKTIISSDE 468
Query: 1421 VRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPEIETAVDGESVHEIETTE 1600
VRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPEIETAVDGESVHEIETTE
Sbjct: 469 VRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPEIETAVDGESVHEIETTE 528
Query: 1601 RVLLEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXXXXXXXXTSVHESESLKEN 1780
RVLLEA PSLNAIEKAET TSVHESESLKEN
Sbjct: 529 RVLLEAEKEEDKEEIKIDEEPSLNAIEKAETENVKIVIEEPEIVNNEETSVHESESLKEN 588
Query: 1781 AEPVEAVKNSDGTEQISREVTVDRAKEEDIAPKTEEIQERPSESKASLEPKEEVDHISNE 1960
AEPVEAVKNSDGTEQISREVTVDRAKEEDIAPKTEEIQERPSESKASLEPKEEVDHISNE
Sbjct: 589 AEPVEAVKNSDGTEQISREVTVDRAKEEDIAPKTEEIQERPSESKASLEPKEEVDHISNE 648
Query: 1961 TEEHEHVLERDVQQCETIESEAVETKEDTQPSLDLKEDKETEEAETFKTVFSSDEVRSSA 2140
TEEHEHVLERDVQQCETIESEAVETKEDTQPSLDLKEDKETEEAETFKTVFSSDEVRSSA
Sbjct: 649 TEEHEHVLERDVQQCETIESEAVETKEDTQPSLDLKEDKETEEAETFKTVFSSDEVRSSA 708
Query: 2141 VQEEQFGEHTEPCSSEIKDESHGKEESVEVKSQETVQDENTEDKHDVLKVPSTESEKYQG 2320
VQEEQFGEHTEPCSSEIKDESHGKEESVEVKSQETVQDENTEDKHDVLKVPSTESEKYQG
Sbjct: 709 VQEEQFGEHTEPCSSEIKDESHGKEESVEVKSQETVQDENTEDKHDVLKVPSTESEKYQG 768
Query: 2321 NEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELNDEKINVDQVDGTQIMEEPIGLDSNGA 2500
NEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELNDEKINVDQVDGTQIMEEPIGLDSNGA
Sbjct: 769 NEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELNDEKINVDQVDGTQIMEEPIGLDSNGA 828
Query: 2501 EAEQIDQNITNETEEILVAKPVSLLDVKSVEQMQKPKLESPSEVSEETSKTVDXXXXXXX 2680
EAEQIDQNITNETEEILVAKPVSLLDVKSVEQMQKPKLESPSEVSEETSKTVD
Sbjct: 829 EAEQIDQNITNETEEILVAKPVSLLDVKSVEQMQKPKLESPSEVSEETSKTVDEKIEEKP 888
Query: 2681 XXXVTLYQEGQVDGSYGLETKEETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTXXXXXXX 2860
VTLYQEGQVDGSYGLETKEETVSV RSVIDPTPLQKPT
Sbjct: 889 EEEVTLYQEGQVDGSYGLETKEETVSVPESIELEEQPQEERSVIDPTPLQKPTLESPSEV 948
Query: 2861 XXXXXKTVDEKIEEKTDSIELGEIAQEERSVTDLTPLQEESSQPNEQEKETKLEKHEPTN 3040
KTVDEKIEEKTDSIELGEIAQEERSVTDLTPLQEESSQPNEQEKETKLEKHEPTN
Sbjct: 949 LEESSKTVDEKIEEKTDSIELGEIAQEERSVTDLTPLQEESSQPNEQEKETKLEKHEPTN 1008
Query: 3041 EEVKSDEVIEVLSASPSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQTVXXXX 3220
EEVKSDEVIEVLSASPSKELEGETVV SLETVQTV
Sbjct: 1009 EEVKSDEVIEVLSASPSKELEGETVVEAENIENIKENEEEQAAEKIQKSLETVQTVESPS 1068
Query: 3221 XXXXXXXXQDHVTVAEEIVDEKAKEEVPMLQIKNEDDATKIHETRVEQARDIGPSLTEIC 3400
QDHVTVAEEIVDEKAKEEVPMLQIKNEDDATKIHETRVEQARDIGPSLTEIC
Sbjct: 1069 SLLFSSEEQDHVTVAEEIVDEKAKEEVPMLQIKNEDDATKIHETRVEQARDIGPSLTEIC 1128
Query: 3401 SINQNQPEEQVKEACSKEEQEKEISTNSENIVNETYALHSVXXXXXXXXXNGESLDDVET 3580
SINQNQPEEQVKEACSKEEQEKEISTNSENIVNETYALHSV NGESLDDVET
Sbjct: 1129 SINQNQPEEQVKEACSKEEQEKEISTNSENIVNETYALHSVEAAEEETATNGESLDDVET 1188
Query: 3581 TKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQDAKIVNNEETTAHESESLK 3760
TKS PRLDAI QDAKIVNNEETTAHESESLK
Sbjct: 1189 TKSVLLEVRKEEEEAEMKTDAEPRLDAIEKEELETVKTVVQDAKIVNNEETTAHESESLK 1248
Query: 3761 GDNHQEKNAEPVEATQNLDDAEQISREVTVDTEREADITEKIEKVQEGPTVIETPTIQGE 3940
GDNHQEKNAEPVEATQNLDDAEQISREVTVDTEREADITEKIEKVQEGPTVIETPTIQGE
Sbjct: 1249 GDNHQEKNAEPVEATQNLDDAEQISREVTVDTEREADITEKIEKVQEGPTVIETPTIQGE 1308
Query: 3941 DIESETSLELKEEVDQSSKDTEEHEHVLERDIPQCETLKAEAVDTSTVEEAAILKTLETN 4120
DIESETSLELKEEVDQSSKDTEEHEHVLERDIPQCETLKAEAVDTSTVEEAAILKTLETN
Sbjct: 1309 DIESETSLELKEEVDQSSKDTEEHEHVLERDIPQCETLKAEAVDTSTVEEAAILKTLETN 1368
Query: 4121 ISEPEAMHSETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDE 4300
ISEPEAMHSETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDE
Sbjct: 1369 ISEPEAMHSETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDE 1428
Query: 4301 SQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEE 4480
SQG TVQGESSEEKDVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEE
Sbjct: 1429 SQGSEESVEVKSKETVQGESSEEKDVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEE 1488
Query: 4481 IPSVVEGAGLDETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXXXXXXVTLHQEG 4660
IPSVVEGAGLDETTHNQTLLDVESVVKQSLDTPSEEETS VTLHQEG
Sbjct: 1489 IPSVVEGAGLDETTHNQTLLDVESVVKQSLDTPSEEETSKTIDEKIEDKPKEEVTLHQEG 1548
Query: 4661 REEGSYGLDTKDEAVSVLESRELGEQPQQEELCLANEQENETKLQEEQVDKHEPTKEEVS 4840
REEGSYGLDTKDEAVSVLESRELGEQPQQEELCLANEQENETKLQEEQVDKHEPTKEEVS
Sbjct: 1549 REEGSYGLDTKDEAVSVLESRELGEQPQQEELCLANEQENETKLQEEQVDKHEPTKEEVS 1608
Query: 4841 NDQQSPVEEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQVADKIQKSFETGEIVEAHS 5020
NDQQSPVEEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQVADKIQKSFETGEIVEAHS
Sbjct: 1609 NDQQSPVEEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQVADKIQKSFETGEIVEAHS 1668
Query: 5021 SLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAETTHLSLPSVDQKEDVDEIH 5200
SLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAETTHLSLPSVDQKEDVDEIH
Sbjct: 1669 SLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAETTHLSLPSVDQKEDVDEIH 1728
Query: 5201 IPSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSPMLSEKNDNETQTSKTSED 5380
IPSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSPMLSEKNDNETQTSKTSED
Sbjct: 1729 IPSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSPMLSEKNDNETQTSKTSED 1788
Query: 5381 VCMQQEESGTLEVPKPEESKEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSELVSE 5560
VCMQQEESGTLEVPKPEESKEDKSQ DQTLPIETSHTDNTLSSELVSE
Sbjct: 1789 VCMQQEESGTLEVPKPEESKEDKSQEISETIEEIEATSDQTLPIETSHTDNTLSSELVSE 1848
Query: 5561 QDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDADNTLSSQLVSETKEEHKLQAGE 5740
QDDQSP AHDVEATSERNLPVETSDADNTLSSQLVSETKEEHKLQAGE
Sbjct: 1849 QDDQSPKKVEEIHEEEPKEAHDVEATSERNLPVETSDADNTLSSQLVSETKEEHKLQAGE 1908
Query: 5741 ILPTEIIPRESSDEALVSMLASREDDKVALQEDNCADDVRETNDIQEERSISVETEESVG 5920
ILPTEIIPRESSDEALVSMLASREDDKVALQEDNCADDVRETNDIQEERSISVETEESVG
Sbjct: 1909 ILPTEIIPRESSDEALVSMLASREDDKVALQEDNCADDVRETNDIQEERSISVETEESVG 1968
Query: 5921 ETKPKEHEDEIRDAHVETPTAPIILEENDSETLIAEAKKGNEEINETERTVALDHEEEFV 6100
ETKPKEHEDEIRDAHVETPTAPIILEENDSETLIAEAKKGNEEINETERTVALDHEEEFV
Sbjct: 1969 ETKPKEHEDEIRDAHVETPTAPIILEENDSETLIAEAKKGNEEINETERTVALDHEEEFV 2028
Query: 6101 NHEAPKLEETKDEKSQEIPETAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTPKQVXX 6280
NHEAPKLEETKDEKSQEIPETAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTPKQV
Sbjct: 2029 NHEAPKLEETKDEKSQEIPETAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTPKQVEE 2088
Query: 6281 XXXXXXXXTHKVQAEDIFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERH 6460
THKVQAEDIFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERH
Sbjct: 2089 ILEEETKETHKVQAEDIFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERH 2148
Query: 6461 VSAETEEKVGETKPKESQAEGAEKSDDQVEDESTKKTDVEVAGLENDYPTEEAEHGDETY 6640
VSAETEEKVGETKPKESQAEGAEKSDDQVEDESTKKTDVEVAGLENDYPTEEAEHGDETY
Sbjct: 2149 VSAETEEKVGETKPKESQAEGAEKSDDQVEDESTKKTDVEVAGLENDYPTEEAEHGDETY 2208
Query: 6641 STLPVVGIXXXXXXXXXXXRAINDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDIL 6820
STLPVVGI RAINDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDIL
Sbjct: 2209 STLPVVGILTQLQTTLETERAINDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDIL 2268
Query: 6821 EAKRLHGDKSGEAEKIKEESGLAGKSLPIEEINLXXXXXXXXXXXXXTREIAQVLPREEI 7000
EAKRLHGDKSGEAEKIKEESGLAGKSLPIEEINL TREIAQVLPREEI
Sbjct: 2269 EAKRLHGDKSGEAEKIKEESGLAGKSLPIEEINLQEEHKEEVKVQEETREIAQVLPREEI 2328
Query: 7001 LISSSPLSAEEQEHVISDEKQEEREPQQDFNGSTSEKISLQVEHLKDFETSKKEQKDETH 7180
LISSSPLSAEEQEHVISDEKQEEREPQQDFNGSTSEKISLQVEHLKDFETSKKEQKDETH
Sbjct: 2329 LISSSPLSAEEQEHVISDEKQEEREPQQDFNGSTSEKISLQVEHLKDFETSKKEQKDETH 2388
Query: 7181 ETVXXXXXXXXXXXXXXXXXXXXXXSSEVKKDNKDARELEVGNDFVSRDGEKEEVPHNAL 7360
ETV SSEVKKDNKDARELEVGNDFVSRDGEKEEVPHNAL
Sbjct: 2389 ETVKEEDQIVDIKDKKKDDEEQEIVSSEVKKDNKDARELEVGNDFVSRDGEKEEVPHNAL 2448
Query: 7361 ENEEEMNEVVASEKQISDPVGVIKKASEAEHEDPVDDIKSNDDRDFPTEQAPKDQSDEVS 7540
ENEEEMNEVVASEKQISDPVGVIKKASEAEHEDPVDDIKSNDDRDFPTEQAPKDQSDEVS
Sbjct: 2449 ENEEEMNEVVASEKQISDPVGVIKKASEAEHEDPVDDIKSNDDRDFPTEQAPKDQSDEVS 2508
Query: 7541 ADETVPKEAIGEELKVPSSKVLDDIQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQV 7720
ADETVPKEAIGEELKVPSSKVLDDIQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQV
Sbjct: 2509 ADETVPKEAIGEELKVPSSKVLDDIQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQV 2568
Query: 7721 EETSFEFNKAQEDKKEETVDALITNVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQE 7900
EETSFEFNKAQEDKKEETVDALITNVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQE
Sbjct: 2569 EETSFEFNKAQEDKKEETVDALITNVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQE 2628
Query: 7901 DIGTYVKVQVPDDEIKGDGHDSVAAQKEETSSIEEKREVEHVKAEMEDAIKHEVSVEEKN 8080
DIGTYVKVQVPDDEIKGDGHDSVAAQKEETSSIEEKREVEHVKAEMEDAIKHEVSVEEKN
Sbjct: 2629 DIGTYVKVQVPDDEIKGDGHDSVAAQKEETSSIEEKREVEHVKAEMEDAIKHEVSVEEKN 2688
Query: 8081 NTSENIDHEAAKEIEQEEGKQTNIVXXXXXXXXXXXNQESFNNVKETDDAIDKTQPEIRD 8260
NTSENIDHEAAKEIEQEEGKQTNIV NQESFNNVKETDDAIDKTQPEIRD
Sbjct: 2689 NTSENIDHEAAKEIEQEEGKQTNIVKEEIREEEKEINQESFNNVKETDDAIDKTQPEIRD 2748
Query: 8261 IESLSSVSKTQDKPEPEYEVPNQQKREITNEVPSLENSXXXXXXXXXXXXXXNTKDLFSV 8440
IESLSSVSKTQDKPEPEYEVPNQQKREITNEVPSLENS NTKDLFSV
Sbjct: 2749 IESLSSVSKTQDKPEPEYEVPNQQKREITNEVPSLENSKIEEELQKKDEESENTKDLFSV 2808
Query: 8441 VKETEPTLKEPARKSLSDHIQXXXXXXXXXXXXXXXXXXXXXXSPDSIVMVEAKDTVSIV 8620
VKETEPTLKEPARKSLSDHIQ SPDSIVMVEAKDTVSIV
Sbjct: 2809 VKETEPTLKEPARKSLSDHIQKEPKTEEDENDDEDHEHKDDKTSPDSIVMVEAKDTVSIV 2868
Query: 8621 KTHKKSHGIL 8650
KTHKKSHGIL
Sbjct: 2869 KTHKKSHGIL 2878
Score = 231 bits (588), Expect = 2e-58
Identities = 503/2460 (20%), Positives = 909/2460 (36%), Gaps = 275/2460 (11%)
Frame = +2
Query: 344 EPQSLNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQEEDI 523
EP + + + I +VT++ KEED K EE I+E +E+K SLE +E++
Sbjct: 590 EPVEAVKNSDGTEQISREVTVDRAKEEDIAPKTEE-------IQERPSESKASLEPKEEV 642
Query: 524 GNISKVLTDTTPVKVDEYDIEKSLNSVCEEIPIKTD--------EVREETDSRTVETSVN 679
+IS + V E D+++ E + K D E +E ++ T +T +
Sbjct: 643 DHISNETEEHEHVL--ERDVQQCETIESEAVETKEDTQPSLDLKEDKETEEAETFKTVFS 700
Query: 680 GTEAEHNA-------------TVSVEEISRNGDNTVN----ETVSEDQTATDGEPLHDVE 808
E +A + +++ S + +V ETV ++ T E HDV
Sbjct: 701 SDEVRSSAVQEEQFGEHTEPCSSEIKDESHGKEESVEVKSQETVQDENT----EDKHDVL 756
Query: 809 TI-KREAEPFYKTVVEDAKIVNT---EETTAHESKIL-----KEDNHQEEYAESVEATK- 958
+ E+E + E + NT E++ S ++ +E N ++ + V+ T+
Sbjct: 757 KVPSTESEKYQGNEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELNDEKINVDQVDGTQI 816
Query: 959 -------NSDAAEQSSREVTVDKEKEEDII---------QNIEEVQ----ESPSVMESPT 1078
+S+ AE + + E EE ++ +++E++Q ESPS + T
Sbjct: 817 MEEPIGLDSNGAEAEQIDQNITNETEEILVAKPVSLLDVKSVEQMQKPKLESPSEVSEET 876
Query: 1079 IQGEDIESKASLDHEEEMDKITKDTEEQEHVL-VRDVPVPQSETLVTEAKTAETFSVQEA 1255
+ ++ K EEE+ + + + L ++ V E++ E + E SV +
Sbjct: 877 --SKTVDEKIEEKPEEEVTLYQEGQVDGSYGLETKEETVSVPESIELEEQPQEERSVIDP 934
Query: 1256 EILKTNINESEAHSAIGGEEDGQETKENTEPSKDLKDDKEQEDSETVKTIISSDEVRSSD 1435
L+ ES + + E E S +L + ++E S T T + + + ++
Sbjct: 935 TPLQKPTLESPSEVLEESSKTVDEKIEEKTDSIELGEIAQEERSVTDLTPLQEESSQPNE 994
Query: 1436 VQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPEIE--TAVDGESVHEIETTERVL 1609
+ E E EP + E+K D E IEV + E+E T V+ E++ I+ E
Sbjct: 995 QEKETKLEKHEPTNEEVKSD-----EVIEVLSASPSKELEGETVVEAENIENIKENEEEQ 1049
Query: 1610 LEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXXXXXXX------------XTSV 1753
PS E T +
Sbjct: 1050 AAEKIQKSLETVQTVESPSSLLFSSEEQDHVTVAEEIVDEKAKEEVPMLQIKNEDDATKI 1109
Query: 1754 HESE---------------SLKENAEPVEAVKNSDGTEQISREVTVD------------- 1849
HE+ S+ +N +P E VK + E+ +E++ +
Sbjct: 1110 HETRVEQARDIGPSLTEICSINQN-QPEEQVKEACSKEEQEKEISTNSENIVNETYALHS 1168
Query: 1850 -RAKEEDIAPKTEEIQERPSESKASLEPKEEVDHISNETE----------EHEHVLERDV 1996
A EE+ A E + + + LE ++E + +T+ E ++ V
Sbjct: 1169 VEAAEEETATNGESLDDVETTKSVLLEVRKEEEEAEMKTDAEPRLDAIEKEELETVKTVV 1228
Query: 1997 QQCETIESEAVETKEDTQPSLDLKEDKETEEAETFKTVFSSDEV-RSSAVQEEQFGEHTE 2173
Q + + +E E D ++K E E + + ++++ R V E+ + TE
Sbjct: 1229 QDAKIVNNEETTAHESESLKGDNHQEKNAEPVEATQNLDDAEQISREVTVDTEREADITE 1288
Query: 2174 PCSS-----------EIKDESHGKEESVEVKSQETVQDENTEDKHDVLK--VPSTESEKY 2314
I+ E E S+E+K + ++TE+ VL+ +P E+ K
Sbjct: 1289 KIEKVQEGPTVIETPTIQGEDIESETSLELKEEVDQSSKDTEEHEHVLERDIPQCETLKA 1348
Query: 2315 QGNEPETV-------LVSNTGSYEKSEKSPSDLVLNVDKEELNDEKINVDQVDGTQIMEE 2473
+ + TV + S ++ S + L L VDKE+ E + T I
Sbjct: 1349 EAVDTSTVEEAAILKTLETNISEPEAMHSETSLDLKVDKEQKEAETVK------TVIFSN 1402
Query: 2474 PIGLDSNGAEAEQIDQNITNETEEILVAKPVSLLDVKSVEQMQKPKLESPSEVSEETSKT 2653
+G ++ A+AE+ ++ + EI K S +SVE ++S V E+S+
Sbjct: 1403 EVG--TSDAQAEEFGEHTEPCSSEI---KDESQGSEESVE------VKSKETVQGESSEE 1451
Query: 2654 VDXXXXXXXXXXVTLYQEGQVDGSYGLET----KEETVSVXXXXXXXXXXXXXRSVIDPT 2821
D YQE + D S +T K E + ++++D
Sbjct: 1452 KDVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEEIPSVVEGAGLDETTHNQTLLDVE 1511
Query: 2822 PLQKPTXXXXXXXXXXXXKTVDEKIEEKT-DSIELGEIAQEERSVTDLT----------- 2965
+ K + KT+DEKIE+K + + L + +EE S T
Sbjct: 1512 SVVKQSLDTPSEEETS--KTIDEKIEDKPKEEVTLHQEGREEGSYGLDTKDEAVSVLESR 1569
Query: 2966 -----PLQEESSQPNEQEKETKLE-----KHEPTNEEVKSD----------EVIEVLSAS 3085
P QEE NEQE ETKL+ KHEPT EEV +D EVI+V SAS
Sbjct: 1570 ELGEQPQQEELCLANEQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSAS 1629
Query: 3086 PSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVA 3265
S+ E ETVV S ET + V ++H TV+
Sbjct: 1630 LSEGPEYETVVEAEKIGEEQVADKIQK------SFETGEIVEAHSSLPSSSEEKEHETVS 1683
Query: 3266 EEIVDEKAKEEVPMLQIKNED----DATKIHETRVEQARDIG----PSL----------- 3388
E+ DEK K+ P+ ++ + T + V+Q D+ PS+
Sbjct: 1684 EKTDDEKVKDAEPIGDMRERGLDIAETTHLSLPSVDQKEDVDEIHIPSVALPLDEQEKVT 1743
Query: 3389 ------TEICSINQNQPEEQVKEACS-----KEEQEKEISTNSENIVNETYALHSVXXXX 3535
T+ ++P+E V + S K + E + S SE++ + ++
Sbjct: 1744 STEKGETKSSEAEDDKPDEHVDSSTSPMLSEKNDNETQTSKTSEDVCMQQEESGTLEVPK 1803
Query: 3536 XXXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQDAKI 3715
+S + ET + + + + I
Sbjct: 1804 PEESKEDKSQEISETIEEIEATSDQTLPIETSHTDNTLSSELVSEQDDQSPKKVEE---I 1860
Query: 3716 VNNEETTAHESESLKGDNHQEKNAEPVEATQNLDDAEQISREVTVDTEREADI------- 3874
E AH+ E+ E+N PVE + D +S ++ +T+ E +
Sbjct: 1861 HEEEPKEAHDVEATS-----ERNL-PVETS---DADNTLSSQLVSETKEEHKLQAGEILP 1911
Query: 3875 TEKIEKVQEGPTVIETPTIQGEDIESETSLELKEEVDQSSKDTEEHEHVLERDIPQCETL 4054
TE I + ++ + +D + ++V +++ EE +E + ET
Sbjct: 1912 TEIIPRESSDEALVSMLASREDDKVALQEDNCADDVRETNDIQEERSISVETEESVGETK 1971
Query: 4055 KAEAVDT---STVEEAAILKTLETNISEPEAMHSETSLDLKVDKEQKEA-ETVKTVIFSN 4222
E D + VE LE N SE +L + K +E ET +TV +
Sbjct: 1972 PKEHEDEIRDAHVETPTAPIILEENDSE--------TLIAEAKKGNEEINETERTVALDH 2023
Query: 4223 EVGTSDAQAEEFGEHTEPCSSEIKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQSG 4402
E EEF H P E KDE T+ L + +
Sbjct: 2024 E--------EEFVNHEAPKLEETKDEKSQEIPETAKATETTID---------QTLPIGTS 2066
Query: 4403 ESEKYQENEPDISLVSKTENGDKFEEIPSVVEGAGLDETTHNQTLLDVESVVKQSLDTPS 4582
++++ SLVS DK ++ P VE L+E T + E + S +T
Sbjct: 2067 QADQTP------SLVS-----DKDDQTPKQVEEI-LEEETKETHKVQAEDIF--STETVP 2112
Query: 4583 EEETSXXXXXXXXXXXXXXVTLHQEGREEGSYGLDTKDEAVSVLESRELGEQPQQEELCL 4762
+E VT +EG Y +T++E E+ E + + +E
Sbjct: 2113 KESFIEAPVSMLASGEDEPVT-----PQEGDYAANTQEERHVSAETEEKVGETKPKESQA 2167
Query: 4763 ANEQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGPEYETVVEA 4942
++++ ++++E K + + ND + E +E + + +T +E
Sbjct: 2168 EGAEKSDDQVEDESTKKTDVEVAGLENDYPTEEAEHGDETYSTLPV-VGILTQLQTTLET 2226
Query: 4943 EKIGEEQVADKIQKSFETGEIVEAHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRE 5122
E+ + + ++ E P+ EEK+ + V E + + V D
Sbjct: 2227 ERAINDSASSEVSMIKE-----------PADQEEKKGDDVVESNEKDFVSD--------- 2266
Query: 5123 RGLDIAETTHLSLPSVDQKEDV-DEIHIPSVALPLDE---QEKVTSTEKGETKSSEAEDD 5290
I E L + E + +E + +LP++E QE+ K + ++ E
Sbjct: 2267 ----ILEAKRLHGDKSGEAEKIKEESGLAGKSLPIEEINLQEEHKEEVKVQEETREIAQV 2322
Query: 5291 KPDEHVDSSTSPMLSEKNDNETQTSK-------------TSEDVCMQQEESGTLEVPKPE 5431
P E + S+SP+ +E+ ++ K TSE + +Q E E K E
Sbjct: 2323 LPREEILISSSPLSAEEQEHVISDEKQEEREPQQDFNGSTSEKISLQVEHLKDFETSKKE 2382
Query: 5432 ESKEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSELVSEQDDQSPXXXXXXXXXXX 5611
+ E DQ + I+ D+ E+VS + +
Sbjct: 2383 QKDETHE---------TVKEEDQIVDIKDKKKDDE-EQEIVSSEVKKDNKDARELEVGND 2432
Query: 5612 XXAHDVEATSERNLPVETSDADNTL--SSQLVSE--------TKEEHKLQAGEI------ 5743
+ D E + +E + N + S + +S+ ++ EH+ +I
Sbjct: 2433 FVSRDGEKEEVPHNALENEEEMNEVVASEKQISDPVGVIKKASEAEHEDPVDDIKSNDDR 2492
Query: 5744 -LPTEIIPRESSDEALVSMLASREDDKVALQEDNCADDVRETNDIQEERSISVETEESVG 5920
PTE P++ SDE +E A+ E+ + +DIQE + T +
Sbjct: 2493 DFPTEQAPKDQSDEVSADETVPKE----AIGEELKVPSSKVLDDIQENSNTEAVTNFADR 2548
Query: 5921 ETKPKEHEDEIRDAHVETPTAPIILEENDSETLIAEAKKGNEEINETERTVALDHE--EE 6094
+ P ++ E+ +H +P +EE E A+ K E ++ V + + E+
Sbjct: 2549 DL-PVQNLSELIQSH----QSPNQVEETSFEFNKAQEDKKEETVDALITNVQVQDQPKED 2603
Query: 6095 FVNHEAPKLEETKDEKSQEIPETAKATETTIDQTLPIGTSQADQTPSLVSDKDD----QT 6262
F K ++ K ++ + + T + +P + D S+ + K++ +
Sbjct: 2604 FEAAAIEKEISEQEHKLNDLTDVQEDIGTYVKVQVPDDEIKGDGHDSVAAQKEETSSIEE 2663
Query: 6263 PKQVXXXXXXXXXXT-HKVQAEDIFST-ETVPKESF--IEAPVSMLASGEDEPVTPQEGD 6430
++V H+V E+ +T E + E+ IE + E + +E +
Sbjct: 2664 KREVEHVKAEMEDAIKHEVSVEEKNNTSENIDHEAAKEIEQEEGKQTNIVKEEIREEEKE 2723
Query: 6431 YAANTQEERHVSAETEEKVGETKPK-------ESQAEGAEKSDDQVEDESTKKTDV--EV 6583
QE + ET++ + +T+P+ S ++ +K + + E + +K ++ EV
Sbjct: 2724 I---NQESFNNVKETDDAIDKTQPEIRDIESLSSVSKTQDKPEPEYEVPNQQKREITNEV 2780
Query: 6584 AGLENDYPTEEAEHGDE-TYSTLPVVGIXXXXXXXXX--XXRAINDSASSEVSMIKEPAD 6754
LEN EE + DE + +T + + ++++D E ++ D
Sbjct: 2781 PSLENSKIEEELQKKDEESENTKDLFSVVKETEPTLKEPARKSLSDHIQKEPKTEEDEND 2840
Query: 6755 QEEKKG-------DDVVESNEKDFVSDILEAKRLHGDKSGEAEKIKE-----ESGLAGKS 6898
E+ + D +V KD VS + K+ HG SG K+K + L GKS
Sbjct: 2841 DEDHEHKDDKTSPDSIVMVEAKDTVSIVKTHKKSHGILSGVGSKVKHSISKVKKVLTGKS 2900
Score = 208 bits (529), Expect = 1e-51
Identities = 112/123 (91%), Positives = 114/123 (92%)
Frame = +1
Query: 16 METGVVTIQEPVSTKTDVGGVPAEVILEKSSMEVQKVNLSTVLDDEITSGADRGNNIITG 195
METGVVTIQEPVSTKTDVGGVPAEVILEKSSMEVQKVNLSTVLDDEITSGADRGNNIITG
Sbjct: 1 METGVVTIQEPVSTKTDVGGVPAEVILEKSSMEVQKVNLSTVLDDEITSGADRGNNIITG 60
Query: 196 EADVAEVVNGSGDKETEELKRENGEATKTISVLDDSKIVKDDQESIVVP*TSKPQRKKRR 375
EADVAEVVNGSGDKETEELKRENGEATKTISVLDDSKIVKDDQESIVV +PQ +
Sbjct: 61 EADVAEVVNGSGDKETEELKRENGEATKTISVLDDSKIVKDDQESIVV---REPQSLNEK 117
Query: 376 *ED 384
ED
Sbjct: 118 KED 120
>dbj|BAC42024.1| unknown protein [Arabidopsis thaliana]
Length = 237
Score = 293 bits (751), Expect = 3e-77
Identities = 158/205 (77%), Positives = 158/205 (77%)
Frame = +2
Query: 8036 MEDAIKHEVSVEEKNNTSENIDHEAAKEIEQEEGKQTNIVXXXXXXXXXXXNQESFNNVK 8215
MEDAIKHEVSVEEKNNTSENIDHEAAKEIEQEEGKQTNIV NQESFNNVK
Sbjct: 1 MEDAIKHEVSVEEKNNTSENIDHEAAKEIEQEEGKQTNIVKEEIREEEKEINQESFNNVK 60
Query: 8216 ETDDAIDKTQPEIRDIESLSSVSKTQDKPEPEYEVPNQQKREITNEVPSLENSXXXXXXX 8395
ETDDAIDKTQPEIRDIESLSSVSKTQDKPEPEYEVPNQQKREITNEVPSLENS
Sbjct: 61 ETDDAIDKTQPEIRDIESLSSVSKTQDKPEPEYEVPNQQKREITNEVPSLENSKIEEELQ 120
Query: 8396 XXXXXXXNTKDLFSVVKETEPTLKEPARKSLSDHIQXXXXXXXXXXXXXXXXXXXXXXSP 8575
NTKDLFSVVKETEPTLKEPARKSLSDHIQ SP
Sbjct: 121 KKDEESENTKDLFSVVKETEPTLKEPARKSLSDHIQKEPKTEEDENDDEDHEHKDDKTSP 180
Query: 8576 DSIVMVEAKDTVSIVKTHKKSHGIL 8650
DSIVMVEAKDTVSIVKTHKKSHGIL
Sbjct: 181 DSIVMVEAKDTVSIVKTHKKSHGIL 205
Score = 43.9 bits (102), Expect = 0.046
Identities = 58/257 (22%), Positives = 106/257 (40%), Gaps = 12/257 (4%)
Frame = +2
Query: 875 EETTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVD--KEKEEDIIQ-NIEEV 1045
E+ HE + +++N E EA K + E + + +E+E++I Q + V
Sbjct: 2 EDAIKHEVSVEEKNNTSENIDH--EAAKEIEQEEGKQTNIVKEEIREEEKEINQESFNNV 59
Query: 1046 QESPSVMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAK 1225
+E+ ++ + DIES +S+ T+D E E+ +VP Q + E
Sbjct: 60 KETDDAIDKTQPEIRDIESLSSVSK-------TQDKPEPEY----EVPNQQKREITNEVP 108
Query: 1226 TAETFSVQEAEILKTNINESEAHSAIGGEEDGQETKENTEPSKDLKDDKEQEDSETVKTI 1405
+ E ++E L+ ESE +D + TEP+ LK+ + S+ ++
Sbjct: 109 SLENSKIEEE--LQKKDEESE------NTKDLFSVVKETEPT--LKEPARKSLSDHIQKE 158
Query: 1406 ISSDEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPEIET--------- 1558
++E + D E KDD+ D + V+AK+T ++T
Sbjct: 159 PKTEEDENDDED------------HEHKDDKTSPDSIVMVEAKDTVSIVKTHKKSHGILS 206
Query: 1559 AVDGESVHEIETTERVL 1609
V + H I ++VL
Sbjct: 207 GVGSKVKHSISKVKKVL 223
Score = 37.7 bits (86), Expect = 3.3
Identities = 41/175 (23%), Positives = 75/175 (42%), Gaps = 24/175 (13%)
Frame = +2
Query: 6446 QEERHVSAETEEKVGETKPK-------ESQAEGAEKSDDQVEDESTKKTDV--EVAGLEN 6598
QE + ET++ + +T+P+ S ++ +K + + E + +K ++ EV LEN
Sbjct: 53 QESFNNVKETDDAIDKTQPEIRDIESLSSVSKTQDKPEPEYEVPNQQKREITNEVPSLEN 112
Query: 6599 DYPTEEAEHGDE-TYSTLPVVGIXXXXXXXXX--XXRAINDSASSEVSMIKEPADQEEKK 6769
EE + DE + +T + + ++++D E ++ D E+ +
Sbjct: 113 SKIEEELQKKDEESENTKDLFSVVKETEPTLKEPARKSLSDHIQKEPKTEEDENDDEDHE 172
Query: 6770 G-------DDVVESNEKDFVSDILEAKRLHGDKSGEAEKIKE-----ESGLAGKS 6898
D +V KD VS + K+ HG SG K+K + L GKS
Sbjct: 173 HKDDKTSPDSIVMVEAKDTVSIVKTHKKSHGILSGVGSKVKHSISKVKKVLTGKS 227
Score = 37.4 bits (85), Expect = 4.3
Identities = 45/196 (22%), Positives = 74/196 (36%), Gaps = 10/196 (5%)
Frame = +2
Query: 4769 EQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGPEYETVVEAEK 4948
+ E ++++E+ + KEE+ +++ +E N V + A PE +
Sbjct: 22 DHEAAKEIEQEEGKQTNIVKEEIREEEKEINQESFNNVKETDDAIDKTQPEIRDIESLSS 81
Query: 4949 IGEEQVADKIQKSFETG-----EIVEAHSSLPSSSEEKEHETVSEKTDDEK-----VKDA 5098
+ + Q DK + +E EI SL +S E+E + E++++ K VK+
Sbjct: 82 VSKTQ--DKPEPEYEVPNQQKREITNEVPSLENSKIEEELQKKDEESENTKDLFSVVKET 139
Query: 5099 EPIGDMRERGLDIAETTHLSLPSVDQKEDVDEIHIPSVALPLDEQEKVTSTEKGETKSSE 5278
EP + E SL QKE TE+ E
Sbjct: 140 EPT---------LKEPARKSLSDHIQKEP--------------------KTEEDEN---- 166
Query: 5279 AEDDKPDEHVDSSTSP 5326
DD+ EH D TSP
Sbjct: 167 --DDEDHEHKDDKTSP 180
Score = 36.2 bits (82), Expect = 9.6
Identities = 50/247 (20%), Positives = 94/247 (37%), Gaps = 4/247 (1%)
Frame = +2
Query: 4799 EQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQVADKI 4978
E KHE + EE +N ++ E + E+ Q EG + V E + E+++
Sbjct: 2 EDAIKHEVSVEEKNNTSENIDHEAAKEIEQ------EEGKQTNIVKEEIREEEKEIN--- 52
Query: 4979 QKSF----ETGEIVEAHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAET 5146
Q+SF ET + ++ + P + + +VS+ D + + P RE ++
Sbjct: 53 QESFNNVKETDDAID--KTQPEIRDIESLSSVSKTQDKPEPEYEVPNQQKREITNEVPSL 110
Query: 5147 THLSLPSVDQKEDVDEIHIPSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSP 5326
+ + QK+D + + + + E E T E S+ +P D +
Sbjct: 111 ENSKIEEELQKKDEESENTKDLFSVVKETEP-TLKEPARKSLSDHIQKEPKTEEDEN--- 166
Query: 5327 MLSEKNDNETQTSKTSEDVCMQQEESGTLEVPKPEESKEDKSQXXXXXXXXXXXXXDQTL 5506
+ D+E + KTS D + E T+ + K + + L
Sbjct: 167 ---DDEDHEHKDDKTSPDSIVMVEAKDTVSIVKTHKKSHGILSGVGSKVKHSISKVKKVL 223
Query: 5507 PIETSHT 5527
++SHT
Sbjct: 224 TGKSSHT 230
>gb|AAF15293.3|AAF15293 erythrocyte membrane-associated giant protein antigen 332 [Plasmodium
falciparum]
Length = 5458
Score = 286 bits (732), Expect = 4e-75
Identities = 591/2822 (20%), Positives = 1083/2822 (37%), Gaps = 149/2822 (5%)
Frame = +2
Query: 350 QSLNEKKE-DEKIILSDVTLENKK-EEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQEEDI 523
Q +NE+K +EK + ++ +E K E+ + + VS E PV E++ +E + EE
Sbjct: 159 QLINEEKPVEEKSVSEEIPVEEKSVSEEIPVEEKSVSEEIPVEEKNVSE---EIPVEEK- 214
Query: 524 GNISKVLTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDSRTVETSVNGTEAEHNA 703
N+S+ + +E +E+ +V EEIP++ + V EE VE N +E
Sbjct: 215 -NVSEEIPVEEKNVSEEIPVEEE--NVSEEIPVEEENVSEEIP---VEEE-NVSEEIPEG 267
Query: 704 TVSVEEISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNTEET 883
+++E++ + + TV E ++ D+ D P +++ET+ E VED + TE+
Sbjct: 268 GIAIEDVPVD-EETVTEEITVDEKIYDKLP-NEIETVNEEMP------VEDETL--TEQI 317
Query: 884 TAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDKEKEEDIIQNIEEVQE---- 1051
++ ++ +E ++ + E E +D + VT D +E+ I + ++E +E
Sbjct: 318 SSEHERVPEEIIEEKPFTEGEETESLTDEIVEEG-VVTDDIPEEQIITEKVQEEEEFVTG 376
Query: 1052 --SPSVMESPTIQGEDIESKASLDHEEEM-DKITKDTEEQEHVLVRDVPVPQS----ETL 1210
S + + +Q ED L E+ + +K+ ++ E +V+D V + E +
Sbjct: 377 ELSEEDIINEKVQEEDESVTEELPEEDIINEKVQEEEESAYQEIVQDGSVTKDVEYKELV 436
Query: 1211 VTEAKTAETFSVQEAEILKTNINESEAHSAIGGEEDGQETKENTEPSKDLKDDKEQEDSE 1390
+ + E F ++E INE E+ TKE + + ++ +ED
Sbjct: 437 NDDVRDKENFVIEEDPFKGQLINEGLP------VEEEFVTKELPVKEESVFEELTEEDQS 490
Query: 1391 TVKTIISSDEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPEIETAVDG 1570
K I V V EV + E + EI ++ +E +E + +G ET
Sbjct: 491 VTKEI----PVEEHSVFKEV--DEIESVTEEIVEEEGSVNEEVEEEVSVSGEVDETEYVT 544
Query: 1571 ESVHEIETTERVLLEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXXXXXXXXTS 1750
E V E E +L+ S +E+ S
Sbjct: 545 EEVEETELVNEEVLKEEGSASEKVVKEEGSASEKIVEEEG-------------------S 585
Query: 1751 VHESESLKENAEPVEAVKNSDGTEQISRE---VTVDRAKEEDIAPKTEEIQERPSES--- 1912
V E + +E E +V +E+I + VT + + EE + + I+E SE
Sbjct: 586 VTEETASEEIVEEEGSVTEESSSEEIVEDEGSVTEESSSEEIVEEEGSVIEESASEVIVE 645
Query: 1913 ---KASLEPKEEVDHISNETEEHEHVLERDVQQCETIESEAVETKEDTQPSLDLKEDKET 2083
AS E E+ ++ E E E + +VQ E++E E + Q +D E
Sbjct: 646 DEVSASKEIVEDEASVTEEVVEEEGAVSDEVQVTESVEDEIIN-----QGIVD--EVIVE 698
Query: 2084 EEAETFKTVFSSDE--VRSSAVQEE--QFGEHTEPCSSEIKDESHGKEESVEVKSQETVQ 2251
+EA + DE + AV+E + E T+P EI D+ E E K+
Sbjct: 699 QEASVTDEIVKEDESVIEEIAVEETVTEVVEETKPMDEEIVDQGSVVENVEEKKTM---- 754
Query: 2252 DENTEDKHDVLKVPSTESEKYQGNEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELNDEK 2431
DE D+ V V + E +K E + + GS + V++EEL E+
Sbjct: 755 DEEIVDQGSV--VENVEEKKTMDEE-----IGDQGSVAEK----------VEEEELVTEE 797
Query: 2432 -------INVDQVDGTQIMEEPIGLDSNGAEAEQIDQNITNETEEILVAKPVS------- 2569
IN D V I EE ++ + E+I+ +IT+E +E LV + +
Sbjct: 798 VIEREGSINEDIVKEASITEEVEQIEPVTGKVEKIE-SITDEIKEQLVPEDIKEEQLDFE 856
Query: 2570 ------------LLDVKSV-EQMQKPKLESPSEVSEETSKTVDXXXXXXXXXXVTLYQEG 2710
++V S+ E++++ + EV EE T + V + ++G
Sbjct: 857 EIVAQRASVNDEKVEVASITEEVEEEEKSVSEEVLEEEGSTTEKVVEEGSSTEVVVEEQG 916
Query: 2711 QV-------DGSYGLETKEETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXX 2869
V +GS E EE SV + +++
Sbjct: 917 SVSEEVLEEEGSTTEEVVEEQGSVTENLLEEESAS--QGIVEKEEFVDEEDSVKDQNVFE 974
Query: 2870 XXKTVDEKIEEKTDSIELGEIAQEERSVTDLTPLQEESSQPNEQEKETKLEKHEPTNEE- 3046
+V E++ E+ E G I ++ +T + EE NE+ +ET L E ++
Sbjct: 975 KEGSVTEQLVEE----EKGLINEDNEKEELITEMSEEIKSVNEEIEETDLSTEEIIKQQG 1030
Query: 3047 VKSDEVIEVLSASPSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQTVXXXXXX 3226
+ + E +E + K LE E+V + Q V
Sbjct: 1031 LATYEFVEEEKSLTDKLLEEESVTKEVGETEL-----------------STQEVVDEKVS 1073
Query: 3227 XXXXXXQDHVTVAEEIVDE-KAKEEV-------PMLQIKNEDDATKIHETRVEQARDIGP 3382
++ +V+EE+++E A EEV ++ K D + E +
Sbjct: 1074 VTEEVIEEEKSVSEEVLEEGSATEEVVEEGSCTEIVVEKGSDTEIVVEEGSATEIVVEEG 1133
Query: 3383 SLTEICSINQNQPEEQVKEACSKEEQEKEISTNSENIVNETYALHSVXXXXXXXXXNGES 3562
S TE+ + EE ++E S E+ E +S+N+ + +V ES
Sbjct: 1134 SATEVVVEEGSVSEEMLEEEGSATEEVVEEGLSSDNVQKSKGVIENVGEIYSVKTAKDES 1193
Query: 3563 LDD-VETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQDAKIVNNEETTA 3739
+++ + KS +++ + ++ TTA
Sbjct: 1194 MNEKIPLEKSSFVDDESFKGQGPTDNVSVEDVNSEDIINEHTPLEETKIEELPTEYITTA 1253
Query: 3740 H-----ESESLKGDNHQEKNAEPVEA---TQNLDDAEQISRE-VTVDTEREADITEKIEK 3892
E+E+ +++ N E +A + + + + RE VT D +E + +++E+
Sbjct: 1254 DIHTRGETETKYNLIYEKINEEVEKAKFQEEKITENIPVERESVTEDIVQEPSLAQEVEQ 1313
Query: 3893 VQEGPTVIETPTIQGEDIESETSLELKEEVDQSSKDTEEHEHVLERDIPQCETLKAEAVD 4072
+ IE + E I E S+ + V++ DTEE VLE D E++
Sbjct: 1314 KESDTNEIEETKLANEKIIPEVSV-TENVVEKEGLDTEE---VLEED---------ESIT 1360
Query: 4073 TSTVEEAAILKTLETNISEPEAMHSETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQAE 4252
VEE E + E E+S + V++E+ +E + V ++ +E
Sbjct: 1361 EEIVEE-------EVSACEEIVEEEESSSEEIVEEEESSSEEI--------VEEEESSSE 1405
Query: 4253 EFGEHTEPCSSEIKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQSGESEKYQENEP 4432
E E E S EI +E + T E E++ ++ + E E
Sbjct: 1406 EIVEEEESSSEEIVEEEESSSEEIIEEVSST---EEVLEEEGSVTEEIVEEEVSTTEEVK 1462
Query: 4433 DISLVSK---TENGDKFEEI----PSVVEGAGLDETTHNQTLLDVESVVKQSLDTPS--- 4582
DI VS+ E G EE SV+E E++ + L DV S V++ +
Sbjct: 1463 DIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEKVLEDVGSNVEEIVQEEGPVA 1522
Query: 4583 ----EEETSXXXXXXXXXXXXXXVTLHQEGREEGSYGLDTKDEAVSVLESRELGEQPQQE 4750
EE S + + G ++ + ++E + E+ +E
Sbjct: 1523 QEIVHEEVSTTEKHDEVDRSTTEEIVEKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEE 1582
Query: 4751 ELCLANEQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGPEYET 4930
E L NE + EE V K EEV + S EEI + V EG E
Sbjct: 1583 EK-LINEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSVTEE 1641
Query: 4931 VVE----AEKIGEEQVADKIQKSFETGEIVEAHSSLPSSSEEKEHETVSEKTDDEKVKDA 5098
+V+ AE++ EE++ + +E G + E + E+E + E E +++
Sbjct: 1642 IVDYGSFAEEVKEEELVTEEAVQYE-GSVTE---EIKEEESITENEAIEESAFAEIIEEK 1697
Query: 5099 EPIGD--MRERGLDIAETTHLSLPSVDQKEDVDEIHIPSVALPLDEQEKVTSTEKGETKS 5272
P D ++E GLD E + + + E+ ++ V EK E+ T+
Sbjct: 1698 GPNNDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIVGEERSVTEKPVEVERSATED 1757
Query: 5273 SEAE----DDKPDEHVDSSTSPMLSEKNDNETQTSKTSEDVCMQQEESGTLEVPKPEESK 5440
E +K H S+T +L E E + S D + +EE EV + E S
Sbjct: 1758 LVEEGASVTEKVSVHEGSTTEQILDESVAEEIVEEEVSVDDKIIEEEVSVDEVVEEEGSV 1817
Query: 5441 EDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSELVSEQDDQSPXXXXXXXXXXXXXA 5620
