BLASTX 1.4.13-Paracel [2002-12-12]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PTA.sd.15001.C1
(14,221 letters)
Database: BlastDB/NCBI/blast/db/2003_02_17_02_00_1/nr
1,339,046 sequences; 429,188,541 total letters
Searching...................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_197702.1| putative protein; protein id: At5g23110.1 ... 8986 0.0
gb|AAM97006.1| putative protein [Arabidopsis thaliana]|gi|2... 1170 0.0
ref|NP_055178.1| spastic ataxia of Charlevoix-Saguenay (sac... 266 7e-69
ref|XP_224256.1| similar to sacsin [Mus musculus] [Rattus n... 258 2e-66
ref|NP_056603.1| sacsin [Mus musculus]|gi|13124519|sp|Q9JLC... 256 6e-66
>ref|NP_197702.1| putative protein; protein id: At5g23110.1 [Arabidopsis
thaliana]|gi|9759369|dbj|BAB09828.1|
gene_id:MYJ24.10~ref|NP_055178.1~similar to unknown
protein [Arabidopsis thaliana]
Length = 4706
Score = 8986 bits (23318), Expect = 0.0
Identities = 4509/4706 (95%), Positives = 4509/4706 (95%)
Frame = +1
Query: 1 MDSLLLEDFGQKVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLDRRVHGSG 180
MDSLLLEDFGQKVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLDRRVHGSG
Sbjct: 1 MDSLLLEDFGQKVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLDRRVHGSG 60
Query: 181 SLLSDSLAQWQGPSLLAYNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHLT 360
SLLSDSLAQWQGPSLLAYNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHLT
Sbjct: 61 SLLSDSLAQWQGPSLLAYNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHLT 120
Query: 361 DIPSFVSGKYVVLFDPQGAYLPNISAANPGKRIDYVGSSALSQYKDQFLPYCAFGCDMRS 540
DIPSFVSGKYVVLFDPQGAYLPNISAANPGKRIDYVGSSALSQYKDQFLPYCAFGCDMRS
Sbjct: 121 DIPSFVSGKYVVLFDPQGAYLPNISAANPGKRIDYVGSSALSQYKDQFLPYCAFGCDMRS 180
Query: 541 PFNGTLFRFPLRNTEQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLFLKCVLSIEMYT 720
PFNGTLFRFPLRNTEQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLFLKCVLSIEMYT
Sbjct: 181 PFNGTLFRFPLRNTEQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLFLKCVLSIEMYT 240
Query: 721 WDDGDSEPKKLYSCSVSSPNNDTVWHRQAVLRLSKTSISGDREMDAFTLEFLSESEKGNQ 900
WDDGDSEPKKLYSCSVSSPNNDTVWHRQAVLRLSKTSISGDREMDAFTLEFLSESEKGNQ
Sbjct: 241 WDDGDSEPKKLYSCSVSSPNNDTVWHRQAVLRLSKTSISGDREMDAFTLEFLSESEKGNQ 300
Query: 901 TKRRTDRFYIVQTMASASSKIGLFAATASKEYDIHLLPWASVAACISDDSSENNILKLGH 1080
TKRRTDRFYIVQTMASASSKIGLFAATASKEYDIHLLPWASVAACISDDSSENNILKLGH
Sbjct: 301 TKRRTDRFYIVQTMASASSKIGLFAATASKEYDIHLLPWASVAACISDDSSENNILKLGH 360
Query: 1081 AFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKVRSAWNRLLLEDVVAPSFA 1260
AFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKVRSAWNRLLLEDVVAPSFA
Sbjct: 361 AFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKVRSAWNRLLLEDVVAPSFA 420
Query: 1261 RLLLCLREVLDSRDSYFSLWPSGSFEAPWSILVEQIYKNICNAPVLFSDLDGGKWVSPAD 1440
RLLLCLREVLDSRDSYFSLWPSGSFEAPWSILVEQIYKNICNAPVLFSDLDGGKWVSPAD
Sbjct: 421 RLLLCLREVLDSRDSYFSLWPSGSFEAPWSILVEQIYKNICNAPVLFSDLDGGKWVSPAD 480
Query: 1441 AYLHDEEFSGSKDLGDALLQLEMPIVCLPRLVFDMLLKHPSFLLPKVVTPDRVRNFLKEC 1620
AYLHDEEFSGSKDLGDALLQLEMPIVCLPRLVFDMLLKHPSFLLPKVVTPDRVRNFLKEC
Sbjct: 481 AYLHDEEFSGSKDLGDALLQLEMPIVCLPRLVFDMLLKHPSFLLPKVVTPDRVRNFLKEC 540
Query: 1621 XXXXXXXXXXXXXXXEYCLDDLTDDSVCTQASNLKLLPLANGDFGFFSGRTGSVSYFICD 1800
EYCLDDLTDDSVCTQASNLKLLPLANGDFGFFSGRTGSVSYFICD
Sbjct: 541 KTLSALKKSLKLVLLEYCLDDLTDDSVCTQASNLKLLPLANGDFGFFSGRTGSVSYFICD 600
Query: 1801 ELEHMLLQKVYDRVIDKNIPPPLYTRLFAIAESRTANVAIFSIHNLLQLFPRLVPAEWKH 1980
ELEHMLLQKVYDRVIDKNIPPPLYTRLFAIAESRTANVAIFSIHNLLQLFPRLVPAEWKH
Sbjct: 601 ELEHMLLQKVYDRVIDKNIPPPLYTRLFAIAESRTANVAIFSIHNLLQLFPRLVPAEWKH 660
Query: 1981 RSKISWHPESNRDHPSSSWFVLFWQYLDKRCQSLSLFCDWPILPSTSGYLYIASPQSKLI 2160
RSKISWHPESNRDHPSSSWFVLFWQYLDKRCQSLSLFCDWPILPSTSGYLYIASPQSKLI
Sbjct: 661 RSKISWHPESNRDHPSSSWFVLFWQYLDKRCQSLSLFCDWPILPSTSGYLYIASPQSKLI 720
Query: 2161 NAEKLPAAVRNVLEKIGGKILNNNIKVEHSDLSSFVSDASYTGVLESIFDAASSDLDGVQ 2340
NAEKLPAAVRNVLEKIGGKILNNNIKVEHSDLSSFVSDASYTGVLESIFDAASSDLDGVQ
Sbjct: 721 NAEKLPAAVRNVLEKIGGKILNNNIKVEHSDLSSFVSDASYTGVLESIFDAASSDLDGVQ 780
Query: 2341 NLIYDLNAQEKDELRSFLLDPKWHIGHQIGDLYLRICKILPIHRIYGETSAQESKYSDLV 2520
NLIYDLNAQEKDELRSFLLDPKWHIGHQIGDLYLRICKILPIHRIYGETSAQESKYSDLV
Sbjct: 781 NLIYDLNAQEKDELRSFLLDPKWHIGHQIGDLYLRICKILPIHRIYGETSAQESKYSDLV 840
Query: 2521 NPPKHLPPLDVPACLLGCEFILCCQGSEEDVLSRYYGIERMRKSNFYRQNVFNRIEVLQP 2700
NPPKHLPPLDVPACLLGCEFILCCQGSEEDVLSRYYGIERMRKSNFYRQNVFNRIEVLQP
Sbjct: 841 NPPKHLPPLDVPACLLGCEFILCCQGSEEDVLSRYYGIERMRKSNFYRQNVFNRIEVLQP 900
Query: 2701 EIRDQVMISILQDLPXXXXXXXXXXXXXXXXXFVPTVNGPLKRPSVLHDPRNEELYALLE 2880
EIRDQVMISILQDLP FVPTVNGPLKRPSVLHDPRNEELYALLE
Sbjct: 901 EIRDQVMISILQDLPQLCLEDRLLREELQNLEFVPTVNGPLKRPSVLHDPRNEELYALLE 960
Query: 2881 DSDCFPASGFQGSAILDMLQGLGLKTTVSPETILESARLVERLMHKDLEKAHSRGKVLFS 3060
DSDCFPASGFQGSAILDMLQGLGLKTTVSPETILESARLVERLMHKDLEKAHSRGKVLFS
Sbjct: 961 DSDCFPASGFQGSAILDMLQGLGLKTTVSPETILESARLVERLMHKDLEKAHSRGKVLFS 1020
Query: 3061 FLEVNAVKWLPDQSSEDDGAINRIFSRAATAFRPRNLTCNLVKFWSELKMICWCPVLVSA 3240
FLEVNAVKWLPDQSSEDDGAINRIFSRAATAFRPRNLTCNLVKFWSELKMICWCPVLVSA
Sbjct: 1021 FLEVNAVKWLPDQSSEDDGAINRIFSRAATAFRPRNLTCNLVKFWSELKMICWCPVLVSA 1080
Query: 3241 PFQTLPWPVVTSTVAPPKLVRPKTDMWLVSASMRILDGECSSTALAYNLGWLSHPGGSAI 3420
PFQTLPWPVVTSTVAPPKLVRPKTDMWLVSASMRILDGECSSTALAYNLGWLSHPGGSAI
Sbjct: 1081 PFQTLPWPVVTSTVAPPKLVRPKTDMWLVSASMRILDGECSSTALAYNLGWLSHPGGSAI 1140
Query: 3421 AAQLLELGKNNEILIDQVLRQELALAMPKIYSILARLLGSDEMDIVKAVLEGSRWIWVGD 3600
AAQLLELGKNNEILIDQVLRQELALAMPKIYSILARLLGSDEMDIVKAVLEGSRWIWVGD
Sbjct: 1141 AAQLLELGKNNEILIDQVLRQELALAMPKIYSILARLLGSDEMDIVKAVLEGSRWIWVGD 1200
Query: 3601 GFATLSEVVLDGPLQLVPYIRVIPTDLAVFRGLFVELGVREFLTPSDYADVLCRIAVRKG 3780
GFATLSEVVLDGPLQLVPYIRVIPTDLAVFRGLFVELGVREFLTPSDYADVLCRIAVRKG
Sbjct: 1201 GFATLSEVVLDGPLQLVPYIRVIPTDLAVFRGLFVELGVREFLTPSDYADVLCRIAVRKG 1260
Query: 3781 TSPLDPQEIRAAVLIAQQLAEAQFLDKVTIYLPDVSGRLFPSSDLVYNDAPWLTASDNLN 3960
TSPLDPQEIRAAVLIAQQLAEAQFLDKVTIYLPDVSGRLFPSSDLVYNDAPWLTASDNLN
Sbjct: 1261 TSPLDPQEIRAAVLIAQQLAEAQFLDKVTIYLPDVSGRLFPSSDLVYNDAPWLTASDNLN 1320
Query: 3961 SSFSAESTMLLNAKRTMQKFVHGNISNEVAEKLGVRSLRRVLLAESADSMNFSLSGAAEA 4140
SSFSAESTMLLNAKRTMQKFVHGNISNEVAEKLGVRSLRRVLLAESADSMNFSLSGAAEA
Sbjct: 1321 SSFSAESTMLLNAKRTMQKFVHGNISNEVAEKLGVRSLRRVLLAESADSMNFSLSGAAEA 1380
Query: 4141 FGQHEALTTRLKHILEMYADGPGILFELVQNAEDAGASEVTFLLDKTHYGTSSLLSPEMA 4320
FGQHEALTTRLKHILEMYADGPGILFELVQNAEDAGASEVTFLLDKTHYGTSSLLSPEMA
Sbjct: 1381 FGQHEALTTRLKHILEMYADGPGILFELVQNAEDAGASEVTFLLDKTHYGTSSLLSPEMA 1440
Query: 4321 DWQGPALYCFNNSVFTQQDMYAISRIGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFVSG 4500
DWQGPALYCFNNSVFTQQDMYAISRIGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFVSG
Sbjct: 1441 DWQGPALYCFNNSVFTQQDMYAISRIGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFVSG 1500
Query: 4501 ENIVMFDPHANHLPGISPTHPGLRIKFAGRYILDQFPDQFAPFLHFGCDLEHTFPGTLFR 4680
ENIVMFDPHANHLPGISPTHPGLRIKFAGRYILDQFPDQFAPFLHFGCDLEHTFPGTLFR
Sbjct: 1501 ENIVMFDPHANHLPGISPTHPGLRIKFAGRYILDQFPDQFAPFLHFGCDLEHTFPGTLFR 1560
Query: 4681 FPLRNASVAPRSHIKKETYAPEDVLSLFTSFSGVVSEALIFLRNVKTVSIFTKEGAGHEM 4860
FPLRNASVAPRSHIKKETYAPEDVLSLFTSFSGVVSEALIFLRNVKTVSIFTKEGAGHEM
Sbjct: 1561 FPLRNASVAPRSHIKKETYAPEDVLSLFTSFSGVVSEALIFLRNVKTVSIFTKEGAGHEM 1620
Query: 4861 QLLHRVCKDHNVGQDTEPKPSSQVFSLLDENIFAGMNKDQLLKKLSNTVVKDLPYKCQKI 5040
QLLHRVCKDHNVGQDTEPKPSSQVFSLLDENIFAGMNKDQLLKKLSNTVVKDLPYKCQKI
Sbjct: 1621 QLLHRVCKDHNVGQDTEPKPSSQVFSLLDENIFAGMNKDQLLKKLSNTVVKDLPYKCQKI 1680
Query: 5041 VVTEQDSSGCILHGWITGECLNAGVSKKNLNLPEMSHKLIPWASVAVHINSVKNENVEDL 5220
VVTEQDSSGCILHGWITGECLNAGVSKKNLNLPEMSHKLIPWASVAVHINSVKNENVEDL
Sbjct: 1681 VVTEQDSSGCILHGWITGECLNAGVSKKNLNLPEMSHKLIPWASVAVHINSVKNENVEDL 1740
Query: 5221 AASISNIFGPSTISIQNRRNFGGRAFCFLPLPITTGLPAHINAYFELSSNRRDLWFGNDM 5400
AASISNIFGPSTISIQNRRNFGGRAFCFLPLPITTGLPAHINAYFELSSNRRDLWFGNDM
Sbjct: 1741 AASISNIFGPSTISIQNRRNFGGRAFCFLPLPITTGLPAHINAYFELSSNRRDLWFGNDM 1800
Query: 5401 AGDGKVRSDWNLYLIEEVVVPAYGHLLEKIASELGPCDLFFSVWPVTLGTEPWASLVRKL 5580
AGDGKVRSDWNLYLIEEVVVPAYGHLLEKIASELGPCDLFFSVWPVTLGTEPWASLVRKL
Sbjct: 1801 AGDGKVRSDWNLYLIEEVVVPAYGHLLEKIASELGPCDLFFSVWPVTLGTEPWASLVRKL 1860
Query: 5581 YSFIANNGLRVLYTKARGGQWISTKQAIYPDFSFPKADELVDVLADAGLPVINISKTVAE 5760
YSFIANNGLRVLYTKARGGQWISTKQAIYPDFSFPKADELVDVLADAGLPVINISKTVAE
Sbjct: 1861 YSFIANNGLRVLYTKARGGQWISTKQAIYPDFSFPKADELVDVLADAGLPVINISKTVAE 1920
Query: 5761 RFGEACSSXXXXXXXXXXXXXXXXXXXXXDRNGXXXXXXXXXXXXKVPFXXXXXXXXXXX 5940
RFGEACSS DRNG KVPF
Sbjct: 1921 RFGEACSSLHLMTPQLLRTLLTRRKREFRDRNGLALALEYCLLDLKVPFLADLLYGLPLL 1980
Query: 5941 XXXXXSFTTFNKNGTAERIFFAEEIGYELLKDSLPHQLVDREVPEGVYSKLLAVAQSGES 6120
SFTTFNKNGTAERIFFAEEIGYELLKDSLPHQLVDREVPEGVYSKLLAVAQSGES
Sbjct: 1981 PLADGSFTTFNKNGTAERIFFAEEIGYELLKDSLPHQLVDREVPEGVYSKLLAVAQSGES 2040
Query: 6121 CICLLSCNLLEKLFFKLLPADWHLSEKILWTPGQRGHPTVEWIRVLWSYLKLSCDDLSVF 6300
CICLLSCNLLEKLFFKLLPADWHLSEKILWTPGQRGHPTVEWIRVLWSYLKLSCDDLSVF
Sbjct: 2041 CICLLSCNLLEKLFFKLLPADWHLSEKILWTPGQRGHPTVEWIRVLWSYLKLSCDDLSVF 2100
Query: 6301 SKWPILPVEDGCLMQLILNSNVIRDDGWSENMSSLLLKCGCRFLNRELPVEHPQLETFVQ 6480
SKWPILPVEDGCLMQLILNSNVIRDDGWSENMSSLLLKCGCRFLNRELPVEHPQLETFVQ
Sbjct: 2101 SKWPILPVEDGCLMQLILNSNVIRDDGWSENMSSLLLKCGCRFLNRELPVEHPQLETFVQ 2160
Query: 6481 PPTATGILNALLAISGGHENIKGIFLNVSEGELHELRNFILQSKWFSGGHMNEVHFETIK 6660
PPTATGILNALLAISGGHENIKGIFLNVSEGELHELRNFILQSKWFSGGHMNEVHFETIK
Sbjct: 2161 PPTATGILNALLAISGGHENIKGIFLNVSEGELHELRNFILQSKWFSGGHMNEVHFETIK 2220
Query: 6661 HLPIFESYRSRKLVSLNCPVKWLKPDGIREDLLDDDFVRLDSERERTIFKRYLQIKEPSK 6840
HLPIFESYRSRKLVSLNCPVKWLKPDGIREDLLDDDFVRLDSERERTIFKRYLQIKEPSK
Sbjct: 2221 HLPIFESYRSRKLVSLNCPVKWLKPDGIREDLLDDDFVRLDSERERTIFKRYLQIKEPSK 2280
Query: 6841 MEFYKACVLNRMSEFLSQQEALLAILHDLNDLVVADVSLQCAISTTPFVLAANGLWQQPS 7020
MEFYKACVLNRMSEFLSQQEALLAILHDLNDLVVADVSLQCAISTTPFVLAANGLWQQPS
Sbjct: 2281 MEFYKACVLNRMSEFLSQQEALLAILHDLNDLVVADVSLQCAISTTPFVLAANGLWQQPS 2340
Query: 7021 RLYDPRVPALQELLHKEVYFPSEKFSDSKILDALVGLGLRTTLDCSTYLDAARSVSMLHD 7200
RLYDPRVPALQELLHKEVYFPSEKFSDSKILDALVGLGLRTTLDCSTYLDAARSVSMLHD
Sbjct: 2341 RLYDPRVPALQELLHKEVYFPSEKFSDSKILDALVGLGLRTTLDCSTYLDAARSVSMLHD 2400
Query: 7201 LGDLEASRYGRRLLFHIKTLSIKLSSKTGEANHDESQNIMSITSEDSFDGXXXXXXXXXX 7380
LGDLEASRYGRRLLFHIKTLSIKLSSKTGEANHDESQNIMSITSEDSFDG
Sbjct: 2401 LGDLEASRYGRRLLFHIKTLSIKLSSKTGEANHDESQNIMSITSEDSFDGETYPEYETET 2460
Query: 7381 XXLGSLLTQQSEDEFWCQLRSIPWCPICLDPPIEGIPWLESSNLVASPDRVRPKSQMFLV 7560
LGSLLTQQSEDEFWCQLRSIPWCPICLDPPIEGIPWLESSNLVASPDRVRPKSQMFLV
Sbjct: 2461 SYLGSLLTQQSEDEFWCQLRSIPWCPICLDPPIEGIPWLESSNLVASPDRVRPKSQMFLV 2520
Query: 7561 SATMHLLDGECQSSYLHQKLGWMDCLTIDILCRQLIEISKSYKEQKSRSSVNPEFESMLQ 7740
SATMHLLDGECQSSYLHQKLGWMDCLTIDILCRQLIEISKSYKEQKSRSSVNPEFESMLQ
Sbjct: 2521 SATMHLLDGECQSSYLHQKLGWMDCLTIDILCRQLIEISKSYKEQKSRSSVNPEFESMLQ 2580
Query: 7741 SQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDFVSADVLSFDSPVKFTPYLYVVP 7920
SQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDFVSADVLSFDSPVKFTPYLYVVP
Sbjct: 2581 SQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDFVSADVLSFDSPVKFTPYLYVVP 2640
Query: 7921 SELSDFKELLLELGVRLSFDAADYMNTLQHLQNDIKGSQLTDEQINFVLCVLEAVADCFX 8100
SELSDFKELLLELGVRLSFDAADYMNTLQHLQNDIKGSQLTDEQINFVLCVLEAVADCF
Sbjct: 2641 SELSDFKELLLELGVRLSFDAADYMNTLQHLQNDIKGSQLTDEQINFVLCVLEAVADCFS 2700
Query: 8101 XXXXXXXXXXXXXXXXAGFLVPLEDLVYNDAPWVDSSSLSGKRFVHPSINSDMANRLGIQ 8280
AGFLVPLEDLVYNDAPWVDSSSLSGKRFVHPSINSDMANRLGIQ