++ ++ L E S ++ L E V++
Sbjct: 1818 IEE------IVEEEESVPEEILEEELSGSEEVLEDEWVTD----------AFMGQEGSVI 1861
Query: 5621 HDVEATSERNLPVETSDADNTLSSQLVSETK------EEHKLQAGEILPTE-IIPRESSD 5779
++E E D + +++ ++V + EE + E+L E + E +
Sbjct: 1862 EEIE---------EIVDGEGSITEEIVEDGSANEKIVEEEPSRVEEVLGKEGFVIEEIIE 1912
Query: 5780 EALVSMLASREDDKVALQEDNCADDVRETNDIQEERSIS---VETEESVGETKPKEHEDE 5950
E S++ ED K ++ + + E +++EE SIS VE EESV E ++ E
Sbjct: 1913 EG--SVIEQVEDTKTVSEKSEESSAIEEVKEVKEEESISEKIVEKEESVTEEIVRQEEST 1970
Query: 5951 IRDAHVETPTAPIILEENDSET-LIAEAKKGNEEIN---ETERTVALDHEEEFVNHEAPK 6118
+ +E+ DS T + E + N E+ E + + + +HE+E V+ A
Sbjct: 1971 TEKIVKDVSPTEDFVEQTDSVTEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSVNAQV 2030
Query: 6119 LEETKDEKSQEIPETAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTPKQVXXXXXXXX 6298
E K ++EI + TE +++ + T D+T S+ + ++ V
Sbjct: 2031 TCE-KKSVTKEIVDEVSRTEEIVEENGSV-TEGVDETGSVTEEIIEEA--TVTEEVVEDG 2086
Query: 6299 XXTHKVQAEDIFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAETE 6478
T +V + E V S E V S +E + +EG +EE VS E +
Sbjct: 2087 SVTEEVVEDGSVIQEVVEDGSVTEEIVQENGSVTEE-IVEEEGSVNEEVEEEVSVSGEVD 2145
Query: 6479 EKVGETKPKESQAEGAEKSDDQVEDESTKKTDVEVAGLENDYPTEE---------AEHGD 6631
E E +E + EG+ + E+ S + VE G + EE E G
Sbjct: 2146 ET--EYVTEEVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGS 2203
Query: 6632 ETYSTLPVVGIXXXXXXXXXXXRAINDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVS 6811
+ G + + E S+++E ++E +++VE E V
Sbjct: 2204 VVEEIVEEEG-SVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVE-EEGSVVE 2261
Query: 6812 DILE-----AKRLHGDKSGEAEKIKEESGLAGKSLPIEEINLXXXXXXXXXXXXXTREIA 6976
+I+E + + ++ E+I EE G + + EE ++ +
Sbjct: 2262 EIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEG------SVV 2315
Query: 6977 QVLPREEILISSSPLSAEEQEHVISDEKQ---EEREPQQDFNGSTSEKISLQVEHLKDFE 7147
+ + EE + + E + DE + +E Q F E++S+ E ++D
Sbjct: 2316 EEIVEEEGSVVEEIVEEEGSVSEVVDETELVNDEIVEQAPFTEEVEEQVSVNDEIIEDAS 2375
Query: 7148 TSKKEQKDETHETVXXXXXXXXXXXXXXXXXXXXXXSSEVKKDNKDAREL-----EVGND 7312
++ ++ E+ + E+ +D E+ V +
Sbjct: 2376 VAEAVEESESITESVSQEEETEKGFVIEKVEETGAVTEEIVQDGLITEEILEESESVNGE 2435
Query: 7313 FVSRDGEKEEVPHNALENEEEMNEVVASEKQISDPVGVIKKASEAEHEDPVDDIKSNDDR 7492
++++ + EE+ EE + + ++ ++I + G + K E E E +++ D
Sbjct: 2436 IINKESDAEEILETEFLTEEVVGQAGSTSEEIVEEEGSVTKEVE-EKESVTEELV---DE 2491
Query: 7493 DFPTEQAPKDQSDEVSADETVPKE--AIGEELKVPSSKVLDDIQENSNTEAVTNFADRDL 7666
TE+ DE S E V ++ +I +E+ S + I++ +N E V +
Sbjct: 2492 GSVTEEL----VDEGSVTEEVVEQGGSIAQEIVEEESATEEIIRDETNVEEVL-----EK 2542
Query: 7667 PVQNLSELIQSHQSPNQVEETSFEFNKAQEDKKEETVDALITNVQVQDQPKEDFEAAAIE 7846
E++Q N +F Q EE V+ I+ +++ KE EA+AIE
Sbjct: 2543 EGSATEEIVQDGSGTN-------DFVGKQGSVIEEVVEEEIST--TEEKLKE--EASAIE 2591
Query: 7847 KEISEQ---EHKLNDLTDVQEDIGTYVKVQVPDDEIKGDGHDSVAAQKEETSSIEEKREV 8017
+ + E+ E L + + +G + V ++ + G+G + +EE S EE
Sbjct: 2592 EFVEEESIREDVLEESLVTENVVGQ--QESVTEEIVDGEGSFTEDIVEEEESVTEE---- 2645
Query: 8018 EHVKAEMEDAIKHEVSVEEKNNTSENIDHEAA--KEIEQEEGKQTNIVXXXXXXXXXXXN 8191
E+++ E+ +E+ T E ++ E + +EI ++EG T V +
Sbjct: 2646 ---IVVDEESVTKEIVEDEELVTEEIVEDEGSFTEEIVEDEGSFTEEVIEERSLIEEVED 2702
Query: 8192 QESFNNVKE---TDDAIDKTQPEIRDIESLSSVSKTQDKPEPEYEVPNQQKREITNEVPS 8362
E+ +E + ID+ + +E SV++ ++ E E +Q+ + E +
Sbjct: 2703 TETVAEKEEGSVIKEIIDEKSLTEKIVEEEKSVTEEVEEKESVKEEVEEQRLVVEEEGSA 2762
Query: 8363 LE 8368
E
Sbjct: 2763 TE 2764
Score = 265 bits (676), Expect = 1e-68
Identities = 589/2831 (20%), Positives = 1087/2831 (37%), Gaps = 171/2831 (6%)
Frame = +2
Query: 341 REPQSLNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQEED 520
+E E E+++ I ++ E + + EE S E+ ++EE+++ ++ +E+EE
Sbjct: 1344 KEGLDTEEVLEEDESITEEIVEEEVSACEEIVEEEESSSEE-IVEEEESSSEEIVEEEES 1402
Query: 521 IGNISKVLTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDSRTVETSVNGTEAEHN 700
+++ ++ E + E S + EE+ T+EV EE S T E E E +
Sbjct: 1403 SSEEIVEEEESSSEEIVEEE-ESSSEEIIEEVS-STEEVLEEEGSVTEEI----VEEEVS 1456
Query: 701 ATVSVEEISRNGDNTVNET--VSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNT 874
T V++I + + E +E+ G + ++ E E + V+ED N
Sbjct: 1457 TTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIV----ETESSTEKVLEDVG-SNV 1511
Query: 875 EETTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDK--EKEEDIIQNIEEVQ 1048
EE E + +E H+E V T+ D ++S+ E V+K E+II +EEV
Sbjct: 1512 EEIVQEEGPVAQEIVHEE-----VSTTEKHDEVDRSTTEEIVEKVGSVSEEII--VEEVS 1564
Query: 1049 ESPSVMESPTIQGEDIESKASLDHEEEMDKIT-----KDTEEQEHVL------------- 1174
S ++E ++ E +E + ++ E + +T K+ + E VL
Sbjct: 1565 ASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEILEK 1624
Query: 1175 ---VRDVPVPQ------------------SETLVTEAKTAETFSVQEAEILKTNINESEA 1291
V ++ P+ E LVTE SV E + +I E+EA
Sbjct: 1625 ESIVEEIVGPEGSVTEEIVDYGSFAEEVKEEELVTEEAVQYEGSVTEEIKEEESITENEA 1684
Query: 1292 HSAIGGEEDGQETKENTEPSKDLKDDKEQEDSETVKTIIS-SDEVRSSD--VQAEVFGEH 1462
E E E P+ D +E D+E + +S +DEV + V ++ GE
Sbjct: 1685 IE----ESAFAEIIEEKGPNNDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIVGEE 1740
Query: 1463 TEPCSSEIKDDRHGRDESIEVKAKETGPEIETAVDGESVHEIETTERVLLEAXXXXXXXX 1642
++ +R ++ +E A T + SVHE TTE++L E+
Sbjct: 1741 RSVTEKPVEVERSATEDLVEEGASVT--------EKVSVHEGSTTEQILDESVAEEIVEE 1792
Query: 1643 XXXXXXPSL--------------NAIEKAETXXXXXXXXXXXXXXXXXTSVHESESLKEN 1780
+ + IE+ V E E + +
Sbjct: 1793 EVSVDDKIIEEEVSVDEVVEEEGSVIEEIVEEEESVPEEILEEELSGSEEVLEDEWVTDA 1852
Query: 1781 --------AEPVEAVKNSDG--TEQISRE-------VTVDRAKEEDIAPKTEEIQERPSE 1909
E +E + + +G TE+I + V + ++ E++ K + E E
Sbjct: 1853 FMGQEGSVIEEIEEIVDGEGSITEEIVEDGSANEKIVEEEPSRVEEVLGKEGFVIEEIIE 1912
Query: 1910 SKASLEPKEEVDHISNETEEHEHVLE-RDVQQCETIESEAVETKEDTQPSLDLKEDKETE 2086
+ +E E+ +S ++EE + E ++V++ E+I + VE +E + +E+ TE
Sbjct: 1913 EGSVIEQVEDTKTVSEKSEESSAIEEVKEVKEEESISEKIVEKEESVTEEIVRQEESTTE 1972
Query: 2087 E-----AETFKTVFSSDEVRSSAVQEEQFGEHTEPCSSEIKDESHGKE---ESVEVKSQE 2242
+ + T V +D V +++E G +TE + ES E E V V +Q
Sbjct: 1973 KIVKDVSPTEDFVEQTDSVTEKVIEQE--GSNTEVAEDVEEKESASDEHEQEDVSVNAQV 2030
Query: 2243 TVQDENTEDKHDVLKVPSTESEKYQGNEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELN 2422
T + ++ K V +V TE E + N T V TGS + + V +E +
Sbjct: 2031 TCEKKSV-TKEIVDEVSRTE-EIVEENGSVTEGVDETGSVTEEIIEEA----TVTEEVVE 2084
Query: 2423 DEKINVDQVDGTQIMEEPIGLDSNGAEAEQIDQNITNETEEILVAKPVSLLDVKSVEQMQ 2602
D + + V+ +++E + +G+ E+I Q + TEEI
Sbjct: 2085 DGSVTEEVVEDGSVIQEVV---EDGSVTEEIVQENGSVTEEI------------------ 2123
Query: 2603 KPKLESPSEVSEETSKTVDXXXXXXXXXXVTLYQEGQVDGSYGLETKEETVSVXXXXXXX 2782
+E V+EE + V VT +E + +GS E EE SV
Sbjct: 2124 ---VEEEGSVNEEVEEEVSVSGEVDETEYVT--EEVEEEGSVVEEIVEEEGSVVEEIVEE 2178
Query: 2783 XXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKIEEKTDSIELGEIAQEERSVTDL 2962
SV++ ++ V+E +EE+ +E EI +EE SV +
Sbjct: 2179 EG-----SVVEEIVEEE-------------GSVVEEIVEEEGSVVE--EIVEEEGSVVEE 2218
Query: 2963 TPLQEESSQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSASPSKELEGETVVXXXXXXXX 3142
+E S E+E + + E +E++E + + +E E V
Sbjct: 2219 IVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSV-------- 2270
Query: 3143 XXXXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVAEEIVDEKAK--EEVPMLQI 3316
V+ + ++ +V EEIV+E+ EE+ +
Sbjct: 2271 ------------------VEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEG 2312
Query: 3317 KNEDDATKIHETRVEQARDIGPSLTEICSINQNQPEEQVKEACSKEEQEKEISTNSENIV 3496
++ + + VE+ + S++E+ + +E V++A EE E+++S N E I
Sbjct: 2313 SVVEEIVEEEGSVVEEIVEEEGSVSEVVDETELVNDEIVEQAPFTEEVEEQVSVNDEIIE 2372
Query: 3497 NETYALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXX 3676
+ SV ES+ E T+
Sbjct: 2373 DA-----SVAEAVEESESITESVSQEEETEKGFVIEK-------------------VEET 2408
Query: 3677 XXXXXXXXQDAKIVNNEETTAHESESLKGD-NHQEKNAEPVEATQNLDD---------AE 3826
QD I E ESES+ G+ ++E +AE + T+ L + +E
Sbjct: 2409 GAVTEEIVQDGLIT---EEILEESESVNGEIINKESDAEEILETEFLTEEVVGQAGSTSE 2465
Query: 3827 QISRE---VTVDTEREADITEKI--------EKVQEGPTVIETPTIQGEDIESETSLELK 3973
+I E VT + E + +TE++ E V EG +V E QG I E +E +
Sbjct: 2466 EIVEEEGSVTKEVEEKESVTEELVDEGSVTEELVDEG-SVTEEVVEQGGSIAQEI-VEEE 2523
Query: 3974 EEVDQSSKDTEEHEHVLERDIPQCETLKAEAVDTSTV---EEAAILKTLETNISEPEAMH 4144
++ +D E VLE++ E + + T+ + + I + +E IS E
Sbjct: 2524 SATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFVGKQGSVIEEVVEEEISTTEEKL 2583
Query: 4145 SE--TSLDLKVDKEQ-KEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDESQGXX 4315
E ++++ V++E +E ++++ N VG ++ EE + + +I +E +
Sbjct: 2584 KEEASAIEEFVEEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIVEEEE--- 2640
Query: 4316 XXXXXXXXXTVQGESSEEKDVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEEIPSVV 4495
V E S K++ ++ + +E+ E+E + + G EE+ +
Sbjct: 2641 ----SVTEEIVVDEESVTKEI--VEDEELVTEEIVEDEGSFTEEIVEDEGSFTEEV--IE 2692
Query: 4496 EGAGLDETTHNQTLLDVE--SVVKQSLDTPSEEETSXXXXXXXXXXXXXXVTLHQEGREE 4669
E + ++E +T+ + E SV+K+ +D S E ++ +E E+
Sbjct: 2693 ERSLIEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEEEKSVTEEVEEKESVKEEVEEQ 2752
Query: 4670 GSYGLDTKDEAVSVLESRELGEQPQQEELCLANEQENETKLQEEQVDKHEPTKEEVSNDQ 4849
+ ++E R L + +++ + E + +E V++ EEV +D+
Sbjct: 2753 RLVVEEEGSATEGIVEDR-LATEGIVDDILVTEEIVEDGLATDEFVEQQGSIIEEVLDDE 2811
Query: 4850 QSPVEEI------SNEVIQVSSASLSEGPEYETVVEAEKIGEEQVADKIQKSFETGEIVE 5011
S EEI NE I + + E E V +E+I E V +++ K E++
Sbjct: 2812 GSVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPV--SEEIVEGSVTEEMIKEGLENEVIL 2869
Query: 5012 AHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAETTHLSLPSVDQKEDVD 5191
S+ + EKE E ++ E + + R D+ E S + ++ V+
Sbjct: 2870 DEDSITEEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEGSASEEIIQEESQVE 2929
Query: 5192 E-IHIPSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSPMLSEKNDNETQTSK 5368
E + SV + E++++ + E E E+ + + S + + ++ + +
Sbjct: 2930 EVVEEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGSVNEE 2989
Query: 5369 TSEDVCMQQEESGTLEVPKPEESKEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSE 5548
E+V EE +V EE E++S ++ + IE + L +E
Sbjct: 2990 IIEEVGSITEEMVEQDVSDNEEIVEERS---------VIEEAEENVWIEKEVEEEGLDNE 3040
Query: 5549 LVSEQDD------QSPXXXXXXXXXXXXXAHDV---------EATSERNLPVETSDADNT 5683
V +++D + DV E E E ++ D
Sbjct: 3041 EVIDEEDSVSEQAEEEVYINEEILKESSDVEDVKVENELMNEEVNEETQSVAENNEEDKE 3100
Query: 5684 LSSQLVSETKEEHKLQAGEILPT--EIIPRESSDEALVSMLASREDDKVALQEDNCADDV 5857
L + +V ET+ + + +P E+ ES E +V DD V Q + V
Sbjct: 3101 LDNYVVEETESVTEEVVVDEVPNSKEVQEIESIIEEIVED-GLTTDDLVGQQGSVIEEVV 3159
Query: 5858 RE----TNDIQEERSISVETEESVGETKPKEHEDEIRDAHVETPTAPIILEENDSETLIA 6025
E + I EE SI+ E E+ T ED + + E+ T I++E + +E ++
Sbjct: 3160 EEVGSDSEGIVEEASITEEVEKKESVT-----EDILVE---ESVTGDILVEGSVTEEVVG 3211
Query: 6026 EAKKGNEEINETERTVALDHEEEFVNHEAPKLEETKDEKSQEIPETAKATETTIDQTLPI 6205
E K +EEI E +VA +E V +AP E EI E TE +++ P+
Sbjct: 3212 EEKLVSEEIVTEEGSVA----QEIVEEDAPATE--------EIDEIESVTEEVVEEEGPV 3259
Query: 6206 GTSQADQTPSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETVPKESFIEAPVSM 6385
+ Q V+++ Q +V ++ E++ +++ + +
Sbjct: 3260 -DEEIVQEEGSVTEEIIQGESKVEEVVEEQGSENEEIFVEEVSASQEIVQNE-------- 3310
Query: 6386 LASGEDEPVTPQEGDYAANTQEERHVSAETEEKVGETKPKESQAEGAEKS--DDQVEDES 6559
SG +E + + + +QE + TE+ + E KP + E+S + +++ES
Sbjct: 3311 --SGTEEIL-----EKVSASQEIVQDGSVTEQIIEEQKPVTEEVVNEEESITHEIIQEES 3363
Query: 6560 TKKTDVEVAGLENDYPTEEAEHGDETYSTLPVVGIXXXXXXXXXXXRAINDSASSEVSMI 6739
+ V+ + + +E ++ + E +
Sbjct: 3364 HVEKVVQQGSVAEEVVENPVSVTEEIVE----------------KEGSVTEDIGQEGYVA 3407
Query: 6740 KEPADQEEKKGDDVV--ESNEKDFVSDILEAKRLHGDKSGEAEKIKEESGLAGKSLPIEE 6913
+E ++EE ++++ ES ++FV + + + + ++ ++E +KEE+ + + L E
Sbjct: 3408 EEIVEEEEFDNEEILEEESVAEEFVEEGFDNEEIFVEQISDSEIVKEENSVNEEVLEEE- 3466
Query: 6914 INLXXXXXXXXXXXXXTREIAQV--LPREEILISSSPLSAE--EQEHVISDEKQEE---- 7069
T EI + EEIL + E E+E ++E EE
Sbjct: 3467 -------------GSYTEEILEEEGSYTEEILEEEGSFTEEILEEEGSYNEEILEEEGSY 3513
Query: 7070 REPQQDFNGSTSEKISLQVEHLKDFETSKKEQKDETHETVXXXXXXXXXXXXXXXXXXXX 7249
E + GS +E+I + D+ + +E E
Sbjct: 3514 NEEILEEEGSFTEEILEEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQGSIIEEVLEEE 3573
Query: 7250 XXSSEVKKDNK-DARELEVGNDFVSRDGEKEEVPHNALENEEEMNEVVASEKQISDPVGV 7426
+E +N+ A E E F E E V N LE E +NEV E D
Sbjct: 3574 GLDTEKVFENEGSATEFEETESFTEVVEETESVNENILE-ETSINEVQKIESITEDIKEQ 3632
Query: 7427 IKKASEAEHEDPVDDIKSN--DDRDFPTEQAPKDQSDEVSADETVPKEAIGEELKVPSSK 7600
+ E + ++IK D + EQ S+E+ ++ VP+E E+L K
Sbjct: 3633 LVPEEIKEEQLDSEEIKEEQLDSEEIKEEQL---DSEEIKEEQLVPEEIKEEQLDSEEIK 3689
Query: 7601 VLDDIQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQVEETSFEFNKAQEDKKEETVD 7780
+ E E + N E+ + +++E + E+ KEE +D
Sbjct: 3690 EEQLVPEEIKEEQL-----------NSEEIKEEQLDSEEIKEEQLD----SEEIKEEQLD 3734
Query: 7781 ALITNVQ---VQDQPKEDFEAAAIEKEISEQEHKLND--LTDVQEDIGTYVKVQVPDDEI 7945
+ Q V ++ E E ++ +EI EQE +N+ L +V+E +K ++ +
Sbjct: 3735 SEEIKEQKGSVNEEVVE--EEGSVTEEIKEQEESVNEEVLEEVEET--ESIKEEIVEG-- 3788
Query: 7946 KGDGHDSVAAQKEETSSIEEKREVEHVKAEMEDAIKHEVSVEEKNNTSENIDHEAAKEIE 8125
G + ++ +T + E+ ++ K ++ EV EE + T E ++ + E
Sbjct: 3789 -GIATQEIIEEESDTKEVVEEEVIDSEKLVDAGSVTGEVMPEEVSVTDEVVEEGSTTEEV 3847
Query: 8126 QEEGKQTN--IVXXXXXXXXXXXNQESFNN--VKETDDAIDKTQPEIRDIESL--SSVSK 8287
EE K N +V Q S V+E AI+K E E + VS
Sbjct: 3848 LEEQKSVNEEVVEDGLTIDDFVGLQGSTTEEVVEEDGSAIEKILEEETATEEIVEKQVSV 3907
Query: 8288 TQDKPEPEYEV 8320
T+D E E V
Sbjct: 3908 TEDIVEKEGSV 3918
Score = 256 bits (653), Expect = 6e-66
Identities = 639/3045 (20%), Positives = 1159/3045 (37%), Gaps = 364/3045 (11%)
Frame = +2
Query: 314 KMIKNLLSFREPQSLNEKKEDEKIILSDVTLENKK-EEDTTGKPEEVSVEKPVIEEDQTE 490
K + + E E +EK + ++ +E K E+ + E VS E PV EE+ +E
Sbjct: 192 KSVSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEENVSEEIPVEEENVSE 251
Query: 491 ----AKHSLEQE--------EDIGNISKVLTDTTPVKVDEYD-IEKSLNSVCEEIPIKTD 631
+ ++ +E ED+ + +T+ V YD + + +V EE+P++ +
Sbjct: 252 EIPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEEMPVEDE 311
Query: 632 EVR-----------------------EETDSRTVETSVNGT-----EAEHNATVSVEEIS 727
+ EET+S T E G E T V+E
Sbjct: 312 TLTEQISSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQEEE 371
Query: 728 R------NGDNTVNETV-SEDQTATDGEPLHDV--ETIKREAEPFYKTVVEDAKIVN--- 871
+ ++ +NE V ED++ T+ P D+ E ++ E E Y+ +V+D +
Sbjct: 372 EFVTGELSEEDIINEKVQEEDESVTEELPEEDIINEKVQEEEESAYQEIVQDGSVTKDVE 431
Query: 872 -----TEETTAHESKILKEDNH-----------QEEYAESVEATKNSDAAEQSSRE-VTV 1000
++ E+ +++ED +EE+ K E+ + E +V
Sbjct: 432 YKELVNDDVRDKENFVIEEDPFKGQLINEGLPVEEEFVTKELPVKEESVFEELTEEDQSV 491
Query: 1001 DKE---KEEDIIQNIEEVQE-SPSVMESPTIQGEDIESKASLDHE-EEMDKITKDTEEQE 1165
KE +E + + ++E++ + ++E E++E + S+ E +E + +T++ EE E
Sbjct: 492 TKEIPVEEHSVFKEVDEIESVTEEIVEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEETE 551
Query: 1166 HVLVRDVPVPQ----SETLVTEAKTAETFSVQEAEILKTNINESEAHSAIGGEEDGQETK 1333
LV + + + SE +V E +A V+E + ++ E A I EE+G T+
Sbjct: 552 --LVNEEVLKEEGSASEKVVKEEGSASEKIVEE----EGSVTEETASEEI-VEEEGSVTE 604
Query: 1334 ENTEPSKDLKDDKEQEDSETVKTIISSDEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDE 1513
E++ + ++D+ + + + I+ + + +EV E S EI +D E
Sbjct: 605 ESSS-EEIVEDEGSVTEESSSEEIVEEEGSVIEESASEVIVEDEVSASKEIVEDEASVTE 663
Query: 1514 SIEVKAKETGPEIET--AVDGESVHEIETTERVLLEAXXXXXXXXXXXXXXPSLNAIEKA 1687
+ + E++ +V+ E +++ E ++ + A+E+
Sbjct: 664 EVVEEEGAVSDEVQVTESVEDEIINQGIVDEVIVEQEASVTDEIVKEDESVIEEIAVEET 723
Query: 1688 ETXXXXXXXXXXXXXXXXXTSVHESESLKENAEPVEAVKNSDGTEQISREVTVDR--AKE 1861
T + V E K E E V E + + T+D +
Sbjct: 724 VTEVVEETKPMDEEIVDQGSVVENVEEKKTMDE--EIVDQGSVVENVEEKKTMDEEIGDQ 781
Query: 1862 EDIAPKTEE---IQERPSESKASLEPKEEVDHISNETEEHEHVLERDVQQCETIESEAVE 2032
+A K EE + E E + S+ E++ ++ TEE E + E + E IES E
Sbjct: 782 GSVAEKVEEEELVTEEVIEREGSI--NEDIVKEASITEEVEQI-EPVTGKVEKIESITDE 838
Query: 2033 TKEDTQPSLDLKEDK-ETEEAETFKTVFSSDEVRSSAVQEEQFGEHTEPCSSEIKDESHG 2209
KE P D+KE++ + EE + + ++V +++ EE E + S E+ +E
Sbjct: 839 IKEQLVPE-DIKEEQLDFEEIVAQRASVNDEKVEVASITEE-VEEEEKSVSEEVLEEEGS 896
Query: 2210 KEESV--EVKSQETVQDENTEDKHDVLKVPSTESEKY---QGNEPETVLVSNTGSYEKSE 2374
E V E S E V +E +VL+ + +E+ QG+ E +L E
Sbjct: 897 TTEKVVEEGSSTEVVVEEQGSVSEEVLEEEGSTTEEVVEEQGSVTENLL---------EE 947
Query: 2375 KSPSDLVLNVDKEELNDEK-----INVDQVDGT---QIMEEPIGLDSNGAEAEQIDQNIT 2530
+S S + V+KEE DE+ NV + +G+ Q++EE GL + E E++ IT
Sbjct: 948 ESASQGI--VEKEEFVDEEDSVKDQNVFEKEGSVTEQLVEEEKGLINEDNEKEEL---IT 1002
Query: 2531 NETEEI-LVAKPVSLLDVKSVEQMQKPKLESPSEVSEETSKTVDXXXXXXXXXXVTLYQE 2707
+EEI V + + D+ + E +++ L + V EE S T V
Sbjct: 1003 EMSEEIKSVNEEIEETDLSTEEIIKQQGLATYEFVEEEKSLTDKLLEEESVTKEV----- 1057
Query: 2708 GQVDGSYGLETKEETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVD 2887
G+ + S E +E VSV + L++ + + V
Sbjct: 1058 GETELS-TQEVVDEKVSV------TEEVIEEEKSVSEEVLEEGSATEEVVEEGSCTEIVV 1110
Query: 2888 EKIEEKTDSIELG---EIAQEERSVTDLTPLQEESSQPNEQEKETKLEKHEPTNEEVKSD 3058
EK + +E G EI EE S T++ + EE S E +E E E + SD
Sbjct: 1111 EKGSDTEIVVEEGSATEIVVEEGSATEV--VVEEGSVSEEMLEEEGSATEEVVEEGLSSD 1168
Query: 3059 EVI----------EVLSASPSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQTV 3208
V E+ S +K+ + S+E V +
Sbjct: 1169 NVQKSKGVIENVGEIYSVKTAKDESMNEKIPLEKSSFVDDESFKGQGPTDNVSVEDVNS- 1227
Query: 3209 XXXXXXXXXXXXQDHVTVAEEIVDEKAKEEVPMLQIKNEDDA--------TKIHETRVEQ 3364
+H + E ++E E + I + KI+E VE+
Sbjct: 1228 --------EDIINEHTPLEETKIEELPTEYITTADIHTRGETETKYNLIYEKINE-EVEK 1278
Query: 3365 ARDIGPSLTEICSINQNQPEEQV--KEACSKEEQEKEISTN--------SENIVNETYAL 3514
A+ +TE + + E + + + ++E ++KE TN +E I+ E
Sbjct: 1279 AKFQEEKITENIPVERESVTEDIVQEPSLAQEVEQKESDTNEIEETKLANEKIIPEVSVT 1338
Query: 3515 HSVXXXXXXXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXX 3694
+V E LD E + +
Sbjct: 1339 ENV--------VEKEGLDTEEVLEEDESITEEIVEEEVSACEEIVEEEESSSEEIVEEEE 1390
Query: 3695 XXQDAKIVNNEETTA----HESESLKGDNHQEKNAEPVEATQNLDDAEQISRE---VTVD 3853
+ +IV EE+++ E ES + +E+ + E + + E++ E VT +
Sbjct: 1391 SSSE-EIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIIEEVSSTEEVLEEEGSVTEE 1449
Query: 3854 -TEREADITEKIEKV---------QEGPTVIETPTIQG----EDIESETSLE-LKEEVDQ 3988
E E TE+++ + +EG E QG E +E+E+S E + E+V
Sbjct: 1450 IVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEKVLEDVGS 1509
Query: 3989 SSKDTEEHEHVLERDIPQCE---TLKAEAVDTSTVEE------AAILKTLETNISEPEAM 4141
+ ++ + E + ++I E T K + VD ST EE + + + +S E +
Sbjct: 1510 NVEEIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEEIVEKVGSVSEEIIVEEVSASEEI 1569
Query: 4142 HSETSLDLKVDKEQK------EAETVKTVIFSNEVGTSDAQAEEFGEHTEPC-------- 4279
E S+ +V +E+K E E+V I EV ++ + G E
Sbjct: 1570 VEEGSVTEEVVEEEKLINEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEILEKESIVE 1629
Query: 4280 -------------------SSEIKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQSG 4402
+ E+K+E T + + E N +S
Sbjct: 1630 EIVGPEGSVTEEIVDYGSFAEEVKEEELVTEEAVQYEGSVTEEIKEEESITENEAIEESA 1689
Query: 4403 ESEKYQENEPDISLVSKTENGDKFEEIPSVVEGAGLDETTHNQTLLDVESVVKQS--LDT 4576
+E +E P+ + K E D EEI V E + DE + L++ + V ++ +
Sbjct: 1690 FAEIIEEKGPNNDEIVKEEGLDT-EEI--VNEVSVTDEVIEEEKLVNEQIVGEERSVTEK 1746
Query: 4577 PSE-EETSXXXXXXXXXXXXXXVTLHQEGREEGSYGLDTKDEAVS---VLESRELGEQPQ 4744
P E E ++ V++H EGS DE+V+ V E + ++
Sbjct: 1747 PVEVERSATEDLVEEGASVTEKVSVH-----EGSTTEQILDESVAEEIVEEEVSVDDKII 1801
Query: 4745 QEELCLANEQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEI-------------SNEVI 4885
+EE+ + E E + EE V++ E EE+ ++ S EE+ VI
Sbjct: 1802 EEEVSVDEVVEEEGSVIEEIVEEEESVPEEILEEELSGSEEVLEDEWVTDAFMGQEGSVI 1861
Query: 4886 Q-----------VSSASLSEGPEYETVVEAEKIGEEQVADK----IQKSFETGEIV---- 5008
+ ++ + +G E +VE E E+V K I++ E G ++
Sbjct: 1862 EEIEEIVDGEGSITEEIVEDGSANEKIVEEEPSRVEEVLGKEGFVIEEIIEEGSVIEQVE 1921
Query: 5009 ---------EAHSSLPSSSEEKEHETVSEK------------------TDDEKVKDAEPI 5107
E S++ E KE E++SEK T ++ VKD P
Sbjct: 1922 DTKTVSEKSEESSAIEEVKEVKEEESISEKIVEKEESVTEEIVRQEESTTEKIVKDVSPT 1981
Query: 5108 GDMRERGLDIAE-TTHLSLPSVDQKEDVDEIHIPSVALPLDEQE--------KVTSTEKG 5260
D E+ + E + + EDV+E S DE E +VT +K
Sbjct: 1982 EDFVEQTDSVTEKVIEQEGSNTEVAEDVEEKESAS-----DEHEQEDVSVNAQVTCEKKS 2036
Query: 5261 ETKSSEAEDDKPDEHVDSS---------TSPMLSEKNDNETQTSKTSEDVCMQQE--ESG 5407
TK E + +E V+ + T + E + T T + ED + +E E G
Sbjct: 2037 VTKEIVDEVSRTEEIVEENGSVTEGVDETGSVTEEIIEEATVTEEVVEDGSVTEEVVEDG 2096
Query: 5408 TL--EVPKPEESKED---KSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSELVSEQDDQ 5572
++ EV + E+ ++ ++ + E S + +E V+E+ ++
Sbjct: 2097 SVIQEVVEDGSVTEEIVQENGSVTEEIVEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEE 2156
Query: 5573 SPXXXXXXXXXXXXXAHDVEATSERNLPVETSDADNTLSSQLVSE---TKEEHKLQAGEI 5743
++ E ++ E + + ++ ++V E EE + G +
Sbjct: 2157 EGSVVEEIVEEEGSVVEEI-VEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSV 2215
Query: 5744 LPTEIIPRESSDEALVSMLASRED---DKVALQEDNCADDVRETND------IQEERSIS 5896
+ EI+ E S +V + E +++ +E + +++ E ++EE S+
Sbjct: 2216 V-EEIVEEEGS---VVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVV 2271
Query: 5897 VETEESVGETKPK--EHEDEIRDAHVETPTAPI--ILEENDS--ETLIAEAKKGNEEINE 6058
E E G + E E + + VE + + I+EE S E ++ E EEI E
Sbjct: 2272 EEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVE 2331
Query: 6059 TERTVA-LDHEEEFVNHE----APKLEETKDEKS--QEIPETAKATETTID-QTLPIGTS 6214
E +V+ + E E VN E AP EE +++ S EI E A E + +++ S
Sbjct: 2332 EEGSVSEVVDETELVNDEIVEQAPFTEEVEEQVSVNDEIIEDASVAEAVEESESITESVS 2391
Query: 6215 QADQT-PSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETVPKES---------F 6364
Q ++T V +K ++T ++ + + E + KES F
Sbjct: 2392 QEEETEKGFVIEKVEETGAVTEEIVQDGLITEEILEESESVNGEIINKESDAEEILETEF 2451
Query: 6365 IEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAE-------TEEKVGETKPKESQAE- 6520
+ V A E + +EG +E+ V+ E TEE V E E E
Sbjct: 2452 LTEEVVGQAGSTSEEIVEEEGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVTEEVVEQ 2511
Query: 6521 GAEKSDDQVEDEST------KKTDVEVAGLENDYPTEE-AEHGDETYSTLPVVGIXXXXX 6679
G + + VE+ES +T+VE + TEE + G T + G
Sbjct: 2512 GGSIAQEIVEEESATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFVGKQG------ 2565
Query: 6680 XXXXXXRAINDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDILEAKRLHGDKSGEA 6859
I + E+S +E +E ++ VE E+ D+LE + + G+
Sbjct: 2566 ------SVIEEVVEEEISTTEEKLKEEASAIEEFVE--EESIREDVLEESLVTENVVGQQ 2617
Query: 6860 EKIKEE--SGLAGKSLPIEEINLXXXXXXXXXXXXXTREIAQVLPREEILISSSPLSAEE 7033
E + EE G + I E T+EI + +E L++
Sbjct: 2618 ESVTEEIVDGEGSFTEDIVEEEESVTEEIVVDEESVTKEIVE----DEELVT-------- 2665
Query: 7034 QEHVISDEKQEEREPQQDFNGSTSEKISLQ--VEHLKDFETSKKEQKDETHETVXXXXXX 7207
E ++ DE E +D T E I + +E ++D ET ++++ + +
Sbjct: 2666 -EEIVEDEGSFTEEIVEDEGSFTEEVIEERSLIEEVEDTETVAEKEEGSVIKEIIDEKSL 2724
Query: 7208 XXXXXXXXXXXXXXXXSSEVKKDNKDARELEVGNDFVSRDGEKEEVPHNALENEEEMNEV 7387
E K+ + + L V + + +G + + L E ++++
Sbjct: 2725 TEKIVEEEKSVTEEVEEKESVKEEVEEQRLVVEEEGSATEG----IVEDRLATEGIVDDI 2780
Query: 7388 VASEKQISDPVGVIKKASEAEH--EDPVDDIKSNDDRDFPTEQAPKDQSDE----VSADE 7549
+ +E+ + D + + + E+ +DD S + E +P ++ E + D+
Sbjct: 2781 LVTEEIVEDGLATDEFVEQQGSIIEEVLDDEGSVTEEIVEEEGSPNEEIVEGVSVIEEDD 2840
Query: 7550 TVPKEAIGEELKVPSSKVLDDIQENSNTEAVTNFADRDLPVQNLSELIQS------HQSP 7711
+ E + EE+ V S + I+E E + D D + E S +
Sbjct: 2841 NI--EPVSEEI-VEGSVTEEMIKEGLENEVI---LDEDSITEEALEKEGSVSEEIVEEMG 2894
Query: 7712 NQVEETSFEFNKAQEDKKEETVDALITNVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTD 7891
+ EE E ED EE A +Q + Q +E E ++ EI E++ D +
Sbjct: 2895 SLTEEIVDEERSTSEDMIEEG-SASEEIIQEESQVEEVVEEVSVIDEIVEEDEL--DTKE 2951
Query: 7892 VQEDIGTYVKVQVPDDEIKGDGHDSVAAQKEETSSIEE-KREVEHVKAEM--EDAIKHEV 8062
V E+I + V E +G + + +++E S EE EV + EM +D +E
Sbjct: 2952 VVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGSVNEEIIEEVGSITEEMVEQDVSDNEE 3011
Query: 8063 SVEEKNNTSENIDHEAAKEIEQEEGKQTNIVXXXXXXXXXXXNQESFNN---VKETDDAI 8233
VEE++ E ++ ++ +EEG V +E + N +KE+ D
Sbjct: 3012 IVEERSVIEEAEENVWIEKEVEEEGLDNEEVIDEEDSVSEQAEEEVYINEEILKESSDVE 3071
Query: 8234 D-KTQPEIRDIESLSSVSKTQDKPEPEYEVPN---QQKREITNEV 8356
D K + E+ + E + E + E+ N ++ +T EV
Sbjct: 3072 DVKVENELMNEEVNEETQSVAENNEEDKELDNYVVEETESVTEEV 3116
Score = 248 bits (634), Expect = 9e-64
Identities = 583/2903 (20%), Positives = 1091/2903 (37%), Gaps = 226/2903 (7%)
Frame = +2
Query: 344 EPQSLNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQE--- 514
E S+NE+ E+E + +V ++ E T EE SV + ++EE+ + + +E+E
Sbjct: 2126 EEGSVNEEVEEEVSVSGEV---DETEYVTEEVEEEGSVVEEIVEEEGSVVEEIVEEEGSV 2182
Query: 515 -----EDIGNISKVLTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDSRTVETSVN 679
E+ G++ + + + V+E I + SV EEI + V EE E SV
Sbjct: 2183 VEEIVEEEGSVVEEIVEEEGSVVEE--IVEEEGSVVEEIVEEEGSVVEEIVEE--EGSVV 2238
Query: 680 GTEAEHNATVSVEEISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDA 859
E +V VEEI + V E V E+ + + E ++ E + V E+
Sbjct: 2239 EEIVEEEGSV-VEEIVEEEGSVVEEIVEEEGSVVE-------EIVEEEGSVVEEIVEEEG 2290
Query: 860 KIVNTEETTAHESKILKEDNHQE-EYAESVEATKNSDAAEQSSREVTVDKEKEEDIIQNI 1036
+V EE E +++E +E E + + S E E +V + +E + N
Sbjct: 2291 SVV--EEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVVEEIVEEEGSVSEVVDETELVND 2348
Query: 1037 EEVQESP---SVMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSET 1207
E V+++P V E ++ E IE + + EE + IT+ ++E V ET
Sbjct: 2349 EIVEQAPFTEEVEEQVSVNDEIIEDASVAEAVEESESITESVSQEEETEKGFVIEKVEET 2408
Query: 1208 -----------LVTEAKTAETFSVQ---------EAEILKTNINESEAHSAIGG------ 1309
L+TE E+ SV EIL+T E G
Sbjct: 2409 GAVTEEIVQDGLITEEILEESESVNGEIINKESDAEEILETEFLTEEVVGQAGSTSEEIV 2468
Query: 1310 EEDGQETKENTEPSKDLKDDKEQEDSETVKTIISSDEVRSSDVQAEVFGEHTEPCSSEIK 1489
EE+G TKE ++KE E V ++E+ E E + EI
Sbjct: 2469 EEEGSVTKE--------VEEKESVTEELVDEGSVTEELVDEGSVTEEVVEQGGSIAQEIV 2520
Query: 1490 DDRHGRDESI-------EVKAKETGPEIETAVDGESVHEIETTERVLLEAXXXXXXXXXX 1648
++ +E I EV KE E DG ++ + ++E
Sbjct: 2521 EEESATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFVGKQGSVIEEVVEEEISTTE 2580
Query: 1649 XXXXPSLNAIEKAETXXXXXXXXXXXXXXXXXTSVHESESLKENA-EPVEAVKNSDGTEQ 1825
+AIE+ E ES++E+ E +N G ++
Sbjct: 2581 EKLKEEASAIEEFV----------------------EEESIREDVLEESLVTENVVGQQE 2618
Query: 1826 ISREVTVDRAKE--EDIAPKTEEIQER--PSESKASLEPKEEVDHISNETEEHEHVLERD 1993
E VD EDI + E + E E + E E+ + ++ E E E +
Sbjct: 2619 SVTEEIVDGEGSFTEDIVEEEESVTEEIVVDEESVTKEIVEDEELVTEEIVEDEGSFTEE 2678
Query: 1994 VQQCE-TIESEAVETKEDTQPSLDLKEDKETEEAETFKTVFSSDEVRSSAVQEEQFGEHT 2170
+ + E + E +E + + D + E EE K + + V+EE+
Sbjct: 2679 IVEDEGSFTEEVIEERSLIEEVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEEEKSVTEE 2738
Query: 2171 EPCSSEIKDESHGKEESVEVKSQETVQDENTEDK-------HDVL--------KVPSTES 2305
+K+E +E+ + V+ + + + ED+ D+L + + E
Sbjct: 2739 VEEKESVKEEV--EEQRLVVEEEGSATEGIVEDRLATEGIVDDILVTEEIVEDGLATDEF 2796
Query: 2306 EKYQGNEPETVL---VSNTGSYEKSEKSPSDLV---LNVDKEELNDEKINVDQVDGTQIM 2467
+ QG+ E VL S T + E SP++ + ++V +E+ N E ++ + V+G+ +
Sbjct: 2797 VEQQGSIIEEVLDDEGSVTEEIVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIVEGS-VT 2855
Query: 2468 EEPI------------------GLDSNGAEAEQIDQNITNETEEILVAKPVSLLDVKSVE 2593
EE I L+ G+ +E+I + + + TEEI+ + + D+
Sbjct: 2856 EEMIKEGLENEVILDEDSITEEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEG 2915
Query: 2594 QMQKPKLESPSEVSE--ETSKTVDXXXXXXXXXXVTLYQEGQVDGSYGLETKEETVSVXX 2767
+ ++ S+V E E +D + +E + + +E KEE SV
Sbjct: 2916 SASEEIIQEESQVEEVVEEVSVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAE 2975
Query: 2768 XXXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKIEEKTDSIELGEIAQE-- 2941
+V+E+I E E+G I +E
Sbjct: 2976 EIVQEEKEG----------------------------SVNEEIIE-----EVGSITEEMV 3002
Query: 2942 ERSVTDLTPLQEESSQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSASPSKELEGETVVX 3121
E+ V+D + EE S E E+ +EK E E + ++EVI+ S S++ E E +
Sbjct: 3003 EQDVSDNEEIVEERSVIEEAEENVWIEK-EVEEEGLDNEEVIDE-EDSVSEQAEEEVYIN 3060
Query: 3122 XXXXXXXXXXXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVAEEIVDEKAKEEV 3301
+ V V E+++E+ EE
Sbjct: 3061 EEILKESSDV--------------------------------EDVKVENELMNEEVNEET 3088
Query: 3302 PMLQIKNEDDATKIHETRVEQARDIGPSLTEICSINQNQPEEQVKEACSKEEQEKEISTN 3481
+ NE+D ++ VE+ S+TE +++ ++V+E S E+ E
Sbjct: 3089 QSVAENNEED-KELDNYVVEETE----SVTEEVVVDEVPNSKEVQEIESIIEEIVEDGLT 3143
Query: 3482 SENIVNETYALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDA 3661
++++V + ++ E +++V + +
Sbjct: 3144 TDDLVGQQGSVIE------------EVVEEVGSDSEGIVEEASITEEVEKKESVTEDILV 3191
Query: 3662 IXXXXXXXXXXXXQDAKIVNNEETTAHESESLKGDNHQEKNAEPVEATQNLDDAEQISRE 3841
++V E+ + E + +G QE E AT+ +D+ E ++ E
Sbjct: 3192 EESVTGDILVEGSVTEEVVGEEKLVSEEIVTEEGSVAQEIVEEDAPATEEIDEIESVTEE 3251
Query: 3842 VT-----VDTE---READITEKI----EKVQEGPTVIETPTIQGEDIESETSLELKEEVD 3985
V VD E E +TE+I KV+E V+E + E+I E + +E+
Sbjct: 3252 VVEEEGPVDEEIVQEEGSVTEEIIQGESKVEE---VVEEQGSENEEIFVE-EVSASQEIV 3307
Query: 3986 QSSKDTEEHEHVLERDIPQCETLKAEAVDTSTVEEAAILKTLETNISEPEAMHSETSLDL 4165
Q+ TEE +LE+ E ++ +V +EE + T E E H +
Sbjct: 3308 QNESGTEE---ILEKVSASQEIVQDGSVTEQIIEEQKPV-TEEVVNEEESITHEIIQEES 3363
Query: 4166 KVDKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDESQGXXXXXXXXXXXT 4345
V+K ++ + V+ N V ++ E+ G TE E
Sbjct: 3364 HVEKVVQQGSVAEEVV-ENPVSVTEEIVEKEGSVTEDIGQE-----------------GY 3405
Query: 4346 VQGESSEEKDVNMLDVQSGES--EKYQEN--EPDISLVSKTENGDKFEEIPSVVEGAGLD 4513
V E EE++ + ++ ES E++ E + + V + + + +E SV E +
Sbjct: 3406 VAEEIVEEEEFDNEEILEEESVAEEFVEEGFDNEEIFVEQISDSEIVKEENSVNEEVLEE 3465
Query: 4514 ETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXXXXXXVTLHQEG-------REEG 4672