Sbjct: 2701 EVSSDSDNNSVLVPDSAGFLVPLEDLVYNDAPWVDSSSLSGKRFVHPSINSDMANRLGIQ 2760
Query: 8281 SLRCISLVDNDITQDLPCMDFTKLKELLSLYASKXXXXXXXXXXADCCKVKKLHIIFDKR 8460
SLRCISLVDNDITQDLPCMDFTKLKELLSLYASK ADCCKVKKLHIIFDKR
Sbjct: 2761 SLRCISLVDNDITQDLPCMDFTKLKELLSLYASKDFLLFDLLELADCCKVKKLHIIFDKR 2820
Query: 8461 EHPRKTLLQHNLGEFQGPAIVAILEGVTLTREEICSLQLLSQWRIKGETLNYGLGLLSCY 8640
EHPRKTLLQHNLGEFQGPAIVAILEGVTLTREEICSLQLLSQWRIKGETLNYGLGLLSCY
Sbjct: 2821 EHPRKTLLQHNLGEFQGPAIVAILEGVTLTREEICSLQLLSQWRIKGETLNYGLGLLSCY 2880
Query: 8641 FMCDLLSIVSGGYFYMFDPQGATLSASTTQAPAGKMFSLIGTNLVERFSDQFNPMLIGQD 8820
FMCDLLSIVSGGYFYMFDPQGATLSASTTQAPAGKMFSLIGTNLVERFSDQFNPMLIGQD
Sbjct: 2881 FMCDLLSIVSGGYFYMFDPQGATLSASTTQAPAGKMFSLIGTNLVERFSDQFNPMLIGQD 2940
Query: 8821 KAWSLTDSTIIRMPLSTEILKDGFEAGLDRVKQISDQFLENASRILIFLKSVSQVSFSTW 9000
KAWSLTDSTIIRMPLSTEILKDGFEAGLDRVKQISDQFLENASRILIFLKSVSQVSFSTW
Sbjct: 2941 KAWSLTDSTIIRMPLSTEILKDGFEAGLDRVKQISDQFLENASRILIFLKSVSQVSFSTW 3000
Query: 9001 EQGNAQPHQDYTLHIDSASAIMRNPFAEKNLKTSKLSRIFGSSNSGVKSRIIEVNLHIGE 9180
EQGNAQPHQDYTLHIDSASAIMRNPFAEKNLKTSKLSRIFGSSNSGVKSRIIEVNLHIGE
Sbjct: 3001 EQGNAQPHQDYTLHIDSASAIMRNPFAEKNLKTSKLSRIFGSSNSGVKSRIIEVNLHIGE 3060
Query: 9181 NKLLDRWLVVLSKGSGQSQNMARGRKYLAYNLTPVAGVAAHVSRNGRPVDVHAASPIMSP 9360
NKLLDRWLVVLSKGSGQSQNMARGRKYLAYNLTPVAGVAAHVSRNGRPVDVHAASPIMSP
Sbjct: 3061 NKLLDRWLVVLSKGSGQSQNMARGRKYLAYNLTPVAGVAAHVSRNGRPVDVHAASPIMSP 3120
Query: 9361 LPLSGSVNLPVTILGCFLIRNNCGRFLFKNKNERAMSEPQLDAGDILIDAWNKELMSCVR 9540
LPLSGSVNLPVTILGCFLIRNNCGRFLFKNKNERAMSEPQLDAGDILIDAWNKELMSCVR
Sbjct: 3121 LPLSGSVNLPVTILGCFLIRNNCGRFLFKNKNERAMSEPQLDAGDILIDAWNKELMSCVR 3180
Query: 9541 DSYIEIVVXXXXXXXXXXXXXXXXXXARQLALSLKAYGHQLYSFWPRSNQHDDAIEAEVL 9720
DSYIEIVV ARQLALSLKAYGHQLYSFWPRSNQHDDAIEAEVL
Sbjct: 3181 DSYIEIVVEMERLSREHSSSSTESSTARQLALSLKAYGHQLYSFWPRSNQHDDAIEAEVL 3240
Query: 9721 KPEWECLVEQVIRPFYARVADLPLWQLYSGSLVKAEEGMFLTQPGSEVAVNLLPLTVCSF 9900
KPEWECLVEQVIRPFYARVADLPLWQLYSGSLVKAEEGMFLTQPGSEVAVNLLPLTVCSF
Sbjct: 3241 KPEWECLVEQVIRPFYARVADLPLWQLYSGSLVKAEEGMFLTQPGSEVAVNLLPLTVCSF 3300
Query: 9901 VKEHYPVFSVPWELLAEVQAVGIPVREVKPKMVRVLLRKSSASIDLRSVDTFIDVLEYCL 10080
VKEHYPVFSVPWELLAEVQAVGIPVREVKPKMVRVLLRKSSASIDLRSVDTFIDVLEYCL
Sbjct: 3301 VKEHYPVFSVPWELLAEVQAVGIPVREVKPKMVRVLLRKSSASIDLRSVDTFIDVLEYCL 3360
Query: 10081 SDIQFIEALNPEEANMDEGNXXXXXXXXXXXXXXXXXDAFEMMTSLGKALFDFGRVVVED 10260
SDIQFIEALNPEEANMDEGN DAFEMMTSLGKALFDFGRVVVED
Sbjct: 3361 SDIQFIEALNPEEANMDEGNSTSTSSSMSTQAQAGSSDAFEMMTSLGKALFDFGRVVVED 3420
Query: 10261 IGRTGDSIGQRISNNRYSNADPRFLSAVNELKGLPCPTATNHLARLGISELWLGNKEQQA 10440
IGRTGDSIGQRISNNRYSNADPRFLSAVNELKGLPCPTATNHLARLGISELWLGNKEQQA
Sbjct: 3421 IGRTGDSIGQRISNNRYSNADPRFLSAVNELKGLPCPTATNHLARLGISELWLGNKEQQA 3480
Query: 10441 LMLPVSARFIHPKVFERSSLADIFLKSSVQAFLKLRSWSLPLLASNMKYLFHDHWVSYIS 10620
LMLPVSARFIHPKVFERSSLADIFLKSSVQAFLKLRSWSLPLLASNMKYLFHDHWVSYIS
Sbjct: 3481 LMLPVSARFIHPKVFERSSLADIFLKSSVQAFLKLRSWSLPLLASNMKYLFHDHWVSYIS 3540
Query: 10621 ESNSVPWFXXXXXXXXXXXXXXXXXXIQLFWKNFNGSADELSLFSDWPLIPAFLGRPILC 10800
ESNSVPWF IQLFWKNFNGSADELSLFSDWPLIPAFLGRPILC
Sbjct: 3541 ESNSVPWFSWESTSSSSDDSGPSPEWIQLFWKNFNGSADELSLFSDWPLIPAFLGRPILC 3600
Query: 10801 RVRERHLIFFPPPALQPVSRSGTDMHQTDSDISTTSVSGGPLSELTQRYVSGFDLAQSKH 10980
RVRERHLIFFPPPALQPVSRSGTDMHQTDSDISTTSVSGGPLSELTQRYVSGFDLAQSKH
Sbjct: 3601 RVRERHLIFFPPPALQPVSRSGTDMHQTDSDISTTSVSGGPLSELTQRYVSGFDLAQSKH 3660
Query: 10981 PWLILLLNQCNIPVCDTAYIDCAERCKCLPSPSVSLGQAIASKLAEGKRAGYIADIASFP 11160
PWLILLLNQCNIPVCDTAYIDCAERCKCLPSPSVSLGQAIASKLAEGKRAGYIADIASFP
Sbjct: 3661 PWLILLLNQCNIPVCDTAYIDCAERCKCLPSPSVSLGQAIASKLAEGKRAGYIADIASFP 3720
Query: 11161 TFGRDELFTLLANDFSSSGSSYQAYELEVLSSLPIFKTVTGSYTHLQRHGLCIISGDSFL 11340
TFGRDELFTLLANDFSSSGSSYQAYELEVLSSLPIFKTVTGSYTHLQRHGLCIISGDSFL
Sbjct: 3721 TFGRDELFTLLANDFSSSGSSYQAYELEVLSSLPIFKTVTGSYTHLQRHGLCIISGDSFL 3780
Query: 11341 KPYDECCFCYLPDSVECHFLQALGVTVLHNHQTLVRFGLAEFESRSQSEREDILIYVYGN 11520
KPYDECCFCYLPDSVECHFLQALGVTVLHNHQTLVRFGLAEFESRSQSEREDILIYVYGN
Sbjct: 3781 KPYDECCFCYLPDSVECHFLQALGVTVLHNHQTLVRFGLAEFESRSQSEREDILIYVYGN 3840
Query: 11521 WLDLEVDSDVIEALREAKFVRNSDEFSSELSKSKDLFDPSDTLLVSVFFGERKRFPGERF 11700
WLDLEVDSDVIEALREAKFVRNSDEFSSELSKSKDLFDPSDTLLVSVFFGERKRFPGERF
Sbjct: 3841 WLDLEVDSDVIEALREAKFVRNSDEFSSELSKSKDLFDPSDTLLVSVFFGERKRFPGERF 3900
Query: 11701 SSEGWLRILRKAGLRTAAEADVILECAKRVEFLGNERNRSSEEDDFETDLVHSEKDISVE 11880
SSEGWLRILRKAGLRTAAEADVILECAKRVEFLGNERNRSSEEDDFETDLVHSEKDISVE
Sbjct: 3901 SSEGWLRILRKAGLRTAAEADVILECAKRVEFLGNERNRSSEEDDFETDLVHSEKDISVE 3960
Query: 11881 LSTLAGSVIEAILLNFAGFYSTAFCNTLGQIACVPAESGFPSLGGRKGGKRVLTRYSEAV 12060
LSTLAGSVIEAILLNFAGFYSTAFCNTLGQIACVPAESGFPSLGGRKGGKRVLTRYSEAV
Sbjct: 3961 LSTLAGSVIEAILLNFAGFYSTAFCNTLGQIACVPAESGFPSLGGRKGGKRVLTRYSEAV 4020
Query: 12061 LLRDWPLAWSSVPILSTQRFIPPGFSWTALRLKSPPIFSTVLKHLQVIGRNGGEDTLAHW 12240
LLRDWPLAWSSVPILSTQRFIPPGFSWTALRLKSPPIFSTVLKHLQVIGRNGGEDTLAHW
Sbjct: 4021 LLRDWPLAWSSVPILSTQRFIPPGFSWTALRLKSPPIFSTVLKHLQVIGRNGGEDTLAHW 4080
Query: 12241 PNDPNVMTIDVTSCEVLKYLEIVWDSLTTSDILELQKVAFLPAANGTRLVGASSLFVRLP 12420
PNDPNVMTIDVTSCEVLKYLEIVWDSLTTSDILELQKVAFLPAANGTRLVGASSLFVRLP
Sbjct: 4081 PNDPNVMTIDVTSCEVLKYLEIVWDSLTTSDILELQKVAFLPAANGTRLVGASSLFVRLP 4140
Query: 12421 INLSPFAFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSKLQKLCGYRRLNPNELRAVM 12600
INLSPFAFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSKLQKLCGYRRLNPNELRAVM
Sbjct: 4141 INLSPFAFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSKLQKLCGYRRLNPNELRAVM 4200
Query: 12601 EILHFLCDEINTTKPPEINTIKSDVIVPDDGCRLVHALSCVYVDSFGSRYVRYIDTARLR 12780
EILHFLCDEINTTKPPEINTIKSDVIVPDDGCRLVHALSCVYVDSFGSRYVRYIDTARLR
Sbjct: 4201 EILHFLCDEINTTKPPEINTIKSDVIVPDDGCRLVHALSCVYVDSFGSRYVRYIDTARLR 4260
Query: 12781 LVHPLLPERICLDLGVRKLSDVVIEELENAEHIETLDNIGSISLKAVRRKLQSETFQAAL 12960
LVHPLLPERICLDLGVRKLSDVVIEELENAEHIETLDNIGSISLKAVRRKLQSETFQAAL
Sbjct: 4261 LVHPLLPERICLDLGVRKLSDVVIEELENAEHIETLDNIGSISLKAVRRKLQSETFQAAL 4320
Query: 12961 WTVSRQATTVDDLSFEVMQHSLQSAAEKIGFVRNIYTRFLLLPNSVDVTFVAKESMIPEW 13140
WTVSRQATTVDDLSFEVMQHSLQSAAEKIGFVRNIYTRFLLLPNSVDVTFVAKESMIPEW
Sbjct: 4321 WTVSRQATTVDDLSFEVMQHSLQSAAEKIGFVRNIYTRFLLLPNSVDVTFVAKESMIPEW 4380
Query: 13141 ENESHHRTMYFINRHRTSILVSEPPGYISFLDVMATVVSEVLGFPTSLPIGSLFSCPEGS 13320
ENESHHRTMYFINRHRTSILVSEPPGYISFLDVMATVVSEVLGFPTSLPIGSLFSCPEGS
Sbjct: 4381 ENESHHRTMYFINRHRTSILVSEPPGYISFLDVMATVVSEVLGFPTSLPIGSLFSCPEGS 4440
Query: 13321 ETEITAYLRLCSYSLTNTGTADSSVGQEIMPQDAVQVQLHPLRPFYKGEIVAWKIKQGDK 13500
ETEITAYLRLCSYSLTNTGTADSSVGQEIMPQDAVQVQLHPLRPFYKGEIVAWKIKQGDK
Sbjct: 4441 ETEITAYLRLCSYSLTNTGTADSSVGQEIMPQDAVQVQLHPLRPFYKGEIVAWKIKQGDK 4500
Query: 13501 LRYGRVPEDVRPSAGQALYRLKVEMTPGETGLLLSSQVFSFRGTSIENEGPSTLPEVLPA 13680
LRYGRVPEDVRPSAGQALYRLKVEMTPGETGLLLSSQVFSFRGTSIENEGPSTLPEVLPA
Sbjct: 4501 LRYGRVPEDVRPSAGQALYRLKVEMTPGETGLLLSSQVFSFRGTSIENEGPSTLPEVLPA 4560
Query: 13681 VSDKKSQEIXXXXXXXXXXXXQPVNEMQLGRVTAKELVEAVHEMLSAAGINMELENQSXX 13860
VSDKKSQEI QPVNEMQLGRVTAKELVEAVHEMLSAAGINMELENQS
Sbjct: 4561 VSDKKSQEISESSRTNKTSSSQPVNEMQLGRVTAKELVEAVHEMLSAAGINMELENQSLL 4620
Query: 13861 XXXXXXXXXXKDSKVAFLLEQERAEASMKEAETAKSQWLCQICQTKEVEVTIVPCGHVLC 14040
KDSKVAFLLEQERAEASMKEAETAKSQWLCQICQTKEVEVTIVPCGHVLC
Sbjct: 4621 QRTLTLQEELKDSKVAFLLEQERAEASMKEAETAKSQWLCQICQTKEVEVTIVPCGHVLC 4680
Query: 14041 RHCSTSVSRCPFCRLQVNRTIRIFRP 14118
RHCSTSVSRCPFCRLQVNRTIRIFRP
Sbjct: 4681 RHCSTSVSRCPFCRLQVNRTIRIFRP 4706
>gb|AAM97006.1| putative protein [Arabidopsis thaliana]|gi|23197908|gb|AAN15481.1|
putative protein [Arabidopsis thaliana]
Length = 620
Score = 1170 bits (3028), Expect = 0.0
Identities = 596/620 (96%), Positives = 596/620 (96%)
Frame = +1
Query: 12259 MTIDVTSCEVLKYLEIVWDSLTTSDILELQKVAFLPAANGTRLVGASSLFVRLPINLSPF 12438
MTIDVTSCEVLKYLEIVWDSLTTSDILELQKVAFLPAANGTRLVGASSLFVRLPINLSPF
Sbjct: 1 MTIDVTSCEVLKYLEIVWDSLTTSDILELQKVAFLPAANGTRLVGASSLFVRLPINLSPF 60
Query: 12439 AFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSKLQKLCGYRRLNPNELRAVMEILHFL 12618
AFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSKLQKLCGYRRLNPNELRAVMEILHFL
Sbjct: 61 AFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSKLQKLCGYRRLNPNELRAVMEILHFL 120
Query: 12619 CDEINTTKPPEINTIKSDVIVPDDGCRLVHALSCVYVDSFGSRYVRYIDTARLRLVHPLL 12798
CDEINTTKPPEINTIKSDVIVPDDGCRLVHALSCVYVDSFGSRYVRYIDTARLRLVHPLL
Sbjct: 121 CDEINTTKPPEINTIKSDVIVPDDGCRLVHALSCVYVDSFGSRYVRYIDTARLRLVHPLL 180
Query: 12799 PERICLDLGVRKLSDVVIEELENAEHIETLDNIGSISLKAVRRKLQSETFQAALWTVSRQ 12978
PERICLDLGVRKLSDVVIEELENAEHIETLDNIGSISLKAVRRKLQSETFQAALWTVSRQ
Sbjct: 181 PERICLDLGVRKLSDVVIEELENAEHIETLDNIGSISLKAVRRKLQSETFQAALWTVSRQ 240
Query: 12979 ATTVDDLSFEVMQHSLQSAAEKIGFVRNIYTRFLLLPNSVDVTFVAKESMIPEWENESHH 13158
ATTVDDLSFEVMQHSLQSAAEKIGFVRNIYTRFLLLPNSVDVTFVAKESMIPEWENESHH
Sbjct: 241 ATTVDDLSFEVMQHSLQSAAEKIGFVRNIYTRFLLLPNSVDVTFVAKESMIPEWENESHH 300
Query: 13159 RTMYFINRHRTSILVSEPPGYISFLDVMATVVSEVLGFPTSLPIGSLFSCPEGSETEITA 13338
RTMYFINRHRTSILVSEPPGYISFLDVMATVVSEVLGFPTSLPIGSLFSCPEGSETEITA
Sbjct: 301 RTMYFINRHRTSILVSEPPGYISFLDVMATVVSEVLGFPTSLPIGSLFSCPEGSETEITA 360
Query: 13339 YLRLCSYSLTNTGTADSSVGQEIMPQDAVQVQLHPLRPFYKGEIVAWKIKQGDKLRYGRV 13518
YLRLCSYSLTNTGTADSSVGQEIMPQDAVQVQLHPLRPFYKGEIVAWKIKQGDKLRYGRV
Sbjct: 361 YLRLCSYSLTNTGTADSSVGQEIMPQDAVQVQLHPLRPFYKGEIVAWKIKQGDKLRYGRV 420
Query: 13519 PEDVRPSAGQALYRLKVEMTPGETGLLLSSQVFSFRGTSIENEGPSTLPEVLPAVSDKKS 13698
PEDVRPSAGQALYRLKVEMTPGETGLLLSSQVFSFRGTSIENEGPSTLPEVLPAVSDKKS
Sbjct: 421 PEDVRPSAGQALYRLKVEMTPGETGLLLSSQVFSFRGTSIENEGPSTLPEVLPAVSDKKS 480
Query: 13699 QEIXXXXXXXXXXXXQPVNEMQLGRVTAKELVEAVHEMLSAAGINMELENQSXXXXXXXX 13878
QEI QPVNEMQLGRVTAKELVEAVHEMLSAAGINMELENQS
Sbjct: 481 QEISESSRTNKTSSSQPVNEMQLGRVTAKELVEAVHEMLSAAGINMELENQSLLQRTLTL 540
Query: 13879 XXXXKDSKVAFLLEQERAEASMKEAETAKSQWLCQICQTKEVEVTIVPCGHVLCRHCSTS 14058
KDSKVAFLLEQERAEASMKEAETAKSQWLCQICQTKEVEVTIVPCGHVLCRHCSTS
Sbjct: 541 QEELKDSKVAFLLEQERAEASMKEAETAKSQWLCQICQTKEVEVTIVPCGHVLCRHCSTS 600
Query: 14059 VSRCPFCRLQVNRTIRIFRP 14118
VSRCPFCRLQVNRTIRIFRP
Sbjct: 601 VSRCPFCRLQVNRTIRIFRP 620
Score = 43.5 bits (101), Expect = 0.096
Identities = 53/245 (21%), Positives = 95/245 (38%), Gaps = 16/245 (6%)
Frame = +1
Query: 3637 PLQLVPYIRVIPTDLAVFRGLFVELGVREFLTPSDYADVLCRIAVRKGTSPLDPQEIRAA 3816
P+ L P+ +P+ F + +LG+ + L+ + D+L ++ G L+P E+RA
Sbjct: 54 PINLSPFAFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSKLQKLCGYRRLNPNELRAV 113
Query: 3817 VLIAQQLAEAQFLD--------KVTIYLPDVSGRLFPSSDLVYNDAPWLTASDNLNSSFS 3972
+ I L + K + +PD RL + VY D SF
Sbjct: 114 MEILHFLCDEINTTKPPEINTIKSDVIVPDDGCRLVHALSCVYVD------------SFG 161
Query: 3973 AESTMLLNAKRTMQKFVHGNISNEVAEKLGVRSLRRVLL--------AESADSMNFSLSG 4128
+ ++ R + VH + + LGVR L V++ E+ D++
Sbjct: 162 SRYVRYIDTARL--RLVHPLLPERICLDLGVRKLSDVVIEELENAEHIETLDNIGSISLK 219
Query: 4129 AAEAFGQHEALTTRLKHILEMYADGPGILFELVQNAEDAGASEVTFLLDKTHYGTSSLLS 4308
A Q E L + + FE++Q++ + A ++ F+ + T LL
Sbjct: 220 AVRRKLQSETFQAALWTVSRQATTVDDLSFEVMQHSLQSAAEKIGFV---RNIYTRFLLL 276
Query: 4309 PEMAD 4323
P D
Sbjct: 277 PNSVD 281
>ref|NP_055178.1| spastic ataxia of Charlevoix-Saguenay (sacsin) [Homo
sapiens]|gi|13124523|sp|Q9NZJ4|SACS_HUMAN
Sacsin|gi|6907042|gb|AAF31262.1|AF193556_1 sacsin [Homo
sapiens]
Length = 3829
Score = 266 bits (680), Expect = 7e-69
Identities = 279/1029 (27%), Positives = 434/1029 (42%), Gaps = 36/1029 (3%)
Frame = +1
Query: 2530 KHLPPLDVPACL-LGCEFILCCQGSEEDVLSRYYGIERMRKSNFYRQNVFNRIEVLQPEI 2706
K+L +++P+ + LG E C Q E+ S + F+ + F I+ ++ E+
Sbjct: 1272 KNLCAVELPSSVKLGFEEAGCKQILLENTFS---------EKQFFSEVFFPNIQEIEAEL 1322
Query: 2707 RDQVMISILQDLPXXXXXXXXXXXXXXXXXFVP-TVNG-PLKRPSVLHDPRNEELYALLE 2880
RD +MI +L + +P ++ G PL PS L P
Sbjct: 1323 RDPLMIFVLNE------KVDEFSGVLRVTPCIPCSLEGHPLVLPSRLIHPEGRVAKLFDI 1376
Query: 2881 DSDCFPASGFQ---GSAILDMLQGLGL-KTTVSPETILESARLVERLMHKDLEKAHSRGK 3048
FP Q IL L LG+ K + + +LE A V + D A R
Sbjct: 1377 KDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAVSVAEINKSDHVAACLRSS 1436
Query: 3049 VLFSFLEVNAVKWLPDQSSEDDGAINRIFSRAATAFRPRNLTCNLVKFWSELKMICWCPV 3228
+L S ++ + D ++D F ++ + I + P
Sbjct: 1437 ILLSLIDEKLK--IRDPRAKD--------------------------FAAKYQTIRFLPF 1468
Query: 3229 LVSAPFQTLPWPVVTSTVAPPKLVRPKTDMW------LVSASMRILDGE------CSSTA 3372
L +L W P+ + TD++ +V IL+ C S +
Sbjct: 1469 LTKPAGFSLDWK---GNSFKPETMFAATDLYTAEHQDIVCLLQPILNENSHSFRGCGSVS 1525
Query: 3373 LAYN--LGWLSHPGGSAIAAQLLELGKNNEILIDQVLRQELALAMPKIYSILARLLGSDE 3546
LA LG L P + QL E+ K+ +D + Y L L +E
Sbjct: 1526 LAVKEFLGLLKKPTVDLVINQLKEVAKS----VDDGITLYQENITNACYKYLHEALMQNE 1581
Query: 3547 MDIVKAV--LEGSRWIWVGDGFATLSEVVLDGPLQLVPYIRVIPTDLAV-FRGLFVELGV 3717
+ + + L+ +I V + + +V + PY+ +P FR LF +GV
Sbjct: 1582 ITKMSIIDKLKPFSFILVENAYVDSEKVSFHLNFEAAPYLYQLPNKYKNNFRELFETVGV 1641
Query: 3718 REFLTPSDYADVLCRIAVRKGTSPLDPQEIRAAVLIAQQ-------LAEAQFLDKV--TI 3870
R+ T D+A VL I +GT + + + I + + +F +K I
Sbjct: 1642 RQSCTVEDFALVLESIDQERGTKQITEENFQLCRRIISEGIWSLIREKKQEFCEKNYGKI 1701
Query: 3871 YLPDVSGRLFPSSDLVYNDAPWLTASDNLNSSFSAESTMLLNAKRTMQKFVHGNISNEVA 4050
LPD + L P+ L YND PW+ D T K+ H +I EVA
Sbjct: 1702 LLPDTNLMLLPAKSLCYNDCPWIKVKD------------------TTVKYCHADIPREVA 1743
Query: 4051 EKLGVRSLRRVLLAESADSMNFSLSGAAEAFGQHEALTTRLKHILEMYADGPGILFELVQ 4230
KLG R L A ++ F+ G FGQ E LT+R+K IL Y +L EL+Q
Sbjct: 1744 VKLGAVPKRHKALERYASNVCFTTLGTE--FGQKEKLTSRIKSILNAYPSEKEMLKELLQ 1801
Query: 4231 NAEDAGASEVTFLLDKTHYGTSSLLSPEMADWQGPALYCFNNSVFTQQDMYAISRIGQAS 4410
NA+DA A+E+ F+ D + + + A QGPAL +NN FT+ D+ I +G+ +
Sbjct: 1802 NADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKGT 1861
Query: 4411 KLEKPFAIGRFGLGFNCVYHFTDIPGFVSGENIV-MFDPHANHLPGISPTHPGLRIKFAG 4587
K P+ G++G+GFN VYH TD P F+SG +I+ +FDPHA + PG + PG +
Sbjct: 1862 KEGNPYKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSISPGRMFRDLD 1921
Query: 4588 RYILDQFPDQFAPFL--HFGCDLEHTFPGTLFRFPLRNASVAPRSHIKKETYAPEDVLSL 4761
QF D +L HF D T+FRFPLRNA +A S I + V +L
Sbjct: 1922 ADFRTQFSDVLDLYLGTHFKLD-----NCTMFRFPLRNAEMAKVSEISSVPASDRMVQNL 1976
Query: 4762 FTSFSGVVSEALIFLRNVKTVSIFTKEGAGHEMQLLHRVCKDHNVGQDTEPKPSSQVFSL 4941
+E L+FL +++ +SI + + + +L+ V G+ T+
Sbjct: 1977 LDKLRSDGAELLMFLNHMEKISICEIDKSTGALNVLYSV-----KGKITDG-------DR 2024
Query: 4942 LDENIFAGMNKDQLLKKLSNTVVKDLPYKCQKIVVTEQDSSGCILHGWITGECLNAGVSK 5121
L F D + KK +KD+P + + +DS G L W+ C +G S
Sbjct: 2025 LKRKQFHASVIDSVTKKRQ---LKDIPVQQITYTMDTEDSEG-NLTTWLI--CNRSGFS- 2077
Query: 5122 KNLNLPEMSHKLIPWASVAVHINSVKNENVEDLAASISNIFGPSTISIQNRRNFGGRAFC 5301
++ ++S + I++ KN+++ G I + RAFC
Sbjct: 2078 ---SMEKVSKSV---------ISAHKNQDITLFPR------GGVAACITHNYKKPHRAFC 2119
Query: 5302 FLPLPITTGLPAHINAYFELSSNRRDLWFGNDMAGDGKVRSDWNLYLIEEVVVPAYGHLL 5481
FLPL + TGLP H+N +F L S RR+LW ++ G VRSDWN L+ ++ PAY LL
Sbjct: 2120 FLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVG---VRSDWNNSLMTALIAPAYVELL 2176
Query: 5482 EKIASELGP 5508
++ P
Sbjct: 2177 IQLKKRYFP 2185
Score = 261 bits (667), Expect = 2e-67
Identities = 341/1345 (25%), Positives = 553/1345 (40%), Gaps = 112/1345 (8%)
Frame = +1
Query: 1990 ISWHP-ESNRDHPSSSWFVLFWQYLDKR-CQSLSLFCDWPILPSTS--------GYLYIA 2139
+ W+P + NR+HPS SW + W+ L + L+LF + P++P T + +
Sbjct: 12 VQWYPFDENRNHPSVSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTILEEGQTCVELIRLR 71
Query: 2140 SPQSKLINAE---KLPAAVRNVLEKIGGKILNN-NIKVEHSDLSSFVSDASYTGVLESIF 2307
P +++ E +LP + ++++K+GG +L + ++H + ++ + VL+ +
Sbjct: 72 IPSLVILDDESEAQLPEFLADIVQKLGGFVLKKLDASIQHPLIKKYIHSPLPSAVLQIM- 130
Query: 2308 DAASSDLDGVQNLIYDLNAQEKDELRSFLLDPKWHIGHQIGDLYLRICKILPIHRIYGET 2487
L + N I L KD LR FL + RI + L I + +
Sbjct: 131 --EKMPLQKLCNQITSLLPTHKDALRKFLASLT-----DSSEKEKRIIQELAIFKRINHS 183
Query: 2488 SAQE-SKYSDLVNPPKHLPPLDVPACLLGCEFILCCQGSEEDVLSRYYGIERMRKSNFYR 2664
S Q S Y+ L +PA L ++ L+ IE+++ ++ +
Sbjct: 184 SDQGISSYTKLKGCKVLHHTAKLPADLRLSISVIDSSDEATIRLANMLKIEQLKTTSCLK 243
Query: 2665 QNVFNRIE--VLQPEIRDQVMISILQDLPXXXXXXXXXXXXXXXXXFVPTVNGPLKRPSV 2838
V IE E Q+M+ +L++L F+ +
Sbjct: 244 L-VLKDIENAFYSHEEVTQLMLWVLENLSSLKNENPNVLEWLTPLKFIQISQEQMVSAGE 302
Query: 2839 LHDPRNEELYALL--EDSDCFPASGFQGSAILDMLQGLGLKTTVS--PETILESARLVER 3006
L DP E L L E+ FP S F IL L+ +GLK S + +++ A+ +E
Sbjct: 303 LFDPDIEVLKDLFCNEEGTYFPPSVFTSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEA 362
Query: 3007 LMH---KDLEKAHSRGKVLFSFLEVNAVKWLPDQSSEDDGAINRIFSRAATAFRPRNLTC 3177
L D + + K L L N QSSE + +I A RP N
Sbjct: 363 LQVGACPDQDVLLKKAKTLLLVLNKNHTLL---QSSEGKMTLKKIKWVPACKERPPNYPG 419
Query: 3178 NLVKFWS-ELKMICWCPVLVSAPFQTLPWPVVTSTVAPPKLVRPKTDMWLVSASMRILDG 3354
+LV W +L +C APP + + L+ +S+ ++
Sbjct: 420 SLV--WKGDLCNLC----------------------APPDMCDVGHAI-LIGSSLPLV-- 452
Query: 3355 ECSSTALAYNLGWLSHPGGSAIAAQLLELGKNNEILIDQVLRQ--------ELALAMPKI 3510
E L LG + P SA+ K+ +I++D + + + +I
Sbjct: 453 ESIHVNLEKALGIFTKPSLSAVL-------KHFKIVVDWYSSKTFSDEDYYQFQHILLEI 505
Query: 3511 YSILARLL--GSDEMDIVKAVLEGSRWIWVGDGFATLSEVVLDG--PLQLVPYIRVIPTD 3678
Y + L G D +K W+W G F L++ V+ L L PY+ +P
Sbjct: 506 YGFMHDHLNEGKDSFRALKFP-----WVWTGKKFCPLAQAVIKPIHDLDLQPYLHNVPKT 560
Query: 3679 LAVFRGLFVELGVREFLTPSDYADVLCRIAVRKGTSPLDPQEIRAAVLIAQQLAEAQFLD 3858
+A F LF G E LT SD+ ++ + K L QE + + + + + +
Sbjct: 561 MAKFHQLFKVCGSIEELT-SDHISMVIQKIYLKSDQDLSEQESKQNLHLMLNIIRWLYSN 619
Query: 3859 K--------VTIYLPDVSGRLF--PSSDLVYNDAPWLTASDNLNSSFSAESTMLLNAKRT 4008
+ V I+ +L P + Y D +D L S E +L
Sbjct: 620 QIPASPNTPVPIHHSKNPSKLIMKPIHECCYCDIKVDDLNDLLEDS--VEPIIL------ 671
Query: 4009 MQKFVHGNISNEVAEKLGVRSLRRVLLAESADSMNFSLSGAAEAFGQHEALTTRLKHILE 4188
VH +I + AE L V L L+ + ++M F SG Q E LT R+K+ILE
Sbjct: 672 ----VHEDIPMKTAEWLKVPCLSTRLI--NPENMGFEQSG------QREPLTVRIKNILE 719
Query: 4189 MYADGPGILFELVQNAEDAGASEVTFLLDKTHYGT--SSLLSPEMADWQGPALYCFNNSV 4362
Y I EL+QNA+DA A+E +FL+D +LL P MA GPAL+ FNNS
Sbjct: 720 EYPSVSDIFKELLQNADDANATECSFLIDMRRNMDIRENLLDPGMAACHGPALWSFNNSQ 779
Query: 4363 FTQQDMYAISRIGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFVSGENIVMFDPHANHLP 4542
F+ D I+R+G++ K + +G+FGLGFN VYH TDIP +S E ++MFDP+ NH+
Sbjct: 780 FSDSDFVNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHIS 839
Query: 4543 G--ISPTHPGLRIKFAGRY-ILDQFPDQFAPFLH-FGCDL------EHTFPGTLFRFPLR 4692
++PG++I ++ + L +FP+QF PF+ FGC L +++ GTLFR R
Sbjct: 840 KHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLTVEAPYSYNGTLFRLSFR 899
Query: 4693 NASVAPRSHIKKETYAPEDVLSLFTSFSGVVSEALIFLRNVK------------------ 4818
A S + Y D+ SL FS +IF ++VK
Sbjct: 900 TQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVKSMYLKYLKIEETNPSLAQ 959
Query: 4819 -TVSIFTKEGAG-----------HEMQLLHRVCKDHNVGQDTEPKPSSQVFSL------- 4941
TV I K + E L + C N ++ SS + +
Sbjct: 960 DTVIIKKKSCSSKALNTPVLSVLKEAAKLMKTCSSSNKKLPSDEPKSSCILQITVEEFHH 1019
Query: 4942 -------LDENIFAGMNKD-QLLKKLSNTVVKDLPYKCQKIVVTEQDSSGCILHGWITGE 5097
L +F G + D L +++ + P Q + C W+
Sbjct: 1020 VFRRIADLQSPLFRGPDDDPAALFEMAKSGQSKKPSD-----ELSQKTVECTT--WLLCT 1072
Query: 5098 CLNAGVSKKNLNLPEMSHK--LIPWASVAVHINSVKNENVEDLAASISNIFGPSTISIQN 5271
C++ G + K +L E + L+P +V V ++ ++++
Sbjct: 1073 CMDTGEALK-FSLSESGRRLGLVPCGAVGVQLSEIQDQK-------------------WT 1112
Query: 5272 RRNFGGRAFCFLPLPITTGLPAHINAYFELSSNRRDLWFGNDMAGDGKVRSDWNLYLIEE 5451
+ G FC+LPL I TGLP HIN F ++SNR+++W D K R WN +
Sbjct: 1113 VKPHIGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIW-----KTDTKGR--WNTTFMRH 1165
Query: 5452 VVVPAYGHLLEKIASELGPCDL----FFSVWP-VTLGTEPWASLVRKLYSFIAN-NGLRV 5613
V+V AY +L + +L +++VWP L + ++ + + Y IA+ G +
Sbjct: 1166 VIVKAYLQVLSVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKEL 1225
Query: 5614 LYTKARGGQWISTKQAIYPDFSFPK 5688
+ G W+S K + D S K
Sbjct: 1226 TKVFSDGSTWVSMKNVRFLDDSILK 1250
Score = 236 bits (603), Expect = 6e-60
Identities = 151/430 (35%), Positives = 219/430 (50%), Gaps = 9/430 (2%)
Frame = +1
Query: 22 DFGQKVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLDRRVHGSGSLLSDSL 201
+FGQK LT RI+ +L YP +LKEL+QNADDA AT++ D R H + D
Sbjct: 1771 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKW 1830
Query: 202 AQWQGPSLLAYNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHLTDIPSFVS 381
A QGP+L YN+ FTE+D I +G K G +KTG++G+GFNSVYH+TD PSF+S
Sbjct: 1831 APLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPYKTGQYGIGFNSVYHITDCPSFIS 1890
Query: 382 GKYVV-LFDPQGAYLPNISAANPGKRIDYVGSSALSQYKDQFLPYCA--FGCDMRSPFNG 552
G ++ +FDP Y P ++ +PG+ + + +Q+ D Y F D N
Sbjct: 1891 GNDILCIFDPHARYAPGATSISPGRMFRDLDADFRTQFSDVLDLYLGTHFKLD-----NC 1945
Query: 553 TLFRFPLRNTEQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLFLKCVLSIEMYTWDDG 732
T+FRFPLRN E A S +S + + + D+L +G L+FL + I + D
Sbjct: 1946 TMFRFPLRNAEMAKVSEISSVPASDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKS 2005
Query: 733 DSEPKKLYSCSVSSPNNDTV----WHRQAVLRLSKTSISGDREMDAFTLEFLSESEKGNQ 900
LYS + D + +H + ++K D + T +E +GN
Sbjct: 2006 TGALNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNL 2065
Query: 901 TKRRTDRFYIVQTMASASS--KIGLFAATASKEYDIHLLPWASVAACISDDSSENNILKL 1074
T +++ + SS K+ +A K DI L P VAACI+ +N K
Sbjct: 2066 TT------WLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACIT-----HNYKKP 2114
Query: 1075 GHAFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKVRSAWNRLLLEDVVAPS 1254
AFCFLPL + TGL VNG+F + S RR +W D VRS WN L+ ++AP+
Sbjct: 2115 HRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRD---DNGVGVRSDWNNSLMTALIAPA 2171
Query: 1255 FARLLLCLRE 1284
+ LL+ L++
Sbjct: 2172 YVELLIQLKK 2181
Score = 211 bits (538), Expect = 2e-52
Identities = 157/576 (27%), Positives = 278/576 (48%), Gaps = 76/576 (13%)
Frame = +1
Query: 4 DSLLLEDFGQKVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLD--RRVHGS 177
+++ E GQ+ LT RI+ +L YP + + KEL+QNADDA AT+ +D R +
Sbjct: 697 ENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFLIDMRRNMDIR 756
Query: 178 GSLLSDSLAQWQGPSLLAYNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHL 357
+LL +A GP+L ++N++ F++ DFV+I+R+G S K G+ K G+FG+GFNSVYH+
Sbjct: 757 ENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDKVGKFGLGFNSVYHI 816
Query: 358 TDIPSFVSGKYVVLFDPQGAYLPN--ISAANPGKRIDY-VGSSALSQYKDQFLPYC-AFG 525
TDIP +S +++++FDP ++ +NPG +I++ L ++ +QF P+ FG
Sbjct: 817 TDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDVFG 876
Query: 526 CDM----RSP--FNGTLFRFPLRNTEQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLF 687
C + +P +NGTLFR R ++A S +S Y DI + D+ G ++F
Sbjct: 877 CQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIF 936
Query: 688 LKCVLSIEMYTWDDGDSEPK--------KLYSCSVSSPNNDTVWHRQAVLRLSKTSISGD 843
+ V S+ + ++ P K SCS + N + + +L KT S +
Sbjct: 937 TQSVKSMYLKYLKIEETNPSLAQDTVIIKKKSCSSKALNTPVLSVLKEAAKLMKTCSSSN 996
Query: 844 REMDA----------FTLE-------------------------FLSESEKGNQTKRRTD 918
+++ + T+E L E K Q+K+ +D
Sbjct: 997 KKLPSDEPKSSCILQITVEEFHHVFRRIADLQSPLFRGPDDDPAALFEMAKSGQSKKPSD 1056
Query: 919 RF---------YIVQTMASASSKIGLFAATASKEYDIHLLPWASVAACISDDSSENNILK 1071