E ++ + +L+ E + + EEE S L +EG EEG
Sbjct: 3466 EGSYTEEILEEEGSYTEEI---LEEEGSFTEEILEEEGSYNEEILEEEGSYNEEILEEEG 3522
Query: 4673 SYGLDTKDEAVSVL--------ESRELGEQPQQEELCLANEQENETKLQEEQVDKHEPTK 4828
S+ + +E S ++ E+ E+ + + E L+EE +D + +
Sbjct: 3523 SFTEEILEEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQGSIIEEVLEEEGLDTEKVFE 3582
Query: 4829 EEVSNDQQSPVEEISNEVIQVSS--------ASLSEGPEYETVVE-------AEKIGEEQ 4963
E S + E + V + S S++E + E++ E E+I EEQ
Sbjct: 3583 NEGSATEFEETESFTEVVEETESVNENILEETSINEVQKIESITEDIKEQLVPEEIKEEQ 3642
Query: 4964 V-ADKI-QKSFETGEIVEAHSSLPSSSEEK--EHETVSEKTDDEKVKDAEPI-GDMRERG 5128
+ +++I ++ ++ EI E EE+ E E+ D E++K+ + + +++E
Sbjct: 3643 LDSEEIKEEQLDSEEIKEEQLDSEEIKEEQLVPEEIKEEQLDSEEIKEEQLVPEEIKEEQ 3702
Query: 5129 LDIAETTHLSLPSVDQKED-VDEIHIPSVAL---PLDEQEKVTSTEKGETKSSEAEDDKP 5296
L+ E L S + KE+ +D I L + EQ+ + E E + S E+ K
Sbjct: 3703 LNSEEIKEEQLDSEEIKEEQLDSEEIKEEQLDSEEIKEQKGSVNEEVVEEEGSVTEEIKE 3762
Query: 5297 DEHVDSSTSPMLSEKNDNETQTSKTSEDVCMQQ----EESGTLEVPKPEESKEDKSQXXX 5464
E +S +L E + E+ + E Q EES T EV + E +K
Sbjct: 3763 QE--ESVNEEVLEEVEETESIKEEIVEGGIATQEIIEEESDTKEVVEEEVIDSEK----- 3815
Query: 5465 XXXXXXXXXXDQTLPIETSHTDNTLSSELVSEQDDQSPXXXXXXXXXXXXXAHDVEATSE 5644
+ +P E S TD + +E+ + D
Sbjct: 3816 --LVDAGSVTGEVMPEEVSVTDEVVEEGSTTEEVLEEQKSVNEEVVEDGLTIDDFVGLQG 3873
Query: 5645 RNLPVETSDADNTLSSQLVSETKEEHKLQAGEILPTEIIPRESS-DEALVSMLASRED-- 5815
+ + + L ET E ++ + +I+ +E S +E ++ + E+
Sbjct: 3874 STTEEVVEEDGSAIEKILEEETATEEIVEKQVSVTEDIVEKEGSVNEEIIEEASVAEEII 3933
Query: 5816 ------DKVALQEDNCADDVRE-----TNDIQEERSISVETEESVGETKPKEHEDEIRDA 5962
+++ QE++ ++V + +N+I+EE SV TEE + E + +DE+ +
Sbjct: 3934 QGGSFTEEIVGQEESATEEVIDEEGLISNEIEEEEEKSV-TEEMIEEVEEVSVDDEVEEV 3992
Query: 5963 HVETPTAPIILEENDSETLIAEAKKGNEEINETERTVA---LDHE---EEFVNHEAPKLE 6124
V I+ EE + ++ E E++ E R+V + E EE + E E
Sbjct: 3993 SV---AEEIVEEELVDDEILPEELSATEDVIEEVRSVTDEIVQEESVCEEILEQEVSASE 4049
Query: 6125 ETKDEKS-------------QEIPETAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTP 6265
E D+KS Q++ T TE + + ++ S+ + ++
Sbjct: 4050 EYVDDKSVTDDFVGHERSVIQDVENTESVTEEIAEVDKSVIEEAVEKQGSVTEEIVEEEE 4109
Query: 6266 KQVXXXXXXXXXXTHKVQAEDIFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANT 6445
V+ E E+ KESF E V L S ++E QE +Y +
Sbjct: 4110 LDTEEVLEDKSVTGDVVEQEGSGKDESEAKESFTE-EVDELKSVKEE---DQETEYISRE 4165
Query: 6446 QEERHVSAETEEKVGETKPKESQAEGAEKSDDQVEDESTKKTDVEVAGLENDYPTEEAEH 6625
EE + + E+ E + E + D E++ST + +E N+ EE
Sbjct: 4166 IEEESATEQHSEQ--ELSINKEVVETESLTKDIEEEKSTTQEILEETQSVNEEIVEEERD 4223
Query: 6626 GDETYSTLPVVGIXXXXXXXXXXXRAIND-SASSEVSMIKEPADQEEKKGDDVVESNEKD 6802
DE + + S++ E+ +++ +E K+ + V ++
Sbjct: 4224 TDEVLKEKVSPSEEVIEEQASTTEEFLEERSSTDEIVEVEDLFTEEVKEREGSV---TEE 4280
Query: 6803 FVSDILEAKRLHGDKSGEAEKIKEESGLAGKSLPIEEINLXXXXXXXXXXXXXTREIAQV 6982
V + + + ++ +AE+I EE G + + EE ++ + V
Sbjct: 4281 IVEEGSDTGEIVEEEGSDAEEILEE-GSFNEEIVEEEGSITEEILQGSVTEEFVGQQGSV 4339
Query: 6983 LPREEILISSSPLSAEEQEHVIS---DEKQEEREPQQDFNGSTSEKISLQVEHLKDFETS 7153
+ EEI+ + S + ++ + DE++ E ++ S+ E + +E + + E S
Sbjct: 4340 I--EEIVETESAIEERVEDESATEEVDERESVTEVVEEEVSSSDEVVEGSIEEVIENEGS 4397
Query: 7154 KKEQKDETHETVXXXXXXXXXXXXXXXXXXXXXXSSEVKKDNKDARE-----------LE 7300
E+ E HE + EV ++ + E ++
Sbjct: 4398 VTEEILE-HEVSADENFVGQAVSVIEEVEGTESVTEEVVEETESVSEEIVEVSPTENVVQ 4456
Query: 7301 VGNDFVSRDGEKEEVPHNAL-------ENEEEMNEVVASEKQISDPVGVIKKASEAEHED 7459
+ + D E++E N ++ E E +++E+ + E+
Sbjct: 4457 QTDSVIEEDVEQKEGSFNEEIDIRELGDDGVEEREKISTEEVVGQDKSATGDVEESSSTG 4516
Query: 7460 PVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPKEAIGEELKVPSSKVLDDIQENSNTEA 7639
V+++ S +D + E + + +EVS+ E + + + E+++ SS +D++E S E
Sbjct: 4517 DVEEVSSTEDEE---EVSSTEGLEEVSSTEGLEEVSNTEDVEEVSS--TEDVEEGSVAEN 4571
Query: 7640 VTNFADRDLPVQNLSELIQSHQSPNQ--VEETSFEFNKAQEDKKEE-------TVDALIT 7792
V V ++I S Q + E S E N E EE +V+
Sbjct: 4572 VKETKSITEEVSVEEDIITDKVSVEQEVMAEASVEENILTEVPVEEEIMTEKLSVEDKAL 4631
Query: 7793 NVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQEDIGTYVKVQ---VPDDEIKGDGHD 7963
N ++ + + E + + + + ++ V+E V+ V ++ + D
Sbjct: 4632 NEKIMSEEEIVIEDGNVHEVVPAEVSVTEEIPGVEETTNNESHVKGENVVNEVVVDDNSV 4691
Query: 7964 SVAAQKEETSSIE----EKREVEHVKAEMEDAIKHEVSVEEKNNTSENIDHEAAKEIEQE 8131
+ Q ++ SSIE + ++V H K E D+ + EV +E + S + K+IE E
Sbjct: 4692 NDEIQFDDDSSIEIYTVDSKDVFH-KEENYDSFREEVRSDENIHISRKKNENFVKKIENE 4750
Query: 8132 EGKQTNIVXXXXXXXXXXXNQESFNNVKE--TDDAIDKTQPEIRDIESLSSVSKTQDKPE 8305
+ ++ S KE T++ + + E +E + +++
Sbjct: 4751 KSSVGHVPTEYTSKENIAEEVPSHIMFKENVTEEVPKEVKYEENTVEEVFEEVTSKENII 4810
Query: 8306 PEYEVPNQQKREITNEVPSLENS 8374
E + I EVP + S
Sbjct: 4811 EEAPGDINSEENIIEEVPEVVTS 4833
Score = 240 bits (612), Expect = 3e-61
Identities = 536/2578 (20%), Positives = 982/2578 (37%), Gaps = 163/2578 (6%)
Frame = +2
Query: 344 EPQSLN----EKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQ 511
E +S+N K+ D + IL L + EE+ E+ + ++ E + E+
Sbjct: 2428 ESESVNGEIINKESDAEEILETEFLTEEVVGQAGSTSEEIVEEEGSVTKEVEEKESVTEE 2487
Query: 512 EEDIGNISKVLTDTTPVKVDEYDIEKSL-NSVCEEIPIKTDEVREETDSRTVETSVNGTE 688
D G++++ L D V + + S+ + EE + +R+ET+ V E
Sbjct: 2488 LVDEGSVTEELVDEGSVTEEVVEQGGSIAQEIVEEESATEEIIRDETNVEEV------LE 2541
Query: 689 AEHNATVSVEEISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIV 868
E +AT EEI ++G T D G + +V E T E K
Sbjct: 2542 KEGSAT---EEIVQDGSGT------NDFVGKQGSVIEEV------VEEEISTTEEKLK-- 2584
Query: 869 NTEETTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDKEKE--EDIIQNIEE 1042
EE +A E + ++E++ +E+ E T+N ++S E VD E EDI++ E
Sbjct: 2585 --EEASAIE-EFVEEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIVEEEES 2641
Query: 1043 VQESPSVMESPTIQGEDIESKASLDHE--EEMDKITKDTEEQEHVLVRDVPVPQSETLVT 1216
V E V++ ++ E +E + + E E+ T++ E E +V + +L+
Sbjct: 2642 VTEE-IVVDEESVTKEIVEDEELVTEEIVEDEGSFTEEIVEDEGSFTEEVI--EERSLIE 2698
Query: 1217 EAKTAETFSV-QEAEILKTNINESEAHSAIGGEEDG--QETKENTEPSKDLKDDK---EQ 1378
E + ET + +E ++K I+E I EE +E +E +++++ + E+
Sbjct: 2699 EVEDTETVAEKEEGSVIKEIIDEKSLTEKIVEEEKSVTEEVEEKESVKEEVEEQRLVVEE 2758
Query: 1379 EDSET-------------VKTIISSDEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESI 1519
E S T V I+ ++E+ + + F E E+ DD E I
Sbjct: 2759 EGSATEGIVEDRLATEGIVDDILVTEEIVEDGLATDEFVEQQGSIIEEVLDDEGSVTEEI 2818
Query: 1520 EVKAKETGPEIETAVDGESVHE----IETTERVLLEAXXXXXXXXXXXXXXPSLN----A 1675
+E G E V+G SV E IE ++E L+
Sbjct: 2819 ---VEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIVEGSVTEEMIKEGLENEVILDEDSIT 2875
Query: 1676 IEKAETXXXXXXXXXXXXXXXXXTSVHESES-----LKENAEPVEAVKNSDGTEQISREV 1840
E E V E S ++E + E ++ E++ EV
Sbjct: 2876 EEALEKEGSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEGSASEEIIQEESQVEEVVEEV 2935
Query: 1841 TV-DRAKEEDIAPKTEEIQERPSESKASLEPKEEVDHISNETEEHEH------------- 1978
+V D EED E ++E ++ +E KEE ++ E + E
Sbjct: 2936 SVIDEIVEEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGSVNEEIIEEVG 2995
Query: 1979 -VLERDVQQCETIESEAVETK---EDTQPSLDLKEDKETEEAETFKTVFSSDEVRSSAVQ 2146
+ E V+Q + E VE + E+ + ++ ++++ E E + + + D V A +
Sbjct: 2996 SITEEMVEQDVSDNEEIVEERSVIEEAEENVWIEKEVEEEGLDNEEVIDEEDSVSEQAEE 3055
Query: 2147 EEQFGEHTEPCSSEIKDESHGKEESVEVKSQET--VQDENTEDKH-DVLKVPSTESEKYQ 2317
E E SS+++D E E ++ET V + N EDK D V TES
Sbjct: 3056 EVYINEEILKESSDVEDVKVENELMNEEVNEETQSVAENNEEDKELDNYVVEETESVT-- 3113
Query: 2318 GNEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELNDEKINVDQVDGTQ--IMEE---PIG 2482
E V+V + ++ ++ S + EE+ ++ + D + G Q ++EE +G
Sbjct: 3114 ----EEVVVDEVPNSKEVQEIESII------EEIVEDGLTTDDLVGQQGSVIEEVVEEVG 3163
Query: 2483 LDSNG-AEAEQIDQNITNE---TEEILVAKPVS--LLDVKSV--EQMQKPKLESPS---- 2626
DS G E I + + + TE+ILV + V+ +L SV E + + KL S
Sbjct: 3164 SDSEGIVEEASITEEVEKKESVTEDILVEESVTGDILVEGSVTEEVVGEEKLVSEEIVTE 3223
Query: 2627 ------EVSEETSKTVDXXXXXXXXXXVTLYQEGQVDGSYGLETKEETVSVXXXXXXXXX 2788
E+ EE + + + +EG VD E T +
Sbjct: 3224 EGSVAQEIVEEDAPATEEIDEIESVTEEVVEEEGPVDEEIVQEEGSVTEEIIQGESKVEE 3283
Query: 2789 XXXXR-SVIDPTPLQKPTXXXXXXXXXXXXKTVDEKIEEKTDSIELGEIAQEERSVTDLT 2965
+ S + +++ + + + EK+ + ++ G + E+ + +
Sbjct: 3284 VVEEQGSENEEIFVEEVSASQEIVQNESGTEEILEKVSASQEIVQDGSVT--EQIIEEQK 3341
Query: 2966 PLQEESSQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSASPSKELEGETVVXXXXXXXXX 3145
P+ EE NE+E T HE EE ++V++ S ++E+ V
Sbjct: 3342 PVTEEVV--NEEESIT----HEIIQEESHVEKVVQ--QGSVAEEVVENPVSVTEEIVEKE 3393
Query: 3146 XXXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVAEEIVDEKA-KEEVPMLQIKN 3322
+ E V+ + +VAEE V+E EE+ + QI +
Sbjct: 3394 GSVTEDIGQEGYVAEEIVEEEEFDNEEIL-----EEESVAEEFVEEGFDNEEIFVEQISD 3448
Query: 3323 EDDATKIHETRVEQARDIGPSLTEICSINQNQPEEQVKEACSKEEQ-------------E 3463
+ + + E + G EI + EE ++E S E+ E
Sbjct: 3449 SEIVKEENSVNEEVLEEEGSYTEEILEEEGSYTEEILEEEGSFTEEILEEEGSYNEEILE 3508
Query: 3464 KEISTNSENIVNETYALHSVXXXXXXXXX--------NGESLDDVETTKSXXXXXXXXXX 3619
+E S N E + E + N E +++ T
Sbjct: 3509 EEGSYNEEILEEEGSFTEEILEEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQGSIIEE 3568
Query: 3620 XXXXXXXXXPRL-----DAIXXXXXXXXXXXXQDAKIVNN---EETTAHESESLKGDNHQ 3775
++ A ++ + VN EET+ +E + ++
Sbjct: 3569 VLEEEGLDTEKVFENEGSATEFEETESFTEVVEETESVNENILEETSINEVQKIESITED 3628
Query: 3776 EKNA-EPVEATQNLDDAEQISREV--TVDTEREADITEKIEKVQEGPTVIETPTIQGEDI 3946
K P E + D+E+I E + + + E +E+I++ Q P I+ + E+I
Sbjct: 3629 IKEQLVPEEIKEEQLDSEEIKEEQLDSEEIKEEQLDSEEIKEEQLVPEEIKEEQLDSEEI 3688
Query: 3947 ESETSL--ELKEEVDQSSKDTEEH---EHVLERDIPQCETLKAEAVDTSTVEE--AAILK 4105
+ E + E+KEE S + EE E + E + E +K E +D+ ++E ++ +
Sbjct: 3689 KEEQLVPEEIKEEQLNSEEIKEEQLDSEEIKEEQLDS-EEIKEEQLDSEEIKEQKGSVNE 3747
Query: 4106 TL---ETNISEPEAMHSETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEP 4276
+ E +++E E E S++ +V +E +E E++K I + T + EE + E
Sbjct: 3748 EVVEEEGSVTE-EIKEQEESVNEEVLEEVEETESIKEEIVEGGIATQEIIEEE-SDTKEV 3805
Query: 4277 CSSEIKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQSGESEKYQENEPDISLVSKT 4456
E+ D + +V GE E +V++ D E +E + K+
Sbjct: 3806 VEEEVIDSEK-------LVDAGSVTGEVMPE-EVSVTDEVVEEGSTTEE----VLEEQKS 3853
Query: 4457 ENGDKFEEIPSVVEGAGLDETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXXXXX 4636
N + E+ ++ + GL +T + + + S +++ L EEET+
Sbjct: 3854 VNEEVVEDGLTIDDFVGLQGSTTEEVVEEDGSAIEKIL----EEETATEEIVEKQVSVTE 3909
Query: 4637 XVTLHQEGREEGSYGLDTKDEAVSVLESRELGEQPQQEELCLANEQENETKLQEEQVDKH 4816
+ +EGS + +EA E + G EE+ E E + EE + +
Sbjct: 3910 DIV-----EKEGSVNEEIIEEASVAEEIIQGGSFT--EEIVGQEESATEEVIDEEGLISN 3962
Query: 4817 EPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQVADKI---QKS 4987
E +EE ++S EE+ EV +VS E E V AE+I EE++ D ++
Sbjct: 3963 EIEEEE----EKSVTEEMIEEVEEVSVDD-----EVEEVSVAEEIVEEELVDDEILPEEL 4013
Query: 4988 FETGEIVEAHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAETTHLSLPS 5167
T +++E S+ + E + E+V E+ +++V +E D + D +
Sbjct: 4014 SATEDVIEEVRSV--TDEIVQEESVCEEILEQEVSASEEYVDDKSVTDDFVGHERSVIQD 4071
Query: 5168 VDQKEDVDEIHIPSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSPMLSEKND 5347
V+ E V E + E +K E E + S E+ +E +D T +L +K+
Sbjct: 4072 VENTESVTE--------EIAEVDKSVIEEAVEKQGSVTEEIVEEEELD--TEEVLEDKS- 4120
Query: 5348 NETQTSKTSEDVCMQQEESGTLEVPKPEESKEDKSQXXXXXXXXXXXXXDQTLPIETSHT 5527
+ DV ++QE SG +ES+ +S DQ ET +
Sbjct: 4121 -------VTGDV-VEQEGSGK------DESEAKESFTEEVDELKSVKEEDQ----ETEYI 4162
Query: 5528 DNTLSSELVSEQDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDADNTLSSQLVSE 5707
+ E +EQ + D+E E++ E + +++ ++V E
Sbjct: 4163 SREIEEESATEQHSEQELSINKEVVETESLTKDIE--EEKSTTQEILEETQSVNEEIVEE 4220
Query: 5708 TKEEHKLQAGEILPTEIIPRESSDEALVSMLASREDDKVALQEDNCADDVRE-----TND 5872
++ ++ ++ P+E + E + + D++ ED ++V+E T +
Sbjct: 4221 ERDTDEVLKEKVSPSEEVIEEQASTTEEFLEERSSTDEIVEVEDLFTEEVKEREGSVTEE 4280
Query: 5873 IQEERSISVETEESVGETKPKEHEDEIRDAHVETPTAPI---ILEENDSETLIAEAKKGN 6043
I EE S + E E G + E+ + + I IL+ + +E + +
Sbjct: 4281 IVEEGSDTGEIVEEEGSDAEEILEEGSFNEEIVEEEGSITEEILQGSVTEEFVGQQGSVI 4340
Query: 6044 EEINETERTVALDHEEEFVNHEAPKLEETKDEKSQEIPETAKATETTIDQTLPIGTSQAD 6223
EEI ETE + E+E E + E + +E+ + + E +I++ + S +
Sbjct: 4341 EEIVETESAIEERVEDESATEEVDERESVTEVVEEEVSSSDEVVEGSIEEVIENEGSVTE 4400
Query: 6224 QTPSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETVPKESFIEAPVSMLASGED 6403
+ D+ Q T V E + TE+V +E +P + D
Sbjct: 4401 EILEHEVSADENFVGQAVSVIEEVEG-TESVTEEVVEETESVSEEIVEVSPTENVVQQTD 4459
Query: 6404 ----EPVTPQEGDYAANTQ---------EERHVSAETEEKVGETKPKESQAEGAEKSDDQ 6544
E V +EG + EER TEE VG+ K E + + D
Sbjct: 4460 SVIEEDVEQKEGSFNEEIDIRELGDDGVEERE-KISTEEVVGQDKSATGDVEESSSTGD- 4517
Query: 6545 VEDESTKKTDVEVAGLENDYPTEEAEHGDETYSTLPVVGIXXXXXXXXXX-------XRA 6703
VE+ S+ + + EV+ E E +E +T V + ++
Sbjct: 4518 VEEVSSTEDEEEVSSTEGLEEVSSTEGLEEVSNTEDVEEVSSTEDVEEGSVAENVKETKS 4577
Query: 6704 INDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDILEAKRLHGDKSGEAEKIKEESG 6883
I + S E +I + E++ + S E++ ++++ + + +K +K E
Sbjct: 4578 ITEEVSVEEDIITDKVSVEQEVMAEA--SVEENILTEVPVEEEIMTEKLSVEDKALNEKI 4635
Query: 6884 LAGKSLPIEEINLXXXXXXXXXXXXXTREIAQVLPREEILISSSPLSAEEQEHVISDEKQ 7063
++ + + IE+ N + +V+P E + P EE + S K
Sbjct: 4636 MSEEEIVIEDGN-----------------VHEVVPAEVSVTEEIP-GVEETTNNESHVKG 4677
Query: 7064 EE--REPQQDFNGSTSEKISLQVEHLKDFETSKKEQKDETHETVXXXXXXXXXXXXXXXX 7237
E E D N E +Q + E + KD H+
Sbjct: 4678 ENVVNEVVVDDNSVNDE---IQFDDDSSIEIYTVDSKDVFHKEENYDSFREEVRSDENIH 4734
Query: 7238 XXXXXXSSEVKK-DNKDARELEVGNDFVSRDGEKEEVPHNALENEEEMNEVVASEKQISD 7414
+ VKK +N+ + V ++ S++ EEVP + + E EV K +
Sbjct: 4735 ISRKKNENFVKKIENEKSSVGHVPTEYTSKENIAEEVPSHIMFKENVTEEVPKEVKYEEN 4794
Query: 7415 PVGVIKKASEAEHEDPVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPKEAIGEELKV 7588
V E+ +++ S ++ E+AP D + E + E VP+ EE+ V
Sbjct: 4795 TV-----------EEVFEEVTSKENI---IEEAPGDINSEENIIEEVPEVVTSEEIVV 4838
Score = 211 bits (537), Expect = 2e-52
Identities = 474/2349 (20%), Positives = 882/2349 (37%), Gaps = 222/2349 (9%)
Frame = +2
Query: 1757 ESESLKENAEPVEAVKNSDGTEQISREVTVDRAKEEDIAPKTEEIQERPSESKASLEPKE 1936
ESE + +E ++ ++ +I + + ++ E+ TEE + ++ +LE +
Sbjct: 5 ESEEFPKEKYNIEDMEETEKENEIEKIMDENKETEQTEEGNTEEFVQEKELNQETLENEI 64
Query: 1937 EVDHISNE-----TEEHEHVLERDVQQCETIESEAVETKEDTQ----------------- 2050
VDHI E +E E VLE + +E+ + E+ +
Sbjct: 65 IVDHIKEEEDTRNVKEQESVLEESPIEELPVENNIGKINEEVEEFILNEIPLEEQVPKEL 124
Query: 2051 PSLDLKE--------DKETEEAETFKTVFSSDEVRSSAVQEEQFGEHTEPCSSEIKDESH 2206
P +++E D+ ET TV D + + EE+ E + S EI E
Sbjct: 125 PQEEIEEIVVEELPIDEHLSSEET--TVTEEDTFKGQLINEEKPVEE-KSVSEEIPVEEK 181
Query: 2207 GKEESVEVKSQETVQDENTEDKHDVLKVPSTESEKYQGNEPETVLVSNTGSYEKSEKSPS 2386
E + V+ + ++ E+K+ ++P E + E VS E+ S
Sbjct: 182 SVSEEIPVEEKSVSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEENVSEE 241
Query: 2387 DLVLNVDKEELNDEKINVDQVDGTQIMEEPIGLDSNGAEAEQIDQNIT----------NE 2536
+ V++E +++E ++ +I E I ++ + E + + IT NE
Sbjct: 242 ---IPVEEENVSEEIPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNE 298
Query: 2537 TEEILVAKPVSLLDVKSVEQMQKPKLESPSEVSEETSKT------------------VDX 2662
E + PV D EQ+ P E+ EE T D
Sbjct: 299 IETVNEEMPVE--DETLTEQISSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDD 356
Query: 2663 XXXXXXXXXVTLYQEGQVDGSYGLE------TKEETVSVXXXXXXXXXXXXXRSVIDPTP 2824
+E V G E +EE SV + +
Sbjct: 357 IPEEQIITEKVQEEEEFVTGELSEEDIINEKVQEEDESVTEELPEEDIINEKVQEEEESA 416
Query: 2825 LQKPTXXXXXXXXXXXXKTVDEKIEEKTDSIELGE----------IAQEERSVTDLTPLQ 2974
Q+ + V++ + +K + + + + EE VT P++
Sbjct: 417 YQEIVQDGSVTKDVEYKELVNDDVRDKENFVIEEDPFKGQLINEGLPVEEEFVTKELPVK 476
Query: 2975 EESSQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSASPSKELEGETVVXXXXXXXXXXXX 3154
EES E++ + K P E EV E+ S + + +E E V
Sbjct: 477 EESVFEELTEEDQSVTKEIPVEEHSVFKEVDEIESVT-EEIVEEEGSVNEEVEEEVSVSG 535
Query: 3155 XXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHV----TVAEEIVDEKAK--EEVPMLQI 3316
+E + V + V + +E+IV+E+ EE +I
Sbjct: 536 EVDETEYVTEEVEETELVNEEVLKEEGSASEKVVKEEGSASEKIVEEEGSVTEETASEEI 595
Query: 3317 KNEDDATKIHETRVEQARDIGPSLTEICSINQNQPEE--QVKEACSKEEQEKEISTNSEN 3490
E+ + + E D G S+TE S + EE ++E+ S+ E E+S + E
Sbjct: 596 VEEEGSVTEESSSEEIVEDEG-SVTEESSSEEIVEEEGSVIEESASEVIVEDEVSASKEI 654
Query: 3491 IVNETYALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXX 3670
+ +E V G D+V+ T+S D I
Sbjct: 655 VEDEASVTEEV------VEEEGAVSDEVQVTESVE--------------------DEIIN 688
Query: 3671 XXXXXXXXXXQDAKIVNNEETTAHESESLKGDNHQEKNAEPVEATQNLDD--------AE 3826
Q+A + +E + ++ +E E VE T+ +D+ E
Sbjct: 689 QGIVDEVIVEQEASV--TDEIVKEDESVIEEIAVEETVTEVVEETKPMDEEIVDQGSVVE 746
Query: 3827 QISREVTVDTEREADITEKIEKVQEGPTVIETPTIQGEDIE--SETSLELKEEVDQSSKD 4000
+ + T+D E D +E V+E T+ E QG E E L +E +++
Sbjct: 747 NVEEKKTMD-EEIVDQGSVVENVEEKKTMDEEIGDQGSVAEKVEEEELVTEEVIEREGSI 805
Query: 4001 TEE--HEHVLERDIPQCETLKAEAVDTSTVEEAAILKTLETNISEPEAMHSE-TSLDLKV 4171
E+ E + ++ Q E + + ++ + + + +I E + E + V
Sbjct: 806 NEDIVKEASITEEVEQIEPVTGKVEKIESITDEIKEQLVPEDIKEEQLDFEEIVAQRASV 865
Query: 4172 DKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEP-----CSSEIKDESQGXXXXXXXXX 4336
+ E+ E ++ + E S+ EE G TE S+E+ E QG
Sbjct: 866 NDEKVEVASITEEVEEEEKSVSEEVLEEEGSTTEKVVEEGSSTEVVVEEQGSVSEEVLEE 925
Query: 4337 XXTVQGESSEEK---DVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEEIPSVVEGAG 4507
+ E EE+ N+L+ +S S+ E E + ++ + FE+ EG+
Sbjct: 926 EGSTTEEVVEEQGSVTENLLEEESA-SQGIVEKEEFVDEEDSVKDQNVFEK-----EGSV 979
Query: 4508 LDETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXXXXXXVTLHQEGREEGSYGLD 4687
++ + L E K+ L T EE + Q+G + +
Sbjct: 980 TEQLVEEEKGLINEDNEKEELITEMSEEIKSVNEEIEETDLSTEEIIKQQGLATYEFVEE 1039
Query: 4688 TKDEAVSVLESRELGEQPQQEELCLANEQENETKLQEEQVDKHEPTKEEVSNDQQSPVEE 4867
K +LE + ++ + EL + + + EE +++ + EEV ++ S EE
Sbjct: 1040 EKSLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVIEEEKSVSEEVL-EEGSATEE 1098
Query: 4868 ISNE----------------VIQVSSAS---LSEGPEYETVVEAEKIGEEQV-------- 4966
+ E V++ SA+ + EG E VVE + EE +
Sbjct: 1099 VVEEGSCTEIVVEKGSDTEIVVEEGSATEIVVEEGSATEVVVEEGSVSEEMLEEEGSATE 1158
Query: 4967 --------ADKIQKS----FETGEIVEAHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIG 5110
+D +QKS GEI ++ S EK S DDE K P
Sbjct: 1159 EVVEEGLSSDNVQKSKGVIENVGEIYSVKTAKDESMNEKIPLEKSSFVDDESFKGQGP-- 1216
Query: 5111 DMRERGLDIAETTHLSLPSVDQKEDVDEIHIPSVALPLDE--QEKVTSTE---KGETKSS 5275
T ++S+ V+ ++ ++E H P ++E E +T+ + +GET++
Sbjct: 1217 -----------TDNVSVEDVNSEDIINE-HTPLEETKIEELPTEYITTADIHTRGETETK 1264
Query: 5276 -EAEDDKPDEHVDSSTSPMLSEKNDNETQTSKTSEDVCMQQEESGTLEVPKPEESKEDKS 5452
+K +E V+ + + Q K +E++ +++E V +P ++E +
Sbjct: 1265 YNLIYEKINEEVEKA-----------KFQEEKITENIPVERESVTEDIVQEPSLAQEVEQ 1313
Query: 5453 QXXXXXXXXXXXXXDQTLPIETSHTDNTL------SSELVSEQDDQSPXXXXXXXXXXXX 5614
+ ++ + E S T+N + + E++ E + +
Sbjct: 1314 KESDTNEIEETKLANEKIIPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEEEVSACEE 1373
Query: 5615 XAHDVEATSERNLPVETSDADNTLSSQLVS--ETKEEHKLQAGEILPTEIIPRESSDEAL 5788
+ E++SE + E S ++ + + S E EE + + EI+ E ESS E +
Sbjct: 1374 IVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEE----ESSSEEI 1429
Query: 5789 VSMLASRE---DDKVALQEDNCADDVRETNDIQEERSISVET--EESVGETKPKEHEDEI 5953
+ ++S E +++ ++ E+ ++V T ++++ S+S E EE G + + +
Sbjct: 1430 IEEVSSTEEVLEEEGSVTEEIVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSV 1489
Query: 5954 RDAHVETPTA-PIILEENDSETLIAEAKKG-------NEEINETERTVALDHE--EEFVN 6103
+ VET ++ +LE+ S ++G +EE++ TE+ +D EE V
Sbjct: 1490 IEEIVETESSTEKVLEDVGSNVEEIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEEIVE 1549
Query: 6104 HEAPKLEETKDEK---SQEIPETAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTPKQV 6274
EE E+ S+EI E TE +++ I ++ +T S+ ++ K+V
Sbjct: 1550 KVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLI--NEVGETESVT---EEIVQKEV 1604
Query: 6275 XXXXXXXXXXTHKVQAEDIFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEE 6454
+ E + E + KES +E V G + VT + DY + +E
Sbjct: 1605 -------SDAEEVLGQEGSMNEEILEKESIVEEIV-----GPEGSVTEEIVDYGSFAEEV 1652
Query: 6455 RHVSAETEEKVG-ETKPKESQAEGAEKSDDQVEDESTKKTDVEVAGLENDYPTEEAEHGD 6631
+ TEE V E E E ++++ +ES +E G ND +E
Sbjct: 1653 KEEELVTEEAVQYEGSVTEEIKEEESITENEAIEESAFAEIIEEKGPNNDEIVKE----- 1707
Query: 6632 ETYSTLPVVGIXXXXXXXXXXXRAINDS-ASSEVSMIKEPADQEEKKGDDVVESNEKDFV 6808
E T +V + +N+ E S+ ++P + E +D+VE
Sbjct: 1708 EGLDTEEIVNEVSVTDEVIEEEKLVNEQIVGEERSVTEKPVEVERSATEDLVEEG----- 1762
Query: 6809 SDILEAKRLHGDKSGE-------AEKIKEESGLAGKSLPIEEINLXXXXXXXXXXXXXTR 6967
+ + E +H + E AE+I EE + EE+++
Sbjct: 1763 ASVTEKVSVHEGSTTEQILDESVAEEIVEEEVSVDDKIIEEEVSVDEVVEEEGSVIEEIV 1822
Query: 6968 EIAQVLPREEILISSSPLSAEEQEHVISDE------------KQEEREPQQDFNGSTSEK 7111
E + +P E I LS E+ V+ DE EE E D GS +E+
Sbjct: 1823 EEEESVPEE---ILEEELSGSEE--VLEDEWVTDAFMGQEGSVIEEIEEIVDGEGSITEE 1877
Query: 7112 ISLQVEHLKDFETSKKEQKDETHETVXXXXXXXXXXXXXXXXXXXXXXSSEVKKDNKDAR 7291
I VE E +E+ E + + V + ++++
Sbjct: 1878 I---VEDGSANEKIVEEEPSRVEEVLGKEGFVIEEIIEEGSVIEQVEDTKTVSEKSEESS 1934
Query: 7292 ELEVGNDFVSRDGEKEEVPHNALENEEEMNEVV------ASEKQISD--PVGVIKKASEA 7447
+E V E+E + +E EE + E + +EK + D P + +++
Sbjct: 1935 AIEE----VKEVKEEESISEKIVEKEESVTEEIVRQEESTTEKIVKDVSPTEDFVEQTDS 1990
Query: 7448 EHEDPVDDIKSNDD--RDFPTEQAPKDQSDE----VSADETVPKEAIGEELKVPSSKVLD 7609
E ++ SN + D +++ D+ ++ V+A T K+++ +E+ S+ +
Sbjct: 1991 VTEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSVNAQVTCEKKSVTKEIVDEVSRTEE 2050
Query: 7610 DIQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQVEETSFEFNKAQEDK---KEETVD 7780
++EN +VT D V E+I+ +V E + ED +E D
Sbjct: 2051 IVEENG---SVTEGVDETGSV--TEEIIEEATVTEEVVEDGSVTEEVVEDGSVIQEVVED 2105
Query: 7781 ALITNVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQEDI---GTYVKVQVPDDEIKG 7951
+T VQ E ++ +EI E+E +N+ +V+E++ G + + +E++
Sbjct: 2106 GSVTEEIVQ-------ENGSVTEEIVEEEGSVNE--EVEEEVSVSGEVDETEYVTEEVEE 2156
Query: 7952 DGHDSVAAQKEETSSIEEKRE-----VEHVKAEMEDAIKHEVSVEEKNNTSENIDHEAA- 8113
+G +EE S +EE E VE + E E ++ E+ EE + E ++ E +
Sbjct: 2157 EGSVVEEIVEEEGSVVEEIVEEEGSVVEEI-VEEEGSVVEEIVEEEGSVVEEIVEEEGSV 2215
Query: 8114 -KEIEQEEG 8137
+EI +EEG
Sbjct: 2216 VEEIVEEEG 2224
Score = 190 bits (483), Expect = 3e-46
Identities = 442/2124 (20%), Positives = 795/2124 (36%), Gaps = 84/2124 (3%)
Frame = +2
Query: 2237 QETVQDENTEDKHDVLKVPSTESEKYQGNEPETVLVSNTGSYEKSEKSPSDLVLNVDKEE 2416
+E +E ++K+++ + TE E NE E ++ N + + E + + V ++E
Sbjct: 2 KELESEEFPKEKYNIEDMEETEKE----NEIEKIMDENKETEQTEEGNTEEFV---QEKE 54
Query: 2417 LNDE----KINVDQV----DGTQIMEEPIGLDSNGAEAEQIDQNITNETEEILVAKPVSL 2572
LN E +I VD + D + E+ L+ + E ++ NI EE+ + L
Sbjct: 55 LNQETLENEIIVDHIKEEEDTRNVKEQESVLEESPIEELPVENNIGKINEEV---EEFIL 111
Query: 2573 LDVKSVEQMQKPKLESPSEVSEETSKTVDXXXXXXXXXXVTLYQEGQVDGSYGLETK--- 2743
++ EQ+ K E P E EE T+ +E G E K
Sbjct: 112 NEIPLEEQVPK---ELPQEEIEEIVVEELPIDEHLSSEETTVTEEDTFKGQLINEEKPVE 168
Query: 2744 ----EETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKI--EEK 2905
E + V +SV + P+++ K V E+I EEK
Sbjct: 169 EKSVSEEIPVEEKSVSEEIPVEEKSVSEEIPVEE--------------KNVSEEIPVEEK 214
Query: 2906 TDSIELGEIAQEERSVTDLTPLQEESSQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSAS 3085
S EI EE++V++ P++EE+ +E + + P EE S+E+ E A
Sbjct: 215 NVS---EEIPVEEKNVSEEIPVEEENVSEEIPVEEENVSEEIPVEEENVSEEIPEGGIAI 271
Query: 3086 PSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETV-QTVXXXXXXXXXXXXQDHVTV 3262
++ ETV +ETV + + +H V
Sbjct: 272 EDVPVDEETV-------TEEITVDEKIYDKLPNEIETVNEEMPVEDETLTEQISSEHERV 324
Query: 3263 AEEIVDEK---AKEEVPMLQIKNEDDATKIHETRVEQARDIGPSLTEICSINQNQPEEQV 3433
EEI++EK EE L + ++ + EQ E + E+ +
Sbjct: 325 PEEIIEEKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQEEEEFVTGELSEEDII 384
Query: 3434 KEACSKEEQEKEISTNSENIVNETYALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXXX 3613
E +E++ E+I+NE +G DVE +
Sbjct: 385 NEKVQEEDESVTEELPEEDIINEK-VQEEEESAYQEIVQDGSVTKDVEYKELVNDDVRDK 443
Query: 3614 XXXXXXXXXXXPRLDAIXXXXXXXXXXXXQDAKIVNNEETTAHES--ESLKGDNHQEKNA 3787
+L + + V E ES E L ++
Sbjct: 444 ENFVIEEDPFKGQL---------INEGLPVEEEFVTKELPVKEESVFEELTEEDQSVTKE 494
Query: 3788 EPVE---ATQNLDDAEQISREVTVDTEREADITEKI-EKVQEGPTVIETPTIQGEDIESE 3955
PVE + +D+ E ++ E+ E E + E++ E+V V ET + E E+E
Sbjct: 495 IPVEEHSVFKEVDEIESVTEEI---VEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEETE 551
Query: 3956 TSLE--LKEEVDQSSKDTEEHEHVLERDIPQCETLKAEAVDTSTVEEAAIL--KTLETNI 4123
E LKEE S K +E E+ + + ++ E VEE + ++ I
Sbjct: 552 LVNEEVLKEEGSASEKVVKEEGSASEKIVEEEGSVTEETASEEIVEEEGSVTEESSSEEI 611
Query: 4124 SEPEAMHSETSLDLKVDKEQKEA--ETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSE--- 4288
E E +E S ++ +E+ E+ VI +EV S E+ TE E
Sbjct: 612 VEDEGSVTEESSSEEIVEEEGSVIEESASEVIVEDEVSASKEIVEDEASVTEEVVEEEGA 671
Query: 4289 IKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLD--VQSGES--EKYQENEPDISLVSKT 4456
+ DE Q + E E++ ++ D V+ ES E+ E +V +T
Sbjct: 672 VSDEVQVTESVEDEIINQGIVDEVIVEQEASVTDEIVKEDESVIEEIAVEETVTEVVEET 731
Query: 4457 ENGDKFEEI---PSVVEGAGLDETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXX 4627
+ D EEI SVVE ++ T ++ ++D SVV+ + + +E
Sbjct: 732 KPMD--EEIVDQGSVVENVE-EKKTMDEEIVDQGSVVENVEEKKTMDEEIGDQGSVAEKV 788
Query: 4628 XXXXVTLHQEGREEGSYGLDTKDEAVSVLESREL----GEQPQQEELC-LANEQENETKL 4792
+ + EGS D EA E ++ G+ + E + EQ +
Sbjct: 789 EEEELVTEEVIEREGSINEDIVKEASITEEVEQIEPVTGKVEKIESITDEIKEQLVPEDI 848
Query: 4793 QEEQVDKHEPTKEEVS-NDQQSPVEEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQVA 4969
+EEQ+D E + S ND++ V I+ EV + E E V+E E E+V
Sbjct: 849 KEEQLDFEEIVAQRASVNDEKVEVASITEEVEE------EEKSVSEEVLEEEGSTTEKV- 901
Query: 4970 DKIQKSFETGEIVEAHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAETT 5149
+++ T +VE S+ E+E T E +++ G + E ++ E
Sbjct: 902 --VEEGSSTEVVVEEQGSVSEEVLEEEGSTTEEVVEEQ--------GSVTE---NLLEEE 948
Query: 5150 HLSLPSVDQKEDVDEIHIPSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSPM 5329
S V+++E VDE +++ VT E K ED++ +E + + S
Sbjct: 949 SASQGIVEKEEFVDEEDSVKDQNVFEKEGSVTEQLVEEEKGLINEDNEKEELI-TEMSEE 1007
Query: 5330 LSEKNDNETQTSKTSEDVCMQQEESGTLEVPKPEESKEDK---SQXXXXXXXXXXXXXDQ 5500
+ N+ +T ++E++ ++Q+ T E + E+S DK + +
Sbjct: 1008 IKSVNEEIEETDLSTEEI-IKQQGLATYEFVEEEKSLTDKLLEEESVTKEVGETELSTQE 1066
Query: 5501 TLPIETSHTDNTLSSE-LVSEQDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDAD 5677
+ + S T+ + E VSE+ + VE S+ + VE A
Sbjct: 1067 VVDEKVSVTEEVIEEEKSVSEEVLEEGSATEEVVEEGSCTEIVVEKGSDTEIVVEEGSA- 1125
Query: 5678 NTLSSQLVSETKEEHKLQAGEILPTEIIPRESS-DEALVSMLASREDDKV--ALQEDNCA 5848
+++V E E TE++ E S E ++ S ++ V L DN
Sbjct: 1126 ----TEIVVE----------EGSATEVVVEEGSVSEEMLEEEGSATEEVVEEGLSSDNVQ 1171
Query: 5849 DDVRETNDIQEERSISVETEESVGETKPKEHEDEIRDAHV--ETPTAPIILEENDSETLI 6022
++ E S+ +ES+ E P E + D + PT + +E+ +SE +I
Sbjct: 1172 KSKGVIENVGEIYSVKTAKDESMNEKIPLEKSSFVDDESFKGQGPTDNVSVEDVNSEDII 1231
Query: 6023 AEAKKGNEEINETERTVALDHEEEFVNHEAPKLEETKDEKSQEIPETAKATETTIDQTLP 6202
E E E T + + E EK E E AK E I + +P
Sbjct: 1232 NEHTPLEETKIEELPTEYITTADIHTRGETETKYNLIYEKINEEVEKAKFQEEKITENIP 1291
Query: 6203 IG----TSQADQTPSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETVPKESFIE 6370
+ T Q PSL + + + T++++ + + + +P+ S E
Sbjct: 1292 VERESVTEDIVQEPSLAQEVEQK------------ESDTNEIEETKLANEKIIPEVSVTE 1339
Query: 6371 APVSMLASGEDEPVTPQEGDYAANTQEERHVSAETEEKVGETKPKESQAEGAEKSDDQV- 6547
V G D +E + E VSA E E E E E S +++
Sbjct: 1340 NVVE--KEGLDTEEVLEEDESITEEIVEEEVSACEEIVEEEESSSEEIVEEEESSSEEIV 1397
Query: 6548 -EDESTKKTDVEVAGLENDYPTEEAEHG-----DETYSTLPVVGIXXXXXXXXXXXRAIN 6709
E+ES+ + VE ++ EE E +E ST V+
Sbjct: 1398 EEEESSSEEIVEEEESSSEEIVEEEESSSEEIIEEVSSTEEVLEEEGSVTEEIVEEEVST 1457
Query: 6710 DSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDILE----AKRLHGDKSGEAEKIKEE 6877
++ + E +EE G + + + +I+E +++ D E+I +E
Sbjct: 1458 TEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEKVLEDVGSNVEEIVQE 1517
Query: 6878 SGLAGKSLPIEEINLXXXXXXXXXXXXXTREIAQVL--PREEILISSSPLSAE-EQEHVI 7048
G + + EE++ T EI + + EEI++ S E +E +
Sbjct: 1518 EGPVAQEIVHEEVS--TTEKHDEVDRSTTEEIVEKVGSVSEEIIVEEVSASEEIVEEGSV 1575
Query: 7049 SDEKQEEREPQQDFNGSTSEKISLQVEHLKDFETSKKEQKDETHETVXXXXXXXXXXXXX 7228
++E EE + + + S + + + D E ++ E +
Sbjct: 1576 TEEVVEEEKLINEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEIL------------- 1622
Query: 7229 XXXXXXXXXSSEVKKDNKDARELEVGNDFVSRDGEKEEVPHNALENEEEMNEVVASEKQI 7408
V + E+ F E+E V A++ E + E + E+ I
Sbjct: 1623 ---EKESIVEEIVGPEGSVTEEIVDYGSFAEEVKEEELVTEEAVQYEGSVTEEIKEEESI 1679
Query: 7409 SDPVGVIKKA-SEAEHEDPVDDIKSNDDRDFPTEQAPKDQS--DEVSADE-TVPKEAIGE 7576
++ + + A +E E ++ + + TE+ + S DEV +E V ++ +GE
Sbjct: 1680 TENEAIEESAFAEIIEEKGPNNDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIVGE 1739
Query: 7577 ELKVPSSKVLDDIQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQVEETSFEFNKAQE 7756
E V V +++ ++ + V A +++E + H+ E + + A+E
Sbjct: 1740 ERSVTEKPV--EVERSATEDLVEEGA-------SVTEKVSVHE--GSTTEQILDESVAEE 1788
Query: 7757 DKKEE-TVDALITNVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQEDIGTYVKVQVP 7933
+EE +VD I +V + E + IE+ + E+E ++ ++E++
Sbjct: 1789 IVEEEVSVDDKIIEEEVSVDEVVEEEGSVIEEIVEEEESVPEEI--LEEELS-------G 1839
Query: 7934 DDEIKGDGHDSVAAQKEETSSIEEKREVEHVKAEMEDAIKHEVSVEEKNNTSENIDHEAA 8113
+E+ D + A +E S IEE E+ + E +I E + E + +E I E
Sbjct: 1840 SEEVLEDEWVTDAFMGQEGSVIEEIEEI----VDGEGSITEE--IVEDGSANEKIVEEEP 1893
Query: 8114 KEIEQEEGKQTNIVXXXXXXXXXXXNQESFNNVKETDD---AIDKTQPEIRDIESLSSVS 8284
+E+ GK+ ++ E V E + AI++ + E+++ ES+S
Sbjct: 1894 SRVEEVLGKEGFVIEEIIEEGSVIEQVEDTKTVSEKSEESSAIEEVK-EVKEEESIS--E 1950