+++ T + + + + + L+P +V +S+ + +K
Sbjct: 1057 ELSQKTVECTTWLLCTCMDTGEALKFSLSESGRR--LGLVPCGAVGVQLSEIQDQKWTVK 1114
Query: 1072 --LGHAFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKVRSAWNRLLLEDVV 1245
+G FC+LPL ++TGL V +NG F V+SNR+ IW + R WN + V+
Sbjct: 1115 PHIGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGR-------WNTTFMRHVI 1167
Query: 1246 APSFARLLLCLREVLDSRD----SYFSLWPSGSF-EAPWSILVEQIYKNICNA-----PV 1395
++ ++L LR++ S + +Y+++WP +S++ + Y++I +
Sbjct: 1168 VKAYLQVLSVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTK 1227
Query: 1396 LFSDLDGGKWVSPADAYLHDEEFSGSKDLGDALLQL 1503
+FS DG WVS + D+ +D+G A ++
Sbjct: 1228 VFS--DGSTWVSMKNVRFLDDSILKRRDVGSAAFKI 1261
Score = 125 bits (315), Expect = 1e-26
Identities = 154/690 (22%), Positives = 288/690 (41%), Gaps = 41/690 (5%)
Frame = +1
Query: 7618 LGWMDCLTIDILCRQLIEISKS-------YKEQKSRSSVNPEFESMLQSQIPLLYTRLQE 7776
LG + T+D++ QL E++KS Y+E + + E+++Q++I T++
Sbjct: 1532 LGLLKKPTVDLVINQLKEVAKSVDDGITLYQENITNACYKYLHEALMQNEI----TKMSI 1587
Query: 7777 LSRENDFLALKSALSGVPWVWLGDDFVSADVLSFDSPVKFTPYLYVVPSEL-SDFKELLL 7953
+ + F ++ + + +V ++ +SF + PYLY +P++ ++F+EL
Sbjct: 1588 IDKLKPF----------SFILVENAYVDSEKVSFHLNFEAAPYLYQLPNKYKNNFRELFE 1637
Query: 7954 ELGVRLSFDAADYMNTLQHLQNDIKGSQLTDEQINFVLC---VLEAVADCFXXXXXXXXX 8124
+GVR S D+ L+ + + Q+T+E NF LC + E +
Sbjct: 1638 TVGVRQSCTVEDFALVLESIDQERGTKQITEE--NFQLCRRIISEGIWSLIREKKQEFCE 1695
Query: 8125 XXXXXXXXAG---FLVPLEDLVYNDAPWVDSSSLSGKRFVHPSINSDMANRLGIQSLR-- 8289
L+P + L YND PW+ + K + H I ++A +LG R
Sbjct: 1696 KNYGKILLPDTNLMLLPAKSLCYNDCPWIKVKDTTVK-YCHADIPREVAVKLGAVPKRHK 1754
Query: 8290 ---------CISLVDNDITQDLPCMDFTKLKELLSLYASKXXXXXXXXXXADCCKVKKLH 8442
C + + + Q +++K +L+ Y S+ AD K ++
Sbjct: 1755 ALERYASNVCFTTLGTEFGQKEKLT--SRIKSILNAYPSEKEMLKELLQNADDAKATEIC 1812
Query: 8443 IIFDKREHPRKTLLQHNLGEFQGPAIVAILEGVTLTREEICSLQLLSQWRIKG---ETLN 8613
+FD R+HP + QGPA+ + T +++ +Q L + +G +T
Sbjct: 1813 FVFDPRQHPVDRIFDDKWAPLQGPAL-CVYNNQPFTEDDVRGIQNLGKGTKEGNPYKTGQ 1871
Query: 8614 YGLGLLSCYFMCDLLSIVSGG-YFYMFDPQGATLSASTTQAPAGKMFSLIGTNLVERFSD 8790
YG+G S Y + D S +SG +FDP +T+ +P G+MF + + +FSD
Sbjct: 1872 YGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSISP-GRMFRDLDADFRTQFSD 1930
Query: 8791 QFNPMLIGQDKAWSLTDSTIIRMPL-STEILK----DGFEAGLDRVKQISDQFLENASRI 8955
+ L + L + T+ R PL + E+ K A V+ + D+ + + +
Sbjct: 1931 VLDLYL---GTHFKLDNCTMFRFPLRNAEMAKVSEISSVPASDRMVQNLLDKLRSDGAEL 1987
Query: 8956 LIFLKSVSQVSFSTWEQGNAQPHQDYTL--HIDSASAIMRNPFAEKNLKTSKLSRIFGSS 9129
L+FL + ++S ++ + Y++ I + R F + + R
Sbjct: 1988 LMFLNHMEKISICEIDKSTGALNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQL--K 2045
Query: 9130 NSGVKSRIIEVNLHIGENKLLDRWLVVLSKGSGQ----SQNMARGRKYLAYNLTPVAGVA 9297
+ V+ ++ E L WL+ G S+++ K L P GVA
Sbjct: 2046 DIPVQQITYTMDTEDSEGN-LTTWLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVA 2104
Query: 9298 AHVSRNGRPVDVHAASPIMSPLPLSGSVNLPVTILGCFLIRNNCGRFLFKNKNERAMSEP 9477
A ++ N + H A LPLS LP + G F + ++ R L+++ N
Sbjct: 2105 ACITHNYK--KPHRA---FCFLPLSLETGLPFHVNGHFAL-DSARRNLWRDDN------- 2151
Query: 9478 QLDAGDILIDAWNKELMSC-VRDSYIEIVV 9564
G + WN LM+ + +Y+E+++
Sbjct: 2152 ----GVGVRSDWNNSLMTALIAPAYVELLI 2177
Score = 90.5 bits (223), Expect = 7e-16
Identities = 219/1051 (20%), Positives = 401/1051 (37%), Gaps = 69/1051 (6%)
Frame = +1
Query: 6202 ILWTP--GQRGHPTVEWIRVLWSYLKLS-CDDLSVFSKWPILP---VEDG--C--LMQLI 6351
+ W P R HP+V W++++W L + +DL++F + P++P +E+G C L++L
Sbjct: 12 VQWYPFDENRNHPSVSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTILEEGQTCVELIRLR 71
Query: 6352 LNSNVIRDD----GWSENMSSLLLKCGCRFLNR-ELPVEHPQLETFVQPPTATGILNALL 6516
+ S VI DD E ++ ++ K G L + + ++HP ++ ++ P + +L +
Sbjct: 72 IPSLVILDDESEAQLPEFLADIVQKLGGFVLKKLDASIQHPLIKKYIHSPLPSAVLQIME 131
Query: 6517 AISGGHENIKGIFLNVSEGELHELRNFILQSKWFSGGHMNEVHFETIKHLPIFE--SYRS 6690
+ + + ++ LR F+ S +E I+ L IF+ ++ S
Sbjct: 132 KMP--LQKLCNQITSLLPTHKDALRKFLA-----SLTDSSEKEKRIIQELAIFKRINHSS 184
Query: 6691 RKLVSLNCPVKWLKPDGIREDLLDD---DFVRLDSERERTI-FKRYLQIKEPSKMEFYKA 6858
+ +S +K K L D +DS E TI L+I++ K
Sbjct: 185 DQGISSYTKLKGCKVLHHTAKLPADLRLSISVIDSSDEATIRLANMLKIEQLKTTSCLKL 244
Query: 6859 CVLNRMSEFLSQQEA---LLAILHDLNDLVVADVSLQCAISTTPFVLAANGLWQQPSRLY 7029
+ + + F S +E +L +L +L+ L + ++ ++ F+ + L+
Sbjct: 245 VLKDIENAFYSHEEVTQLMLWVLENLSSLKNENPNVLEWLTPLKFIQISQEQMVSAGELF 304
Query: 7030 DPRVPALQELLHKE--VYFPSEKFSDSKILDALVGLGLR--TTLDCSTYLDAARSVSMLH 7197
DP + L++L E YFP F+ IL +L +GL+ +L + A+ + L
Sbjct: 305 DPDIEVLKDLFCNEEGTYFPPSVFTSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEAL- 363
Query: 7198 DLGDLEASRYGRRLLFHIKTLSIKLSSKTGEANHDESQNIMSITSEDSFDGXXXXXXXXX 7377
+ A LL KTL + L+ NH
Sbjct: 364 ---QVGACPDQDVLLKKAKTLLLVLNK-----NH-------------------------- 389
Query: 7378 XXXLGSLLTQQSEDEFWCQLRSIPWCPICLDPPIE---GIPWL-ESSNLVASPDRVRPKS 7545
L Q SE + L+ I W P C + P + W + NL A PD +
Sbjct: 390 ------TLLQSSEGKM--TLKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPD-MCDVG 440
Query: 7546 QMFLVSATMHLLDGECQSSYLHQKLGWMDCLTIDILCRQLIEISKSYKEQKSRSSVNPEF 7725
L+ +++ L+ E L + LG ++ + + + Y + +F
Sbjct: 441 HAILIGSSLPLV--ESIHVNLEKALGIFTKPSLSAVLKHFKIVVDWYSSKTFSDEDYYQF 498
Query: 7726 ESMLQSQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDF--VSADVLSFDSPVKFT 7899
+ +L ++ L E ++ F ALK PWVW G F ++ V+ +
Sbjct: 499 QHILLEIYGFMHDHLNE--GKDSFRALK-----FPWVWTGKKFCPLAQAVIKPIHDLDLQ 551
Query: 7900 PYLYVVPSELSDFKELLLELG--VRLSFDAADYMNTLQHLQNDIKGSQLTDEQ-INFVLC 8070
PYL+ VP ++ F +L G L+ D + +L++D S+ +Q ++ +L
Sbjct: 552 PYLHNVPKTMAKFHQLFKVCGSIEELTSDHISMVIQKIYLKSDQDLSEQESKQNLHLMLN 611
Query: 8071 VLE-AVADCFXXXXXXXXXXXXXXXXXAGFLVPLEDLVYNDAPWVD-----SSSLSGKRF 8232
++ ++ + P+ + Y D D S+
Sbjct: 612 IIRWLYSNQIPASPNTPVPIHHSKNPSKLIMKPIHECCYCDIKVDDLNDLLEDSVEPIIL 671
Query: 8233 VHPSINSDMANRLGIQ--SLRCISLVDNDITQDLPCMDFT-KLKELLSLYASKXXXXXXX 8403
VH I A L + S R I+ + Q T ++K +L Y S
Sbjct: 672 VHEDIPMKTAEWLKVPCLSTRLINPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKEL 731
Query: 8404 XXXADCCKVKKLHIIFDKREHP--RKTLLQHNLGEFQGPAIVAILEGVTLTREEICSLQL 8577
AD + + D R + R+ LL + GPA+ + + + ++
Sbjct: 732 LQNADDANATECSFLIDMRRNMDIRENLLDPGMAACHGPALWS-FNNSQFSDSDFVNITR 790
Query: 8578 LSQWRIKGE---TLNYGLGLLSCYFMCDLLSIVSGGYFYMFDPQGATLS--ASTTQAPAG 8742
L + +GE +GLG S Y + D+ I+S + MFDP +S P
Sbjct: 791 LGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGI 850
Query: 8743 KMFSLIGTNLVERFSDQFNPMLIGQDKAWSLT-------DSTIIRMPLSTEILKDGFEA- 8898
K+ + +F +QF P + LT + T+ R+ T+ E
Sbjct: 851 KINWSKQQKRLRKFPNQFKPFIDVFGCQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVS 910
Query: 8899 ----GLDRVKQISDQFLENASRILIFLKSVSQ--VSFSTWEQGNAQPHQDYTL--HIDSA 9054
+ + D+F R++IF +SV + + E+ N QD + +
Sbjct: 911 STCYNTADIYSLVDEFSLCGHRLIIFTQSVKSMYLKYLKIEETNPSLAQDTVIIKKKSCS 970
Query: 9055 SAIMRNPFAEKNLKTSKLSRIFGSSNSGVKS 9147
S + P + +KL + SSN + S
Sbjct: 971 SKALNTPVLSVLKEAAKLMKTCSSSNKKLPS 1001
Score = 75.9 bits (185), Expect = 2e-11
Identities = 97/490 (19%), Positives = 196/490 (39%), Gaps = 32/490 (6%)
Frame = +1
Query: 11236 ELEVLSSLPIFKTVTGSYTHLQRHGLCIISGDSFLKPYDE-----CCFCYLPDSVECHFL 11400
++++L SLP +K+++G Y + + G C + S E +L + + L
Sbjct: 2653 DIKILKSLPCYKSISGRYVSIGKFGTCYVLTKSIPSAEVEKWTQSSSSAFLEEKIHLKEL 2712
Query: 11401 -QALGVTVLHNHQTLVRFGLAEFESRSQSEREDILIYVYGNWLDLEVDSDVIEALREA-K 11574
+ +G + + + ++ L + E+ S + + LIY+ E S++ E L E +
Sbjct: 2713 YEVIGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLSSAEELSEIKEQLFEKLE 2772
Query: 11575 FVRNSDEFSSELSKSKDLFDPSDTLLVSVFFGERKRFPGERFSS--------------EG 11712
+ + +S L ++K +D + + V E+ P + F
Sbjct: 2773 SLLIIHDANSRLKQAKHFYDRT-VRVFEVMLPEKLFIPNDFFKKLEQLIKPKNHVTFMTS 2831
Query: 11713 WLRILRKAGLRTAAEADVILECAKRVEFLGNERNRSSEEDDFETDLVHSEKDISVELSTL 11892
W+ LR GL+ +L+ AK + N N S E D++ + L
Sbjct: 2832 WVEFLRNIGLKYILSQQQLLQFAKEISVRANTENWSKETLQNTVDIL-LHHIFQERMDLL 2890
Query: 11893 AGSVIEAILLNFAGFYSTAFCNTLGQIACVPAESGFPSLGG-----RKGGKRVLTRYSEA 12057
+G+ ++ + L C + + + G + G +V ++ +
Sbjct: 2891 SGNFLKELSL------IPFLCPERAPAEFIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQC 2944
Query: 12058 VLLRDWPLAWSSVPILSTQRFIPPGFSWTALRLKSPPIFSTVLKHLQVIGRNGGEDTLAH 12237
+L+ L W+S PIL + L VL L V + + +
Sbjct: 2945 DVLQ---LLWTSCPILPEKATPLSIKEQEGSDLGPQEQLEQVLNMLNVNLDPPLDKVINN 3001
Query: 12238 WPNDPNVMTIDVTSCEV-LKYLEIVWDSLTTSDI---LELQKVAFLPAANGTRLVGASSL 12405
N N+ T+D + K L +++ L+ +L+ VAF+ +G +L+ +
Sbjct: 3002 CRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEEV 3061
Query: 12406 FVRLPI--NLSPFAFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSKLQKLCGYRRLNP 12579
+ L + P+ ++LP F + K LG D++S ++LS++ K ++L+P
Sbjct: 3062 VINLEYESDFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDP 3121
Query: 12580 NELRAVMEIL 12609
NE+R V ++
Sbjct: 3122 NEMRTVKRVV 3131
Score = 65.5 bits (158), Expect = 2e-08
Identities = 49/169 (28%), Positives = 75/169 (43%), Gaps = 16/169 (9%)
Frame = +1
Query: 3475 LRQELALAMPKIYSILARLLGSDEMDIVKAVLEGSRWIWVGDGFATLS--EVV--LDGPL 3642
L +E+ K+ + L +++ + + L G ++ V DG+ L EVV L+
Sbjct: 3011 LDEEMVKTRAKVLRSIYEFLSAEKREF-RFQLRGVAFVMVEDGWKLLKPEEVVINLEYES 3069
Query: 3643 QLVPYIRVIPTDLAVFRGLFVELGVREFLTPSDYADVLCRIAVRKGTSPLDPQEIRAAVL 3822
PY+ +P +L F LF LG + ++ Y +VL RI LDP E+R
Sbjct: 3070 DFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKR 3129
Query: 3823 IAQQLAEAQFLDKVTI------------YLPDVSGRLFPSSDLVYNDAP 3933
+ L + D V + YLP GRL SS LV++DAP
Sbjct: 3130 VVSGLFRSLQNDSVKVRSDLENVRDLALYLPSQDGRLVKSSILVFDDAP 3178
Score = 40.4 bits (93), Expect = 0.81
Identities = 31/124 (25%), Positives = 55/124 (44%), Gaps = 4/124 (3%)
Frame = +1
Query: 7726 ESMLQSQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDFVSAD----VLSFDSPVK 7893
E M++++ +L + + LS E + L GV +V + D + V++ +
Sbjct: 3013 EEMVKTRAKVLRSIYEFLSAEKR--EFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYESD 3070
Query: 7894 FTPYLYVVPSELSDFKELLLELGVRLSFDAADYMNTLQHLQNDIKGSQLTDEQINFVLCV 8073
F PYLY +P EL F +L LG Y+ L + + +G QL ++ V V
Sbjct: 3071 FKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRV 3130
Query: 8074 LEAV 8085
+ +
Sbjct: 3131 VSGL 3134
>ref|XP_224256.1| similar to sacsin [Mus musculus] [Rattus norvegicus]
Length = 3830
Score = 258 bits (658), Expect = 2e-66
Identities = 341/1348 (25%), Positives = 557/1348 (41%), Gaps = 118/1348 (8%)
Frame = +1
Query: 1990 ISWHPES-NRDHPSSSWFVLFWQYLDKR-CQSLSLFCDWPILPSTS--------GYLYIA 2139
+ W+P S ++ HPS SW + W+ L + L+LF + P++P T + +
Sbjct: 12 VQWYPLSEDKHHPSISWLKMVWKNLYIHFSEDLTLFDEMPLIPRTPLDADQTCVELIRLR 71
Query: 2140 SPQSKLINAE---KLPAAVRNVLEKIGGKILNN-NIKVEHSDLSSFVSDASYTGVLESIF 2307
P +++ E +LP + ++++K+GG +L + ++H + ++ + +L+ +
Sbjct: 72 VPSVVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSLQHPLVKKYIHSPLPSAILQIM- 130
Query: 2308 DAASSDLDGVQNLIYDLNAQEKDELRSFLLDPKWHIGHQIGDLYLRICKILPIHRIYGET 2487
L + N I L KD LR FL + RI + L I + +
Sbjct: 131 --EKIPLQKLCNQIASLLPTHKDALRKFLASLT-----DTSEKEKRIIQELTIFKRINHS 183
Query: 2488 SAQE-SKYSDLVNPPKHLPPLDVPACL---LGCEFILCCQGSEEDV-LSRYYGIERMRKS 2652
S Q S Y+ L K LD A L L + E + L+ IE+++ +
Sbjct: 184 SDQGISSYTKL----KGCKVLDHTAKLPTELRLSVSVIDSSDEATIRLANMLKIEKLKTT 239
Query: 2653 N---FYRQNVFNRIEVLQPEIRDQVMISILQDLPXXXXXXXXXXXXXXXXXFVPTVNGPL 2823
+ F +++ N + R +M+ IL++L F+ +
Sbjct: 240 SCLKFVLKDIENAFYTQEEVTR--LMLWILENLSSLKNENPSVLDWLMPLKFIHMSQEHV 297
Query: 2824 KRPSVLHDPRNEELYALL--EDSDCFPASGFQGSAILDMLQGLGLKTTVS--PETILESA 2991
S L DP E L L E+ CFP + F IL L+ +GLK S + +++ A
Sbjct: 298 VAASDLFDPDIEVLRDLFYNEEEACFPPAVFTSPDILHSLRQIGLKNEASLKEKDVVQVA 357
Query: 2992 RLVERLMHKDLEKAH---SRGKVLFSFLEVNAVKWLPDQSSEDDGAINRIFSRAATAFRP 3162
+ +E L + + K L L N QSSE A+ +I A RP
Sbjct: 358 KKIEALQVSSCQNQDVLLKKAKTLLLVLNKNHTLL---QSSEGKMALKKIKWVPACKERP 414
Query: 3163 RNLTCNLVKFWSELKMICWCPVLVSAPFQTLPWPVVTSTVAPPKLVRPKTDMWLVSASMR 3342
N +LV + +L +C APP + LV +S+
Sbjct: 415 PNYPGSLV-WKGDLCNLC----------------------APPDMC-DAAHAVLVGSSLP 450
Query: 3343 ILDGECSSTALAYNLGWLSHPGGSAIAAQLLELGKNNEILIDQVLRQ--------ELALA 3498
++ E + +L LG + P SA+ K+ +I++D + +
Sbjct: 451 LV--ESAHVSLEKTLGIFTKPTISAVL-------KHFKIVVDWYTSKTFSDEDYYQFQHI 501
Query: 3499 MPKIYSILARLLGSDEMDIVKAVLEGSRWIWVGDGFATLSEVVLD--GPLQLVPYIRVIP 3672
+ +IY + L S+ D KA+ W+W G F L++ V+ L L PY+ +P
Sbjct: 502 LLEIYGFMHDHL-SEGKDSFKAL--KYPWVWTGKNFCPLAQAVIKPIHDLDLQPYLYNVP 558
Query: 3673 TDLAVFRGLFVELGVREFLTPSDYADVLCRIAVRKGTSPLDPQEIRAAVLIAQQLAEAQF 3852
+A F LF G E LT SD+ ++ + K L +E + + + + +
Sbjct: 559 KTMAKFHQLFKACGSIEELT-SDHISMVIQKVYLKSDQELSEEESKQNLHLMLNIMRWLY 617
Query: 3853 LDK--------VTIYLPDVSGRLF--PSSDLVYNDAPWLTASDNLNSSFSAESTMLLNAK 4002
++ V IY +L P + Y D +D L S E +L
Sbjct: 618 SNQIPASPNTPVPIYHSKNPSKLVMKPIHECCYCDIKVDDLNDLLED--SVEPIIL---- 671
Query: 4003 RTMQKFVHGNISNEVAEKLGVRSLRRVLLAESADSMNFSLSGAAEAFGQHEALTTRLKHI 4182
VH +I + AE L V L L+ + ++M F E GQ E LT R+K+I
Sbjct: 672 ------VHEDIPMKTAEWLKVPCLSTRLI--NPENMGF------EQSGQREPLTVRIKNI 717
Query: 4183 LEMYADGPGILFELVQNAEDAGASEVTFLLD--KTHYGTSSLLSPEMADWQGPALYCFNN 4356
LE Y I EL+QNA+DA A+E +F++D + +LL P MA GPAL+ FNN
Sbjct: 718 LEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWSFNN 777
Query: 4357 SVFTQQDMYAISRIGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFVSGENIVMFDPHANH 4536
S F+ D I+R+G++ K + +G+FGLGFN VYH TDIP +S E ++MFDP+ NH
Sbjct: 778 SEFSDSDFINITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINH 837
Query: 4537 LPG--ISPTHPGLRIKFAGRY-ILDQFPDQFAPFLH-FGCDL------EHTFPGTLFRFP 4686
+ ++PG++I ++ + L +FP+QF PF+ FGC L +++ GTLFR
Sbjct: 838 ISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLAVEAPYSYNGTLFRLS 897
Query: 4687 LRNASVAPRSHIKKETYAPEDVLSLFTSFSGVVSEALIFLRNVKTV-------------- 4824
R A S + Y D+ SL FS +IF ++V ++
Sbjct: 898 FRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVNSMYLKYLKIEETNPTL 957
Query: 4825 ---SIFTKEGAG-------------HEMQLLHRVCKDHNVGQDTEPKPSSQVFSL----- 4941
+I K+ A E L + C N T+ SS + +
Sbjct: 958 AQDTIIIKKKACPSKALNAPVLSVLKEAAKLMKTCSSSNKKLPTDVPKSSCILQITVEEF 1017
Query: 4942 ---------LDENIFAGMNKD-----QLLKK-LSNTVVKDLPYKCQKIVVTEQDSSGCIL 5076
L +F G + D ++ K S +LP K
Sbjct: 1018 HHVFRRIADLQSPLFRGPDDDPATLFEMAKSGQSKKPSDELPQKTVDCTT---------- 1067
Query: 5077 HGWITGECLNAGVSKK-NLNLPEMSHKLIPWASVAVHINSVKNENVEDLAASISNIFGPS 5253
W+ C++ G + K +LN L+P +V V ++ + +
Sbjct: 1068 --WLICTCMDTGEALKFSLNESGRRLGLVPCGAVGVLLHETQEQK--------------- 1110
Query: 5254 TISIQNRRNFGGRAFCFLPLPITTGLPAHINAYFELSSNRRDLWFGNDMAGDGKVRSDWN 5433
+ G FC+LPL I TGLP HIN F ++SNR+++W D K R WN
Sbjct: 1111 ----WTVKPHIGEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIW-----KTDTKGR--WN 1159
Query: 5434 LYLIEEVVVPAYGHLLEKIASELGPCDL----FFSVWP-VTLGTEPWASLVRKLYSFIAN 5598
+ V+V AY L + +L +++VWP + + ++ + + Y IA+
Sbjct: 1160 TTFMRHVIVKAYLQALSVLRDLAISGELIDYTYYAVWPDPDVVHDDFSVICQGFYEDIAH 1219
Query: 5599 -NGLRVLYTKARGGQWISTKQAIYPDFS 5679
G + + G W+S K + D S
Sbjct: 1220 GKGKDLTRVFSDGSMWVSMKNVRFLDDS 1247
Score = 256 bits (653), Expect = 9e-66
Identities = 217/734 (29%), Positives = 329/734 (44%), Gaps = 17/734 (2%)
Frame = +1
Query: 3358 CSSTALAYN--LGWLSHPGGSAIAAQLLELGKNNEILIDQVLRQELALAMPKIYSILARL 3531
C S +LA LG L P + QL ++ K+ +D + Y L
Sbjct: 1521 CGSVSLAVKEFLGLLKKPTVDLVINQLKQVAKS----VDDGITLYQENITNACYKYLHEA 1576
Query: 3532 LGSDEMDIVKAV--LEGSRWIWVGDGFATLSEVVLDGPLQLVPYIRVIPTDLAV-FRGLF 3702
+ +EM + L+ +I V + + +V + PY+ +P FR LF
Sbjct: 1577 ILQNEMAKATIIEKLKPFCFILVENVYVESEKVSFHLNFEAAPYLYQLPNKYKNNFRELF 1636
Query: 3703 VELGVREFLTPSDYADVLCRIAVRKGTSPLDPQEIRAA---------VLIAQQLAEAQFL 3855
+GVR+ T D+A VL I +G + + + LI ++ E
Sbjct: 1637 ESVGVRQSFTVEDFALVLESIDQERGKKQITEENFQLCRRIISEGIWSLIREKRQEFCEK 1696
Query: 3856 DKVTIYLPDVSGRLFPSSDLVYNDAPWLTASDNLNSSFSAESTMLLNAKRTMQKFVHGNI 4035
+ I LPD + L P+ L YND PW+ D+ K+ H +I
Sbjct: 1697 NYGKILLPDTNLLLLPAKSLCYNDCPWIKVKDS------------------SVKYCHADI 1738
Query: 4036 SNEVAEKLGVRSLRRVLLAESADSMNFSLSGAAEAFGQHEALTTRLKHILEMYADGPGIL 4215
EVA KLG R L A ++ F+ G FGQ E LT+R+K IL Y +L
Sbjct: 1739 PREVAVKLGAIPKRHKALERYASNICFTAPGTE--FGQKEKLTSRIKSILNAYPSEKEML 1796
Query: 4216 FELVQNAEDAGASEVTFLLDKTHYGTSSLLSPEMADWQGPALYCFNNSVFTQQDMYAISR 4395
EL+QNA+DA A+E+ F+ D + + + A QGPAL +NN FT+ D+ I
Sbjct: 1797 KELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQN 1856
Query: 4396 IGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFVSGENIV-MFDPHANHLPGISPTHPGLR 4572
+G+ +K P G++G+GFN VYH TD P F+SG +I+ +FDPHA + PG + PG
Sbjct: 1857 LGKGTKEGNPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSVSPGRM 1916
Query: 4573 IKFAGRYILDQFPDQFAPFL--HFGCDLEHTFPGTLFRFPLRNASVAPRSHIKKETYAPE 4746
+ QF D +L HF D T+FRFPLRNA +A S I +
Sbjct: 1917 FRDLDADFRTQFSDVLDLYLGNHFKLD-----NCTMFRFPLRNAEMAQVSEISSVPSSDR 1971
Query: 4747 DVLSLFTSFSGVVSEALIFLRNVKTVSIFTKEGAGHEMQLLHRVCKDHNVGQDTEPKPSS 4926
V +L +E L+FL +++ +SI + A + +L+ V G+ T+
Sbjct: 1972 MVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSV-----KGKITDG---- 2022
Query: 4927 QVFSLLDENIFAGMNKDQLLKKLSNTVVKDLPYKCQKIVVTEQDSSGCILHGWITGECLN 5106
L F D + KK +KD+P + + +DS G L W+ C
Sbjct: 2023 ---DRLKRKQFHASVIDSVTKKRQ---LKDIPVQQITYTMDTEDSEG-NLTTWLI--CNR 2073
Query: 5107 AGVSKKNLNLPEMSHKLIPWASVAVHINSVKNENVEDLAASISNIFGPSTISIQNRRNFG 5286
+G S ++ ++S + I++ +N+++ G I +
Sbjct: 2074 SGFS----SMDKVSKSV---------ISAHRNQDITLFPR------GGVAACITHNYKKP 2114
Query: 5287 GRAFCFLPLPITTGLPAHINAYFELSSNRRDLWFGNDMAGDGKVRSDWNLYLIEEVVVPA 5466
RAFCFLPL + TGLP H+N +F L S RR+LW ++ G VRSDWN L+ ++ PA
Sbjct: 2115 HRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVG---VRSDWNNSLMTALIAPA 2171
Query: 5467 YGHLLEKIASELGP 5508
Y LL ++ P
Sbjct: 2172 YVELLIQLKKRYFP 2185
Score = 234 bits (596), Expect = 4e-59
Identities = 150/430 (34%), Positives = 218/430 (49%), Gaps = 9/430 (2%)
Frame = +1
Query: 22 DFGQKVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLDRRVHGSGSLLSDSL 201
+FGQK LT RI+ +L YP +LKEL+QNADDA AT++ D R H + D
Sbjct: 1771 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKW 1830
Query: 202 AQWQGPSLLAYNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHLTDIPSFVS 381
A QGP+L YN+ FTE+D I +G K G KTG++G+GFNSVYH+TD PSF+S
Sbjct: 1831 APLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPCKTGQYGIGFNSVYHITDCPSFIS 1890
Query: 382 GKYVV-LFDPQGAYLPNISAANPGKRIDYVGSSALSQYKDQFLPYCA--FGCDMRSPFNG 552
G ++ +FDP Y P ++ +PG+ + + +Q+ D Y F D N
Sbjct: 1891 GNDILCIFDPHARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGNHFKLD-----NC 1945
Query: 553 TLFRFPLRNTEQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLFLKCVLSIEMYTWDDG 732
T+FRFPLRN E A S +S + + + D+L +G L+FL + I + D
Sbjct: 1946 TMFRFPLRNAEMAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKA 2005
Query: 733 DSEPKKLYSCSVSSPNNDTV----WHRQAVLRLSKTSISGDREMDAFTLEFLSESEKGNQ 900
LYS + D + +H + ++K D + T +E +GN
Sbjct: 2006 TGGLNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNL 2065
Query: 901 TKRRTDRFYIVQTMASASS--KIGLFAATASKEYDIHLLPWASVAACISDDSSENNILKL 1074
T +++ + SS K+ +A + DI L P VAACI+ +N K
Sbjct: 2066 TT------WLICNRSGFSSMDKVSKSVISAHRNQDITLFPRGGVAACIT-----HNYKKP 2114
Query: 1075 GHAFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKVRSAWNRLLLEDVVAPS 1254
AFCFLPL + TGL VNG+F + S RR +W D VRS WN L+ ++AP+
Sbjct: 2115 HRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRD---DNGVGVRSDWNNSLMTALIAPA 2171
Query: 1255 FARLLLCLRE 1284
+ LL+ L++
Sbjct: 2172 YVELLIQLKK 2181
Score = 204 bits (518), Expect = 4e-50
Identities = 153/576 (26%), Positives = 273/576 (46%), Gaps = 76/576 (13%)
Frame = +1
Query: 4 DSLLLEDFGQKVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLD--RRVHGS 177
+++ E GQ+ LT RI+ +L YP + + KEL+QNADDA AT+ +D R +
Sbjct: 697 ENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMDIR 756
Query: 178 GSLLSDSLAQWQGPSLLAYNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHL 357
+LL +A GP+L ++N++ F++ DF++I+R+G S K G+ K G+FG+GFNSVYH+
Sbjct: 757 ENLLDPGMAACHGPALWSFNNSEFSDSDFINITRLGESLKRGEVDKVGKFGLGFNSVYHI 816
Query: 358 TDIPSFVSGKYVVLFDPQGAYLPN--ISAANPGKRIDY-VGSSALSQYKDQFLPYC-AFG 525
TDIP +S +++++FDP ++ +NPG +I++ L ++ +QF P+ FG
Sbjct: 817 TDIPIIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDVFG 876
Query: 526 CDM----RSP--FNGTLFRFPLRNTEQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLF 687
C + +P +NGTLFR R ++A S +S Y DI + D+ G ++F
Sbjct: 877 CQLPLAVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIF 936
Query: 688 LKCVLSIEMYTWDDGDSEPK--------KLYSCSVSSPNNDTVWHRQAVLRLSKTSISGD 843
+ V S+ + ++ P K +C + N + + +L KT S +
Sbjct: 937 TQSVNSMYLKYLKIEETNPTLAQDTIIIKKKACPSKALNAPVLSVLKEAAKLMKTCSSSN 996
Query: 844 REMDA----------FTLE-------------------------FLSESEKGNQTKRRTD 918
+++ T+E L E K Q+K+ +D
Sbjct: 997 KKLPTDVPKSSCILQITVEEFHHVFRRIADLQSPLFRGPDDDPATLFEMAKSGQSKKPSD 1056
Query: 919 RF---------YIVQTMASASSKIGLFAATASKEYDIHLLPWASVAACISDDSSENNILK 1071
+++ T + + + + L+P +V + + + +K
Sbjct: 1057 ELPQKTVDCTTWLICTCMDTGEALKFSLNESGRR--LGLVPCGAVGVLLHETQEQKWTVK 1114
Query: 1072 --LGHAFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKVRSAWNRLLLEDVV 1245
+G FC+LPL ++TGL + +NG F V+SNR+ IW + R WN + V+
Sbjct: 1115 PHIGEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIWKTDTKGR-------WNTTFMRHVI 1167
Query: 1246 APSFARLLLCLREVLDSRD----SYFSLWPSGS-FEAPWSILVEQIYKNICNA-----PV 1395
++ + L LR++ S + +Y+++WP +S++ + Y++I +
Sbjct: 1168 VKAYLQALSVLRDLAISGELIDYTYYAVWPDPDVVHDDFSVICQGFYEDIAHGKGKDLTR 1227
Query: 1396 LFSDLDGGKWVSPADAYLHDEEFSGSKDLGDALLQL 1503
+FS DG WVS + D+ KD+G A ++
Sbjct: 1228 VFS--DGSMWVSMKNVRFLDDSILQRKDVGSAAFKI 1261
Score = 128 bits (321), Expect = 3e-27
Identities = 171/766 (22%), Positives = 318/766 (41%), Gaps = 51/766 (6%)
Frame = +1
Query: 7420 EFWCQLRSIPWCPICLDPPIEGIPWLESS----NLVASPDRVRPKSQMF------LVSAT 7569
+F + ++IP+ P P + W +S + A+ D + Q +++
Sbjct: 1455 DFAAKYQTIPFLPFLTKPAGFSLEWKGNSFKPETMFAATDLYTAEYQDIVCLLQPILNEN 1514
Query: 7570 MHLLDGECQSSYLHQK--LGWMDCLTIDILCRQLIEISKS-------YKEQKSRSSVNPE 7722
H G C S L K LG + T+D++ QL +++KS Y+E + +
Sbjct: 1515 SHSFRG-CGSVSLAVKEFLGLLKKPTVDLVINQLKQVAKSVDDGITLYQENITNACYKYL 1573
Query: 7723 FESMLQSQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDFVSADVLSFDSPVKFTP 7902
E++LQ+ E+++ LK ++ + + +V ++ +SF + P
Sbjct: 1574 HEAILQN----------EMAKATIIEKLKPFC----FILVENVYVESEKVSFHLNFEAAP 1619
Query: 7903 YLYVVPSEL-SDFKELLLELGVRLSFDAADYMNTLQHLQNDIKGSQLTDEQINFVLC--- 8070
YLY +P++ ++F+EL +GVR SF D+ L+ + + Q+T+E NF LC
Sbjct: 1620 YLYQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQERGKKQITEE--NFQLCRRI 1677
Query: 8071 VLEAVADCFXXXXXXXXXXXXXXXXXAG---FLVPLEDLVYNDAPWVDSSSLSGKRFVHP 8241
+ E + L+P + L YND PW+ S K + H
Sbjct: 1678 ISEGIWSLIREKRQEFCEKNYGKILLPDTNLLLLPAKSLCYNDCPWIKVKDSSVK-YCHA 1736
Query: 8242 SINSDMANRLGIQSLR--CISLVDNDITQDLPCMDF-------TKLKELLSLYASKXXXX 8394