Query: 8285 KTQDKPEPEYEVPNQQKREITNEV 8356
K +K E E +Q+ T ++
Sbjct: 1951 KIVEKEESVTEEIVRQEESTTEKI 1974
Score = 153 bits (386), Expect = 5e-35
Identities = 350/1615 (21%), Positives = 626/1615 (38%), Gaps = 145/1615 (8%)
Frame = +2
Query: 3725 EETTAHESESLKGDNHQEKNAEPVEATQNLD-DAEQISREVTVDTEREADITEKIEKV-Q 3898
EE E ++ +N E+ E A +++ D E ++ E+TVD + + +IE V +
Sbjct: 245 EEENVSEEIPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNE 304
Query: 3899 EGPTVIETPTIQ--------GEDIESETSLELKEEVDQSSKDTEEHEHVLERDIPQCETL 4054
E P ET T Q E+I E EE + + + E E V+ DIP+ + +
Sbjct: 305 EMPVEDETLTEQISSEHERVPEEIIEEKPFTEGEETESLTDEIVE-EGVVTDDIPEEQII 363
Query: 4055 -----KAEAVDTSTVEEAAIL--KTLETNISEPEAMHSETSLDLKVDKEQKEAETVKTVI 4213
+ E T + E I+ K E + S E + E D+ +K Q+E E+ I
Sbjct: 364 TEKVQEEEEFVTGELSEEDIINEKVQEEDESVTEELPEE---DIINEKVQEEEESAYQEI 420
Query: 4214 FSNEVGTSDAQAEEFGEHTEPCSSEIKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLDV 4393
+ T D E+ E + +++D+ +G EE+ V
Sbjct: 421 VQDGSVTKDV------EYKELVNDDVRDKENFVIEEDPFKGQLINEGLPVEEEFVTKELP 474
Query: 4394 QSGES--EKYQENEPDISLVSKTENGDKF---EEIPSVVEGAGLDETTHNQTLLDVESVV 4558
ES E+ E + ++ E F +EI SV E +E + N+ +VE V
Sbjct: 475 VKEESVFEELTEEDQSVTKEIPVEEHSVFKEVDEIESVTEEIVEEEGSVNE---EVEEEV 531
Query: 4559 KQSLDTPSEEETSXXXXXXXXXXXXXXVTLHQEGREEGSYGLDTKDEAVSVLESRELGEQ 4738
S + +ET L +EG + E V V E E+
Sbjct: 532 SVSGEV---DETEYVTEEVEETELVNEEVLKEEG---------SASEKV-VKEEGSASEK 578
Query: 4739 PQQEELCLANEQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGP 4918
+EE + E +E ++EE E + EE+ D+ S EE S+E I S+ E
Sbjct: 579 IVEEEGSVTEETASEEIVEEEGSVTEESSSEEIVEDEGSVTEESSSEEIVEEEGSVIEES 638
Query: 4919 EYETVVEAEKIGEEQVADKIQKSFETGEIVEAHSSLPSS---SEEKEHETVSE------- 5068
E +VE E +++ + ++ T E+VE ++ +E E E +++
Sbjct: 639 ASEVIVEDEVSASKEIVE--DEASVTEEVVEEEGAVSDEVQVTESVEDEIINQGIVDEVI 696
Query: 5069 -----KTDDEKVKDAEPIGD---MRERGLDIAETTH----------LSLPSVDQKEDVDE 5194
DE VK+ E + + + E ++ E T + +V++K+ +DE
Sbjct: 697 VEQEASVTDEIVKEDESVIEEIAVEETVTEVVEETKPMDEEIVDQGSVVENVEEKKTMDE 756
Query: 5195 IHIPSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSPMLSEKNDNETQTSKTS 5374
+ ++ + +EK T E+ + S AE + +E V N++ + + +
Sbjct: 757 EIVDQGSVVENVEEKKTMDEEIGDQGSVAEKVEEEELVTEEVIEREGSINEDIVKEASIT 816
Query: 5375 EDVCMQQEESGTLEVPKPEE-SKEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSEL 5551
E+V +Q E T +V K E + E K Q ++ + S D +
Sbjct: 817 EEV--EQIEPVTGKVEKIESITDEIKEQLVPEDIKEEQLDFEEIVAQRASVNDEKVEVAS 874
Query: 5552 VSEQDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDADNTLSSQLVSETKEEHKLQ 5731
++E+ ++ + ++ SE L E S + + +E E +
Sbjct: 875 ITEEVEE-----------------EEKSVSEEVLEEEGSTTEKVVEEGSSTEVVVEEQGS 917
Query: 5732 AGEILPTEIIPRE-SSDEALVSMLASREDDKVALQEDNCADDVRETNDIQEERSISVETE 5908
E E++ E S+ E +V S ++ L+E++ + + E + V+ E
Sbjct: 918 VSE----EVLEEEGSTTEEVVEEQGSVTEN--LLEEESASQGIVEKEEF-------VDEE 964
Query: 5909 ESVGETKPKEHEDEIRDAHVETPTAPIILEENDSETLIAEAKKGNEEINETERTVALDHE 6088
+SV + E E + + VE +I E+N+ E LI E + + +NE L E
Sbjct: 965 DSVKDQNVFEKEGSVTEQLVEEEKG-LINEDNEKEELITEMSEEIKSVNEEIEETDLSTE 1023
Query: 6089 E----------EFVNHEAPKLEETKDEKS--QEIPETAKATETTIDQTLPIGTSQADQTP 6232
E EFV E ++ +E+S +E+ ET +T+ +D+ + + ++
Sbjct: 1024 EIIKQQGLATYEFVEEEKSLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVIEEEK 1083
Query: 6233 SLVSD--KDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETVPKESFIE----APVSMLAS 6394
S+ + ++ ++V K +I E E +E V +
Sbjct: 1084 SVSEEVLEEGSATEEVVEEGSCTEIVVEKGSDTEIVVEEGSATEIVVEEGSATEVVVEEG 1143
Query: 6395 GEDEPVTPQEGDYAANTQEERHVSAETE------EKVGE-----TKPKESQAE--GAEKS 6535
E + +EG EE S + E VGE T ES E EKS
Sbjct: 1144 SVSEEMLEEEGSATEEVVEEGLSSDNVQKSKGVIENVGEIYSVKTAKDESMNEKIPLEKS 1203
Query: 6536 DDQVEDESTK----KTDVEVAGLENDYPTEEAEHGDET-YSTLPVVGIXXXXXXXXXXXR 6700
V+DES K +V V + ++ E +ET LP I
Sbjct: 1204 -SFVDDESFKGQGPTDNVSVEDVNSEDIINEHTPLEETKIEELPTEYITTADIHTRGETE 1262
Query: 6701 AINDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDILEAKRLHGD---KSGEAEKIK 6871
+ +++ E A +E+K + + + DI++ L + K + +I+
Sbjct: 1263 TKYNLIYEKINEEVEKAKFQEEKITENIPVERESVTEDIVQEPSLAQEVEQKESDTNEIE 1322
Query: 6872 EESGLAGKSLP---IEEINLXXXXXXXXXXXXXTREIAQVLPREEILISSSPLSAEE--Q 7036
E K +P + E + I + + EE+ + EE
Sbjct: 1323 ETKLANEKIIPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEEEVSACEEIVEEEESSS 1382
Query: 7037 EHVISDEKQEEREPQQDFNGSTSEKISLQVEHLKDFETSKKEQKDETHETVXXXXXXXXX 7216
E ++ +E+ E ++ S+ E + + ++ ++ +E E V
Sbjct: 1383 EEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIIEEVSSTEEVLEE 1442
Query: 7217 XXXXXXXXXXXXXSS--EVKKDNKDAREL--EVG---NDFVSRDGEK-EEVPHNALENEE 7372
S+ EVK + E+ E G +FV + G EE+ E+
Sbjct: 1443 EGSVTEEIVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEK 1502
Query: 7373 EMNEVVASEKQISDPVGVIKKASEAEHEDPVDDIKSNDDRDFPTEQAPKDQ----SDEVS 7540
+ +V ++ ++I G + A E HE+ V + +D+ D T + ++ S+E+
Sbjct: 1503 VLEDVGSNVEEIVQEEGPV--AQEIVHEE-VSTTEKHDEVDRSTTEEIVEKVGSVSEEII 1559
Query: 7541 ADETVPKEAIGEELKVPSSKVLDD--IQENSNTEAVTNFADRDLPVQNLSELIQSHQSPN 7714
+E E I EE V V ++ I E TE+VT + V + E++ S N
Sbjct: 1560 VEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQK-EVSDAEEVLGQEGSMN 1618
Query: 7715 Q------------------VEETSFEFNKAQEDKKEE---TVDALITNVQVQDQPKED-- 7825
+ V E ++ E+ KEE T +A+ V ++ KE+
Sbjct: 1619 EEILEKESIVEEIVGPEGSVTEEIVDYGSFAEEVKEEELVTEEAVQYEGSVTEEIKEEES 1678
Query: 7826 -FEAAAIEK----EISEQEHKLNDLTDVQEDIGT---YVKVQVPDDEIKGDGHDSVAAQK 7981
E AIE+ EI E++ ND +E + T +V V D+ I+ + +
Sbjct: 1679 ITENEAIEESAFAEIIEEKGPNNDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIVG 1738
Query: 7982 EETSSIEEKREVEHVKAE--MED--AIKHEVSVEEKNNTSENIDHEAAKEIEQEE 8134
EE S E+ EVE E +E+ ++ +VSV E + T + +D A+EI +EE
Sbjct: 1739 EERSVTEKPVEVERSATEDLVEEGASVTEKVSVHEGSTTEQILDESVAEEIVEEE 1793
Score = 150 bits (379), Expect = 3e-34
Identities = 328/1577 (20%), Positives = 618/1577 (38%), Gaps = 112/1577 (7%)
Frame = +2
Query: 3938 EDIESETSLELKEEVDQSSKDTEEHEHVLERDIPQCETLKAEAVDTSTVEEAAILKTLET 4117
ED+E E++ +K+TE+ E + Q + L E TLE
Sbjct: 17 EDMEETEKENEIEKIMDENKETEQTEEGNTEEFVQEKELNQE--------------TLEN 62
Query: 4118 NISEPEAMHSETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEI-K 4294
I E + ++K + E ++ + N +G + + EEF + P ++ K
Sbjct: 63 EIIVDHIKEEEDTRNVKEQESVLEESPIEELPVENNIGKINEEVEEFILNEIPLEEQVPK 122
Query: 4295 DESQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQSGE--SEKYQENEPDISLVSKTENGD 4468
+ Q + SSEE V D G+ +E+ E +S E
Sbjct: 123 ELPQEEIEEIVVEELPIDEHLSSEETTVTEEDTFKGQLINEEKPVEEKSVSEEIPVEEKS 182
Query: 4469 KFEEIP----SVVEGAGLDETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXXXXX 4636
EEIP SV E ++E ++ + E V + + P EE+
Sbjct: 183 VSEEIPVEEKSVSEEIPVEEKNVSEEIPVEEKNVSEEI--PVEEKNVSEEIPVEEENVSE 240
Query: 4637 XVTLHQEGREEGSYGLDTKDEAVS--------VLESRELGEQPQQEELCLANEQENETKL 4792
+ + +E E + ++E VS +E + E+ EE+ + + ++
Sbjct: 241 EIPVEEENVSE---EIPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPN 297
Query: 4793 QEEQVDKHEPTKEEVSNDQ-QSPVEEISNEVIQVSSASLSEGPEYETV--------VEAE 4945
+ E V++ P ++E +Q S E + E+I+ +EG E E++ V +
Sbjct: 298 EIETVNEEMPVEDETLTEQISSEHERVPEEIIE--EKPFTEGEETESLTDEIVEEGVVTD 355
Query: 4946 KIGEEQ-VADKIQ--KSFETGEIVEAHSSLPSSSEEKEHETVSEKTDD-----EKVKDAE 5101
I EEQ + +K+Q + F TGE+ E + + ++E E+V+E+ + EKV++ E
Sbjct: 356 DIPEEQIITEKVQEEEEFVTGELSE--EDIINEKVQEEDESVTEELPEEDIINEKVQEEE 413
Query: 5102 PIG--DMRERGLDIAETTHLSLPSVDQK--------EDVDEIHIPSVALPLDEQ------ 5233
++ + G + + L + D + ED + + + LP++E+
Sbjct: 414 ESAYQEIVQDGSVTKDVEYKELVNDDVRDKENFVIEEDPFKGQLINEGLPVEEEFVTKEL 473
Query: 5234 --------EKVTSTEKGETKSSEAEDD---KPDEHVDSSTSPMLSEKND-NETQTSKTSE 5377
E++T ++ TK E+ K + ++S T ++ E+ NE + S
Sbjct: 474 PVKEESVFEELTEEDQSVTKEIPVEEHSVFKEVDEIESVTEEIVEEEGSVNEEVEEEVSV 533
Query: 5378 DVCMQQEESGTLEVPKP----EESKEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSS 5545
+ + E T EV + EE +++ ++ + E S T+ T S
Sbjct: 534 SGEVDETEYVTEEVEETELVNEEVLKEEGSASEKVVKEEGSASEKIVEEEGSVTEETASE 593
Query: 5546 ELVSEQDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDADNTLSSQLV-SETKEEH 5722
E+V E+ + + E++SE + E S + + S +V E
Sbjct: 594 EIVEEEGSVTEESSSEEIVEDEGSVTE-ESSSEEIVEEEGSVIEESASEVIVEDEVSASK 652
Query: 5723 KLQAGEILPTEIIPRES---SDEALVSMLASRE-------DDKVALQEDNCADD-VRETN 5869
++ E TE + E SDE V+ E D+ + QE + D+ V+E
Sbjct: 653 EIVEDEASVTEEVVEEEGAVSDEVQVTESVEDEIINQGIVDEVIVEQEASVTDEIVKEDE 712
Query: 5870 DIQEERSISVETEESVGETKPKEHEDEIRDAHVETPTAPIILEEN--DSETL---IAEAK 6034
+ EE ++ E V ETKP + E + + VE ++E D ++ + E K
Sbjct: 713 SVIEEIAVEETVTEVVEETKPMDEEIVDQGSVVENVEEKKTMDEEIVDQGSVVENVEEKK 772
Query: 6035 KGNEEINETERTVALDHEEEFVNHEAPKLEETKDEKSQEIPETAKATETTIDQTLPIGTS 6214
+EEI + EEE V E + E + +E +I + A TE ++Q P+ T
Sbjct: 773 TMDEEIGDQGSVAEKVEEEELVTEEVIEREGSINE---DIVKEASITE-EVEQIEPV-TG 827
Query: 6215 QADQTPSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETVPKESFIEAPVSMLAS 6394
+ ++ S+ + +Q + ++ E + E V + + + +AS
Sbjct: 828 KVEKIESITDEIKEQLVPE-------------DIKEEQLDFEEIVAQRASVNDEKVEVAS 874
Query: 6395 GEDEPVTPQEGDYAANTQEERHVSAETEEKVGETKPKESQAEGAEKSDDQVEDESTKKTD 6574
+E +EE+ VS E E+ G T E E ++ VE++ + +
Sbjct: 875 ITEEV-----------EEEEKSVSEEVLEEEGST--TEKVVEEGSSTEVVVEEQGSVSEE 921
Query: 6575 VEVAGLENDYPTEE---AEHGDETYSTLPVVGIXXXXXXXXXXXRAINDSASSEVSMIKE 6745
V LE + T E E G T + L +SAS + +E
Sbjct: 922 V----LEEEGSTTEEVVEEQGSVTENLLE------------------EESASQGIVEKEE 959
Query: 6746 PADQEEKKGDDVVESNEKDFVSDILEAKRLHGDKSGEAEKIKEESGLAGKSL--PIEEIN 6919
D+E+ D V E ++E ++ ++ E E++ E KS+ IEE +
Sbjct: 960 FVDEEDSVKDQNVFEKEGSVTEQLVEEEKGLINEDNEKEELITEMSEEIKSVNEEIEETD 1019
Query: 6920 LXXXXXXXXXXXXXTREI--AQVLPREEILISSSPLSAE--EQEHVISDEKQEEREPQQD 7087
L T EI Q L E + L+ + E+E V + + E Q+
Sbjct: 1020 L------------STEEIIKQQGLATYEFVEEEKSLTDKLLEEESVTKEVGETELSTQE- 1066
Query: 7088 FNGSTSEKISLQVEHLKDFETSKKEQKDE---THETVXXXXXXXXXXXXXXXXXXXXXXS 7258
EK+S+ E +++ ++ +E +E T E V
Sbjct: 1067 ---VVDEKVSVTEEVIEEEKSVSEEVLEEGSATEEVVEEGSCTEIVVEKGSDTEIVVEEG 1123
Query: 7259 S--EVKKDNKDARELEVGNDFVSRDGEKEEVPHNALENEEEM-NEVVASEKQISDPVGVI 7429
S E+ + A E+ V VS + +EE EE + ++ V K + + VG I
Sbjct: 1124 SATEIVVEEGSATEVVVEEGSVSEEMLEEEGSATEEVVEEGLSSDNVQKSKGVIENVGEI 1183
Query: 7430 KKASEAEHED-----PVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPKEAIGEELKVPS 7594
A+ E P++ DD F Q P +D VS ++ ++ I E +
Sbjct: 1184 YSVKTAKDESMNEKIPLEKSSFVDDESF-KGQGP---TDNVSVEDVNSEDIINEHTPLEE 1239
Query: 7595 SKVLDDIQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQVEETSFEFNKAQEDKKEET 7774
+K+ + E T + + + + E I +VE+ F QE+K E
Sbjct: 1240 TKIEELPTEYITTADIHTRGETETKYNLIYEKIN-----EEVEKAKF-----QEEKITEN 1289
Query: 7775 VDALITNVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQ-EDIGTYVKVQVPDDEIKG 7951
+ V+ + ++ + ++ +E+ ++E N++ + + + +V V ++ ++
Sbjct: 1290 IP-----VERESVTEDIVQEPSLAQEVEQKESDTNEIEETKLANEKIIPEVSVTENVVEK 1344
Query: 7952 DGHDSVAAQKEETSSIEEKREVEHVKA-----EMEDAIKHEVSVEEKNNTSENIDHEAAK 8116
+G D+ +E+ S EE E E V A E E++ E+ EE++++ E ++ E +
Sbjct: 1345 EGLDTEEVLEEDESITEEIVE-EEVSACEEIVEEEESSSEEIVEEEESSSEEIVEEEESS 1403
Query: 8117 E---IEQEEGKQTNIVXXXXXXXXXXXNQESFNNVKETDDAIDKTQPEIRDI--ESLSSV 8281
+E+EE IV ++E V T++ +++ +I E +S+
Sbjct: 1404 SEEIVEEEESSSEEIV-----EEEESSSEEIIEEVSSTEEVLEEEGSVTEEIVEEEVSTT 1458
Query: 8282 SKTQDKPEPEYEVPNQQ 8332
+ +D EV ++
Sbjct: 1459 EEVKDIGSVSEEVLEEE 1475
Score = 132 bits (332), Expect = 1e-28
Identities = 343/1612 (21%), Positives = 616/1612 (37%), Gaps = 56/1612 (3%)
Frame = +2
Query: 341 REPQSLNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQEED 520
+E S+NE+ +E+ ++ LE EE S + ++EE+ + + LE+E
Sbjct: 3453 KEENSVNEEVLEEEGSYTEEILE-----------EEGSYTEEILEEEGSFTEEILEEE-- 3499
Query: 521 IGNISKVLTDTTPVKVDEYDIEKSLN-SVCEEIPIKTDEVREETDSRTVETSVNGTEAEH 697
G+ ++ + + E S N + EE T+E+ EE S T G++ E
Sbjct: 3500 -GSYNEEILEE----------EGSYNEEILEEEGSFTEEILEEEGSATDYFVGQGSDNEE 3548
Query: 698 NATVSVEEISRN----GDNTVNETVSEDQTATDGEPLHDVETIKREAE--PFYKTVVEDA 859
+EE S G ++ E V E++ D E + + E E E + VVE+
Sbjct: 3549 ----IIEEGSATDYFVGQGSIIEEVLEEE-GLDTEKVFENEGSATEFEETESFTEVVEET 3603
Query: 860 KIVN---TEETTAHESKILKEDNHQEEYAESV--EATKNSDAAEQSSREVTVDKE--KEE 1018
+ VN EET+ +E + K ++ E+ E + E K + +E +D E KEE
Sbjct: 3604 ESVNENILEETSINE--VQKIESITEDIKEQLVPEEIKEEQLDSEEIKEEQLDSEEIKEE 3661
Query: 1019 DI-IQNIEEVQESPSVMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVP 1195
+ + I+E Q P ++ + E+I+ + + E + +++ + ++E + ++
Sbjct: 3662 QLDSEEIKEEQLVPEEIKEEQLDSEEIKEEQLVPEEIKEEQLNSEEIKEEQLDSEEI--- 3718
Query: 1196 QSETLVTEAKTAETFSVQEAEILKTNINESEAHSAIGGEEDGQETKENTEPSKDLKDD-- 1369
+ E L +E E +E + K ++NE EE+G T+E E + + ++
Sbjct: 3719 KEEQLDSEEIKEEQLDSEEIKEQKGSVNEEVV------EEEGSVTEEIKEQEESVNEEVL 3772
Query: 1370 KEQEDSETVKTIISSDEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETG-- 1543
+E E++E++K I + + ++ E E + E+ ++ E + TG
Sbjct: 3773 EEVEETESIKEEIVEGGIATQEIIEE------ESDTKEVVEEEVIDSEKLVDAGSVTGEV 3826
Query: 1544 -PEIETAVDGESVHEIETTERVLLEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXX 1720
PE E +V E V E TTE VL E ++ + T
Sbjct: 3827 MPE-EVSVTDEVVEEGSTTEEVLEEQKSVNEEVVEDGLTIDDFVGLQGSTT--------- 3876
Query: 1721 XXXXXXXXTSVHESESLKENAEPVEAV-KNSDGTEQI-SREVTVDRAKEEDIAPKTEEIQ 1894
E ++E+ +E + + TE+I ++V+V EDI K +
Sbjct: 3877 -------------EEVVEEDGSAIEKILEEETATEEIVEKQVSV----TEDIVEKEGSVN 3919
Query: 1895 ERPSESKASLEPKEEVDHISNETEEHEHVLERDVQQCETIESEAVETKEDTQPSLDLKED 2074
E E + E + + E E +V E + S +E +E+ + ++ E+
Sbjct: 3920 EEIIEEASVAEEIIQGGSFTEEIVGQEESATEEVIDEEGLISNEIEEEEEKSVTEEMIEE 3979
Query: 2075 KETEEAETFKTVFSSDEVRSSAVQEEQFGEHTEPCSSEIKDESHGKEESV--EVKS--QE 2242
E V DEV +V EE E E EI E E V EV+S E
Sbjct: 3980 VE--------EVSVDDEVEEVSVAEEIVEE--ELVDDEILPEELSATEDVIEEVRSVTDE 4029
Query: 2243 TVQDENTEDKHDVLKVPSTESEKYQGNEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELN 2422
VQ+E+ + ++L+ + SE+Y ++ S T + E+S V N E +
Sbjct: 4030 IVQEESVCE--EILEQEVSASEEYVDDK------SVTDDFVGHERSVIQDVENT--ESVT 4079
Query: 2423 DEKINVDQVDGTQIMEEPIGLDSNGAEAEQIDQNITNETEEILVAKPVSLLDVKSVEQMQ 2602
+E VD+ ++EE + + G+ E+I + +TEE+L K V+ DV VEQ
Sbjct: 4080 EEIAEVDK----SVIEEAV--EKQGSVTEEIVEEEELDTEEVLEDKSVT-GDV--VEQEG 4130
Query: 2603 KPKLESPSEVSEETSKTVDXXXXXXXXXXVTLYQEGQVDGSYGLET-KEETVSVXXXXXX 2779
K E SE E ++ VD T Y +++ E E+ +S+
Sbjct: 4131 SGKDE--SEAKESFTEEVDELKSVKEEDQETEYISREIEEESATEQHSEQELSI------ 4182
Query: 2780 XXXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKIEEKTDSIELGEIAQEERSVTD 2959
+ V++ L K K+ ++I E+T S+ EI +EER +
Sbjct: 4183 ------NKEVVETESLTK---------DIEEEKSTTQEILEETQSVN-EEIVEEERDTDE 4226
Query: 2960 LTPLQEESSQPNEQEKETKLEKHEPTNEEVKSDEVIEV--LSASPSKELEGETVVXXXXX 3133
+ L+E+ S E +E E E +DE++EV L KE EG
Sbjct: 4227 V--LKEKVSPSEEVIEEQASTTEEFLEERSSTDEIVEVEDLFTEEVKEREGSVTEEIVEE 4284
Query: 3134 XXXXXXXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVAEEIVDEKAKEEVPMLQ 3313
LE ++ ++ EEI+ EE Q
Sbjct: 4285 GSDTGEIVEEEGSDAEEILE--------EGSFNEEIVEEEGSITEEILQGSVTEEFVGQQ 4336
Query: 3314 ---IKNEDDATKIHETRVE-----QARDIGPSLTEICSINQNQPEEQVKEACSKEEQEKE 3469
I+ + E RVE + D S+TE+ EE+V + E E
Sbjct: 4337 GSVIEEIVETESAIEERVEDESATEEVDERESVTEVV-------EEEVSSSDEVVEGSIE 4389
Query: 3470 ISTNSENIVNETYALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXP 3649
+E V E H V +++VE T+S
Sbjct: 4390 EVIENEGSVTEEILEHEVSADENFVGQAVSVIEEVEGTES-------------------- 4429
Query: 3650 RLDAIXXXXXXXXXXXXQDAKIVNNEETTAHESESLKGDNHQEKNA---EPVEATQNLDD 3820
+ ++ V+ E +++S+ ++ ++K E ++ + DD
Sbjct: 4430 ----VTEEVVEETESVSEEIVEVSPTENVVQQTDSVIEEDVEQKEGSFNEEIDIRELGDD 4485
Query: 3821 AEQISREVTVDTEREADITEKIEKVQEGPTVIETPTIQGEDIESETSLELKEEVDQSSKD 4000
+ ERE TE++ + T + D+E +S E +EEV +
Sbjct: 4486 GVE---------EREKISTEEVVGQDKSATGDVEESSSTGDVEEVSSTEDEEEVSSTEGL 4536
Query: 4001 TEEHEHVLERDIPQCETLKAEAVDTSTVEEAAILKTLETNISEPEAMHSETSL--DLKVD 4174
E ++ E ++ E T VEE ++ + N+ E +++ E S+ D+ D
Sbjct: 4537 EEVSSTEGLEEVSNTEDVE-EVSSTEDVEEGSVAE----NVKETKSITEEVSVEEDIITD 4591
Query: 4175 KEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDESQGXXXXXXXXXXXTVQG 4354
K E E + ++A EE P EI E
Sbjct: 4592 KVSVEQEVM-----------AEASVEENILTEVPVEEEIMTEKL---------------- 4624
Query: 4355 ESSEEKDVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEEIPSVV----EGAGLDETT 4522
S E+K +N EK E + E+G+ E +P+ V E G++ETT
Sbjct: 4625 -SVEDKALN---------EKIMSEEEIV-----IEDGNVHEVVPAEVSVTEEIPGVEETT 4669
Query: 4523 HNQTLLDVESVVKQSL--DTPSEEETSXXXXXXXXXXXXXXVTLHQEGREEGSYGLDTKD 4696
+N++ + E+VV + + D +E + + S+ + +
Sbjct: 4670 NNESHVKGENVVNEVVVDDNSVNDEIQFDDDSSIEIYTVDSKDVFHKEENYDSFREEVRS 4729
Query: 4697 EA---VSVLESRELGEQPQQEELCLANEQENETKLQE--EQVDKHEPTKEEVSNDQQSPV 4861
+ +S ++ ++ + E+ + + T + E+V H KE V+ + V
Sbjct: 4730 DENIHISRKKNENFVKKIENEKSSVGHVPTEYTSKENIAEEVPSHIMFKENVTEEVPKEV 4789
Query: 4862 EEISNEVIQVSSASLSEGPEYETVVE---AEKIGEEQVADKIQKSFETGEIV 5008
+ N V +V E E ++E + EE + +++ + + EIV
Sbjct: 4790 KYEENTVEEV----FEEVTSKENIIEEAPGDINSEENIIEEVPEVVTSEEIV 4837
Score = 36.6 bits (83), Expect = 7.3
Identities = 52/252 (20%), Positives = 110/252 (43%), Gaps = 3/252 (1%)
Frame = +2
Query: 542 LTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDSRTVETSVNGTEAEHNATVSVEE 721
L++ T +K D KS N + IK + + T R V+T N +N+
Sbjct: 4910 LSEDTLMKFYGSDSNKSANDNDTVMVIKILKDKWGT-GRIVDTIANSLNKSYNSLYHNLY 4968
Query: 722 ISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNTEETTAHESK 901
I D +N+T +T H + + E ++K D KI + +ES
Sbjct: 4969 IEMEKDLLINKT----ETFNKWSKQHWNKLDNWKEEKWFKLFKRDLKI---DMRNTYESD 5021
Query: 902 ILKEDNHQEEYAE-SVEATKNSDAAEQSSREVTVDKEKE-EDIIQNIEEVQESPSVMESP 1075
+E+N++E E S E KN+ + + + T++K KE ++ +++ +++ + +S
Sbjct: 5022 QNEEENNEESMNELSDELIKNNTSDNMRNEQKTLEKNKEYSNLSKDLGLIEKQKIIWKSW 5081
Query: 1076 TIQG-EDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAKTAETFSVQE 1252
++ +IE+ + + K+ + +VL + E +++ V++
Sbjct: 5082 IVKNVNNIENWFDEMWFKNVVNELKEKNDVSNVLQENASEASVENYISD--------VED 5133
Query: 1253 AEILKTNINESE 1288
++ + +IN+SE
Sbjct: 5134 SKDMTNSINDSE 5145
>ref|NP_701352.1| antigen 332, putative [Plasmodium falciparum
3D7]|gi|23496420|gb|AAN36076.1|AE014843_40 antigen 332,
putative [Plasmodium falciparum 3D7]
Length = 5507
Score = 269 bits (687), Expect = 7e-70
Identities = 587/2816 (20%), Positives = 1049/2816 (36%), Gaps = 248/2816 (8%)
Frame = +2
Query: 443 EEVSVEKPVIEE-DQTEAKHSLEQEEDIGNISKVLTDTTPVKVDEYDIEKSLNSVCEEIP 619
EE EK IE+ ++TE ++ +E+ I + +K T +E+ EK LN E
Sbjct: 7 EEFPKEKYNIEDMEETEKENEIEK---IMDENKETEQTEEGNTEEFVQEKELNQETLENE 63
Query: 620 IKTDEVREETDSRTV--------ETSVNGTEAEHNATVSVEEISRNGDNTVNETVSEDQT 775
I D ++EE D+R V E+ + E+N EE+ + +NE E+Q
Sbjct: 64 IIVDHIKEEEDTRNVKEQESVLEESPIEELPVENNIGKINEEVE---EFILNEIPLEEQV 120
Query: 776 ATD----------------GEPLHDVETIKREAEPFYKTVVEDAKIVN----TEETTAHE 895
+ E L ET E + F ++ + K V +EE E
Sbjct: 121 PKELPQEEIEEIVVEELPIDEHLSSEETTVTEEDTFKGQLINEEKPVEEKSVSEEIPVEE 180
Query: 896 SKILKEDNHQEE-YAESVEATKNSDAAEQSSREVTVDKE---KEEDIIQNI--------- 1036
+ +E +E+ +E + + S + E E V +E +E+++ + I
Sbjct: 181 KSVSEEIPVEEKSVSEEIPVEEKSVSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEKNVSE 240
Query: 1037 ----------EEVQESPSVMESPTIQGEDIESKASLDHE------EEMDKITKDTEEQEH 1168
EE+ E +E + E + + ++D + E++ + ++ ++
Sbjct: 241 EIPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEEMPVEDE 300
Query: 1169 VLVRDVP-----VPQ---SETLVTEAKTAE--TFSVQEAEILKTNINESEAHSAIGGEED 1318
L + VP+ E TE + E T + E ++ +I E + + EE+
Sbjct: 301 TLTEQISSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQEEE 360
Query: 1319 GQETKENTEPSKDLKDDKEQEDSETVKTIISSDEVRSSDVQAEVFGEHTE--PCSSEIKD 1492
T E +E +D+ ++K QE+ E+V + +++ + VQ E + E S KD
Sbjct: 361 EFVTGELSE--EDIINEKVQEEDESVTEELPEEDIINEKVQEEEESAYQEIVQDGSVTKD 418
Query: 1493 DRHGRDESIEVKAKETGPEIETAVDGESVHE-IETTERVLLEAXXXXXXXXXXXXXXPSL 1669
+ + +V+ KE E G+ ++E + E + +
Sbjct: 419 VEYKELVNDDVRDKENFVIEEDPFKGQLINEGLPVEEEFVTKELPVKEESVFEELTEEDQ 478
Query: 1670 NAIEKAETXXXXXXXXXXXXXXXXXTSVHESESLKENAEPVEAVKNS-DGTEQISREVTV 1846
+ ++ V E S+ E E +V D TE ++ EV
Sbjct: 479 SVTKEIPVEEHSVFKEVDEIESVTDEIVEEEGSVNEEVEEEVSVSGEVDETEYVTEEVEE 538
Query: 1847 DRAKEEDIAPKTEEIQER--PSESKASLEPKEEVDHISNETEEHEHVLERDVQQCETIES 2020
E++ + E+ E AS + EE ++ ET E V E E+
Sbjct: 539 TELVNEEVLKEEGSASEKVVKEEGSASEKIVEEEGSVTEETASEEIVEEEGSVTEESSSE 598
Query: 2021 EAVETK---EDTQPSLDLKEDKETEEAETFKTVFSSDEVRSS-------------AVQEE 2152
E VE + + S ++ E++ + E+ V DEV +S V+EE
Sbjct: 599 EIVEDEGSVTEESSSEEIVEEEGSVIEESASEVIVEDEVSASKEIVEDEASVTEEVVEEE 658
Query: 2153 QFGEHTEPCSSEIKDE--SHGKEESVEVKSQETVQDENTEDKHDVLKVPSTESEKYQGNE 2326
+ ++DE + G + V V+ + +V DE ++ V++ + E E
Sbjct: 659 GAVSDEVQVTESVEDEIINQGIVDEVIVEQEASVTDEIVKEDESVIEEIAVE-------E 711
Query: 2327 PETVLVSNTGSYEKSEKSPSDLVLNVDKEELNDEKI-----NVDQVDGTQIMEEPIGLDS 2491
T +V T ++ +V NV++++ DE+I V+ V+ + M+E IG
Sbjct: 712 TVTEVVEETKPMDEEIVDQGSVVENVEEKKTMDEEIVDQGSVVENVEEKKTMDEEIGDQG 771
Query: 2492 NGAEAEQIDQNITNE------------------TEEILVAKPVSLLDVKSVEQMQKPKLE 2617
+ AE + ++ +T E TEE+ +PV+ VE+++ E
Sbjct: 772 SVAEKVEEEELVTEEVIEREGSINEDIVKEASITEEVEQIEPVT----GKVEKIESITDE 827
Query: 2618 SPSEVSEETSKTVDXXXXXXXXXXVTLYQEGQVDGSYGLETKEETVSVXXXXXXXXXXXX 2797
++ E K ++ E S E +EE SV
Sbjct: 828 IKEQLVPEDIKEEQLDFEEIVAQRASVNDEKVEVASITEEVEEEEKSVSEEVLEEEGSTT 887
Query: 2798 XR----SVIDPTPLQKPTXXXXXXXXXXXXKTVDEKIE--EKTDSIELGEIAQEERSVTD 2959
+ S + ++ + + + EK E ++ DS++ + ++E SVT+
Sbjct: 888 EKVVKGSSTEVVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKEGSVTE 947
Query: 2960 -------------------LTPLQEESSQPNEQEKETKLEKHEPTNEE-VKSDEVIEVLS 3079
+T + EE NE+ +ET L E ++ + + E +E
Sbjct: 948 QLVEEEKGLINEDNEKEELITEMSEEIKSVNEEIEETDLSTEEIIKQQGLATYEFVEEEK 1007
Query: 3080 ASPSKELE--------GETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQTVXXXXXXXXX 3235
+ K LE GET + E V
Sbjct: 1008 SLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVIEEEKSVSEEVLEEGSATEEVVE 1067
Query: 3236 XXXQDHVTVAEEIVDEKAKEEVPMLQI---KNEDDATKIHETRVEQARDIGPSLTEICSI 3406
V V E E EE +I K D + E + S TE+
Sbjct: 1068 EGSCTEVVVEEGSCTEVVVEEGSCTEIVVEKGSDTEIVVEEGSATEIVVEEGSATEVVVE 1127
Query: 3407 NQNQPEEQVKEACSKEEQEKEISTNSENIVNETYALHSVXXXXXXXXXNGESLDDVETTK 3586
+ EE V+E EE +E + +E +V E + +V GE + V+T K
Sbjct: 1128 EGSATEEVVEEGSVSEEMLEEEGSATEEVVEEGLSSDNVQKSKGVIENVGE-IYSVKTAK 1186
Query: 3587 SXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQD--AKIVNNEETTAHESESLK 3760
D +D ++ + NE T E++ +
Sbjct: 1187 DESMNEKIPLEKSSFVD------DESFKGQGPTDNVSVEDVNSEDIINEHTPLEETKIEE 1240
Query: 3761 GDNHQEKNAE-----PVEATQNLDDAEQISREVTVDTEREADITEKIEKVQEGPTVIETP 3925
A+ E NL E+I+ EV +E ITE I +E T
Sbjct: 1241 LPTEYITTADIHTKGETETKYNL-IYEKINEEVEKAKFQEEKITENIPVERESVT----- 1294
Query: 3926 TIQGEDIESETSLELKEEVDQSSKDTEEHEHVL---ERDIPQC----ETLKAEAVDTSTV 4084
EDI E S L +EV+Q DT E E E+ IP+ ++ E +DT V
Sbjct: 1295 ----EDIVQEPS--LAQEVEQKESDTNEIEETKLANEKIIPEVSVTENVVEKEGLDTEEV 1348
Query: 4085 --EEAAILKTL---ETNISEPEAMHSETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQA 4249
E+ +I + + E + SE E+S + V++E+ +E + V ++ +
Sbjct: 1349 LEEDESITEEIVEEEVSSSEEIVEEEESSSEEIVEEEESSSEEI--------VEEEESSS 1400
Query: 4250 EEFGEHTEPCSSEIKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQSGESEKYQENE 4429
EE E E S EI +E + T E E++ ++ + E E
Sbjct: 1401 EEIVEEEESSSEEIVEEEESSSEEIIEEVSST---EEVLEEEGSVTEEIVEEEVSTTEEV 1457
Query: 4430 PDISLVSK---TENGDKFEEI----PSVVEGAGLDETTHNQTLLDVESVVKQSLDTPS-- 4582
DI VS+ E G EE SV+E E++ + L DV S V++ +
Sbjct: 1458 KDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEKVLEDVGSNVEEIVQEEGPV 1517
Query: 4583 -----EEETSXXXXXXXXXXXXXXVTLHQEGREEGSYGLDTKDEAVSVLESRELGEQPQQ 4747
EE S + + G ++ + ++E + E+ +
Sbjct: 1518 AQEIVHEEVSTTEKHDEVDRSTTEEIVEKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVE 1577
Query: 4748 EELCLANEQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGPEYE 4927
EE L NE + EE V K EEV + S EEI + V EG E
Sbjct: 1578 EEK-LINEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSVTE 1636
Query: 4928 TVVE----AEKIGEEQVADKIQKSFETGEIVEAHSSLPSSSEEKEHETVSEKTDDEKVKD 5095
+V+ AE++ EE++ + +E G + E + E+E + E E +++
Sbjct: 1637 EIVDHGSFAEEVKEEELVTEEAVQYE-GSVTE---EIKEEESITENEAIEESAFAEIIEE 1692
Query: 5096 AEPIGD--MRERGLDIAETTHLSLPSVDQKEDVDEIHIPSVALPLDEQEKVTSTEKGETK 5269
P D ++E GLD E + + + E+ ++ V EK E+ T+
Sbjct: 1693 KGPNTDEIVKEEGLDTEEIVNEVSVTDEVIEEEKLVNEQIVGEERSVTEKPVEVERSATE 1752
Query: 5270 SSEAED----DKPDEHVDSSTSPMLSEKNDNETQTSKTSEDVCMQQEESGTLEVPKPEES 5437
E+ +K H S+T +L E E + S D + +EE EV + E S
Sbjct: 1753 DLVEEEASVTEKVSVHEGSTTEQILDESVAEEIVEEEVSVDDKIIEEEVSVDEVVEEEGS 1812
Query: 5438 KEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSELVSEQDDQSPXXXXXXXXXXXXX 5617
++ ++ L E S ++ L E V++
Sbjct: 1813 VIEE------IVEEEESVPEEILEEELSGSEEVLEDEWVTD----------AFMGQEGSV 1856
Query: 5618 AHDVEATSERNLPVETSDADNTLSSQLVSETK------EEHKLQAGEILPTE-IIPRESS 5776
++E E D + +++ ++V + EE + E+L E + E
Sbjct: 1857 IEEIE---------EIVDGEGSITEEIVEDGSANEKIVEEEPSRVEEVLGKEGFVIEEII 1907
Query: 5777 DEALVSMLASREDDKVALQEDNCADDVRETNDIQEERSIS---VETEESVGETKPKEHED 5947
+E S++ ED K ++ + + E +++EE SIS VE EESV E ++ E
Sbjct: 1908 EEG--SVIEQVEDTKTVSEKSEESSAIEEVKEVKEEESISEKIVEKEESVTEEIVRQEES 1965
Query: 5948 EIRDAHVETPTAPIILEENDSET-LIAEAKKGNEEIN---ETERTVALDHEEEFVNHEAP 6115
+ +E+ DS T + E + N E+ E + + + +HE+E V+ A
Sbjct: 1966 TTEKIVKDVSPTEDFVEQTDSVTEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSVNAQ 2025
Query: 6116 KLEETKDEKSQEIPETAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTPKQVXXXXXXX 6295
E K ++EI + TE +++ + T D+T S+ + ++ V
Sbjct: 2026 VTYE-KKSVTKEIVDEVSRTEEIVEENGSV-TEGVDETGSVTEEIIEEA--TVTEEVVED 2081
Query: 6296 XXXTHKVQAEDIFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAET 6475
T +V + E V S E V S +E + +EG +EE VS E
Sbjct: 2082 GSVTEEVVEDGSVIQEVVEDGSVTEEIVQENGSVTEE-IVEEEGSVNEEVEEEVSVSGEV 2140
Query: 6476 EEKVGETKPKESQAEGAEKSDDQVEDESTKKTDVEVAGLENDYPTEEAEHGDETYSTLPV 6655
+E T+ E + E + VE+E + +V+ E +Y TEE E +E +
Sbjct: 2141 DETEYVTEEVEEEGSVVE---EIVEEEGSVSGEVD----ETEYVTEEVE--EEGSVVEEI 2191
Query: 6656 VGIXXXXXXXXXXXRAINDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDILE---- 6823
V + + E S+++E ++E G E +E ++V++ +E
Sbjct: 2192 VEEEGSVSGEVDETEYVTEEVEEEGSVVEEIVEEE---GSVSGEVDETEYVTEEVEEEGS 2248
Query: 6824 -AKRLHGDKSGEAEKIKEESGLAGKSLPIEEINLXXXXXXXXXXXXXTREI-AQVLPREE 6997
+ + ++ E+I EE G + + E+ T E+ QV +E
Sbjct: 2249 VVEEIVEEEGSVVEEIVEEEGSVSEVVDETEL----VNDEIVEQAPFTEEVEEQVSVNDE 2304
Query: 6998 ILISSSPLSAEEQEHVISDEKQEEREPQQDF-----------------NGSTSEKISLQV 7126
I+ +S A E+ I++ +E E ++ F +G +E+I +
Sbjct: 2305 IIEDASVAEAVEESESITESVSQEEETEKGFVIEKVEETGAVTEEIVQDGLITEEILEES 2364
Query: 7127 EHLKDFETSKKEQKDETHET--VXXXXXXXXXXXXXXXXXXXXXXSSEVKKDNKDAREL- 7297
E + +K+ +E ET + + EV++ EL
Sbjct: 2365 ESVNGEIINKESDAEEILETEFLTEEVVGQAGSTSEEIVEEEGSVTKEVEEKESVTEELV 2424
Query: 7298 ---EVGNDFVSRDGEKEEV-------PHNALENEEEMNEVVASEKQISDPVGVIKKASEA 7447
V + V EEV +E E E++ E + + V++K A
Sbjct: 2425 DEGSVTEELVDEGSVTEEVVEQGGSIAQEIVEEESATEEIIRDETNVEE---VLEKEGSA 2481
Query: 7448 EHEDPVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPKEAIGEELKVPSSKVLDDIQENS 7627
E D +ND + +E+S E E+LK +S + + ++E S
Sbjct: 2482 TEEIVQDGSGTNDFVGKQGSVIEEVVEEEISTTE--------EKLKEEASAIEEFVEEES 2533
Query: 7628 NTEAVTNFADRDLPVQNLSELIQSHQSPNQVEETSFEFNKAQEDKKEETVDALITNVQVQ 7807
E V + L +N+ +S E SF E+++ T + ++ V
Sbjct: 2534 IREDV---LEESLVTENVVGQQESVTEEIVDGEGSFT-EDIVEEEESVTEEIVVDEESVT 2589
Query: 7808 DQPKEDFEAAAIEKEISEQEHKLNDLTDVQEDIGTYVKVQVPDDEIKGDGHDS-VAAQKE 7984
+ ED E + +EI E E + ++ ED G++ + + + + + D+ A+KE
Sbjct: 2590 KEIVEDEE--LVTEEIVEDEGSFTE--EIVEDEGSFTEEVIEERSLIEEVEDTETVAEKE 2645
Query: 7985 ETSSIEEKREVEHVKAEMEDAIKHEVSVEEKNNTSENIDHEAAKE--IEQEEGKQT 8146
E S I +E+ K+ E ++ E SV E+ E++ E ++ + +EEG T
Sbjct: 2646 EGSVI---KEIIDEKSLTEKIVEEEKSVTEEVEEKESVKEEVEEQRLVVEEEGSAT 2698
Score = 258 bits (660), Expect = 9e-67
Identities = 634/2991 (21%), Positives = 1140/2991 (37%), Gaps = 310/2991 (10%)
Frame = +2
Query: 314 KMIKNLLSFREPQSLNEKKEDEKIILSDVTLENKK-EEDTTGKPEEVSVEKPVIEEDQTE 490
K + + E E +EK + ++ +E K E+ + + VS E PV E++ +E
Sbjct: 181 KSVSEEIPVEEKSVSEEIPVEEKSVSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEKNVSE 240
Query: 491 ----AKHSLEQE--------EDIGNISKVLTDTTPVKVDEYD-IEKSLNSVCEEIPIKTD 631
+ ++ +E ED+ + +T+ V YD + + +V EE+P++ +
Sbjct: 241 EIPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEEMPVEDE 300
Query: 632 EVREETDS---RTVETSVNG---TEAEHNATVSVEEISRNG--------DNTVNETVSED 769
+ E+ S R E + TE E +++ +EI G + + E V E+
Sbjct: 301 TLTEQISSEHERVPEEIIEEKPFTEGEETESLT-DEIVEEGVVTDDIPEEQIITEKVQEE 359
Query: 770 QTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNTEETTAHESKILKEDNHQEEYAESVE 949
+ GE L + + I + + ++V E+ EE +E +E++ +E +
Sbjct: 360 EEFVTGE-LSEEDIINEKVQEEDESVTEEL----PEEDIINEKVQEEEESAYQEIVQDGS 414
Query: 950 ATKNSDAAEQSSREVTVDKEKEEDIIQNIEEVQESPSVMESPTIQGEDIESKASLDHE-- 1123
TK+ + E + +V ++KE +I+ E+ + + E ++ E + + + E
Sbjct: 415 VTKDVEYKELVNDDV---RDKENFVIE--EDPFKGQLINEGLPVEEEFVTKELPVKEESV 469
Query: 1124 -----EEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAKTAETFSVQEAEILKTNINESE 1288
EE +TK+ +EH + ++V +S VT+ E SV E E E
Sbjct: 470 FEELTEEDQSVTKEIPVEEHSVFKEVDEIES---VTDEIVEEEGSVNE---------EVE 517
Query: 1289 AHSAIGGEEDGQE-TKENTEPSKDLKDDKEQEDSETVKTIISSDEVRSSDVQAEVFGEHT 1465
++ GE D E E E ++ + ++ +E+ + ++ +E +S+ E G T