I ++A +LG R + ++I P +F +++K +L+ Y S+
Sbjct: 1737 DIPREVAVKLGAIPKRHKALERYASNICFTAPGTEFGQKEKLTSRIKSILNAYPSEKEML 1796
Query: 8395 XXXXXXADCCKVKKLHIIFDKREHPRKTLLQHNLGEFQGPAIVAILEGVTLTREEICSLQ 8574
AD K ++ +FD R+HP + QGPA+ + T +++ +Q
Sbjct: 1797 KELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPAL-CVYNNQPFTEDDVRGIQ 1855
Query: 8575 LLSQWRIKG---ETLNYGLGLLSCYFMCDLLSIVSGG-YFYMFDPQGATLSASTTQAPAG 8742
L + +G +T YG+G S Y + D S +SG +FDP +T+ +P G
Sbjct: 1856 NLGKGTKEGNPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSVSP-G 1914
Query: 8743 KMFSLIGTNLVERFSDQFNPMLIGQDKAWSLTDSTIIRMPL----STEILKDGFEAGLDR 8910
+MF + + +FSD + L + L + T+ R PL ++ + DR
Sbjct: 1915 RMFRDLDADFRTQFSDVLDLYL---GNHFKLDNCTMFRFPLRNAEMAQVSEISSVPSSDR 1971
Query: 8911 -VKQISDQFLENASRILIFLKSVSQVSFSTWEQGNAQPHQDYTL--HIDSASAIMRNPFA 9081
V+ + D+ + + +L+FL + ++S ++ + Y++ I + R F
Sbjct: 1972 MVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSVKGKITDGDRLKRKQFH 2031
Query: 9082 EKNLKTSKLSRIFGSSNSGVKSRIIEVNLHIGENKLLDRWLVVLSKGSGQ----SQNMAR 9249
+ + R + V+ ++ E L WL+ G S+++
Sbjct: 2032 ASVIDSVTKKRQL--KDIPVQQITYTMDTEDSEGN-LTTWLICNRSGFSSMDKVSKSVIS 2088
Query: 9250 GRKYLAYNLTPVAGVAAHVSRNGRPVDVHAASPIMSPLPLSGSVNLPVTILGCFLIRNNC 9429
+ L P GVAA ++ N + H A LPLS LP + G F + ++
Sbjct: 2089 AHRNQDITLFPRGGVAACITHNYK--KPHRA---FCFLPLSLETGLPFHVNGHFAL-DSA 2142
Query: 9430 GRFLFKNKNERAMSEPQLDAGDILIDAWNKELMSC-VRDSYIEIVV 9564
R L+++ N G + WN LM+ + +Y+E+++
Sbjct: 2143 RRNLWRDDN-----------GVGVRSDWNNSLMTALIAPAYVELLI 2177
Score = 93.6 bits (231), Expect = 8e-17
Identities = 245/1196 (20%), Positives = 449/1196 (37%), Gaps = 121/1196 (10%)
Frame = +1
Query: 6202 ILWTP--GQRGHPTVEWIRVLWSYLKLS-CDDLSVFSKWPILP-----VEDGC--LMQLI 6351
+ W P + HP++ W++++W L + +DL++F + P++P + C L++L
Sbjct: 12 VQWYPLSEDKHHPSISWLKMVWKNLYIHFSEDLTLFDEMPLIPRTPLDADQTCVELIRLR 71
Query: 6352 LNSNVIRDDGWS----ENMSSLLLKCGCRFLNR-ELPVEHPQLETFVQPPTATGILNALL 6516
+ S VI DD E ++ ++ K G L R + ++HP ++ ++ P + IL +
Sbjct: 72 VPSVVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSLQHPLVKKYIHSPLPSAILQIME 131
Query: 6517 AISGGHENIKGIFLNVSEGELHELRNFILQSKWFSGGHMNEVHFETIKHLPIFE--SYRS 6690
I + + ++ LR F+ S +E I+ L IF+ ++ S
Sbjct: 132 KIP--LQKLCNQIASLLPTHKDALRKFLA-----SLTDTSEKEKRIIQELTIFKRINHSS 184
Query: 6691 RKLVSLNCPVKWLKPDGIREDL---LDDDFVRLDSERERTI-FKRYLQIKEPSKMEFYKA 6858
+ +S +K K L L +DS E TI L+I++ K
Sbjct: 185 DQGISSYTKLKGCKVLDHTAKLPTELRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLKF 244
Query: 6859 CVLNRMSEFLSQQEA---LLAILHDLNDLVVADVSLQCAISTTPFVLAANGLWQQPSRLY 7029
+ + + F +Q+E +L IL +L+ L + S+ + F+ + S L+
Sbjct: 245 VLKDIENAFYTQEEVTRLMLWILENLSSLKNENPSVLDWLMPLKFIHMSQEHVVAASDLF 304
Query: 7030 DPRVPALQELLH--KEVYFPSEKFSDSKILDALVGLGLR--TTLDCSTYLDAARSVSMLH 7197
DP + L++L + +E FP F+ IL +L +GL+ +L + A+ + L
Sbjct: 305 DPDIEVLRDLFYNEEEACFPPAVFTSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEAL- 363
Query: 7198 DLGDLEASRYGRRLLFHIKTLSIKLSSKTGEANHDESQNIMSITSEDSFDGXXXXXXXXX 7377
+ + + LL KTL + L+ NH
Sbjct: 364 ---QVSSCQNQDVLLKKAKTLLLVLNK-----NH-------------------------- 389
Query: 7378 XXXLGSLLTQQSEDEFWCQLRSIPWCPICLDPPIE---GIPWL-ESSNLVASPDRVRPKS 7545
L Q SE + L+ I W P C + P + W + NL A PD + +
Sbjct: 390 ------TLLQSSEGKM--ALKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPD-MCDAA 440
Query: 7546 QMFLVSATMHLLDGECQSSYLHQKLGWMDCLTIDILCRQLIEISKSYKEQKSRSSVNPEF 7725
LV +++ L++ S L + LG TI + + + Y + +F
Sbjct: 441 HAVLVGSSLPLVESAHVS--LEKTLGIFTKPTISAVLKHFKIVVDWYTSKTFSDEDYYQF 498
Query: 7726 ESMLQSQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDF--VSADVLSFDSPVKFT 7899
+ +L ++ L E ++ F ALK PWVW G +F ++ V+ +
Sbjct: 499 QHILLEIYGFMHDHLSE--GKDSFKALK-----YPWVWTGKNFCPLAQAVIKPIHDLDLQ 551
Query: 7900 PYLYVVPSELSDFKELLLELG--VRLSFDAADYMNTLQHLQNDIKGSQLTDEQ-INFVLC 8070
PYLY VP ++ F +L G L+ D + +L++D + S+ +Q ++ +L
Sbjct: 552 PYLYNVPKTMAKFHQLFKACGSIEELTSDHISMVIQKVYLKSDQELSEEESKQNLHLMLN 611
Query: 8071 VLE-AVADCFXXXXXXXXXXXXXXXXXAGFLVPLEDLVYNDAPWVD-----SSSLSGKRF 8232
++ ++ + P+ + Y D D S+
Sbjct: 612 IMRWLYSNQIPASPNTPVPIYHSKNPSKLVMKPIHECCYCDIKVDDLNDLLEDSVEPIIL 671
Query: 8233 VHPSINSDMANRLGIQ--SLRCISLVDNDITQDLPCMDFT-KLKELLSLYASKXXXXXXX 8403
VH I A L + S R I+ + Q T ++K +L Y S
Sbjct: 672 VHEDIPMKTAEWLKVPCLSTRLINPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKEL 731
Query: 8404 XXXADCCKVKKLHIIFDKREHP--RKTLLQHNLGEFQGPAIVAILEGVTLTREEICSLQL 8577
AD + + D R + R+ LL + GPA+ + + + ++
Sbjct: 732 LQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWS-FNNSEFSDSDFINITR 790
Query: 8578 LSQWRIKGE---TLNYGLGLLSCYFMCDLLSIVSGGYFYMFDPQGATLS--ASTTQAPAG 8742
L + +GE +GLG S Y + D+ I+S + MFDP +S P
Sbjct: 791 LGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDRSNPGI 850
Query: 8743 KMFSLIGTNLVERFSDQFNPML--------IGQDKAWSLTDSTIIRMPLSTEILKDGFEA 8898
K+ + +F +QF P + + + +S + T+ R+ T+ E
Sbjct: 851 KINWSKQQKRLRKFPNQFKPFIDVFGCQLPLAVEAPYSY-NGTLFRLSFRTQQEAKVSEV 909
Query: 8899 -----GLDRVKQISDQFLENASRILIFLKSVSQ--VSFSTWEQGNAQPHQDYTLHIDSA- 9054
+ + D+F R++IF +SV+ + + E+ N QD + A
Sbjct: 910 SSTCYNTADIYSLVDEFSLCGHRLIIFTQSVNSMYLKYLKIEETNPTLAQDTIIIKKKAC 969
Query: 9055 -SAIMRNPFAEKNLKTSKLSRIFGSSNSGV------KSRIIEVNL----HI--------- 9174
S + P + +KL + SSN + S I+++ + H+
Sbjct: 970 PSKALNAPVLSVLKEAAKLMKTCSSSNKKLPTDVPKSSCILQITVEEFHHVFRRIADLQS 1029
Query: 9175 -------------------GENKL-----------LDRWLVVLSKGSGQSQNMARGRKYL 9264
G++K WL+ +G++ +
Sbjct: 1030 PLFRGPDDDPATLFEMAKSGQSKKPSDELPQKTVDCTTWLICTCMDTGEALKFSLNESGR 1089
Query: 9265 AYNLTP--VAGVAAHVSRNGRPVDVHAASPIMSPLPLSGSVNLPVTILGCFLIRNN 9426
L P GV H ++ + + LPL LP+ I GCF + +N
Sbjct: 1090 RLGLVPCGAVGVLLHETQEQKWTVKPHIGEVFCYLPLRIKTGLPIHINGCFAVTSN 1145
Score = 78.2 bits (191), Expect = 4e-12
Identities = 103/491 (20%), Positives = 198/491 (39%), Gaps = 33/491 (6%)
Frame = +1
Query: 11236 ELEVLSSLPIFKTVTGSYTHLQRHGLCIISGDSFLKPYDE-----CCFCYLPDSVECHFL 11400
+L++L SLP +K+++G Y + + G C + S E +L + V L
Sbjct: 2653 DLKILKSLPCYKSISGRYMSIAKFGTCYVLTKSIPSAEVEKWTQSSSSAFLEEKVHLKEL 2712
Query: 11401 -QALGVTVLHNHQTLVRFGLAEFESRSQSEREDILIYVYGNWLDLEVDSDVIEALREA-K 11574
+ LG + + + ++ L + E+ S + + LIY+ +E S+ E L E +
Sbjct: 2713 YEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLASIEELSETKEQLFEKLE 2772
Query: 11575 FVRNSDEFSSELSKSKDLFDPSDTLLVSVFFGERKRFPGERFSS--------------EG 11712
+ + ++ L ++K +D + + V E+ P E F
Sbjct: 2773 SLLIIHDANNRLKQAKHFYDRT-VRVFEVMLPEKLFIPKEFFKKLEQVIKPKNQVVFMTS 2831
Query: 11713 WLRILRKAGLRTAAEADVILECAKRVEFLGNERNRSSEEDDFETD-LVHSEKDISVELST 11889
W+ LR GL+ +L+ AK + N N S E D L+H +L
Sbjct: 2832 WVEFLRNIGLKHVLSQQQLLQFAKEISVRANTENWSKETLQNTVDILLHHIFQERTDL-- 2889
Query: 11890 LAGSVIEAILLNFAGFYSTAFCNTLGQIACVPAESGFPSLGG-----RKGGKRVLTRYSE 12054
L+G+ ++ + L C + + + G + G +V ++ +
Sbjct: 2890 LSGNFLKELSL------IPFLCPERAPAEYIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQ 2943
Query: 12055 AVLLRDWPLAWSSVPILSTQRFIPPGFSWTALRLKSPPIFSTVLKHLQVIGRNGGEDTLA 12234
+L+ L W+S PIL + L VL L V + +
Sbjct: 2944 CDVLQ---LLWTSCPILPEKATPLSIKEQEGSSLAPQEQLEQVLNMLNVNLDPPLDKVIN 3000
Query: 12235 HWPNDPNVMTIDVTSCEV-LKYLEIVWDSLTTSDI---LELQKVAFLPAANGTRLVGASS 12402
+ N N+ T+D + K L +++ L+ +L+ VAF+ +G +L+
Sbjct: 3001 NCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEE 3060
Query: 12403 LFVRLPI--NLSPFAFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSKLQKLCGYRRLN 12576
+ + L + P+ ++LP F + K LG D++S ++LS++ K ++L+
Sbjct: 3061 VVINLEYEADFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLD 3120
Query: 12577 PNELRAVMEIL 12609
PNE+R V ++
Sbjct: 3121 PNEMRTVKRVV 3131
Score = 66.2 bits (160), Expect = 1e-08
Identities = 49/169 (28%), Positives = 76/169 (43%), Gaps = 16/169 (9%)
Frame = +1
Query: 3475 LRQELALAMPKIYSILARLLGSDEMDIVKAVLEGSRWIWVGDGFATLS--EVV--LDGPL 3642
L +E+ K+ + L +++ + + L G ++ V DG+ L EVV L+
Sbjct: 3011 LDEEMVKTRAKVLRSIYEFLSAEKREF-RFQLRGVAFVMVEDGWKLLKPEEVVINLEYEA 3069
Query: 3643 QLVPYIRVIPTDLAVFRGLFVELGVREFLTPSDYADVLCRIAVRKGTSPLDPQEIRAAVL 3822
PY+ +P +L F LF LG + ++ Y +VL RI LDP E+R
Sbjct: 3070 DFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKR 3129
Query: 3823 IAQQLAEAQFLDKVTI------------YLPDVSGRLFPSSDLVYNDAP 3933
+ L ++ D V + YLP GRL SS LV++DAP
Sbjct: 3130 VVSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGRLVKSSILVFDDAP 3178
Score = 46.6 bits (109), Expect = 0.011
Identities = 68/263 (25%), Positives = 117/263 (43%), Gaps = 16/263 (6%)
Frame = +1
Query: 11059 KCLPSPSVSLGQAIASKLAEGKRAGYIADIASFPTFGRDELFTLLANDFSSSGSSYQAYE 11238
K + SP S I K+ K IA + PT +D L LA+ +S E
Sbjct: 116 KYIHSPLPSAILQIMEKIPLQKLCNQIASL--LPTH-KDALRKFLASLTDTSEK-----E 167
Query: 11239 LEVLSSLPIFKTVT-------GSYTHLQRHGLCIISGDSFLKPYDECCFCYLPDSVECHF 11397
++ L IFK + SYT L+ C + + P + + DS +
Sbjct: 168 KRIIQELTIFKRINHSSDQGISSYTKLKG---CKVLDHTAKLPTELRLSVSVIDSSDEAT 224
Query: 11398 LQALGVTVLHNHQTL--VRFGLAEFESR--SQSEREDILIYVYGNWLDLEVDS-DVIEAL 11562
++ + + +T ++F L + E+ +Q E +++++ N L+ ++ V++ L
Sbjct: 225 IRLANMLKIEKLKTTSCLKFVLKDIENAFYTQEEVTRLMLWILENLSSLKNENPSVLDWL 284
Query: 11563 REAKFVRNSDEFSSELSKSKDLFDPSDTLLVSVFFGERKR-FPGERFSSEGWLRILRKAG 11739
KF+ S E + + DLFDP +L +F+ E + FP F+S L LR+ G
Sbjct: 285 MPLKFIHMSQE---HVVAASDLFDPDIEVLRDLFYNEEEACFPPAVFTSPDILHSLRQIG 341
Query: 11740 LRTAA---EADVILECAKRVEFL 11799
L+ A E DV+ + AK++E L
Sbjct: 342 LKNEASLKEKDVV-QVAKKIEAL 363
Score = 42.0 bits (97), Expect = 0.28
Identities = 40/168 (23%), Positives = 66/168 (38%), Gaps = 11/168 (6%)
Frame = +1
Query: 7726 ESMLQSQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDFVSAD----VLSFDSPVK 7893
E M++++ +L + + LS E + L GV +V + D + V++ +
Sbjct: 3013 EEMVKTRAKVLRSIYEFLSAEKR--EFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYEAD 3070
Query: 7894 FTPYLYVVPSELSDFKELLLELGVRLSFDAADYMNTLQHLQNDIKGSQLTDEQINFVLCV 8073
F PYLY +P EL F +L LG Y+ L + + +G QL ++ V V
Sbjct: 3071 FKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRV 3130
Query: 8074 LEAVADCFXXXXXXXXXXXXXXXXXA-------GFLVPLEDLVYNDAP 8196
+ + A G LV LV++DAP
Sbjct: 3131 VSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGRLVKSSILVFDDAP 3178
>ref|NP_056603.1| sacsin [Mus musculus]|gi|13124519|sp|Q9JLC8|SACS_MOUSE
Sacsin|gi|6907044|gb|AAF31263.1| sacsin [Mus musculus]
Length = 3830
Score = 256 bits (655), Expect = 6e-66
Identities = 269/989 (27%), Positives = 413/989 (41%), Gaps = 35/989 (3%)
Frame = +1
Query: 2647 KSNFYRQNVFNRIEVLQPEIRDQVMISILQDLPXXXXXXXXXXXXXXXXXFVP-TVNG-P 2820
+ F+ + F I+ ++ E+RD +M +L + VP ++ G P
Sbjct: 1303 EKQFFSEVFFPNIQEIEAELRDPLMNFVLNE------KLDEFSGILRVTPCVPCSLEGHP 1356
Query: 2821 LKRPSVLHDPRNEELYALLEDSDCFPASGFQ---GSAILDMLQGLGL-KTTVSPETILES 2988
L PS L P FP Q IL L LG+ K + + +LE
Sbjct: 1357 LVLPSRLIHPEGRVAKLFDTKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLER 1416
Query: 2989 ARLVERLMHKDLEKAHSRGKVLFSFLEVNAVKWLPDQSSEDDGAINRIFSRAATAFRPRN 3168
A V + D A R +L S ++ + D ++D
Sbjct: 1417 AESVAEINKSDHAAACLRSSILLSLIDEKLK--IKDPRAKD------------------- 1455
Query: 3169 LTCNLVKFWSELKMICWCPVLVSAPFQTLPWPVVTSTVAPPKLVRPKTDMW------LVS 3330
F ++ + I + P L +L W P+ + TD++ +V
Sbjct: 1456 -------FAAKYQTIPFLPFLTKPAGFSLEWK---GNSFKPETMFAATDIYTAEYQDIVC 1505
Query: 3331 ASMRILDGE------CSSTALAYN--LGWLSHPGGSAIAAQLLELGKNNEILIDQVLRQE 3486
IL+ C S +LA LG L P + QL ++ K+ +D +
Sbjct: 1506 LLQPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKQVAKS----VDDGITLY 1561