Sbjct: 518 EEVSVSGEVDETEYVTEEVEETELVNEEVLKEEGSASEKVV-KEEGSASEKIVEEEGSVT 576
Query: 1466 EPCSSEIKDDRHG---RDESIEVKAKETGPEIETAVDGESVHE-----IETTERVLLEAX 1621
E +SE + G + S E ++ G E + E V E E+ V++E
Sbjct: 577 EETASEEIVEEEGSVTEESSSEEIVEDEGSVTEESSSEEIVEEEGSVIEESASEVIVEDE 636
Query: 1622 XXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXXXXXXXXTSVHESESLKENAEPVEAV 1801
+ +E+ + + +++ A + +
Sbjct: 637 VSASKEIVEDEASVTEEVVEEEGAVSDEVQVTESVEDEIINQGIVDEVIVEQEASVTDEI 696
Query: 1802 KNSDGT--EQISREVTVDRAKEEDIAPKTEEIQERPSESKASLEPKEEVDHISNETEEHE 1975
D + E+I+ E TV EE P EEI ++ S + E K + I ++ E
Sbjct: 697 VKEDESVIEEIAVEETVTEVVEE-TKPMDEEIVDQGSVVENVEEKKTMDEEIVDQGSVVE 755
Query: 1976 HVLERDVQQ---------CETIESEAVETKEDTQPSLDLKED--KE---TEEAETFKTVF 2113
+V E+ E +E E + T+E + + ED KE TEE E + V
Sbjct: 756 NVEEKKTMDEEIGDQGSVAEKVEEEELVTEEVIEREGSINEDIVKEASITEEVEQIEPVT 815
Query: 2114 S--------SDEVRSSAVQEEQFGEHTEPCSSEIKDESHGKEESVEVKS-QETVQDENTE 2266
+DE++ V E+ E + + +E VEV S E V++E
Sbjct: 816 GKVEKIESITDEIKEQLVPED-IKEEQLDFEEIVAQRASVNDEKVEVASITEEVEEEEKS 874
Query: 2267 DKHDVLKVPSTESEKYQGNEPETVLVSNTGSYEKS---EKSPSDLVLNVDKEELNDEK-- 2431
+VL+ + +EK V+V GS ++ E+S S + V+KEE DE+
Sbjct: 875 VSEEVLEEEGSTTEKVVKGSSTEVVVEEQGSVTENLLEEESASQGI--VEKEEFVDEEDS 932
Query: 2432 ---INVDQVDGT---QIMEEPIGLDSNGAEAEQIDQNITNETEEI-LVAKPVSLLDVKSV 2590
NV + +G+ Q++EE GL + E E++ IT +EEI V + + D+ +
Sbjct: 933 VKDQNVFEKEGSVTEQLVEEEKGLINEDNEKEEL---ITEMSEEIKSVNEEIEETDLSTE 989
Query: 2591 EQMQKPKLESPSEVSEE---TSKTVDXXXXXXXXXXVTLYQEGQVDGSYGL--ETKEETV 2755
E +++ L + V EE T K ++ L + VD + E EE
Sbjct: 990 EIIKQQGLATYEFVEEEKSLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVIEEEK 1049
Query: 2756 SVX---XXXXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKIEEKTDSIELG 2926
SV +++ + + V EK + +E G
Sbjct: 1050 SVSEEVLEEGSATEEVVEEGSCTEVVVEEGSCTEVVVEEGSCTEIVVEKGSDTEIVVEEG 1109
Query: 2927 ---EIAQEERSVTDLTPLQEESSQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSASPSKE 3097
EI EE S T++ + EE S E +E + + E ++EV+E S
Sbjct: 1110 SATEIVVEEGSATEV--VVEEGSATEEVVEEGSVSEEMLEEEGSATEEVVE--EGLSSDN 1165
Query: 3098 LEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTV----A 3265
++ V LE V D+V+V +
Sbjct: 1166 VQKSKGVIENVGEIYSVKTAKDESMNEKIPLEKSSFVDDESFKGQGPT--DNVSVEDVNS 1223
Query: 3266 EEIVDEKAK------EEVPMLQIKNEDDATK---------IHE---TRVEQARDIGPSLT 3391
E+I++E EE+P I D TK I+E VE+A+ +T
Sbjct: 1224 EDIINEHTPLEETKIEELPTEYITTADIHTKGETETKYNLIYEKINEEVEKAKFQEEKIT 1283
Query: 3392 EICSINQNQPEEQV--KEACSKEEQEKEISTN--------SENIVNETYALHSVXXXXXX 3541
E + + E + + + ++E ++KE TN +E I+ E +V
Sbjct: 1284 ENIPVERESVTEDIVQEPSLAQEVEQKESDTNEIEETKLANEKIIPEVSVTENV------ 1337
Query: 3542 XXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQDAKIVN 3721
E LD E + + + +IV
Sbjct: 1338 --VEKEGLDTEEVLEEDESITEEIVEEEVSSSEEIVEEEESSSEEIVEEEESSSE-EIVE 1394
Query: 3722 NEETTA----HESESLKGDNHQEKNAEPVEATQNLDDAEQISRE---VTVD-TEREADIT 3877
EE+++ E ES + +E+ + E + + E++ E VT + E E T
Sbjct: 1395 EEESSSEEIVEEEESSSEEIVEEEESSSEEIIEEVSSTEEVLEEEGSVTEEIVEEEVSTT 1454
Query: 3878 EKIEKV---------QEGPTVIETPTIQG----EDIESETSLE-LKEEVDQSSKDTEEHE 4015
E+++ + +EG E QG E +E+E+S E + E+V + ++ + E
Sbjct: 1455 EEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEKVLEDVGSNVEEIVQEE 1514
Query: 4016 HVLERDIPQCE---TLKAEAVDTSTVEE------AAILKTLETNISEPEAMHSETSLDLK 4168
+ ++I E T K + VD ST EE + + + +S E + E S+ +
Sbjct: 1515 GPVAQEIVHEEVSTTEKHDEVDRSTTEEIVEKVGSVSEEIIVEEVSASEEIVEEGSVTEE 1574
Query: 4169 VDKEQK------EAETVKTVIFSNE----------------------------VGTSDAQ 4246
V +E+K E E+V I E VG +
Sbjct: 1575 VVEEEKLINEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSV 1634
Query: 4247 AEEFGEHTEPCSSEIKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQSGESEKYQEN 4426
EE +H + E+K+E T + + E N +S +E +E
Sbjct: 1635 TEEIVDHGS-FAEEVKEEELVTEEAVQYEGSVTEEIKEEESITENEAIEESAFAEIIEEK 1693
Query: 4427 EPDISLVSKTENGDKFEEIPSVVEGAGLDETTHNQTLLDVESVVKQS--LDTPSE-EETS 4597
P+ + K E D EEI V E + DE + L++ + V ++ + P E E ++
Sbjct: 1694 GPNTDEIVKEEGLDT-EEI--VNEVSVTDEVIEEEKLVNEQIVGEERSVTEKPVEVERSA 1750
Query: 4598 XXXXXXXXXXXXXXVTLHQEGREEGSYGLDTKDEAVS---VLESRELGEQPQQEELCLAN 4768
V++H EGS DE+V+ V E + ++ +EE+ +
Sbjct: 1751 TEDLVEEEASVTEKVSVH-----EGSTTEQILDESVAEEIVEEEVSVDDKIIEEEVSVDE 1805
Query: 4769 EQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEI-------------SNEVIQ------- 4888
E E + EE V++ E EE+ ++ S EE+ VI+
Sbjct: 1806 VVEEEGSVIEEIVEEEESVPEEILEEELSGSEEVLEDEWVTDAFMGQEGSVIEEIEEIVD 1865
Query: 4889 ----VSSASLSEGPEYETVVEAEKIGEEQVADKIQKSFETGEIVEAHSSLPSSSEEKEHE 5056
++ + +G E +VE E E+V K + F EI+E S + + K
Sbjct: 1866 GEGSITEEIVEDGSANEKIVEEEPSRVEEVLGK--EGFVIEEIIEEGSVIEQVEDTK--- 1920
Query: 5057 TVSEKTDD----EKVKDAEPIGDMRERGLDIAETTHLSLPSVDQKEDVDEIHIPSVALPL 5224
TVSEK+++ E+VK+ + + E+ ++ E+ + V Q+E E + V+
Sbjct: 1921 TVSEKSEESSAIEEVKEVKEEESISEKIVEKEESVTEEI--VRQEESTTEKIVKDVSPTE 1978
Query: 5225 D--EQ-----EKVTSTEKGETKSSEAEDDK---PDEHVDSSTSPMLSEKNDNETQTSKTS 5374
D EQ EKV E T+ +E ++K DEH S + ++ T +
Sbjct: 1979 DFVEQTDSVTEKVIEQEGSNTEVAEDVEEKESASDEHEQEDVSVNAQVTYEKKSVTKEIV 2038
Query: 5375 EDVCMQQ---EESGTL----------------EVPKPEESKEDKSQXXXXXXXXXXXXXD 5497
++V + EE+G++ E EE ED S +
Sbjct: 2039 DEVSRTEEIVEENGSVTEGVDETGSVTEEIIEEATVTEEVVEDGS--------VTEEVVE 2090
Query: 5498 QTLPIETSHTDNTLSSELVSEQDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDAD 5677
I+ D +++ E+V E + +V + E + E +
Sbjct: 2091 DGSVIQEVVEDGSVTEEIVQENGSVTEEIVEEEGSVNEEVEEEVSVSGEVD-ETEYVTEE 2149
Query: 5678 NTLSSQLVSETKEEHKLQAGEILPTEIIPRESSDEALVSMLASREDDKVALQEDNCADDV 5857
+V E EE +GE+ TE + E +E V E+ V+ + D +
Sbjct: 2150 VEEEGSVVEEIVEEEGSVSGEVDETEYVTEEVEEEGSVVEEIVEEEGSVSGEVD---ETE 2206
Query: 5858 RETNDIQEERSISVETEESVGETKPKEHEDEIRDAHVETPTAPI--ILEENDS--ETLIA 6025
T +++EE S+ E E G + E E VE + + I+EE S E ++
Sbjct: 2207 YVTEEVEEEGSVVEEIVEEEGSVSGEVDETEYVTEEVEEEGSVVEEIVEEEGSVVEEIVE 2266
Query: 6026 EAKKGNEEINETERTVALDHEEEFVNHEAPKLEETKDEKS--QEIPETAKATETTID-QT 6196
E +E ++ETE L ++E + +AP EE +++ S EI E A E + ++
Sbjct: 2267 EEGSVSEVVDETE----LVNDE--IVEQAPFTEEVEEQVSVNDEIIEDASVAEAVEESES 2320
Query: 6197 LPIGTSQADQT-PSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETVPKES---- 6361
+ SQ ++T V +K ++T ++ + + E + KES
Sbjct: 2321 ITESVSQEEETEKGFVIEKVEETGAVTEEIVQDGLITEEILEESESVNGEIINKESDAEE 2380
Query: 6362 -----FIEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAE-------TEEKVGETKPK 6505
F+ V A E + +EG +E+ V+ E TEE V E
Sbjct: 2381 ILETEFLTEEVVGQAGSTSEEIVEEEGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVT 2440
Query: 6506 ESQAE-GAEKSDDQVEDEST------KKTDVEVAGLENDYPTEE-AEHGDETYSTLPVVG 6661
E E G + + VE+ES +T+VE + TEE + G T + G
Sbjct: 2441 EEVVEQGGSIAQEIVEEESATEEIIRDETNVEEVLEKEGSATEEIVQDGSGTNDFVGKQG 2500
Query: 6662 IXXXXXXXXXXXRAINDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDILEAKRLHG 6841
I + E+S +E +E ++ VE E+ D+LE +
Sbjct: 2501 ------------SVIEEVVEEEISTTEEKLKEEASAIEEFVE--EESIREDVLEESLVTE 2546
Query: 6842 DKSGEAEKIKEE--SGLAGKSLPIEEINLXXXXXXXXXXXXXTREIAQVLPREEILISSS 7015
+ G+ E + EE G + I E T+EI + +E L++
Sbjct: 2547 NVVGQQESVTEEIVDGEGSFTEDIVEEEESVTEEIVVDEESVTKEIVE----DEELVT-- 2600
Query: 7016 PLSAEEQEHVISDEKQEEREPQQDFNGSTSEKISLQ--VEHLKDFETSKKEQKDETHETV 7189
E ++ DE E +D T E I + +E ++D ET ++++ + +
Sbjct: 2601 -------EEIVEDEGSFTEEIVEDEGSFTEEVIEERSLIEEVEDTETVAEKEEGSVIKEI 2653
Query: 7190 XXXXXXXXXXXXXXXXXXXXXXSSEVKKDNKDARELEVGNDFVSRDGEKEEVPHNALENE 7369
E K+ + + L V + + +G + + L E
Sbjct: 2654 IDEKSLTEKIVEEEKSVTEEVEEKESVKEEVEEQRLVVEEEGSATEG----IVEDRLATE 2709
Query: 7370 EEMNEVVASEKQISDPVGVIKKASEAEH--EDPVDDIKSNDDRDFPTEQAPKDQSDE--- 7534
+++++ +E+ + D + + + E+ +DD S + E +P ++ E
Sbjct: 2710 GIVDDILVTEEIVEDGLATDEFVEQQGSIIEEVLDDEGSVTEEIVEEEGSPNEEIVEGVS 2769
Query: 7535 -VSADETVPKEAIGEELKVPSSKVLDDIQENSNTEAVTNFADRDLPVQNLSELIQS---- 7699
+ D+ + E + EE+ V S + I+E E + D D + E S
Sbjct: 2770 VIEEDDNI--EPVSEEI-VEGSVTEEMIKEGLENEVI---LDEDSITEEALEKEGSVSEE 2823
Query: 7700 --HQSPNQVEETSFEFNKAQEDKKEETVDALITNVQVQDQPKEDFEAAAIEKEISEQEHK 7873
+ + EE E ED EE A +Q + Q +E E ++ EI E++
Sbjct: 2824 IVEEMGSLTEEIVDEERSTSEDMIEEG-SASEEIIQEESQVEEVVEEVSVIDEIVEEDEL 2882
Query: 7874 LNDLTDVQEDIGTYVKVQVPDDEIKGDGHDSVAAQKEETSSIEE-KREVEHVKAEM--ED 8044
D +V E+I + V E +G + + +++E S EE EV + EM +D
Sbjct: 2883 --DTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEGSVNEEIIEEVGSITEEMVEQD 2940
Query: 8045 AIKHEVSVEEKNNTSENIDHEAAKEIEQEEGKQTNIVXXXXXXXXXXXNQESFNN---VK 8215
+E VEE++ E ++ ++ +EEG V +E + N +K
Sbjct: 2941 VSDNEEIVEERSVIEEAEENVWIEKEVEEEGLDNEEVIDEEDSVSEQAEEEVYINEEILK 3000
Query: 8216 ETDDAID-KTQPEIRDIESLSSVSKTQDKPEPEYEVPN---QQKREITNEV 8356
E+ D D K + E+ + E + E + E+ N ++ +T EV
Sbjct: 3001 ESSDVEDVKVENELMNEEVNEETQSVAENNEEDKELDNYVVEETESVTEEV 3051
Score = 253 bits (645), Expect = 5e-65
Identities = 520/2508 (20%), Positives = 945/2508 (36%), Gaps = 98/2508 (3%)
Frame = +2
Query: 359 NEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQEEDIGNISK 538
+E+ E+I+ + + + ED EEV E+ +IEE + + + E+EE G++ K
Sbjct: 2595 DEELVTEEIVEDEGSFTEEIVEDEGSFTEEVIEERSLIEEVE-DTETVAEKEE--GSVIK 2651
Query: 539 VLTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDSRTVETSVNGTEAEHNATVSVE 718
+ D + + EKS+ EE +EV E+ VE + TE ++ E
Sbjct: 2652 EIIDEKSLTEKIVEEEKSVTEEVEEKESVKEEVEEQR--LVVEEEGSATEGIVEDRLATE 2709
Query: 719 EISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNTEETTAHES 898
I D V E + ED ATD E ++++ +++E+ V +E + E
Sbjct: 2710 GIV--DDILVTEEIVEDGLATD-------EFVEQQG-----SIIEE---VLDDEGSVTEE 2752
Query: 899 KILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDKEKEEDIIQNIEEVQESPSVMESPT 1078
+ +E + EE E V + D E S E+ EE I+E E+ +++ +
Sbjct: 2753 IVEEEGSPNEEIVEGVSVIEEDDNIEPVSEEIVEGSVTEE----MIKEGLENEVILDEDS 2808
Query: 1079 IQGEDIESKASLDHE--EEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAKTAETFSVQE 1252
I E +E + S+ E EEM +T++ ++E SE ++ E +E +E
Sbjct: 2809 ITEEALEKEGSVSEEIVEEMGSLTEEIVDEER--------STSEDMIEEGSASEEIIQEE 2860
Query: 1253 AEILKTNINESEAHSAIGGEEDGQETKENTEP----SKDLKDDKEQEDSETVKTIISSDE 1420
+++ + S + EED +TKE E ++++ + KE+E S + + E
Sbjct: 2861 SQVEEVVEEVSVIDEIV--EEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKE 2918
Query: 1421 VRSSDVQAEVFGEHTEPC-------SSEIKDDRHGRDES-----IEVKAKETGPEIETAV 1564
++ E G TE + EI ++R +E+ IE + +E G + E +
Sbjct: 2919 GSVNEEIIEEVGSITEEMVEQDVSDNEEIVEERSVIEEAEENVWIEKEVEEEGLDNEEVI 2978
Query: 1565 DGE------SVHEIETTERVLLEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXX 1726
D E + E+ E +L E+ +N
Sbjct: 2979 DEEDSVSEQAEEEVYINEEILKESSDVEDVKVENELMNEEVN------------------ 3020
Query: 1727 XXXXXXTSVHESESLKENAEPVEAVKNS--DGTEQISREVTVDRAKEEDIAPKTEEIQER 1900
E++S+ EN E + + N + TE ++ EV VD P ++E+QE
Sbjct: 3021 ---------EETQSVAENNEEDKELDNYVVEETESVTEEVVVDEV------PNSKEVQEI 3065
Query: 1901 PSESKASLEPKEEVDH-ISNETEEHEHVLERDVQQCETIESEAVETKEDTQPSLDLKEDK 2077
S + +E D + + E V+E E I EA T E+ + + ED
Sbjct: 3066 ESIIEEIVEDGLTTDDLVGQQGSVIEEVVEEVGSDSEEIVEEASIT-EEVEKKESVTEDI 3124
Query: 2078 ETEEAETFKTVFS---SDEV--RSSAVQEEQFGEHTEPCSSEIKDESHGKEESVEVKS-- 2236
EE+ T + ++EV V EE E +++++ EE E++S
Sbjct: 3125 LVEESVTGDILVEGSVTEEVVGEEKLVSEEIVTEEGSVAQEIVEEDAPATEEIDEIESVT 3184
Query: 2237 QETVQDENTEDKHDVLKVPSTESEKYQGNEPETVLVSNTGS-----YEKSEKSPSDLVLN 2401
+E V++E D+ V + S E QG +V GS + + + ++V N
Sbjct: 3185 EEVVEEEGPVDEEIVQEEGSVTEEIIQGESKVEEVVEEQGSENEEIFVEEVSASQEIVQN 3244
Query: 2402 VDKEELNDEKINVDQVDGTQIMEEPIGLDSNGAEAEQIDQNITNETEEI---LVAKPVSL 2572
E EK++ Q +I+++ + E + + + + NE E I ++ + +
Sbjct: 3245 ESGTEEILEKVSASQ----EIVQDGSVTEQIIEEQKPVTEEVVNEEESITHEIIQEESHV 3300
Query: 2573 LDVKSVEQMQKPKLESPSEVSEETSK---TVDXXXXXXXXXXVTLYQEGQVDGSYGLETK 2743
V + + +E+P V+EE + +V + +E + D LE
Sbjct: 3301 EKVVQQGSVAEEVVENPVSVTEEIVEKEGSVTEDIGQEGYVAEEIVEEEEFDNEEILE-- 3358
Query: 2744 EETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKIEEKTDSIEL 2923
EE+V+ I + + K +E +EE+ E
Sbjct: 3359 EESVAEEFVEEGFDNEEIFVEQISDSEIVKEENSVNEEVLEEEGSYTEEILEEEGSYTE- 3417
Query: 2924 GEIAQEERSVTDLTPLQEESSQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSASPSKEL- 3100
EI +EE S T+ L+EE S E +E E EE +E I S ++E+
Sbjct: 3418 -EILEEEGSFTEEI-LEEEGSYNEEILEEEGSYNEEILEEEGSYNEEILEEEGSYNEEIL 3475
Query: 3101 --EGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVAEEI 3274
EG + ++ EE+
Sbjct: 3476 EEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQGSIIEEV 3535
Query: 3275 VDEKAKEEVPMLQIKNEDDATKIHETRVEQARDIGPSLTEICSINQNQPEEQVKEACSKE 3454
++E+ + + + NE AT+ ET S TE+ ++ E ++E E
Sbjct: 3536 LEEEGLDTEKVFE--NEGSATEFEETE---------SFTEVVEETESVNENILEETSINE 3584
Query: 3455 EQEKEISTNS--ENIVNETYALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXXXXXXXX 3628
Q+ E T E +V E E LD E +
Sbjct: 3585 VQKIESITEDIKEQLVPEEI--------------KEEQLDSEEIKEEQLDSEEIKEEQLV 3630
Query: 3629 XXXXXXPRLDAIXXXXXXXXXXXXQDAKIVNNEETTAHE--SESLKGDNHQEKNAEPVEA 3802
+LD+ D++ + E+ + E E L + +E+ P E
Sbjct: 3631 PEEIKEEQLDS------EEIKEEQLDSEEIKEEQLDSEEIKEEQLDSEEIKEEQLVPEEI 3684
Query: 3803 TQNLDDAEQISREVTVDTE--READITEKIEKVQEGPTVIETPTIQGEDIESET--SLEL 3970
+ D+E+I E V E E +E+I++ Q I+ + E+I+ E S E+
Sbjct: 3685 KEEQLDSEEIKEEQLVPEEIKEEQLDSEEIKEEQLDSEEIKEEQLDSEEIKEEQLDSEEI 3744
Query: 3971 KEEVDQSSKDTEEHEHVLERDIPQCETLKAEAVDTSTVEEAAILKT--LETNISEPEAMH 4144
KE+ +++ E E + +I + E E V VEE +K +E I+ E +
Sbjct: 3745 KEQKGSVNEEVVEEEGSVTEEIKEQEESVNEEV-LEEVEETESIKEEIVEGGIATQEIIE 3803
Query: 4145 SETSLDLKVDKEQKEAE------TVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDESQ 4306
E+ V++E ++E +V + EV +D EE G TE E K ++
Sbjct: 3804 EESDTKEVVEEEVIDSEKLVDAGSVTGEVMPEEVSVTDEVVEE-GSTTEEVLEEQKSVNE 3862
Query: 4307 GXXXXXXXXXXXT-VQGESSEEKDVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEEI 4483
+QG ++EE +++ EK E E T + E+
Sbjct: 3863 EVVEDGLTIDDFVGLQGSTTEE----VVEEDGSAIEKILEEE--------TATEEIVEKQ 3910
Query: 4484 PSVVEGAGLDETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXXXXXXVTLHQEGR 4663
SV E E + N+ +++ SV ++ + S E
Sbjct: 3911 VSVTEDIVEKEGSVNEEIIEEASVAEEIIQGGSFTEEIVGQEESATEEVID--------- 3961
Query: 4664 EEGSYGLDTKDEAVSVLESRELGEQPQQEELCLANEQENETKLQEEQVDKHEPTKEEVSN 4843
EEG + ++E E + + E+ +E ++ + E E E++ + E +E+
Sbjct: 3962 EEGLISNEIEEE-----EEKSVTEEMIEEVEEVSVDDEVEEVSVAEEIVEEELVDDEILP 4016
Query: 4844 DQQSPVEEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQVADKIQKSFETGEIVEAHSS 5023
++ S E++ EV V+ + E E ++E E E+ D KS T + V S
Sbjct: 4017 EELSATEDVIEEVRSVTDEIVQEESVCEEILEQEVSASEEYVD--DKSV-TDDFVGHERS 4073
Query: 5024 LPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAETTHLSLPSVDQKEDVDEIHI 5203
+ E E T D+ V + + ++G E + ++++ E+++
Sbjct: 4074 VIQDVENTESVTEEIAEVDKSVIEEA----VEKQGSVTEEKVQEGVSAIEEIEELE---- 4125
Query: 5204 PSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSPMLSEKNDNETQTSKTSEDV 5383
SV + E++K E E + S E+ +E +D T +L +K+ + DV
Sbjct: 4126 -SVTEEIAEEDKSVIEEAVEKQGSVTEEIVEEEELD--TEEVLEDKS--------VTGDV 4174
Query: 5384 CMQQEESGTLEVPKPEESKEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSELVSEQ 5563
++QE SG +ES+ +S DQ ET + + E +EQ
Sbjct: 4175 -VEQEGSGK------DESEAKESFTEEVDELKSVKEEDQ----ETEYISREIEEESATEQ 4223
Query: 5564 DDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDADNTLSSQLVSETKEEHKLQAGEI 5743
+ D+E E++ E + +++ ++V E ++ ++ ++
Sbjct: 4224 HSEQELSINKEVVETESLTKDIE--EEKSTTQEILEETQSVNEEIVEEERDTDEVLKEKV 4281
Query: 5744 LPTEIIPRESSDEALVSMLASREDDKVALQEDNCADDVRE-----TNDIQEERSISVETE 5908
P+E + E + + D++ ED ++V+E T +I EE S + E
Sbjct: 4282 SPSEEVIEEQASTTEEFVEERSSTDEIVEVEDLFTEEVKEREGSVTEEIVEEGSDTGEIV 4341
Query: 5909 ESVGETKPK------------EHEDEIRDAHVETPTAPIILEENDSETLIAEAKKGNEEI 6052
E G + E E I + ++ IL+ + +E + + EEI
Sbjct: 4342 EEEGSDTEEILEEGSFNEEIVEEEGSITEEILQGSVTEEILQGSVTEEFVGQQGSVIEEI 4401
Query: 6053 NETERTVALDHEEEFVNHEAPKLEETKDEKSQEIPETAKATETTIDQTLPIGTSQADQTP 6232
ETE + EEE E + E + +E+ + + E +I++ + S ++
Sbjct: 4402 VETESAIEERVEEESATEEVDERESVTEVVEEEVSSSDEVVEGSIEEVIENEGSVTEEIL 4461
Query: 6233 SLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETVPKESFIEAPVSMLASGED--- 6403
D+ Q T V E + TE+V +E +P + D
Sbjct: 4462 EHEVSADENFVGQAVSVIEEVEG-TESVTEEVVEETESVSEEIVEVSPTENVVQQTDSVI 4520
Query: 6404 -EPVTPQEGDYAANTQ---------EERHVSAETEEKVGETKPKESQAEGAEKSDDQVED 6553
E V +EG + EER TEE VG+ K E ++D+ E
Sbjct: 4521 EEVVEQKEGSFNEEIDIRELGDDGVEERE-KISTEEVVGQDKSATGDVEEVSSTEDEEEV 4579
Query: 6554 ESTKKTDVEVAGLENDYPTEEAEHGDETYSTLPVVGIXXXXXXXXXXXRAINDSASSEVS 6733
ST+ + EV+ E E +E ST V ++I + S E
Sbjct: 4580 SSTEGLE-EVSSTEGLEEVSNTEDVEEVSSTEDVE--EGSVAENVKETKSITEEVSVEED 4636
Query: 6734 MIKEPADQEEKKGDDVVESNEKDFVSDILEAKRLHGDKSGEAEKIKEESGLAGKSLPIEE 6913
+I + E++ + S E++ ++++ + + +K +K E ++ + + IE+
Sbjct: 4637 IITDKVSVEQEVMAEA--SVEENILTEVPVEEEIMTEKLSVEDKALNEKIMSEEEIVIED 4694
Query: 6914 INLXXXXXXXXXXXXXTREIAQVLPREEILISSSPLSAEEQEHVISDEKQEE--REPQQD 7087
N + +V+P E + P EE + S K E E D
Sbjct: 4695 GN-----------------VHEVVPAEVSVTEEIP-GVEETTNNESHVKGENVVNEVVVD 4736
Query: 7088 FNGSTSEKISLQVEHLKDFETSKKEQKDETHETVXXXXXXXXXXXXXXXXXXXXXXSSEV 7267
N E +Q + E + KD H+ + V
Sbjct: 4737 DNSVNDE---IQFDDDSSIEIYTVDSKDVFHKEENYDSFREEVRSDENIHIFRKKNENFV 4793
Query: 7268 KK-DNKDARELEVGNDFVSRDGEKEEVPHNALENEEEMNEVVASEKQISDPVGVIKKASE 7444
KK +N+ + V ++ S++ EEVP + + E EV K++ K E
Sbjct: 4794 KKIENEKSSVGHVPTEYTSKENIAEEVPSHIMFKENVTEEV---PKEV--------KYEE 4842
Query: 7445 AEHEDPVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPKEAIGEELKV 7588
E+ +++ S ++ E+AP D + E + E VP+ EE+ V
Sbjct: 4843 NTVEEVFEEVTSKEN---IIEEAPGDINSEENIIEEVPEVVTSEEIVV 4887
Score = 249 bits (635), Expect = 7e-64
Identities = 609/2900 (21%), Positives = 1099/2900 (37%), Gaps = 227/2900 (7%)
Frame = +2
Query: 344 EPQSLNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQT------EAKHSL 505
E S+NE+ E+E + +V ++ E T EE SV + ++EE+ + E ++
Sbjct: 2122 EEGSVNEEVEEEVSVSGEV---DETEYVTEEVEEEGSVVEEIVEEEGSVSGEVDETEYVT 2178
Query: 506 EQEEDIGNISKVLTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDS---RTVETSV 676
E+ E+ G++ + + + E D + + EE +E+ EE S ET
Sbjct: 2179 EEVEEEGSVVEEIVEEEGSVSGEVDETEYVTEEVEEEGSVVEEIVEEEGSVSGEVDETEY 2238
Query: 677 NGTEAEHNATVSVEEISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVED 856
E E +V VEEI + V E V E+ + + E + + E + E +VE
Sbjct: 2239 VTEEVEEEGSV-VEEIVEEEGSVVEEIVEEEGSVS--EVVDETELVNDE-------IVEQ 2288
Query: 857 AKIVN-TEETTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDKEKE-----E 1018
A EE + +I+++ + E ES T++ E++ + ++K +E E
Sbjct: 2289 APFTEEVEEQVSVNDEIIEDASVAEAVEESESITESVSQEEETEKGFVIEKVEETGAVTE 2348
Query: 1019 DIIQN---IEEVQESPSVMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVP 1189
+I+Q+ EE+ E ES ++ GE I ++ + E + +T++ Q ++
Sbjct: 2349 EIVQDGLITEEILE-----ESESVNGEIINKESDAEEILETEFLTEEVVGQAGSTSEEI- 2402
Query: 1190 VPQSETLVTEAKTAETFSVQEAEILKTNINESEAHSAIGGEEDGQETKENTEPSKDLKDD 1369
V + ++ E + E SV E + + ++ E ++G T+E E + +
Sbjct: 2403 VEEEGSVTKEVEEKE--SVTEELVDEGSVTEELV-------DEGSVTEEVVEQGGSIAQE 2453
Query: 1370 KEQEDSETVKTIISSDEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPE 1549
+E+S T + I DE +V E G TE EI D G ++ + + G
Sbjct: 2454 IVEEESATEEII--RDETNVEEV-LEKEGSATE----EIVQDGSGTNDFVG----KQGSV 2502
Query: 1550 IETAVDGESVHEIETTERVLLEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXXX 1729
IE V+ EI TTE L E +AIE+
Sbjct: 2503 IEEVVE----EEISTTEEKLKEEA----------------SAIEEFV------------- 2529
Query: 1730 XXXXXTSVHESESLKENA-EPVEAVKNSDGTEQISREVTVDRAKE--EDIAPKTEEIQER 1900
E ES++E+ E +N G ++ E VD EDI + E + E
Sbjct: 2530 ---------EEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIVEEEESVTEE 2580
Query: 1901 --PSESKASLEPKEEVDHISNETEEHEHVLERDVQQCE-TIESEAVETKEDTQPSLDLKE 2071
E + E E+ + ++ E E E ++ + E + E +E + + D +
Sbjct: 2581 IVVDEESVTKEIVEDEELVTEEIVEDEGSFTEEIVEDEGSFTEEVIEERSLIEEVEDTET 2640
Query: 2072 DKETEEAETFKTVFSSDEVRSSAVQEEQFGEHTEPCSSEIKDESHGKEESVEVKSQETVQ 2251
E EE K + + V+EE+ +K+E +E+ + V+ + +
Sbjct: 2641 VAEKEEGSVIKEIIDEKSLTEKIVEEEKSVTEEVEEKESVKEEV--EEQRLVVEEEGSAT 2698
Query: 2252 DENTEDK-------HDVL--------KVPSTESEKYQGNEPETVL---VSNTGSYEKSEK 2377
+ ED+ D+L + + E + QG+ E VL S T + E
Sbjct: 2699 EGIVEDRLATEGIVDDILVTEEIVEDGLATDEFVEQQGSIIEEVLDDEGSVTEEIVEEEG 2758
Query: 2378 SPSDLV---LNVDKEELNDEKINVDQVDGTQIMEEPI------------------GLDSN 2494
SP++ + ++V +E+ N E ++ + V+G+ + EE I L+
Sbjct: 2759 SPNEEIVEGVSVIEEDDNIEPVSEEIVEGS-VTEEMIKEGLENEVILDEDSITEEALEKE 2817
Query: 2495 GAEAEQIDQNITNETEEILVAKPVSLLDVKSVEQMQKPKLESPSEVSE--ETSKTVDXXX 2668
G+ +E+I + + + TEEI+ + + D+ + ++ S+V E E +D
Sbjct: 2818 GSVSEEIVEEMGSLTEEIVDEERSTSEDMIEEGSASEEIIQEESQVEEVVEEVSVIDEIV 2877
Query: 2669 XXXXXXXVTLYQEGQVDGSYGLETKEETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTXXX 2848
+ +E + + +E KEE SV
Sbjct: 2878 EEDELDTKEVVEEIEFNTEEVVEHKEEEGSVAEEIVQEEKEG------------------ 2919
Query: 2849 XXXXXXXXXKTVDEKIEEKTDSIELGEIAQE--ERSVTDLTPLQEESSQPNEQEKETKLE 3022
+V+E+I E E+G I +E E+ V+D + EE S E E+ +E
Sbjct: 2920 ----------SVNEEIIE-----EVGSITEEMVEQDVSDNEEIVEERSVIEEAEENVWIE 2964
Query: 3023 KHEPTNEEVKSDEVIEVLSASPSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQ 3202
K E E + ++EVI+ S S++ E E + +
Sbjct: 2965 K-EVEEEGLDNEEVIDE-EDSVSEQAEEEVYINEEILKESSDVEDVKVENELMNEEVNEE 3022
Query: 3203 TVXXXXXXXXXXXXQDHVT-VAEEIVDEKAKEEVPMLQIKNEDDATKIHETRVEQARDI- 3376
T ++V E + +E +EVP K + I E VE
Sbjct: 3023 TQSVAENNEEDKELDNYVVEETESVTEEVVVDEVP--NSKEVQEIESIIEEIVEDGLTTD 3080
Query: 3377 ------GPSLTEICSINQNQPEEQVKEACSKEEQEKEISTNSENIVNETYALHSVXXXXX 3538
G + E+ + EE V+EA EE EK+ S + +V E SV
Sbjct: 3081 DLVGQQGSVIEEVVEEVGSDSEEIVEEASITEEVEKKESVTEDILVEE-----SVTGDIL 3135
Query: 3539 XXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQ----D 3706
E + E S P + I + D
Sbjct: 3136 VEGSVTEEVVGEEKLVSEEIVTEEGSVAQEIVEEDAPATEEIDEIESVTEEVVEEEGPVD 3195
Query: 3707 AKIVNNE----------ETTAHESESLKGDNHQEKNAEPVEAT----QNLDDAEQISREV 3844
+IV E E+ E +G ++E E V A+ QN E+I +V
Sbjct: 3196 EEIVQEEGSVTEEIIQGESKVEEVVEEQGSENEEIFVEEVSASQEIVQNESGTEEILEKV 3255
Query: 3845 TVDTE--READITEKIEKVQEGPT---VIETPTIQGEDIESETSLE-------LKEEVDQ 3988
+ E ++ +TE+I + Q+ T V E +I E I+ E+ +E + EEV +
Sbjct: 3256 SASQEIVQDGSVTEQIIEEQKPVTEEVVNEEESITHEIIQEESHVEKVVQQGSVAEEVVE 3315
Query: 3989 S----SKDTEEHEHVLERDIPQCETLKAEAVDTSTVEEAAILKTLETNISEPEAMHSETS 4156
+ +++ E E + DI Q + E V+ + IL+ E +E
Sbjct: 3316 NPVSVTEEIVEKEGSVTEDIGQEGYVAEEIVEEEEFDNEEILE---------EESVAEEF 3366
Query: 4157 LDLKVDKEQKEAETVK-TVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDESQGXXXXXXXX 4333
++ D E+ E + + I E ++ EE G +TE E ++
Sbjct: 3367 VEEGFDNEEIFVEQISDSEIVKEENSVNEEVLEEEGSYTEEILEEEGSYTEEILEEEGSF 3426
Query: 4334 XXXTVQGESSEEKDVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEEIPSVVEGAGLD 4513
++ E S +++ L+ + +E+ E E + E G EEI EG+ D
Sbjct: 3427 TEEILEEEGSYNEEI--LEEEGSYNEEILEEEGSYNEEILEEEGSYNEEILE-EEGSATD 3483
Query: 4514 ----ETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXXXXXXVTLHQEGREEGSYG 4681
+ + N+ +++ S + S+ E + + EE G
Sbjct: 3484 YFVGQGSDNEEIIEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQGSIIEEVLEEE---G 3540
Query: 4682 LDTKDEAVSVLESRELGEQPQQEELCLANEQENETKLQE---EQVDKHEPTKEEVS---- 4840
LDT+ + + E E E+ E NE L+E +V K E E++
Sbjct: 3541 LDTEKVFENEGSATEFEETESFTEVVEETESVNENILEETSINEVQKIESITEDIKEQLV 3600
Query: 4841 ----NDQQSPVEEISNEVIQVSSASLSEG---PE--YETVVEAEKIGEEQV-ADKI-QKS 4987
++Q EEI E Q+ S + E PE E +++E+I EEQ+ +++I ++
Sbjct: 3601 PEEIKEEQLDSEEIKEE--QLDSEEIKEEQLVPEEIKEEQLDSEEIKEEQLDSEEIKEEQ 3658
Query: 4988 FETGEIVEAHSSLPSSSEEK--EHETVSEKTDDEKVKDAEPI-GDMRERGLDIAETTHLS 5158
++ EI E EE+ E E+ D E++K+ + + +++E LD E
Sbjct: 3659 LDSEEIKEEQLDSEEIKEEQLVPEEIKEEQLDSEEIKEEQLVPEEIKEEQLDSEEIKEEQ 3718
Query: 5159 LPSVDQKED-VDEIHIPSVAL---PLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSP 5326
L S + KE+ +D I L + EQ+ + E E + S E+ K E +S
Sbjct: 3719 LDSEEIKEEQLDSEEIKEEQLDSEEIKEQKGSVNEEVVEEEGSVTEEIKEQE--ESVNEE 3776
Query: 5327 MLSEKNDNETQTSKTSEDVCMQQ----EESGTLEVPKPEESKEDKSQXXXXXXXXXXXXX 5494
+L E + E+ + E Q EES T EV + E +K
Sbjct: 3777 VLEEVEETESIKEEIVEGGIATQEIIEEESDTKEVVEEEVIDSEK-------LVDAGSVT 3829
Query: 5495 DQTLPIETSHTDNTLSSELVSEQDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDA 5674
+ +P E S TD + +E+ + D +
Sbjct: 3830 GEVMPEEVSVTDEVVEEGSTTEEVLEEQKSVNEEVVEDGLTIDDFVGLQGSTTEEVVEED 3889
Query: 5675 DNTLSSQLVSETKEEHKLQAGEILPTEIIPRESS-DEALVSMLASRED--------DKVA 5827
+ + L ET E ++ + +I+ +E S +E ++ + E+ +++
Sbjct: 3890 GSAIEKILEEETATEEIVEKQVSVTEDIVEKEGSVNEEIIEEASVAEEIIQGGSFTEEIV 3949
Query: 5828 LQEDNCADDVRE-----TNDIQEERSISVETEESVGETKPKEHEDEIRDAHVETPTAPII 5992
QE++ ++V + +N+I+EE SV TEE + E + +DE+ + V I+
Sbjct: 3950 GQEESATEEVIDEEGLISNEIEEEEEKSV-TEEMIEEVEEVSVDDEVEEVSV---AEEIV 4005
Query: 5993 LEENDSETLIAEAKKGNEEINETERTVA---LDHE---EEFVNHEAPKLEETKDEKS--- 6145
EE + ++ E E++ E R+V + E EE + E EE D+KS
Sbjct: 4006 EEELVDDEILPEELSATEDVIEEVRSVTDEIVQEESVCEEILEQEVSASEEYVDDKSVTD 4065
Query: 6146 ------QEIPETAKATETTIDQTLPIGTS---QADQTPSLVSDKDDQTPKQVXXXXXXXX 6298
+ + + + TE+ ++ + S +A + V+++ Q
Sbjct: 4066 DFVGHERSVIQDVENTESVTEEIAEVDKSVIEEAVEKQGSVTEEKVQEGVSAIEEIEELE 4125
Query: 6299 XXTHKVQAEDIFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAETE 6478
T ++ ED +S IE V S +E V +E D E++ V+ +
Sbjct: 4126 SVTEEIAEED---------KSVIEEAVEKQGSVTEEIVEEEELD-TEEVLEDKSVTGDVV 4175
Query: 6479 EKVGETKPKESQAEGAEKSDDQVED-ESTKKTDVEVAGLENDYPTEEA--EHGDETYSTL 6649
E+ G K ++E E ++V++ +S K+ D E + + E A +H ++ S
Sbjct: 4176 EQEGSGK---DESEAKESFTEEVDELKSVKEEDQETEYISREIEEESATEQHSEQELSIN 4232
Query: 6650 PVVGIXXXXXXXXXXXRAINDSASSEVSMIKEPADQEEKKGDDVVE-------------- 6787
V ++ E + E +EE+ D+V++
Sbjct: 4233 KEVVETESLTKDIEEEKSTTQEILEETQSVNEEIVEEERDTDEVLKEKVSPSEEVIEEQA 4292
Query: 6788 SNEKDFVSDILEAKRLHGDKSGEAEKIKEESGLAGKSLPIEEINLXXXXXXXXXXXXXTR 6967
S ++FV + + + E++KE G + + E +
Sbjct: 4293 STTEEFVEERSSTDEIVEVEDLFTEEVKEREGSVTEEIVEEGSDTGEIVEEEGSDTEEIL 4352
Query: 6968 E---IAQVLPREEILISSSPLSAEEQEHVISDEKQEEREPQQDFNGSTSEKI-----SLQ 7123
E + + EE I+ L E ++ EE QQ GS E+I +++
Sbjct: 4353 EEGSFNEEIVEEEGSITEEILQGSVTEEILQGSVTEEFVGQQ---GSVIEEIVETESAIE 4409
Query: 7124 VEHLKDFETSKKEQKDETHETVXXXXXXXXXXXXXXXXXXXXXXSS--------EVKKD- 7276
++ T + ++++ E V S EV D
Sbjct: 4410 ERVEEESATEEVDERESVTEVVEEEVSSSDEVVEGSIEEVIENEGSVTEEILEHEVSADE 4469
Query: 7277 NKDARELEVGNDFVSRDGEKEEVPHNALENEEEMNEVVASEKQISDPVGVIKKASEAEHE 7456
N + + V + + EEV EE+ EV +E + VI++ E +
Sbjct: 4470 NFVGQAVSVIEEVEGTESVTEEVVEETESVSEEIVEVSPTENVVQQTDSVIEEVVEQKEG 4529
Query: 7457 DPVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPKEAIGEELKVPSSKVLDDIQENSNTE 7636
++I + D E+ K ++EV + K A G+ +V S+ +D +E S+TE
Sbjct: 4530 SFNEEIDIRELGDDGVEEREKISTEEVVGQD---KSATGDVEEVSST---EDEEEVSSTE 4583
Query: 7637 AVTNFADRD-LPVQNLSELIQSHQSPNQVEETSFEFNKAQEDKKEETV----DALITNVQ 7801
+ + + L + +E ++ S VEE S N + E V D + V
Sbjct: 4584 GLEEVSSTEGLEEVSNTEDVEEVSSTEDVEEGSVAENVKETKSITEEVSVEEDIITDKVS 4643
Query: 7802 VQDQPKEDFEAAAIEK----EISEQEHKLNDLTDVQEDIGTYVKVQVPDDEIKGDG--HD 7963
V+ +E A++E+ E+ +E + + V ED K+ ++ + DG H+
Sbjct: 4644 VE---QEVMAEASVEENILTEVPVEEEIMTEKLSV-EDKALNEKIMSEEEIVIEDGNVHE 4699
Query: 7964 SVAAQ---KEETSSIEEKREVE-HVKAEMEDAIKHEVSVEEKN-NTSENIDHEAAKEIEQ 8128
V A+ EE +EE E HVK E + +EV V++ + N D +++ EI
Sbjct: 4700 VVPAEVSVTEEIPGVEETTNNESHVKGE---NVVNEVVVDDNSVNDEIQFDDDSSIEIYT 4756
Query: 8129 EEGKQTNIVXXXXXXXXXXXNQESFNNVKETDDAIDKTQPEIRDIESLSSVSKTQDKPEP 8308
+ K N +SF +D+ I I ++ + V K +++
Sbjct: 4757 VDSKDV---------FHKEENYDSFREEVRSDENI-----HIFRKKNENFVKKIENEKSS 4802
Query: 8309 EYEVPNQ--QKREITNEVPS 8362
VP + K I EVPS
Sbjct: 4803 VGHVPTEYTSKENIAEEVPS 4822
Score = 216 bits (550), Expect = 5e-54
Identities = 580/2841 (20%), Positives = 1070/2841 (37%), Gaps = 165/2841 (5%)
Frame = +2
Query: 326 NLLSFREPQSLNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSL 505
N F + + LN++ + +II+ + K+EEDT E+ SV +EE E L
Sbjct: 45 NTEEFVQEKELNQETLENEIIVDHI----KEEEDTRNVKEQESV----LEESPIE---EL 93
Query: 506 EQEEDIGNISKVLTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDSRTVETSVNGT 685
E +IG I++ +V+E+ LN + E + + +EE + VE
Sbjct: 94 PVENNIGKINE--------EVEEF----ILNEIPLEEQVPKELPQEEIEEIVVEELPIDE 141
Query: 686 EAEHNATVSVEEISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKI 865
T EE + G E E+++ ++ P+ + +++ E K+V E+ +
Sbjct: 142 HLSSEETTVTEEDTFKGQLINEEKPVEEKSVSEEIPVEE-KSVSEEIPVEEKSVSEEIPV 200
Query: 866 VNTEETTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDKEKEEDIIQNIEEV 1045
EE + E ++E N EE VE S+ + V+ + EE+ + EE+
Sbjct: 201 ---EEKSVSEEIPVEEKNVSEEIP--VEEKNVSEEIPVEEKNVSEEIPVEEENVS--EEI 253
Query: 1046 QESPSVMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAK 1225
E +E + E + + ++D E+ DK+ + E + ++PV + ETL TE
Sbjct: 254 PEGGIAIEDVPVDEETVTEEITVD-EKIYDKLPNEIE----TVNEEMPV-EDETL-TEQI 306
Query: 1226 TAETFSVQEAEILKTNINESEAHSAIGGEEDGQETKENTEPSKDLKDDKEQEDSETVKTI 1405
++E V E I + E E ++ E + + P + + +K QE+ E V
Sbjct: 307 SSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQEEEEFVTGE 366
Query: 1406 ISSDEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPEIETAVDGESVHE 1585
+S +++ + VQ E E + E+ ++ ++ V+ +E E DG +
Sbjct: 367 LSEEDIINEKVQ-----EEDESVTEELPEEDIINEK---VQEEEESAYQEIVQDGSVTKD 418
Query: 1586 IETTERVLLEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXXXXXXXXTSVHESE 1765
+E E V N + + V E
Sbjct: 419 VEYKELV---------------------NDDVRDKENFVIEEDPFKGQLINEGLPVEEEF 457
Query: 1766 SLKENAEPVEAV--KNSDGTEQISREVTVDR----AKEEDIAPKTEEIQERPSESKASLE 1927
KE E+V + ++ + +++E+ V+ + ++I T+EI E E + E
Sbjct: 458 VTKELPVKEESVFEELTEEDQSVTKEIPVEEHSVFKEVDEIESVTDEIVEE--EGSVNEE 515
Query: 1928 PKEEVDHISNETEEHEHVLERDVQQCETIESEAVETKEDTQPSLDLKEDKETEEAETFKT 2107
+EEV +S E +E E+V E +V++ E + E ++ +E + +KE+ E +
Sbjct: 516 VEEEVS-VSGEVDETEYVTE-EVEETELVNEEVLK-EEGSASEKVVKEEGSASEKIVEEE 572
Query: 2108 VFSSDEVRSSAVQEEQFGEHTEPCSSE--IKDESHGKEESVEVKSQETVQDENTEDKHDV 2281
++E S + EE+ G TE SSE ++DE EES S+E V++E + +
Sbjct: 573 GSVTEETASEEIVEEE-GSVTEESSSEEIVEDEGSVTEES---SSEEIVEEEGSVIEESA 628
Query: 2282 LKVPSTESEKYQGNEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELNDEKINVDQVDGTQ 2461
+V E E E S T + E + SD V E + DE IN VD
Sbjct: 629 SEV-IVEDEVSASKEIVEDEASVTEEVVEEEGAVSDEVQVT--ESVEDEIINQGIVDEVI 685
Query: 2462 IMEEPIGLDSNGAEAEQIDQNITNE---TEEILVAKPVS--LLDVKSVEQMQKPKLESPS 2626
+ +E D E E + + I E TE + KP+ ++D SV + + K
Sbjct: 686 VEQEASVTDEIVKEDESVIEEIAVEETVTEVVEETKPMDEEIVDQGSVVENVEEKKTMDE 745
Query: 2627 EVSEETSKTVDXXXXXXXXXXVTLYQEGQVDGSYGLETKEETVS----VXXXXXXXXXXX 2794
E+ ++ S + T+ +E GS + +EE + +
Sbjct: 746 EIVDQGSVVENVEEKK------TMDEEIGDQGSVAEKVEEEELVTEEVIEREGSINEDIV 799
Query: 2795 XXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKIEEKTDSIELGEIAQE-ERSVTDLTPL 2971
S+ + +P EKIE TD I+ + ++ + D +
Sbjct: 800 KEASITEEVEQIEPVTGKV------------EKIESITDEIKEQLVPEDIKEEQLDFEEI 847
Query: 2972 QEESSQPNEQEKETKLEKHEPTNEEVK-SDEVIEVLSASPSKELEGETVVXXXXXXXXXX 3148
+ + N+++ E E EE S+EV+E ++ K ++G +
Sbjct: 848 VAQRASVNDEKVEVASITEEVEEEEKSVSEEVLEEEGSTTEKVVKGSSTEVVVEEQGSVT 907
Query: 3149 XXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVAEEIVDEKAKEEVPMLQIKNED 3328
+E + V + +V E++V+E+ + NED
Sbjct: 908 ENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKEGSVTEQLVEEEKG-------LINED 960
Query: 3329 DATKIHETRVEQARDIGPSLTEICSINQNQPEEQVKEACSKEEQEKEISTNSENIVNETY 3508
+ + T + + EI S+N+ E + S EE K+ + V E
Sbjct: 961 NEKEELITEMSE---------EIKSVNEEIEETDL----STEEIIKQQGLATYEFVEEEK 1007
Query: 3509 ALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXX 3688
+L + L++ TK
Sbjct: 1008 SL------------TDKLLEEESVTKEVGETELSTQEVV--------------------- 1034
Query: 3689 XXXXQDAKIVNNEETTAHES----ESLKGDNHQEKNAEPVEATQNLDDAEQISREVTVDT 3856
D K+ EE E E L+ + E+ E T+ + + E EV V+
Sbjct: 1035 -----DEKVSVTEEVIEEEKSVSEEVLEEGSATEEVVEEGSCTEVVVE-EGSCTEVVVE- 1087
Query: 3857 EREADITE-KIEKVQEGPTVIETPTIQGEDIESETSLELKEEVDQSSKDTEEH----EHV 4021
E TE +EK + V+E + +E ++ E+ E ++++ E E +
Sbjct: 1088 --EGSCTEIVVEKGSDTEIVVEEGSATEIVVEEGSATEVVVEEGSATEEVVEEGSVSEEM 1145
Query: 4022 LERDIPQCETLKAEAVDTSTVEEAAILKTLETNISEPEAMHS--ETSLDLKVDKEQK--- 4186
LE + E + E + + V+++ K + N+ E ++ + + S++ K+ E+
Sbjct: 1146 LEEEGSATEEVVEEGLSSDNVQKS---KGVIENVGEIYSVKTAKDESMNEKIPLEKSSFV 1202
Query: 4187 EAETVKTVIFSNEVGTSDAQAEEF-GEHTEPCSSEIKDESQGXXXXXXXXXXXTVQGESS 4363
+ E+ K ++ V D +E+ EHT ++I++ + +
Sbjct: 1203 DDESFKGQGPTDNVSVEDVNSEDIINEHTPLEETKIEE------LPTEYITTADIHTKGE 1256
Query: 4364 EEKDVNMLDVQSGES-EKYQENEPDISLVSKTENGDKFEEIPSVVEGAGLDETTHNQTLL 4540
E N++ + E EK + E I+ E IP VE + E + L
Sbjct: 1257 TETKYNLIYEKINEEVEKAKFQEEKIT-----------ENIP--VERESVTEDIVQEPSL 1303
Query: 4541 DVESVVKQSLDTPSEEETSXXXXXXXXXXXXXXVTLHQEG-------REEGSYGLDTKDE 4699
E K+S DT EET + +EG E+ S + +E
Sbjct: 1304 AQEVEQKES-DTNEIEETKLANEKIIPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEE 1362
Query: 4700 AVSVLESRELGEQPQQEELCLANEQENETKLQEEQ------VDKHEPTKEEVSNDQQSPV 4861
VS E E+ EE+ E +E ++EE+ V++ E + EE+ +++S
Sbjct: 1363 EVSSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSS 1422
Query: 4862 EEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQVAD--------KIQKSFETGEIVEAH 5017
EEI EV EG E +VE E E+V D ++ F T E V
Sbjct: 1423 EEIIEEVSSTEEVLEEEGSVTEEIVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQQ 1482
Query: 5018 SSLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAETTHLSLPSVDQKEDVDEI 5197
S+ E E E+ +EK ++ + E I ++E G E H + + ++ ++VD
Sbjct: 1483 GSV--IEEIVETESSTEKVLEDVGSNVEEI--VQEEGPVAQEIVHEEVSTTEKHDEVDRS 1538
Query: 5198 -------HIPSVALPLDEQEKVTS---TEKGETKSSEAEDDKPDEHVDSSTSP----MLS 5335
+ SV+ + +E S E+G E++K V + S +
Sbjct: 1539 TTEEIVEKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINEVGETESVTEEIVQK 1598
Query: 5336 EKNDNET---QTSKTSEDVCMQQEESGTLEVPKPEESKEDKSQXXXXXXXXXXXXXDQTL 5506
E +D E Q +E++ ++ES E+ PE S + + ++ +
Sbjct: 1599 EVSDAEEVLGQEGSMNEEIL--EKESIVEEIVGPEGSVTE--EIVDHGSFAEEVKEEELV 1654
Query: 5507 PIETSHTDNTLSSELVSEQ---DDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDAD 5677
E + +++ E+ E+ ++++ + E E L E +
Sbjct: 1655 TEEAVQYEGSVTEEIKEEESITENEAIEESAFAEIIEEKGPNTDEIVKEEGLDTEEIVNE 1714
Query: 5678 NTLSSQLVSETKEEHKLQAGE---ILPTEIIPRESSDEALVSMLASREDDKVALQEDNCA 5848
+++ +++ E K ++ GE + + S+ E LV AS +KV++ E +
Sbjct: 1715 VSVTDEVIEEEKLVNEQIVGEERSVTEKPVEVERSATEDLVEEEAS-VTEKVSVHEGSTT 1773
Query: 5849 DDVRETNDIQE--ERSISVE---TEESVGETKPKEHEDEIRDAHVETPTAPIILEENDSE 6013
+ + + + +E E +SV+ EE V + E E + + VE EE+ E
Sbjct: 1774 EQILDESVAEEIVEEEVSVDDKIIEEEVSVDEVVEEEGSVIEEIVEE-------EESVPE 1826
Query: 6014 TLIAEAKKGNEEINETE-RTVALDHEEEFVNHEAPKLEETKDEKSQEIPETAKATETTID 6190
++ E G+EE+ E E T A +E V E ++ + + ++EI E A E ++
Sbjct: 1827 EILEEELSGSEEVLEDEWVTDAFMGQEGSVIEEIEEIVDGEGSITEEIVEDGSANEKIVE 1886
Query: 6191 QTLP----------IGTSQADQTPSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFST 6340
+ + + S++ +D +V+ E+ S
Sbjct: 1887 EEPSRVEEVLGKEGFVIEEIIEEGSVIEQVEDTKTVSEKSEESSAIEEVKEVKEEESISE 1946
Query: 6341 ETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAETEEKVGETKPKESQAE 6520
+ V KE + + E + ++ V+ + E+ G E
Sbjct: 1947 KIVEKEESVTEEIVRQEESTTEKIVKDVSPTEDFVEQTDSVTEKVIEQEGSNTEVAEDVE 2006
Query: 6521 GAEKSDDQVEDESTKKTDVEV-AGLENDYPTEEAEHGDETYSTLPVVGIXXXXXXXXXXX 6697
E + D+ E E DV V A + + + E DE T +V
Sbjct: 2007 EKESASDEHEQE-----DVSVNAQVTYEKKSVTKEIVDEVSRTEEIVEENGSVTEGVDET 2061
Query: 6698 RAINDSASSEVSMIKEPADQEEKKGDDVVESNE--KDFVSDILEAKRLHGDKSGEAEKIK 6871
++ + E ++ +E ++ ++VVE ++ V D + + + E+I
Sbjct: 2062 GSVTEEIIEEATVTEEVV-EDGSVTEEVVEDGSVIQEVVEDGSVTEEIVQENGSVTEEIV 2120
Query: 6872 EESGLAGKSLPIEEINLXXXXXXXXXXXXXTREIAQVLPREEILISSSPLSAE-EQEHVI 7048
EE G + + EE+++ E V+ EEI+ +S E ++ +
Sbjct: 2121 EEEGSVNEEVE-EEVSVSGEVDETEYVTEEVEEEGSVV--EEIVEEEGSVSGEVDETEYV 2177
Query: 7049 SDEKQEEREPQQDFNGSTSEKISLQVEHLKDFETSKKEQKDETHETVXXXXXXXXXXXXX 7228
++E +EE GS VE + + E S + DET
Sbjct: 2178 TEEVEEE--------GSV-------VEEIVEEEGSVSGEVDETE--YVTEEVEEEGSVVE 2220
Query: 7229 XXXXXXXXXSSEVKKDNKDARELEVGNDFVSRDGEKE-EVPHNALENEEEMNEVVASEKQ 7405
S EV + E+E V E+E V +E E ++EVV +
Sbjct: 2221 EIVEEEGSVSGEVDETEYVTEEVEEEGSVVEEIVEEEGSVVEEIVEEEGSVSEVVDETEL 2280
Query: 7406 ISDPVGVIKKA---SEAEHEDPVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPKEAIGE 7576
++D ++++A E E + V+D D + + ++ VS +E K + E
Sbjct: 2281 VNDE--IVEQAPFTEEVEEQVSVNDEIIEDASVAEAVEESESITESVSQEEETEKGFVIE 2338
Query: 7577 ELK---------VPSSKVLDDIQENS---NTEAVTNFADRD--LPVQNLSELI--QSHQS 7708
+++ V + ++I E S N E + +D + L + L+E + Q+ +
Sbjct: 2339 KVEETGAVTEEIVQDGLITEEILEESESVNGEIINKESDAEEILETEFLTEEVVGQAGST 2398
Query: 7709 PNQVEETSFEFNKAQEDKK---EETVDALITNVQVQDQPKEDFE--------AAAIEKEI 7855
++ E K E+K+ EE VD ++ D+ E A I +E
Sbjct: 2399 SEEIVEEEGSVTKEVEEKESVTEELVDEGSVTEELVDEGSVTEEVVEQGGSIAQEIVEEE 2458
Query: 7856 SEQEHKLNDLTDVQEDIGTYVKVQVPDDEIKGDG---HDSVAAQ---------------- 7978
S E + D T+V+E K +EI DG +D V Q
Sbjct: 2459 SATEEIIRDETNVEE---VLEKEGSATEEIVQDGSGTNDFVGKQGSVIEEVVEEEISTTE 2515
Query: 7979 ---KEETSSIEEKREVEHVKAEM--EDAIKHEVSVEEKNNTSENIDHEAA---KEIEQEE 8134
KEE S+IEE E E ++ ++ E + V ++++ T E +D E + +E+EE
Sbjct: 2516 EKLKEEASAIEEFVEEESIREDVLEESLVTENVVGQQESVTEEIVDGEGSFTEDIVEEEE 2575
Query: 8135 GKQTNIVXXXXXXXXXXXNQESFNNVKETDDAIDKTQPEIRD--------IESLSSVSKT 8290
IV E + +D T+ + D IE S + +
Sbjct: 2576 SVTEEIVVDEESVTKEIVEDEELVTEEIVEDEGSFTEEIVEDEGSFTEEVIEERSLIEEV 2635
Query: 8291 QDKPEPEYEVPNQQKREITNE 8353
+D + +EI +E
Sbjct: 2636 EDTETVAEKEEGSVIKEIIDE 2656
Score = 203 bits (517), Expect = 3e-50
Identities = 496/2402 (20%), Positives = 913/2402 (37%), Gaps = 219/2402 (9%)
Frame = +2
Query: 1757 ESESLKENAEPVEAVKNSDGTEQISREVTVDRAKEEDIAPKTEEIQERPSESKASLEPKE 1936
ESE + +E ++ ++ +I + + ++ E+ TEE + ++ +LE +
Sbjct: 5 ESEEFPKEKYNIEDMEETEKENEIEKIMDENKETEQTEEGNTEEFVQEKELNQETLENEI 64
Query: 1937 EVDHISNE-----TEEHEHVLERDVQQCETIESEAVETKEDTQ----------------- 2050
VDHI E +E E VLE + +E+ + E+ +
Sbjct: 65 IVDHIKEEEDTRNVKEQESVLEESPIEELPVENNIGKINEEVEEFILNEIPLEEQVPKEL 124
Query: 2051 PSLDLKE--------DKETEEAETFKTVFSSDEVRSSAVQEEQFGEHTEPCSSEIKDESH 2206
P +++E D+ ET TV D + + EE+ E + S EI E
Sbjct: 125 PQEEIEEIVVEELPIDEHLSSEET--TVTEEDTFKGQLINEEKPVEE-KSVSEEIPVEEK 181
Query: 2207 GKEESVEVKSQETVQDENTEDKHDVLKVP------STESEKYQGNEPETVLVSNTGSYEK 2368
E + V+ + ++ E+K ++P S E + N E + V E+
Sbjct: 182 SVSEEIPVEEKSVSEEIPVEEKSVSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEKNVSEE 241
Query: 2369 --------SEKSPSDLVLNVD---KEELNDEKINVDQVDGTQIMEEPIGLDSN-GAEAEQ 2512
SE+ P + D EE E+I VD+ ++ E ++ E E
Sbjct: 242 IPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEEMPVEDET 301
Query: 2513 IDQNITNE----TEEILVAKPV-------SLLDVKSVEQMQKPKLESPSEVSEETSKTVD 2659
+ + I++E EEI+ KP SL D E + + ++E+ + +
Sbjct: 302 LTEQISSEHERVPEEIIEEKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQEEEE 361
Query: 2660 XXXXXXXXXXVTLYQEGQVDGSYGLETKEETVSVXXXXXXXXXXXXXRSVIDPTPLQKPT 2839
+ + + D S E EE + + ++ + K
Sbjct: 362 FVTGELSEEDIINEKVQEEDESVTEELPEE--DIINEKVQEEEESAYQEIVQDGSVTKDV 419
Query: 2840 XXXXXXXXXXXXKT--VDEKIEEKTDSIELGEIAQEERSVTDLTPLQEESSQPNEQEKET 3013
K V E+ K I G + EE VT P++EES E++
Sbjct: 420 EYKELVNDDVRDKENFVIEEDPFKGQLINEG-LPVEEEFVTKELPVKEESVFEELTEEDQ 478
Query: 3014 KLEKHEPTNEEVKSDEVIEVLSASPSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLE 3193
+ K P E EV E+ S + + +E E V +E
Sbjct: 479 SVTKEIPVEEHSVFKEVDEIESVT-DEIVEEEGSVNEEVEEEVSVSGEVDETEYVTEEVE 537
Query: 3194 TVQTVXXXXXXXXXXXXQDHV----TVAEEIVDEKAK--EEVPMLQIKNEDDATKIHETR 3355
+ V + V + +E+IV+E+ EE +I E+ + +
Sbjct: 538 ETELVNEEVLKEEGSASEKVVKEEGSASEKIVEEEGSVTEETASEEIVEEEGSVTEESSS 597
Query: 3356 VEQARDIGPSLTEICSINQNQPEE--QVKEACSKEEQEKEISTNSENIVNETYALHSVXX 3529
E D G S+TE S + EE ++E+ S+ E E+S + E + +E V
Sbjct: 598 EEIVEDEG-SVTEESSSEEIVEEEGSVIEESASEVIVEDEVSASKEIVEDEASVTEEV-- 654
Query: 3530 XXXXXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQDA 3709
G D+V+ T+S D I Q+A
Sbjct: 655 ----VEEEGAVSDEVQVTESVE--------------------DEIINQGIVDEVIVEQEA 690
Query: 3710 KIVNNEETTAHESESLKGDNHQEKNAEPVEATQNLDD--------AEQISREVTVDTERE 3865
+ +E + ++ +E E VE T+ +D+ E + + T+D E
Sbjct: 691 SV--TDEIVKEDESVIEEIAVEETVTEVVEETKPMDEEIVDQGSVVENVEEKKTMD-EEI 747
Query: 3866 ADITEKIEKVQEGPTVIETPTIQGEDIE--SETSLELKEEVDQSSKDTEE--HEHVLERD 4033
D +E V+E T+ E QG E E L +E +++ E+ E + +
Sbjct: 748 VDQGSVVENVEEKKTMDEEIGDQGSVAEKVEEEELVTEEVIEREGSINEDIVKEASITEE 807
Query: 4034 IPQCETLKAEAVDTSTVEEAAILKTLETNISEPEAMHSE-TSLDLKVDKEQKEAETVKTV 4210
+ Q E + + ++ + + + +I E + E + V+ E+ E ++
Sbjct: 808 VEQIEPVTGKVEKIESITDEIKEQLVPEDIKEEQLDFEEIVAQRASVNDEKVEVASITEE 867
Query: 4211 IFSNEVGTSDAQAEEFGEHTEP----CSSEIKDESQGXXXXXXXXXXXTVQG-------- 4354
+ E S+ EE G TE S+E+ E QG QG
Sbjct: 868 VEEEEKSVSEEVLEEEGSTTEKVVKGSSTEVVVEEQGSVTENLLEEESASQGIVEKEEFV 927
Query: 4355 -ESSEEKDVNMLDVQSGESEKYQENEPDISLVSKTENGDKF-----EEIPSV-------- 4492
E KD N+ + + +E+ E E L+++ ++ EEI SV
Sbjct: 928 DEEDSVKDQNVFEKEGSVTEQLVEEEK--GLINEDNEKEELITEMSEEIKSVNEEIEETD 985
Query: 4493 ------VEGAGL-------DETTHNQTLLDVESVVKQSLDTP-SEEETSXXXXXXXXXXX 4630
++ GL +E + LL+ ESV K+ +T S +E
Sbjct: 986 LSTEEIIKQQGLATYEFVEEEKSLTDKLLEEESVTKEVGETELSTQEVVDEKVSVTEEVI 1045
Query: 4631 XXXVTLHQEGREEGSYGLDTKDEAVS---VLESRELGEQPQQEELC--LANEQENETKLQ 4795
++ +E EEGS + +E V+E E +E C + E+ ++T++
Sbjct: 1046 EEEKSVSEEVLEEGSATEEVVEEGSCTEVVVEEGSCTEVVVEEGSCTEIVVEKGSDTEIV 1105
Query: 4796 EEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQV-AD 4972
E+ E EE + + VEE S V S+SE E E++ EE + +D
Sbjct: 1106 VEEGSATEIVVEE-GSATEVVVEEGSATEEVVEEGSVSEEMLEEEGSATEEVVEEGLSSD 1164
Query: 4973 KIQKS----FETGEIVEAHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIA 5140
+QKS GEI ++ S EK S DDE K P
Sbjct: 1165 NVQKSKGVIENVGEIYSVKTAKDESMNEKIPLEKSSFVDDESFKGQGP------------ 1212
Query: 5141 ETTHLSLPSVDQKEDVDEIHIPSVALPLDE--QEKVTSTE---KGETKSS-EAEDDKPDE 5302
T ++S+ V+ ++ ++E H P ++E E +T+ + KGET++ +K +E
Sbjct: 1213 -TDNVSVEDVNSEDIINE-HTPLEETKIEELPTEYITTADIHTKGETETKYNLIYEKINE 1270
Query: 5303 HVDSSTSPMLSEKNDNETQTSKTSEDVCMQQEESGTLEVPKPEESKEDKSQXXXXXXXXX 5482
V+ + + Q K +E++ +++E V +P ++E + +
Sbjct: 1271 EVEKA-----------KFQEEKITENIPVERESVTEDIVQEPSLAQEVEQKESDTNEIEE 1319
Query: 5483 XXXXDQTLPIETSHTDNTL------SSELVSEQDDQSPXXXXXXXXXXXXXAHDVEATSE 5644
++ + E S T+N + + E++ E + + + E++SE
Sbjct: 1320 TKLANEKIIPEVSVTENVVEKEGLDTEEVLEEDESITEEIVEEEVSSSEEIVEEEESSSE 1379
Query: 5645 RNLPVETSDADNTLSSQLVS--ETKEEHKLQAGEILPTEIIPRESSDEALVSMLASRE-- 5812
+ E S ++ + + S E EE + + EI+ E ESS E ++ ++S E
Sbjct: 1380 EIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEEE----ESSSEEIIEEVSSTEEV 1435
Query: 5813 -DDKVALQEDNCADDVRETNDIQEERSISVET--EESVGETKPKEHEDEIRDAHVETPTA 5983
+++ ++ E+ ++V T ++++ S+S E EE G + + + + VET ++
Sbjct: 1436 LEEEGSVTEEIVEEEVSTTEEVKDIGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESS 1495
Query: 5984 -PIILEENDSETLIAEAKKG-------NEEINETERTVALDHE--EEFVNHEAPKLEETK 6133
+LE+ S ++G +EE++ TE+ +D EE V EE
Sbjct: 1496 TEKVLEDVGSNVEEIVQEEGPVAQEIVHEEVSTTEKHDEVDRSTTEEIVEKVGSVSEEII 1555
Query: 6134 DEK---SQEIPETAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTPKQVXXXXXXXXXX 6304
E+ S+EI E TE +++ I ++ +T S+ ++ K+V
Sbjct: 1556 VEEVSASEEIVEEGSVTEEVVEEEKLI--NEVGETESVT---EEIVQKEV-------SDA 1603
Query: 6305 THKVQAEDIFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAETEEK 6484
+ E + E + KES +E V S +E V G +A +EE V+ E +
Sbjct: 1604 EEVLGQEGSMNEEILEKESIVEEIVGPEGSVTEEIV--DHGSFAEEVKEEELVTEEAVQY 1661
Query: 6485 VGETKPKESQAEGAEKSDDQVEDESTKKTDVEVAGLENDYPTEEAEHGDETYSTLPVVGI 6664
G + + E ++++ +ES +E G D +E E T +V
Sbjct: 1662 EGSVTEEIKEEESI--TENEAIEESAFAEIIEEKGPNTDEIVKE-----EGLDTEEIVNE 1714
Query: 6665 XXXXXXXXXXXRAINDS-ASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDILEAKRLHG 6841
+ +N+ E S+ ++P + E +D+VE + + E +H
Sbjct: 1715 VSVTDEVIEEEKLVNEQIVGEERSVTEKPVEVERSATEDLVEEE-----ASVTEKVSVHE 1769
Query: 6842 DKSGE-------AEKIKEESGLAGKSLPIEEINLXXXXXXXXXXXXXTREIAQVLPREEI 7000
+ E AE+I EE + EE+++ E + +P E
Sbjct: 1770 GSTTEQILDESVAEEIVEEEVSVDDKIIEEEVSVDEVVEEEGSVIEEIVEEEESVPEE-- 1827
Query: 7001 LISSSPLSAEEQEHVISDE------------KQEEREPQQDFNGSTSEKISLQVEHLKDF 7144
I LS E+ V+ DE EE E D GS +E+I VE
Sbjct: 1828 -ILEEELSGSEE--VLEDEWVTDAFMGQEGSVIEEIEEIVDGEGSITEEI---VEDGSAN 1881
Query: 7145 ETSKKEQKDETHETVXXXXXXXXXXXXXXXXXXXXXXSSEVKKDNKDARELEVGNDFVSR 7324
E +E+ E + + V + ++++ +E V
Sbjct: 1882 EKIVEEEPSRVEEVLGKEGFVIEEIIEEGSVIEQVEDTKTVSEKSEESSAIEE----VKE 1937
Query: 7325 DGEKEEVPHNALENEEEMNEVV------ASEKQISD--PVGVIKKASEAEHEDPVDDIKS 7480
E+E + +E EE + E + +EK + D P + +++ E ++ S
Sbjct: 1938 VKEEESISEKIVEKEESVTEEIVRQEESTTEKIVKDVSPTEDFVEQTDSVTEKVIEQEGS 1997
Query: 7481 NDD--RDFPTEQAPKDQSDE----VSADETVPKEAIGEELKVPSSKVLDDIQENSNTEAV 7642
N + D +++ D+ ++ V+A T K+++ +E+ S+ + ++EN +V
Sbjct: 1998 NTEVAEDVEEKESASDEHEQEDVSVNAQVTYEKKSVTKEIVDEVSRTEEIVEENG---SV 2054
Query: 7643 TNFADRDLPVQNLSELIQSHQSPNQVEETSFEFNKAQEDK---KEETVDALITNVQVQDQ 7813
T D V E+I+ +V E + ED +E D +T VQ
Sbjct: 2055 TEGVDETGSV--TEEIIEEATVTEEVVEDGSVTEEVVEDGSVIQEVVEDGSVTEEIVQ-- 2110
Query: 7814 PKEDFEAAAIEKEISEQEHKLNDLTDVQEDI---GTYVKVQVPDDEIKGDG--------- 7957
E ++ +EI E+E +N+ +V+E++ G + + +E++ +G
Sbjct: 2111 -----ENGSVTEEIVEEEGSVNE--EVEEEVSVSGEVDETEYVTEEVEEEGSVVEEIVEE 2163
Query: 7958 HDSVAAQKEETSSIEEKREVEHVKAEMEDAIKHEVS----VEEKNNTSENIDHEAA--KE 8119
SV+ + +ET + E EVE + +E+ ++ E S V+E +E ++ E + +E
Sbjct: 2164 EGSVSGEVDETEYVTE--EVEEEGSVVEEIVEEEGSVSGEVDETEYVTEEVEEEGSVVEE 2221
Query: 8120 IEQEEGKQTNIVXXXXXXXXXXXNQESFNNVKETDDAIDKTQPEIRDIESLSSVSKTQDK 8299
I +EEG + V +E + V+E + EI +E SVS+ D+
Sbjct: 2222 IVEEEGSVSGEVDETEYVTEEV--EEEGSVVEEIVEEEGSVVEEI--VEEEGSVSEVVDE 2277
Query: 8300 PE 8305
E
Sbjct: 2278 TE 2279
Score = 177 bits (450), Expect = 2e-42
Identities = 474/2189 (21%), Positives = 831/2189 (37%), Gaps = 150/2189 (6%)
Frame = +2
Query: 2237 QETVQDENTEDKHDVLKVPSTESEKYQGNEPETVLVSNTGSYEKSEKSPSDLVLNVDKEE 2416
+E +E ++K+++ + TE E NE E ++ N + + E + + V ++E
Sbjct: 2 KELESEEFPKEKYNIEDMEETEKE----NEIEKIMDENKETEQTEEGNTEEFV---QEKE 54
Query: 2417 LNDE----KINVDQV----DGTQIMEEPIGLDSNGAEAEQIDQNITNETEEILVAKPVSL 2572
LN E +I VD + D + E+ L+ + E ++ NI EE+ + L
Sbjct: 55 LNQETLENEIIVDHIKEEEDTRNVKEQESVLEESPIEELPVENNIGKINEEV---EEFIL 111
Query: 2573 LDVKSVEQMQKPKLESPSEVSEETSKTVDXXXXXXXXXXVTLYQEGQVDGSYGLETK--- 2743
++ EQ+ K E P E EE T+ +E G E K
Sbjct: 112 NEIPLEEQVPK---ELPQEEIEEIVVEELPIDEHLSSEETTVTEEDTFKGQLINEEKPVE 168
Query: 2744 ----EETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKI--EEK 2905
E + V +SV + P+++ + K V E+I EEK
Sbjct: 169 EKSVSEEIPVEEKSVSEEIPVEEKSVSEEIPVEEKSVSEEIPVEE---KNVSEEIPVEEK 225
Query: 2906 TDSIELGEIAQEERSVTDLTPLQEESSQPNEQEKETKLE----KHEPTNEEVKSDEVI-- 3067
S EI EE++V++ P++EE+ E +E E EE+ DE I
Sbjct: 226 NVS---EEIPVEEKNVSEEIPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYD 282
Query: 3068 ----EVLSASPSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQTVXXXXXXXXX 3235
E+ + + +E ET+ S E +
Sbjct: 283 KLPNEIETVNEEMPVEDETL-------------------TEQISSEHERVPEEIIEEKPF 323
Query: 3236 XXXQDHVTVAEEIVDE-KAKEEVPMLQIKNEDDATKIHETRVEQARDIGPSLTEICSINQ 3412
++ ++ +EIV+E +++P QI I E E+ + L+E IN+
Sbjct: 324 TEGEETESLTDEIVEEGVVTDDIPEEQI--------ITEKVQEEEEFVTGELSEEDIINE 375
Query: 3413 NQPEEQVKEACSKEEQEKEISTNSENIVNETYALHSVXXXXXXXXXNGESL--DDVETTK 3586
EE E+ ++E E++I E+ V + L DDV +
Sbjct: 376 KVQEED--ESVTEELPEEDIINEKVQEEEESAYQEIVQDGSVTKDVEYKELVNDDVRDKE 433
Query: 3587 SXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQDAKIVNNEETTAHES--ESLK 3760
+ ++ + + V E ES E L
Sbjct: 434 NFV-------------------IEEDPFKGQLINEGLPVEEEFVTKELPVKEESVFEELT 474
Query: 3761 GDNHQEKNAEPVEATQNLDDAEQISREVTVDTEREADITEKI-EKVQEGPTVIETPTIQG 3937
++ PVE + ++I E E + E++ E+V V ET +
Sbjct: 475 EEDQSVTKEIPVEEHSVFKEVDEIESVTDEIVEEEGSVNEEVEEEVSVSGEVDETEYVTE 534
Query: 3938 EDIESETSLE--LKEEVDQSSKDTEEHEHVLERDIPQCETLKAEAVDTSTVEEAAIL--K 4105
E E+E E LKEE S K +E E+ + + ++ E VEE + +
Sbjct: 535 EVEETELVNEEVLKEEGSASEKVVKEEGSASEKIVEEEGSVTEETASEEIVEEEGSVTEE 594
Query: 4106 TLETNISEPEAMHSETSLDLKVDKEQKEA--ETVKTVIFSNEVGTSDAQAEEFGEHTEPC 4279
+ I E E +E S ++ +E+ E+ VI +EV S E+ TE
Sbjct: 595 SSSEEIVEDEGSVTEESSSEEIVEEEGSVIEESASEVIVEDEVSASKEIVEDEASVTEEV 654
Query: 4280 SSE---IKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLD--VQSGES--EKYQENEPDI 4438
E + DE Q + E E++ ++ D V+ ES E+ E
Sbjct: 655 VEEEGAVSDEVQVTESVEDEIINQGIVDEVIVEQEASVTDEIVKEDESVIEEIAVEETVT 714
Query: 4439 SLVSKTENGDKFEEI---PSVVEGAGLDETTHNQTLLDVESVVKQSLDTPSEEETSXXXX 4609
+V +T+ D EEI SVVE ++ T ++ ++D SVV+ + + +E
Sbjct: 715 EVVEETKPMD--EEIVDQGSVVENVE-EKKTMDEEIVDQGSVVENVEEKKTMDEEIGDQG 771
Query: 4610 XXXXXXXXXXVTLHQEGREEGSYGLDTKDEAVSVLESREL-------------------- 4729
+ + EGS D EA E ++
Sbjct: 772 SVAEKVEEEELVTEEVIEREGSINEDIVKEASITEEVEQIEPVTGKVEKIESITDEIKEQ 831
Query: 4730 -------GEQPQQEELCLANEQENETKLQ-----EEQVDKHEPTKEEVSNDQQSPVEEI- 4870
EQ EE+ N+ K++ EE ++ + EEV ++ S E++
Sbjct: 832 LVPEDIKEEQLDFEEIVAQRASVNDEKVEVASITEEVEEEEKSVSEEVLEEEGSTTEKVV 891
Query: 4871 ---SNEVI-----QVSSASLSEGPEYETVVEAEKIGEEQVADKIQKSFE-----TGEIVE 5011
S EV+ V+ L E + +VE E+ +E+ + K Q FE T ++VE
Sbjct: 892 KGSSTEVVVEEQGSVTENLLEEESASQGIVEKEEFVDEEDSVKDQNVFEKEGSVTEQLVE 951
Query: 5012 AHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAETTHLSLPSVDQKEDVD 5191
L + EKE E ++E +++ K + E E T LS + +++ +
Sbjct: 952 EEKGLINEDNEKE-ELITEMSEEIKSVNEE------------IEETDLSTEEIIKQQGLA 998
Query: 5192 EIHI----PSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSPMLSEKNDNETQ 5359
S+ L E+E VT E GET+ S E DE V + + EK+ +E
Sbjct: 999 TYEFVEEEKSLTDKLLEEESVTK-EVGETELSTQE--VVDEKVSVTEEVIEEEKSVSEEV 1055
Query: 5360 TSKTSEDVCMQQEESGTLEVPKPEESKEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTL 5539
+ S + +E S T V + E + D + +E
Sbjct: 1056 LEEGSATEEVVEEGSCTEVVVEEGSCTEVVVEEGSCTEIVVEKGSDTEIVVEEGS----- 1110
Query: 5540 SSELVSEQDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDADNTLSSQLVSETKEE 5719
++E+V E+ S + + SE L E S + + L S+ ++
Sbjct: 1111 ATEIVVEEG--SATEVVVEEGSATEEVVEEGSVSEEMLEEEGSATEEVVEEGLSSDNVQK 1168
Query: 5720 HK---LQAGEILPTEIIPRESSDEALVSMLASREDDKVALQEDNCADDVRETNDIQEERS 5890
K GEI + ES +E + +S DD+ + + D+V D+ E
Sbjct: 1169 SKGVIENVGEIYSVKTAKDESMNEKIPLEKSSFVDDE-SFKGQGPTDNV-SVEDVNSEDI 1226
Query: 5891 ISVET--EESVGETKPKEHEDEIRDAHV--ETPTAPIILEENDSETLIAEAKKGNEEINE 6058
I+ T EE+ E P E+ D H ET T ++ E +E + +AK E+I E
Sbjct: 1227 INEHTPLEETKIEELPTEY-ITTADIHTKGETETKYNLIYEKINEE-VEKAKFQEEKITE 1284
Query: 6059 TERTVALDHEEEFVNHEAPKLE-ETKDEKSQEIPETAKATETTIDQ---TLPIGTSQADQ 6226
E+ V + E E K+ + EI ET A E I + T + +
Sbjct: 1285 NIPVERESVTEDIVQEPSLAQEVEQKESDTNEIEETKLANEKIIPEVSVTENVVEKEGLD 1344
Query: 6227 TPSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETV-PKESFIEAPVSMLASGED 6403
T ++ + + T + V V+ E+ S E V +ES E V S +
Sbjct: 1345 TEEVLEEDESITEEIVEEEVSSSEEI---VEEEESSSEEIVEEEESSSEEIVEEEESSSE 1401
Query: 6404 EPVTPQEGDYAANTQEERHVSAETEEKVGETKPKESQAEGAEKSDDQVEDESTKKTDVEV 6583
E V +E +EE S E E+V T +E E +++ VE+E + +V+
Sbjct: 1402 EIVEEEESSSEEIVEEEESSSEEIIEEVSST--EEVLEEEGSVTEEIVEEEVSTTEEVKD 1459
Query: 6584 AGLENDYPTEEAEHGDETYSTLPVVGIXXXXXXXXXXXRAINDSASSEVSMIKE--PADQ 6757
G ++ EE G E + I + + D S+ +++E P Q
Sbjct: 1460 IGSVSEEVLEEEGFGTEEFVGQQGSVIEEIVETESSTEKVLEDVGSNVEEIVQEEGPVAQ 1519
Query: 6758 E--------EKKGDDVVESNEKDFVSDI-LEAKRLHGDKSGEAEKIKEESGLAGKSLPIE 6910
E +K D+V S ++ V + ++ + ++ +E+I EE + + + E
Sbjct: 1520 EIVHEEVSTTEKHDEVDRSTTEEIVEKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEEE 1579
Query: 6911 EINLXXXXXXXXXXXXXTREIAQ--VLPREEILISSSPLSAE--EQEHVISDEKQEEREP 7078
++ T EI Q V EE+L ++ E E+E ++ + E
Sbjct: 1580 KL-----INEVGETESVTEEIVQKEVSDAEEVLGQEGSMNEEILEKESIVEEIVGPEGSV 1634
Query: 7079 QQDF--NGSTSEKI---SLQVEHLKDFETSKKEQKDETHETVXXXXXXXXXXXXXXXXXX 7243
++ +GS +E++ L E +E S E+ E E++
Sbjct: 1635 TEEIVDHGSFAEEVKEEELVTEEAVQYEGSVTEEIKE-EESITENEAIEESAFAEIIEEK 1693
Query: 7244 XXXXSSEVKKDNKDARELEVGNDFVSRDGEKEEVPHNALENEEEMNE-VVASEKQISD-P 7417
VK++ D E+ + V +E E+ +NE +V E+ +++ P
Sbjct: 1694 GPNTDEIVKEEGLDTEEIV----------NEVSVTDEVIEEEKLVNEQIVGEERSVTEKP 1743
Query: 7418 VGVIKKASEAEHEDPVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPKEAIGEELKVPSS 7597
V V + A+ ED V++ S ++ E + +Q DE+V +E + EE+ V
Sbjct: 1744 VEVERSAT----EDLVEEEASVTEKVSVHEGSTTEQ----ILDESVAEEIVEEEVSVDDK 1795
Query: 7598 KVLDDI-------QENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQVEETSFEFNKAQE 7756
+ +++ +E S E + + +P + L E + + + E + F +
Sbjct: 1796 IIEEEVSVDEVVEEEGSVIEEIVE-EEESVPEEILEEELSGSEEVLEDEWVTDAFMGQEG 1854
Query: 7757 DKKEETVDALITNVQVQDQPKEDFEA--AAIEKEISEQEHKLNDLTDVQEDI---GTYVK 7921
EE + + + ++ ED A +E+E S E L V E+I G+ ++
Sbjct: 1855 SVIEEIEEIVDGEGSITEEIVEDGSANEKIVEEEPSRVEEVLGKEGFVIEEIIEEGSVIE 1914
Query: 7922 VQVPDDEIKGDGHDSVAAQKEETSSIEEKREVEHVKAEMEDAIKHEVSV-EEKNNTSENI 8098
QV D + +V+ + EE+S+IEE +EV+ ++ E ++ E SV EE E+
Sbjct: 1915 -QVEDTK-------TVSEKSEESSAIEEVKEVKEEESISEKIVEKEESVTEEIVRQEEST 1966
Query: 8099 DHEAAKEIEQEEG--KQTNIVXXXXXXXXXXXNQESFNNVKETDDAIDKTQPEIRDIESL 8272
+ K++ E +QT+ V N E +V+E + A D+ + E D+
Sbjct: 1967 TEKIVKDVSPTEDFVEQTDSV-TEKVIEQEGSNTEVAEDVEEKESASDEHEQE--DVSVN 2023
Query: 8273 SSVSKTQDKPEPEYEVPNQQKR--EITNE 8353
+ V T +K E+ ++ R EI E
Sbjct: 2024 AQV--TYEKKSVTKEIVDEVSRTEEIVEE 2050
Score = 152 bits (385), Expect = 7e-35
Identities = 333/1633 (20%), Positives = 614/1633 (37%), Gaps = 86/1633 (5%)
Frame = +2
Query: 3725 EETTAHESESLKGDNHQEKNAEPVEATQNLD-DAEQISREVTVDTEREADITEKIEKV-Q 3898
EE E ++ +N E+ E A +++ D E ++ E+TVD + + +IE V +
Sbjct: 234 EEKNVSEEIPVEEENVSEEIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNE 293
Query: 3899 EGPTVIETPTIQ--------GEDIESETSLELKEEVDQSSKDTEEHEHVLERDIPQCETL 4054
E P ET T Q E+I E EE + + + E E V+ DIP+ + +
Sbjct: 294 EMPVEDETLTEQISSEHERVPEEIIEEKPFTEGEETESLTDEIVE-EGVVTDDIPEEQII 352
Query: 4055 -----KAEAVDTSTVEEAAIL--KTLETNISEPEAMHSETSLDLKVDKEQKEAETVKTVI 4213
+ E T + E I+ K E + S E + E D+ +K Q+E E+ I
Sbjct: 353 TEKVQEEEEFVTGELSEEDIINEKVQEEDESVTEELPEE---DIINEKVQEEEESAYQEI 409
Query: 4214 FSNEVGTSDAQAEEFGEHTEPCSSEIKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLDV 4393
+ T D E+ E + +++D+ +G EE+ V ++
Sbjct: 410 VQDGSVTKDV------EYKELVNDDVRDKENFVIEEDPFKGQLINEGLPVEEEFVTK-EL 462
Query: 4394 QSGESEKYQENEPDISLVSKTENGDKFEEIPSVVEGAGLDETTHNQTLLDVESVVKQSLD 4573
E ++E + V+K EIP V E + E +++ D + S++
Sbjct: 463 PVKEESVFEELTEEDQSVTK--------EIP-VEEHSVFKEVDEIESVTDEIVEEEGSVN 513
Query: 4574 TPSEEETSXXXXXXXXXXXXXXVTLHQEGREEGSYGLDTKDEAVSVLESRELGEQPQQEE 4753
EEE S V + EE + E V V E E+ +EE
Sbjct: 514 EEVEEEVSVSGEVDETEYVTEEVEETELVNEEVLKEEGSASEKV-VKEEGSASEKIVEEE 572
Query: 4754 LCLANEQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGPEYETV 4933
+ E +E ++EE E + EE+ D+ S EE S+E I S+ E E +
Sbjct: 573 GSVTEETASEEIVEEEGSVTEESSSEEIVEDEGSVTEESSSEEIVEEEGSVIEESASEVI 632
Query: 4934 VEAEKIGEEQVADKIQKSFETGEIVEAHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIGD 5113
VE E +++ + ++ T E+VE ++ S E + E+V ++ ++ + D +
Sbjct: 633 VEDEVSASKEIVE--DEASVTEEVVEEEGAV--SDEVQVTESVEDEIINQGIVDEVIVEQ 688
Query: 5114 MRERGLDIAETTHLSLPSVDQKEDVDEIHIPSVALPLDEQEKVTSTEKGETKSSEAEDDK 5293
+I + + + +E V E + P+DE+ ++G + E
Sbjct: 689 EASVTDEIVKEDESVIEEIAVEETVTE--VVEETKPMDEE----IVDQGSVVENVEEKKT 742
Query: 5294 PDEHV---DSSTSPMLSEKNDNETQTSKTSEDVCMQQEESGTLEVPKPEESKEDKSQXXX 5464
DE + S + +K +E + S +++EE T EV + E S +
Sbjct: 743 MDEEIVDQGSVVENVEEKKTMDEEIGDQGSVAEKVEEEELVTEEVIEREGSINEDIVKEA 802
Query: 5465 XXXXXXXXXXDQTLPIETSHTDNTLSSELVSEQDDQSPXXXXXXXXXXXXXAHDVEATSE 5644
T +E + E + +D + +D E
Sbjct: 803 SITEEVEQIEPVTGKVEKIESITDEIKEQLVPEDIKEEQLDFEEIVAQRASVND-EKVEV 861
Query: 5645 RNLPVETSDADNTLSSQLVSETKEEHKLQAGEILPTEIIPRESSDEALVSMLASREDDKV 5824
++ E + + ++S +++ E E TE + + SS E +V S ++
Sbjct: 862 ASITEEVEEEEKSVSEEVLEE----------EGSTTEKVVKGSSTEVVVEEQGSVTEN-- 909
Query: 5825 ALQEDNCADDVRETNDIQEERSISVETEESVGETKPKEHEDEIRDAHVETPTAPIILEEN 6004
L+E++ + + E + V+ E+SV + E E + + VE +I E+N
Sbjct: 910 LLEEESASQGIVEKEEF-------VDEEDSVKDQNVFEKEGSVTEQLVEEEKG-LINEDN 961
Query: 6005 DSETLIAEAKKGNEEINETERTVALDHEE----------EFVNHEAPKLEETKDEKS--Q 6148
+ E LI E + + +NE L EE EFV E ++ +E+S +
Sbjct: 962 EKEELITEMSEEIKSVNEEIEETDLSTEEIIKQQGLATYEFVEEEKSLTDKLLEEESVTK 1021
Query: 6149 EIPETAKATETTIDQTLPIGTSQADQTPSL---VSDKDDQTPKQVXXXXXXXXXXTHKVQ 6319
E+ ET +T+ +D+ + + ++ S+ V ++ T + V +V
Sbjct: 1022 EVGETELSTQEVVDEKVSVTEEVIEEEKSVSEEVLEEGSATEEVVEEGSCT------EVV 1075
Query: 6320 AEDIFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAETEEKVGETK 6499
E+ TE V +E ++ G D + +EG EE + TE V E
Sbjct: 1076 VEEGSCTEVVVEEG--SCTEIVVEKGSDTEIVVEEGSATEIVVEE---GSATEVVVEEGS 1130
Query: 6500 PKESQAEGAEKSDDQVEDESTKKTDVEVAGLENDYPTEEAEHGDETYSTLPVVGIXXXXX 6679
E E S++ +E+E + +V GL +D + G+
Sbjct: 1131 ATEEVVEEGSVSEEMLEEEGSATEEVVEEGLSSDNVQKSK-------------GVIENVG 1177
Query: 6680 XXXXXXRAINDSASSEVSMIKEP-ADQEEKKGDDVVESNEKDFVSDILEAKRLHGDKSGE 6856
A ++S + ++ + K D E KG ++ V D+ ++ E
Sbjct: 1178 EIYSVKTAKDESMNEKIPLEKSSFVDDESFKGQGPTDNVS---VEDVNSEDIINEHTPLE 1234
Query: 6857 AEKIKEESGLAGKSLPIEEINLXXXXXXXXXXX-------XXTREIAQVLPREEILISSS 7015
KI+E LP E I E+ + +EE + +
Sbjct: 1235 ETKIEE--------LPTEYITTADIHTKGETETKYNLIYEKINEEVEKAKFQEEKITENI 1286
Query: 7016 PLSAEEQEHVISDE---KQEEREPQQDFNGSTSEKISLQ--------VEHLKDFETSKKE 7162
P+ E I E QE + + D N K++ + E++ + E E
Sbjct: 1287 PVERESVTEDIVQEPSLAQEVEQKESDTNEIEETKLANEKIIPEVSVTENVVEKEGLDTE 1346
Query: 7163 QKDETHETVXXXXXXXXXXXXXXXXXXXXXXSSEVKKDNKDARELEVGNDFVS------- 7321
+ E E++ S E+ ++ + + E V + S
Sbjct: 1347 EVLEEDESITEEIVEEEVSSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSEEIVEE 1406
Query: 7322 RDGEKEEVPHNALENEEEMNEVVASEKQISDPVGVIKKASEAEHEDPVDDIKS------- 7480
+ EE+ + EE+ E V+S +++ + G + + E +++K
Sbjct: 1407 EESSSEEIVEEEESSSEEIIEEVSSTEEVLEEEGSVTEEIVEEEVSTTEEVKDIGSVSEE 1466
Query: 7481 -NDDRDFPTEQAPKDQSDEVSADETVPKEAIGEE-LKVPSSKVLDDIQENS-------NT 7633
++ F TE+ Q + +E V E+ E+ L+ S V + +QE +
Sbjct: 1467 VLEEEGFGTEEFVGQQGSVI--EEIVETESSTEKVLEDVGSNVEEIVQEEGPVAQEIVHE 1524
Query: 7634 EAVTNFADRDLPVQNLSELIQSHQSPNQ---VEETSFEFNKAQEDKKEETV---DALITN 7795
E T ++ E+++ S ++ VEE S +E E V + LI
Sbjct: 1525 EVSTTEKHDEVDRSTTEEIVEKVGSVSEEIIVEEVSASEEIVEEGSVTEEVVEEEKLINE 1584
Query: 7796 VQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQEDIGTYVKVQVPDDEIKGDGHDSVAA 7975
V + E+ ++KE+S+ E L + E+I ++ + +EI G
Sbjct: 1585 VGETESVTEEI----VQKEVSDAEEVLGQEGSMNEEI---LEKESIVEEIVGPEGSVTEE 1637
Query: 7976 QKEETSSIEEKREVEHVKAE---MEDAIKHEVSVEEKNNTSENIDHEAAKEIEQEEGKQT 8146
+ S EE +E E V E E ++ E+ EE +E I+ A EI +E+G T
Sbjct: 1638 IVDHGSFAEEVKEEELVTEEAVQYEGSVTEEIKEEESITENEAIEESAFAEIIEEKGPNT 1697
Query: 8147 NIVXXXXXXXXXXXNQESFNNVKETDDAIDKTQPEIRDIESLSSVSKTQDKPEPEYEVPN 8326
+ + +E N V TD+ I++ + + + V + + E EV
Sbjct: 1698 DEI----VKEEGLDTEEIVNEVSVTDEVIEEEK-----LVNEQIVGEERSVTEKPVEVER 1748