Query: 3487 LALAMPKIYSILARLLGSDEMDIVKAV--LEGSRWIWVGDGFATLSEVVLDGPLQLVPYI 3660
Y L + +EM + L+ +I V + + +V + PY+
Sbjct: 1562 QENITNACYKYLHEAVLQNEMAKATIIEKLKPFCFILVENVYVESEKVSFHLNFEAAPYL 1621
Query: 3661 RVIPTDLAV-FRGLFVELGVREFLTPSDYADVLCRIAVRKGTSPLDPQEIRAA------- 3816
+P FR LF +GVR+ T D+A VL I +G + + +
Sbjct: 1622 YQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQERGKKQITEENFQLCRRIISEG 1681
Query: 3817 --VLIAQQLAEAQFLDKVTIYLPDVSGRLFPSSDLVYNDAPWLTASDNLNSSFSAESTML 3990
LI ++ E + I LPD + L P+ L YND PW+ D ST+
Sbjct: 1682 IWSLIREKRQEFCEKNYGKILLPDTNLLLLPAKSLCYNDCPWIKVKD---------STV- 1731
Query: 3991 LNAKRTMQKFVHGNISNEVAEKLGVRSLRRVLLAESADSMNFSLSGAAEAFGQHEALTTR 4170
K+ H +I EVA KLG R L A ++ F+ G FGQ E LT+R
Sbjct: 1732 --------KYCHADIPREVAVKLGAIPKRHKALERYASNICFTALGTE--FGQKEKLTSR 1781
Query: 4171 LKHILEMYADGPGILFELVQNAEDAGASEVTFLLDKTHYGTSSLLSPEMADWQGPALYCF 4350
+K IL Y +L EL+QNA+DA A+E+ F+ D + + + A QGPAL +
Sbjct: 1782 IKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVY 1841
Query: 4351 NNSVFTQQDMYAISRIGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFVSGENIV-MFDPH 4527
NN FT+ D+ I +G+ +K P G +G+GFN VYH TD P F+SG +I+ +FDPH
Sbjct: 1842 NNQPFTEDDVRGIQNLGKGTKEGNPCKTGHYGIGFNSVYHITDCPSFISGNDILGIFDPH 1901
Query: 4528 ANHLPGISPTHPGLRIKFAGRYILDQFPDQFAPFL--HFGCDLEHTFPGTLFRFPLRNAS 4701
A + PG + PG + QF D +L HF D T+FRFPLRNA
Sbjct: 1902 ARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGNHFKLD-----NCTMFRFPLRNAE 1956
Query: 4702 VAPRSHIKKETYAPEDVLSLFTSFSGVVSEALIFLRNVKTVSIFTKEGAGHEMQLLHRVC 4881
+A S I + V +L +E L+FL +++ +SI + A + +L+ V
Sbjct: 1957 MAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSV- 2015
Query: 4882 KDHNVGQDTEPKPSSQVFSLLDENIFAGMNKDQLLKKLSNTVVKDLPYKCQKIVVTEQDS 5061
G+ T+ L F D + KK +KD+P + + +DS
Sbjct: 2016 ----KGKITDG-------DRLKRKQFHASVIDSVTKKRQ---LKDIPVQQITYTMDTEDS 2061
Query: 5062 SGCILHGWITGECLNAGVSKKNLNLPEMSHKLIPWASVAVHINSVKNENVEDLAASISNI 5241
G L W+ C +G S ++ ++S + I++ KN+++
Sbjct: 2062 EG-NLTTWLI--CNRSGFS----SMEKVSKSV---------ISAHKNQDITLFPR----- 2100
Query: 5242 FGPSTISIQNRRNFGGRAFCFLPLPITTGLPAHINAYFELSSNRRDLWFGNDMAGDGKVR 5421
G I + RAFCFLPL + TGLP H+N +F L S RR+LW ++ G VR
Sbjct: 2101 -GGVAACITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVG---VR 2156
Query: 5422 SDWNLYLIEEVVVPAYGHLLEKIASELGP 5508
SDWN L+ ++ PAY LL ++ P
Sbjct: 2157 SDWNNSLMTALIAPAYVELLIQLKKRYFP 2185
Score = 256 bits (653), Expect = 9e-66
Identities = 337/1340 (25%), Positives = 549/1340 (40%), Gaps = 110/1340 (8%)
Frame = +1
Query: 1990 ISWHPES-NRDHPSSSWFVLFWQYLDKR-CQSLSLFCDWPILPSTS--------GYLYIA 2139
+ W+P S ++ HPS SW + W+ L + L+LF + P++P T + +
Sbjct: 12 VQWYPFSEDKRHPSLSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTLLNEDQTCVELIRLR 71
Query: 2140 SPQSKLINAE---KLPAAVRNVLEKIGGKILNN-NIKVEHSDLSSFVSDASYTGVLESIF 2307
P +++ E +LP + ++++K+GG +L + ++H + ++ + +L+ +
Sbjct: 72 IPSVVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSIQHPLVKKYIHSPLPSAILQIM- 130
Query: 2308 DAASSDLDGVQNLIYDLNAQEKDELRSFLLDPKWHIGHQIGDLYLRICKILPIHRIYGET 2487
L + N I L KD LR FL + RI + L I + +
Sbjct: 131 --EKIPLQKLCNQIASLLPTHKDALRKFLASLT-----DTSEKEKRIIQELTIFKRINHS 183
Query: 2488 SAQE-SKYSDLVNPPKHLPPLDVPACLLGCEFILCCQGSEEDVLSRYYGIERMRKSN--- 2655
S Q S Y+ L +P L ++ L+ IE+++ ++
Sbjct: 184 SDQGISSYTKLKGCKVLDHTAKLPTDLRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLK 243
Query: 2656 FYRQNVFNRIEVLQPEIRDQVMISILQDLPXXXXXXXXXXXXXXXXXFVPTVNGPLKRPS 2835
F +++ N Q E+ Q+M+ IL++L F+ G +
Sbjct: 244 FVLKDIGNAFYT-QEEVT-QLMLWILENLSSLKNENSNVLDWLMPLKFIHMSQGHVVAAG 301
Query: 2836 VLHDPRNEELYALL--EDSDCFPASGFQGSAILDMLQGLGLK--TTVSPETILESARLVE 3003
L DP E L L E+ CFP + F IL L+ +GLK +++ + +++ AR +E
Sbjct: 302 DLFDPDIEVLRDLFYNEEEACFPPTIFTSPDILHSLRQIGLKNESSLKEKDVVQVARKIE 361
Query: 3004 RLMHKDLEKAH---SRGKVLFSFLEVNAVKWLPDQSSEDDGAINRIFSRAATAFRPRNLT 3174
L + + K L L N QSSE A+ +I A RP N
Sbjct: 362 ALQVSSCQNQDVLMKKAKTLLLVLNKNQTLL---QSSEGKMALKKIKWVPACKERPPNYP 418
Query: 3175 CNLVKFWS-ELKMICWCPVLVSAPFQTLPWPVVTSTVAPPKLVRPKTDMWLVSASMRILD 3351
+LV W +L +C P + A L V +S+ ++
Sbjct: 419 GSLV--WKGDLCNLCAPPDMCDAAHAVL-----------------------VGSSLPLV- 452
Query: 3352 GECSSTALAYNLGWLSHPGGSAIAAQLLELGK--NNEILIDQVLRQELALAMPKIYSILA 3525
E L L + P +A+ + ++ D+ Q + + +IY +
Sbjct: 453 -ESVHVNLEQALSIFTKPTINAVLKHFKTVVDWYTSKTFSDEDYYQFQHILL-EIYGFMH 510
Query: 3526 RLLGSDEMDIVKAVLEGSRWIWVGDGFATLSEVVLDGP--LQLVPYIRVIPTDLAVFRGL 3699
L S+ D KA+ W+W G F L++ V+ L L PY+ +P +A F L
Sbjct: 511 DHL-SEGKDSFKALK--FPWVWTGKNFCPLAQAVIKPTHDLDLQPYLYNVPKTMAKFHQL 567
Query: 3700 FVELGVREFLTPSDYADVLCRIAVRKGTSPLDPQEIRAAVLIAQQLAEAQFLDK------ 3861
F G E LT SD+ ++ + K L +E + + + + + ++
Sbjct: 568 FKACGSIEELT-SDHISMVIQKVYLKSDQELSEEESKQNLHLMLNIMRWLYSNQIPASPN 626
Query: 3862 --VTIYLPDVSGRLF--PSSDLVYNDAPWLTASDNLNSSFSAESTMLLNAKRTMQKFVHG 4029
V IY +L P + Y D +D L S E +L VH
Sbjct: 627 TPVPIYHSRNPSKLVMKPIHECCYCDIKVDDLNDLLEDS--VEPIIL----------VHE 674
Query: 4030 NISNEVAEKLGVRSLRRVLLAESADSMNFSLSGAAEAFGQHEALTTRLKHILEMYADGPG 4209
+I + AE L V L L+ + ++M F SG Q E LT R+K+ILE Y
Sbjct: 675 DIPMKTAEWLKVPCLSTRLI--NPENMGFEQSG------QREPLTVRIKNILEEYPSVSD 726
Query: 4210 ILFELVQNAEDAGASEVTFLLDKTHYGT--SSLLSPEMADWQGPALYCFNNSVFTQQDMY 4383
I EL+QNA+DA A+E +F++D +LL P MA GPAL+ FNNS F+ D
Sbjct: 727 IFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWSFNNSEFSDSDFL 786
Query: 4384 AISRIGQASKLEKPFAIGRFGLGFNCVYHFTDIPGFVSGENIVMFDPHANHLPG--ISPT 4557
I+R+G++ K + +G+FGLGFN VYH TDIP +S E ++MFDP+ NH+ +
Sbjct: 787 NITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDRS 846
Query: 4558 HPGLRIKFAGRY-ILDQFPDQFAPFLH-FGCDL------EHTFPGTLFRFPLRNASVAPR 4713
+PG++I ++ + L +FP+QF PF+ FGC L +++ GTLFR R A
Sbjct: 847 NPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLAVEAPYSYNGTLFRLSFRTQQEAKV 906
Query: 4714 SHIKKETYAPEDVLSLFTSFSGVVSEALIFLRNVKTV-----------------SIFTKE 4842
S + Y D+ SL FS +IF ++V ++ +I K+
Sbjct: 907 SEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVNSMYLKYLKIEETNPSLAQDTIIIKK 966
Query: 4843 -------------GAGHEMQLLHRVCKDHNVGQDTEPKPSSQVFSL-------------- 4941
E L + C N T+ SS + +
Sbjct: 967 KVCPSKALNAPVLSVLKEAAKLMKTCSSSNKKLPTDVPKSSCILQITVEEFHHVFRRIAD 1026
Query: 4942 LDENIFAGMNKD-----QLLKK-LSNTVVKDLPYKCQKIVVTEQDSSGCILHGWITGECL 5103
L +F G + D ++ K S +LP K W+ C+
Sbjct: 1027 LQSPLFRGPDDDPATLFEMAKSGQSKKPSDELPQKTVDCTT------------WLICTCM 1074
Query: 5104 NAGVSKK-NLNLPEMSHKLIPWASVAVHINSVKNENVEDLAASISNIFGPSTISIQNRRN 5280
+ G + K +LN L+P +V V ++ + + +
Sbjct: 1075 DTGEALKFSLNESGRRLGLVPCGAVGVLLHETQEQK-------------------WTVKP 1115
Query: 5281 FGGRAFCFLPLPITTGLPAHINAYFELSSNRRDLWFGNDMAGDGKVRSDWNLYLIEEVVV 5460
G FC+LPL I TGLP HIN F ++SNR+++W D K R WN + V+V
Sbjct: 1116 HIGEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIW-----KTDTKGR--WNTTFMRHVIV 1168
Query: 5461 PAYGHLLE-----KIASELGPCDLFFSVWP-VTLGTEPWASLVRKLYSFIAN-NGLRVLY 5619
AY L I EL +++VWP L + ++ + + Y IA+ G +
Sbjct: 1169 KAYLQALSVLRDLAIGGELTDY-TYYAVWPDPDLVHDDFSVICKGFYEDIAHGKGKELTR 1227
Query: 5620 TKARGGQWISTKQAIYPDFS 5679
+ G W+S K + D S
Sbjct: 1228 VFSDGSMWVSMKNVRFLDDS 1247
Score = 234 bits (598), Expect = 2e-59
Identities = 151/430 (35%), Positives = 217/430 (50%), Gaps = 9/430 (2%)
Frame = +1
Query: 22 DFGQKVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLDRRVHGSGSLLSDSL 201
+FGQK LT RI+ +L YP +LKEL+QNADDA AT++ D R H + D
Sbjct: 1771 EFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKW 1830
Query: 202 AQWQGPSLLAYNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHLTDIPSFVS 381
A QGP+L YN+ FTE+D I +G K G KTG +G+GFNSVYH+TD PSF+S
Sbjct: 1831 APLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPCKTGHYGIGFNSVYHITDCPSFIS 1890
Query: 382 GKYVV-LFDPQGAYLPNISAANPGKRIDYVGSSALSQYKDQFLPYCA--FGCDMRSPFNG 552
G ++ +FDP Y P ++ +PG+ + + +Q+ D Y F D N
Sbjct: 1891 GNDILGIFDPHARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGNHFKLD-----NC 1945
Query: 553 TLFRFPLRNTEQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLFLKCVLSIEMYTWDDG 732
T+FRFPLRN E A S +S + + + D+L +G L+FL + I + D
Sbjct: 1946 TMFRFPLRNAEMAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKA 2005
Query: 733 DSEPKKLYSCSVSSPNNDTV----WHRQAVLRLSKTSISGDREMDAFTLEFLSESEKGNQ 900
LYS + D + +H + ++K D + T +E +GN
Sbjct: 2006 TGGLNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNL 2065
Query: 901 TKRRTDRFYIVQTMASASS--KIGLFAATASKEYDIHLLPWASVAACISDDSSENNILKL 1074
T +++ + SS K+ +A K DI L P VAACI+ +N K
Sbjct: 2066 TT------WLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACIT-----HNYKKP 2114
Query: 1075 GHAFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKVRSAWNRLLLEDVVAPS 1254
AFCFLPL + TGL VNG+F + S RR +W D VRS WN L+ ++AP+
Sbjct: 2115 HRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRD---DNGVGVRSDWNNSLMTALIAPA 2171
Query: 1255 FARLLLCLRE 1284
+ LL+ L++
Sbjct: 2172 YVELLIQLKK 2181
Score = 201 bits (510), Expect = 4e-49
Identities = 152/576 (26%), Positives = 271/576 (46%), Gaps = 76/576 (13%)
Frame = +1
Query: 4 DSLLLEDFGQKVDLTRRIREVLLNYPEGTTVLKELIQNADDAGATKVRLCLD--RRVHGS 177
+++ E GQ+ LT RI+ +L YP + + KEL+QNADDA AT+ +D R +
Sbjct: 697 ENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMDIR 756
Query: 178 GSLLSDSLAQWQGPSLLAYNDAVFTEEDFVSISRIGGSGKHGQAWKTGRFGVGFNSVYHL 357
+LL +A GP+L ++N++ F++ DF++I+R+G S K G+ K G+FG+GFNSVYH+
Sbjct: 757 ENLLDPGMAACHGPALWSFNNSEFSDSDFLNITRLGESLKRGEVDKVGKFGLGFNSVYHI 816
Query: 358 TDIPSFVSGKYVVLFDPQGAYLPN--ISAANPGKRIDY-VGSSALSQYKDQFLPYC-AFG 525
TDIP +S +++++FDP ++ +NPG +I++ L ++ +QF P+ FG
Sbjct: 817 TDIPIIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDVFG 876
Query: 526 CDM----RSP--FNGTLFRFPLRNTEQAASSRLSRQAYFEDDISLMFDQLFEEGVFSLLF 687
C + +P +NGTLFR R ++A S +S Y DI + D+ G ++F
Sbjct: 877 CQLPLAVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIF 936
Query: 688 LKCVLSIEMYTWDDGDSEPK--------KLYSCSVSSPNNDTVWHRQAVLRLSKTSISGD 843
+ V S+ + ++ P K C + N + + +L KT S +
Sbjct: 937 TQSVNSMYLKYLKIEETNPSLAQDTIIIKKKVCPSKALNAPVLSVLKEAAKLMKTCSSSN 996
Query: 844 REMDA----------FTLE-------------------------FLSESEKGNQTKRRTD 918
+++ T+E L E K Q+K+ +D
Sbjct: 997 KKLPTDVPKSSCILQITVEEFHHVFRRIADLQSPLFRGPDDDPATLFEMAKSGQSKKPSD 1056
Query: 919 RF---------YIVQTMASASSKIGLFAATASKEYDIHLLPWASVAACISDDSSENNILK 1071
+++ T + + + + L+P +V + + + +K
Sbjct: 1057 ELPQKTVDCTTWLICTCMDTGEALKFSLNESGRR--LGLVPCGAVGVLLHETQEQKWTVK 1114
Query: 1072 --LGHAFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKVRSAWNRLLLEDVV 1245
+G FC+LPL ++TGL + +NG F V+SNR+ IW + R WN + V+
Sbjct: 1115 PHIGEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIWKTDTKGR-------WNTTFMRHVI 1167
Query: 1246 APSFARLLLCLREVLDSRD----SYFSLWPSGSF-EAPWSILVEQIYKNICNA-----PV 1395
++ + L LR++ + +Y+++WP +S++ + Y++I +
Sbjct: 1168 VKAYLQALSVLRDLAIGGELTDYTYYAVWPDPDLVHDDFSVICKGFYEDIAHGKGKELTR 1227
Query: 1396 LFSDLDGGKWVSPADAYLHDEEFSGSKDLGDALLQL 1503
+FS DG WVS + D+ KD+G A ++
Sbjct: 1228 VFS--DGSMWVSMKNVRFLDDSILQRKDVGSAAFKI 1261
Score = 126 bits (316), Expect = 1e-26
Identities = 170/768 (22%), Positives = 317/768 (41%), Gaps = 53/768 (6%)
Frame = +1
Query: 7420 EFWCQLRSIPWCPICLDPPIEGIPWLESS----NLVASPDRVRPKSQMF------LVSAT 7569
+F + ++IP+ P P + W +S + A+ D + Q +++
Sbjct: 1455 DFAAKYQTIPFLPFLTKPAGFSLEWKGNSFKPETMFAATDIYTAEYQDIVCLLQPILNEN 1514
Query: 7570 MHLLDGECQSSYLHQK--LGWMDCLTIDILCRQLIEISKS-------YKEQKSRSSVNPE 7722