Query: 8327 QQKREITNEVPSL 8365
++ E S+
Sbjct: 1749 SATEDLVEEEASV 1761
Score = 142 bits (359), Expect = 7e-32
Identities = 293/1622 (18%), Positives = 606/1622 (37%), Gaps = 66/1622 (4%)
Frame = +2
Query: 341 REPQSLNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQEED 520
+E S+NE+ +E+ ++ LE EE S + ++EE+ + + LE+E
Sbjct: 3388 KEENSVNEEVLEEEGSYTEEILE-----------EEGSYTEEILEEEGSFTEEILEEEGS 3436
Query: 521 IGNISKVLTDTTPVKVDEYDIEKSLN-SVCEEIPIKTDEVREETDSRTVETSVNGTEAEH 697
++L + + + E S N + EE +E+ EE S T G++ E
Sbjct: 3437 YN--EEILEEEGSYNEEILEEEGSYNEEILEEEGSYNEEILEEEGSATDYFVGQGSDNEE 3494
Query: 698 NATVSVEEISRN----GDNTVNETVSEDQTATD---GEPLHDVETIKREAEPFYKTVVED 856
+EE S G + NE + E+ +ATD G+ E ++ E K +
Sbjct: 3495 ----IIEEGSATDYFVGQGSDNEEIIEEGSATDYFVGQGSIIEEVLEEEGLDTEKVFENE 3550
Query: 857 AKIVNTEETTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDKEKEEDIIQNI 1036
EET + + + ++ E E E E + KE+ + + I
Sbjct: 3551 GSATEFEETESFTEVVEETESVNENILEETSIN------EVQKIESITEDIKEQLVPEEI 3604
Query: 1037 EEVQESPSVMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVT 1216
+E Q ++ + E+I+ + + E + +++ + ++E + ++ Q ++
Sbjct: 3605 KEEQLDSEEIKEEQLDSEEIKEEQLVPEEIKEEQLDSEEIKEEQLDSEEIKEEQLDSEEI 3664
Query: 1217 EAKTAETFSVQEAEILKTNINESEAHSAIGGEED--GQETKENTEPSKDLKDDKEQEDSE 1390
+ + ++ ++E +++ I E + S EE +E KE S+++K+ EQ DSE
Sbjct: 3665 KEEQLDSEEIKEEQLVPEEIKEEQLDSEEIKEEQLVPEEIKEEQLDSEEIKE--EQLDSE 3722
Query: 1391 TVK-TIISSDEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPEIETAVD 1567
+K + S+E++ + +E E + E+ ++ E I+ E E +V+
Sbjct: 3723 EIKEEQLDSEEIKEEQLDSEEIKEQKGSVNEEVVEEEGSVTEEIK--------EQEESVN 3774
Query: 1568 GESVHEIETTERVLLEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXXXXXXXXT 1747
E + E+E TE + E + + E
Sbjct: 3775 EEVLEEVEETESIKEEIVEGGIATQEIIEEESDTKEVVEEE------------------- 3815
Query: 1748 SVHESESLKENAEPVEAVKNSDGTEQISREVTVDRAKEEDIAPKTEEIQERPSESKASLE 1927
V +SE L + V + ++ EV + + E++ + + + E E +++
Sbjct: 3816 -VIDSEKLVDAGSVTGEVMPEE--VSVTDEVVEEGSTTEEVLEEQKSVNEEVVEDGLTID 3872
Query: 1928 PKEEVDHISNETEEHEHVLERDVQQCETIESEAVETKEDTQPSLDLKEDKETEEAETFKT 2107
D + + E V+E D E I E T+E + + + ED +E +
Sbjct: 3873 -----DFVGLQGSTTEEVVEEDGSAIEKILEEETATEEIVEKQVSVTEDIVEKEGSVNEE 3927
Query: 2108 VFSSDEVRSSAVQEEQFGE----HTEPCSSEIKDESHGKEESVEVKSQETVQDENTEDKH 2275
+ V +Q F E E + E+ DE +E + +++V +E E+
Sbjct: 3928 IIEEASVAEEIIQGGSFTEEIVGQEESATEEVIDEEGLISNEIEEEEEKSVTEEMIEEVE 3987
Query: 2276 DVLKVPSTESEKYQGNEPETVLV---------SNTGSYEKSEKSPSDLVLNVDK--EELN 2422
+V E E LV S T + +S +D ++ + EE+
Sbjct: 3988 EVSVDDEVEEVSVAEEIVEEELVDDEILPEELSATEDVIEEVRSVTDEIVQEESVCEEIL 4047
Query: 2423 DEKINVDQ--VDGTQIMEEPIGLDSNGAEAEQIDQNITNETEEI-------LVAKPVSLL 2575
+++++ + VD + ++ +G + + + + +++T E E+ V K S+
Sbjct: 4048 EQEVSASEEYVDDKSVTDDFVGHERSVIQDVENTESVTEEIAEVDKSVIEEAVEKQGSVT 4107
Query: 2576 D------VKSVEQMQKPKLES-PSEVSEETSKTVDXXXXXXXXXXVTLYQEGQVDGSYGL 2734
+ V ++E+++ +LES E++EE ++ + +E ++D L
Sbjct: 4108 EEKVQEGVSAIEEIE--ELESVTEEIAEEDKSVIEEAVEKQGSVTEEIVEEEELDTEEVL 4165
Query: 2735 ETKEETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKIEEKTDS 2914
E K T V + + + + ++E+ + S
Sbjct: 4166 EDKSVTGDVVEQEGSGKDESEAKESFTEEVDELKSVKEEDQETEYISREIEEESATEQHS 4225
Query: 2915 IELGEIAQEERSVTDLT-PLQEESSQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSASPS 3091
+ I +E LT ++EE S E +ET+ E EE +DEV++ SPS
Sbjct: 4226 EQELSINKEVVETESLTKDIEEEKSTTQEILEETQSVNEEIVEEERDTDEVLKE-KVSPS 4284
Query: 3092 KELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVAEE 3271
+E+ E + E V+ D + E+
Sbjct: 4285 EEVIEE---------------------QASTTEEFVE----------ERSSTDEIVEVED 4313
Query: 3272 IVDEKAKEEVPMLQIKNEDDATKIHETRVEQARDIGPSLTEICSINQNQPEEQVKEACSK 3451
+ E+ KE + E VE+ D G EI + EE ++E
Sbjct: 4314 LFTEEVKER-----------EGSVTEEIVEEGSDTG----EIVEEEGSDTEEILEEGSFN 4358
Query: 3452 EEQEKEISTNSENIV--NETYALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXXXXXXX 3625
EE +E + +E I+ + T + G ++++ T+S
Sbjct: 4359 EEIVEEEGSITEEILQGSVTEEILQGSVTEEFVGQQGSVIEEIVETESAIEERVEEESAT 4418
Query: 3626 XXXXXXXPRLDAIXXXXXXXXXXXXQD-AKIVNNEETTAHESESLKGDNHQEKNAEPVEA 3802
+ + +++ NE + E + + + V
Sbjct: 4419 EEVDERESVTEVVEEEVSSSDEVVEGSIEEVIENEGSVTEEILEHEVSADENFVGQAVSV 4478
Query: 3803 TQNLDDAEQISREVTVDTEREADITEKIEKVQEGPTVIETPTIQGEDIESETSLELKEEV 3982
+ ++ E ++ EV +TE ++E+I +V V++ E++ + EE+
Sbjct: 4479 IEEVEGTESVTEEVVEETE---SVSEEIVEVSPTENVVQQTDSVIEEVVEQKEGSFNEEI 4535
Query: 3983 D---QSSKDTEEHEHV-LERDIPQCETLKAEAVDTSTVEEAAILKTLE--TNISEPEAMH 4144
D EE E + E + Q ++ + + S+ E+ + + E +S E +
Sbjct: 4536 DIRELGDDGVEEREKISTEEVVGQDKSATGDVEEVSSTEDEEEVSSTEGLEEVSSTEGL- 4594
Query: 4145 SETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDESQGXXXXX 4324
E + + +E E V+ + V + + EE + + ++ E +
Sbjct: 4595 -EEVSNTEDVEEVSSTEDVEEGSVAENVKETKSITEEVSVEEDIITDKVSVEQEVMAEAS 4653
Query: 4325 XXXXXXTVQGESSEEKDVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEEIPSVV--- 4495
T + EE L V+ + +E +I + E+G+ E +P+ V
Sbjct: 4654 VEENILT-EVPVEEEIMTEKLSVEDKALNEKIMSEEEIVI----EDGNVHEVVPAEVSVT 4708
Query: 4496 -EGAGLDETTHNQTLLDVESVVKQSL---DTPSEEETSXXXXXXXXXXXXXXVTLHQEGR 4663
E G++ETT+N++ + E+VV + + ++ ++E H+E
Sbjct: 4709 EEIPGVEETTNNESHVKGENVVNEVVVDDNSVNDEIQFDDDSSIEIYTVDSKDVFHKEEN 4768
Query: 4664 EEGSYGLDTKDEAVSVL--ESRELGEQPQQEELCLANEQENETKLQE--EQVDKHEPTKE 4831
+ DE + + ++ ++ + E+ + + T + E+V H KE
Sbjct: 4769 YDSFREEVRSDENIHIFRKKNENFVKKIENEKSSVGHVPTEYTSKENIAEEVPSHIMFKE 4828
Query: 4832 EVSNDQQSPVEEISNEVIQVSSASLSEGPEYETVVE---AEKIGEEQVADKIQKSFETGE 5002
V+ + V+ N V +V E E ++E + EE + +++ + + E
Sbjct: 4829 NVTEEVPKEVKYEENTVEEV----FEEVTSKENIIEEAPGDINSEENIIEEVPEVVTSEE 4884
Query: 5003 IV 5008
IV
Sbjct: 4885 IV 4886
Score = 142 bits (359), Expect = 7e-32
Identities = 319/1575 (20%), Positives = 607/1575 (38%), Gaps = 110/1575 (6%)
Frame = +2
Query: 3938 EDIESETSLELKEEVDQSSKDTEEHEHVLERDIPQCETLKAEAVDTSTVEEAAILKTLET 4117
ED+E E++ +K+TE+ E + Q + L E TLE
Sbjct: 17 EDMEETEKENEIEKIMDENKETEQTEEGNTEEFVQEKELNQE--------------TLEN 62
Query: 4118 NISEPEAMHSETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEI-K 4294
I E + ++K + E ++ + N +G + + EEF + P ++ K
Sbjct: 63 EIIVDHIKEEEDTRNVKEQESVLEESPIEELPVENNIGKINEEVEEFILNEIPLEEQVPK 122
Query: 4295 DESQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQSGE--SEKYQENEPDISLVSKTENGD 4468
+ Q + SSEE V D G+ +E+ E +S E
Sbjct: 123 ELPQEEIEEIVVEELPIDEHLSSEETTVTEEDTFKGQLINEEKPVEEKSVSEEIPVEEKS 182
Query: 4469 KFEEIP----SVVEGAGLDETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXXXXX 4636
EEIP SV E ++E + ++ + E V + + P EE+
Sbjct: 183 VSEEIPVEEKSVSEEIPVEEKSVSEEIPVEEKNVSEEI--PVEEKNVSEEIPVEEKNVSE 240
Query: 4637 XVTLHQEGREEGSYGLDTKDEAVSVLESRELGEQPQQEELCLANEQENETKLQEEQVDKH 4816
+ + +E E E +E + E+ EE+ + + ++ + E V++
Sbjct: 241 EIPVEEENVSE------EIPEGGIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEE 294
Query: 4817 EPTKEEVSNDQ-QSPVEEISNEVIQVSSASLSEGPEYETV--------VEAEKIGEEQ-V 4966
P ++E +Q S E + E+I+ +EG E E++ V + I EEQ +
Sbjct: 295 MPVEDETLTEQISSEHERVPEEIIE--EKPFTEGEETESLTDEIVEEGVVTDDIPEEQII 352
Query: 4967 ADKIQ--KSFETGEIVEAHSSLPSSSEEKEHETVSEKTDD-----EKVKDAEPIG--DMR 5119
+K+Q + F TGE+ E + + ++E E+V+E+ + EKV++ E ++
Sbjct: 353 TEKVQEEEEFVTGELSE--EDIINEKVQEEDESVTEELPEEDIINEKVQEEEESAYQEIV 410
Query: 5120 ERGLDIAETTHLSLPSVDQK--------EDVDEIHIPSVALPLDEQ-------------- 5233
+ G + + L + D + ED + + + LP++E+
Sbjct: 411 QDGSVTKDVEYKELVNDDVRDKENFVIEEDPFKGQLINEGLPVEEEFVTKELPVKEESVF 470
Query: 5234 EKVTSTEKGETKSSEAEDD---KPDEHVDSSTSPMLSEKND-NETQTSKTSEDVCMQQEE 5401
E++T ++ TK E+ K + ++S T ++ E+ NE + S + + E
Sbjct: 471 EELTEEDQSVTKEIPVEEHSVFKEVDEIESVTDEIVEEEGSVNEEVEEEVSVSGEVDETE 530
Query: 5402 SGTLEVPKP----EESKEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSELVSEQDD 5569
T EV + EE +++ ++ + E S T+ T S E+V E+
Sbjct: 531 YVTEEVEETELVNEEVLKEEGSASEKVVKEEGSASEKIVEEEGSVTEETASEEIVEEEGS 590
Query: 5570 QSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDADNTLSSQLV-SETKEEHKLQAGEIL 5746
+ + E++SE + E S + + S +V E ++ E
Sbjct: 591 VTEESSSEEIVEDEGSVTE-ESSSEEIVEEEGSVIEESASEVIVEDEVSASKEIVEDEAS 649
Query: 5747 PTEIIPRES---SDEALVSMLASRE-------DDKVALQEDNCADD-VRETNDIQEERSI 5893
TE + E SDE V+ E D+ + QE + D+ V+E + EE ++
Sbjct: 650 VTEEVVEEEGAVSDEVQVTESVEDEIINQGIVDEVIVEQEASVTDEIVKEDESVIEEIAV 709
Query: 5894 SVETEESVGETKPKEHEDEIRDAHVETPTAPIILEEN--DSETL---IAEAKKGNEEINE 6058
E V ETKP + E + + VE ++E D ++ + E K +EEI +
Sbjct: 710 EETVTEVVEETKPMDEEIVDQGSVVENVEEKKTMDEEIVDQGSVVENVEEKKTMDEEIGD 769
Query: 6059 TERTVALDHEEEFVNHEAPKLEETKDEKSQEIPETAKATETTIDQTLPIGTSQADQTPSL 6238
EEE V E + E + +E +I + A TE ++Q P+ T + ++ S+
Sbjct: 770 QGSVAEKVEEEELVTEEVIEREGSINE---DIVKEASITE-EVEQIEPV-TGKVEKIESI 824
Query: 6239 VSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETVPKESFIEAPVSMLASGEDEPVTP 6418
+ +Q + ++ E + E V + + + +AS +E
Sbjct: 825 TDEIKEQLVPE-------------DIKEEQLDFEEIVAQRASVNDEKVEVASITEEV--- 868
Query: 6419 QEGDYAANTQEERHVSAETEEKVGETKPKESQAEGAE--------KSDDQVEDESTKKTD 6574
+EE+ VS E E+ G T K + E +++ +E+ES +
Sbjct: 869 --------EEEEKSVSEEVLEEEGSTTEKVVKGSSTEVVVEEQGSVTENLLEEESASQGI 920
Query: 6575 VEVAGLENDYPTEEAEHGDETYSTLPVVGIXXXXXXXXXXXRAINDSASSEVSMIKEPAD 6754
VE + ++ EE D+ E +I E +
Sbjct: 921 VE----KEEFVDEEDSVKDQN--------------VFEKEGSVTEQLVEEEKGLINEDNE 962
Query: 6755 QEE---KKGDDVVESNEKDFVSDILEAKRLHGDKSGEAEKIKEESGLAGKSLPIEEINLX 6925
+EE + +++ NE+ +D+ + + E ++EE L K L E +
Sbjct: 963 KEELITEMSEEIKSVNEEIEETDLSTEEIIKQQGLATYEFVEEEKSLTDKLLEEESV--- 1019
Query: 6926 XXXXXXXXXXXXTREIAQV-LPREEILISSSPLSAE--EQEHVISDEKQEEREPQQDFNG 7096
T+E+ + L +E++ ++ E E+E +S+E EE G
Sbjct: 1020 ------------TKEVGETELSTQEVVDEKVSVTEEVIEEEKSVSEEVLEE--------G 1059
Query: 7097 STSEKISLQVEHLKDFETSKKEQK-DETHETVXXXXXXXXXXXXXXXXXXXXXXSSEVKK 7273
S +E++ VE E +E E ++E+
Sbjct: 1060 SATEEV---VEEGSCTEVVVEEGSCTEVVVEEGSCTEIVVEKGSDTEIVVEEGSATEIVV 1116
Query: 7274 DNKDARELEVGNDFVSRD-GEKEEVPHNALENEEEMNEVVASEKQISDPV----GVIKKA 7438
+ A E+ V + + E+ V LE E E V E SD V GVI+
Sbjct: 1117 EEGSATEVVVEEGSATEEVVEEGSVSEEMLEEEGSATEEVVEEGLSSDNVQKSKGVIENV 1176
Query: 7439 SEAEHEDPVDDIKSN-----DDRDFPTEQAPKDQ--SDEVSADETVPKEAIGEELKVPSS 7597
E D N + F +++ K Q +D VS ++ ++ I E + +
Sbjct: 1177 GEIYSVKTAKDESMNEKIPLEKSSFVDDESFKGQGPTDNVSVEDVNSEDIINEHTPLEET 1236
Query: 7598 KVLDDIQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQVEETSFEFNKAQEDKKEETV 7777
K+ + E T + + + + E I +VE+ F QE+K E +
Sbjct: 1237 KIEELPTEYITTADIHTKGETETKYNLIYEKIN-----EEVEKAKF-----QEEKITENI 1286
Query: 7778 DALITNVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQ-EDIGTYVKVQVPDDEIKGD 7954
V+ + ++ + ++ +E+ ++E N++ + + + +V V ++ ++ +
Sbjct: 1287 P-----VERESVTEDIVQEPSLAQEVEQKESDTNEIEETKLANEKIIPEVSVTENVVEKE 1341
Query: 7955 GHDSVAAQKEETSSIEEKREVEHVKAE---MEDAIKHEVSVEEKNNTSENI--DHEAAKE 8119
G D+ +E+ S EE E E +E E+ E VEE+ ++SE I + E++ E
Sbjct: 1342 GLDTEEVLEEDESITEEIVEEEVSSSEEIVEEEESSSEEIVEEEESSSEEIVEEEESSSE 1401
Query: 8120 --IEQEEGKQTNIVXXXXXXXXXXXNQESFNNVKETDDAIDKTQPEIRDI--ESLSSVSK 8287
+E+EE IV ++E V T++ +++ +I E +S+ +
Sbjct: 1402 EIVEEEESSSEEIV-----EEEESSSEEIIEEVSSTEEVLEEEGSVTEEIVEEEVSTTEE 1456
Query: 8288 TQDKPEPEYEVPNQQ 8332
+D EV ++
Sbjct: 1457 VKDIGSVSEEVLEEE 1471
Score = 55.1 bits (131), Expect = 2e-05
Identities = 78/385 (20%), Positives = 158/385 (40%), Gaps = 25/385 (6%)
Frame = +2
Query: 7262 EVKKDNKDARELEVGNDFVSRDGEKEEVPHNALENEEEMNEVVASEKQISDPVGVIKKAS 7441
++ +NK+ + E GN +E V L E NE++ + + +K+
Sbjct: 30 KIMDENKETEQTEEGNT-------EEFVQEKELNQETLENEIIVDHIKEEEDTRNVKEQE 82
Query: 7442 EAEHEDPVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPKEAIGEELK--VPSSKVLDD- 7612
E P++++ ++ E+ + +E+ +E VPKE EE++ V +D+
Sbjct: 83 SVLEESPIEELPVENNIGKINEEVEEFILNEIPLEEQVPKELPQEEIEEIVVEELPIDEH 142
Query: 7613 --IQENSNTEAVT---NFADRDLPVQNLSELIQSHQSPNQVEETSFEFNKAQEDKKEE-T 7774
+E + TE T + + PV+ S S + P + + S E ++ EE
Sbjct: 143 LSSEETTVTEEDTFKGQLINEEKPVEEKS---VSEEIPVEEKSVSEEIPVEEKSVSEEIP 199
Query: 7775 VDALITNVQVQDQPKEDFEAAAIE-----KEISEQEHKLNDLTDVQEDIGTYVKVQVPDD 7939
V+ + ++ + K E +E +EI +E +++ V+E+ V ++P+
Sbjct: 200 VEEKSVSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEKNVSEEIPVEEE---NVSEEIPEG 256
Query: 7940 EIKGDGHDSVAAQKEETSSIEEK------REVEHVKAEM---EDAIKHEVSVEEKNNTSE 8092
I + E +++EK E+E V EM ++ + ++S E + E
Sbjct: 257 GIAIEDVPVDEETVTEEITVDEKIYDKLPNEIETVNEEMPVEDETLTEQISSEHERVPEE 316
Query: 8093 NIDHEAAKEIEQEEGKQTNIVXXXXXXXXXXXNQESFNNVKETDDAIDKTQPEIRDI--E 8266
I+ + E E+ E IV Q V+E ++ + E DI E
Sbjct: 317 IIEEKPFTEGEETESLTDEIVEEGVVTDDIPEEQIITEKVQEEEEFVTGELSE-EDIINE 375
Query: 8267 SLSSVSKTQDKPEPEYEVPNQQKRE 8341
+ ++ + PE ++ N++ +E
Sbjct: 376 KVQEEDESVTEELPEEDIINEKVQE 400
>ref|NP_725510.1| CG18255-PD [Drosophila melanogaster]|gi|21645322|gb|AAF58087.2|
CG18255-PD [Drosophila melanogaster]
Length = 7210
Score = 249 bits (637), Expect = 4e-64
Identities = 572/2897 (19%), Positives = 1085/2897 (36%), Gaps = 187/2897 (6%)
Frame = +2
Query: 362 EKKEDEKIILSDVTLENKKEEDTTGKPEEVSVEKPVIEEDQTEAKHSLEQEEDIGNISKV 541
+K E E ++ D ++E K EE + E+ ++K +EE + +A + ++DI S+
Sbjct: 2581 KKSETEDVV--DHSIEKKIEEPK--RSEKKDLDKEFLEEKELKASAKKQGDQDIEQKSQ- 2635
Query: 542 LTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREETDSRTVETSVNGTEAEHNATVSVEE 721
+V E EK EE P K +E+ E S E S E
Sbjct: 2636 -----KPEVSEVVAEKISEGKIEE-PKKPEEMDTEAKSEKATVLDKQVLEEKELEASAE- 2688
Query: 722 ISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNTEETTAHESK 901
+ GD V + + + + ETI+ +P V+D +I +E+ TA + +
Sbjct: 2689 --KQGDQDVEKKSQKPEVSEVVAEKISEETIEEPKKP----EVKDTEI-KSEKATALDKQ 2741
Query: 902 ILKED----NHQEEYAESVEATKN----SDAAEQSSREVTVDKEKEEDIIQNIEEVQESP 1057
+L+E + Q++ + VE S+ + E T+++ K+ ++ ++ E E
Sbjct: 2742 VLEEKELEASAQKQCDQDVEKKSQKPEVSEIVAEKISEKTIEEPKKPEV-KDTEIKSEKA 2800
Query: 1058 SVMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAKTAET 1237
+ ++ ++ +++E+ A +++++K ++ E E V + E E K E
Sbjct: 2801 TALDKQVLEEKELEASAQKQGDQDVEKKSQKPEVSEVVAEKISEETIEEPKKPEVKETEV 2860
Query: 1238 FSVQEAEILKTNI---NESEAHSAIGGEEDGQETKENTEPSKDLKDDKEQEDSETVKTII 1408
S ++A +L + E EA + G++D ++ + E S+ + + +E E K
Sbjct: 2861 KS-EKATVLDKQVLEEKELEASAQKQGDQDVEKKFQKAEVSEVVAEKISEETIEEPKKPE 2919
Query: 1409 SSDEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAK--ETGPEIETAVDGESVH 1582
D S+ + + E E + G D+ +E K++ E I + E +
Sbjct: 2920 VKDTEIKSEKATALDKQVLEEKELEASAQKQG-DQDVEKKSQKPEVSEVIAEKISEEKIE 2978
Query: 1583 EIETTERVLLEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXXXXXXXXTSVHES 1762
E + E E +E+ E E
Sbjct: 2979 EPKKPEEKETEVKSEKATVLDK-------QVLEEKELEASAQKQGDQDV---------EK 3022
Query: 1763 ESLKENAEPVEAVKNSDGT--EQISREVTVDRAKEEDIAPKTEEI-QERPSESKASLEPK 1933
S K V A K S+G E EV AK E ++ +ER E+ A +
Sbjct: 3023 RSQKPEVSEVVAEKVSEGKIEEPKKPEVKETEAKSEKATTLDMQVLEERELEASAQKQGD 3082
Query: 1934 EEVDHISNETEEHEHVLERDVQQCETIESEAVETKEDTQPSLDLKEDKETE---EAETF- 2101
++V+ S + E E + E+ I E +E E +P E+KETE E T
Sbjct: 3083 QDVEKKSQKPEVSEVIAEK-------ISEEKIE--EPKKP-----EEKETEVKSEKATVL 3128
Query: 2102 -KTVFSSDEVRSSAVQE--------EQFGEHTEPCSSEIKDESHGKEESVEVKSQETVQD 2254
K V E+ +SA ++ Q E +E + ++ + + + EVK E +
Sbjct: 3129 DKQVLEEKELEASAQKQGDQDVEKKSQKPEVSEVVAEKVSEGKIEEPKKPEVKETEVKSE 3188
Query: 2255 ENTEDKHDVLKVPSTE-SEKYQGNEPE-------TVLVSNTGSYEKSEKSPSDLVLNVDK 2410
+ T VL+ E S + QG++ L K+ S D +L +
Sbjct: 3189 KATTLDKQVLEEKELEASAQKQGDQDGKSRDDIIKTLKERLTELSKALGSSVDEILRESR 3248
Query: 2411 E---ELNDEKI-----------NVDQVDG--------TQIMEEPIGL--DSNGAEAEQID 2518
E L D+K+ V DG ++ E I L +++ AE++
Sbjct: 3249 EIVNNLEDDKVVAKHLFKLRDHIVHTYDGKRGEENKEKELFESFIELLCEASPEAAEKVK 3308
Query: 2519 QNITNE--TEEILVAKPVSLLDVKSVEQMQKPKLESPSEVSEETSKTVDXXXXXXXXXXV 2692
N E T IL + L+D ++ KP L P ++ E V
Sbjct: 3309 LNYLKEIKTNVILTKATIQLIDDSNM--FTKPSLLIPKLLNLE-------------RVAV 3353
Query: 2693 TLYQEGQVDGSYGLETKEETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXXX 2872
+ E VD ++ E+ +S+ + D T + KP
Sbjct: 3354 KIQSETYVD-----KSSEKMISLQQSLMDIFVILDD-FLDDETEVLKPKIENIKTTLLSD 3407
Query: 2873 XKTVDEKIEEKTDSIELGE----------IAQEERSVTDLTPLQEESSQPNEQEKETKLE 3022
+++K ++ G+ I +E + +T+ +E+ E + +
Sbjct: 3408 YDYIEKKDGPLLTAVINGKINVVSQHILTIIEEVKQLTENHDQKEKDVSNAEADNFADEK 3467
Query: 3023 KHEPTNEEVKSDEVIEVLS-ASPSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETV 3199
+ E EE+K E S S K +E E + +
Sbjct: 3468 REESQKEEIKDSEAKHKKSKVSEKKSIEEEKL----------------------EDKKEK 3505
Query: 3200 QTVXXXXXXXXXXXXQDHVTVAEEIVDEKA----KEEVPMLQIKNED----DATKIHETR 3355
QT + V+E+I DEKA K+EV + K + + I E +
Sbjct: 3506 QTESAIDEKSQKAEVSE--IVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEK 3563
Query: 3356 VEQARDIGPSLTEICSINQNQPEEQVKEACSKEEQEKEISTNSENIVNETYALHSVXXXX 3535
+E ++ TE +I++ + +V E S++ +++ + + V ++ A
Sbjct: 3564 LEDKKE---KQTE-SAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVL 3619
Query: 3536 XXXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQ---- 3703
L+D + T++ D +
Sbjct: 3620 EKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSETVSEKITDEKAQESQKEEVKDSEAKPK 3679
Query: 3704 DAKIVNNEETTAHESESLKGDNHQEKNAEPVEATQNLDDAEQISREVTVDTEREADITE- 3880
AK++ E + E E L+ ++ + E +Q + +E +S ++T + +E+ E
Sbjct: 3680 KAKVL---EKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEV 3736
Query: 3881 -KIEKVQEGPTVIETPTIQGEDIESETSLELKEEVDQSSKDTEEHEHVLER--DIPQCET 4051
E + V+E +I+ E +E + + +D+ S+ E E V E+ D E+
Sbjct: 3737 KDSEAKPKKAKVLEKKSIEEEKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQES 3796
Query: 4052 LKAEAVDTSTVEEAAILKTLETNISEPEAMH--SETSLDLKVDKEQKEAETVKTVI--FS 4219
K E D+ + A K LE E E + E + +D++ ++AE + V +
Sbjct: 3797 QKEEVKDSEAKPKKA--KVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKIT 3854
Query: 4220 NEVGTSDAQAEEFGEHTEPCSSEIKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQS 4399
+E + E G +P +++ ++ +++ E E+K +S
Sbjct: 3855 DEKAQESQKKEVKGSEAKPKKAKVLEKK-------------SIEEEKLEDKKEK--QTES 3899
Query: 4400 GESEKYQENEPDISLVSKTENGDKFEEIPSVVEGAGLDETTHNQTLLDVESVVKQSLDTP 4579
EK Q+ E +VS+ +K +E + E + +L+ +S+ ++ L+
Sbjct: 3900 AIDEKSQKAEVS-EIVSEKITDEKAQE-SQMEEVKDSEAKPKKAKVLEKKSIEEEKLENK 3957
Query: 4580 SEEETSXXXXXXXXXXXXXXVTLH-------QEGREEGSYGLDTKDEAVSVLESRELGEQ 4738
E++T + QE +++ + K + VLE + + E+
Sbjct: 3958 KEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEE 4017
Query: 4739 PQQEELCLANEQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGP 4918
+++ E++ E+ + +E+ K E ++ N +E + ++ S A P
Sbjct: 4018 KLEDK----KEKQTESAI-DEKSQKAEVSEIVSENITDEKAQESQKKEVKDSEAK----P 4068
Query: 4919 EYETVVEAEKIGEEQVADKIQKSFETGEIVEAHSSLPSSSE--------EKEHETVSEKT 5074
+ V+E + I EE++ DK K +T ++ S SE EK E+ E+
Sbjct: 4069 KKAKVLEKKSIEEEKLEDK--KETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEV 4126
Query: 5075 DDEKVK------------DAEPIGDMRERGLDIAETTHLSLPSVDQKEDVDEIHIPSVAL 5218
D + K + E + D +E+ T ++ QK +V EI ++
Sbjct: 4127 KDSEAKPKKAKVLEKKSIEEEKLEDKKEK------QTESAIDEKSQKAEVSEIVSENIT- 4179
Query: 5219 PLDEQEKVTSTEKGETKSSEA-------------EDDKPDEHVDSSTSPMLSEKNDNETQ 5359
EK ++K E K SEA E++K ++ + T + EK+
Sbjct: 4180 ----DEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEV 4235
Query: 5360 TSKTSEDVCMQQEESGTLEVPKPEESKEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTL 5539
+ SE + ++ + + K ++K K++ D+ + + TD+ +
Sbjct: 4236 SEIVSEKITEEKAQESQKKEVKDSKAKPKKAKVLEKKSIEEAKLEDK----KETQTDSAI 4291
Query: 5540 S--------SELVSEQDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDADNTLSSQ 5695
SE+VSE+ A +A +E +N Q
Sbjct: 4292 DEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLENKKEKQ 4351
Query: 5696 LVSETKEE-HKLQAGEILPTEIIPRESSDEALVSMLASRED-------DKVALQEDNCAD 5851
S E+ K + EI+ +I ++ + + S +K +++E+ D
Sbjct: 4352 TESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLED 4411
Query: 5852 -DVRETNDIQEERSISVETEESVGE--TKPKEHE---DEIRDAHVETPTAPIILEENDSE 6013
++T +E+S E E V E T K E +E++D+ + A ++ +++
Sbjct: 4412 KKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKS--- 4468
Query: 6014 TLIAEAKKGNEEINETERTVALDHEEEFVNHEAPKLEETKDEKSQEI-----------PE 6160
I EAK E+ ET+ A+D + + E+ DEK+QE P+
Sbjct: 4469 --IEEAKL--EDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPK 4524
Query: 6161 TAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFST 6340
AK E + + + QT S + +K + + Q E++ +
Sbjct: 4525 KAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDS 4584
Query: 6341 ETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAETEEKVGETKPKESQAE 6520
E PK++ + S+ ++ Q ++ VS EK+ + K +ESQ E
Sbjct: 4585 EAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQME 4644
Query: 6521 GAEKSDDQVEDESTK---KTDVEVAGLENDYPTEEAEHGDETYSTLPVVGIXXXXXXXXX 6691
E D + + + K K +E A LE+ T+ DE V I
Sbjct: 4645 --EVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEI--------- 4693
Query: 6692 XXRAINDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDILEAKRLHGDKSGEAEKIK 6871
+++ + E + +E + ++V +S K + +LE K + +K + ++ +
Sbjct: 4694 ----VSEKITDEKA--------QESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQ 4741
Query: 6872 EESGLAGKSLPIEEINLXXXXXXXXXXXXXTREIAQVLPREEILIS-SSPLSAEE----- 7033
ES + KS E + T E AQ ++E+ S + P A+
Sbjct: 4742 TESAIDEKSQKAEVSEI--------VSEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKS 4793
Query: 7034 -QEHVISDEKQEERE---PQQDFNGSTSEKISLQVEHLKDFETSKKEQKDETHETVXXXX 7201
+E + D+K+++ E ++ SE +S ++ K E+ KKE KD +
Sbjct: 4794 IEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKP----- 4848
Query: 7202 XXXXXXXXXXXXXXXXXXSSEVKKDNKDARELEVGNDFVSRDGEKEEVPHNALENEEEMN 7381
E K +NK ++ E D S+ E E+ + +E+
Sbjct: 4849 --------KKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQE 4900
Query: 7382 EVVASEKQISDPVGVIKKASEAEHEDPVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPK 7561
+ +K++ D KKA E + +++ K D ++ TE A ++ + ETV
Sbjct: 4901 ---SQKKEVKDSEAKPKKAKVLEKKS-IEEEKLEDKKEKQTESAIDEKFQKAEVSETV-- 4954
Query: 7562 EAIGEELKVPSSKVLDDIQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQVEETSFEF 7741
S K+ D+ E S E V + + + L + + +E E
Sbjct: 4955 ----------SEKITDEKAEESRKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTES 5004
Query: 7742 ---NKAQEDKKEETVDALITNVQVQD-QPKEDFEAAAIEKEISEQEHKLNDLTDVQEDIG 7909
K+Q+ + ETV IT+ + Q+ Q KE ++ A K+ E K ++ + E
Sbjct: 5005 AIDEKSQKAEVSETVSEKITDEKAQESQKKEVKDSEAKPKKAKILEKKSIEIEKLDEKKE 5064
Query: 7910 TYVKVQVPDDEIKGDGHDSVAAQKEETSSIEEKREVEHVKAEMEDA---IKHEVSVEEKN 8080
+ +V D +V + I E++ E K E++D+ K +E+K+
Sbjct: 5065 KQTETKVATD----TKSQTVEVSEIVLEKISEEKAEESQKVELKDSEAKSKKAKVLEKKS 5120
Query: 8081 NTSENIDHEAAKEIEQEEGKQTNIVXXXXXXXXXXXNQESFNNVKETDDAIDKTQPEIRD 8260
E +D K Q+E TN E+ + V E ++ EI+
Sbjct: 5121 TLKEKLDENDKK---QKEDGATN----------KSQKAEAADVVPE--KISEEKVAEIKT 5165
Query: 8261 IESLSSVSKTQDKPEPEYEVPNQQKREITNEVPSLENSXXXXXXXXXXXXXXNTKDLFSV 8440
E + S +K++ P E + K ++ VP ++N +DL V
Sbjct: 5166 PEPMDSKAKSKPDGLPADEKSHGAK--VSESVP-VKNEAEKTDQLSAKKPTVLDEDL--V 5220
Query: 8441 VKETEPTLKEPARKSLS 8491
V + +P L E S+S
Sbjct: 5221 VPKRKPYLAEQTADSIS 5237
Score = 215 bits (547), Expect = 1e-53
Identities = 367/1807 (20%), Positives = 723/1807 (39%), Gaps = 112/1807 (6%)
Frame = +2
Query: 356 LNEKKEDEKIILSDVTLENKKEEDTTGKPEEVSV-EKPVIEEDQTEAKHSLEQEEDIGNI 532
++EK DEK S + K+ + + KP++ V EK IEE++ E K + E I
Sbjct: 3524 VSEKITDEKAQES----QKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEK 3579
Query: 533 SKVLTDTTPVKVDEYDIEKSLNSVCEEIPIKTDEVREET----DSRTVETSVNGTEAEHN 700
S+ + + + ++ EK+ S +E+ K E + + + +++E + + E
Sbjct: 3580 SQK-AEVSEIVSEKITDEKAQESQKKEV--KDSEAKPKKAKVLEKKSIEEAKLEDKKETQ 3636
Query: 701 ATVSVEEISRNGDNTVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNTEE 880
+++E S+ + V+ETVSE T + E EA+P + AK++ E+
Sbjct: 3637 TDSAIDEKSQKAE--VSETVSEKITDEKAQESQKEEVKDSEAKP------KKAKVL--EK 3686
Query: 881 TTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDK--EKEEDIIQNIEEVQES 1054
+ E K+ + Q E A E ++ ++ +E S ++T +K E ++ +++ E +
Sbjct: 3687 KSIEEEKLEDKKEKQTESAID-EKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKK 3745
Query: 1055 PSVMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAKTAE 1234
V+E +I+ E +E K + +D+ ++ E E V + E+ E K +E
Sbjct: 3746 AKVLEKKSIEEEKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSE 3805
Query: 1235 TFSVQEAEILKTNINESEAHSAIGGEEDGQETKENTEPSKDLKDDKEQEDSETVKTIISS 1414
+ + K +I E + ED +E + TE + D K K E SE V I+
Sbjct: 3806 AKPKKAKVLEKKSIEEEKL-------EDKKE--KQTESAIDEKSQKA-EVSEIVSEKITD 3855
Query: 1415 DEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPEIETAVDGESVHEIET 1594
++ + S + EV G +P +++ + + +E +E K ++ + E+A+D +S + E
Sbjct: 3856 EKAQESQ-KKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEK---QTESAIDEKS-QKAEV 3910
Query: 1595 TERVLLEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXXXXXXXXTSVHESESLK 1774
+E V + S +KA+ + +
Sbjct: 3911 SEIVSEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKS 3970
Query: 1775 ENAEPVEAVKNSDGTEQISREVTVDRAKEEDIAPKTEEIQERPSESKASLEPKEE----- 1939
+ AE E V T++ ++E K+ + PK ++ E+ S + LE K+E
Sbjct: 3971 QKAEVSEIVSEKI-TDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTES 4029
Query: 1940 -VDHISNETEEHEHVLE------------RDVQQCE------------TIESEAVETKED 2044
+D S + E E V E ++V+ E +IE E +E K++
Sbjct: 4030 AIDEKSQKAEVSEIVSENITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKE 4089
Query: 2045 TQPSLDLKEDKETEEAETFKTVFSSDEVRSSAVQEEQFGEHTEPCSSEIKDESHGKEESV 2224
TQ D D+++++AE + V S+++ QE Q E+KD S K +
Sbjct: 4090 TQ--TDSAIDEKSQKAEVSEIV--SEKITDEKAQESQ--------KEEVKD-SEAKPKKA 4136
Query: 2225 EVKSQETVQDENTEDKHDVLKVPSTESEKYQGNEPETVLVSNTGSYEKSEKSPSDLVLN- 2401
+V ++++++E EDK + + S EK Q E + VS + EK+++S V +
Sbjct: 4137 KVLEKKSIEEEKLEDKKE-KQTESAIDEKSQKAEVSEI-VSENITDEKAQESQKKEVKDS 4194
Query: 2402 ---------VDKEELNDEKINVDQVDGTQIMEEPIGLDSNGAE-AEQIDQNITNETEEIL 2551
++K+ + +EK+ + T E I S AE +E + + IT E +
Sbjct: 4195 EAKPKKAKVLEKKSIEEEKLEDKKEKQT---ESAIDEKSQKAEVSEIVSEKITEEKAQES 4251
Query: 2552 VAKPV--SLLDVKSVEQMQKPKLESPSEVSEETSKTVDXXXXXXXXXXVTLYQEGQVDGS 2725
K V S K + ++K +E ++ ++T V+ ++
Sbjct: 4252 QKKEVKDSKAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDE 4311
Query: 2726 YGLETKEETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKIEEK 2905
E+++E V +S+ + K K + I+EK
Sbjct: 4312 KAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLENK------------KEKQTESAIDEK 4359
Query: 2906 TDSIELGEIAQEERSVTDLTPLQEESSQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSAS 3085
+ E+ EI E+ + +E +Q Q+KE K + +P +V + IE
Sbjct: 4360 SQKAEVSEIVSEK--------ITDEKAQ-ESQKKEVKGSEAKPKKAKVLEKKSIEEEKLE 4410
Query: 3086 PSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVA 3265
KE + E+ + V+
Sbjct: 4411 DKKEKQTESAIDEKSQKAEVSE-----------------------------------IVS 4435
Query: 3266 EEIVDEKA----KEEVPMLQIKNEDDATKIHETRVEQARDIGPSLTEICS-INQNQPEEQ 3430
E+I DEKA KEEV + K + A + + +E+A+ T+ S I++ + +
Sbjct: 4436 EKITDEKAQESQKEEVKDSEAKPK-KAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAE 4494
Query: 3431 VKEACSKEEQEKEISTNSENIVNETYALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXX 3610
V E S++ +++ + + V ++ A L+D + T++
Sbjct: 4495 VSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEK 4554
Query: 3611 XXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQ----DAKIVNNEETTAHESESLKGDNHQE 3778
D + AK++ E + E E L+ ++
Sbjct: 4555 SQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVL---EKKSIEEEKLEDKKEKQ 4611
Query: 3779 KNAEPVEATQNLDDAEQISREVTVDTEREADITE--KIEKVQEGPTVIETPTIQGEDIES 3952
+ E +Q + +E +S ++T + +E+ + E E + V+E +I+ +E
Sbjct: 4612 TESAIDEKSQKAEVSEIVSEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEAKLED 4671
Query: 3953 ETSLELKEEVDQSSKDTEEHEHVLER--DIPQCETLKAEAVDTSTVEEAAILKTLETNIS 4126
+ + +D+ S+ E E V E+ D E+ K E D+ + A K LE
Sbjct: 4672 KKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKA--KVLEKKSI 4729
Query: 4127 EPEAMHSETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDESQ 4306
E E + DK++K+ E+ + +AE +E + E ESQ
Sbjct: 4730 EEEKLE---------DKKEKQTESA--------IDEKSQKAEVSEIVSEKITDEKAQESQ 4772
Query: 4307 GXXXXXXXXXXXTVQGESSEEKDVNMLDVQSGESEKYQ---ENEPDISLVSKTENGDKFE 4477
V+G ++ K +L+ +S E EK + E + + ++ K++ + E
Sbjct: 4773 ----------KKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSE 4822
Query: 4478 EIPSVVEGAGLDETTHNQT-----------LLDVESVVKQSLDTPSEEETSXXXXXXXXX 4624
+ + E+ + +L+ +S+ ++ L+ E++T
Sbjct: 4823 IVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQK 4882
Query: 4625 XXXXXVTLH-------QEGREEGSYGLDTKDEAVSVLESRELGEQPQQEELCLANEQENE 4783
+ QE +++ + K + VLE + + E+ +++ E +
Sbjct: 4883 AEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAID 4942
Query: 4784 TKLQEEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQ 4963
K Q+ +V E E++++++ EE E ++ S A P+ V+E + I EE+
Sbjct: 4943 EKFQKAEVS--ETVSEKITDEK---AEESRKEEVKDSEAK----PKKAKVLEKKSIEEEK 4993
Query: 4964 VADKIQKSFETGEIVEAHSSLPSSSEEKE-HETVSEKTDDEKVKDAE----PIGDMRERG 5128
+ DK +K E S++ S++ E ETVSEK DEK ++++ + + +
Sbjct: 4994 LEDKKEKQTE--------SAIDEKSQKAEVSETVSEKITDEKAQESQKKEVKDSEAKPKK 5045
Query: 5129 LDIAETTHLSLPSVDQKED------------VDEIHIPSVALPLDEQEKVTSTEKGETKS 5272
I E + + +D+K++ + + + L +EK ++K E K
Sbjct: 5046 AKILEKKSIEIEKLDEKKEKQTETKVATDTKSQTVEVSEIVLEKISEEKAEESQKVELKD 5105
Query: 5273 SEAEDDKPDEHVDSSTSPMLSEKND---------NETQTSKTSEDV--CMQQEESGTLEV 5419
SEA+ K ST ++ND N++Q ++ ++ V + +E+ ++
Sbjct: 5106 SEAKSKKAKVLEKKSTLKEKLDENDKKQKEDGATNKSQKAEAADVVPEKISEEKVAEIKT 5165
Query: 5420 PKPEESK 5440
P+P +SK
Sbjct: 5166 PEPMDSK 5172
Score = 205 bits (521), Expect = 1e-50
Identities = 463/2358 (19%), Positives = 904/2358 (37%), Gaps = 129/2358 (5%)
Frame = +2
Query: 236 KKP--KN*NAKMEKRQRLSRF*MTVRSLKMIKNLLSFREPQSLNEKKEDEKIILSDVTLE 409
KKP K K EK L + + + L+ ++ + ++K E +++ V+ E
Sbjct: 3111 KKPEEKETEVKSEKATVLDKQVLEEKELEASAQKQGDQDVEKKSQKPEVSEVVAEKVS-E 3169
Query: 410 NKKEEDTTGKPEEVSV--------EKPVIEEDQTEAKHSLEQEEDIGNISKVLTDTTPVK 565
K EE + +E V +K V+EE + EA + ++D G + T +
Sbjct: 3170 GKIEEPKKPEVKETEVKSEKATTLDKQVLEEKELEASAQKQGDQD-GKSRDDIIKTLKER 3228
Query: 566 VDEYDIEKSLNSVCEEIPIKTDE-VREETDSRTVETSVNGTEAEHNATVSVEEISRNGDN 742
+ E + K+L S +EI ++ E V D + V + T + N +
Sbjct: 3229 LTE--LSKALGSSVDEILRESREIVNNLEDDKVVAKHLFKLRDHIVHTYDGKRGEENKEK 3286
Query: 743 TVNETVSE-----DQTATDGEPLHDVETIKR-------------EAEPFYKTVVEDAKIV 868
+ E+ E A + L+ ++ IK ++ F K + K++
Sbjct: 3287 ELFESFIELLCEASPEAAEKVKLNYLKEIKTNVILTKATIQLIDDSNMFTKPSLLIPKLL 3346
Query: 869 NTEETTAHESKILKEDNHQEEYAESVEATKNSDAAEQS--SREVTVDKEKEEDI----IQ 1030
N E D E+ ++ + E V K K E+I +
Sbjct: 3347 NLERVAVKIQSETYVDKSSEKMISLQQSLMDIFVILDDFLDDETEVLKPKIENIKTTLLS 3406
Query: 1031 NIEEVQESPSVMESPTIQGE-DIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSET 1207
+ + +++ + + I G+ ++ S+ L EE+ ++T++ +++E +DV +++
Sbjct: 3407 DYDYIEKKDGPLLTAVINGKINVVSQHILTIIEEVKQLTENHDQKE----KDVSNAEADN 3462
Query: 1208 LVTEAKTA---ETFSVQEAEILKTNINESEAHSAIGGEEDGQETKEN-TEPSKDLKDDKE 1375
E + E EA+ K+ ++E ++ EE ++ KE TE + D K K
Sbjct: 3463 FADEKREESQKEEIKDSEAKHKKSKVSEKKSIE----EEKLEDKKEKQTESAIDEKSQKA 3518
Query: 1376 QEDSETVKTIISSDEVRSSDVQAEVFGEHTEPCSSEIKDDRHGRDESIEVKAKETGPEIE 1555
E SE V I+ ++ + S + EV G +P +++ + + +E +E K ++ + E
Sbjct: 3519 -EVSEIVSEKITDEKAQESQ-KKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEK---QTE 3573
Query: 1556 TAVDGESVHEIETTERVLLEAXXXXXXXXXXXXXXPSLNAIEKAETXXXXXXXXXXXXXX 1735
+A+D +S + E +E V + S +KA+
Sbjct: 3574 SAIDEKS-QKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEAKLEDK 3632
Query: 1736 XXXTSVHESESLKENAEPVEAVKNSDGTEQISREVTVDRAKEEDIAPKTEEIQERPSESK 1915
+ + + AE E V T++ ++E + K+ + PK ++ E+ S +
Sbjct: 3633 KETQTDSAIDEKSQKAEVSETVSEKI-TDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEE 3691
Query: 1916 ASLEPKEE------VDHISNETEEHEHVLER------------------------DVQQC 2005
LE K+E +D S + E E V E+ V +
Sbjct: 3692 EKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEK 3751
Query: 2006 ETIESEAVETKEDTQPSLDLKEDKETEEAETFKTVFSSDEVRSSAVQEEQFGEHTEPCSS 2185
++IE E +E K++TQ D D+++++AE + V S+++ QE Q
Sbjct: 3752 KSIEEEKLEDKKETQ--TDSAIDEKSQKAEVSEIV--SEKITDEKAQESQ--------KE 3799
Query: 2186 EIKDESHGKEESVEVKSQETVQDENTEDKHDVLKVPSTESEKYQGNEPETVLVSNTGSYE 2365
E+KD S K + +V ++++++E EDK + + S EK Q E + VS + E
Sbjct: 3800 EVKD-SEAKPKKAKVLEKKSIEEEKLEDKKE-KQTESAIDEKSQKAEVSEI-VSEKITDE 3856
Query: 2366 KSEKSPSDLVLN----------VDKEELNDEKINVDQVDGTQIMEEPIGLDSNGAE-AEQ 2512
K+++S V ++K+ + +EK+ + T E I S AE +E
Sbjct: 3857 KAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQT---ESAIDEKSQKAEVSEI 3913
Query: 2513 IDQNITNE------TEEI--LVAKP--VSLLDVKSVEQMQKPKLESPSEVSEETSKTVDX 2662
+ + IT+E EE+ AKP +L+ KS+E+ KLE+ E ++T +D
Sbjct: 3914 VSEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEE---EKLENKKE--KQTESAIDE 3968
Query: 2663 XXXXXXXXXVTLYQEGQVDGSYGLETKEETVSVXXXXXXXXXXXXXRSVIDPTPLQKPTX 2842
+ ++ E++++ V +S+ + K
Sbjct: 3969 KSQKAEVSEIV---SEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDK--- 4022
Query: 2843 XXXXXXXXXXXKTVDEKIEEKTDSIELGEIAQEERSVTDLTPLQEESSQPNEQEKETKLE 3022
K + I+EK+ E+ EI E ++TD E +Q Q+KE K
Sbjct: 4023 ---------KEKQTESAIDEKSQKAEVSEIVSE--NITD------EKAQ-ESQKKEVKDS 4064
Query: 3023 KHEPTNEEVKSDEVIEVLSASPSKELEGETVVXXXXXXXXXXXXXXXXXXXXXXSLETVQ 3202
+ +P +V + IE KE + ++ + E +
Sbjct: 4065 EAKPKKAKVLEKKSIEEEKLEDKKETQTDSAI-----------------DEKSQKAEVSE 4107
Query: 3203 TVXXXXXXXXXXXXQDHVTVAEEIVDEKAKEEVPMLQIKNEDDATKIH---ETRVEQARD 3373
V Q EE+ D +AK + + K + K+ E + E A D
Sbjct: 4108 IVSEKITDEKAQESQ-----KEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAID 4162
Query: 3374 IGPSLTEICSI-NQNQPEEQVKEACSKEEQEKEISTNSENIVNETYALHSVXXXXXXXXX 3550
E+ I ++N +E+ +E+ KE ++ E ++ +
Sbjct: 4163 EKSQKAEVSEIVSENITDEKAQESQKKEVKDSEAKPKKAKVLEK-------------KSI 4209
Query: 3551 NGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLDAIXXXXXXXXXXXXQDAKIVNNEE 3730
E L+D + K ++ AK +
Sbjct: 4210 EEEKLED-KKEKQTESAIDEKSQKAEVSEIVSEKITEEKAQESQKKEVKDSKAKPKKAKV 4268
Query: 3731 TTAHESESLKGDNHQEKNAEPV--EATQNLDDAEQISREVTVDTEREADITEKIEKVQEG 3904
E K ++ +E + E +Q + +E +S ++T + +E+ E+++ +
Sbjct: 4269 LEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQ-KEEVKDSEAK 4327
Query: 3905 P---TVIETPTIQGEDIESETSLELKEEVDQSSKDTEEHEHVLER--DIPQCETLKAEAV 4069
P V+E +I+ E +E++ + + +D+ S+ E E V E+ D E+ K E
Sbjct: 4328 PKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVK 4387
Query: 4070 DTSTVEEAAILKTLETNISEPEAMH--SETSLDLKVDKEQKEAETVKTVIFSNEVGTSDA 4243
+ + A K LE E E + E + +D++ ++AE + I S ++ A
Sbjct: 4388 GSEAKPKKA--KVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEV--SEIVSEKITDEKA 4443
Query: 4244 QAEEFGEHTEPCSSEIKDESQGXXXXXXXXXXXTVQGESSEEKDVNMLDVQSGESEKYQE 4423
Q E E+KD S+ +++ E+K D S EK Q+
Sbjct: 4444 Q--------ESQKEEVKD-SEAKPKKAKVLEKKSIEEAKLEDKKETQTD--SAIDEKSQK 4492
Query: 4424 NEPDISLVSKTENGDKFEEIPSVVEGAGLDETTHNQTLLDVESVVKQSLDTPSEEETSXX 4603
E +VS+ +K +E E + +L+ +S+ + L+ E +T
Sbjct: 4493 AEVS-EIVSEKITDEKAQE-SQKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSA 4550
Query: 4604 XXXXXXXXXXXXVTLH-------QEGREEGSYGLDTKDEAVSVLESRELGEQPQQEELCL 4762
+ QE ++E + K + VLE + + E+ +++
Sbjct: 4551 IDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEK 4610
Query: 4763 ANEQENETKLQEEQVDKHEPTKEEVSNDQQSPVEEISNEVIQVSSASLSEGPEYE--TVV 4936
E + K Q+ +V + K Q+S +EE+ + + A + E E +
Sbjct: 4611 QTESAIDEKSQKAEVSEIVSEKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEAKLE 4670
Query: 4937 EAEKIGEEQVADKIQKSFETGEIVEAHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIGDM 5116
+ ++ + D+ + E EIV + + E ++ E + +K K E
Sbjct: 4671 DKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIE 4730
Query: 5117 RERGLDIAE-TTHLSLPSVDQKEDVDEIHIPSVALPLDEQEKVTSTEKGETKSSEA---- 5281
E+ D E T ++ QK +V EI + EK ++K E K SEA
Sbjct: 4731 EEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKIT-----DEKAQESQKKEVKGSEAKPKK 4785
Query: 5282 ---------EDDKPDEHVDSSTSPMLSEKNDNETQTSKTSEDVCMQQEESGTLEVPKPEE 5434
E++K ++ + T + EK+ + SE + ++ + + K E
Sbjct: 4786 AKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSE 4845
Query: 5435 SKEDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSELVSEQDDQSPXXXXXXXXXXXX 5614
+K K++ + IE +N + S D++S
Sbjct: 4846 AKPKKAKVL------------EKKSIEEEKLENKKEKQTESAIDEKSQKAEVSEIVSEKI 4893
Query: 5615 XAHDVEATSERNLPVETSDADNTLSSQLVSETKEEHKLQAGEILPTEIIPRESSDEALVS 5794
D +A + V+ S+A + L ++ EE KL+ + TE E +A VS
Sbjct: 4894 T--DEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKFQKAEVS 4951
Query: 5795 MLASRE--DDKVALQEDNCADDVRETNDIQEERSISVETEESVGETKPKEHEDEIRDAHV 5968
S + D+K E++ ++V+++ + + V ++S+ E K ++ +++ ++ +
Sbjct: 4952 ETVSEKITDEKA---EESRKEEVKDSE--AKPKKAKVLEKKSIEEEKLEDKKEKQTESAI 5006
Query: 5969 ETPTAPIILEENDSETLIAEAKKGNEEINETERTVALDHEEEFVNHEAPKLEETKDEKSQ 6148
+ + + E SE I + K + E + + A + + + ++ ++E+ DEK +
Sbjct: 5007 DEKSQKAEVSETVSEK-ITDEKAQESQKKEVKDSEAKPKKAKILEKKSIEIEKL-DEKKE 5064
Query: 6149 EIPETAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAED 6328
+ ET AT+T SQ + +V +K + + + KV+ +D
Sbjct: 5065 KQTETKVATDT---------KSQTVEVSEIVLEKISEEKAE----------ESQKVELKD 5105
Query: 6329 IFSTETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAETEEKVGETKPKE 6508
+E K++ + S L DE Q+ D A N ++ + EK+ E K E
Sbjct: 5106 ---SEAKSKKAKVLEKKSTLKEKLDENDKKQKEDGATNKSQKAEAADVVPEKISEEKVAE 5162
Query: 6509 SQAEGAEKSDDQVEDESTKKTDVEVAGLENDYPTEEAEHGDETYSTLPVVGIXXXXXXXX 6688
K+ + ++ ++ K D GL P +E HG + ++PV
Sbjct: 5163 I------KTPEPMDSKAKSKPD----GL----PADEKSHGAKVSESVPVK---------- 5198
Query: 6689 XXXRAINDSASSEVSMIKEPADQEEKKGDDVVESNEKDFVSDILEAKRLHGDKSGEAEKI 6868
N++ ++ K+P +E D VV + ++ L KS ++E
Sbjct: 5199 ------NEAEKTDQLSAKKPTVLDE---DLVVPKRKPYLAEQTADSISLQTYKSMDSEYK 5249
Query: 6869 KEESGLAGKSLPIEEINL 6922
+ + K P +I L
Sbjct: 5250 DRKESRSAKRKPTVDIQL 5267
Score = 204 bits (518), Expect = 3e-50
Identities = 348/1779 (19%), Positives = 678/1779 (37%), Gaps = 78/1779 (4%)
Frame = +2
Query: 3266 EEIVDEKAKEEVPMLQIKNEDDATKIHETRVEQARDIGPSLTEICSINQNQPEEQVKEAC 3445
EEI D +AK + + K + K+ + + +Q +I++ + +V E
Sbjct: 3474 EEIKDSEAKHKKSKVSEKKSIEEEKLEDKKEKQTES---------AIDEKSQKAEVSEIV 3524
Query: 3446 SKEEQEKEISTNSENIVNETYALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXXXXXXX 3625
S++ +++ + + V + A E L+D + K
Sbjct: 3525 SEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLED-KKEKQTESAIDEKSQKA 3583
Query: 3626 XXXXXXXPRLDAIXXXXXXXXXXXXQDAKIVNNEETTAHESESLKGDNHQEKNAEPV--E 3799
++ +AK + E K ++ +E + E
Sbjct: 3584 EVSEIVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDE 3643
Query: 3800 ATQNLDDAEQISREVTVDTEREADITEKIEKVQEGPT---VIETPTIQGEDIESETSLEL 3970
+Q + +E +S ++T + +E+ E+++ + P V+E +I+ E +E + +
Sbjct: 3644 KSQKAEVSETVSEKITDEKAQESQ-KEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQT 3702
Query: 3971 KEEVDQSSKDTEEHEHVLER--DIPQCETLKAEAVDTSTVEEAAILKTLETNISEPEAMH 4144
+ +D+ S+ E E V E+ D E+ K E D+ + A K LE E E +
Sbjct: 3703 ESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKA--KVLEKKSIEEEKLE 3760
Query: 4145 S--ETSLDLKVDKEQKEAETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDESQGXXX 4318
ET D +D++ ++AE + V S ++ AQ + E+KD S+
Sbjct: 3761 DKKETQTDSAIDEKSQKAEVSEIV--SEKITDEKAQESQ--------KEEVKD-SEAKPK 3809
Query: 4319 XXXXXXXXTVQGESSEEKDVNMLDVQSGESEKYQENEPDISLVSKTENGDKFEEIPSVVE 4498
+++ E E+K +S EK Q+ E +VS+ +K +E E
Sbjct: 3810 KAKVLEKKSIEEEKLEDKKEKQ--TESAIDEKSQKAEVS-EIVSEKITDEKAQESQKK-E 3865
Query: 4499 GAGLDETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXXXXXXVTLH-------QE 4657
G + +L+ +S+ ++ L+ E++T + QE
Sbjct: 3866 VKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQE 3925
Query: 4658 GREEGSYGLDTKDEAVSVLESRELGEQPQQEELCLANEQENETKLQEEQVDKHEPTKEEV 4837
+ E + K + VLE + + E+ + + E + K Q+ +V + K
Sbjct: 3926 SQMEEVKDSEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAEVSEIVSEKITD 3985
Query: 4838 SNDQQSPVEEISNEVIQVSSASLSEGPEYETVV---EAEKIGEEQVADKIQKSFETGEIV 5008
Q+S +E+ + + A + E E + EK E + +K QK+ E EIV
Sbjct: 3986 EKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKA-EVSEIV 4044
Query: 5009 EAHSSLPSSSEEKEHETVSEKTDDEKVKDAEPIGDMRERGLDIAET-THLSLPSVDQKED 5185
+ + + E ++ E + +K K E E+ D ET T ++ QK +
Sbjct: 4045 SENITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKETQTDSAIDEKSQKAE 4104
Query: 5186 VDEIHIPSVALPLDEQEKVTSTEKGETKSSEA-------------EDDKPDEHVDSSTSP 5326
V EI + EK ++K E K SEA E++K ++ + T
Sbjct: 4105 VSEIVSEKIT-----DEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTES 4159
Query: 5327 MLSEKNDNETQTSKTSEDVCMQQEESGTLEVPKPEESKEDKSQXXXXXXXXXXXXXD--- 5497
+ EK+ + SE++ ++ + + K E+K K++ D
Sbjct: 4160 AIDEKSQKAEVSEIVSENITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKE 4219
Query: 5498 -QTLPIETSHTDNTLSSELVSEQDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVETSDA 5674
QT + SE+VSE+ + A +A +E +
Sbjct: 4220 KQTESAIDEKSQKAEVSEIVSEKITEEKAQESQKKEVKDSKAKPKKAKVLEKKSIEEAKL 4279
Query: 5675 DNTLSSQLVSETKEE-HKLQAGEILPTEIIP---RESSDEALVSMLASREDDKV----AL 5830
++ +Q S E+ K + EI+ +I +ES E + A + KV ++
Sbjct: 4280 EDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSI 4339
Query: 5831 QEDNCADDV-RETNDIQEERSISVETEESVGE--TKPKEHED---EIRDAHVETPTAPII 5992
+E+ + ++T +E+S E E V E T K E E++ + + A ++
Sbjct: 4340 EEEKLENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVL 4399
Query: 5993 LEENDSETLIAEAKKGNEE--INETERTVALDH--EEEFVNHEAPKLEETKDEKSQEIPE 6160
+++ E + + K+ E I+E + + E+ + +A + ++ + + S+ P+
Sbjct: 4400 EKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPK 4459
Query: 6161 TAKATETTIDQTLPIGTSQADQTPSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFST 6340
AK E + + + QT S + +K + + Q E++ +
Sbjct: 4460 KAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDS 4519
Query: 6341 ETVPKESFIEAPVSMLASGEDEPVTPQEGDYAANTQEERHVSAETEEKVGETKPKESQAE 6520
E PK++ + S+ + ++ Q ++ VS EK+ + K +ESQ E
Sbjct: 4520 EAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKAQESQKE 4579
Query: 6521 GAEKSDDQVEDESTK---KTDVEVAGLENDYPTEEAEHGDETYSTLPVVGIXXXXXXXXX 6691
E D + + + K K +E LE+ + DE V I
Sbjct: 4580 --EVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEK 4637
Query: 6692 XXRA----INDS-ASSEVSMIKEPADQEEKKGDD---------VVESNEKDFVSDILEAK 6829
+ + DS A + + + E EE K +D + E ++K VS+I+ ++
Sbjct: 4638 AQESQMEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIV-SE 4696
Query: 6830 RLHGDKSGEAEK--IKEESGLAGKSLPIEEINLXXXXXXXXXXXXXTREIAQVLPREEIL 7003
++ +K+ E++K +K+ K+ +E+ ++ I + + E+
Sbjct: 4697 KITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEV- 4755
Query: 7004 ISSSPLSAEEQEHVISDEKQEEREPQQDFNGSTSEKISLQVEHLKDFETSKKEQKDE--T 7177
+E I+DEK +E + +++ GS ++ +V K E K E K E T
Sbjct: 4756 -------SEIVSEKITDEKAQESQ-KKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQT 4807
Query: 7178 HETVXXXXXXXXXXXXXXXXXXXXXXSSEVKKDNKDARELEVGNDFVSRDGEKEEVPHNA 7357
+ KK+ KD+ ++ EK+ +
Sbjct: 4808 ESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSE----AKPKKAKVLEKKSIEEEK 4863
Query: 7358 LENEEEMNEVVASEKQISDPVGVIKKASEAEHEDPVDDIKSNDDRDFPTEQAPKDQSDEV 7537
LEN++ EKQ + +K+ +AE V +I S D E+A + Q EV
Sbjct: 4864 LENKK--------EKQTESAID--EKSQKAE----VSEIVSEKITD---EKAQESQKKEV 4906
Query: 7538 SADETVPKEAIGEELKVPSSKVLDDIQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQ 7717
E PK+A E K + L+D +E A+ D +SE + + +
Sbjct: 4907 KDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAI----DEKFQKAEVSETVSEKITDEK 4962
Query: 7718 VEETSFEFNKAQEDKKEETVDALITNVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQ 7897
EE+ E K E K ++ ++ ++++ ED + E I E+ K +V
Sbjct: 4963 AEESRKEEVKDSEAKPKKA--KVLEKKSIEEEKLEDKKEKQTESAIDEKSQK----AEVS 5016
Query: 7898 EDIGTYVKVQVPDDEIKGDGHDSVAAQKEETSSIEEKREVEHVKAEMEDAIKHEVSVEEK 8077
E + + + + K + DS A K+ ++ E+E + + E + +V+ + K
Sbjct: 5017 ETVSEKITDEKAQESQKKEVKDSEAKPKKAKILEKKSIEIEKLDEKKEKQTETKVATDTK 5076
Query: 8078 NNTSENIDHEAAKEIEQEEGKQTNIVXXXXXXXXXXXNQ--ESFNNVKETDDAIDKTQPE 8251
+ T E + ++I +E+ +++ V + E + +KE D DK Q E
Sbjct: 5077 SQTVE-VSEIVLEKISEEKAEESQKVELKDSEAKSKKAKVLEKKSTLKEKLDENDKKQKE 5135
Query: 8252 IRDIESLSSVSKTQDKPEPEYEVPNQQKREITNEVPSLE 8368
+ K E VP + E E+ + E
Sbjct: 5136 -------DGATNKSQKAEAADVVPEKISEEKVAEIKTPE 5167
Score = 181 bits (460), Expect = 1e-43
Identities = 437/2421 (18%), Positives = 904/2421 (37%), Gaps = 170/2421 (7%)
Frame = +2
Query: 1751 VHESESLKENAEPVEAVKNSDGTEQISREVTVDRAKEEDIAPKTEEIQERPSESKASLEP 1930
V E E L+E+ + E D T++ S EV +A E+I E + E+ S+S +
Sbjct: 2307 VSEQEKLQESKQQTEV----DDTQK-STEVVSQKASPENIL---EALSEKLSQSPNNATQ 2358
Query: 1931 KEEVDHISNETEEHEHVLERDVQQCETIESEAVETKEDTQPSLDLKEDKETEEAETFKTV 2110
+E+ I E ++ +L+ ++ E + + +E + D K +E E E + +
Sbjct: 2359 NDEIKTIMTECQD---ILD-NIDNIEKVSKSIFKLREHIVHTFDGKPPEEQTEKELVEKL 2414
Query: 2111 FSSDEVRSSAVQEEQFGEHTEPCSSEIKDESHGKEESVEVKSQETVQDENTEDKHDVLKV 2290
S E + + EIK + ++++ + D N K +L V
Sbjct: 2415 IESLFESCPEATEHVIQTYIK----EIKTNIILTKAAIQL-----IDDSNLFTKPSLL-V 2464
Query: 2291 PSTESEKYQGNEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELNDE---KIN--VDQVDG 2455
P + + +TV + + S E + + + + ++L DE KIN ++ +
Sbjct: 2465 PKLVNLEKLSELTQTVKLIDKSSKEMIGLQQNLMDIFIILDDLLDERTEKINPKIENIKK 2524
Query: 2456 TQIMEEPIGLDSNGAEAEQIDQNITNETEEILVAKPVSLLD-VKSVEQMQKPKLESPSEV 2632
+ E D + Q++ + N +++ K + + + K + + Q ++ ++
Sbjct: 2525 ILLSE----YDYIEKKEGQLNTAVVNGKIKLITEKILDICEEFKQIIESQNQNKDAAGDI 2580
Query: 2633 SEETSKTVDXXXXXXXXXXVTLYQEGQVDGSYGLETKEETVSVXXXXXXXXXXXXXRSVI 2812
+ ++ V ++ +D + LE KE S
Sbjct: 2581 KKSETEDVVDHSIEKKIEEPKRSEKKDLDKEF-LEEKELKASAKKQGDQDIEQKS----- 2634
Query: 2813 DPTPLQKPTXXXXXXXXXXXXKTVDEKIEEKTDSIELGEIAQEERSVTDLTPLQE---ES 2983
QKP K + K E+ D+ E E+ +V D L+E E+
Sbjct: 2635 -----QKPEVSEVVAEKISEGKIEEPKKPEEMDT----EAKSEKATVLDKQVLEEKELEA 2685
Query: 2984 SQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSASPSKELEGETVVXXXXXXXXXXXXXXX 3163
S + +++ + + +P EV ++++ E P K +T +
Sbjct: 2686 SAEKQGDQDVEKKSQKPEVSEVVAEKISEETIEEPKKPEVKDTEIKSEKATALDKQVLEE 2745
Query: 3164 XXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVAEEIVDEKAKEEVPMLQIKNED----D 3331
+ Q V ++E+ ++E K EV +IK+E D
Sbjct: 2746 KELEASAQKQCDQDVEKKSQKPEVSEIVAE-KISEKTIEEPKKPEVKDTEIKSEKATALD 2804
Query: 3332 ATKIHETRVE-----------QARDIGPSLTEICSINQNQPEEQVKEACSKEEQEKEIST 3478
+ E +E + + P ++E+ + + EE ++E E +E E+ +
Sbjct: 2805 KQVLEEKELEASAQKQGDQDVEKKSQKPEVSEV--VAEKISEETIEEPKKPEVKETEVKS 2862
Query: 3479 NSENIVNETYALHSVXXXXXXXXXNGESLDDVETTKSXXXXXXXXXXXXXXXXXXXPRLD 3658
++++ + + DVE P+
Sbjct: 2863 EKATVLDKQV----LEEKELEASAQKQGDQDVEKKFQKAEVSEVVAEKISEETIEEPKKP 2918
Query: 3659 AIXXXXXXXXXXXXQDAKIVNNEETTAHESESLKGDNHQEKNAEPVEATQNLDDAEQISR 3838
+ D +++ +E A S +GD EK ++ E ++ + AE+IS
Sbjct: 2919 EVKDTEIKSEKATALDKQVLEEKELEA--SAQKQGDQDVEKKSQKPEVSEVI--AEKISE 2974
Query: 3839 EVTVDTEREADITEKIEKVQEGPTVIETPTIQGEDIESETSLELKEEVDQSSKDTEEHEH 4018
E + ++ + ++ E E TV++ ++ +++E+ + ++V++ S+ E E
Sbjct: 2975 EKIEEPKKPEE--KETEVKSEKATVLDKQVLEEKELEASAQKQGDQDVEKRSQKPEVSEV 3032
Query: 4019 VLER--DIPQCETLKAEAVDTSTVEEAAILKTLETNISEPEAMHSETSLDLKVDKEQKEA 4192
V E+ + E K E +T E A TL+ + E + + D E+K
Sbjct: 3033 VAEKVSEGKIEEPKKPEVKETEAKSEKAT--TLDMQVLEERELEASAQKQGDQDVEKKSQ 3090
Query: 4193 ETVKTVIFSNEVGTSDAQAEEFGEHTEPCSSEIKDESQGXXXXXXXXXXXTVQGESSEEK 4372
+ + + + ++ + + E E +E+K E + + EEK
Sbjct: 3091 KPEVSEVIAEKISEEKIEEPKKPEEKE---TEVKSEK-----------ATVLDKQVLEEK 3136
Query: 4373 DVNMLDVQSGESEKYQENE-PDIS-LVSKTENGDKFEEIPSVVEGAGLDETTHNQTLLDV 4546
++ + G+ + ++++ P++S +V++ + K EE P E + + T LD
Sbjct: 3137 ELEASAQKQGDQDVEKKSQKPEVSEVVAEKVSEGKIEE-PKKPEVKETEVKSEKATTLDK 3195
Query: 4547 ESVVKQSLDTPSEEETSXXXXXXXXXXXXXXVTLHQEGREEGSYGLDTKDEAVSVLESRE 4726
+ + ++ L+ ++++ L + + GS + DE + ESRE
Sbjct: 3196 QVLEEKELEASAQKQGDQDGKSRDDIIKTLKERLTELSKALGS----SVDEILR--ESRE 3249
Query: 4727 LGEQPQQEELCLAN-----------------EQENETKLQEEQVDKH-EPTKEEVSNDQQ 4852
+ + +++ + E+ E +L E ++ E + E +
Sbjct: 3250 IVNNLEDDKVVAKHLFKLRDHIVHTYDGKRGEENKEKELFESFIELLCEASPEAAEKVKL 3309
Query: 4853 SPVEEI-SNEVIQVSSASLSEGPEYET---VVEAEKIGEEQVADKIQKSFETGEIVEAHS 5020
+ ++EI +N ++ ++ L + T ++ + + E+VA KIQ + E
Sbjct: 3310 NYLKEIKTNVILTKATIQLIDDSNMFTKPSLLIPKLLNLERVAVKIQSETYVDKSSEKMI 3369
Query: 5021 SLPSSSEE----------KEHETVSEKTDDEKV-----------KDAE--------PIGD 5113
SL S + E E + K ++ K KD I
Sbjct: 3370 SLQQSLMDIFVILDDFLDDETEVLKPKIENIKTTLLSDYDYIEKKDGPLLTAVINGKINV 3429
Query: 5114 MRERGLDIAETTHLSLPSVDQKE-DVDEIHIPSVALPLDEQEKVTSTEKGETKSSEAE-- 5284
+ + L I E + DQKE DV + A EK ++K E K SEA+
Sbjct: 3430 VSQHILTIIEEVKQLTENHDQKEKDVSNAEADNFA-----DEKREESQKEEIKDSEAKHK 3484
Query: 5285 ---------------DDKPDEHVDSS---------TSPMLSEK-NDNETQTSKTSE--DV 5383
+DK ++ +S+ S ++SEK D + Q S+ E
Sbjct: 3485 KSKVSEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGS 3544
Query: 5384 CMQQEESGTLEVPKPEESK-EDKSQXXXXXXXXXXXXXDQTLPIETSHTDNTLSSELVSE 5560
+ +++ LE EE K EDK + + I + + + E +
Sbjct: 3545 EAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKK 3604
Query: 5561 QDDQSPXXXXXXXXXXXXXAHDVEATSERNLPVET--------SDADNTLSSQLVSETKE 5716
+ S + + ++ ++ ++ T+S ++ E +
Sbjct: 3605 EVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSETVSEKITDEKAQ 3664
Query: 5717 EHKLQAGEILPTEIIPRESSDEALVSMLASREDDKVALQEDNCADDVRETNDIQEERSIS 5896
E Q E+ +E P+++ S+ + +DK Q ++ D+ + ++ E
Sbjct: 3665 ES--QKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSE----- 3717
Query: 5897 VETEESVGETKPKEHEDEIRDAHVETPTAPIILEENDSETLIAEAKKGNEEINETERTVA 6076
+ +E+ E + + E++D+ + A ++ +++ E + + K ET+ A
Sbjct: 3718 IVSEKITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKK-------ETQTDSA 3770
Query: 6077 LDHEEEFVNHEAPKLEETKDEKSQEI-----------PETAKATETTIDQTLPIGTSQAD 6223
+D + + E+ DEK+QE P+ AK E + + +
Sbjct: 3771 IDEKSQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEK 3830
Query: 6224 QTPSLVSDKDDQTPKQVXXXXXXXXXXTHKVQAEDIFSTETVPKESFIEAPVSMLASGED 6403
QT S + +K + + Q +++ +E PK++ + S+ +
Sbjct: 3831 QTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEEEKLE 3890
Query: 6404 EPVTPQEGDYAANTQEERHVSAETEEKVGETKPKESQAEGAEKSDDQVEDESTK---KTD 6574
+ Q ++ VS EK+ + K +ESQ E E D + + + K K
Sbjct: 3891 DKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQME--EVKDSEAKPKKAKVLEKKS 3948
Query: 6575 VEVAGLENDYPTEEAEHGDETYSTLPVVGIXXXXXXXXXXXRAINDSASSEVSMIKEPAD 6754
+E LEN + DE +++ S +++ E A
Sbjct: 3949 IEEEKLENKKEKQTESAIDE-----------------KSQKAEVSEIVSEKIT--DEKAQ 3989
Query: 6755 QEEKKGDDVVESNEKDFVSDILEAKRLHGDKSGEAEKIKEESGLAGKSLPIEEINLXXXX 6934
+ +KK +V +S K + +LE K + +K + ++ + ES + KS E +
Sbjct: 3990 ESQKK--EVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEI---- 4043
Query: 6935 XXXXXXXXXTREIAQVLPREEILIS-SSPLSAE--EQEHVISDEKQEEREPQQDF----- 7090
T E AQ ++E+ S + P A+ E++ + ++ ++++E Q D
Sbjct: 4044 ----VSENITDEKAQESQKKEVKDSEAKPKKAKVLEKKSIEEEKLEDKKETQTDSAIDEK 4099
Query: 7091 --NGSTSEKISLQVEHLKDFETSKKEQKDETHETVXXXXXXXXXXXXXXXXXXXXXXSSE 7264
SE +S ++ K E+ K+E KD + E
Sbjct: 4100 SQKAEVSEIVSEKITDEKAQESQKEEVKDSEAKP-------------KKAKVLEKKSIEE 4146
Query: 7265 VKKDNKDARELEVGNDFVSRDGEKEEVPHNALENEEEMNEVVASEKQISDPVGVIKKASE 7444
K ++K ++ E D S+ E E+ + +E+ + +K++ D KKA
Sbjct: 4147 EKLEDKKEKQTESAIDEKSQKAEVSEIVSENITDEKAQE---SQKKEVKDSEAKPKKAKV 4203
Query: 7445 AEHEDPVDDIKSNDDRDFPTEQAPKDQSDEVSADETVPKEAIGEELKVPSSKVLDD---- 7612
E + +++ K D ++ TE A ++S + E V ++ E+ + K + D
Sbjct: 4204 LEKKS-IEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITEEKAQESQKKEVKDSKAK 4262
Query: 7613 ------IQENSNTEAVTNFADRDLPVQNLSELIQSHQSPNQVEETSFEFNKAQEDKKEET 7774
+++ S EA + E Q + V E + KAQE +KEE
Sbjct: 4263 PKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITD-EKAQESQKEEV 4321
Query: 7775 VDALITNVQVQDQPKEDFEAAAIEKEISEQEHKLNDLTDVQEDIGTYVKVQVPDDEIKGD 7954
D+ + + K+ E +E + +Q D + ++ V ++ D++ +
Sbjct: 4322 KDSEAKPKKAKVLEKKSIEEEKLENKKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQES 4381
Query: 7955 GHDSV--AAQKEETSSIEEKREVEHVKAEMEDAIKHEVSVEEKNN-------TSENIDHE 8107
V + K + + + EK+ +E K E + + E +++EK+ SE I E
Sbjct: 4382 QKKEVKGSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITDE 4441
Query: 8108 AAKEIEQEEGKQTNIVXXXXXXXXXXXNQESFNNVK---ETDDAIDK--TQPEIRDI--E 8266
A+E ++EE K + +E+ K +TD AID+ + E+ +I E
Sbjct: 4442 KAQESQKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSE 4501
Query: 8267 SLSSVSKTQDKPEPEYEVPNQQKREITNEVPSLENSXXXXXXXXXXXXXXNTKDLFSVVK 8446
++ + + E + + K+ E S+E + + K + V
Sbjct: 4502 KITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVS 4561
Query: 8447 E--TEPTLKEPARKSLSDHIQ 8503
E +E E A++S + ++
Sbjct: 4562 EIVSEKITDEKAQESQKEEVK 4582
Score = 130 bits (327), Expect = 4e-28
Identities = 234/1153 (20%), Positives = 463/1153 (39%), Gaps = 61/1153 (5%)
Frame = +2
Query: 236 KKPKN*NAKMEKRQRLSRF*MTVRSLKMIKNLLSFREPQSLNEKKEDEKIILSDVT---- 403
K+ K+ AK +K + L + + L+ K + ++K E +I+ +T
Sbjct: 4059 KEVKDSEAKPKKAKVLEKKSIEEEKLEDKKETQTDSAIDEKSQKAEVSEIVSEKITDEKA 4118
Query: 404 LENKKEE--DTTGKPEEVSV-EKPVIEEDQTEAKHSLEQEEDIGNISKVLTDTTPVKVDE 574
E++KEE D+ KP++ V EK IEE++ E K + E I S+ + + + +
Sbjct: 4119 QESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQK-AEVSEIVSEN 4177
Query: 575 YDIEKSLNSVCEEIPIKTDEVREET----DSRTVETSVNGTEAEHNATVSVEEISRNGDN 742
EK+ S +E+ K E + + + +++E + E +++E S+ +
Sbjct: 4178 ITDEKAQESQKKEV--KDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAE- 4234
Query: 743 TVNETVSEDQTATDGEPLHDVETIKREAEPFYKTVVEDAKIVNTEETTAHESKILKEDNH 922
V+E VSE T + E +A+P V+E I EE + K + D+
Sbjct: 4235 -VSEIVSEKITEEKAQESQKKEVKDSKAKPKKAKVLEKKSI---EEAKLEDKKETQTDSA 4290
Query: 923 QEEYAESVEATKNSDAAEQSSREVTVDKEKEEDIIQNIEEVQESPSVMESPTIQGEDIES 1102
+E ++ E ++ +E+ + E + +KEE +++ E + V+E +I+ E +E+
Sbjct: 4291 IDEKSQKAEVSEI--VSEKITDEKAQESQKEE--VKDSEAKPKKAKVLEKKSIEEEKLEN 4346
Query: 1103 KASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVTEAKTAETFSVQEAEILKTNINE 1282
K E +D+ ++ E E V + E+ E K +E + + K +I E
Sbjct: 4347 KKEKQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKGSEAKPKKAKVLEKKSIEE 4406
Query: 1283 SEAHSAIGGEEDGQETKENTEPSKDLKDDKEQEDSETVKTIISSDEVRSSDVQAEVFGEH 1462
+ ED +E + TE + D K K E SE V I+ ++ + S + EV
Sbjct: 4407 EKL-------EDKKE--KQTESAIDEKSQKA-EVSEIVSEKITDEKAQESQKE-EVKDSE 4455
Query: 1463 TEPCSSEIKDDRHGRDESIEVKAKETGPEIETAVDGESVHEIETTERVLLEAXXXXXXXX 1642
+P +++ + + + +E K KET + ++A+D +S + E +E V +
Sbjct: 4456 AKPKKAKVLEKKSIEEAKLEDK-KET--QTDSAIDEKS-QKAEVSEIVSEKITDEKAQES 4511
Query: 1643 XXXXXXPSLNAIEKAETXXXXXXXXXXXXXXXXXTSVHESESLKENAEPVEAVKNSDGTE 1822
S +KA+ + + + AE E V T+
Sbjct: 4512 QKEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEVSEIVSEKI-TD 4570
Query: 1823 QISREVTVDRAKEEDIAPKTEEIQERPSESKASLEPKEE------VDHISNETEEHEHVL 1984
+ ++E + K+ + PK ++ E+ S + LE K+E +D S + E E V
Sbjct: 4571 EKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVS 4630
Query: 1985 ER------------------------DVQQCETIESEAVETKEDTQPSLDLKEDKETEEA 2092
E+ V + ++IE +E K++TQ + E + E
Sbjct: 4631 EKITDEKAQESQMEEVKDSEAKPKKAKVLEKKSIEEAKLEDKKETQTDSAIDEKSQKAEV 4690
Query: 2093 ETFKTVFSSDEVRSSAVQEEQFGEHTEPCSSEIKDESHGKEESVEVKSQ---ETVQDENT 2263
+ +DE + +EE +P +++ ++ +EE +E K + E+ DE +
Sbjct: 4691 SEIVSEKITDEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKS 4750
Query: 2264 EDKHDVLKVPSTE--SEKYQGNEPETVLVSNTGSYEKSEKSPSDLVLNVDKEELNDEKIN 2437
+ K +V ++ S + EK Q ++ + V GS K +K+ ++++E+L D+K
Sbjct: 4751 Q-KAEVSEIVSEKITDEKAQESQKKEV----KGSEAKPKKAKVLEKKSIEEEKLEDKKEK 4805
Query: 2438 -----VDQVDGTQIMEEPIGLDSNGAEAEQIDQNITNETEEILVAKP--VSLLDVKSVEQ 2596
+D+ + E + +A++ + ++E AKP +L+ KS+E+
Sbjct: 4806 QTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSE----AKPKKAKVLEKKSIEE 4861
Query: 2597 MQKPKLESPSEVSEETSKTVDXXXXXXXXXXVTLYQ--EGQVDGSYGLETKEETVSVXXX 2770
KLE+ E ++T +D + + + + S E K+
Sbjct: 4862 ---EKLENKKE--KQTESAIDEKSQKAEVSEIVSEKITDEKAQESQKKEVKDSEAKPKKA 4916
Query: 2771 XXXXXXXXXXRSVIDPTPLQKPTXXXXXXXXXXXXKTVDEKI-EEKTDSIELGEIAQEER 2947
+ D Q + +TV EKI +EK + E+ E
Sbjct: 4917 KVLEKKSIEEEKLEDKKEKQTESAIDEKFQKAEVSETVSEKITDEKAEESRKEEVKDSEA 4976
Query: 2948 SVTDLTPLQ----EESSQPNEQEKETKLEKHEPTNEEVKSDEVIEVLSASPSKELEGETV 3115
L+ EE +++EK+T+ E + + S+ V E ++ ++E + + V
Sbjct: 4977 KPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSETVSEKITDEKAQESQKKEV 5036
Query: 3116 VXXXXX-XXXXXXXXXXXXXXXXXSLETVQTVXXXXXXXXXXXXQDHVTVAEEIVDEKAK 3292
+ QT + V E+I +EKA
Sbjct: 5037 KDSEAKPKKAKILEKKSIEIEKLDEKKEKQTETKVATDTKSQTVEVSEIVLEKISEEKA- 5095
Query: 3293 EEVPMLQIKNEDDATKIHETRVEQARDIGPSLTEICSINQNQPEEQVKEACSKEEQEKEI 3472
EE +++K+ E + ++A+ + T +++N +++ A +K ++ +
Sbjct: 5096 EESQKVELKDS-------EAKSKKAKVLEKKSTLKEKLDENDKKQKEDGATNKSQKAEAA 5148
Query: 3473 STNSENIVNETYA 3511
E I E A
Sbjct: 5149 DVVPEKISEEKVA 5161
Score = 37.7 bits (86), Expect = 3.3
Identities = 71/312 (22%), Positives = 123/312 (38%), Gaps = 6/312 (1%)
Frame = +2
Query: 4496 EGAGLDETTHNQTLLDVESVVKQSLDTPSEEETSXXXXXXXXXXXXXXVTLHQEGREEGS 4675
E A + ++ L + E SL T EE TS +T+ ++G + S
Sbjct: 678 EDAQRSQQQKSEQLHENELQRNYSLSTIQEERTSQLYETPVGD-----ITIDEKG--DVS 730
Query: 4676 YGLDTKDEAVSVLESRELGEQPQQEELCLANEQENETKLQEEQVDKHEPTKEEVSNDQQS 4855
+ D K+ +VS+ E+ +L E+ + + + +Q +E + V+ P V QS
Sbjct: 731 FSFDGKEVSVSLYETPDLTEEEALKIVEMYADQISEHVTEHNIVEL--PPLRFVKETSQS 788
Query: 4856 PVEEISNEVIQVSSASLSEGPEYETVVEAEKIGEEQVADKIQKSFETGEIVEAHSSLPSS 5035
+ VI +S PEY TV E + E + D EI SS
Sbjct: 789 GKLLMEAVVIDIS-------PEYFTV-EDDMRTEADMDD-----ISINEITVHGSSGREG 835
Query: 5036 SEEKEHETVSEKTDDEKVKDAEPIGDMRERG----LDIAETTHLSLPSVDQ-KEDVDEIH 5200
++E E +++ D+ ++ +R+R + E LS S Q E+ E+
Sbjct: 836 RVDRETEQYVQQSFDKMEEELSLSAPIRKRKKSKPTETDEFFSLSKASGSQGDEETSEL- 894
Query: 5201 IPSVALPLDEQEKVTSTEKGETKSSEAEDDKPDEHVDSSTSPMLSE-KNDNETQTSKTSE 5377
Q ++ K++ P++ DS P + K +T +SKT+E
Sbjct: 895 ----------QTFASAQMSASQKAASGAQASPEKDKDSVAPPKRKKSKKPTDTDSSKTTE 944
Query: 5378 DVCMQQEESGTL 5413
D Q+ SG +
Sbjct: 945 DDARLQDISGAV 956
Score = 36.6 bits (83), Expect = 7.3
Identities = 35/132 (26%), Positives = 65/132 (48%), Gaps = 1/132 (0%)
Frame = +2
Query: 863 IVNTEETTAHESKILKEDNHQEEYAESVEATKNSDAAEQSSREVTVDKEKEEDIIQNIEE 1042
+++ EE HE KIL+++ Q+E +A++ D + + R+V K E+ + NIE
Sbjct: 1477 VIDIEE---HEFKILQQEIQQDE----EQASQQQDKSFSALRKVLETKVSLEEAVGNIET 1529
Query: 1043 VQES-PSVMESPTIQGEDIESKASLDHEEEMDKITKDTEEQEHVLVRDVPVPQSETLVTE 1219
+QE+ + E+P KAS +++ + E + L+R + + + +E
Sbjct: 1530 LQEALNKISENP---------KAS-------ERVKSSSNEAQVYLLRILQIAKGLATFSE 1573
Query: 1220 AKTAETFSVQEA 1255
A+T T V EA
Sbjct: 1574 AET--TLDVNEA 1583
Database: BlastDB/NCBI/blast/db/2003_02_17_02_00_1/nr
Posted date: Feb 17, 2003 10:02 AM
Number of letters in database: 429,188,541
Number of sequences in database: 1,339,046
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
length of database: 429,188,541
effective HSP length: 141
effective length of database: 240,383,055
effective search space used: 678841747320
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)