H G C S L K LG + T+D++ QL +++KS Y+E + +
Sbjct: 1515 SHSFRG-CGSVSLAVKEFLGLLKKPTVDLVINQLKQVAKSVDDGITLYQENITNACYKYL 1573
Query: 7723 FESMLQSQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDFVSADVLSFDSPVKFTP 7902
E++LQ+ E+++ LK ++ + + +V ++ +SF + P
Sbjct: 1574 HEAVLQN----------EMAKATIIEKLKPFC----FILVENVYVESEKVSFHLNFEAAP 1619
Query: 7903 YLYVVPSEL-SDFKELLLELGVRLSFDAADYMNTLQHLQNDIKGSQLTDEQINFVLC--- 8070
YLY +P++ ++F+EL +GVR SF D+ L+ + + Q+T+E NF LC
Sbjct: 1620 YLYQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQERGKKQITEE--NFQLCRRI 1677
Query: 8071 VLEAVADCFXXXXXXXXXXXXXXXXXAG---FLVPLEDLVYNDAPWVDSSSLSGKRFVHP 8241
+ E + L+P + L YND PW+ S ++ H
Sbjct: 1678 ISEGIWSLIREKRQEFCEKNYGKILLPDTNLLLLPAKSLCYNDCPWIKVKD-STVKYCHA 1736
Query: 8242 SINSDMANRLGIQSLR-----------CISLVDNDITQDLPCMDFTKLKELLSLYASKXX 8388
I ++A +LG R C + + + Q +++K +L+ Y S+
Sbjct: 1737 DIPREVAVKLGAIPKRHKALERYASNICFTALGTEFGQKEKLT--SRIKSILNAYPSEKE 1794
Query: 8389 XXXXXXXXADCCKVKKLHIIFDKREHPRKTLLQHNLGEFQGPAIVAILEGVTLTREEICS 8568
AD K ++ +FD R+HP + QGPA+ + T +++
Sbjct: 1795 MLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPAL-CVYNNQPFTEDDVRG 1853
Query: 8569 LQLLSQWRIKG---ETLNYGLGLLSCYFMCDLLSIVSGG-YFYMFDPQGATLSASTTQAP 8736
+Q L + +G +T +YG+G S Y + D S +SG +FDP +T+ +P
Sbjct: 1854 IQNLGKGTKEGNPCKTGHYGIGFNSVYHITDCPSFISGNDILGIFDPHARYAPGATSVSP 1913
Query: 8737 AGKMFSLIGTNLVERFSDQFNPMLIGQDKAWSLTDSTIIRMPL----STEILKDGFEAGL 8904
G+MF + + +FSD + L + L + T+ R PL ++ +
Sbjct: 1914 -GRMFRDLDADFRTQFSDVLDLYL---GNHFKLDNCTMFRFPLRNAEMAQVSEISSVPSS 1969
Query: 8905 DR-VKQISDQFLENASRILIFLKSVSQVSFSTWEQGNAQPHQDYTL--HIDSASAIMRNP 9075
DR V+ + D+ + + +L+FL + ++S ++ + Y++ I + R
Sbjct: 1970 DRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSVKGKITDGDRLKRKQ 2029
Query: 9076 FAEKNLKTSKLSRIFGSSNSGVKSRIIEVNLHIGENKLLDRWLVVLSKGSGQ----SQNM 9243
F + + R + V+ ++ E L WL+ G S+++
Sbjct: 2030 FHASVIDSVTKKRQL--KDIPVQQITYTMDTEDSEGN-LTTWLICNRSGFSSMEKVSKSV 2086
Query: 9244 ARGRKYLAYNLTPVAGVAAHVSRNGRPVDVHAASPIMSPLPLSGSVNLPVTILGCFLIRN 9423
K L P GVAA ++ N + H A LPLS LP + G F + +
Sbjct: 2087 ISAHKNQDITLFPRGGVAACITHNYK--KPHRA---FCFLPLSLETGLPFHVNGHFAL-D 2140
Query: 9424 NCGRFLFKNKNERAMSEPQLDAGDILIDAWNKELMSC-VRDSYIEIVV 9564
+ R L+++ N G + WN LM+ + +Y+E+++
Sbjct: 2141 SARRNLWRDDN-----------GVGVRSDWNNSLMTALIAPAYVELLI 2177
Score = 93.6 bits (231), Expect = 8e-17
Identities = 244/1197 (20%), Positives = 448/1197 (37%), Gaps = 122/1197 (10%)
Frame = +1
Query: 6202 ILWTP--GQRGHPTVEWIRVLWSYLKLS-CDDLSVFSKWPILP----VEDGCLMQLI--- 6351
+ W P + HP++ W++++W L + +DL++F + P++P ED ++LI
Sbjct: 12 VQWYPFSEDKRHPSLSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTLLNEDQTCVELIRLR 71
Query: 6352 LNSNVIRDDGWS----ENMSSLLLKCGCRFLNR-ELPVEHPQLETFVQPPTATGILNALL 6516
+ S VI DD E ++ ++ K G L R + ++HP ++ ++ P + IL +
Sbjct: 72 IPSVVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSIQHPLVKKYIHSPLPSAILQIME 131
Query: 6517 AISGGHENIKGIFLNVSEGELHELRNFILQSKWFSGGHMNEVHFETIKHLPIFE--SYRS 6690
I + + ++ LR F+ S +E I+ L IF+ ++ S
Sbjct: 132 KIP--LQKLCNQIASLLPTHKDALRKFLA-----SLTDTSEKEKRIIQELTIFKRINHSS 184
Query: 6691 RKLVSLNCPVKWLKPDGIREDLLDD---DFVRLDSERERTI-FKRYLQIKEPSKMEFYKA 6858
+ +S +K K L D +DS E TI L+I++ K
Sbjct: 185 DQGISSYTKLKGCKVLDHTAKLPTDLRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLKF 244
Query: 6859 CVLNRMSEFLSQQEA---LLAILHDLNDLVVADVSLQCAISTTPFVLAANGLWQQPSRLY 7029
+ + + F +Q+E +L IL +L+ L + ++ + F+ + G L+
Sbjct: 245 VLKDIGNAFYTQEEVTQLMLWILENLSSLKNENSNVLDWLMPLKFIHMSQGHVVAAGDLF 304
Query: 7030 DPRVPALQELLH--KEVYFPSEKFSDSKILDALVGLGLR--TTLDCSTYLDAARSVSMLH 7197
DP + L++L + +E FP F+ IL +L +GL+ ++L + AR + L
Sbjct: 305 DPDIEVLRDLFYNEEEACFPPTIFTSPDILHSLRQIGLKNESSLKEKDVVQVARKIEAL- 363
Query: 7198 DLGDLEASRYGRRLLFHIKTLSIKLSSKTGEANHDESQNIMSITSEDSFDGXXXXXXXXX 7377
+ + + L+ KTL + L+
Sbjct: 364 ---QVSSCQNQDVLMKKAKTLLLVLNK--------------------------------- 387
Query: 7378 XXXLGSLLTQQSEDEFWCQLRSIPWCPICLDPPIE---GIPWL-ESSNLVASPDRVRPKS 7545
L Q SE + L+ I W P C + P + W + NL A PD + +
Sbjct: 388 ----NQTLLQSSEGKM--ALKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPD-MCDAA 440
Query: 7546 QMFLVSATMHLLDGECQSSYLHQKLGWMDCLTIDILCRQLIEISKSYKEQKSRSSVNPEF 7725
LV +++ L+ E L Q L TI+ + + + Y + +F
Sbjct: 441 HAVLVGSSLPLV--ESVHVNLEQALSIFTKPTINAVLKHFKTVVDWYTSKTFSDEDYYQF 498
Query: 7726 ESMLQSQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDF--VSADVLSFDSPVKFT 7899
+ +L ++ L E ++ F ALK PWVW G +F ++ V+ +
Sbjct: 499 QHILLEIYGFMHDHLSE--GKDSFKALK-----FPWVWTGKNFCPLAQAVIKPTHDLDLQ 551
Query: 7900 PYLYVVPSELSDFKELLLELG--VRLSFDAADYMNTLQHLQNDIKGSQLTDEQ-INFVLC 8070
PYLY VP ++ F +L G L+ D + +L++D + S+ +Q ++ +L
Sbjct: 552 PYLYNVPKTMAKFHQLFKACGSIEELTSDHISMVIQKVYLKSDQELSEEESKQNLHLMLN 611
Query: 8071 VLE-AVADCFXXXXXXXXXXXXXXXXXAGFLVPLEDLVYNDAPWVD-----SSSLSGKRF 8232
++ ++ + P+ + Y D D S+
Sbjct: 612 IMRWLYSNQIPASPNTPVPIYHSRNPSKLVMKPIHECCYCDIKVDDLNDLLEDSVEPIIL 671
Query: 8233 VHPSINSDMANRLGIQ--SLRCISLVDNDITQDLPCMDFT-KLKELLSLYASKXXXXXXX 8403
VH I A L + S R I+ + Q T ++K +L Y S
Sbjct: 672 VHEDIPMKTAEWLKVPCLSTRLINPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKEL 731
Query: 8404 XXXADCCKVKKLHIIFDKREHP--RKTLLQHNLGEFQGPAIVAILEGVTLTREEICSLQL 8577
AD + + D R + R+ LL + GPA+ + + + ++
Sbjct: 732 LQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWS-FNNSEFSDSDFLNITR 790
Query: 8578 LSQWRIKGE---TLNYGLGLLSCYFMCDLLSIVSGGYFYMFDPQGATLS--ASTTQAPAG 8742
L + +GE +GLG S Y + D+ I+S + MFDP +S P
Sbjct: 791 LGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDRSNPGI 850
Query: 8743 KMFSLIGTNLVERFSDQFNPML--------IGQDKAWSLTDSTIIRMPLSTEILKDGFEA 8898
K+ + +F +QF P + + + +S + T+ R+ T+ E
Sbjct: 851 KINWSKQQKRLRKFPNQFKPFIDVFGCQLPLAVEAPYSY-NGTLFRLSFRTQQEAKVSEV 909
Query: 8899 -----GLDRVKQISDQFLENASRILIFLKSVSQ--VSFSTWEQGNAQPHQDYTLHIDS-- 9051
+ + D+F R++IF +SV+ + + E+ N QD T+ I
Sbjct: 910 SSTCYNTADIYSLVDEFSLCGHRLIIFTQSVNSMYLKYLKIEETNPSLAQD-TIIIKKKV 968
Query: 9052 -ASAIMRNPFAEKNLKTSKLSRIFGSSNSGV------KSRIIEVNL----HI-------- 9174
S + P + +KL + SSN + S I+++ + H+
Sbjct: 969 CPSKALNAPVLSVLKEAAKLMKTCSSSNKKLPTDVPKSSCILQITVEEFHHVFRRIADLQ 1028
Query: 9175 --------------------GENKL-----------LDRWLVVLSKGSGQSQNMARGRKY 9261
G++K WL+ +G++ +
Sbjct: 1029 SPLFRGPDDDPATLFEMAKSGQSKKPSDELPQKTVDCTTWLICTCMDTGEALKFSLNESG 1088
Query: 9262 LAYNLTP--VAGVAAHVSRNGRPVDVHAASPIMSPLPLSGSVNLPVTILGCFLIRNN 9426
L P GV H ++ + + LPL LP+ I GCF + +N
Sbjct: 1089 RRLGLVPCGAVGVLLHETQEQKWTVKPHIGEVFCYLPLRIKTGLPIHINGCFAVTSN 1145
Score = 82.0 bits (201), Expect = 2e-13
Identities = 100/490 (20%), Positives = 198/490 (40%), Gaps = 32/490 (6%)
Frame = +1
Query: 11236 ELEVLSSLPIFKTVTGSYTHLQRHGLCIISGDSFLKPYDE-----CCFCYLPDSVECHFL 11400
++++L SLP +K+++G Y + + G C + S E +L + V L
Sbjct: 2653 DIKILKSLPCYKSISGRYMSIAKFGTCYVLTKSIPSAEVEKWTQSSSSAFLEEKVHLKEL 2712
Query: 11401 -QALGVTVLHNHQTLVRFGLAEFESRSQSEREDILIYVYGNWLDLEVDSDVIEALREA-K 11574
+ LG + + + ++ L + E+ S + + LIY+ +E S++ E L E +
Sbjct: 2713 YEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLASIEEPSEIKEQLFEKLE 2772
Query: 11575 FVRNSDEFSSELSKSKDLFDPSDTLLVSVFFGERKRFPGERFSS--------------EG 11712
+ + ++ L ++K +D + + V E+ P E F
Sbjct: 2773 SLLIIHDANNRLKQAKHFYDRT-VRVFEVMLPEKLFIPKEFFKKLEQVIKPKNQAAFMTS 2831
Query: 11713 WLRILRKAGLRTAAEADVILECAKRVEFLGNERNRSSEEDDFETDLVHSEKDISVELSTL 11892
W+ LR GL+ A +L+ AK + N N S E D++ + L
Sbjct: 2832 WVEFLRNIGLKYALSQQQLLQFAKEISVRANTENWSKETLQSTVDIL-LHHIFQERMDLL 2890
Query: 11893 AGSVIEAILLNFAGFYSTAFCNTLGQIACVPAESGFPSLGG-----RKGGKRVLTRYSEA 12057
+G+ ++ + L C + + + G + G +V ++ +
Sbjct: 2891 SGNFLKELSL------IPFLCPERAPAEYIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQC 2944
Query: 12058 VLLRDWPLAWSSVPILSTQRFIPPGFSWTALRLKSPPIFSTVLKHLQVIGRNGGEDTLAH 12237
+L+ L W+S PIL + L VL L V + + +
Sbjct: 2945 DVLQ---LLWTSCPILPEKATPLSIKEQEGSDLAPQEQLEQVLNMLNVNLDPPLDKVINN 3001
Query: 12238 WPNDPNVMTIDVTSCEV-LKYLEIVWDSLTTSDI---LELQKVAFLPAANGTRLVGASSL 12405
N N+ T+D + K L +++ L+ +L+ VAF+ +G +L+ +
Sbjct: 3002 CRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEEV 3061
Query: 12406 FVRLPI--NLSPFAFELPSLYLPFLNILKDLGLNDVLSVAAAKDILSKLQKLCGYRRLNP 12579
+ L + P+ ++LP F + K LG D++S ++LS++ K ++L+P
Sbjct: 3062 VINLEYEADFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKSSEGKQLDP 3121
Query: 12580 NELRAVMEIL 12609
NE+R V ++
Sbjct: 3122 NEMRTVKRVV 3131
Score = 64.7 bits (156), Expect = 4e-08
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 16/169 (9%)
Frame = +1
Query: 3475 LRQELALAMPKIYSILARLLGSDEMDIVKAVLEGSRWIWVGDGFATLS--EVV--LDGPL 3642
L +E+ K+ + L +++ + + L G ++ V DG+ L EVV L+
Sbjct: 3011 LDEEMVKTRAKVLRSIYEFLSAEKREF-RFQLRGVAFVMVEDGWKLLKPEEVVINLEYEA 3069
Query: 3643 QLVPYIRVIPTDLAVFRGLFVELGVREFLTPSDYADVLCRIAVRKGTSPLDPQEIRAAVL 3822
PY+ +P +L F LF LG + ++ Y +VL RI LDP E+R
Sbjct: 3070 DFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKSSEGKQLDPNEMRTVKR 3129
Query: 3823 IAQQLAEAQFLDKVTI------------YLPDVSGRLFPSSDLVYNDAP 3933
+ L ++ D V + YLP G+L SS LV++DAP
Sbjct: 3130 VVSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGKLVKSSILVFDDAP 3178
Score = 42.7 bits (99), Expect = 0.16
Identities = 66/263 (25%), Positives = 116/263 (44%), Gaps = 16/263 (6%)
Frame = +1
Query: 11059 KCLPSPSVSLGQAIASKLAEGKRAGYIADIASFPTFGRDELFTLLANDFSSSGSSYQAYE 11238
K + SP S I K+ K IA + PT +D L LA+ +S E
Sbjct: 116 KYIHSPLPSAILQIMEKIPLQKLCNQIASL--LPTH-KDALRKFLASLTDTSEK-----E 167
Query: 11239 LEVLSSLPIFKTVT-------GSYTHLQRHGLCIISGDSFLKPYDECCFCYLPDSVECHF 11397
++ L IFK + SYT L+ C + + P D + DS +
Sbjct: 168 KRIIQELTIFKRINHSSDQGISSYTKLKG---CKVLDHTAKLPTDLRLSVSVIDSSDEAT 224
Query: 11398 LQALGVTVLHNHQTL--VRFGLAEFESR--SQSEREDILIYVYGNWLDLEVD-SDVIEAL 11562
++ + + +T ++F L + + +Q E +++++ N L+ + S+V++ L
Sbjct: 225 IRLANMLKIEKLKTTSCLKFVLKDIGNAFYTQEEVTQLMLWILENLSSLKNENSNVLDWL 284
Query: 11563 REAKFVRNSDEFSSELSKSKDLFDPSDTLLVSVFFGERKR-FPGERFSSEGWLRILRKAG 11739
KF+ S + + DLFDP +L +F+ E + FP F+S L LR+ G
Sbjct: 285 MPLKFIHMSQ---GHVVAAGDLFDPDIEVLRDLFYNEEEACFPPTIFTSPDILHSLRQIG 341
Query: 11740 LRTAA---EADVILECAKRVEFL 11799
L+ + E DV+ + A+++E L
Sbjct: 342 LKNESSLKEKDVV-QVARKIEAL 363
Score = 41.6 bits (96), Expect = 0.37
Identities = 40/168 (23%), Positives = 65/168 (37%), Gaps = 11/168 (6%)
Frame = +1
Query: 7726 ESMLQSQIPLLYTRLQELSRENDFLALKSALSGVPWVWLGDDFVSAD----VLSFDSPVK 7893
E M++++ +L + + LS E + L GV +V + D + V++ +
Sbjct: 3013 EEMVKTRAKVLRSIYEFLSAEKR--EFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYEAD 3070
Query: 7894 FTPYLYVVPSELSDFKELLLELGVRLSFDAADYMNTLQHLQNDIKGSQLTDEQINFVLCV 8073
F PYLY +P EL F +L LG Y+ L + +G QL ++ V V
Sbjct: 3071 FKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKSSEGKQLDPNEMRTVKRV 3130
Query: 8074 LEAVADCFXXXXXXXXXXXXXXXXXA-------GFLVPLEDLVYNDAP 8196
+ + A G LV LV++DAP
Sbjct: 3131 VSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGKLVKSSILVFDDAP 3178
Database: BlastDB/NCBI/blast/db/2003_02_17_02_00_1/nr
Posted date: Feb 17, 2003 10:02 AM
Number of letters in database: 429,188,541
Number of sequences in database: 1,339,046
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
length of database: 429,188,541
effective HSP length: 144
effective length of database: 236,365,917
effective search space used: 1086101388615
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)